Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

RPRD1A LEO1 CTR9 TAF1 TAF1L

5.56e-0666775GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

RPRD1A LEO1 CTR9 TAF1 TAF1L

5.56e-0666775GO:0001098
GeneOntologyMolecularFunctionhistone acetyltransferase activity

BRCA2 TAF1 TAF1L KAT14

4.45e-0551774GO:0004402
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

BRCA2 TAF1 TAF1L KAT14

6.00e-0555774GO:0061733
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

BRCA2 TAF1 TAF1L KAT14

8.46e-0560774GO:0034212
GeneOntologyMolecularFunctionH3K27me3 modified histone binding

TAF1 TAF1L

1.46e-045772GO:0061628
GeneOntologyMolecularFunctionN-acetyltransferase activity

BRCA2 TAF1 TAF1L KAT14

2.35e-0478774GO:0008080
GeneOntologyMolecularFunctionRNA polymerase II complex binding

RPRD1A LEO1 CTR9

4.56e-0439773GO:0000993
GeneOntologyMolecularFunctionRNA polymerase I general transcription initiation factor activity

TAF1 TAF1L

5.19e-049772GO:0001181
GeneOntologyMolecularFunctionN-acyltransferase activity

BRCA2 TAF1 TAF1L KAT14

6.52e-04102774GO:0016410
GeneOntologyMolecularFunctionRNA polymerase core enzyme binding

RPRD1A LEO1 CTR9

6.96e-0445773GO:0043175
GeneOntologyMolecularFunctionacetyltransferase activity

BRCA2 TAF1 TAF1L KAT14

7.02e-04104774GO:0016407
GeneOntologyMolecularFunctionRNA polymerase II C-terminal domain binding

RPRD1A LEO1

7.89e-0411772GO:0099122
GeneOntologyMolecularFunctionhistone modifying activity

BRCA2 TAF1 TAF1L UTY KAT14

1.92e-03229775GO:0140993
GeneOntologyMolecularFunctionRNA polymerase binding

RPRD1A LEO1 CTR9

2.03e-0365773GO:0070063
GeneOntologyCellularComponentCdc73/Paf1 complex

LEO1 CTR9

2.57e-047742GO:0016593
GeneOntologyCellularComponentRNA polymerase II, holoenzyme

LEO1 CTR9 TAF1 TAF1L

2.81e-0489744GO:0016591
GeneOntologyCellularComponentcell body fiber

HTR2A PENK

6.66e-0411742GO:0070852
GeneOntologyCellularComponentnuclear DNA-directed RNA polymerase complex

LEO1 CTR9 TAF1 TAF1L

6.96e-04113744GO:0055029
GeneOntologyCellularComponentDNA-directed RNA polymerase complex

LEO1 CTR9 TAF1 TAF1L

7.68e-04116744GO:0000428
GeneOntologyCellularComponentRNA polymerase complex

LEO1 CTR9 TAF1 TAF1L

8.45e-04119744GO:0030880
GeneOntologyCellularComponenttranscription elongation factor complex

LEO1 CTR9 AFF4

1.03e-0356743GO:0008023
MousePhenoabnormal mortality induced by ionizing radiation

BRCA2 ING1 PARG FUS IP6K2

5.00e-0655645MP:0020149
MousePhenoabnormal response to radiation

BRCA2 ING1 PARG FUS IP6K2

5.98e-0657645MP:0012734
MousePhenoincreased mortality induced by ionizing radiation

BRCA2 ING1 PARG FUS

8.50e-0551644MP:0003992
DomainTSP_3

THBS2 THBS4 COMP

6.44e-075763PF02412
DomainTSP3

THBS2 THBS4 COMP

6.44e-075763PS51234
DomainTSP_CTER

THBS2 THBS4 COMP

6.44e-075763PS51236
Domain-

THBS2 THBS4 COMP

6.44e-0757634.10.1080.10
DomainThrombospondin_C

THBS2 THBS4 COMP

6.44e-075763IPR008859
DomainTSP_C

THBS2 THBS4 COMP

6.44e-075763PF05735
DomainThrombospondin_3_rpt

THBS2 THBS4 COMP

6.44e-075763IPR017897
DomainThrombospondin_3-like_rpt

THBS2 THBS4 COMP

6.44e-075763IPR003367
DomainTSP_type-3_rpt

THBS2 THBS4 COMP

6.44e-075763IPR028974
DomainTAF_II_230-bd

TAF1 TAF1L

1.63e-052762IPR009067
DomainTFIID_sub1_DUF3591

TAF1 TAF1L

1.63e-052762IPR022591
Domain-

TAF1 TAF1L

1.63e-0527621.10.1100.10
DomainTBP-binding

TAF1 TAF1L

1.63e-052762PF09247
DomainDUF3591

TAF1 TAF1L

1.63e-052762PF12157
DomainTAF1_animal

TAF1 TAF1L

1.63e-052762IPR011177
DomainPDZ

IL16 MAGI3 LNX1 PREX1 PREX2 RGS12

3.10e-05148766SM00228
Domain-

IL16 MAGI3 LNX1 PREX1 PREX2 RGS12

3.34e-051507662.30.42.10
DomainPDZ

IL16 MAGI3 LNX1 PREX1 PREX2 RGS12

3.47e-05151766PS50106
DomainPDZ

IL16 MAGI3 LNX1 PREX1 PREX2 RGS12

3.60e-05152766IPR001478
DomainThbs/COMP_coiled-coil

THBS4 COMP

4.89e-053762IPR024665
DomainCOMP

THBS4 COMP

4.89e-053762PF11598
DomainPDZ

IL16 MAGI3 LNX1 PREX2 RGS12

2.74e-04141765PF00595
DomainEGF_CA

THBS2 THBS4 COMP VCAN

1.55e-03122764SM00179
DomainEGF-like_Ca-bd_dom

THBS2 THBS4 COMP VCAN

1.64e-03124764IPR001881
Domainzf-RanBP

YAF2 FUS

3.58e-0322762PF00641
DomainDEP

PREX1 PREX2

3.58e-0322762PF00610
DomainDEP

PREX1 PREX2

3.58e-0322762PS50186
DomainDEP

PREX1 PREX2

3.58e-0322762SM00049
DomainDEP_dom

PREX1 PREX2

3.91e-0323762IPR000591
DomainTSPN

THBS2 THBS4

3.91e-0323762SM00210
DomainZnF_RBZ

YAF2 FUS

3.91e-0323762SM00547
DomainZF_RANBP2_2

YAF2 FUS

3.91e-0323762PS50199
DomainZF_RANBP2_1

YAF2 FUS

4.26e-0324762PS01358
DomainZnf_RanBP2

YAF2 FUS

4.61e-0325762IPR001876
DomainBromodomain_CS

TAF1 TAF1L

4.99e-0326762IPR018359
DomainEGF_CA

THBS2 THBS4 COMP

5.20e-0386763PF07645
Domain-

THBS2 THBS4 COMP

6.85e-03957632.60.120.200
DomainEGF_Ca-bd_CS

THBS4 COMP VCAN

7.26e-0397763IPR018097
DomainPID

ANKS1B RGS12

7.49e-0332762PS01179
DomainEGF_CA

THBS4 COMP VCAN

7.68e-0399763PS01187
PathwayREACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS

LEO1 CTR9 TAF1 TAF1L AFF4 IWS1

5.52e-0781536M865
PathwayREACTOME_RNA_POLYMERASE_II_PRE_TRANSCRIPTION_EVENTS

LEO1 CTR9 TAF1 TAF1L AFF4 IWS1

6.38e-0783536MM15314
PathwayREACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX

LEO1 CTR9 AFF4 IWS1

6.50e-0558534M805
PathwayREACTOME_FORMATION_OF_RNA_POL_II_ELONGATION_COMPLEX

LEO1 CTR9 AFF4 IWS1

6.95e-0559534MM14504
Pubmed

Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.

THBS2 THBS4 COMP

1.08e-07578330622267
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

PPP4R1 JCAD RPRD1A LEO1 CTR9 TSPYL2 EIF4G2 ANKS1B MAGI3 SYNPO TAF1 PJA1 LNX1 PREX1 AFF4

1.48e-071285781535914814
Pubmed

Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.

THBS2 THBS4 COMP

6.03e-07878324460873
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

CEP170 CCDC8 GAPVD1 RPRD1A GPBP1 UBR5 CTR9 TSPYL2 FUS

6.45e-0744078934244565
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CEP170 JCAD CCDC8 GAPVD1 GBF1 GPBP1 MYO9A ZNF629 MAGI3 AKAP11 RGS12

3.45e-06861781136931259
Pubmed

Methylation and Expression of Nonclustered Protocadherins Encoding Genes and Risk of Precancerous Gastric Lesions in a High-Risk Population.

PCDH10 PCDH17

4.97e-06278230213786
Pubmed

Cytotoxic Programming of CD4+ T Cells Is Regulated by Opposing Actions of the Related Transcription Factors Eos and Aiolos.

IKZF3 IKZF4

4.97e-06278238363226
Pubmed

P-Rex1 and P-Rex2 RacGEFs and cancer.

PREX1 PREX2

4.97e-06278228710285
Pubmed

Activity-dependent FUS dysregulation disrupts synaptic homeostasis.

FUS MEOX2

4.97e-06278225324524
Pubmed

Control of cerebellar long-term potentiation by P-Rex-family guanine-nucleotide exchange factors and phosphoinositide 3-kinase.

PREX1 PREX2

4.97e-06278220694145
Pubmed

Biophysical characterization of the signature domains of thrombospondin-4 and thrombospondin-2.

THBS2 THBS4

4.97e-06278216246837
Pubmed

Taf1 knockout is lethal in embryonic male mice and heterozygous females show weight and movement disorders.

TAF1 TAF1L

4.97e-06278238804708
Pubmed

TAFII250, Egr-1, and D-type cyclin expression in mice and neonatal rat cardiomyocytes treated with doxorubicin.

TAF1 TAF1L

4.97e-06278210070062
Pubmed

Associations of THBS2 and THBS4 polymorphisms to gastric cancer in a Southeast Chinese population.

THBS2 THBS4

4.97e-06278227160021
Pubmed

Sustained expression of a neuron-specific isoform of the Taf1 gene in development stages and aging in mice.

TAF1 TAF1L

4.97e-06278222842574
Pubmed

Frameshift Mutations in the Mononucleotide Repeats of TAF1 and TAF1L Genes in Gastric and Colorectal Cancers with Regional Heterogeneity.

TAF1 TAF1L

4.97e-06278227571988
Pubmed

Striatal Cholinergic Dysregulation after Neonatal Decrease in X-Linked Dystonia Parkinsonism-Related TAF1 Isoforms.

TAF1 TAF1L

4.97e-06278234403156
Pubmed

Variants within the COMP and THBS2 genes are not associated with Achilles tendinopathy in a case-control study of South African and Australian populations.

THBS2 COMP

4.97e-06278223875975
Pubmed

COMP and TSP-4 interact specifically with the novel GXKGHR motif only found in fibrillar collagens.

THBS4 COMP

4.97e-06278230464261
Pubmed

P-Rex2 regulates Purkinje cell dendrite morphology and motor coordination.

PREX1 PREX2

4.97e-06278218334636
Pubmed

Increased cortical expression of two synaptogenic thrombospondins in human brain evolution.

THBS2 THBS4

4.97e-06278217182969
Pubmed

Integrated genomic profiling identifies candidate genes implicated in glioma-genesis and a novel LEO1-SLC12A1 fusion gene.

SLC12A1 LEO1

4.97e-06278220196086
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

PPP4R1 IKZF3 LEO1 BRCA2 UBR5 MYO9A CTR9 ZNF629 KAT14

6.87e-0658878938580884
Pubmed

Large scale association analysis for identification of genes underlying premature coronary heart disease: cumulative perspective from analysis of 111 candidate genes.

THBS2 THBS4

1.49e-05378215121769
Pubmed

Regulated expression of TAF1 in 1-cell mouse embryos.

TAF1 TAF1L

1.49e-05378216822332
Pubmed

Pathological Significance and Prognostic Roles of Thrombospondin-3, 4 and 5 in Bladder Cancer.

THBS4 COMP

1.49e-05378233910854
Pubmed

Thrombospondin-2 polymorphism is associated with a reduced risk of premature myocardial infarction.

THBS2 THBS4

1.49e-05378212482844
Pubmed

Thrombospondin-1, -2 and -5 have differential effects on vascular smooth muscle cell physiology.

THBS2 COMP

1.49e-05378226168731
Pubmed

Depletion of trypanosome CTR9 leads to gene expression defects.

LEO1 CTR9

1.49e-05378222532828
Pubmed

Association between single nucleotide polymorphisms in thrombospondins genes and coronary artery disease: A meta-analysis.

THBS2 THBS4

1.49e-05378225976449
Pubmed

TAFII55 binding to TAFII250 inhibits its acetyltransferase activity.

