Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	fused cornea and lens	CUBN SLC1A1 AGAP7P AGAP4 AGAP6	3.61e-07	24	89	5	MP:0001307
Domain	ARM-type_fold	DCAF1 RALGAPA1 CLTCL1 ZNFX1 CLHC1 THADA PSME4 PIK3CD PI4KA LTN1 PKP1	5.63e-06	339	111	11	IPR016024
Domain	Spectrin_repeat	SYNE1 DST KRT77 SYNE2	2.50e-05	29	111	4	IPR002017
Domain	AKAP_110	AKAP3 AKAP4	3.50e-05	2	111	2	IPR020799
Domain	AKAP_110	AKAP3 AKAP4	3.50e-05	2	111	2	SM00807
Domain	Spectrin/alpha-actinin	SYNE1 DST KRT77 SYNE2	3.74e-05	32	111	4	IPR018159
Domain	SPEC	SYNE1 DST KRT77 SYNE2	3.74e-05	32	111	4	SM00150
Domain	Clathrin_H-chain_linker	CLTCL1 CLHC1	1.05e-04	3	111	2	IPR012331
Domain	AKAP_110_C	AKAP3 AKAP4	1.05e-04	3	111	2	IPR018292
Domain	KASH	SYNE1 SYNE2	2.08e-04	4	111	2	PF10541
Domain	KASH	SYNE1 SYNE2	2.08e-04	4	111	2	IPR012315
Domain	SPHK1-interactor_AKAP_110	AKAP3 AKAP4	2.08e-04	4	111	2	IPR008382
Domain	Multidrug-R_assoc	ABCC6 ABCC2	2.08e-04	4	111	2	IPR005292
Domain	KASH	SYNE1 SYNE2	2.08e-04	4	111	2	PS51049
Domain	AKAP_110	AKAP3 AKAP4	2.08e-04	4	111	2	PF05716
Domain	KASH	SYNE1 SYNE2	2.08e-04	4	111	2	SM01249
Domain	Actinin_actin-bd_CS	SYNE1 DST SYNE2	3.32e-04	23	111	3	IPR001589
Domain	Spectrin	SYNE1 DST SYNE2	3.32e-04	23	111	3	PF00435
Domain	ACTININ_2	SYNE1 DST SYNE2	3.32e-04	23	111	3	PS00020
Domain	ACTININ_1	SYNE1 DST SYNE2	3.32e-04	23	111	3	PS00019
Domain	RII_binding_1	AKAP3 AKAP4	3.46e-04	5	111	2	PF10522
Domain	RII_binding_1	AKAP3 AKAP4	3.46e-04	5	111	2	IPR018459
Domain	Keratin_II	KRT4 KRT8 KRT77	4.81e-04	26	111	3	IPR003054
Domain	ArfGap	AGAP7P AGAP4 AGAP6	6.67e-04	29	111	3	SM00105
Domain	ArfGap	AGAP7P AGAP4 AGAP6	6.67e-04	29	111	3	PF01412
Domain	ARFGAP	AGAP7P AGAP4 AGAP6	6.67e-04	29	111	3	PS50115
Domain	ArfGAP	AGAP7P AGAP4 AGAP6	6.67e-04	29	111	3	IPR001164
Domain	NXPH/NXPE	NXPE4 NXPE1	9.57e-04	8	111	2	IPR026845
Domain	DHC_N1	DNAH2 DYNC1H1	9.57e-04	8	111	2	PF08385
Domain	Neurexophilin	NXPE4 NXPE1	9.57e-04	8	111	2	PF06312
Domain	Dynein_heavy_dom-1	DNAH2 DYNC1H1	9.57e-04	8	111	2	IPR013594
Domain	PI3Ka	PIK3CD PI4KA	1.23e-03	9	111	2	PF00613
Domain	-	PIK3CD PI4KA	1.23e-03	9	111	2	1.25.40.70
Domain	PI3Ka	PIK3CD PI4KA	1.23e-03	9	111	2	SM00145
Domain	PH	CERK PLEKHG4 PLEKHH1 ITSN2 AGAP7P AGAP4 AGAP6	1.37e-03	278	111	7	SM00233
Domain	PH_domain	CERK PLEKHG4 PLEKHH1 ITSN2 AGAP7P AGAP4 AGAP6	1.42e-03	280	111	7	IPR001849
Domain	PIK_HELICAL	PIK3CD PI4KA	1.53e-03	10	111	2	PS51545
Domain	PI_Kinase	PIK3CD PI4KA	1.53e-03	10	111	2	IPR015433
Domain	PInositide-3_kin_accessory_dom	PIK3CD PI4KA	1.53e-03	10	111	2	IPR001263
Domain	AAA+_ATPase	ABCA13 DNAH2 ABCC6 ABCC2 DYNC1H1	1.69e-03	144	111	5	IPR003593
Domain	AAA	ABCA13 DNAH2 ABCC6 ABCC2 DYNC1H1	1.69e-03	144	111	5	SM00382
Domain	Homeobox_metazoa	NKX2-6 BARX2 BARHL1 DLX4	2.04e-03	90	111	4	IPR020479
Domain	GrpE_coiled_coil	KRT4 KRT77	2.22e-03	12	111	2	IPR013805
Domain	Keratin_I	KRT4 KRT8 KRT77	2.27e-03	44	111	3	IPR002957
Domain	Homeobox	CUX2 NKX2-6 BARX2 BARHL1 TGIF2LX DLX4	2.75e-03	234	111	6	PF00046
Domain	HOMEOBOX_1	CUX2 NKX2-6 BARX2 BARHL1 TGIF2LX DLX4	2.87e-03	236	111	6	PS00027
Domain	ABC_tran	ABCA13 ABCC6 ABCC2	2.91e-03	48	111	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCA13 ABCC6 ABCC2	2.91e-03	48	111	3	PS50893
Domain	HOX	CUX2 NKX2-6 BARX2 BARHL1 TGIF2LX DLX4	2.93e-03	237	111	6	SM00389
Domain	Dynein_heavy_chain_D4_dom	DNAH2 DYNC1H1	3.04e-03	14	111	2	IPR024317
Domain	Dynein_HC_stalk	DNAH2 DYNC1H1	3.04e-03	14	111	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH2 DYNC1H1	3.04e-03	14	111	2	IPR013602
Domain	DHC_N2	DNAH2 DYNC1H1	3.04e-03	14	111	2	PF08393
Domain	MT	DNAH2 DYNC1H1	3.04e-03	14	111	2	PF12777
Domain	AAA_8	DNAH2 DYNC1H1	3.04e-03	14	111	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH2 DYNC1H1	3.04e-03	14	111	2	IPR011704
Domain	AAA_5	DNAH2 DYNC1H1	3.04e-03	14	111	2	PF07728
Domain	HOMEOBOX_2	CUX2 NKX2-6 BARX2 BARHL1 TGIF2LX DLX4	3.05e-03	239	111	6	PS50071
Domain	Homeobox_dom	CUX2 NKX2-6 BARX2 BARHL1 TGIF2LX DLX4	3.05e-03	239	111	6	IPR001356
Domain	ABC_TRANSPORTER_1	ABCA13 ABCC6 ABCC2	3.09e-03	49	111	3	PS00211
Domain	ABC_transporter-like	ABCA13 ABCC6 ABCC2	3.27e-03	50	111	3	IPR003439
Domain	DHC_fam	DNAH2 DYNC1H1	3.49e-03	15	111	2	IPR026983
Domain	Dynein_heavy_dom	DNAH2 DYNC1H1	3.49e-03	15	111	2	IPR004273
Domain	Dynein_heavy	DNAH2 DYNC1H1	3.49e-03	15	111	2	PF03028
Domain	PI3/4_kinase_CS	PIK3CD PI4KA	3.49e-03	15	111	2	IPR018936
Domain	-	PIK3CD PI4KA	3.98e-03	16	111	2	1.10.1070.11
Domain	PI3Kc	PIK3CD PI4KA	3.98e-03	16	111	2	SM00146
Domain	PI3/4_kinase_cat_dom	PIK3CD PI4KA	5.03e-03	18	111	2	IPR000403
Domain	PI3_PI4_kinase	PIK3CD PI4KA	5.03e-03	18	111	2	PF00454
Domain	PI3_4_KINASE_3	PIK3CD PI4KA	5.03e-03	18	111	2	PS50290
Domain	PI3_4_KINASE_1	PIK3CD PI4KA	5.03e-03	18	111	2	PS00915
Domain	PI3_4_KINASE_2	PIK3CD PI4KA	5.03e-03	18	111	2	PS00916
Domain	Homeobox_CS	CUX2 NKX2-6 BARX2 BARHL1 DLX4	5.08e-03	186	111	5	IPR017970
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	RALGAPA1 SYNE1 GRIA1 PI4KA PKP1 AGAP7P AGAP4 AGAP6 DYNC1H1	5.35e-07	281	118	9	28706196
Pubmed	GGAPs, a new family of bifunctional GTP-binding and GTPase-activating proteins.	AGAP7P AGAP4 AGAP6	3.15e-06	9	118	3	12640130
Pubmed	Transcriptional profiling of developing mouse epidermis reveals novel patterns of coordinated gene expression.	KRT4 KRT8 KRT77	3.15e-06	9	118	3	17330888
Pubmed	AGAP1/AP-3-dependent endocytic recycling of M5 muscarinic receptors promotes dopamine release.	AGAP7P AGAP4 AGAP6	4.49e-06	10	118	3	20664521
Pubmed	AGAP1, a novel binding partner of nitric oxide-sensitive guanylyl cyclase.	AGAP7P AGAP4 AGAP6	6.16e-06	11	118	3	15381706
