Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

TRPM4 SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC41A3 SLC34A1 GRIK4 GRIK5 SLC6A14

1.81e-091718110GO:0015081
GeneOntologyMolecularFunctiontransmembrane transporter activity

TRPM4 SLC6A12 SLC6A13 SLC9A3 PIEZO2 ATP8A1 SLC13A1 SLC41A3 CLCA2 SLC34A1 ABCA13 ATP6V0A4 SLC37A2 GRIA4 MFSD8 GRIK4 GRIK5 SLC2A2 SLC2A5 SLC6A14 OPRM1

6.04e-0911808121GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

TRPM4 SLC6A12 SLC6A13 SLC9A3 PIEZO2 ATP8A1 SLC13A1 SLC41A3 CLCA2 SLC34A1 ATP6V0A4 GRIA4 MFSD8 GRIK4 GRIK5 SLC6A14 OPRM1

1.52e-087938117GO:0015075
GeneOntologyMolecularFunctiontransporter activity

TRPM4 SLC6A12 SLC6A13 SLC9A3 PIEZO2 ATP8A1 SLC13A1 SLC41A3 CLCA2 SLC34A1 ABCA13 ATP6V0A4 SLC37A2 GRIA4 MFSD8 GRIK4 GRIK5 SLC2A2 SLC2A5 SLC6A14 OPRM1

2.82e-0812898121GO:0005215
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

TRPM4 SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC41A3 CLCA2 SLC34A1 ATP6V0A4 SLC37A2 GRIA4 MFSD8 GRIK4 GRIK5 SLC6A14 OPRM1

5.32e-087588116GO:0015318
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

TRPM4 SLC6A12 SLC6A13 SLC9A3 PIEZO2 ATP8A1 SLC13A1 SLC41A3 SLC34A1 ATP6V0A4 GRIK4 GRIK5 SLC6A14 OPRM1

4.11e-076648114GO:0008324
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

TRPM4 SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC41A3 SLC34A1 ATP6V0A4 GRIA4 GRIK4 GRIK5 SLC6A14 OPRM1

1.35e-066278113GO:0022890
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

ADORA1 OR8I2 ADORA3 MS4A2 HTR4 PTPRO GPR85 C5AR2 GPR143 ADGRG1 GRIA4 GRIK4 GRIK5 FCRL5 OR51V1 F2RL1 OR51B4 LEPR OPRM1

1.44e-0613538119GO:0004888
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

TRPM4 SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC41A3 SLC34A1 GRIK4 GRIK5 SLC6A14 OPRM1

2.71e-064658111GO:0046873
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC6A12 SLC6A13 SLC9A3 ATP8A1 SLC13A1 SLC41A3 SLC34A1 ABCA13 ATP6V0A4 SLC37A2 SLC6A14

3.46e-064778111GO:0022804
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC6A12 SLC6A13 SLC9A3 ATP8A1 SLC13A1 SLC41A3 SLC34A1 ATP6V0A4 SLC6A14

3.60e-06301819GO:0022853
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC6A12 SLC6A13 GRIA4 GRIK4 GRIK5 SLC6A14

4.32e-06105816GO:0015171
GeneOntologyMolecularFunctioninorganic anion transmembrane transporter activity

SLC6A12 SLC6A13 SLC13A1 CLCA2 SLC34A1 SLC37A2 MFSD8

6.10e-06171817GO:0015103
GeneOntologyMolecularFunctionsolute:sodium symporter activity

SLC6A12 SLC6A13 SLC13A1 SLC34A1 SLC6A14

1.95e-0581815GO:0015370
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC6A12 SLC6A13 SLC37A2 GRIA4 GRIK4 GRIK5 SLC2A2 SLC6A14

2.48e-05293818GO:0008514
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC41A3 SLC34A1 SLC37A2 SLC6A14

2.67e-05296818GO:0015291
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIA4 GRIK4 GRIK5

4.20e-0517813GO:0004970
GeneOntologyMolecularFunctionmonoatomic anion:sodium symporter activity

SLC6A12 SLC6A13 SLC13A1

5.95e-0519813GO:0015373
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A12 SLC6A13 SLC6A14

1.07e-0423813GO:0005283
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

GRIA4 GRIK4 GRIK5

1.22e-0424813GO:0099507
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A12 SLC6A13 SLC13A1 SLC34A1 SLC6A14

1.23e-04119815GO:0015294
GeneOntologyMolecularFunctionmonoatomic anion:monoatomic cation symporter activity

SLC6A12 SLC6A13 SLC13A1

1.56e-0426813GO:0015296
GeneOntologyMolecularFunctionglutamate receptor activity

GRIA4 GRIK4 GRIK5

1.75e-0427813GO:0008066
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC6A12 SLC6A13 GRIA4 GRIK4 GRIK5 SLC6A14

1.96e-04207816GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC6A12 SLC6A13 GRIA4 GRIK4 GRIK5 SLC6A14

2.01e-04208816GO:0005342
GeneOntologyMolecularFunctionamino acid:monoatomic cation symporter activity

SLC6A12 SLC6A13 SLC6A14

2.18e-0429813GO:0005416
GeneOntologyMolecularFunctionG protein-coupled receptor activity

ADORA1 OR8I2 ADORA3 HTR4 GPR85 C5AR2 GPR143 ADGRG1 OR51V1 F2RL1 OR51B4 OPRM1

2.23e-048848112GO:0004930
GeneOntologyMolecularFunctionkainate selective glutamate receptor activity

GRIK4 GRIK5

2.41e-046812GO:0015277
GeneOntologyMolecularFunctiongamma-aminobutyric acid:sodium:chloride symporter activity

SLC6A12 SLC6A13

2.41e-046812GO:0005332
GeneOntologyMolecularFunctionG protein-coupled adenosine receptor activity

ADORA1 ADORA3

3.37e-047812GO:0001609
GeneOntologyMolecularFunctionsymporter activity

SLC6A12 SLC6A13 SLC13A1 SLC34A1 SLC6A14

3.62e-04150815GO:0015293
GeneOntologyMolecularFunctionmonoatomic anion transmembrane transporter activity

SLC6A12 SLC6A13 SLC13A1 CLCA2 MFSD8

3.73e-04151815GO:0008509
GeneOntologyMolecularFunctionorganic acid:sodium symporter activity

SLC6A12 SLC6A13 SLC6A14

3.83e-0435813GO:0005343
GeneOntologyMolecularFunctiongated channel activity

TRPM4 PIEZO2 CLCA2 GRIA4 GRIK4 GRIK5 OPRM1

4.15e-04334817GO:0022836
GeneOntologyMolecularFunctionmonoatomic ion channel activity

TRPM4 PIEZO2 CLCA2 GRIA4 MFSD8 GRIK4 GRIK5 OPRM1

5.44e-04459818GO:0005216
GeneOntologyMolecularFunctionfructose transmembrane transporter activity

SLC2A2 SLC2A5

5.74e-049812GO:0005353
GeneOntologyMolecularFunctiongamma-aminobutyric acid transmembrane transporter activity

SLC6A12 SLC6A13

5.74e-049812GO:0015185
GeneOntologyMolecularFunctionheterotrimeric G-protein binding

ADORA1 F2RL1

5.74e-049812GO:0032795
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

RGS22 F2RL1 OPRM1

7.06e-0443813GO:0001965
GeneOntologyMolecularFunctionneurotransmitter receptor activity

HTR4 GRIA4 GRIK4 GRIK5

7.33e-04100814GO:0030594
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

TRPM4 CLCA2 GRIA4 GRIK4 GRIK5

1.13e-03193815GO:0015276
GeneOntologyMolecularFunctionsodium channel activity

TRPM4 GRIK4 GRIK5

1.23e-0352813GO:0005272
GeneOntologyMolecularFunctionligand-gated channel activity

TRPM4 CLCA2 GRIA4 GRIK4 GRIK5

1.24e-03197815GO:0022834
GeneOntologyMolecularFunctionchannel activity

TRPM4 PIEZO2 CLCA2 GRIA4 MFSD8 GRIK4 GRIK5 OPRM1

1.30e-03525818GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

TRPM4 PIEZO2 CLCA2 GRIA4 MFSD8 GRIK4 GRIK5 OPRM1

1.31e-03526818GO:0022803
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential

GRIA4 GRIK4 GRIK5

1.61e-0357813GO:1904315
GeneOntologyMolecularFunctionmonocarboxylate:sodium symporter activity

SLC6A12 SLC6A13

1.65e-0315812GO:0140161
GeneOntologyMolecularFunctionchloride transmembrane transporter activity

SLC6A12 SLC6A13 CLCA2 MFSD8

1.68e-03125814GO:0015108
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GRIA4 GRIK4 GRIK5

1.86e-0360813GO:0099529
GeneOntologyMolecularFunctionsodium:chloride symporter activity

SLC6A12 SLC6A13

2.12e-0317812GO:0015378
GeneOntologyMolecularFunctiontransmitter-gated channel activity

GRIA4 GRIK4 GRIK5

2.34e-0365813GO:0022835
GeneOntologyMolecularFunctiontransmitter-gated monoatomic ion channel activity

GRIA4 GRIK4 GRIK5

2.34e-0365813GO:0022824
GeneOntologyMolecularFunctionligand-gated sodium channel activity

GRIK4 GRIK5

2.38e-0318812GO:0015280
GeneOntologyMolecularFunctionsecondary active monocarboxylate transmembrane transporter activity

SLC6A12 SLC6A13

2.66e-0319812GO:0015355
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GRIA4 GRIK4 GRIK5

3.52e-0375813GO:0098960
GeneOntologyMolecularFunctionextracellular ligand-gated monoatomic ion channel activity

GRIA4 GRIK4 GRIK5

3.79e-0377813GO:0005230
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A12 SLC6A13

3.89e-0323812GO:0015377
GeneOntologyMolecularFunctionphosphate transmembrane transporter activity

SLC34A1 SLC37A2

4.23e-0324812GO:0005315
GeneOntologyMolecularFunctionhexose transmembrane transporter activity

SLC2A2 SLC2A5

4.59e-0325812GO:0015149
GeneOntologyMolecularFunctionG-protein beta-subunit binding

F2RL1 OPRM1

4.59e-0325812GO:0031681
GeneOntologyMolecularFunctionD-glucose transmembrane transporter activity

SLC2A2 SLC2A5

4.59e-0325812GO:0055056
GeneOntologyMolecularFunctionmonosaccharide transmembrane transporter activity

SLC2A2 SLC2A5

5.34e-0327812GO:0015145
GeneOntologyMolecularFunctionsugar transmembrane transporter activity

SLC2A2 SLC2A5

6.15e-0329812GO:0051119
GeneOntologyMolecularFunctionmodified amino acid transmembrane transporter activity

SLC6A13 SLC6A14

7.91e-0333812GO:0072349
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

TRPM4 SLC6A12 SLC6A13 SLC9A3 PIEZO2 ATP8A1 FMR1 MS4A2 SLC13A1 TMEM168 SLC41A3 CLCA2 SLC34A1 ATP6V0A4 GRIA4 MFSD8 GRIK4 GRIK5 FCRL5 SLC6A14 OPRM1

1.24e-0911158121GO:0034220
GeneOntologyBiologicalProcessmonoatomic ion transport

ADORA1 TRPM4 SLC6A12 SLC6A13 SLC9A3 PIEZO2 ATP8A1 FMR1 MS4A2 SLC13A1 TMEM168 SLC41A3 CLCA2 SLC34A1 ATP6V0A4 GRIA4 MFSD8 GRIK4 GRIK5 FCRL5 SLC6A14 OPRM1

9.21e-0913748122GO:0006811
GeneOntologyBiologicalProcesssodium ion transmembrane transport

TRPM4 SLC6A12 SLC6A13 SLC9A3 SLC13A1 TMEM168 SLC41A3 SLC34A1 SLC6A14

1.26e-07208819GO:0035725
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

TRPM4 SLC6A12 SLC6A13 SLC9A3 FMR1 MS4A2 SLC13A1 TMEM168 SLC41A3 CLCA2 SLC34A1 ATP6V0A4 SLC37A2 MFSD8 FCRL5 SLC6A14 OPRM1

3.42e-0710178117GO:0098660
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

TRPM4 SLC6A12 SLC6A13 SLC9A3 PIEZO2 ATP8A1 FMR1 MS4A2 SLC13A1 TMEM168 SLC41A3 SLC34A1 ATP6V0A4 FCRL5 SLC6A14 OPRM1

6.50e-079428116GO:0098655
GeneOntologyBiologicalProcessimport into cell

ADORA1 GPM6B ACE2 TRPM4 SLC6A12 SLC6A13 SLC9A3 ATP8A1 FMR1 SLC34A1 ABCA13 ITSN1 F2RL1 LRP1B LEPR SLC2A5 SLC6A14

7.31e-0710748117GO:0098657
GeneOntologyBiologicalProcesssodium ion transport

TRPM4 SLC6A12 SLC6A13 SLC9A3 SLC13A1 TMEM168 SLC41A3 SLC34A1 SLC6A14

1.32e-06275819GO:0006814
GeneOntologyBiologicalProcessmonoatomic cation transport

ADORA1 TRPM4 SLC6A12 SLC6A13 SLC9A3 PIEZO2 ATP8A1 FMR1 MS4A2 SLC13A1 TMEM168 SLC41A3 SLC34A1 ATP6V0A4 FCRL5 SLC6A14 OPRM1

2.03e-0611578117GO:0006812
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

TRPM4 SLC6A12 SLC6A13 SLC9A3 FMR1 MS4A2 SLC13A1 TMEM168 SLC41A3 SLC34A1 ATP6V0A4 FCRL5 SLC6A14 OPRM1

1.29e-059228114GO:0098662
GeneOntologyBiologicalProcessG protein-coupled purinergic receptor signaling pathway

ADORA1 ADORA3 ACP3

1.62e-0513813GO:0035588
GeneOntologyBiologicalProcessG protein-coupled adenosine receptor signaling pathway

ADORA1 ADORA3 ACP3

1.62e-0513813GO:0001973
GeneOntologyBiologicalProcessregulation of glomerular filtration