TAF1 TAF1L

1.49e-05378211592977
Pubmed

PARP-1 Activation Directs FUS to DNA Damage Sites to Form PARG-Reversible Compartments Enriched in Damaged DNA.

PARG FUS

1.49e-05378231067465
Pubmed

Functional substitution for TAF(II)250 by a retroposed homolog that is expressed in human spermatogenesis.

TAF1 TAF1L

1.49e-05378212217962
Pubmed

TAF7: a possible transcription initiation check-point regulator.

TAF1 TAF1L

1.49e-05378216407123
Pubmed

Polymorphisms in thrombospondin genes and myocardial infarction: a case-control study and a meta-analysis of available evidence.

THBS2 THBS4

1.49e-05378218178577
Pubmed

Human transcription factor protein interaction networks.

FLG TSHZ3 CCDC8 IKZF3 YAF2 ING1 ZNF629 TAF1 CLPX RREB1 TAF1L KAT14 DDX10

1.65e-051429781335140242
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FLG UBTD2 LEO1 CTR9 BIVM ANKS1B MAGI3 CEP295 SYNPO OTUD3 FUS CLPX PREX1

1.81e-051442781335575683
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

CEP170 PPP4R1 GAPVD1 LEO1 UBR5 CTR9 EIF4G2 ZC3H12C PJA1 AAGAB IWS1

1.99e-051038781126673895
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

MYOT PENK TSPYL2 TAF1 PJA1 TAF1L UTY PREX2 ZBBX

2.03e-0567478937196079
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

JCAD GAPVD1 GPBP1 BRCA2 UBR5 EIF4G2 MAGI3 CEP295 FUS RGS12

2.09e-05853781028718761
Pubmed

Elongin A regulates transcription in vivo through enhanced RNA polymerase processivity.

LEO1 CTR9 AFF4

2.72e-052678333298525
Pubmed

Rho GEFs and cancer: linking gene expression and metastatic dissemination.

PREX1 PREX2

2.97e-05478223033535
Pubmed

Protein Degradation of RNA Polymerase II-Association Factor 1(PAF1) Is Controlled by CNOT4 and 26S Proteasome.

LEO1 CTR9

2.97e-05478225933433
Pubmed

Immunohistochemical localisation of thrombospondin in human megakaryocytes and platelets.

THBS2 THBS4

2.97e-0547826338048
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

PPP4R1 SLC12A1 RPRD1A COMP UBR5 CTR9 ZNF629 CLPX CCDC140 KAT14 PREX2 IWS1

3.84e-051327781232694731
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CEP170 IL16 UBR5 TSPYL2 ZNF629 CEP295 TAF1 CLPX RREB1 KAT14 AFF4

3.85e-051116781131753913
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TSHZ3 GAPVD1 BRCA2 UBR5 TAF1 RREB1 KAT14

4.37e-0541878734709266
Pubmed

Skeletal abnormalities in mice lacking extracellular matrix proteins, thrombospondin-1, thrombospondin-3, thrombospondin-5, and type IX collagen.

THBS4 COMP

4.94e-05578218467703
Pubmed

Eos and pegasus, two members of the Ikaros family of proteins with distinct DNA binding activities.

IKZF3 IKZF4

4.94e-05578210978333
Pubmed

Structural basis for evolutionarily conserved interactions between TFIIS and Paf1C.

LEO1 CTR9

4.94e-05578237696373
Pubmed

COL3A1, CXCL8, VCAN, THBS2, and COL1A2 are correlated with the onset of biliary atresia.

THBS2 VCAN

4.94e-05578236930067
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

CEP170 BRCA2 ING1 EIF4G2 TAF1 FUS RREB1 TAF1L AFF4 DDX10

5.36e-05954781036373674
Pubmed

Context-specific function of the LIM homeobox 1 transcription factor in head formation of the mouse embryo.

PCDH10 PCDH17 MEOX2

6.74e-053578325977363
Pubmed

Recurrent genomic alterations characterize medulloblastoma arising from DNA double-strand break repair deficiency.

BRCA2 MEOX2

7.40e-05678219164512
Pubmed

P-Rex and Vav Rac-GEFs in platelets control leukocyte recruitment to sites of inflammation.

PREX1 PREX2

7.40e-05678225538043
Pubmed

Direct interactions between the Paf1 complex and a cleavage and polyadenylation factor are revealed by dissociation of Paf1 from RNA polymerase II.

LEO1 CTR9

7.40e-05678218469135
Pubmed

The PAF complex synergizes with MLL fusion proteins at HOX loci to promote leukemogenesis.

LEO1 CTR9

7.40e-05678220541477
Pubmed

Transforming growth factor-beta regulates basal transcriptional regulatory machinery to control cell proliferation and differentiation in cranial neural crest-derived osteoprogenitor cells.

TAF1 TAF1L

7.40e-05678219959467
Pubmed

Meiosis-Specific C19orf57/4930432K21Rik/BRME1 Modulates Localization of RAD51 and DMC1 to DSBs in Mouse Meiotic Recombination.

BRCA2 BRME1

1.04e-04778232460033
Pubmed

P-Rex1 and Vav1 cooperate in the regulation of formyl-methionyl-leucyl-phenylalanine-dependent neutrophil responses.

PREX1 PREX2

1.04e-04778221178006
Pubmed

P-Rex1 links mammalian target of rapamycin signaling to Rac activation and cell migration.

PREX1 PREX2

1.04e-04778217565979
Pubmed

The parafibromin tumor suppressor protein is part of a human Paf1 complex.

LEO1 CTR9

1.04e-04778215632063
Pubmed

Elongator and codon bias regulate protein levels in mammalian peripheral neurons.

BRCA2 VCAN

1.04e-04778229497044
Pubmed

PAF1 complex interactions with SETDB1 mediate promoter H3K9 methylation and transcriptional repression of Hoxa9 and Meis1 in acute myeloid leukemia.

LEO1 CTR9

1.04e-04778229774127
Pubmed

Regulation of transcriptional elongation in pluripotency and cell differentiation by the PHD-finger protein Phf5a.

LEO1 CTR9

1.04e-04778227749823
Pubmed

SIAH1/CTR9 axis promotes the epithelial-mesenchymal transition of hepatocellular carcinoma.

CTR9 PCDH17

1.04e-04778237038329
Pubmed

Conservation of position and exclusive expression of mouse Xist from the inactive X chromosome.

TAF1 TAF1L

1.38e-0487822034279
Pubmed

Histone H3R17me2a mark recruits human RNA polymerase-associated factor 1 complex to activate transcription.