Pubmed	CXCR4 and CXCR7 have distinct functions in regulating interneuron migration.	RELN CUX2 ACKR3	8.19e-06	12	118	3	21220099
Pubmed	The Endosome Localized Arf-GAP AGAP1 Modulates Dendritic Spine Morphology Downstream of the Neurodevelopmental Disorder Factor Dysbindin.	AGAP7P AGAP4 AGAP6	1.06e-05	13	118	3	27713690
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	1.14e-05	2	118	2	11792814
Pubmed	Glutamate transporter type 3 regulates mouse hippocampal GluR1 trafficking.	GRIA1 SLC1A1	1.14e-05	2	118	2	24412196
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	1.14e-05	2	118	2	24931616
Pubmed	[Mouse type II cytokeratin genes CK-4 and CK-8 mapped on chromosome 15].	KRT4 KRT8	1.14e-05	2	118	2	1722687
Pubmed	Polarized and functional epithelia can form after the targeted inactivation of both mouse keratin 8 alleles.	KRT4 KRT8	1.14e-05	2	118	2	1721911
Pubmed	Lack of AKAP3 disrupts integrity of the subcellular structure and proteome of mouse sperm and causes male sterility.	AKAP3 AKAP4	1.14e-05	2	118	2	31969357
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	1.14e-05	2	118	2	22768332
Pubmed	Pyruvate kinase L/R links metabolism dysfunction to neuroendocrine differentiation of prostate cancer by ZBTB10 deficiency.	PKLR ZBTB10	1.14e-05	2	118	2	35306527
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	1.14e-05	2	118	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	1.14e-05	2	118	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	1.14e-05	2	118	2	24586179
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	1.14e-05	2	118	2	17761684
Pubmed	Nucleotide sequence of mouse EndoA cytokeratin cDNA reveals polypeptide characteristics of the type-II keratin subfamily.	KRT4 KRT8	1.14e-05	2	118	2	2464527
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	1.14e-05	2	118	2	31578382
Pubmed	SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.	RELN SYNE1 SYNE2	1.35e-05	14	118	3	19874786
Pubmed	GTP-binding protein-like domain of AGAP1 is protein binding site that allosterically regulates ArfGAP protein catalytic activity.	AGAP7P AGAP4 AGAP6	1.35e-05	14	118	3	22453919
Pubmed	From the Cover: Indispensability of the glutamate transporters GLAST and GLT1 to brain development.	RELN GRIA1 SLC1A1	1.35e-05	14	118	3	16880397
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DCAF1 POLR1A PLEKHG4 NOL11 PFKL NCAPH SERPINH1 AP2M1 DST PSME4 PI4KA LTN1 ZBTB10 PKP1 NUP160 DYNC1H1	1.40e-05	1353	118	16	29467282
Pubmed	Proteomic characterization of the human sperm nucleus.	KRT4 KRT8 EVC2 SYNE1 AKAP3 AKAP4 DST PSME4 UGP2	1.96e-05	438	118	9	21630459
Pubmed	Congenital Hepatic Fibrosis Overview ─ RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	EVC2 KIF7 BBS10 CPLANE1	3.01e-05	52	118	4	20301743
Pubmed	Isolation and molecular characterization of AKAP110, a novel, sperm-specific protein kinase A-anchoring protein.	AKAP3 AKAP4	3.42e-05	3	118	2	10319321
Pubmed	A gene triplet in the mouse.	DPP6 PDGFRA	3.42e-05	3	118	2	5529676
Pubmed	Expression and localization of ATP binding cassette (ABC) family of drug transporters in gastric hepatoid adenocarcinomas.	ABCC6 ABCC2	3.42e-05	3	118	2	18439156
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	3.42e-05	3	118	2	16079285
Pubmed	The intersectin 2 adaptor links Wiskott Aldrich Syndrome protein (WASp)-mediated actin polymerization to T cell antigen receptor endocytosis.	ITSN2 PAK1	3.42e-05	3	118	2	11748279
Pubmed	Rifampicin induces clathrin-dependent endocytosis and ubiquitin-proteasome degradation of MRP2 via oxidative stress-activated PKC-ERK/JNK/p38 and PI3K signaling pathways in HepG2 cells.	AP2M1 ABCC2	3.42e-05	3	118	2	31316180
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	3.42e-05	3	118	2	10878022
Pubmed	Direct contact with endoderm-like cells efficiently induces cardiac progenitors from mouse and human pluripotent stem cells.	KRT8 PDGFRA	3.42e-05	3	118	2	23056302
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	3.42e-05	3	118	2	12408964
Pubmed	Homozygous loss-of-function mutations in FSIP2 cause male infertility with asthenoteratospermia.	AKAP3 AKAP4	3.42e-05	3	118	2	30745215
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	3.42e-05	3	118	2	17462627
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	3.42e-05	3	118	2	33472039
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	3.42e-05	3	118	2	25516977
Pubmed	Charting the molecular network of the drug target Bcr-Abl.	DCAF1 KRT4 KRT8 AP2M1 PIK3CD KRT77 DYNC1H1	3.62e-05	266	118	7	19380743
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	PLEKHG4 NPAS3 PFKL NCAPH KIF7 LIG4 PI4KA ZBTB40 ZBTB10 PKP1 NUP160 DYNC1H1	3.64e-05	857	118	12	25609649
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	DCAF1 KRT4 KLHL24 KRT8 POLR1A USP43 ICE1 PFKL KIF7 KRT77 PKLR PKP1 NUP160	3.84e-05	1005	118	13	19615732
Pubmed	RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers.	KRT4 KRT8 KRT77 CHST2	4.33e-05	57	118	4	31862882
Pubmed	Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.	STYXL2 PFKL PI4KA UBE3C	4.64e-05	58	118	4	31067491
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	POLR1A SYNE1 NOL11 PFKL SERPINH1 KIF7 DST PI4KA KRT77 SYNE2 PKP1 NUP160 DYNC1H1	4.65e-05	1024	118	13	24711643
Pubmed	A CRISPR-based screen for Hedgehog signaling provides insights into ciliary function and ciliopathies.	ABCA13 ICE1 DST KRT77 ZBTB10 PKP1 DYNC1H1	5.48e-05	284	118	7	29459677
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	RALGAPA1 SYNE1 POT1 PFKL DST SYNE2	5.96e-05	197	118	6	20811636