ADORA1 PTPRO F2RL1

1.62e-0513813GO:0003093
GeneOntologyBiologicalProcesscirculatory system process

ADORA1 ACE2 TRPM4 SLC6A13 ADORA3 ATP8A1 ERAP1 PTPRO EXT2 F2RL1 LEPR SLC2A5

2.77e-057338112GO:0003013
GeneOntologyBiologicalProcessmetal ion transport

ADORA1 TRPM4 SLC6A12 SLC6A13 SLC9A3 FMR1 MS4A2 SLC13A1 TMEM168 SLC41A3 SLC34A1 FCRL5 SLC6A14 OPRM1

3.17e-0510008114GO:0030001
GeneOntologyBiologicalProcessimport across plasma membrane

ACE2 TRPM4 SLC6A13 SLC9A3 SLC34A1 SLC2A5 SLC6A14

3.38e-05230817GO:0098739
GeneOntologyBiologicalProcessregulation of blood pressure

ADORA1 ACE2 ERAP1 PTPRO EXT2 F2RL1 SLC2A5

4.09e-05237817GO:0008217
GeneOntologyBiologicalProcesscarbohydrate metabolic process

CHIA OGDHL ST8SIA5 MFSD8 EXT2 EDEM1 LEPR SLC2A2 SLC2A5 CRTC2 OPRM1

4.33e-056468111GO:0005975
GeneOntologyBiologicalProcessnegative regulation of long-term synaptic depression

ADORA1 FMR1

4.56e-053812GO:1900453
GeneOntologyBiologicalProcessrenal system process involved in regulation of blood volume

ADORA1 PTPRO F2RL1

4.56e-0518813GO:0001977
GeneOntologyBiologicalProcessvascular process in circulatory system

ADORA1 ACE2 TRPM4 SLC6A13 ATP8A1 EXT2 F2RL1 LEPR

6.16e-05344818GO:0003018
GeneOntologyBiologicalProcesspositive regulation of transport

ADORA1 ACE2 TRPM4 ADORA3 ATP8A1 FMR1 MS4A2 SLC34A1 ABCA13 ITSN1 EDEM1 F2RL1 LEPR SLC2A2

7.37e-0510818114GO:0051050
GeneOntologyBiologicalProcessinorganic anion transport

SLC13A1 CLCA2 SLC34A1 SLC37A2 MFSD8 SLC6A14

7.67e-05180816GO:0015698
GeneOntologyBiologicalProcessglutamate receptor signaling pathway

FMR1 GRIA4 GRIK4 GRIK5

8.52e-0559814GO:0007215
GeneOntologyBiologicalProcessgamma-aminobutyric acid reuptake

SLC6A12 SLC6A13

9.09e-054812GO:0051936
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure

ADORA1 ACE2 PTPRO F2RL1 SLC2A5

1.29e-04124815GO:0003073
GeneOntologyBiologicalProcesssodium ion import across plasma membrane

TRPM4 SLC9A3 SLC34A1

1.59e-0427813GO:0098719
GeneOntologyBiologicalProcessionotropic glutamate receptor signaling pathway

GRIA4 GRIK4 GRIK5

1.59e-0427813GO:0035235
GeneOntologyBiologicalProcessmucus secretion

ADORA1 ADORA3 HTR4

1.59e-0427813GO:0070254
GeneOntologyBiologicalProcessregulation of renal system process

ADORA1 PTPRO F2RL1

1.78e-0428813GO:0098801
GeneOntologyBiologicalProcessinorganic anion transmembrane transport

SLC13A1 CLCA2 SLC34A1 SLC37A2 MFSD8

1.85e-04134815GO:0098661
GeneOntologyBiologicalProcesssignal release

ADORA1 TRPM4 ADORA3 FMR1 ITSN1 GRIK5 F2RL1 LEPR SLC2A2 OPRM1

2.34e-046538110GO:0023061
GeneOntologyBiologicalProcessrenal system process involved in regulation of systemic arterial blood pressure

ADORA1 PTPRO F2RL1

2.42e-0431813GO:0003071
GeneOntologyBiologicalProcesshormone secretion

ADORA1 TRPM4 ADORA3 ITSN1 F2RL1 LEPR SLC2A2 OPRM1

2.43e-04420818GO:0046879
GeneOntologyBiologicalProcessregulation of presynaptic membrane potential

GRIA4 GRIK4 GRIK5

2.67e-0432813GO:0099505
GeneOntologyBiologicalProcesscarbohydrate derivative catabolic process

UPB1 CHIA PGLYRP1 ENTPD5 OGDHL MFSD8 EDEM1

2.79e-04323817GO:1901136
GeneOntologyBiologicalProcesspurinergic nucleotide receptor signaling pathway

ADORA1 ADORA3 ACP3

2.92e-0433813GO:0035590
GeneOntologyBiologicalProcessglomerular filtration

ADORA1 PTPRO F2RL1

2.92e-0433813GO:0003094
GeneOntologyBiologicalProcesshormone transport

ADORA1 TRPM4 ADORA3 ITSN1 F2RL1 LEPR SLC2A2 OPRM1

2.94e-04432818GO:0009914
GeneOntologyBiologicalProcesspositive regulation of secretion

ADORA1 TRPM4 ADORA3 MS4A2 ITSN1 F2RL1 LEPR SLC2A2

3.08e-04435818GO:0051047
GeneOntologyBiologicalProcessregulation of membrane potential

ADORA1 TRPM4 PIEZO2 FMR1 SLC34A1 GRIA4 GRIK4 GRIK5 OPRM1

3.41e-04559819GO:0042391
GeneOntologyBiologicalProcessrenal filtration

ADORA1 PTPRO F2RL1

3.79e-0436813GO:0097205
GeneOntologyBiologicalProcesspositive regulation of peptide secretion

ADORA1 TRPM4 ITSN1 LEPR SLC2A2

4.33e-04161815GO:0002793
GeneOntologyBiologicalProcessneurotransmitter reuptake

GPM6B SLC6A12 SLC6A13

4.46e-0438813GO:0098810
GeneOntologyBiologicalProcesspositive regulation of leukocyte degranulation

ADORA3 MS4A2 F2RL1

4.46e-0438813GO:0043302
GeneOntologyBiologicalProcessregulation of hormone secretion

ADORA1 TRPM4 ITSN1 F2RL1 LEPR SLC2A2 OPRM1

4.92e-04355817GO:0046883
GeneOntologyBiologicalProcessligand-gated ion channel signaling pathway

GRIA4 GRIK4 GRIK5

5.19e-0440813GO:1990806
GeneOntologyBiologicalProcesssynaptic vesicle cycle

ATP8A1 FMR1 ABCA13 ITSN1 ATP6V0A4 GRIK5

6.04e-04264816GO:0099504
GeneOntologyBiologicalProcessregulation of secretion by cell

ADORA1 TRPM4 ADORA3 FMR1 MS4A2 ITSN1 F2RL1 LEPR SLC2A2 OPRM1

6.27e-047408110GO:1903530
GeneOntologyBiologicalProcessfructose transmembrane transport

SLC2A2 SLC2A5

6.72e-0410812GO:0015755
GeneOntologyBiologicalProcessamino acid neurotransmitter reuptake

SLC6A12 SLC6A13

6.72e-0410812GO:0051933
GeneOntologyBiologicalProcessmodified amino acid transport

SLC6A12 SLC6A13 SLC6A14

6.88e-0444813GO:0072337
GeneOntologyBiologicalProcessregulation of postsynaptic membrane potential

ADORA1 GRIA4 GRIK4 GRIK5 OPRM1

7.18e-04180815GO:0060078
GeneOntologyBiologicalProcesspyrimidine ribonucleotide catabolic process

UPB1 ENTPD5

8.19e-0411812GO:0009222
GeneOntologyBiologicalProcessregulation of peptide transport

ADORA1 TRPM4 ITSN1 F2RL1 LEPR SLC2A2

8.52e-04282816GO:0090087
GeneOntologyBiologicalProcessregulation of peptide secretion

ADORA1 TRPM4 ITSN1 F2RL1 LEPR SLC2A2

8.52e-04282816GO:0002791
GeneOntologyBiologicalProcesscarbohydrate derivative metabolic process

UPB1 CHIA PGLYRP1 SLC34A1 ACP3 ENTPD5 OGDHL SLC37A2 ST8SIA5 MFSD8 EXT2 GALNT5 EDEM1

9.32e-0412268113GO:1901135
GeneOntologyBiologicalProcessblood circulation

ADORA1 ACE2 TRPM4 ADORA3 ERAP1 PTPRO EXT2 F2RL1 SLC2A5

9.81e-04648819GO:0008015
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

ADORA1 OR8I2 ADORA3 MS4A2 HTR4 ACP3 GPR85 C5AR2 GPR143 ADGRG1 OR51V1 F2RL1 OR51B4 OPRM1

9.94e-0413958114GO:0007186
GeneOntologyBiologicalProcessamino acid transport

ADORA1 ACE2 SLC6A12 SLC6A13 SLC6A14

1.03e-03195815GO:0006865
GeneOntologyBiologicalProcesspositive regulation of secretion by cell

TRPM4 ADORA3 MS4A2 ITSN1 F2RL1 LEPR SLC2A2

1.05e-03404817GO:1903532
GeneOntologyBiologicalProcesspositive regulation of insulin secretion involved in cellular response to glucose stimulus

TRPM4 LEPR SLC2A2

1.06e-0351813GO:0035774
GeneOntologyBiologicalProcessneurotransmitter uptake

GPM6B SLC6A12 SLC6A13

1.12e-0352813GO:0001504
GeneOntologyBiologicalProcessregulation of secretion

ADORA1 TRPM4 ADORA3 FMR1 MS4A2 ITSN1 F2RL1 LEPR SLC2A2 OPRM1

1.15e-038018110GO:0051046
GeneOntologyBiologicalProcessaromatic amino acid transport

ACE2 SLC6A14

1.16e-0313812GO:0015801
GeneOntologyBiologicalProcessregulation of tube diameter

ADORA1 ACE2 TRPM4 EXT2 F2RL1

1.20e-03202815GO:0035296
GeneOntologyBiologicalProcessblood vessel diameter maintenance

ADORA1 ACE2 TRPM4 EXT2 F2RL1

1.20e-03202815GO:0097746
GeneOntologyBiologicalProcessregulation of tube size

ADORA1 ACE2 TRPM4 EXT2 F2RL1

1.23e-03203815GO:0035150
GeneOntologyBiologicalProcessamino acid transmembrane transport

ACE2 SLC6A12 SLC6A13 SLC6A14

1.28e-03120814GO:0003333
GeneOntologyBiologicalProcessamide transport

ADORA1 TRPM4 ABCA13 ITSN1 F2RL1 LEPR SLC2A2

1.32e-03420817GO:0042886
GeneOntologyBiologicalProcessamino-acid betaine transport

SLC6A12 SLC6A14

1.34e-0314812GO:0015838
GeneOntologyBiologicalProcessregulation of hormone levels

ADORA1 ACE2 TRPM4 ADORA3 ITSN1 F2RL1 LEPR SLC2A2 OPRM1

1.43e-03684819GO:0010817
GeneOntologyBiologicalProcessendocytosis

ADORA1 ACE2 SLC9A3 ATP8A1 FMR1 ABCA13 ITSN1 F2RL1 LRP1B LEPR

1.46e-038278110GO:0006897
GeneOntologyBiologicalProcessglycoprotein metabolic process

SLC34A1 ENTPD5 ST8SIA5 MFSD8 EXT2 GALNT5 EDEM1

1.50e-03430817GO:0009100
GeneOntologyBiologicalProcessamino acid import across plasma membrane

ACE2 SLC6A13 SLC6A14

1.54e-0358813GO:0089718
GeneOntologyBiologicalProcessphosphate ion transmembrane transport

SLC34A1 SLC37A2

1.55e-0315812GO:0035435
GeneOntologyBiologicalProcessvesicle-mediated transport in synapse

ATP8A1 FMR1 ABCA13 ITSN1 ATP6V0A4 GRIK5

1.65e-03321816GO:0099003
GeneOntologyBiologicalProcessnegative regulation of circadian rhythm

ADORA1 LEPR

1.76e-0316812GO:0042754
GeneOntologyBiologicalProcessregulation of mucus secretion

ADORA1 ADORA3

1.76e-0316812GO:0070255
GeneOntologyBiologicalProcessregulation of systemic arterial blood pressure mediated by a chemical signal

ACE2 F2RL1 SLC2A5

1.78e-0361813GO:0003044
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

ADORA1 GRIA4 GRIK4 GRIK5

1.82e-03132814GO:0035249
GeneOntologyBiologicalProcessaminoglycan metabolic process

CHIA PGLYRP1 EXT2 GALNT5

1.82e-03132814GO:0006022
GeneOntologyCellularComponentbrush border membrane

ACE2 SLC9A3 SLC34A1 ATP6V0A4 SLC2A2 SLC6A14

8.35e-0783816GO:0031526
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIA4 GRIK4 GRIK5