LEO1 CTR9

1.38e-04878222451921
Pubmed

The X-linked intellectual disability protein PHF6 associates with the PAF1 complex and regulates neuronal migration in the mammalian brain.

LEO1 CTR9

1.38e-04878223791194
Pubmed

P-Rex1 directly activates RhoG to regulate GPCR-driven Rac signalling and actin polarity in neutrophils.

PREX1 PREX2

1.38e-04878224659802
Pubmed

Physical mapping of 2000 kb of the mouse X chromosome in the vicinity of the Xist locus.

TAF1 TAF1L

1.38e-0487828468051
Pubmed

Association of common promoter polymorphisms of MCP1 with hepatitis B virus clearance.

THBS2 THBS4

1.38e-04878217202846
Pubmed

Genetic mapping in the region of the mouse X-inactivation center.

TAF1 TAF1L

1.38e-0487821974879
Pubmed

Deletion of Prl7d1 causes placental defects at mid-pregnancy in mice.

TAF1 TAF1L

1.38e-04878231012985
Pubmed

High-density molecular map of the central span of the mouse X chromosome.

TAF1 TAF1L

1.38e-0487821675191
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

YAF2 LEO1 ING1 CTR9 EIF4G2 ZNF629 FUS RREB1 TAF1L KAT14 IWS1

1.43e-041294781130804502
Pubmed

An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.

UBTD2 IKZF3 GCM2 GPBP1 LNX1 AAGAB IP6K2

1.58e-0451478729892012
Pubmed

An empirical framework for binary interactome mapping.

USP6 IL16 GPBP1 BRME1 KAT14

1.76e-0423178519060904
Pubmed

Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.

BRCA2 MEOX2

1.77e-04978223657012
Pubmed

The human PAF1 complex acts in chromatin transcription elongation both independently and cooperatively with SII/TFIIS.

LEO1 CTR9

1.77e-04978220178742
Pubmed

The intracellular localisation of TAF7L, a paralogue of transcription factor TFIID subunit TAF7, is developmentally regulated during male germ-cell differentiation.

TAF1 TAF1L

1.77e-04978212665565
Pubmed

Cloning and characterization of a new human Xq13 gene, encoding a putative helicase.

TAF1 TAF1L

1.77e-0497827874112
Pubmed

The BRCA2-MEILB2-BRME1 complex governs meiotic recombination and impairs the mitotic BRCA2-RAD51 function in cancer cells.

BRCA2 BRME1

1.77e-04978232345962
Pubmed

Praja1 RING-finger E3 ubiquitin ligase is a common suppressor of neurodegenerative disease-associated protein aggregation.

FUS PJA1

1.77e-04978235701899
Pubmed

The human PAF complex coordinates transcription with events downstream of RNA synthesis.

LEO1 CTR9

1.77e-04978216024656
Pubmed

HIV-1 tat binds TAFII250 and represses TAFII250-dependent transcription of major histocompatibility class I genes.

TAF1 TAF1L

1.77e-0497829751712
Pubmed

The HRPT2 tumor suppressor gene product parafibromin associates with human PAF1 and RNA polymerase II.

LEO1 CTR9

1.77e-04978215923622
Pubmed

SHP2 tyrosine phosphatase converts parafibromin/Cdc73 from a tumor suppressor to an oncogenic driver.

LEO1 CTR9

2.21e-041078221726809
Pubmed

Genetic and molecular evidence of an X-chromosome deletion spanning the tabby (Ta) and testicular feminization (Tfm) loci in the mouse.

TAF1 TAF1L

2.21e-04107822055107
Pubmed

SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.

FLG CCDC8 GOLM1 FUS CLPX

2.31e-0424578535652658
Pubmed

E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.

GAPVD1 THBS4 MYO3B BRME1 MAGI3 CEP295 PCDH10 PCDH17

2.46e-0473678829676528
Pubmed

Characterization of a murine gene expressed from the inactive X chromosome.

TAF1 TAF1L

2.70e-04117822034278
Pubmed

Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs.

TSHZ3 CCDC8 GPBP1 TSPYL2 SYNPO CLPX AAGAB PREX1

2.80e-0475078811230166
Pubmed

Transcriptomic analysis of mouse limb tendon cells during development.

THBS2 THBS4

3.23e-041278225249460
Pubmed

p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling.

HTR2A ANKS1B

3.23e-041278216537434
Pubmed

In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.

CCDC8 YAF2 UBR5 CTR9 EIF4G2 FUS CLPX PCDH10 IWS1

3.23e-0497178933306668
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

GAPVD1 GBF1 LEO1 CTR9 PARG EIF4G2 RREB1 IWS1

3.45e-0477478815302935
Pubmed

Mapping of loci and translocation breakpoints in Xq13: isolation of a conserved locus that maps close to CCG1 in human and mouse.

TAF1 TAF1L

3.81e-04137828012115
Pubmed

Requirement of tissue-selective TBP-associated factor TAFII105 in ovarian development.

TAF1 TAF1L

3.81e-041378211557891
Pubmed

Rps4 maps near the inactivation center on the mouse X chromosome.