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SYNE1 SYNE2	6.82e-05	4	118	2	16648470
Pubmed	Rump white inversion in the mouse disrupts dipeptidyl aminopeptidase-like protein 6 and causes dysregulation of Kit expression.	DPP6 PDGFRA	6.82e-05	4	118	2	9811881
Pubmed	Genomic analysis of Meckel-Gruber syndrome in Arabs reveals marked genetic heterogeneity and novel candidate genes.	EVC2 CPLANE1	6.82e-05	4	118	2	23169490
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE1 SYNE2	6.82e-05	4	118	2	28716842
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SYNE1 SYNE2	6.82e-05	4	118	2	23071752
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SYNE1 SYNE2	6.82e-05	4	118	2	20108321
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	SYNE1 SYNE2	6.82e-05	4	118	2	19596800
Pubmed	A 1.8-Mb YAC contig spanning three members of the receptor tyrosine kinase gene family (Pdgfra, Kit, and Flk1) on mouse chromosome 5.	DPP6 PDGFRA	6.82e-05	4	118	2	7540588
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	DPP6 SLC1A1 AP2M1 PI4KA LRRTM4 AGAP7P AGAP4 AGAP6	7.57e-05	405	118	8	38187761
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 CERK ICE1 NCAPH DST PSME4 AGAP7P AGAP4 AGAP6	8.40e-05	529	118	9	14621295
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	KIF7 DST PSME4 LTN1 UBE3C NUP160	8.93e-05	212	118	6	33853758
Pubmed	The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.	DPP6 NPAS3 SLC34A2 SLC1A1 ACOX2 CHST2	8.93e-05	212	118	6	19521566
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	POLR1A SYNE1 NOL11 PFKL NCAPH SERPINH1 THADA AP2M1 PI4KA PKP1 UBE3C CHST2 NUP160 DYNC1H1 MGAM2	9.88e-05	1425	118	15	30948266
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT8 CUX2 CLTCL1 SYNE1 DNAH2 GRIA1 NCAPH LIG4 AP2M1 DST KRT77 SYNE2 ITSN2 UGP2 ABCC2	1.13e-04	1442	118	15	35575683
Pubmed	CABYR isoforms expressed in late steps of spermiogenesis bind with AKAPs and ropporin in mouse sperm fibrous sheath.	AKAP3 AKAP4	1.13e-04	5	118	2	20731842
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SYNE1 SYNE2	1.13e-04	5	118	2	22632968
Pubmed	Human spermatozoa contain multiple targets for protein S-nitrosylation: an alternative mechanism of the modulation of sperm function by nitric oxide?	AKAP3 AKAP4	1.13e-04	5	118	2	17683036
Pubmed	Detailed map of a region commonly amplified at 11q13-->q14 in human breast carcinoma.	SERPINH1 PAK1	1.13e-04	5	118	2	9533029
Pubmed	Paxillin-dependent paxillin kinase linker and p21-activated kinase localization to focal adhesions involves a multistep activation pathway.	PKLR PAK1	1.13e-04	5	118	2	12006652
Pubmed	A-kinase anchoring protein 4 binding proteins in the fibrous sheath of the sperm flagellum.	AKAP3 AKAP4	1.13e-04	5	118	2	12606363
Pubmed	Reelin signaling facilitates maturation of CA1 glutamatergic synapses.	RELN GRIA1	1.13e-04	5	118	2	17229826
Pubmed	Gene expression profiling of preplate neurons destined for the subplate: genes involved in transcription, axon extension, neurotransmitter regulation, steroid hormone signaling, and neuronal survival.	RELN SLC1A1	1.13e-04	5	118	2	19398467
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE1 SYNE2	1.13e-04	5	118	2	18396275
Pubmed	Vertebrate Dynein-f depends on Wdr78 for axonemal localization and is essential for ciliary beat.	DNAH2 DYNLT1	1.13e-04	5	118	2	30060180
Pubmed	CXCR7 prevents excessive CXCL12-mediated downregulation of CXCR4 in migrating cortical interneurons.	RELN ACKR3	1.13e-04	5	118	2	24718993
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	KRT8 DNAH2 SERPINH1 DST DYNC1H1	1.28e-04	142	118	5	30809309
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	KRT4 KRT8 SERPINH1 PSME4 PI4KA KRT77 LTN1 PKP1 CPLANE1	1.36e-04	564	118	9	21565611
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	RELN AP2M1 NOD1 DST UGP2 CPLANE1 DYNC1H1	1.42e-04	331	118	7	29199018
Pubmed	Mapping of QTLs for oral alcohol self-administration in B6.C and B6.I quasi-congenic RQI strains.	LRRTM4 TAS2R20 TAS2R19	1.45e-04	30	118	3	17273929
Pubmed	Expression and function of CXCR7 in the mouse forebrain.	RELN ACKR3	1.70e-04	6	118	2	20681075
Pubmed	Reelin signals through apolipoprotein E receptor 2 and Cdc42 to increase growth cone motility and filopodia formation.	RELN PAK1	1.70e-04	6	118	2	21048135
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SYNE1 SYNE2	1.70e-04	6	118	2	33058875
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE1 SYNE2	1.70e-04	6	118	2	18827015
Pubmed	In vitro reconstitution of a highly processive recombinant human dynein complex.	DYNLT1 DYNC1H1	1.70e-04	6	118	2	24986880
Pubmed	Expression of Cux-1 and Cux-2 in the subventricular zone and upper layers II-IV of the cerebral cortex.	RELN CUX2	1.70e-04	6	118	2	15452856
Pubmed	High-resolution genetic map and YAC contig around the mouse neurological locus reeler.	DPP6 RELN	1.70e-04	6	118	2	7894155
Pubmed	A high-resolution genetic map of mouse chromosome 5 encompassing the reeler (rl) locus.	DPP6 RELN	1.70e-04	6	118	2	7851897
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	DCAF1 SYNE1 ZNFX1 ACTL7B PKLR	1.76e-04	152	118	5	34299191
Pubmed	Large-scale proteomics and phosphoproteomics of urinary exosomes.	CUX2 PFKL CUBN SLC1A1 ITGB8 ITIH4 AP2M1 ITSN2 UGP2 PKLR SERPING1 DYNC1H1	1.81e-04	1016	118	12	19056867
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	DCAF1 KRT4 KRT8 RELN SERPINH1 DST DYNC1H1	2.37e-04	360	118	7	33111431
Pubmed	PDGFRα+ stromal adipocyte progenitors transition into epithelial cells during lobulo-alveologenesis in the murine mammary gland.	KRT8 PDGFRA	2.37e-04	7	118	2	30988300