1.11e-066813GO:0032983
GeneOntologyCellularComponentapical part of cell

ACE2 SLC9A3 SLC13A1 PTPRO SLC34A1 ACP3 ATP6V0A4 C5AR2 GPR143 SLC2A2 SLC2A5 SLC6A14

2.84e-065928112GO:0045177
GeneOntologyCellularComponentsodium channel complex

TRPM4 GRIA4 GRIK4 GRIK5

4.61e-0629814GO:0034706
GeneOntologyCellularComponentbasal plasma membrane

ADORA1 SLC6A12 SLC6A13 CLCA2 SLC34A1 ATP6V0A4 C5AR2 LEPR SLC2A2

9.24e-06354819GO:0009925
GeneOntologyCellularComponentpresynaptic membrane

ADORA1 ADORA3 FMR1 ITSN1 GRIA4 GRIK4 GRIK5 OPRM1

1.20e-05277818GO:0042734
GeneOntologyCellularComponentsynaptic membrane

ADORA1 ADORA3 FMR1 PTPRO ITSN1 GRIA4 NBEA GRIK4 GRIK5 TENM2 OPRM1

1.50e-055838111GO:0097060
GeneOntologyCellularComponentbasal part of cell

ADORA1 SLC6A12 SLC6A13 CLCA2 SLC34A1 ATP6V0A4 C5AR2 LEPR SLC2A2

1.56e-05378819GO:0045178
GeneOntologyCellularComponentapical plasma membrane

ACE2 SLC9A3 SLC13A1 PTPRO SLC34A1 ATP6V0A4 GPR143 SLC2A2 SLC2A5 SLC6A14

1.84e-054878110GO:0016324
GeneOntologyCellularComponentpostsynaptic membrane

ADORA1 FMR1 PTPRO GRIA4 NBEA GRIK4 GRIK5 TENM2 OPRM1

2.68e-05405819GO:0045211
GeneOntologyCellularComponentbrush border

ACE2 SLC9A3 SLC34A1 ATP6V0A4 SLC2A2 SLC6A14

2.77e-05152816GO:0005903
GeneOntologyCellularComponentterminal bouton

ADORA1 FMR1 GRIA4 GRIK4 GRIK5

3.58e-0596815GO:0043195
GeneOntologyCellularComponentdendritic spine

ADORA1 FMR1 PTPRO ITSN1 GRIA4 TENM2 OPRM1

4.29e-05242817GO:0043197
GeneOntologyCellularComponentneuron spine

ADORA1 FMR1 PTPRO ITSN1 GRIA4 TENM2 OPRM1

4.88e-05247817GO:0044309
GeneOntologyCellularComponentglutamatergic synapse

ATP8A1 FMR1 HTR4 PTPRO ITSN1 ELAVL2 ELAVL1 GRIA4 NBEA GRIK4 GRIK5 TENM2

6.95e-058178112GO:0098978
GeneOntologyCellularComponentpresynapse

ADORA1 SLC6A12 SLC6A13 ADORA3 ATP8A1 FMR1 ITSN1 ATP6V0A4 GRIA4 GRIK4 GRIK5 OPRM1

1.49e-048868112GO:0098793
GeneOntologyCellularComponentaxon terminus

ADORA1 FMR1 ITSN1 GRIA4 GRIK4 GRIK5

1.66e-04210816GO:0043679
GeneOntologyCellularComponentcluster of actin-based cell projections

ACE2 SLC9A3 SLC34A1 ATP6V0A4 SLC2A2 SLC6A14

2.30e-04223816GO:0098862
GeneOntologyCellularComponentbasolateral plasma membrane

ADORA1 SLC6A12 SLC6A13 SLC34A1 ATP6V0A4 LEPR SLC2A2

2.43e-04320817GO:0016323
GeneOntologyCellularComponentcell projection membrane

ADORA1 ACE2 SLC9A3 SLC34A1 ATP6V0A4 SLC2A2 SLC6A14 OPRM1

2.64e-04431818GO:0031253
GeneOntologyCellularComponentdistal axon

ADORA1 FMR1 PTPRO ITSN1 GRIA4 GRIK4 GRIK5 TENM2

2.81e-04435818GO:0150034
GeneOntologyCellularComponentneuron projection terminus

ADORA1 FMR1 ITSN1 GRIA4 GRIK4 GRIK5

2.91e-04233816GO:0044306
GeneOntologyCellularComponentdendrite

ADORA1 ADORA3 FMR1 HTR4 PTPRO ITSN1 GRIA4 GRIK4 GRIK5 TENM2 OPRM1

4.59e-048588111GO:0030425
GeneOntologyCellularComponentdendritic tree

ADORA1 ADORA3 FMR1 HTR4 PTPRO ITSN1 GRIA4 GRIK4 GRIK5 TENM2 OPRM1

4.68e-048608111GO:0097447
GeneOntologyCellularComponentspine apparatus

FMR1 OPRM1

5.25e-049812GO:0097444
GeneOntologyCellularComponentpostsynapse

ADORA1 FMR1 HTR4 PTPRO ITSN1 ELAVL1 GRIA4 NBEA GRIK4 GRIK5 TENM2 OPRM1

5.29e-0410188112GO:0098794
GeneOntologyCellularComponentionotropic glutamate receptor complex

GRIA4 GRIK4 GRIK5

7.07e-0445813GO:0008328
GeneOntologyCellularComponentneurotransmitter receptor complex

GRIA4 GRIK4 GRIK5

9.63e-0450813GO:0098878
GeneOntologyCellularComponentazurophil granule membrane

ATP8A1 ABCA13 ACP3

1.56e-0359813GO:0035577
GeneOntologyCellularComponentreceptor complex

TRBV6-7 TM7SF2 GRIA4 GRIK4 GRIK5 FCRL5 LRP1B LEPR

1.84e-03581818GO:0043235
GeneOntologyCellularComponenthippocampal mossy fiber to CA3 synapse

FMR1 GRIK4 GRIK5

2.25e-0367813GO:0098686
GeneOntologyCellularComponentasymmetric synapse

ADORA1 FMR1 PTPRO ELAVL2 GRIA4 GRIK4 GRIK5

2.51e-03477817GO:0032279
GeneOntologyCellularComponentsomatodendritic compartment

ADORA1 TRPM4 ADORA3 FMR1 HTR4 PTPRO ITSN1 GRIA4 GRIK4 GRIK5 TENM2 OPRM1

2.64e-0312288112GO:0036477
GeneOntologyCellularComponentpreribosome, large subunit precursor

MDN1 NOC2L

2.97e-0321812GO:0030687
GeneOntologyCellularComponentpostsynaptic density membrane

PTPRO GRIA4 GRIK4 GRIK5

3.25e-03157814GO:0098839
GeneOntologyCellularComponentneuron to neuron synapse

ADORA1 FMR1 PTPRO ELAVL2 GRIA4 GRIK4 GRIK5

4.16e-03523817GO:0098984
GeneOntologyCellularComponentendosome

SLC9A3 MS4A2 HTR4 SLC34A1 ITSN1 ACP3 ATP6V0A4 MFSD8 F2RL1 SLC2A2 OPRM1

5.24e-0311678111GO:0005768
GeneOntologyCellularComponenttransporter complex

TRPM4 ATP8A1 ATP6V0A4 GRIA4 MFSD8 GRIK4 GRIK5

5.46e-03550817GO:1990351
GeneOntologyCellularComponentaxon

ADORA1 FMR1 PTPRO ITSN1 GRIA4 GRIK4 GRIK5 TENM2 OPRM1

7.48e-03891819GO:0030424
GeneOntologyCellularComponentpotassium channel complex

GRIA4 GRIK4 GRIK5

7.71e-03104813GO:0034705
GeneOntologyCellularComponentpostsynaptic specialization membrane

PTPRO GRIA4 GRIK4 GRIK5

7.76e-03201814GO:0099634
MousePhenoabnormal thermal nociception

ADORA1 FMR1 ACP3 ADGRG1 GRIA4 GRIK5 F2RL1 OPRM1

9.20e-07168648MP:0002733
MousePhenoabnormal touch/ nociception

ADORA1 ADORA3 FMR1 MAP4K5 ACP3 ADGRG1 GRIA4 NBEA GRIK5 F2RL1 OPRM1

9.54e-073766411MP:0001968
MousePhenoabnormal pain threshold

ADORA1 FMR1 MAP4K5 ACP3 ADGRG1 GRIA4 GRIK5 F2RL1 OPRM1

3.25e-06267649MP:0001970
MousePhenodecreased thermal nociceptive threshold

ADORA1 ACP3 ADGRG1 OPRM1

1.06e-0454644MP:0003998
DomainIontro_rcpt

GRIA4 GRIK4 GRIK5

5.68e-0518793IPR001320
DomainLig_chan-Glu_bd

GRIA4 GRIK4 GRIK5

5.68e-0518793PF10613
DomainIono_rcpt_met

GRIA4 GRIK4 GRIK5

5.68e-0518793IPR001508
DomainGlu/Gly-bd

GRIA4 GRIK4 GRIK5

5.68e-0518793IPR019594
DomainNA_NEUROTRAN_SYMP_2

SLC6A12 SLC6A13 SLC6A14

5.68e-0518793PS00754
DomainLig_chan-Glu_bd

GRIA4 GRIK4 GRIK5

5.68e-0518793SM00918
DomainLig_chan

GRIA4 GRIK4 GRIK5

5.68e-0518793PF00060
DomainPBPe

GRIA4 GRIK4 GRIK5

5.68e-0518793SM00079
DomainSNF

SLC6A12 SLC6A13 SLC6A14

6.72e-0519793PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A12 SLC6A13 SLC6A14

6.72e-0519793PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A12 SLC6A13 SLC6A14

6.72e-0519793PS50267
DomainNa/ntran_symport

SLC6A12 SLC6A13 SLC6A14

6.72e-0519793IPR000175
DomainAdenosn_rcpt

ADORA1 ADORA3

1.05e-044792IPR001634
DomainELAD_HUD_SF

ELAVL2 ELAVL1

1.05e-044792IPR006548
DomainANF_lig-bd_rcpt

GRIA4 GRIK4 GRIK5

5.10e-0437793IPR001828
DomainANF_receptor

GRIA4 GRIK4 GRIK5

5.10e-0437793PF01094
DomainGPCR_Rhodpsn_7TM

ADORA1 OR8I2 ADORA3 HTR4 GPR85 C5AR2 OR51V1 F2RL1 OR51B4 OPRM1

5.10e-046707910IPR017452
Domain7tm_1

ADORA1 OR8I2 ADORA3 HTR4 GPR85 C5AR2 OR51V1 F2RL1 OR51B4 OPRM1

5.53e-046777910PF00001
DomainPeripla_BP_I

GRIA4 GRIK4 GRIK5

5.96e-0439793IPR028082
DomainG_PROTEIN_RECEP_F1_1

ADORA1 OR8I2 ADORA3 HTR4 GPR85 C5AR2 OR51V1 F2RL1 OR51B4 OPRM1

6.06e-046857910PS00237
DomainG_PROTEIN_RECEP_F1_2

ADORA1 OR8I2 ADORA3 HTR4 GPR85 C5AR2 OR51V1 F2RL1 OR51B4 OPRM1

6.48e-046917910PS50262
DomainGPCR_Rhodpsn

ADORA1 OR8I2 ADORA3 HTR4 GPR85 C5AR2 OR51V1 F2RL1 OR51B4 OPRM1

6.56e-046927910IPR000276
DomainHud_Sxl_RNA

ELAVL2 ELAVL1

7.78e-0410792IPR002343
DomainMFS

SLC37A2 MFSD8 SLC2A2 SLC2A5

1.14e-03108794PS50850
DomainATPase_dyneun-rel_AAA

MDN1 DNAH8

1.56e-0314792IPR011704
DomainAAA_5

MDN1 DNAH8

1.56e-0314792PF07728
DomainSugar/inositol_transpt

SLC2A2 SLC2A5

1.56e-0314792IPR003663
DomainSUGAR_TRANSPORT_2

SLC2A2 SLC2A5

2.31e-0317792PS00217
DomainMFS_dom

SLC37A2 MFSD8 SLC2A2 SLC2A5

2.51e-03134794IPR020846
DomainSUGAR_TRANSPORT_1

SLC2A2 SLC2A5

4.59e-0324792PS00216
DomainSugar_transporter_CS

SLC2A2 SLC2A5

8.07e-0332792IPR005829
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

ADORA1 ADORA3 HTR4 GRIA4 GRIK4 GRIK5 F2RL1 LEPR OPRM1

5.92e-06272689M13380
PathwayWP_GPCRS_NONODORANT

ADORA1 ADORA3 HTR4 C5AR2 GPR143 ADGRG1 F2RL1 OPRM1

4.02e-05266688MM15843
PathwayWP_GPCRS_OTHER

ADORA1 ADORA3 GPR143 ADGRG1 OPRM1

9.79e-0596685MM15939
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A12 SLC6A13 SLC6A14

9.84e-0519683M27362
PathwayREACTOME_NA_CL_DEPENDENT_NEUROTRANSMITTER_TRANSPORTERS

SLC6A12 SLC6A13 SLC6A14

9.84e-0519683MM15107
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC34A1 SLC2A2 SLC6A14

1.45e-04238687MM15076
PathwayWP_PROXIMAL_TUBULE_TRANSPORT

SLC9A3 SLC34A1 ATP6V0A4 SLC2A2

1.61e-0457684M39812
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC34A1 SLC2A2 SLC6A14

1.91e-04249687M5988
PathwayREACTOME_INTESTINAL_ABSORPTION

SLC2A2 SLC2A5

2.27e-045682M27833
PathwayREACTOME_DIGESTION_AND_ABSORPTION

CHIA SLC2A2 SLC2A5

2.29e-0425683MM15557
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

ADORA1 ADORA3 HTR4 GPR85 C5AR2 F2RL1 OPRM1

2.49e-04260687M39397
PathwayREACTOME_DIGESTION_AND_ABSORPTION

CHIA SLC2A2 SLC2A5

3.23e-0428683M27837
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TRPM4 SLC6A12 SLC6A13 SLC9A3 ATP8A1 SLC13A1 CLCA2 SLC34A1 ATP6V0A4 SLC2A2 SLC6A14

3.82e-046816811MM14985
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A12 SLC6A13 SLC13A1 SLC6A14

4.89e-0476684MM15072
PathwayREACTOME_TRANSPORT_OF_BILE_SALTS_AND_ORGANIC_ACIDS_METAL_IONS_AND_AMINE_COMPOUNDS

SLC6A12 SLC6A13 SLC13A1 SLC6A14

7.15e-0484684M27334
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

TRPM4 SLC6A12 SLC6A13 SLC9A3 ATP8A1 SLC13A1 CLCA2 SLC34A1 ATP6V0A4 SLC2A2 SLC6A14

7.32e-047366811M27287
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

GRIK4 GRIK5

1.01e-0310682M10272
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

ADORA1 ADORA3 HTR4 C5AR2 GPR143 F2RL1 OPRM1

1.03e-03330687M18334
PathwayWP_GPCRS_OTHER

ADORA3 C5AR2 GPR143 ADGRG1

1.05e-0393684M39629
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

ADORA1 ADORA3 HTR4 C5AR2 GPR143 F2RL1 OPRM1

1.09e-03333687MM14963
PathwayWP_NUCLEOTIDE_GPCRS

ADORA1 ADORA3

1.23e-0311682M39422
PathwayREACTOME_IONOTROPIC_ACTIVITY_OF_KAINATE_RECEPTORS

GRIK4 GRIK5

1.47e-0312682MM15142
PathwayWP_NUCLEOTIDE_GPCRS

ADORA1 ADORA3

1.47e-0312682MM15953
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A12 SLC9A3 SLC34A1 SLC6A14

1.82e-03108684M823
PathwayREACTOME_SIGNALING_BY_GPCR

ADORA1 ADORA3 HTR4 ITSN1 RGS22 C5AR2 GPR143 NBEA F2RL1 OPRM1

1.87e-037026810M746
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A12 SLC9A3 SLC34A1 SLC6A14

1.88e-03109684MM15074
PathwayREACTOME_TRANSMISSION_ACROSS_CHEMICAL_SYNAPSES

SLC6A12 SLC6A13 GRIA4 NBEA GRIK4 GRIK5

1.89e-03270686M15514
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

ADORA1 ADORA3

2.63e-0316682M6786
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

ADORA1 ADORA3

2.63e-0316682MM15050
Pubmed

The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.