TAF1 TAF1L

3.81e-04137821740345
InteractionZNF330 interactions

LEO1 CTR9 ZNF629 TAF1 CLPX RREB1 AFF4 IWS1 DDX10 MEOX2

8.36e-064467810int:ZNF330
InteractionYWHAZ interactions

CEP170 JCAD CCDC8 GAPVD1 GBF1 YAF2 RPRD1A GPBP1 ING1 MYO9A ZNF629 AKAP11 SYNPO FUS LNX1 RUBCN RGS12

9.25e-0613197817int:YWHAZ
InteractionYWHAG interactions

CEP170 JCAD CCDC8 GAPVD1 GBF1 GPBP1 ING1 MYO9A ZNF629 MAGI3 AKAP11 SYNPO TNFRSF10A LNX1 RUBCN RGS12

1.90e-0512487816int:YWHAG
InteractionEGLN3 interactions

CEP170 PPP4R1 JCAD CCDC8 GAPVD1 IKZF3 GBF1 GPBP1 BRCA2 UBR5 PARG AKAP11 CEP295 PJA1 CLPX LNX1

3.02e-0512967816int:EGLN3
InteractionHSF2BP interactions

TSHZ3 IL16 GCM2 GPBP1 BRCA2 ANKS1B BRME1 LNX1

3.16e-05318788int:HSF2BP
InteractionNME7 interactions

CEP170 IKZF3 MYOT LNX1 RUBCN MEOX2

3.65e-05160786int:NME7
InteractionPHF21A interactions

TSHZ3 GAPVD1 RPRD1A BRCA2 UBR5 TAF1 RREB1 KAT14

5.40e-05343788int:PHF21A
InteractionCSNK2A1 interactions

CEP170 FLG CCDC8 IL16 GBF1 YAF2 LEO1 CTR9 TSPYL2 EIF4G2 TAF1 IWS1 MEOX2

7.13e-059567813int:CSNK2A1
InteractionYWHAH interactions

CEP170 JCAD CCDC8 GAPVD1 GBF1 YAF2 GPBP1 ING1 MYO9A ZNF629 MAGI3 AKAP11 RUBCN RGS12

7.56e-0511027814int:YWHAH
InteractionMLF1 interactions

BRCA2 AKAP11 CEP295 OTUD3 MEOX2

7.73e-05113785int:MLF1
InteractionROPN1 interactions

TSHZ3 FAM153A AKAP11 LNX1

9.16e-0561784int:ROPN1
InteractionDDX23 interactions

LEO1 UBR5 CTR9 ZNF629 TAF1 FUS AFF4 IWS1 DDX10

9.73e-05480789int:DDX23
GeneFamilyPDZ domain containing

IL16 MAGI3 LNX1 PREX1 PREX2 RGS12

2.93e-061524861220
GeneFamilyTetratricopeptide repeat domain containing|Paf1/RNA polymerase II complex

LEO1 CTR9

1.03e-0464821029
GeneFamilyNon-clustered protocadherins

PCDH10 PCDH17

4.48e-041248221
GeneFamilyZinc fingers RANBP2-type |RNA binding motif containing

YAF2 FUS

1.40e-032148289
CoexpressionGSE21033_3H_VS_24H_POLYIC_STIM_DC_UP

IL16 IKZF3 SYNPO RREB1 PREX1 IP6K2

1.04e-05166786M7722
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_200

TSHZ3 THBS2 VCAN PENK PCDH10

1.34e-0586755gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200_k1
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

GPBP1 LEO1 BRCA2 UBR5 PARG EIF4G2 MAGI3 ZC3H12C PREX2 IWS1

1.72e-055327510Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_200

TSHZ3 THBS2 SLC12A1 VCAN PENK PCDH10

2.51e-05164756gudmap_developingKidney_e15.5_Pelvic Mesenchyme_200
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#2_top-relative-expression-ranked_1000

TSHZ3 THBS2 THBS4 VCAN PENK PJA1 PCDH10

1.01e-04305757gudmap_developingKidney_e15.5_Pelvic Mesenchyme_1000_k2
ToppCellNS-critical-d_16-33-Epithelial-unknown_epithelial|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TSPYL2 FUS TNFRSF10A PCDH10 REXO1L1P PCDH17

5.85e-07172786c0b5e4889aef2f168d9f6db19a63b24bfd249316
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 TSHZ3 THBS2 SYNPO PREX2

9.53e-07187786e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCelldroplet-Fat-Scat-21m-Endothelial-Cd36+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 LNX1 PREX2 PCDH17 MEOX2

9.83e-071887868671fdbc4138e6f9559920779c98628ed80f0da3
ToppCelldroplet-Fat-Scat-21m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 LNX1 PREX2 PCDH17 MEOX2

1.05e-06190786d3e46cf800a07ca9b01c78192962d223b9785d05
ToppCelldroplet-Fat-Scat-21m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 LNX1 PREX2 PCDH17 MEOX2

1.05e-06190786dd89ef1ecea20b2f6fbdc6cea4ca41b28b3ed822
ToppCellPND10|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD GAPVD1 IKZF3 EIF4G2 PREX2 AFF4

1.05e-06190786d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCelltumor_Lung-Endothelial_cells-Stalk-like_ECs|tumor_Lung / Location, Cell class and cell subclass

JCAD ADCY4 SYNPO PCDH10 PREX2 PCDH17

1.15e-0619378621fec35587ffb5c0157e54a821ce3ffd3e24e536
ToppCellfacs-GAT-Fat-3m-Endothelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 SYNPO LNX1 PREX2 PCDH17 MEOX2

1.25e-06196786b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCellfacs-GAT-Fat-3m-Endothelial-endothelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 SYNPO LNX1 PREX2 PCDH17 MEOX2

1.25e-06196786ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCellfacs-GAT-Fat-3m-Endothelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 SYNPO LNX1 PREX2 PCDH17 MEOX2

1.25e-06196786039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TSHZ3 THBS2 IL16 VCAN MYO3B PREX2

1.41e-0620078658b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellcritical-Epithelial-unknown_epithelial|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ING1 TSPYL2 TNFRSF10A PCDH10 REXO1L1P

9.43e-06161785594cf3245ec065a7685db81cd8ba2cee8d42caac
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 SYNPO PREX2 PCDH17

1.33e-051737853a9e9a09b3eeb37cbe56d650e112a8398879477f
ToppCellcritical-Epithelial-unknown_epithelial|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ING1 TSPYL2 FUS TNFRSF10A PCDH10

1.33e-051737854144b1cdefa8c37b6ac7a6d249fa5292ffb2b8b2
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 IL16 HTR2A VCAN PREX2

1.49e-051777859ec7f1e64312d26d434b3312b58386715dbad644
ToppCellmetastatic_Lymph_Node-Endothelial_cells|metastatic_Lymph_Node / Location, Cell class and cell subclass

JCAD ADCY4 PREX2 PCDH17 MEOX2

1.49e-0517778571bf5d4bc67bda37a0499e5ec01af7dd5254041d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 IL16 HTR2A VCAN PREX2

1.49e-05177785016277dfd59b1793fddaaadc2b3f41622d76ce3a
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

1.62e-0518078597e0dcb7cfbba60a782824c5e23995058609fcd4
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

GAPVD1 IKZF3 GBF1 FUS UTY

1.84e-05185785a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCellEndothelial-A-Donor_08|World / lung cells shred on cell class, cell subclass, sample id

JCAD ADCY4 PREX2 PCDH17 MEOX2

1.84e-05185785dee0b7ba2f338f0979d2306aedf52ac35a36b60c
ToppCellControl-Endothelial_cells-Endothelial_cells_(other)|Control / group, cell type (main and fine annotations)

JCAD ADCY4 PREX1 PREX2 PCDH17

1.89e-05186785c6075fe84226b370c5139066793844ad33ae2db1
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

JCAD ADCY4 PREX1 PREX2 PCDH17

1.94e-05187785fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 PREX1 PREX2 PCDH17

1.99e-05188785366a2d59b9c81d8a7659749f9c07efa46b49a39a
ToppCelldroplet-Kidney-nan-3m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 THBS2 SYNPO PREX2