Pubmed	Chemokine receptor CXCR7 non-cell-autonomously controls pontine neuronal migration and nucleus formation.	ACKR3 BARHL1	2.37e-04	7	118	2	32678266
Pubmed	Endocytosis of synaptic ADAM10 in neuronal plasticity and Alzheimer's disease.	GRIA1 AP2M1	2.37e-04	7	118	2	23676497
Pubmed	Molecular Dissection of Neuroligin 2 and Slitrk3 Reveals an Essential Framework for GABAergic Synapse Development.	GRIA1 SLITRK3	2.37e-04	7	118	2	29107521
Pubmed	The Secreted Glycoprotein Reelin Suppresses the Proliferation and Regulates the Distribution of Oligodendrocyte Progenitor Cells in the Embryonic Neocortex.	RELN PDGFRA	2.37e-04	7	118	2	32913108
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	KRT8 ABCA13 NXPE4 ICE1 ACOX2 SERPING1 CPLANE1	2.41e-04	361	118	7	26167880
Pubmed	A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.	SLC34A2 DYNLT1 SERPINH1 NOD1 SYNE2 LTN1 HSFX1	2.49e-04	363	118	7	25036637
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	SYNE1 DNAH2 NCAPH ITIH4 ADGB PI4KA SLC25A15 SYNE2 NUP160 DYNC1H1	2.57e-04	754	118	10	35906200
Pubmed	SUMOylation of DDX39A Alters Binding and Export of Antiviral Transcripts to Control Innate Immunity.	KLHL24 MYO1H NPAS3 NFKBIZ ITGB8 CLHC1 OPRL1 LIG4 SLC25A15 LRRTM4 TRIM38	2.92e-04	915	118	11	32393512
Pubmed	Epidermolysis Bullosa Simplex	KLHL24 DST	3.15e-04	8	118	2	20301543
Pubmed	Tissue distribution and hepatic and renal ontogeny of the multidrug resistance-associated protein (Mrp) family in mice.	ABCC6 ABCC2	3.15e-04	8	118	2	15802388
Pubmed	Pak1 and its T212 phosphorylated form accumulate in neurones and epithelial cells of the developing rodent.	KRT8 PAK1	3.15e-04	8	118	2	12950086
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	1.07e-04	4	77	2	1252
GeneFamily	NKL subclass homeoboxes and pseudogenes	NKX2-6 BARX2 BARHL1 DLX4	1.90e-04	67	77	4	519
GeneFamily	Keratins, type II	KRT4 KRT8 KRT77	2.02e-04	27	77	3	609
GeneFamily	ArfGAPs	AGAP7P AGAP4 AGAP6	3.70e-04	33	77	3	395
GeneFamily	Dyneins, cytoplasmic	DYNLT1 DYNC1H1	1.35e-03	13	77	2	538
GeneFamily	ATP binding cassette subfamily C	ABCC6 ABCC2	1.35e-03	13	77	2	807
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	PLEKHG4 PLEKHH1 AGAP7P AGAP4 AGAP6	1.86e-03	206	77	5	682
GeneFamily	X-linked mental retardation\|Rho GTPase activating proteins\|BAR-PH domain containing	AGAP4 AGAP6	2.34e-03	17	77	2	1291
GeneFamily	Ankyrin repeat domain containing	TRPV1 NFKBIZ AGAP7P AGAP4 AGAP6	3.72e-03	242	77	5	403
GeneFamily	Zinc fingers MYND-type\|A-kinase anchoring proteins	AKAP3 AKAP4	6.75e-03	29	77	2	396
ToppCell	Fibroblasts-CD55+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SLC1A1 ABCC6 ITGB8 ITIH4 UGP2 STEAP3 CHST2	7.19e-07	190	117	7	b4088128f5acf53f43244c9af9fe44e033f1a57a
ToppCell	control\|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KRT8 ABCA13 ITGB8 DST SYNE2 PKP1 CPLANE1	1.01e-06	200	117	7	97f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	KRT8 ABCA13 ITGB8 DST SYNE2 PKP1 CPLANE1	1.01e-06	200	117	7	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 ITIH4 ACOX2 PKLR SERPING1 ABCC2	5.50e-06	168	117	6	b98af4043dfa5dfa4413e482879fad88de484675
ToppCell	PND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CTNNAL1 SLC34A2 ABCC6 PLEKHH1 THADA DLX4	5.50e-06	168	117	6	08f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 ITIH4 ACOX2 PKLR SERPING1 ABCC2	5.50e-06	168	117	6	073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCell	droplet-Liver-HEPATOCYTES\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 ITIH4 ACOX2 PKLR SERPING1 ABCC2	5.69e-06	169	117	6	f195467438c589f87224bde7da720dea072d110c
ToppCell	droplet-Liver-HEPATOCYTES-1m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 ITIH4 ACOX2 PKLR SERPING1 ABCC2	5.69e-06	169	117	6	7785cab967a33560830c394c918d6ce625103858
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP6 CUBN SLC1A1 ITGB8 SYNE2 ABCC2	8.17e-06	180	117	6	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	droplet-Lung-nan-21m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 SLC34A2 BARX2 ITIH4 BARHL1 PKP1	8.70e-06	182	117	6	40539ade8c3cd12b61f1cd0d493828e58282796b
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ABCA13 CUBN SLC1A1 ITGB8 SYNE2 ABCC2	8.97e-06	183	117	6	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Calu_3-infected\|Calu_3 / Cell line, Condition and Strain	NFKBIZ ZNFX1 ITGB8 DST SYNE2 TRIM38	8.97e-06	183	117	6	8f7f5000645f24f20a8d7700c4df1f8953a1780b
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	ABCA13 SLC34A2 CUBN SLC1A1 ITGB8 SYNE2	9.26e-06	184	117	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN SLC1A1 ABCC6 ITGB8 SYNE2 TRIM38	1.08e-05	189	117	6	28b502611829e4a24caff2562545c7db97686099
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN SLC1A1 ABCC6 ITGB8 SYNE2 ABCC2	1.14e-05	191	117	6	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN SLC1A1 ABCC6 ITGB8 SYNE2 ABCC2	1.14e-05	191	117	6	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-oligodendrocyte_precursor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP6 PDGFRA SLITRK3 OPRL1 LRRTM4 MGAT5B	1.14e-05	191	117	6	ece87127f85939e61b1048d968ed96f0e87c3a79
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-Oligodendrocyte_progenitor_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPP6 PDGFRA SLITRK3 OPRL1 LRRTM4 MGAT5B	1.14e-05	191	117	6	478e8341ee03b05501e2233e02cef5f97492c95d
ToppCell	Fibroblasts-CD55+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	SLC1A1 ABCC6 ITGB8 ACKR3 DLX4 CHST2	1.21e-05	193	117	6	8f4bf9a2fbedae35432dad96730b00c70185874c