ACE2 SLC6A13 SLC9A3 SLC34A1 SLC37A2 GRIK4 SLC2A2 SLC2A5 SLC6A14

1.95e-0921282919521566
Pubmed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

SLC6A12 SLC6A13 ADORA3 HTR4 GRIA4 NBEA GRIK4 GRIK5 LEPR OPRM1

2.43e-09300821019086053
Pubmed

Short-term plasticity of kainate receptor-mediated EPSCs induced by NMDA receptors at hippocampal mossy fiber synapses.

ADORA1 GRIK4 GRIK5

4.39e-07782317428973
Pubmed

Association analysis of the glutamic acid decarboxylase 2 and the glutamine synthetase genes (GAD2, GLUL) with schizophrenia.

GRIA4 GRIK4 GRIK5

7.01e-07882319125103
Pubmed

Splicing and editing of ionotropic glutamate receptors: a comprehensive analysis based on human RNA-Seq data.

GRIA4 GRIK4 GRIK5

1.05e-06982334100982
Pubmed

Expression of glutamate receptor subunit genes during development of the mouse retina.

GRIA4 GRIK4 GRIK5

1.05e-0698239051806
Pubmed

Monitoring protein-protein interactions between the mammalian integral membrane transporters and PDZ-interacting partners using a modified split-ubiquitin membrane yeast two-hybrid system.

SLC9A3 SLC13A1 SLC34A1 OGDHL

1.99e-063882418407958
Pubmed

High-affinity kainate receptor subunits are necessary for ionotropic but not metabotropic signaling.

GRIK4 GRIK5

5.49e-06282219778510
Pubmed

Angiotensin I-converting enzyme type 2 (ACE2) gene therapy improves glycemic control in diabetic mice.

ACE2 LEPR

5.49e-06282220660625
Pubmed

Altered COVID-19 receptor ACE2 expression in a higher risk group for cerebrovascular disease and ischemic stroke.

ACE2 LEPR

5.49e-06282232513532
Pubmed

Genetic ablation of the GluK4 kainate receptor subunit causes anxiolytic and antidepressant-like behavior in mice.

GRIK4 GRIK5

5.49e-06282222203159
Pubmed

Monogenic mouse models of social dysfunction: implications for autism.

FMR1 OPRM1

5.49e-06282223327738
Pubmed

ELAV protein HuA (HuR) can redistribute between nucleus and cytoplasm and is upregulated during serum stimulation and T cell activation.

ELAVL2 ELAVL1

5.49e-0628229763509
Pubmed

Studying the Roles of the Renin-Angiotensin System in Accelerating the Disease of High-Fat-Diet-Induced Diabetic Nephropathy in a db/db and ACE2 Double-Gene-Knockout Mouse Model.

ACE2 LEPR

5.49e-06282238203500
Pubmed

Prostatic acid phosphatase is required for the antinociceptive effects of thiamine and benfotiamine.

ADORA1 ACP3

5.49e-06282223119057
Pubmed

Polymorphisms in adenosine receptor genes are associated with infarct size in patients with ischemic cardiomyopathy.

ADORA1 ADORA3

5.49e-06282217728764
Pubmed

Role of Human Antigen R (HuR) in the Regulation of Pulmonary ACE2 Expression.

ACE2 ELAVL1

5.49e-06282235011584
Pubmed

Regulation of urinary ACE2 in diabetic mice.

ACE2 LEPR

5.49e-06282223761674
Pubmed

A 3' untranslated region variant in FMR1 eliminates neuronal activity-dependent translation of FMRP by disrupting binding of the RNA-binding protein HuR.

FMR1 ELAVL1

5.49e-06282226554012
Pubmed

Secretion and N-linked glycosylation are required for prostatic acid phosphatase catalytic and antinociceptive activity.

ADORA1 ACP3

5.49e-06282222389722
Pubmed

Overlap of polymicrogyria, hydrocephalus, and Joubert syndrome in a family with novel truncating mutations in ADGRG1/GPR56 and KIAA0556.

ADGRG1 KATNIP

5.49e-06282230982090
Pubmed

Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems.

SLC2A2 SLC2A5

5.49e-06282234215797
Pubmed

Subunit-specific desensitization of heteromeric kainate receptors.

GRIK4 GRIK5

5.49e-06282220026616
Pubmed

Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine.

ADORA1 ACP3

5.49e-06282218940592
Pubmed

Effect of ramipril on kidney, lung and heart ACE2 in a diabetic mice model.

ACE2 LEPR

5.49e-06282233811970
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

ADORA1 TRPM4 HTR4 SLC41A3 C5AR2 TM7SF2 ADGRG1 HERC2 F2RL1 OPRM1

5.73e-06697821028298427
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

FRY MDN1 FMR1 ITSN1 ELAVL2 ELAVL1 GRIA4 NBEA GRIK5 HERC2 TENM2

1.62e-05963821128671696
Pubmed

The repertoire of solute carriers of family 6: identification of new human and rodent genes.

SLC6A12 SLC6A13 SLC6A14

1.63e-052182316125675
Pubmed

Basal adenosine modulates the functional properties of AMPA receptors in mouse hippocampal neurons through the activation of A1R A2AR and A3R.

ADORA1 ADORA3

1.64e-05382226528137
Pubmed

Prostatic acid phosphatase reduces thermal sensitivity and chronic pain sensitization by depleting phosphatidylinositol 4,5-bisphosphate.

ADORA1 ACP3

1.64e-05382220685973
Pubmed

Upregulation of Angiotensin (1-7)-Mediated Signaling Preserves Endothelial Function Through Reducing Oxidative Stress in Diabetes.

ACE2 LEPR

1.64e-05382225867182
Pubmed

ACE2 pathway regulates thermogenesis and energy metabolism.

ACE2 LEPR

1.64e-05382235014608
Pubmed

Downregulation of spinal angiotensin converting enzyme 2 is involved in neuropathic pain associated with type 2 diabetes mellitus in mice.

ACE2 LEPR

1.64e-05382231987854
Pubmed

Positive regulatory control loop between gut leptin and intestinal GLUT2/GLUT5 transporters links to hepatic metabolic functions in rodents.

SLC2A2 SLC2A5

1.64e-05382219956534
Pubmed

Hypothermia in mouse is caused by adenosine A1 and A3 receptor agonists and AMP via three distinct mechanisms.

ADORA1 ADORA3

1.64e-05382227914963
Pubmed

Impact of genetic polymorphisms of SLC2A2, SLC2A5, and KHK on metabolic phenotypes in hypertensive individuals.

SLC2A2 SLC2A5

1.64e-05382223341889
Pubmed

Differential patterns of inhibition of the sugar transporters GLUT2, GLUT5 and GLUT7 by flavonoids.

SLC2A2 SLC2A5

1.64e-05382229548810
Pubmed

Molecular cloning of a novel member of the GLUT family of transporters, SLC2a10 (GLUT10), localized on chromosome 20q13.1: a candidate gene for NIDDM susceptibility.

SLC2A2 SLC2A5

1.64e-05382211247674
Pubmed

Astrocytic γ-aminobutyric acid (GABA) transporters mediate guanidinoacetate transport in rat brain.

SLC6A12 SLC6A13

1.64e-05382229175673
Pubmed

HuB and HuD repress telomerase activity by dissociating HuR from TERC.

ELAVL2 ELAVL1

1.64e-05382233589924
Pubmed

Expression of adenosine receptors in human retinal pigment epithelium cells in vitro.

ADORA1 ADORA3

1.64e-05382221542986
Pubmed

Angiotensin-converting enzyme 2 amplification limited to the circulation does not protect mice from development of diabetic nephropathy.

ACE2 LEPR

1.64e-05382227927599
Pubmed

Homeostatic action of adenosine A3 and A1 receptor agonists on proliferation of hematopoietic precursor cells.

ADORA1 ADORA3

1.64e-05382218445770
Pubmed

Hexose transporter expression and function in mouse small intestine: role of diurnal rhythm.

SLC2A2 SLC2A5

1.64e-05382219082670
Pubmed

RNA-binding proteins tristetraprolin and human antigen R are novel modulators of podocyte injury in diabetic kidney disease.

ELAVL1 LEPR

1.64e-05382232487989
Pubmed

Diabetes regulates fructose absorption through thioredoxin-interacting protein.

SLC2A2 SLC2A5

1.64e-05382227725089
Pubmed

PAP and NT5E inhibit nociceptive neurotransmission by rapidly hydrolyzing nucleotides to adenosine.

ADORA1 ACP3

1.64e-05382222011440
Pubmed

Genetic Similarities between Compulsive Overeating and Addiction Phenotypes: A Case for "Food Addiction"?

LEPR OPRM1

1.64e-05382226478196
Pubmed

Association study of polymorphisms in the GluR7, KA1 and KA2 kainate receptor genes (GRIK3, GRIK4, GRIK5) with schizophrenia.

GRIK4 GRIK5

1.64e-05382216325263
Pubmed

Sam68 promotes hepatic gluconeogenesis via CRTC2.

LEPR CRTC2

1.64e-05382234099657
Pubmed

Association of dopamine D2 receptor and leptin receptor genes with clinically severe obesity.

LEPR OPRM1

1.64e-05382223670889
Pubmed

Expression and function of hexose transporters GLUT1, GLUT2, and GLUT5 in breast cancer-effects of hypoxia.

SLC2A2 SLC2A5

1.64e-05382229913554
Pubmed

Multiple apical plasma membrane constituents are associated with susceptibility to meconium ileus in individuals with cystic fibrosis.

SLC9A3 SLC6A14

1.64e-05382222466613
Pubmed

ACE and ACE2 activity in diabetic mice.

ACE2 LEPR

1.64e-05382216804085
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

SLC6A12 SLC6A13 SLC9A3 ADGRG1 SLC2A2

2.32e-0514382520424473
Pubmed

Glutamate can act as a signaling molecule in mouse preimplantation embryos†.

GRIA4 GRIK4 GRIK5

2.47e-052482335746896
Pubmed

Distribution of kainate receptor subunits at hippocampal mossy fiber synapses.

GRIK4 GRIK5

3.28e-05482212954862
Pubmed

Systematic deletion of adenosine receptors reveals novel roles in inflammation and pyroptosis in THP-1 macrophages.

ADORA1 ADORA3

3.28e-05482233524770
Pubmed

FoxO6-mediated IL-1β induces hepatic insulin resistance and age-related inflammation via the TF/PAR2 pathway in aging and diabetic mice.

F2RL1 LEPR

3.28e-05482230974318
Pubmed

Adenosine A3 receptor deficiency exerts unanticipated protective effects on the pressure-overloaded left ventricle.

ADORA1 ADORA3

3.28e-05482218838560
Pubmed

Differential renal effects of candesartan at high and ultra-high doses in diabetic mice-potential role of the ACE2/AT2R/Mas axis.

ACE2 LEPR

3.28e-05482227612496
Pubmed

HuD RNA recognition motifs play distinct roles in the formation of a stable complex with AU-rich RNA.

ELAVL2 ELAVL1

3.28e-05482210848602
Pubmed

Hepatokine ERAP1 Disturbs Skeletal Muscle Insulin Sensitivity Via Inhibiting USP33-Mediated ADRB2 Deubiquitination.

ERAP1 LEPR

3.28e-05482235192681
Pubmed

Fractalkine/CX3CL1 engages different neuroprotective responses upon selective glutamate receptor overactivation.

ADORA1 ADORA3

3.28e-05482225653593
Pubmed

Dietary fructose-mediated adipocyte metabolism drives antitumor CD8+ T cell responses.

LEPR SLC2A5

3.28e-05482237863051
Pubmed

A3 adenosine receptor activation decreases mortality and renal and hepatic injury in murine septic peritonitis.

ADORA1 ADORA3

3.28e-05482216728466
Pubmed

A direct interaction between EXT proteins and glycosyltransferases is defective in hereditary multiple exostoses.

EXT2 GALNT5

3.28e-05482210545594
Pubmed

A1 adenosine receptor negatively modulates coronary reactive hyperemia via counteracting A2A-mediated H2O2 production and KATP opening in isolated mouse hearts.

ADORA1 ADORA3

3.28e-05482224043252
Pubmed

High Basolateral Glucose Increases Sodium-Glucose Cotransporter 2 and Reduces Sirtuin-1 in Renal Tubules through Glucose Transporter-2 Detection.

LEPR SLC2A2

3.28e-05482229717156
Pubmed

Reassessment of GLUT7 and GLUT9 as Putative Fructose and Glucose Transporters.

SLC2A2 SLC2A5

3.28e-05482228083649
Pubmed

Links between insulin resistance, adenosine A2B receptors, and inflammatory markers in mice and humans.

ADORA1 LEPR

3.28e-05482221270276
Pubmed

The CREB coactivator TORC2 is a key regulator of fasting glucose metabolism.

LEPR CRTC2

3.28e-05482216148943
Pubmed

Adenosine receptors interacting proteins (ARIPs): Behind the biology of adenosine signaling.