1.99e-05188785ec0e241de2c8310b4417b9d4e2420d7a1662f1c0
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 PREX2 PCDH17 MEOX2

1.99e-0518878505de6677f9bb4b00fed47f4b72f4a2cd507cb0f2
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7|TCGA-Colorectal / Sample_Type by Project: Shred V9

THBS2 CCDC8 COMP VCAN ZNF629

1.99e-0518878514bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCellControl-Endothelial_cells|Control / group, cell type (main and fine annotations)

JCAD ADCY4 PREX1 PREX2 PCDH17

1.99e-051887853953b08abfea93468fc8d177bdb16ca7c6ffa1ab
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

JCAD LNX1 PREX1 PREX2 PCDH17

2.04e-05189785b6b4da51bc7f2c13a2f940540fdc61027d084835
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 PREX2 PCDH17 MEOX2

2.04e-051897858ced0381ea042ba47680a02b617a2368fa2c54c8
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

SLC12A1 MYO9A MYO3B MAGI3 UTY

2.04e-05189785830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 PREX2 PCDH17 MEOX2

2.04e-05189785403a82bb416aed13b9d31411ad17bdc4ce2a95fb
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 THBS2 SYNPO PREX2

2.10e-05190785cb8798839c27f307955fcc94a1ee40bca95b8e99
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-endothelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 LNX1 PCDH17 MEOX2

2.10e-05190785c8370c922e0cf0e0c36e02e1ed2b4053ad6a8073
ToppCelldroplet-Kidney-KIDNEY-30m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 THBS2 SYNPO PREX2

2.10e-051907855bf3d0beee69879c95265d07fba023626a7cc808
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 LNX1 PCDH17 MEOX2

2.10e-051907855174f91a880f85bb20806023aa68bd4b8ca24ea5
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

JCAD ADCY4 PREX2 PCDH17 MEOX2

2.10e-05190785141266bf411ea675fbf889b20c1b08673c45ff95
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Endothelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 LNX1 PCDH17 MEOX2

2.10e-0519078590e494cbfbed33a3a0d29bb7dae83f0c81580bcf
ToppCellfacs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 LNX1 PREX2 MEOX2

2.15e-05191785a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

GAPVD1 IKZF3 GBF1 FUS UTY

2.15e-051917859454f642c3621370fa23640b631301346b300950
ToppCellfacs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 LNX1 PREX2 MEOX2

2.15e-05191785827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 COMP PREX2 PCDH17 MEOX2

2.20e-05192785945153c41dde6e90d103206955e1707b54eb0665
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

GPBP1 UBR5 VCAN MAGI3 AFF4

2.20e-05192785916fbec1c7ab7969bda711886ac88e877e30c280
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 COMP PREX2 PCDH17 MEOX2

2.20e-051927856ab50579c63f31ca2cd41063a99b129f11c07510
ToppCelldroplet-Kidney-nan-18m-Endothelial-kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 THBS2 PREX2 PCDH17

2.20e-05192785144503af50274eaed5cf6effa892c640eab28663
ToppCelldroplet-Kidney-nan-18m-Endothelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JCAD ADCY4 THBS2 PREX2 PCDH17

2.20e-05192785c96736bb3a6bb052678b1b078f7823063ca69e6d
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLG GCM2 COMP MYLK4 TAF1L

2.26e-05193785315840bc48899f3a36d57b19197509de19716e3d
ToppCellIPF-Endothelial-VE_Arterial|IPF / Disease state, Lineage and Cell class

JCAD ADCY4 SYNPO PREX2 PCDH17

2.26e-05193785bf83b1fe9d38408f30eee4eb634341c04ef82791
ToppCellPCW_10-12-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.26e-05193785643f992dbce639e7d147924d8b8f455fcebf215a
ToppCellPND10-Endothelial-Endothelial_blood-vessel|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD ADCY4 PREX2 RGS12 PCDH17

2.26e-051937851d8acf81dcbfe81c7a73ce50c9f38fe0cbc74486
ToppCellIPF-Endothelial-VE_Arterial|World / Disease state, Lineage and Cell class

JCAD ADCY4 SYNPO PREX2 PCDH17

2.26e-0519378570a9aadda83a97e06e9bc2d1327ce60dd3c58767
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.26e-0519378501c71aa48875b5ad6c50cc810a72862e72f26ad0
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

GPBP1 UBR5 VCAN MAGI3 AFF4

2.26e-05193785e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD ADCY4 PREX2 RGS12 PCDH17

2.26e-05193785097a244cf37ce6c1ace9bae56beb7de59442cd6b
ToppCellPND10-Endothelial|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD ADCY4 PREX2 RGS12 PCDH17

2.26e-05193785f3c743b340fc588bc8effd375b12e2c7cbfa49d2
ToppCellTCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-3|TCGA-Stomach / Sample_Type by Project: Shred V9

THBS2 THBS4 HTR2A VCAN MEOX2

2.32e-051947852260cd817a6661e5eb6645b0c6786e18fd58371e
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 PREX1 PREX2 PCDH17

2.32e-05194785f76808666fb875fc787751cbfd924d9be20a8192
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD ADCY4 PREX2 RGS12 PCDH17

2.32e-051947851b382508453c5b08fb617f626b230adf3b6cff99
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 PREX1 PREX2 PCDH17

2.32e-0519478574a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCellEndothelial-A-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

JCAD ADCY4 SYNPO PREX2 PCDH17

2.32e-05194785e656ac5539e59e321b46706cb8cc423b2c3358a0
ToppCell10x5'v1-week_14-16-Endothelial-stroma-proliferating_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

JCAD ADCY4 SYNPO PREX2 PCDH17

2.32e-051947858a4be91414a2e69dd410aa75791f16008204c9a1
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.32e-0519478532ba2cf9b8726bc3c6e9dc24b54d22ff188bb12b
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.32e-0519478553a5e8863d79a052dff0758f389be5ac3883c721
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD ADCY4 PREX2 RGS12 PCDH17

2.32e-0519478544c7d4b75f3b7c9301eba20610e548a01a84ae40
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 PREX1 PREX2 PCDH17

2.32e-05194785f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD ADCY4 PREX2 RGS12 PCDH17

2.32e-051947857f24023df47935286f185dd428d48797daf26f49
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Head_and_Neck_Carcinoma-Squamous_Cell_Carcinoma-8|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

TSHZ3 THBS2 THBS4 VCAN MEOX2

2.32e-0519478555b97095a7a17a312c616703d291738a0f806339
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 PREX1 PREX2 PCDH17