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	CERK EVC2 DST PIK3CD SERPING1 STEAP3	1.29e-05	195	117	6	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 UGP2 SERPING1 STEAP3	1.33e-05	196	117	6	ad1838dabd043cb140260843e3527d8c7d58850e
ToppCell	facs-Heart-LA-3m-Mesenchymal-fibroblast_of_cardiac_tissue\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 UGP2 SERPING1 STEAP3	1.33e-05	196	117	6	cbc15c0769016fe9972445169029bd8d14a7e6ef
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SYNE1 DNAH2 USP43 ADGB SYNE2 CPLANE1	1.36e-05	197	117	6	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	facs-Heart-LA-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 UGP2 SERPING1 STEAP3	1.36e-05	197	117	6	2a91738cb6d7588869dd00deeea0cbbc2d6aa34d
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PDGFRA GRIA1 COL6A5 SERPINH1 DST SERPING1	1.40e-05	198	117	6	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	(5)_Fibroblast-G\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	DPP6 PDGFRA GRIA1 COL6A5 DST SERPING1	1.44e-05	199	117	6	b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	DPP6 PDGFRA GRIA1 COL6A5 DST SERPING1	1.44e-05	199	117	6	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	DPP6 PDGFRA GRIA1 COL6A5 DST SERPING1	1.44e-05	199	117	6	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPP6 PDGFRA GRIA1 COL6A5 DST SERPING1	1.44e-05	199	117	6	212e89d097753790061310373a1fafba773488b6
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DPP6 PDGFRA GRIA1 COL6A5 DST SERPING1	1.44e-05	199	117	6	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Lamp5-Lamp5_Fam19a1_Pax6\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KRT4 RELN NDST4 NPAS3 NOD1	1.71e-05	121	117	5	7f2057367777c6c92f596054cbc5fe567d079fbc
ToppCell	COVID-19-kidney-Technical/muscle_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	RELN CUX2 ABCA13 DNAH2 LRRTM4	4.20e-05	146	117	5	c55f1bdb6ac43b4118cb27ea7c879527e1afcbab
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	TRPV1 CLTCL1 BARX2 NCAPH ACOX2	5.76e-05	156	117	5	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	RALGAPA1 DPP6 PSME4 SYNE2 LRRTM4	5.76e-05	156	117	5	1545169694f686d28648a68b552c2ae606599d66
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)\|390C / Donor, Lineage, Cell class and subclass (all cells)	KRT8 USP43 SLC34A2 ITIH4 PLEKHH1	6.49e-05	160	117	5	731def6d82814ebac1a400bc7aea5f6da43ec960
ToppCell	390C-Epithelial_cells-Epithelial-A_(AT2)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	KRT8 USP43 SLC34A2 ITIH4 PLEKHH1	6.49e-05	160	117	5	cf27b4ac4d0caa6f9b068dc8ea93472470a01a4d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	EVC2 NOL11 NFKBIZ SYNE2 ZBTB10	6.89e-05	162	117	5	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	E16.5-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Deuterosomal-Deuterosomal_G2M\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT4 KRT8 USP43 ACOX2 AKAP4	7.30e-05	164	117	5	d9531848105d606adedde65426177cf851140e31
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA13 BARX2 ACKR3 PAK1 PKP1	8.18e-05	168	117	5	6521bead9789d626b86cbd08692c621c5a5aef33
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA13 BARX2 ACKR3 PAK1 PKP1	8.41e-05	169	117	5	c3ee781735a9288ce1822b230d39bb91c1415589
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KRT8 BARX2 ACOX2 ADGB BARHL1	9.39e-05	173	117	5	a809be2630d2b91b53b82b5e2bb99e05524597c1
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_3\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	KRT4 KRT8 ABCA13 ITGB8 PKP1	9.64e-05	174	117	5	9e5fae9ecc7c0111fc8a252e72b89dc89c0d3a7c
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OTOA KRT8 PDGFRA SERPINH1 SERPING1	9.64e-05	174	117	5	68a6ed81e7e1f95b61f7ee20403980fa3a8db4d0
ToppCell	droplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITIH4 ACOX2 PKLR SERPING1 ABCC2	9.91e-05	175	117	5	5c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA13 SYNE1 NFKBIZ SYNE2 MGAT5B	9.91e-05	175	117	5	cf53a15bfb37b6019e7052ffdf594a9ac040900e
ToppCell	facs-Trachea-nan-18m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT4 KRT8 BARX2 KRT77 PKP1	9.91e-05	175	117	5	eb87275da6f61ecb4fbc89421dfd27bead1e0f48
ToppCell	facs-Trachea-nan-18m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT4 KRT8 BARX2 KRT77 PKP1	9.91e-05	175	117	5	3883675a726dd0c6c3a7113d59be2a093ea2dc6f
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	DPP6 GRIA1 COL6A5 DST SERPING1	1.05e-04	177	117	5	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKL4 BARX2 ACOX2 ADGB BARHL1	1.05e-04	177	117	5	d947ba38db1772fc5fdcdc211f7511c4aa699dee
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	DPP6 GRIA1 COL6A5 DST SERPING1	1.05e-04	177	117	5	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	droplet-Lung-21m-Epithelial-airway_epithelial-lung_ciliated_cell-ciliated_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CDKL4 BARX2 ACOX2 ADGB BARHL1	1.05e-04	177	117	5	d5640f0097878f0dac671e51dc51310278bb2682
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUX2 GRIA1 ACOX2 ADGB PKLR	1.07e-04	178	117	5	58857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP6 RELN NPAS3 ITGB8 SYNE2	1.07e-04	178	117	5	544379f5a6145429762258d426b876bb36c112f5
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUX2 GRIA1 ACOX2 ADGB PKLR	1.07e-04	178	117	5	8b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CUX2 GRIA1 ACOX2 ADGB PKLR	1.07e-04	178	117	5	b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	OTOA DYNLT1 ZNFX1 NOD1 TRIM38	1.10e-04	179	117	5	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA13 CUBN SLC1A1 ABCC6 ITGB8	1.10e-04	179	117	5	58ae5a97fe2a14e1c6fdeb886397eb06fdaf0428