ADORA1 ADORA3

3.28e-05482219883624
Pubmed

Dynamics of ADAM17-Mediated Shedding of ACE2 Applied to Pancreatic Islets of Male db/db Mice.

ACE2 LEPR

3.28e-05482226441236
Pubmed

Tissue-nonspecific alkaline phosphatase acts redundantly with PAP and NT5E to generate adenosine in the dorsal spinal cord.

ADORA1 ACP3

3.28e-05482223825434
Pubmed

Insulin modulates gluconeogenesis by inhibition of the coactivator TORC2.

LEPR CRTC2

3.28e-05482217805301
Pubmed

Hu proteins regulate alternative splicing by inducing localized histone hyperacetylation in an RNA-dependent manner.

ELAVL2 ELAVL1

3.28e-05482221808035
Pubmed

A(1) and A(3) adenosine receptors inhibit LPS-induced hypoxia-inducible factor-1 accumulation in murine astrocytes.

ADORA1 ADORA3

3.28e-05482223969284
Pubmed

Molecular characterization of four pharmacologically distinct gamma-aminobutyric acid transporters in mouse brain [corrected].

SLC6A12 SLC6A13

3.28e-0548228420981
Pubmed

Tlx1/3 and Ptf1a control the expression of distinct sets of transmitter and peptide receptor genes in the developing dorsal spinal cord.

GRIA4 GRIK4 GRIK5 OPRM1

4.16e-058182422723691
Pubmed

Developmental expression patterns of kainate receptors in the mouse spinal cord.

GRIK4 GRIK5

5.47e-05582223076118
Pubmed

Embryonic and postnatal expression of four gamma-aminobutyric acid transporter mRNAs in the mouse brain and leptomeninges.

SLC6A12 SLC6A13

5.47e-0558228956109
Pubmed

A2B adenosine receptor dampens hypoxia-induced vascular leak.

ADORA1 ADORA3

5.47e-05582218056839
Pubmed

Adenosinergic regulation of the expansion and immunosuppressive activity of CD11b+Gr1+ cells.

ADORA1 ADORA3

5.47e-05582222039302
Pubmed

Overnutrition stimulates intestinal epithelium proliferation through β-catenin signaling in obese mice.

LEPR SLC2A2

5.47e-05582223884889
Pubmed

Adenosine A(1), A(2a), A(2b), and A(3) receptors in hematopoiesis. 1. Expression of receptor mRNA in four mouse hematopoietic precursor cells.

ADORA1 ADORA3

5.47e-05582219249907
Pubmed

Adenosine A(1), A(2a), A(2b), and A(3) receptors in hematopoiesis. 2. Expression of receptor mRNA in resting and lipopolysaccharide-activated mouse RAW 264.7 macrophages.

ADORA1 ADORA3

5.47e-05582219249906
Pubmed

Adenosine activation of A(2B) receptor(s) is essential for stimulated epithelial ciliary motility and clearance.

ADORA1 ADORA3

5.47e-05582221622845
Pubmed

Gs protein-coupled adenosine receptor signaling and lytic function of activated NK cells.

ADORA1 ADORA3

5.47e-05582216177079
Pubmed

Determination of kainate receptor subunit ratios in mouse brain using novel chimeric protein standards.

GRIK4 GRIK5

5.47e-05582226448475
Pubmed

Kainate receptors: pharmacology, function and therapeutic potential.

GRIK4 GRIK5

5.47e-05582218793656
Pubmed

Specific Activation of A3, A2A and A1 Adenosine Receptors in CD73-Knockout Mice Affects B16F10 Melanoma Growth, Neovascularization, Angiogenesis and Macrophage Infiltration.

ADORA1 ADORA3

5.47e-05582226964090
Pubmed

Kainate receptor subunits underlying presynaptic regulation of transmitter release in the dorsal horn.

GRIK4 GRIK5

5.47e-05582212223554
Pubmed

Selective deletion of the A1 adenosine receptor abolishes heart-rate slowing effects of intravascular adenosine in vivo.

ADORA1 ADORA3

5.47e-05582219707555
Pubmed

Molecular determinants of kainate receptor trafficking.

GRIK4 GRIK5

5.47e-05582218358623
Pubmed

Effects of targeted deletion of A1 adenosine receptors on postischemic cardiac function and expression of adenosine receptor subtypes.

ADORA1 ADORA3

5.47e-05582216679400
Pubmed

Detrimental effects of adenosine signaling in sickle cell disease.

ADORA1 ADORA3

5.47e-05582221170046
Pubmed

Adenosine, an endogenous distress signal, modulates tissue damage and repair.

ADORA1 ADORA3

5.47e-05582217396131
Pubmed

The reno-vascular A2B adenosine receptor protects the kidney from ischemia.

ADORA1 ADORA3

5.47e-05582218578565
Pubmed

Complete Disruption of the Kainate Receptor Gene Family Results in Corticostriatal Dysfunction in Mice.

GRIK4 GRIK5

5.47e-05582228228252
Cytoband7q31.32

SLC13A1 TMEM168

2.43e-04138227q31.32
GeneFamilySolute carriers

SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC41A3 SLC34A1 SLC37A2 SLC2A2 SLC2A5 SLC6A14

5.35e-073955910752
GeneFamilyAdenosine receptors

ADORA1 ADORA3

6.26e-054592211
GeneFamilyGlutamate ionotropic receptor kainate type subunits

GRIK4 GRIK5

1.04e-0455921199
CoexpressionYOSHIMURA_MAPK8_TARGETS_UP

ACE2 SLC6A12 SLC6A13 ADORA3 MS4A2 HTR4 SLC13A1 SLC34A1 RGS22 ACP3 CST8 C5AR2 GRIK4 GALNT5 F2RL1 OPRM1

1.61e-0612818116M1884
CoexpressionGSE24142_EARLY_THYMIC_PROGENITOR_VS_DN3_THYMOCYTE_FETAL_DN

ATP8A1 PTPRO ENTPD5 TM7SF2 SLC37A2 EDEM1 DNAH8

2.83e-06199817M4571
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

FRY PIEZO2 MDN1 ATP8A1 PTPRO GPR85 ELAVL2 OGDHL GRIA4 IRF2BPL NBEA LRP1B TENM2 OPRM1

6.79e-0611068114M39071
CoexpressionGSE22886_IL2_VS_IL15_STIM_NKCELL_UP

CHIA SLC13A1 ATP6V0A4 C5AR2 KATNIP SLC2A2

3.30e-05196816M4514
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#2_top-relative-expression-ranked_1000

SLC9A3 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5 ADGRG1 F2RL1 SLC2A2 SLC2A5

3.85e-073337810gudmap_kidney_adult_JuxtaGlom_Ren1_k2_1000
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_k-means-cluster#2_top-relative-expression-ranked_1000

SLC9A3 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5 F2RL1 SLC2A2 SLC2A5

8.47e-07279789gudmap_kidney_adult_RenalCortexMixed_Std_k2_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_k-means-cluster#2_top-relative-expression-ranked_1000

SLC6A13 SLC9A3 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5 F2RL1 SLC2A2 SLC2A5

4.81e-064417810gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_k2_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_1000

ACE2 SLC6A13 UPB1 SLC9A3 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5 ADGRG1 F2RL1 SLC2A2 SLC2A5

6.33e-067997813gudmap_kidney_adult_JuxtaGlom_Ren1_1000
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_1000

ACE2 SLC6A13 UPB1 SLC9A3 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5 SLFN5 F2RL1 SLC2A2 SLC2A5

1.41e-058617813gudmap_kidney_adult_RenalCortexMixed_Std_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_top-relative-expression-ranked_500

UPB1 SLC9A3 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5 ADGRG1 SLC2A2

1.58e-05400789gudmap_kidney_adult_JuxtaGlom_Ren1_500
CoexpressionAtlaskidney

ACE2 SLC6A12 SLC6A13 UPB1 SLC13A1 SLC34A1 ATP6V0A4 OGDHL

2.44e-05323788kidney
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_top-relative-expression-ranked_1000

SLC6A13 FRY SLC9A3 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5 ADGRG1 F2RL1 SLC2A2 SLC2A5

2.54e-057787812gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#2_top-relative-expression-ranked_100

ACE2 CLCA2 ARHGAP20

3.12e-0517783gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k2_100
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#3_top-relative-expression-ranked_1000

ACE2 SLC6A13 SLC13A1 SLC34A1 ENTPD5 SLC2A2

4.67e-05176786gudmap_developingKidney_e15.5_S-shaped body_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_500

PRMT6 ADORA1 ACE2 MS4A2 PTPRO SLC34A1 IGSF1 SLC2A2

1.22e-04406788gudmap_developingKidney_e15.5_S-shaped body_500
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_500

ACE2 SLC6A13 PIEZO2 PTPRO SLC34A1 ATP6V0A4 GRIA4 F2RL1

1.34e-04412788gudmap_kidney_e15.5_Podocyte_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_100

ACE2 CLCA2 CST8 ARHGAP20

1.51e-0473784gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_100
CoexpressionAtlasB cells, B.Pl.AA4-.BM, CD138+ AA4.1- CD43+, Bone marrow, avg-2

MS4A2 PGLYRP1 ABCA13 ADGRG1

1.59e-0474784GSM777030_100
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_top-relative-expression-ranked_500

ACE2 SLC6A13 UPB1 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5

1.64e-04424788gudmap_kidney_adult_RenalCortexMixed_Std_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_100

ACE2 CLCA2 CST8 ARHGAP20

1.77e-0476784gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_100
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#1_top-relative-expression-ranked_200

SLC13A1 SLC34A1 ABCA13 ATP6V0A4

1.77e-0476784gudmap_kidney_adult_JuxtaGlom_Ren1_k1_200
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_top-relative-expression-ranked_100

SLC6A13 SLC13A1 SLC34A1 SLC2A2

1.77e-0476784gudmap_developingKidney_e15.5_early proxim tubul_100
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_top-relative-expression-ranked_1000

PRMT6 ADORA1 ACE2 SLC6A13 MS4A2 SLC13A1 PTPRO SLC34A1 ENTPD5 IGSF1 SLC2A2

1.78e-048117811gudmap_developingKidney_e15.5_S-shaped body_1000
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_k-means-cluster#4_top-relative-expression-ranked_500

SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5

1.78e-04142785gudmap_kidney_adult_RenalCortexMixed_Std_k4_500
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500

ADORA1 GPM6B ATP8A1 CLCA2 ENTPD5 CST8 ADGRG1 SLC6A14

1.89e-04433788gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

GPM6B ACE2 CLCA2 CST8 ARHGAP20

2.02e-04146785gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlasalpha beta T cells, T.8Mem.LN, CD8 TCRb CD44high CD122high, Lymph Node, avg-3

MDN1 PGLYRP1 ACP3 ENTPD5 IRF2BPL F2RL1 DNAH8

2.07e-04329787GSM538395_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

ACE2 CLCA2 CST8 GRIA4 ARHGAP20

2.09e-04147785gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_500

ADORA1 GPM6B ATP8A1 CLCA2 ENTPD5 CST8 ADGRG1 SLC6A14

2.14e-04441788gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_500
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_100

ACE2 CLCA2 CST8 ARHGAP20

2.37e-0482784gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_100
CoexpressionAtlaskidney_adult_RenalCortexMixed_Std_k-means-cluster#2_top-relative-expression-ranked_200

SLC13A1 SLC34A1 ATP6V0A4

2.40e-0433783gudmap_kidney_adult_RenalCortexMixed_Std_k2_200
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_k-means-cluster#1_top-relative-expression-ranked_100

ACE2 SLC2A2

2.76e-047782gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100_k1
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_100

ACE2 PTPRO LEPR SLC2A2

2.85e-0486784gudmap_developingKidney_e15.5_Pelvic Mesenchyme_100
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_200

ACE2 CLCA2 ARHGAP20

3.39e-0437783gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_100

ACE2 CLCA2 ARHGAP20

3.39e-0437783gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k4_100
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_1000

ACE2 SLC6A13 SLC34A1 ATP6V0A4 ENTPD5 F2RL1

3.60e-04256786gudmap_kidney_P0_JuxtaGlom_Ren1_k4_1000
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_500

ACE2 SLC6A13 SLC34A1 ATP6V0A4 F2RL1

3.66e-04166785gudmap_kidney_e15.5_Podocyte_MafB_k1_500
CoexpressionAtlasdev gonad_e13.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200

ADORA1 GPM6B ENTPD5 CST8 ADGRG1

4.08e-04170785gudmap_dev gonad_e13.5_M_SertoliCell_Sox9_200
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_500

ATP8A1 PTPRO GPR85 ELAVL2

4.33e-0496784gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_500_k1
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_500

HTR4 CLCA2 TENM2

4.60e-0441783DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_500
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_top-relative-expression-ranked_200

GPM6B ENTPD5 CST8 ADGRG1 SLC6A14

4.91e-04177785gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

GPM6B ACE2 FMR1 CLCA2 ENTPD5 CST8 ADGRG1 GRIA4 ARHGAP20 SLC6A14

4.93e-047687810gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_200

CLCA2 GRIA4 ARHGAP20

4.94e-0442783gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_200
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_k-means-cluster#4_top-relative-expression-ranked_1000

ACE2 SLC6A13 SLC34A1 ATP6V0A4 ENTPD5 F2RL1

5.16e-04274786gudmap_kidney_e15.5_Podocyte_MafB_k4_1000
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#3_top-relative-expression-ranked_500

PIEZO2 GPR85 ELAVL2 GRIA4 ARHGAP20

6.46e-04188785gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500_k3
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

PIEZO2 ATP8A1 ELAVL2 GRIA4 NBEA ARHGAP20

6.70e-04288786gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_1000_k5
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#4_top-relative-expression-ranked_1000

GPM6B ENTPD5 CST8 ADGRG1 SLC6A14

6.93e-04191785gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k4_1000
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_Captopr_top-relative-expression-ranked_500

SLC9A3 SLC13A1 SLC34A1 ABCA13 ATP6V0A4 ENTPD5 ADGRG1

7.30e-04406787gudmap_kidney_adult_JuxtaGlom_Ren1_Captopr_500
CoexpressionAtlaskidney_e15.5_Podocyte_MafB_top-relative-expression-ranked_1000