2.32e-05194785a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

JCAD ADCY4 SYNPO PREX2 PCDH17

2.37e-05195785a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCelldroplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY4 COMP PREX2 PCDH17 MEOX2

2.37e-051957854db30b3bc65c25626f828cd4f867f20c71809898
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial1_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.37e-051957853826bfafe85f8aa9a508202ceb2b02e81b090498
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

JCAD ADCY4 LNX1 PREX2 MEOX2

2.37e-0519578550a193475db1bb1e05b8590225a553688c372c14
ToppCellPND10-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

JCAD ADCY4 PREX2 RGS12 PCDH17

2.37e-05195785cd011433b3b9bfb1adb13eca2f3f2a5db024cd94
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS2 HTR2A COMP VCAN PENK

2.37e-0519578551db90e7611f7d69980878c046505ff34212079b
ToppCellPCW_13-14-Endothelial-Endothelial_mature|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.37e-0519578531353269591c9eee84872838e91995d4a035da46
ToppCellPCW_13-14-Endothelial|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.43e-051967857286de29a34e13834cd6347c67a1443897fa4ade
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating1_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.43e-05196785b826dce5b3daa8eb3d4a530b9564de58d9ce3767
ToppCellPCW_10-12-Endothelial-Endothelial_immature|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.43e-05196785c65b8c7ea34a21897c390e6fb42ee8ca41e9c976
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 PREX1 PREX2 PCDH17

2.43e-05196785ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 PREX1 PREX2 PCDH17

2.43e-0519678522767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellwk_08-11-Endothelial-Blood_vessel_endothelial-Early_cap|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.43e-051967850f00aac6dac699507ce336020b2e96fd192de0be
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 PREX1 PREX2 PCDH17

2.43e-05196785adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

JCAD ADCY4 SYNPO PREX2 PCDH17

2.43e-05196785b71b197cb92117dd9efaa13de000841901cc4ca8
ToppCellPCW_13-14-Endothelial-Endothelial_immature|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.43e-051967859ed96085f0acce07bf2f8d4cc212cc50e613be0c
ToppCellPCW_10-12-Endothelial|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.43e-051967852c60dcf9132ee156f25b349e2ac5313709def4f6
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 SYNPO PREX2 PCDH17

2.43e-05196785e224338490691d92c1f70b57112fabdcc92b06a9
ToppCellproximal-Endothelial-Capillary-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JCAD ADCY4 BRME1 PREX1 PCDH17

2.49e-05197785ddb8ea895f0f34d4f20a0740b708fa0f3e378801
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.49e-05197785a7922f65a8af4a773e4ce80114e4d895a594fa2f
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 SYNPO PREX2 PCDH17

2.49e-05197785c10dd1aaec01fb662eac83dfde90e3e426665d65
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.49e-051977854e9221cb02122aed2981c3c9157e847a3710e323
ToppCellPCW_13-14-Endothelial-Endothelial_immature-endo_immature3_(11)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.49e-0519778521a1080e1db3a64f3eccc7aed2b3189332d31038
ToppCellproximal-Endothelial-Capillary|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JCAD ADCY4 BRME1 PREX1 PCDH17

2.49e-0519778553baef54bd85c60ae24a3c163b3a3d937fb6ff0b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 PREX1 PREX2 PCDH17

2.49e-051977850f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-tip_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

JCAD ADCY4 PREX2 PCDH17 MEOX2

2.49e-05197785b212ff28ca2d1fea4140f186ab90941bdca21249
ToppCell(4)_Blood_vessel|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

JCAD ADCY4 PREX2 PCDH17 MEOX2

2.49e-051977851b82979a41ef46c814c82527a585900586d71260
ToppCell(4)_Endothelial_cells|World / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

JCAD ADCY4 PREX2 PCDH17 MEOX2

2.49e-05197785dd9abb43c23e7698433e455eacbf5b23b0a756c2
ToppCell(2)_Fibroblasts-(23)_Fibro-4|World / Cell class and subclass of bone marrow stroma cells in homeostatis

THBS2 THBS4 COMP VCAN MEOX2

2.49e-05197785a183919023a4aca90a06be0e5e89c817b38c5574
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

JCAD ADCY4 SYNPO PREX2 PCDH17

2.49e-051977852844dbcd0a673ed81c99920aa45858651a00736d
ToppCellproximal-3-Endothelial-Capillary|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

JCAD ADCY4 BRME1 PREX1 PCDH17

2.49e-05197785a1a61c03d67272693ec23e0d15f0a12bf618e2da
ToppCellMesenchymal_cells-Arteriolar_fibro.|Mesenchymal_cells / Lineage and Cell class

THBS2 THBS4 COMP PENK MEOX2

2.49e-05197785cb321836980e7b4efbb9284c6af7ccd34079d2be
ToppCellPCW_13-14-Endothelial-Endothelial_cycling-endo_proliferating3_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

JCAD ADCY4 TNFRSF10A PREX1 PCDH17

2.49e-05197785aedc1e3ed6b558bf2f7649919f43049f8348ab85
Diseaseinfertility (implicated_via_orthology)

GCM2 BRCA2

1.33e-047752DOID:5223 (implicated_via_orthology)
Diseaseupper aerodigestive tract neoplasm

BRCA2 EIF4G2 LNX1 PCDH17 IWS1

4.15e-04246755EFO_0004284
Diseasehead and neck squamous cell carcinoma (is_implicated_in)

ING1 TNFRSF10A

6.55e-0415752DOID:5520 (is_implicated_in)
Diseaseanthranilic acid measurement

MYO3B LNX1

7.48e-0416752EFO_0010460
Diseasewellbeing measurement, alcohol consumption measurement

PARG PCDH10 PREX2

8.98e-0474753EFO_0007869, EFO_0007878
Diseaseborna disease (biomarker_via_orthology)

