Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

NALCN SCN1A SCN2A SCN3A CACNA1H

1.43e-06261535GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

CPS1 SCN1A SCN2A SCN3A

4.34e-05261534GO:0031420
GeneOntologyMolecularFunctionsodium channel activity

NALCN SCN1A SCN2A SCN3A CACNA1H

4.81e-05521535GO:0005272
GeneOntologyMolecularFunctionchannel activity

CACNA1C CACNA1F CACNA2D2 GRID1 RYR2 RYR3 NALCN SCN1A SCN2A SCN3A TMEM150C CACNA1H GJC3 GABRR3

5.37e-0552515314GO:0015267
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1C CACNA1F CACNA2D2 GRID1 RYR2 RYR3 NALCN SCN1A SCN2A SCN3A TMEM150C CACNA1H GABRR3

5.46e-0545915313GO:0005216
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1C CACNA1F CACNA2D2 GRID1 RYR2 RYR3 NALCN SCN1A SCN2A SCN3A TMEM150C CACNA1H GJC3 GABRR3

5.48e-0552615314GO:0022803
GeneOntologyMolecularFunctiongated channel activity

CACNA1C CACNA1F CACNA2D2 GRID1 RYR2 RYR3 SCN1A SCN2A TMEM150C CACNA1H GABRR3

5.49e-0533415311GO:0022836
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN3A

1.51e-04141533GO:0031402
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1C CACNA1F CACNA1H

1.51e-04141533GO:0008331
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 NALCN SCN1A SCN2A SCN3A CACNA1H

3.22e-0434315310GO:0005261
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR2 RYR3

3.46e-0441532GO:0005219
GeneOntologyMolecularFunctiondemethylase activity

CYP1A1 CYP1A2 KDM5B RIOX1

3.54e-04441534GO:0032451
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1C CACNA1F CACNA2D2 CACNA1H

4.21e-04461534GO:0005245
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

4.81e-041291536GO:0005262
GeneOntologyMolecularFunctionkeratin filament binding

VIM EPPK1

8.57e-0461532GO:1990254
GeneOntologyMolecularFunctionhistone H3K4me/H3K4me2/H3K4me3 demethylase activity

KDM5B RIOX1

8.57e-0461532GO:0034647
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR2 RYR3

8.57e-0461532GO:0048763
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

1.10e-031511536GO:0015085
GeneOntologyMolecularFunctionhydroperoxy icosatetraenoate dehydratase activity

CYP1A1 CYP1A2

1.19e-0371532GO:0106256
GeneOntologyMolecularFunction2-oxoglutarate-dependent dioxygenase activity

KDM5B JMJD4 RIOX1 ALKBH6

1.56e-03651534GO:0016706
GeneOntologyMolecularFunctionhistone H3K4 demethylase activity

KDM5B RIOX1

1.58e-0381532GO:0032453
GeneOntologyMolecularFunctionestrogen 2-hydroxylase activity

CYP1A1 CYP1A2

1.58e-0381532GO:0101021
GeneOntologyMolecularFunctioncalmodulin binding

MYO1G CACNA1C OBSCN RYR2 RYR3 SCN2A SCN3A

2.01e-032301537GO:0005516
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNA1C SCN1A SCN2A SCN3A CACNA1H

6.80e-06361545GO:0086010
GeneOntologyCellularComponentmitochondrial nucleoid

SHMT2 TWNK CPS1 ATAD3C ATAD3A DDX28

2.06e-06511556GO:0042645
GeneOntologyCellularComponentnucleoid

SHMT2 TWNK CPS1 ATAD3C ATAD3A DDX28

2.06e-06511556GO:0009295
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN3A CACNA1H

6.42e-06171554GO:0001518
GeneOntologyCellularComponentcalcium channel complex

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

1.70e-05731556GO:0034704
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN3A CACNA1H

5.98e-05291554GO:0034706
GeneOntologyCellularComponentcation channel complex

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 SCN1A SCN2A SCN3A CACNA1H

6.67e-052351559GO:0034703
GeneOntologyCellularComponentsarcolemma

CACNA1C OBSCN POPDC2 RYR2 RYR3 SCN1A SCN2A CACNA1H

8.86e-051901558GO:0042383
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 NALCN SCN1A SCN2A SCN3A CACNA1H GABRR3

1.24e-0437815511GO:0034702
GeneOntologyCellularComponentAP-5 adaptor complex

AP5S1 AP5Z1

3.25e-0441552GO:0044599
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1C CACNA1F CACNA2D2 CACNA1H

3.72e-04461554GO:0005891
GeneOntologyCellularComponentAP-type membrane coat adaptor complex

AP5S1 AP3B1 AP5Z1 AP3B2

4.39e-04481554GO:0030119
GeneOntologyCellularComponentZ disc

CACNA1C OBSCN RYR2 RYR3 SCN1A ASB2

9.29e-041511556GO:0030018
GeneOntologyCellularComponentI band

CACNA1C OBSCN RYR2 RYR3 SCN1A ASB2

1.51e-031661556GO:0031674
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 NALCN SCN1A SCN2A SCN3A CACNA1H GABRR3