ACE2 SLC6A13 PIEZO2 PTPRO SLC34A1 HIKESHI ATP6V0A4 ENTPD5 GRIA4 F2RL1

7.72e-048147810gudmap_kidney_e15.5_Podocyte_MafB_1000
CoexpressionAtlasDevelopingKidney_e15.5_Pelvic Mesenchyme_emap-8241_top-relative-expression-ranked_500

ACE2 PTPRO GPR85 GRIA4 ARHGAP20 LEPR SLC2A2

7.95e-04412787gudmap_developingKidney_e15.5_Pelvic Mesenchyme_500
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_top-relative-expression-ranked_500

ACE2 PIEZO2 ATP8A1 GPR85 GRIA4 GALNT5 LEPR

9.02e-04421787gudmap_developingKidney_e15.5_Peripheral blastema_500
CoexpressionAtlasDevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#4_top-relative-expression-ranked_100

MS4A2 PTPRO ACP3

9.26e-0452783gudmap_developingKidney_e15.5_stage III -IV renal corpusc_100_k4
CoexpressionAtlasDevelopingKidney_e15.5_Podocyte cells_emap-27915_top-relative-expression-ranked_1000

ADORA1 ACE2 ATP8A1 MS4A2 PTPRO GRIA4 ARHGAP20 TENM2 LEPR SLC2A2

9.47e-048367810gudmap_developingKidney_e15.5_Podocyte cells_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_500

ATP8A1 HTR4 CLCA2 PTPRO GPR85 ELAVL2 TENM2

9.80e-04427787DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_500
CoexpressionAtlasDevelopingKidney_e13.5_podocyte cells_emap-27773_top-relative-expression-ranked_500

ACE2 PIEZO2 PTPRO GRIA4 ARHGAP20 TENM2 LEPR

1.03e-03431787gudmap_developingKidney_e13.5_podocyte cells_500
ToppCellCOVID-19-kidney-PCT-S1/S2|kidney / Disease (COVID-19 only), tissue and cell type

ACE2 SLC6A13 UPB1 SLC13A1 SLC34A1 ENTPD5 SLC2A2

5.01e-08184827dc71f22583fc54b89b242cbb602f4bbe86f576ec
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A12 SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

1.13e-06183826facd6dbe0851b537d70a899ac7485714ab27d071
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Degenerative_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 UPB1 SLC13A1 SLC34A1 ADGRG1 SLC2A2

1.28e-061878263ae3b8de1a195d4d5057cf3c64fcdb5f48681ce5
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 SLC13A1 SLC34A1 ADGRG1 GRIA4 SLC2A2

1.45e-061918263c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 SLC13A1 SLC34A1 ADGRG1 GRIA4 SLC2A2

1.45e-061918261c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellE16.5-samps-Epithelial-Alveolar_epithelial_precursor-Noncycling_AT1_Precursor|E16.5-samps / Age Group, Lineage, Cell class and subclass

SLC6A12 SLC6A13 ATP8A1 GPR85 SLC6A14

9.71e-061548258a643d91896af9b630a715fb284c1523d01ad1a3
ToppCellPND07-Immune-Immune_Myeloid-Granulocytic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA3 MS4A2 PGLYRP1 SLC41A3 C5AR2

9.71e-06154825f92d83c5f8b532fe5624f1cd352632f543d96ea9
ToppCell5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADORA1 CHIA CLCA2 TM7SF2 USP35

1.20e-051618257c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPM6B PGLYRP1 SLC34A1 GRIK5 OPRM1

1.48e-0516882504a7810f95196a21325356b42084f96c11af5964
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

1.48e-05168825fa0d251693935116adf633d02b7ec4a295100865
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 TM7SF2 KATNIP GRIK5 OPRM1

1.48e-05168825de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCelldroplet-Lung-nan-21m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 MS4A2 PGLYRP1 SLC41A3 ADGRG1

1.66e-051728251b133be191252e7053faeacf9547730c3ae28d21
ToppCelldroplet-Lung-nan-21m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 MS4A2 PGLYRP1 SLC41A3 ADGRG1

1.66e-05172825b3c53fd7e50f36de6a8585ae21d04e17932f262c
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADORA1 SLC6A13 ENTPD5 LEPR SLC2A2

1.80e-051758255c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCellCOVID-19-kidney-PCT-S1/S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

1.95e-0517882523a12d3d971b857d5be8e907334d1f6b49eeeb32
ToppCelldroplet-Marrow-nan-24m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 ADORA3 MS4A2 SLC41A3 ADGRG1

1.95e-05178825cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

2.06e-051808251363b3254470f6ff98630d1df83a1bdbacc137e0
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 ADORA3 MS4A2 SLC41A3 ADGRG1

2.06e-0518082541e8155cc7b3dac9d496e4077845ca6af1591a5c
ToppCellCOVID-19-kidney-Stressed_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

2.12e-051818256980ea624151da32b7f537f263e40fcb87a02e81
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

2.17e-05182825e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

2.17e-0518282557bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 UPB1 SLC9A3 SLC13A1 SLC34A1

2.23e-0518382584b64cf728629c3af9a8d2ed15b93adf562c54b8
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACE2 SLC6A12 SLC6A13 UPB1 SLC13A1

2.29e-051848259434731f651820b05335085582960f08fbf895de
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 ADORA3 MS4A2 SLC41A3 ADGRG1

2.35e-051858255527fa9d2e0b2f3607602e18ba94de4e9bbc6824
ToppCellCOVID-19-kidney-Mito-rich_PCT|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

2.35e-051858251bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ACE2 SLC6A12 SLC6A13 UPB1 SLC13A1

2.41e-05186825a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellCOVID-19-kidney-Stressed_PCT|kidney / Disease (COVID-19 only), tissue and cell type

ACE2 SLC6A13 UPB1 SLC13A1 SLC2A2

2.48e-05187825acd305475f3609800af0d7bc68d83ef41228080b
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A12 SLC6A13 ACP3 GPR143

2.53e-0592824d2c1d25e5bb6ba4f406e916e3c0a5ad05492e59d
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn.Col15a1_(Col15a1)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A12 SLC6A13 ACP3 GPR143

2.53e-0592824926e02725a03d8473eda25d4aef63e34a6566224
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC9A3 ABCA13 NBEA GALNT5 SLC6A14

2.67e-0519082523f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC9A3 ABCA13 NBEA GALNT5 SLC6A14

2.67e-051908253c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHIA ATP8A1 CST8 ADGRG1 SLC6A14

2.81e-0519282513e4b17d7a592604140777aca235f795df6b3f91
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHIA ATP8A1 CST8 ADGRG1 SLC6A14

2.81e-05192825f51b3fd962263920a6cae783ca7af13f5eb7aaa3
ToppCelldroplet-Lung-3m-Epithelial-alveolar_epithelial-type_II_pneumocyte|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CHIA ATP8A1 CST8 ADGRG1 SLC6A14

2.81e-051928256244541688f85917018a057aa0b3e5972934dfbc
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACE2 SLC6A13 SLC13A1 ENTPD5 SLC2A5

2.81e-051928253e1a4cb0d83efd502c8613d41a1692bdda5860ed
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8A1 OGDHL ST8SIA5 TENM2 SLC2A2

3.02e-05195825bd8e24dd598990204998d1dd853ba7a53dc0107e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLC9A3 PIEZO2 HTR4 USP35 TENM2

3.02e-05195825f5e91ce20a7ce528dc4c1a968c7bf096bf45c528
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLCA2 MAP4K5 NBEA GALNT5 F2RL1

3.18e-05197825d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CLCA2 MAP4K5 NBEA GALNT5 F2RL1

3.18e-0519782580b05c8ad9c1edc5dea3236079372475431343fe
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 UPB1 SLC13A1 SLC34A1 SLC2A2

3.18e-051978259b038dac4d4d306aa40ec07d79374c4fe9c604a6
ToppCellEpithelial_cells-Epithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

SLC6A13 UPB1 SLC13A1 SLC34A1 OGDHL

3.25e-0519882552e9d41a1726bc1140df6baec9f17a534448ac8b
ToppCellEpithelial_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

SLC6A13 UPB1 SLC13A1 SLC34A1 OGDHL

3.25e-05198825eeec789d226171f30799577cc37c07bdced2e3cb
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 SLC13A1 SLC34A1 ENTPD5 SLC2A2

3.33e-051998254bde35e5df019189433d65d415e29a0c1145ac66
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuronal|10w / Sample Type, Dataset, Time_group, and Cell type.

ETFB ELAVL2 GRIA4 NBEA TENM2

3.41e-05200825979258173b82f37aeaaedd53b4a527da1dbe1b80
ToppCellBrain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate|2m / Sample Type, Dataset, Time_group, and Cell type.

FRY PTPRO HIKESHI GPR85 ELAVL2

3.41e-052008252a635694844ddabcd98462c5636a6f41a3f08a46
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SLC6A13 SLC13A1 SLC34A1 ENTPD5 SLC2A2

3.41e-05200825825aad08431dd6b54aa636ace6efc821dfaf8014
ToppCellTCGA-Testes-Primary_Tumor-Testicular_Germ_Cell_Tumor-Testicular_Germ_Cell_Tumor-4|TCGA-Testes / Sample_Type by Project: Shred V9

CHIA MS4A2 GALNT5 SLC6A14

5.48e-051128243ec029eac64247c5e48074dad5c71df690e84f4c
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACE2 GPR143 ELAVL2 GRIK4

6.07e-05115824ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACE2 GPR143 ELAVL2 GRIK4

6.07e-051158247a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACE2 GPR143 ELAVL2 GRIK4

6.07e-05115824c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCellEndothelial-Endothelial-F|Endothelial / shred on cell class and cell subclass (v4)

PTPRO GRIK5 SLFN5 DNAH8

7.64e-051228242cb8bb63c69aed4d4504b9d97219b8707666f950
ToppCellControl-PLT_5|World / Disease Group and Platelet Clusters

SLC34A1 GPR85 GRIA4 TENM2

8.66e-051268244ba753c4e83eb1d41964edfa22135e047f06c481
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HTR4 GPR85 GPR143 USP35

9.21e-051288242cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ACP3 SLC37A2 GALNT5 LRP1B

9.21e-05128824003e133469899a9abe3a7f6d7f580583b281f412
ToppCellFrontal_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

SLC6A12 SLC6A13 ATP6V0A4 LEPR

9.49e-05129824856255fbfc7f95642000cfd7704141b2388f7c5c
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Mast-Mast_cells-Mast-cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SLC6A12 MS4A2 SLC13A1 FCRL5

1.07e-0413382481189e8516a431d5890a0909f9fc7c82ec3442bc
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

SLC6A13 SLC34A1 GRIA4 TENM2

1.16e-0413682427a41463e6f16deb5b1d4f17fefded9959038c07
ToppCellPBMC-Control-Hematopoietic-Platelet-Platelet-plt_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

SLC6A13 SLC34A1 GRIA4 TENM2

1.16e-0413682488b5c839d0446c6d6b7e81fc4d48f5e7e96eea11
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1-Inhibitory_Gad1Gad2_Id2.Tac1_(Interneuron,_Neurogliaform1)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

BTN2A2 SLC9A3 PIEZO2

1.51e-0456823c1bdee477c871c03d60feed26b24d9f3d4171cb6
ToppCellHippocampus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Tac1-Inhibitory_Gad1Gad2_Id2.Tac1_(Interneuron,_Neurogliaform1)|Hippocampus / BrainAtlas - Mouse McCarroll V32

BTN2A2 SLC9A3 PIEZO2

1.51e-0456823c78cbec68922b382595758e100dda9d284836c25
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell|E18.5-samps / Age Group, Lineage, Cell class and subclass

ACE2 PGLYRP1 GPR85 IGSF1

1.65e-0414982482edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar|E18.5-samps / Age Group, Lineage, Cell class and subclass

ACE2 PGLYRP1 GPR85 IGSF1

1.65e-0414982414a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA3 MS4A2 SLC41A3 C5AR2

1.65e-04149824c9334f319a0c943268e54b6f0c9446736172c3a9
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Myeloid-neutrophil|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PGLYRP1 ABCA13 ACP3 OPRM1

1.70e-041508246e806a028c0519489151c181d9907e05289e27e0
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8|TCGA-Thymus / Sample_Type by Project: Shred V9

PIEZO2 RGS22 ARHGAP20 LEPR

1.74e-041518245906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCelldroplet-Lung-3m-Hematologic-myeloid-neutrophil-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A13 PGLYRP1 ACP3 C5AR2

1.83e-04153824ce6e462ce4dbaf9d265f1f9e2f791efbba8c1dd0
ToppCelldroplet-Lung-3m-Hematologic-myeloid-neutrophil|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A13 PGLYRP1 ACP3 C5AR2

1.83e-041538249dba38574908f31a1194b8a339868f5e4be1be71
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Vgll3_(Dentate_hilum?)|Hippocampus / BrainAtlas - Mouse McCarroll V32

MS4A2 SLC13A1 SLC34A1

1.85e-0460823aa75fef294803ec6396c7d2c1f51d52bc4a5b43f
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Calb2-Excitatory_Neuron.Slc17a7.Calb2-Vgll3_(Dentate_hilum?)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

MS4A2 SLC13A1 SLC34A1

1.85e-0460823069fbabfd0e48e5809ff01a026439fd0bd017779
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

UPB1 SLC13A1 SLC34A1 ATP6V0A4

1.88e-0415482489a60a79d07466d7ad05888d10a72d3b1ab384af
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 UPB1 PGLYRP1 FCRL5

1.88e-041548241e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

UPB1 SLC13A1 SLC34A1 ATP6V0A4

1.88e-04154824f1fea1a87e977221fa125b62287368be9af4987d
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

UPB1 SLC13A1 SLC34A1 ATP6V0A4

1.88e-04154824b5604c0b0b9b283352a3f612f40883b9123475d1
ToppCellTCGA-Bone_and_Soft_Tissue-Solid_Tissue_Normal-Connective_tissue_normal-Connective_tissue_normal-1|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