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DNAH2 USP43 CLHC1 ADGB HSFX1	1.13e-04	180	117	5	92fb01b91261b3103454924cde56add337b41844
ToppCell	droplet-Limb_Muscle-Pre-Sort\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 CTNNAL1 MYO1H DST SERPING1	1.13e-04	180	117	5	af2bafcd1b2082629de3ea336711add01565c4c4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KRT8 CTNNAL1 MYO1H DST SERPING1	1.13e-04	180	117	5	f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ABCA13 USP43 SLC34A2 NFKBIZ PUS7	1.16e-04	181	117	5	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	Basal\|World / shred by cell class for mouse tongue	KLHL24 CTNNAL1 SERPINH1 DST ACKR3	1.22e-04	183	117	5	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	droplet-Fat-Scat-21m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA COL6A5 SERPINH1 ACKR3 SERPING1	1.29e-04	185	117	5	01bbe1e09f9ccae837a03ea2cdd168fa10800942
ToppCell	COVID-19-kidney-Mito-rich_PCT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CUBN SLC1A1 ITGB8 SYNE2 ABCC2	1.29e-04	185	117	5	1bbc2ba8a20f72f61981b1301cdd6018cdd9150d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KRT8 ABCA13 SLC34A2 NFKBIZ SERPING1	1.32e-04	186	117	5	3dae539cce15fcf2b1b32e981d7febe94c03c600
ToppCell	5'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RELN CTNNAL1 ITGB8 DST LRRTM4	1.32e-04	186	117	5	6f88b68735d0f7c9904eb8413e6007910d556185
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SLC34A2 CUBN SYNE2 ABCC2 TRIM38	1.32e-04	186	117	5	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CUX2 USP43 LRRTM4 PAK1 MGAT5B	1.35e-04	187	117	5	f18628ffc7ff7c762b8339ba8822cf0c3157f469
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DPP6 RELN NPAS3 PIK3CD ECE2	1.35e-04	187	117	5	85f1678338a47d91e296f0620d4887f057eb7e70
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN SLC1A1 ABCC6 SYNE2 ABCC2	1.35e-04	187	117	5	dcf6475ece5b34d9d58a0d1f51c18acedb19c119
ToppCell	COVID-19-kidney-tDL\|kidney / Disease (COVID-19 only), tissue and cell type	CUBN SLC1A1 ITGB8 ABCC2 TRIM38	1.35e-04	187	117	5	d35d27ca3c0e65f92f4508e1cb98a743f44fdcdf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN SLC1A1 ABCC6 SYNE2 ABCC2	1.35e-04	187	117	5	f1356273bd3587b6883295edf15cb9cdb706c057
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DPP6 CUBN ITGB8 SYNE2 ABCC2	1.35e-04	187	117	5	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	droplet-Fat-Scat-21m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA COL6A5 SERPINH1 ACKR3 SERPING1	1.39e-04	188	117	5	e54e09d34e263d5709c337914809e61e74e20591
ToppCell	droplet-Fat-Scat-21m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA COL6A5 SERPINH1 ACKR3 SERPING1	1.39e-04	188	117	5	7fc9810ab14354cb512e2b1285562009c10203f5
ToppCell	droplet-Marrow-nan-3m-Lymphocytic-naive_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERK DTWD1 PAK1 PUS7 ECE2	1.39e-04	188	117	5	e079a3873cf442e98ff41a240c80b80995aace11
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA ACKR3 UGP2 SERPING1 STEAP3	1.39e-04	188	117	5	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA GRIA1 SERPINH1 SERPING1 CHST2	1.42e-04	189	117	5	32e6d6285b258831b965281224ff2aaeecdcb5f5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN SLC1A1 ABCC6 ITGB8 ABCC2	1.42e-04	189	117	5	204ab61ae606b2d9be0cb6bf6a83a011740693a8
ToppCell	droplet-Limb_Muscle-nan-24m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA ACKR3 UGP2 SERPING1 STEAP3	1.42e-04	189	117	5	6e52cac679e0541ca5f2be316bdabdbc34da6e18
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 SERPING1 STEAP3	1.42e-04	189	117	5	bc54ffd7bd1627a36747a80ce5139e4a69928400
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CUBN SLC1A1 ABCC6 ITGB8 ABCC2	1.42e-04	189	117	5	13fd07cc408a9486f61a7b2c3a132c52d14b438d
ToppCell	COVID-19-kidney-PCT-S2\|kidney / Disease (COVID-19 only), tissue and cell type	CUBN SLC1A1 ITGB8 SYNE2 ABCC2	1.42e-04	189	117	5	0be5c669b6b308bd98ddb70c84877c62a6244bbd
ToppCell	droplet-Lung-LUNG-1m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA GRIA1 SERPINH1 SERPING1 CHST2	1.42e-04	189	117	5	385ef7bbd76c8047aeecf6542377d4213b5da5db
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	KRT8 ABCA13 SLC34A2 NFKBIZ ITGB8	1.42e-04	189	117	5	bd91bdfe35294e60d980259b70fe9e60dca2743f
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 SERPING1 STEAP3	1.46e-04	190	117	5	f3ca94a31a35eed5fecf3c4b8c957e1bc4150158
ToppCell	droplet-Mammary_Gland-nan-21m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 SERPING1 STEAP3	1.46e-04	190	117	5	c2cd1eb674162ee40502c3380b7245c85079c7ce
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 SERPING1 STEAP3	1.46e-04	190	117	5	47077579496c5340e99f61499427a3a36b566da3
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-Cd34+\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA COL6A5 SERPINH1 SERPING1 STEAP3	1.49e-04	191	117	5	6cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCell	droplet-Fat-Gat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA COL6A5 SERPINH1 SERPING1 STEAP3	1.49e-04	191	117	5	850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 SERPING1 STEAP3	1.49e-04	191	117	5	a57cf0519d749febc0b69fe0b098b7ba53d63258