1.84e-0352315511GO:1902495
DomainChannel_four-helix_dom

CACNA1C CACNA1F NALCN SCN1A SCN2A SCN3A CACNA1H

4.05e-07571537IPR027359
Domain-

CACNA1C CACNA1F NALCN SCN1A SCN2A SCN3A CACNA1H

4.05e-075715371.20.120.350
DomainIon_trans_dom

CACNA1C CACNA1F RYR2 RYR3 NALCN SCN1A SCN2A SCN3A CACNA1H

4.09e-071141539IPR005821
DomainIon_trans

CACNA1C CACNA1F RYR2 RYR3 NALCN SCN1A SCN2A SCN3A CACNA1H

4.09e-071141539PF00520
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A

1.06e-0561533PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN3A

1.06e-0561533IPR024583
DomainNa_channel_asu

SCN1A SCN2A SCN3A

6.20e-05101533IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN3A

6.20e-05101533IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN3A

6.20e-05101533PF06512
DomainVDCCAlpha1

CACNA1C CACNA1F CACNA1H

6.20e-05101533IPR002077
DomainAP3_beta

AP3B1 AP3B2

6.67e-0521532IPR026740
DomainCyt_P450_E_grp-I_CYP1

CYP1A1 CYP1A2

6.67e-0521532IPR008066
DomainAP3B_C

AP3B1 AP3B2

6.67e-0521532IPR029390
DomainAP3B1_C

AP3B1 AP3B2

6.67e-0521532PF14796
DomainTATA-bd_TIP120

CAND1 CAND2

6.67e-0521532IPR013932
DomainTIP120

CAND1 CAND2

6.67e-0521532PF08623
DomainAP3B1_C

AP3B1 AP3B2

6.67e-0521532SM01355
DomainCadherin_2

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16

1.92e-04651535PF08266
DomainCadherin_N

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16

1.92e-04651535IPR013164
DomainCAC1F_C

CACNA1C CACNA1F

1.99e-0431532IPR031688
DomainRyanodine_rcpt

RYR2 RYR3

1.99e-0431532IPR003032
DomainDUF3523

ATAD3C ATAD3A

1.99e-0431532IPR021911
DomainRyanrecept_TM4-6

RYR2 RYR3

1.99e-0431532IPR009460
DomainRyR

RYR2 RYR3

1.99e-0431532PF02026
DomainDUF3523

ATAD3C ATAD3A

1.99e-0431532PF12037
DomainCAC1F_C

CACNA1C CACNA1F

1.99e-0431532PF16885
DomainRR_TM4-6

RYR2 RYR3

1.99e-0431532PF06459
DomainRyan_recept

RYR2 RYR3

1.99e-0431532IPR013333
DomainCadherin_CS

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

2.77e-041091536IPR020894
DomainCADHERIN_1

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

3.37e-041131536PS00232
DomainCadherin

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

3.37e-041131536PF00028
DomainCADHERIN_2

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

3.53e-041141536PS50268
Domain-

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

3.53e-0411415362.60.40.60
DomainCA

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

3.70e-041151536SM00112
DomainCadherin_C

PCDHGA4 PCDHB10 PCDHB7 PCDHB16

3.80e-04421534IPR032455
DomainCadherin_C_2

PCDHGA4 PCDHB10 PCDHB7 PCDHB16

3.80e-04421534PF16492
DomainCadherin-like

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

3.87e-041161536IPR015919
DomainARM-like

CAND1 CAND2 TTI2 AP3B1 AP5Z1 ANKAR AP3B2 HTT PPP6R3

3.93e-042701539IPR011989
DomainVDCC_L_a1su

CACNA1C CACNA1F

3.96e-0441532IPR005446
DomainCadherin

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

4.25e-041181536IPR002126
DomainARM-type_fold

CAND1 CAND2 TTI2 AP3B1 RYR3 FOCAD ANKAR AP3B2 HTT PPP6R3

4.93e-0433915310IPR016024
DomainAP_beta

AP3B1 AP3B2

6.56e-0451532IPR026739
DomainRIH_assoc-dom

RYR2 RYR3

9.79e-0461532IPR013662
Domain-

EPPK1 MACF1