UPB1 SLC13A1 SLC34A1 ATP6V0A4

1.88e-04154824160b170a3ade8b246843c9854af332475c047ba0
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 FRY PTPRO TENM2

1.92e-04155824e7f49e2fdaf184fa6b4e685518004e7deff1316d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADORA1 FRY PTPRO TENM2

1.92e-041558245a872ca70ae8c30b57f45a6772d7bf565e0c2663
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 SLC6A13 TM7SF2 SLC2A2

1.97e-04156824e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCelldroplet-Lung-nan-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A13 PGLYRP1 ACP3 C5AR2

2.02e-041578243cffedafff31efb5b3259194157b54a768367459
ToppCelldroplet-Lung-nan-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A13 PGLYRP1 ACP3 C5AR2

2.02e-04157824f87e867a394b0453ebd92c592e80450caf5902cb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SLC9A3 ACP3 C5AR2 OGDHL

2.12e-04159824c186bf05c61fac348cf41973827cced83fafd58a
ToppCelldroplet-Fat-SCAT-30m-Hematologic-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 ADORA3 IGSF1 TENM2

2.17e-0416082467ee7a314d7d4d3ea206e0158083f36f6dd7e80b
ToppCelldroplet-Fat-SCAT-30m-Hematologic|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 ADORA3 IGSF1 TENM2

2.17e-04160824759749f708c3a2b36692d42499f19aff937e592f
ToppCelldroplet-Fat-SCAT-30m-Hematologic-erythroblast|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 ADORA3 IGSF1 TENM2

2.17e-04160824fc76337ad766c859db390ef8b6fb9caeaace3a56
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA1 ACE2 CHIA ATP8A1

2.22e-04161824c4970501c038ed36de447da70eabff020ad78713
ToppCellPND03-Epithelial-Epithelial_Airway-Neurosecretory-Secretory|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ADORA1 ACE2 CHIA ATP8A1

2.22e-0416182441a89a3d99a9bd6039a3d881d1d9dcd18bc07f25
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-brush_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACE2 SLC6A13 ENTPD5 SLC2A5

2.28e-041628246972d45f4bd4b6522bf93295f7e9dca7c6cba1f3
ToppCellfacs-Lung-ENDOMUCIN-18m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRO NOC2L SLC37A2 USP35

2.39e-0416482454f8f11d2fa899005530c08e7a1ee728c7b0799c
ToppCelldroplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A12 ADORA3 UPB1 SLC34A1

2.39e-04164824cfe07a1ebed8aecb08d0476db71fe314998d54aa
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

HTR4 ATP6V0A4 OGDHL OPRM1

2.39e-04164824d847d509bb1791638032ade6755d8164586b5bd5
ToppCelldroplet-Lung-3m-Hematologic-myeloid-plasmacytoid_dendritic_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SLC6A12 ADORA3 UPB1 SLC34A1

2.39e-041648246d331e74efecb4733d87653f86cd67247be05025
ToppCellPND10-Epithelial-Epithelial_Airway-Neurosecretory-Secretory-Secretory_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ACE2 CHIA GALNT5 SLC6A14

2.39e-041648246ea188e17895961cd112152fb111d08641cc5e45
ToppCellfacs-Lung-Endomucin-3m-Myeloid-neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 PGLYRP1 ACP3 C5AR2

2.50e-041668245126d8f02314717eed341d867856fd4fe16c5118
ToppCelldroplet-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2-17-52|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRO NOC2L SLC37A2 SLFN5

2.50e-04166824de319c960b0cd90b294f677d1ea1b013a2ce2d53
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 ADORA3 MS4A2 SLC41A3

2.50e-04166824c22b0f3bf990d94b615a3aacee5de548da2db628
ToppCellfacs-Marrow-T_cells-18m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM4 ADORA3 MS4A2 SLC41A3

2.50e-041668240975fc165bcc7e85f053d9d0244fffe407c23571
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Neutrophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC6A12 PGLYRP1 ACP3 C5AR2

2.50e-041668243037bdca38c3a65eacfa644219cc43c54e303749
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADORA3 UPB1 GPR85 SLC37A2

2.50e-041668241ca888ae8168707493f19ee52a89d7c70e6cb51d
ToppCelldroplet-Lung-1m-Hematologic-myeloid-plasmacytoid_dendritic_cell-plasmacytoid_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADORA3 UPB1 GPR85 SLC37A2

2.50e-041668244cba4ca1aa2321b9ef7cd230932b890d2434a252
ToppCellfacs-Trachea-nan-18m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIEZO2 ATP6V0A4 CST8 C5AR2

2.56e-041678247b1fd19946cee67dae68f0f0d98420abcd532482
ToppCellfacs-Trachea-18m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PIEZO2 ATP6V0A4 CST8 C5AR2

2.56e-04167824102b3d160a44c8623fab1fd10e9054178c42a78b
DrugAC1L1B1W

ADORA1 SLC6A13 MAP4K5 GRIA4 GRIK4 GRIK5

5.08e-0784806CID000001248
Druggamma-aminobutyric acid

ADORA1 SLC6A12 SLC6A13 ADORA3 UPB1 HTR4 CLCA2 GRIA4 GRIK4 GRIK5 OPRM1

8.15e-074748011CID000000119
DrugLy294486

GRIA4 GRIK4 GRIK5

3.46e-069803CID005311255
DrugLY339434

GRIA4 GRIK4 GRIK5

3.46e-069803CID006324635
DrugAC1Q3ZOL

ADORA1 SLC6A13 ADORA3 CLCA2 GRIA4 GRIK4 GRIK5 OPRM1

3.50e-06258808CID000002376
Drugibotenic acid

CLCA2 MAP4K5 GRIA4 GRIK4 GRIK5 OPRM1

4.55e-06122806CID000001233
Drugwillardine

GRIA4 GRIK4 GRIK5 OPRM1

4.71e-0632804CID000005123
Drugalpha-methyl-4-carboxyphenylglycine

FMR1 GRIA4 GRIK4 GRIK5

4.71e-0632804CID000001222
Druganiracetam

CST8 GPR143 GRIA4 GRIK4 GRIK5 HERC2

6.56e-06130806CID000002196
Drugsym 2206

GRIA4 GRIK4 GRIK5

6.75e-0611803CID005039877
DrugAtpa

GRIA4 GRIK4 GRIK5

8.98e-0612803CID000002252
DrugVUF 5455

ADORA1 ADORA3

1.22e-052802ctd:C438612
DrugPD 81723

ADORA1 ADORA3

1.22e-052802ctd:C075004
Drugtetradotoxin

ADORA1 SLC6A13 ADORA3 HTR4 GRIA4 GRIK4 GRIK5 F2RL1 OPRM1

1.92e-05428809CID000020382
Drugdecahydroisoquinoline

GRIA4 GRIK4 GRIK5

2.26e-0516803CID000097812
Drugsodium

TRPM4 SLC6A12 SLC6A13 SLC9A3 SLC13A1 SLC34A1 ATP6V0A4 GRIA4 GRIK4 GRIK5 SLC2A2 SLC2A5 SLC6A14

2.36e-059448013CID000000923
Drugmethylenecyclopropylglycine

ADORA1 FMR1 GRIA4 GRIK4

2.65e-0549804CID000441452
DrugL-CCG-I

ADORA1 GRIA4 GRIK4 GRIK5

2.88e-0550804CID000001271
DrugQuinoxaline

ADORA3 GRIA4 GRIK4 GRIK5

3.37e-0552804CID000007045
Drug9-chloro-2-(2-furyl)-5-phenylacetylamino(1,2,4)triazolo(1,5-c)quinazoline

ADORA1 ADORA3

3.65e-053802ctd:C110041
DrugAminophylline

ADORA1 ADORA3

3.65e-053802DB01223
Drug9-methyladenine

ADORA1 ADORA3 GRIK4

3.89e-0519803CID000069689
DrugLY382884

GRIA4 GRIK4 GRIK5

3.89e-0519803CID000656723
Drug13-methoxyibogamine

GRIA4 GRIK4 GRIK5 OPRM1

3.91e-0554804CID000065749
Drug5-CT

ADORA1 ADORA3 HTR4 ELAVL1

4.21e-0555804CID000001809
DrugIDRA 21

GRIA4 GRIK4 GRIK5

4.56e-0520803CID000003688
DrugAC1N8N2J

GRIA4 GRIK4 GRIK5

4.56e-0520803CID004346372
Drugchlorcyclizine

ACP3 GRIK4 GRIK5

5.31e-0521803CID000002710
DrugCX546

GRIA4 GRIK4 GRIK5

5.31e-0521803CID000002890
DrugAC1L1B62

GRIA4 GRIK4 GRIK5

5.31e-0521803CID000001299
Drugmethylisobutylamiloride

ADORA1 SLC9A3 SLC34A1

5.31e-0521803CID000073314
DrugSR 95531

SLC6A13 GRIA4 GRIK4 GRIK5

5.55e-0559804CID000005275
DrugMPEP

FMR1 GRIA4 GRIK4 GRIK5

5.55e-0559804CID003025961
Drugglibenclamide

ADORA1 TRPM4 ADORA3 CLCA2 ABCA13 F2RL1 SLC2A2 CRTC2

5.90e-05382808CID000003488
DrugProcaine hydrochloride [51-05-8]; Down 200; 14.6uM; MCF7; HT_HG-U133A

GPM6B BTN2A2 MAP4K5 GPR143 GRIK5 LEPR

6.13e-051938065430_DN
DrugNS 102

GRIA4 GRIK4 GRIK5

6.13e-0522803CID005282252
DrugCX516

GRIA4 GRIK4 GRIK5

6.13e-0522803CID000148184
DrugDubinidine [22964-77-8]; Up 200; 14.6uM; PC3; HT_HG-U133A

PIEZO2 PGLYRP1 ACP3 CST8 GPR143 GRIK5

6.31e-051948065774_UP
DrugAmprolium hydrochloride [137-88-2]; Up 200; 12.6uM; MCF7; HT_HG-U133A

HTR4 PGLYRP1 ERAP1 ACP3 GRIK5 SLC2A5

6.67e-051968061479_UP
DrugPilocarpine nitrate [148-72-1]; Up 200; 14.8uM; HL60; HT_HG-U133A

ADORA1 GPM6B ENTPD5 ST8SIA5 F2RL1 SLC2A5

6.86e-051978062438_UP
DrugMemantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A

CLCA2 ACP3 GPR85 ELAVL2 SLC2A5 OPRM1

6.86e-051978064135_UP
DrugYM90K

GRIA4 GRIK4 GRIK5

7.03e-0523803CID005486547
DrugWY-14643; Down 200; 100uM; MCF7; HG-U133A

ACE2 HTR4 ITSN1 ACP3 LEPR OPRM1

7.06e-05198806368_DN
DrugLobelanidine hydrochloride [6112-86-3]; Up 200; 10.6uM; MCF7; HT_HG-U133A