ToppCell	droplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA COL6A5 SERPINH1 SERPING1 STEAP3	1.49e-04	191	117	5	8b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	ITGB8 ACKR3 UGP2 PKP1 DLX4	1.49e-04	191	117	5	5ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERK KLHL24 RELN LIG4 PSME4	1.49e-04	191	117	5	318323a12029a7992f16382cb0c186f5b2e1ca47
ToppCell	droplet-Mammary_Gland-nan-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDGFRA SERPINH1 ACKR3 SERPING1 STEAP3	1.49e-04	191	117	5	19c67a812b8ce97472d316acd15aeefe8736000d
ToppCell	PND07-Epithelial-Epithelial_Airway\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KRT4 KRT8 CDKL4 ADGB PKP1	1.49e-04	191	117	5	b55500eb416f4f339031acad16b2737e5b891d8e
ToppCell	facs-Marrow-B-cells-3m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CERK KLHL24 RELN LIG4 PSME4	1.49e-04	191	117	5	4aa29337f4d2528577bb90dc4abfb6eab93e120f
ToppCell	facs-Trachea-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDGFRA SERPINH1 UGP2 SERPING1 STEAP3	1.53e-04	192	117	5	321850b0f881420c2d57d3e825e365c82fa511ab
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDGFRA SERPINH1 ACKR3 SERPING1 STEAP3	1.53e-04	192	117	5	fc940f91ff8e051631dbf25e6e8d73cf8337eccb
ToppCell	facs-Trachea-24m-Mesenchymal-fibroblast-fibroblast_of_trachea\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PDGFRA SERPINH1 ACKR3 SERPING1 STEAP3	1.53e-04	192	117	5	7a2e79490e4f7058bb76b46c45b5df9f729e3146
Computational	Neighborhood of LCAT	ABCC6 ITIH4 ACOX2 HPR PKLR SERPING1	8.29e-05	124	63	6	GNF2_LCAT
Drug	plakin	KRT8 PLEKHG4 SYNE1 ACTL7B DST SYNE2 DYNC1H1	1.94e-07	82	115	7	CID000018752
Drug	AC1L1A5Z	KRT4 GRIA1 PFKL ABCC6 UGP2 PKLR SERPING1	1.54e-06	111	115	7	CID000000850
Disease	Intellectual Disability	RALGAPA1 CUX2 SYNE1 GRIA1 BRWD3 KIF7 AP2M1 UGP2 ZBTB40 ELP2 DYNC1H1 PUS7	1.29e-07	447	111	12	C3714756
Disease	cerebral palsy (implicated_via_orthology)	AGAP7P AGAP4 AGAP6	6.10e-06	10	111	3	DOID:1969 (implicated_via_orthology)
Disease	Bipolar Disorder	RELN CUX2 ABCA13 SYNE1 NPAS3 GRIA1 PFKL SLC1A1 ITIH4	8.23e-05	477	111	9	C0005586
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	8.37e-05	4	111	2	cv:CN293514
Disease	Microcephaly	NCAPH LIG4 DYNC1H1 PUS7	1.21e-04	67	111	4	C0025958
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.39e-04	5	111	2	C1450051
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	1.39e-04	5	111	2	C0410190
Disease	ficolin-2 measurement	NXPE4 NXPE1	1.39e-04	5	111	2	EFO_0008135
Disease	SUN domain-containing protein 3 measurement	NXPE4 NXPE1	1.39e-04	5	111	2	EFO_0802102
Disease	Liver Cirrhosis, Experimental	CERK KRT8 TRPV1 PDGFRA NFKBIZ SERPINH1 ACOX2 PLEKHH1 ACKR3 PKLR ABCC2	1.65e-04	774	111	11	C0023893
Disease	intellectual disability (implicated_via_orthology)	NDST4 ITSN2 ELP2 PUS7	1.88e-04	75	111	4	DOID:1059 (implicated_via_orthology)
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	2.08e-04	6	111	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	2.08e-04	6	111	2	C0410189
Disease	liver cirrhosis (is_marker_for)	KRT8 RELN SERPINH1 ITIH4	2.65e-04	82	111	4	DOID:5082 (is_marker_for)
Disease	epidermolysis bullosa simplex (is_implicated_in)	KLHL24 DST	2.91e-04	7	111	2	DOID:4644 (is_implicated_in)
Disease	OROFACIODIGITAL SYNDROME VI	KIF7 CPLANE1	2.91e-04	7	111	2	C2745997
Disease	Morphine Abuse	GRIA1 OPRL1	2.91e-04	7	111	2	C0600272
Disease	Morphine Dependence	GRIA1 OPRL1	2.91e-04	7	111	2	C0026552
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	2.91e-04	7	111	2	C0751337
Disease	Autistic behavior	CUX2 AP2M1	3.87e-04	8	111	2	C0856975
Disease	pancreatic carcinoma	DPP6 KRT8 SLC1A1 DST ACKR3	5.21e-04	174	111	5	EFO_0002618
Disease	colorectal cancer, endometrial neoplasm	NPAS3 SERPINH1 MGAT5B	5.34e-04	42	111	3	EFO_0004230, MONDO_0005575
Disease	indoleacetate measurement	ACKR3 LRRTM4	6.19e-04	10	111	2	EFO_0021015
Disease	cleft lip	SYNE1 GRIA1 ICE1 THADA DST MGAM2	7.34e-04	284	111	6	EFO_0003959
Disease	Ciliopathies	EVC2 KIF7 BBS10 CPLANE1	8.06e-04	110	111	4	C4277690
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	9.03e-04	12	111	2	DOID:11726 (implicated_via_orthology)
Disease	congenital diaphragmatic hernia (implicated_via_orthology)	PDGFRA KIF7	9.03e-04	12	111	2	DOID:3827 (implicated_via_orthology)
Disease	Polydactyly	EVC2 KIF7 BBS10 CPLANE1	1.01e-03	117	111	4	C0152427
Disease	Malformations of Cortical Development	SLC1A1 DYNC1H1	1.24e-03	14	111	2	C1955869
Disease	trimethylamine-N-oxide measurement	CUBN UBE3C	1.24e-03	14	111	2	EFO_0010541
Disease	total brain volume change measurement	DPP6 LRRTM4	1.24e-03	14	111	2	EFO_0021504
Disease	bone mineral accretion measurement, response to corticosteroid	DPP6 ACKR3	1.24e-03	14	111	2	EFO_0007591, GO_0031960
Disease	Cortical Dysplasia	SLC1A1 DYNC1H1	1.24e-03	14	111	2	C0431380
Disease	mannan-binding lectin serine protease 1 measurement	NXPE4 NXPE1	1.43e-03	15	111	2	EFO_0008223
Disease	Seizures	CUX2 SLC1A1 AP2M1 UGP2 ABCC2	1.43e-03	218	111	5	C0036572
Disease	Bardet-Biedl syndrome 1 (disorder)	KIF7 BBS10	1.84e-03	17	111	2	C2936862
Disease	sphingomyelin 14:0 measurement	THADA SYNE2	1.84e-03	17	111	2	EFO_0010390
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	GRIA1 AP2M1	1.84e-03	17	111	2	DOID:0060307 (is_implicated_in)
Disease	Profound Mental Retardation	KIF7 ZBTB40 ELP2 DYNC1H1	1.91e-03	139	111	4	C0020796
Disease	Mental Retardation, Psychosocial	KIF7 ZBTB40 ELP2 DYNC1H1	1.91e-03	139	111	4	C0025363
Disease	Mental deficiency	KIF7 ZBTB40 ELP2 DYNC1H1	1.91e-03	139	111	4	C0917816
Disease	aspartate aminotransferase measurement	KRT4 DPP6 KRT8 CUX2 DNAH2 CUBN ACOX2 HPR ABCC2 NUP160	2.20e-03	904	111	10	EFO_0004736