IL16 PARG

9.50e-0418752DOID:5154 (biomarker_via_orthology)
DiseaseFEV/FEC ratio

JCAD TSHZ3 ANKS1B PJA1 RREB1 ARFIP1 LNX1 AAGAB PCDH10 IKZF4

1.07e-0312287510EFO_0004713
Diseasesystemising measurement

CEP170 TSHZ3

1.30e-0321752EFO_0010221

Protein segments in the cluster

PeptideGeneStartEntry
NKHDDGTQSDSENAG

CEP170

371

Q5SW79
HDSNDESNDDSTQVQ

VCAN

2606

P13611
AADLANRSGESNTHQ

CLPX

456

O76031
DSDQDQDGDGHQDSR

COMP

431

P49747
QHSEEASKDNSDGVN

HTR2A

451

P28223
TSNGEVDDSREHSFN

ARFIP1

16

P53367
ETERSNDSGNGEHKS

BIVM

6

Q86UB2
AKAHLSSDDSNSNGD

AKAP11

801

Q9UKA4
SGQDAQQDAERSCSH

ADCY4

941

Q8NFM4
HQQSHQESARDRSGE

FLG

771

P20930
RDNSRHSASQDGQDT

FLG

826

P20930
EQARNSSRHSASQDG

FLG

1471

P20930
QARDSSRHSASQEGQ

FLG

1796

P20930
QTRNDEQSGDGSRHS

FLG

2516

P20930
QASDNEGHSEDSDTQ

FLG

2691

P20930
QDSSRHSASQDGQDT

FLG

2771

P20930
ASDNEGHSEDSDTQS

FLG

3016

P20930
EQARDSSRHSASQEG

FLG

3416

P20930
QARDSSRHSASQEGQ

FLG

3741

P20930
DHGNQRQEAANESNT

CCDC140

21

Q96MF4
HNSEGADNSRDDSSS

AFF4

416

Q9UHB7
GHGDSDQADSDQDTN

PCDH17

891

O14917
SDSENEDVNQHGSDS

IWS1

106

Q96ST2
NRERSHHQDGSDNEE

PENK

166

P01210
GTNHTDDLSRQDDND

ANKS1B

581

Q7Z6G8
GSDNHSERSDNRSEA

LEO1

76

Q8WVC0
NRSEASERSDHEDND

LEO1

86

Q8WVC0
SGNAENRERHSESSD

MAGI3

251

Q5TCQ9
RQHGDDASEEKAANQ

IP6K2

226

Q9UHH9
GSEKDDDSFNLHNSN

GPBP1

321

Q86WP2
QGSRHDSEQDNSDNN

FUS

271

P35637
HQQSRGGADSSDSQD

JCAD

301

Q9P266
ANYESTGDNHDRDLS

GAPVD1

1051

Q14C86
HSDTDSEENRDNQQF

PARG

196

Q86W56
SHDQSGDSLNSDEGD

KAT14

51

Q9H8E8
AHADAGTQTNGDLED

FAM153A

101

Q9UHL3
EDDDGDHSSLQSGQS

IL16

1066

Q14005
NSGDQDSRSGHNEAK

MYLK4

41

Q86YV6
SGSAVANHADQGREN

LNX1

236

Q8TBB1
ANHADQGRENSENTT

LNX1

241

Q8TBB1
QQTGDSIANEDSHDS

MEOX2

281

P50222
SEQGDSDHDATNRAQ

PCDH10

916

Q9P2E7
NSAANNSANEKERHD

EIF4G2

61

P78344
GSHRDNNRSEAEANT

OTUD3

371

Q5T2D3
RASQDHLSEQGADDS

BRME1

206

Q0VDD7
TDSENTNQREAASHG

BRCA2

251

P51587
AASRNSHNLEFDGSD

BRCA2

1326

P51587
QDSQDGHNSSEDASA

REXO1L1P

631

Q8IX06
EGHPRNSNSNSDSDE

CTR9

1031

Q6PD62
SNNEASDRGSEHGSD

CTR9

1156

Q6PD62
SQHASRGGQSDDDED

GBF1

1466

Q92538
LEGTEHRQDNDTGNE

DDX10

566

Q13206
GNEAVASRDLSENND

GOLM1

181

Q8NBJ4
NSGHDSTDTDSNHEE

IKZF3

381

Q9UKT9
RSQGTDNHREEAADN

CCDC8

376

Q9H0W5
HADRNNSDDNHLASE

CEP295

1796

Q9C0D2
HENDQSSADGASERA

RUBCN

106

Q92622
NGCQDSTDTESNHED

IKZF4

451

Q9H2S9
DEDEEGATALNNHSS

MEA1

116

Q16626
DHSDNESTSSENSGR

UTY

1006

O14607
SSESHQEAASNENDK

PPP4R1

411

Q8TF05
SREEQGASQHDDRAS

SYNPO

91

Q8N3V7
GSAASGNNHRDDVTA

TAF1L

1156

Q8IZX4
AGSAASGNNHRDDDT

TAF1

1136

P21675
SGNNHRDDDTASVTS

TAF1

1141

P21675
NRENASSNHDHDDGA

ING1

301

Q9UK53
RESEAEENQDSSGHF

GCM2

191

O75603
THEDAQEARASQEAS

PREX1

791

Q8TCU6
INENHESSAAADDNT

SLC12A1

26

Q13621
DHRGGASNTTDAQVD

AAGAB

221

Q6PD74
DTNQDSDGDGHQDST

THBS4

626

P35443
NESADDHETTDNNES

TSPYL2

496

Q9H2G4
DHETTDNNESADDNN

TSPYL2

501

Q9H2G4
SHGNNQDSSDSDNEA

TSPYL2

551

Q9H2G4
LDGDADAHQNNSTSS

RGS12

406

O14924
GEEDSENESTHSGNN

RREB1

1581

Q92766
HSGNNAVSENEAELA

RREB1

1591

Q92766
QDLENAASGDAAVHQ

RPRD1A

171

Q96P16
ATDLQGNDFDNDRNH

SSX9P

76

Q7RTT3
GAQHDSSGSLNENSE

UBTD2

6

Q8WUN7
DQHSQSGSSSDNTER

YAF2

146

Q8IY57
GDEQEDSGHDTISNR

PREX2

1091

Q70Z35
EASNATHGNSNIDAA

TTLL2

426

Q9BWV7
AEDNAHNEILSNADS

TNFRSF10A

291

O00220
TGHYRDDNHETDNNN

TSHZ3

236

Q63HK5
EENTNSDHESEQLGS

ZC3H12C

91

Q9C0D7
NANQADHDRDGQGDA

THBS2

881

P35442
EQSPNDAHRGAESEN

ZNF629

16

Q9UEG4
RDTANDNEGHSDGLA

PJA1

291

Q8NG27
SNGQLGNHSEEDSTD

USP6

1286

P35125
HETTGDAQCSQNEND

ZBBX

346

A8MT70
ETESDSESNHSNQDN

UBR5

1621

O95071
SESNHSNQDNASGRR

UBR5

1626

O95071
SNRRNESAAHNQAGD

MYO3B

1111

Q8WXR4
QSYSHNSDDLSREGN

MYO9A

1651

B2RTY4
AQDDSGAQDSQQHNS

MYOT

201

Q9UBF9