ADORA1 GPM6B SLC6A12 HTR4 IGSF1 SLC2A5

7.06e-051988065500_UP
Drugaminothiazole 6

GRIK4 GRIK5

7.28e-054802CID005329388
Drugadenosine 5'-methylenediphosphate

ADORA1 ADORA3

7.28e-054802ctd:C008436
Drugalpha,beta-methyleneadenosine 5'-diphosphate

ADORA1 ADORA3

7.28e-054802ctd:C523965
Drug1-propylxanthine

ADORA1 ADORA3

7.28e-054802CID000128525
Drugacromelic acid B

GRIK4 GRIK5

7.28e-054802CID000158974
DrugBrn 1074551

GRIK4 GRIK5

7.28e-054802CID000120220
Drug4-methyleneglutamic acid

GRIK4 GRIK5

7.28e-054802CID000096407
DrugdiCl-HQC

GRIK4 GRIK5

7.28e-054802CID003018579
DrugAdenosine

ADORA1 ADORA3

7.28e-054802DB00640
Drug1,3-diethylxanthine

ADORA1 ADORA3

7.28e-054802CID000101420
DrugCGP 39653

GRIA4 GRIK4 GRIK5

8.02e-0524803CID006437837
Drug4,4'-diisothiocyanostilbene-2,2'-disulfonic acid

ADORA1 ADORA3 SLC9A3 SLC13A1 CLCA2 SLC34A1

8.78e-05206806CID000040600
DrugNs102

GRIA4 GRIK4 GRIK5

9.09e-0525803CID005311098
Drug1ph0

ADORA3 MS4A2 PGLYRP1

9.09e-0525803CID000447837
Druggavestinel

GRIA4 GRIK4 GRIK5

9.09e-0525803CID006450546
DrugCPD-463

ACE2 SLC13A1 CST8

9.09e-0525803CID000440634
DrugAC1L8WBM

SLC6A13 FMR1 SLC34A1 MAP4K5 GRIA4

1.15e-04135805CID000388647
Drugifenprodil

ADORA1 GRIA4 GRIK4 GRIK5

1.15e-0471804CID000003689
DrugL 659877

ADORA1 ADORA3 F2RL1

1.15e-0427803CID000164213
DrugL-689,560

GRIA4 GRIK4 GRIK5

1.15e-0427803CID000121918
Drugalverine

HTR4 TM7SF2

1.21e-045802CID000003678
Drugbromowillardiine

GRIK4 GRIK5

1.21e-045802CID000167842
Drugipenoxazone

GRIK4 GRIK5

1.21e-045802CID000065882
DrugpBB-PzDA

GRIK4 GRIK5

1.21e-045802CID000124528
Drug125I-azido-PAPA-APEC

ADORA1 ADORA3

1.21e-045802CID003083135
DrugGP683

ADORA1 ADORA3

1.21e-045802CID005311109
Drugethyl propiolate

GRIK4 GRIK5

1.21e-045802CID000012182
DrugSDZ WAG 994

ADORA1 ADORA3

1.21e-045802CID000164305
Drug3-hydroxy-2-quinoxalinecarboxylic acid

GRIK4 GRIK5

1.21e-045802CID000071001
DrugOndansetron

HTR4 OPRM1

1.21e-045802DB00904
Drugpyrimidine-2,4-dione

GRIK4 GRIK5

1.21e-045802CID000150747
Drugisoquercetrin

SLC2A2 SLC2A5

1.21e-045802CID005480505
Drugaptiganel

GRIA4 GRIK4 GRIK5

1.28e-0428803CID000060839
DrugC-PP

GRIA4 GRIK4 GRIK5

1.28e-0428803CID000001228
DrugAC1NUW3V

GRIA4 GRIK4 GRIK5

1.43e-0429803CID005462126
Drug2,4-diaminobutyric acid

SLC6A12 SLC6A13 OPRM1

1.43e-0429803CID000000470
Drugketobemidone

GRIA4 GRIK4 GRIK5

1.43e-0429803CID000010101
Drugcis-2,3-piperidine dicarboxylic acid

GRIA4 GRIK4 GRIK5

1.58e-0430803CID000001226
DrugLY293558

GRIA4 GRIK4 GRIK5

1.58e-0430803CID000127894
DrugAC1L32TU

GRIA4 GRIK4 GRIK5

1.58e-0430803CID000107831
DrugGYKI 53655

GRIA4 GRIK4 GRIK5

1.58e-0430803CID000126757
DrugAC1Q5UBL

SLC6A12 SLC6A13 GRIA4 GRIK4 GRIK5

1.65e-04146805CID000005466
DrugLY235959

GRIA4 GRIK4 GRIK5

1.75e-0431803CID000131938
DrugNPC 12626

GRIA4 GRIK4 GRIK5

1.75e-0431803CID000108099
Drug4-methylglutamic acid

GRIA4 GRIK4 GRIK5

1.75e-0431803CID000005365
Drugeliprodil

GRIA4 GRIK4 GRIK5

1.75e-0431803CID000060703
Drug3-acetylisoquinoline

GRIK4 GRIK5

1.81e-046802CID000124656
DrugBeta,gamma Methylene Atp

ADORA1 ADORA3

1.81e-046802CID005311019
Drug[18f]cpfpx

ADORA1 ADORA3

1.81e-046802CID005461879
DrugFK352

ADORA1 ADORA3

1.81e-046802CID006442241
DrugCp-66713

ADORA1 ADORA3

1.81e-046802CID000124473
DrugSHA 118

ADORA1 ADORA3

1.81e-046802CID000131433
DrugSHA 91

ADORA1 ADORA3

1.81e-046802CID000131450
DrugI-ABOPX

ADORA1 ADORA3

1.81e-046802CID000163889
DrugHNBTG

ADORA1 ADORA3

1.81e-046802CID000162449
DrugKW-6002

ADORA1 ADORA3 GRIA4

1.93e-0432803CID005311037
DiseaseFanconi syndrome (is_implicated_in)

SLC34A1 SLC2A2

7.08e-062792DOID:1062 (is_implicated_in)
DiseaseIntestinal Obstruction

SLC9A3 SLC6A14

2.12e-053792C0021843
DiseaseCYSTIC FIBROSIS MODIFIER 1

SLC9A3 SLC6A14

4.23e-054792C1859047
DiseaseDe Toni-Debre-Fanconi Syndrome

SLC34A1 SLC2A2

4.23e-054792C1857395
DiseaseFanconi-Bickel Syndrome

SLC34A1 SLC2A2

4.23e-054792C3495427
DiseaseAdult Fanconi syndrome

SLC34A1 SLC2A2

4.23e-054792C0341703
DiseaseFanconi Syndrome

SLC34A1 SLC2A2

7.04e-055792C0015624
Diseaseleptin receptor measurement

MAP4K5 LEPR

7.04e-055792EFO_0004635
Diseasecreatinine measurement, chronic kidney disease

SLC6A13 SLC34A1 MAP4K5

1.14e-0435793EFO_0003884, EFO_0004518
DiseaseSchizophrenia

ADORA1 SLC6A12 FMR1 HTR4 ABCA13 ELAVL2 GRIA4 GRIK4 GRIK5 OPRM1

1.22e-048837910C0036341
Diseasetriacylglycerol 58:6 measurement

LRP1B TENM2

1.96e-048792EFO_0010440
DiseasePruritus

F2RL1 OPRM1

1.96e-048792C0033774
Diseaseserum metabolite measurement

SLC6A12 SLC6A13 UPB1 SLC9A3 ERAP1 MAP4K5 GRIK4 GRIK5 FCRL5 ARHGAP20

2.11e-049457910EFO_0005653
DiseaseDrug habituation

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C0013170
DiseaseDrug abuse

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C0013146
DiseasePrescription Drug Abuse

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C4316881
DiseaseSubstance-Related Disorders

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C0236969
DiseaseDrug Use Disorders

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C0013222
DiseaseDrug Dependence

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C1510472
DiseaseSubstance Dependence

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C0038580
DiseaseSubstance Use Disorders

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

GRIA4 DNAH8 TENM2 OPRM1

2.63e-04115794C0029231
DiseaseSubstance abuse problem

GRIA4 DNAH8 TENM2 OPRM1

2.71e-04116794C0740858
Diseasebody mass index, fasting blood glucose measurement

MAP4K5 ETFB SLC2A2

3.51e-0451793EFO_0004340, EFO_0004465
Disease3-aminoisobutyrate measurement

SLC6A13 MAP4K5

4.59e-0412792EFO_0010980
Diseasenon-alcoholic steatohepatitis

MAP4K5 LEPR

4.59e-0412792EFO_1001249
Diseaserenal sinus adipose tissue measurement

FCRL5 ARHGAP20

5.42e-0413792EFO_0004864
Diseasesulfate measurement

SLC13A1 SLC34A1

6.31e-0414792EFO_0007864
Diseasechronic obstructive pulmonary disease (is_implicated_in)

F2RL1 LRP1B LEPR

6.53e-0463793DOID:3083 (is_implicated_in)
DiseaseYKL40 measurement

ADORA1 MAP4K5

7.27e-0415792EFO_0004869
Diseaseglaucoma

GPM6B GRIK5 HERC2 LRP1B

7.91e-04154794MONDO_0005041
Diseasecentral nervous system disease (implicated_via_orthology)

GRIA4 IRF2BPL

8.29e-0416792DOID:331 (implicated_via_orthology)
Diseaseasthma (is_implicated_in)

ADORA1 CHIA MS4A2 F2RL1

8.50e-04157794DOID:2841 (is_implicated_in)
Diseaseserum albumin measurement

FRY MAP4K5 ACP3 ETFB IRF2BPL GRIK5 LEPR

1.05e-03592797EFO_0004535
Diseaseage at menarche

HTR4 ETFB USP35 IGSF1 LRP1B TENM2 LEPR

1.07e-03594797EFO_0004703
Diseaseleptin measurement

MAP4K5 LRP1B DNAH8

1.36e-0381793EFO_0005000
Diseaseage at voice drop

IGSF1 LEPR

1.58e-0322792EFO_0007888
DiseaseBMI-adjusted fasting blood glucose measurement

MAP4K5 SLC2A2

1.73e-0323792EFO_0008036
Diseaseinsulin sensitivity measurement

SLC6A12 MAP4K5

1.73e-0323792EFO_0004471
DiseaseBipolar Disorder

SLC6A13 HTR4 ABCA13 GRIK4 GRIK5 DNAH8

1.78e-03477796C0005586
Diseasecarnosine measurement

GRIK5 TENM2

1.88e-0324792EFO_0010470
Diseasetriacylglycerol 58:7 measurement

MAP4K5 ITSN1

1.88e-0324792EFO_0010441
Diseasefasting blood glucose measurement, HOMA-B, fasting blood insulin measurement

MAP4K5 ETFB

2.04e-0325792EFO_0004465, EFO_0004466, EFO_0004469
DiseaseIschemia

ADORA1 ADORA3

2.56e-0328792C0022116
DiseaseBell's palsy

SLC41A3 GRIK5 DNAH8

2.62e-03102793EFO_0007167

Protein segments in the cluster

PeptideGeneStartEntry
PFWGAIFFSISGMLS

MS4A2

101

Q01362
FVVGLTPMFGWNNLS

ADORA1

136

P30542
LVSFLVGLTPMFGWN

ADORA3

136

P0DMS8
IGGWNFGTAPFTAMV

CHIA

96

Q9BZP6
VSPFEMNFLGWIFVQ

ABCA13

4646

Q86UQ4
MNFLGWIFVQLASQG

ABCA13

4651

Q86UQ4
DTWNMFLNFTQVIGP

DCUN1D3

241

Q8IWE4
FSSGVFWMGLLFIPV

ATP8A1

1046

Q9Y2Q0
GQMVASPIFGLWSNY

MFSD8

86

Q8NHS3
SNWLGVMPYVIGFTS

OR8I2

141

Q8N0Y5
QSVNYLMGTWPFGTI

OPRM1

126

P35372
FVWQPGTLTQAATMG

MDN1

381

Q9NU22
QQTWFEGIFLSSMCP

ENTPD5

26

O75356
QRDMIIWSTQFNPGG

LRP1B

3931

Q9NZR2
LAWPGIMESFFTGQN

HERC2

1186

O95714
MPCGFIFQFQLLTSW

KATNIP

1396

O60303
IPDFQSGAMENWGLT

ERAP1

311

Q9NZ08
WGLAMGAFPSSVQIG

GRIA4

16

P48058
LVGSNVPWAFMQGEI

IRF2BPL

766

Q9H1B7
GLGWSLSPNFQITAM

FCRL5

236

Q96RD9
MASPNALVLWEAQFG

OGDHL

721

Q9ULD0
MWYNNSAGPFLLTGF

OR51B4

1

Q9Y5P0
FLLTGFSGMEQQYPW

OR51V1

21

Q9H2C8
LWNPMSIGISFMGNY

PGLYRP1

121

O75594
RPNVFWMTGFFNPQG

DNAH8

4341

Q96JB1
GPIPWFMVAEFFSQG

SLC2A2

416

P11168
GASVANFNLTFSWPM

LEPR

721

P48357
WQMFGPFGAVTNVKV

ELAVL1

261

Q15717
AWLGVFGFSAVPVFM

GPM6B

146

Q13491
FTSPGALPFISFMQW

NOC2L

346

Q9Y3T9
GSFSFFPVQMILTWL

PTPRO

336

Q16827
RGSPSLAMWLVNGFQ

TM7SF2

216

O76062
FGSGWPVTMFISFLL

FADS2B

191

A8MWK0
LPSLVFGISMAGWQV

SLC34A1

526

Q06495
SSWPQGFGQLTQLGM

ACP3

61

P15309
FVVGLPSNGMALWVF

F2RL1

86

P55085
AGLISPTGWNNVFYM

SLC37A2

451

Q8TED4
SNGMPVWQLLGFVTN

HIKESHI

61

Q53FT3
ELKAWQGMVPFVFVG

FMR1

391

Q06787
MQLWGSTSNDGAFPI

IGSF1

1011

Q8N6C5
FLVGVPGNAMVAWVA

C5AR2

46

Q9P296
GVNIICFQEAWTMPF

UPB1

111

Q9UBR1
TMAWGNFPAEKGQLF

CRTC2

146

Q53ET0
DNFQRGIFVWPMNFG

GALNT5

631

Q7Z7M9
TWFIMGILNPAQGFL

GPR143

291

P51810
MAQFPTPFGGSLDIW

ITSN1

1

Q15811
FISFLPIMQGWNNIG

HTR4

151

Q13639
VSVGLPNMTQGFWEN

ACE2

316

Q9BYF1
AMGWGFPIFLVTLVA

ADGRG1

521

Q9Y653
GSAPMHGFAIWFQVT

PRMT6

281

Q96LA8
ILWQMFGPFGAVTNV

ELAVL2

291

Q12926
MNTWIDSLQAFFPGL

EDEM1

431

Q92611
VPGGFLTAAVWMSFA

GPR85

316

P60893
WMSFAQAGINPFVCI

GPR85

326

P60893
FLVGALPWNGEFTVM

CST8

121

O60676
LFSQWAGPFSIMFTP

FRY

1126

Q5TBA9
SLWFPVGGFMQQGST

GRIK4

596

Q16099
TLGNSLWFPVGGFMQ

GRIK5

591

Q16478
LWFPVGGFMQQGSEI

GRIK5

596

Q16478
LIPQNGFWTLEMFGN

BTN2A2

411

Q8WVV5
VGVNPAWLTLGFMSS

SLC13A1

116

Q9BZW2
FGQGQEPLDMFFWVN

C3orf86

6

P0DN24
FMLQWNPFVDGANTG

MAP4K5

366

Q9Y4K4
GNTNAMKSFVLGWPT

ARHGAP20

146

Q9P2F6
GMNFTVGSNFSPWIV

RGS22

156

Q8NE09
WSVTVSMFPFGGFIG

SLC2A5

71

P22732
GFTLNTWFRMDPLNN

NBEA

256

Q8NFP9
QMTAGFLDWPQGTFA

ETFB

136

P38117
FMFLGISAVNPFIWT

SLC9A3

351

P48764
PQVWMDAGTQIFFSF

SLC6A12

281

P48065
VHLFGFWAFPMNPSG

ST8SIA5

316

O15466
WFPIILAMVISSFGG

SLC41A3

286

Q96GZ6
SWLVMFGFQLSNIIP

TENM2

2481

Q9NT68
AFQSWGSGPPRQFMD

SPATA31E1

1296

Q6ZUB1
GNDTMFLVTWQASGP

CLCA2

521

Q9UQC9
GLTQASFIYQMPAGW

C10orf55

91

Q5SWW7
NSQPLMTKLQWLFGF

USP35

476

Q9P2H5
PQVWMDAGTQIFFSF

SLC6A13

276

Q9NSD5
GLIATGMFQFWPHSI

EXT2

36

Q93063
FENFPGLWQNMTGLK

PIEZO2

756

Q9H5I5
GAVSWQPTNGIFLSM

TMEM168

371

Q9H0V1
FSLLWAGPMNAGVTQ

TRBV6-7

11

A0A0A0MS04
IFGSSWSVQPMFRNG

ATP6V0A4

476

Q9HBG4
QLPGGPFWSILFFFM

SLC6A14

401

Q9UN76
MRPFSQGILIFSQSW

SLFN5

411

Q08AF3
WGAPVTIFMGNVVSY

TRPM4

776

Q8TD43