Disease	type 1 diabetes mellitus	CUX2 DNAH2 ITGB8 PI4KA ITSN2	2.25e-03	242	111	5	MONDO_0005147
Disease	colorectal cancer, inflammatory bowel disease	PTCHD3 DTWD1	2.30e-03	19	111	2	EFO_0003767, MONDO_0005575
Disease	melanoma	ZNF438 PDGFRA POT1 CUBN PAK1	2.51e-03	248	111	5	C0025202
Disease	Familial aplasia of the vermis	KIF7 CPLANE1	2.55e-03	20	111	2	cv:C0431399
Disease	disease of metabolism (implicated_via_orthology)	PFKL PKLR	2.81e-03	21	111	2	DOID:0014667 (implicated_via_orthology)
Disease	progression free survival, ovarian serous carcinoma	ABCA13 SLC1A1	3.08e-03	22	111	2	EFO_0004920, EFO_1001516
Disease	testosterone measurement	ZNF438 DPP6 CUX2 POLR1A DNAH2 USP43 OPRL1 THADA SYNE2 ZBTB10 TRIM38 NUP160	3.09e-03	1275	111	12	EFO_0004908
Disease	Epilepsy, Benign Psychomotor, Childhood	TRPV1 SLC1A1	3.37e-03	23	111	2	C0393672
Disease	Epilepsy, Lateral Temporal	TRPV1 SLC1A1	3.37e-03	23	111	2	C0393682
Disease	Uncinate Epilepsy	TRPV1 SLC1A1	3.37e-03	23	111	2	C0014558
Disease	Epilepsy, Temporal Lobe	TRPV1 SLC1A1	3.37e-03	23	111	2	C0014556
Disease	pyruvate measurement	PTCHD3 NPAS3 PFKL PKLR UBE3C	3.49e-03	268	111	5	EFO_0010117
Disease	low density lipoprotein cholesterol measurement, response to escitalopram, response to citalopram	DPP6 RELN	3.67e-03	24	111	2	EFO_0004611, EFO_0006329, EFO_0007871

Protein segments in the cluster

Peptide	Gene	Start	Entry
WVQAIQSQILASLQS	AGAP4	411	Q96P64
AWNQTTVIHLQAAKV	ACOX2	531	Q99424
WNSQSSIDQKLASQI	ERVK-18	401	O42043
ILASLQAFQQLWVSK	ACTL7B	386	Q9Y614
NLSQNSLSKKSLNVW	C2orf69	196	Q8N8R5
STNSLQKQLQAVLQW	AKAP4	766	Q5JQC9
NISVADTLQKVWAVL	ADGB	936	Q8N7X0
GVIKSVLWQTLQALN	CDKL4	101	Q5MAI5
LAASLNLTDTQVKTW	BARHL1	211	Q9BZE3
FVQWQQGSLLQKTLT	ABCA13	356	Q86UQ4
TTVITAVNNFLLKVW	BRWD3	436	Q6RI45
LSFQLNLKTNTVINW	CUX2	1201	O14529
WKFISQALLTFQTQI	BBS10	126	Q8TAM1
AAQLGLTQTQVKIWF	DLX4	151	Q92988
WVQAIQSQILASLQS	AGAP6	411	Q5VW22
NQLVDALTTWQNKTK	ITIH4	196	Q14624
ASALQLTSTQVKIWF	NKX2-6	166	A6NCS4
NLTVNTSWQKKSAFT	ITSN2	866	Q9NZM3
TKWSLLQQQKTARSN	KRT8	121	P05787
LWLKNQVQASSLDIN	LTN1	901	O94822
CLSVWNIKFQTLQTS	NOL11	286	Q9H8H0
LNQVSGWAKSQVIIL	OTOA	431	Q7RTW8
SWTILANNVSNIITE	PDGFRA	461	P16234
WNVVQSNNGIKVLLS	DCAF1	726	Q9Y4B6
SLNTVQVSWLNPVVV	NFKBIZ	231	Q9BYH8
SNKLTNISQETVNAW	LRRTM4	286	Q86VH4
NISQETVNAWISLIS	LRRTM4	291	Q86VH4
QIQRKNSSTVIWDSQ	MGAM2	1051	Q2M2H8
NNIENLISTLKQWRS	DST	1206	Q03001
ATLINEQWLLTTAKN	HPR	131	P00739
ETKWNLLQQQTTTTS	KRT4	166	P19013
LNNYLIWNLVQKTTS	ECE2	431	P0DPD6
LTAQWALAAQRLAQK	MGAT5B	261	Q3V5L5
KQANWLSVSNIIQLG	PFKL	66	P17858
ATASEWRLAQAQQKI	KIF7	696	Q2M1P5
WNLFQQISVKASSVV	PI4KA	676	P42356
LWLIQNQITAKGTAQ	NOD1	901	Q9Y239
QTARIWLLVNNTKTT	EVC2	181	Q86UK5
WLLVNNTKTTSSANL	EVC2	186	Q86UK5
NISSLQLRSWVSKSQ	PKLR	6	P30613
QQNKSIQSLTLEWNS	LRRC45	111	Q96CN5
VLSNALNITQTLNWL	ABCC2	1241	Q92887
SNIWLAAVTKQNVNA	AP2M1	61	Q96CW1
LVNFVQSWTNLKLQT	NDST4	536	Q9H3R1
SSQISWCLLNVNLSK	MDS2	26	Q8NDY4
NSVNSSSWKRITIQL	RELN	3181	P78509
EQWARLLQTSNITKS	PAK1	101	Q13153
QVILQWNSNKIKSSS	ITGB8	706	P26012
QQVKITVWALQLTSQ	CUBN	3316	O60494
IQALNTWEVNKVTTS	ICE1	426	Q9Y2F5
NSQLNIWIRVASLNK	KLHL24	381	Q6TFL4
ELQQLISVWIQAQSK	CTNNAL1	356	Q9UBT7
LLQLITQSSALEQKW	LIG4	171	P49917
KVASVVRDQNLSNVW	CPLANE1	986	Q9H799
SAKQTRQKVAVNWTN	FAM193B	876	Q96PV7
QSVLWVKQQRCAVSL	CERK	11	Q8TCT0
LAQSLGLTQLQVKTW	BARX2	166	Q9UMQ3
NSLTKTQWKTQIQNV	COL6A5	1061	A8TX70
QWTTNVVEQTLSQLT	DYNLT1	41	P63172
ANSVVVWVNIQAKTT	ACKR3	61	P25106
WVQAIQSQILASLQS	AGAP7P	411	Q5VUJ5
QTFITWTQKNRLVQA	DUXB	106	A0A1W2PPF3
LINTWVAKNTNNKIS	SERPING1	261	P05155
QAQLVVLSAQIAWSE	DYNC1H1	1746	Q14204
IILWNTTSWKQVQNL	ELP2	596	Q6IA86
STKVAVTWLNRAQNV	DPP6	391	P42658
AEKNWQVTAVNILTT	GRIA1	166	P42261
VALQNIAKTWDVTQL	DNAH2	1366	Q9P225
KIIFIDSTWNQTNKI	DTWD1	201	Q8N5C7
KNNWVLLSTVAAVVL	SLC1A1	16	P43005
AWQVNKTLNLSSISF	PTCHD3	271	Q3KNS1
IISQNFTKLWSALNL	NXPE1	26	Q8N323
VRTSSKAQAVNVAIW	OPRL1	161	P41146
KAQAVNVAIWALASV	OPRL1	166	P41146
IQKQLTGLLWNLSST	PKP1	346	Q13835
QKLWRLVSSNQFSSI	HSFX1	101	Q9UBD0
ITSTWNLRTQQSKLV	TAS2R19	246	P59542
SNLKVIIFISNAWAV	TAS2R20	76	P59543
QNVNDTLSRSWAVKL	TRIM38	246	O00635
LSEKTNLSLLQISNW	TGIF2LX	86	Q8IUE1
LQKLSLNSLQLVSEW	THADA	931	Q6YHU6
LWTGKQVVSTLLINI	POLR1A	681	O95602
QFSALLKTWAQQLTL	SYNE1	2971	Q8NF91
QSLASWTQNLKELQT	SYNE2	5856	Q8WXH0
VFQNSTKVWSALNLS	NXPE4	26	Q6UWF7
VSAALQVTQTLQWVV	ABCC6	1206	O95255
VLQASSLAIKQAWTA	PLEKHG4	1006	Q58EX7
KEWALAVSSSQLNTI	SLITRK3	816	O94933
SIQNLNSLVDKTSWI	POT1	511	Q9NUX5
DTSIKNQTQLNTTWL	PUS7	646	Q96PZ0
KRSALQSINEWAAQT	SERPINH1	166	P50454
IWIQSSATIAINAKN	NPAS3	406	Q8IXF0
AWLAANQLSSVITTK	NUP160	1266	Q12769
IAKSQNTVWSVIKSI	SLC25A15	146	Q9Y619
WTDIQQKIATQSQIT	SPICE1	221	Q8N0Z3
KQLQAVLQWVAASEL	AKAP3	771	O75969
AVWSQLAQAQLQKDL	CLTCL1	1106	P53675
QRLQIISQALSSWVK	CLHC1	236	Q8NHS4
NAWRTALTFQQIKQV	CHST2	481	Q9Y4C5
TILTKSTLENQNWRA	NCAPH	491	Q15003
IWCKTFTNKTQINVT	SLC34A2	301	O95436
IFNTNNLWISLAAVK	UGP2	326	Q16851
AVSWAQLQQSILSKV	USP43	426	Q70EL4
QNLVWLGLSISKSVI	ZNF542P	6	Q5EBM4
FQTLIVAWIKANLNV	RALGAPA1	621	Q6GYQ0
TVVKAFNVISAWTLQ	STEAP3	141	Q658P3
QLGIVKFLLQNSWQT	TRPV1	261	Q8NER1
DTISIASIQNWIANV	STYXL2	716	Q5VZP5
ASIQNWIANVVSETL	STYXL2	721	Q5VZP5
WIANVVSETLAQKQN	STYXL2	726	Q5VZP5
VSRNANLSTIKQLLW	PIK3CD	36	O00329
NTLLTWKANTTSNKE	TTC23L	141	Q6PF05
LVLQVLKQTARSSSW	PSME4	1641	Q14997
QLSSKENALVWIAVN	PLEKHH1	1236	Q9ULM0
KIVQALLTNESVWQI	ZNFX1	631	Q9P2E3
IKSIQSEQINAVAWT	TTC37	851	Q6PGP7
QKIASFWATRNLTNL	ZBTB10	496	Q96DT7
KLWAILNTVSNQGVI	ZNF438	806	Q7Z4V0
VNAIIKNQDITAWQS	ZNF285	126	Q96NJ3
KNQDITAWQSLTQVL	ZNF285	131	Q96NJ3
TLSATAIWQLLLVVQ	ZBTB40	526	Q9NUA8
TKQQTNTLLNLVWRD	UBE3C	401	Q15386
VLQTKWELLQQVNTS	KRT77	191	Q7Z794
TWLVNKINSSLVNKV	MYO1H	356	Q8N1T3
QDSTQTTTQKAWLVA	NACA2	41	Q9H009