9.79e-04615323.90.1290.10
DomainFrag1

PGAP2 TMEM150C

9.79e-0461532PF10277
DomainFrag1/DRAM/Sfk1

PGAP2 TMEM150C

9.79e-0461532IPR019402
DomainIns145_P3_rec

RYR2 RYR3

9.79e-0461532PF08709
DomainRIH_assoc

RYR2 RYR3

9.79e-0461532PF08454
DomainRIH_dom

RYR2 RYR3

9.79e-0461532IPR000699
DomainIns145_P3_rcpt

RYR2 RYR3

9.79e-0461532IPR014821
DomainRyanodine_recept-rel

RYR2 RYR3

9.79e-0461532IPR015925
Domain-

RYR2 RYR3

9.79e-04615321.25.10.30
DomainRYDR_ITPR

RYR2 RYR3

9.79e-0461532PF01365
DomainPlectin

EPPK1 MACF1

1.36e-0371532PF00681
DomainCbamoylP_synth_lsu-like_ATP-bd

CPS1 PC

1.36e-0371532IPR005479
DomainBC-like_N

CPS1 PC

1.36e-0371532IPR005481
DomainCa_chan_IQ

CACNA1C CACNA1F

1.36e-0371532SM01062
DomainCa_chan_IQ

CACNA1C CACNA1F

1.36e-0371532PF08763
DomainPlectin_repeat

EPPK1 MACF1

1.36e-0371532IPR001101
DomainVDCC_a1su_IQ

CACNA1C CACNA1F

1.36e-0371532IPR014873
DomainCPSase_L_D2

CPS1 PC

1.36e-0371532PF02786
DomainGPHH

CACNA1C CACNA1F

1.36e-0371532PF16905
DomainGPHH_dom

CACNA1C CACNA1F

1.36e-0371532IPR031649
DomainBiotin_carb_N

CPS1 PC

1.36e-0371532PF00289
DomainPLEC

EPPK1 MACF1

1.36e-0371532SM00250
DomainLeu-rich_rpt

LRRC75B LRRC10B LRRC40 NLRP2 LINGO4 LRRC14 LGR6 FLRT1

1.79e-032711538IPR001611
DomainVPS9

RIN1 RINL

1.81e-0381532SM00167
DomainJMJC

KDM5B JMJD4 RIOX1

2.25e-03321533PS51184
DomainJmjC_dom

KDM5B JMJD4 RIOX1

2.25e-03321533IPR003347
Domain-

CAND1 CAND2 AP3B1 AP5Z1 ANKAR AP3B2 HTT

2.39e-0322215371.25.10.10
DomainJmjC

KDM5B JMJD4 RIOX1

2.46e-03331533SM00558
DomainEF-hand-dom_pair

CACNA1C CACNA1F CABP5 RYR2 RYR3 SCN1A SCN3A MACF1

2.56e-032871538IPR011992
DomainMIR

RYR2 RYR3

2.87e-03101532PF02815
DomainMIR_motif

RYR2 RYR3

2.87e-03101532IPR016093
DomainVPS9

RIN1 RINL

2.87e-03101532PS51205
DomainMIR

RYR2 RYR3

2.87e-03101532PS50919
DomainMIR

RYR2 RYR3

2.87e-03101532SM00472
DomainVPS9

RIN1 RINL

2.87e-03101532PF02204
DomainVPS9

RIN1 RINL

2.87e-03101532IPR003123
Domain-

TENM4 LRP1 LRP5

3.97e-033915332.120.10.30
DomainIQ

OBSCN SCN1A SCN2A SCN3A

4.42e-03811534SM00015
Domain-

DPYD HAO1 PC

4.90e-034215333.20.20.70
Domain-

CPS1 PC

4.90e-031315323.40.50.20
Domain-

LRRC75B LRRC10B LRRC40 NLRP2 LINGO4 LRRC14 LGR6 FLRT1

5.03e-0332115383.80.10.10
DomainAldolase_TIM

DPYD HAO1 PC

5.58e-03441533IPR013785
DomainATP_GRASP

CPS1 PC

5.69e-03141532PS50975
DomainATP-grasp

CPS1 PC

5.69e-03141532IPR011761
DomainPreATP-grasp_dom

CPS1 PC

5.69e-03141532IPR016185
DomainLdl_recept_b

LRP1 LRP5

5.69e-03141532PF00058
DomainLDLRB

LRP1 LRP5

5.69e-03141532PS51120
DomainSPRY

RYR2 RYR3 TRIM10 RFPL2

5.69e-03871534SM00449
DomainL_dom-like

LRRC75B LRRC10B LRRC40 NLRP2 LINGO4 LRRC14 LGR6 FLRT1

5.71e-033281538IPR032675
DomainLdl_recept_a

TMPRSS9 LRP1 LRP5

5.95e-03451533PF00057
Domain6-blade_b-propeller_TolB-like

TENM4 LRP1 LRP5

6.32e-03461533IPR011042
Domain-

TMPRSS9 LRP1 LRP5

6.32e-034615334.10.400.10
DomainIQ_motif_EF-hand-BS

OBSCN SCN1A SCN2A SCN3A

6.41e-03901534IPR000048
DomainClathrin/coatomer_adapt-like_N

AP3B1 AP3B2

6.53e-03151532IPR002553
DomainLY

LRP1 LRP5

6.53e-03151532SM00135
DomainAdaptin_N

AP3B1 AP3B2

6.53e-03151532PF01602
Domain-

CPS1 PC

6.53e-031515323.30.1490.20
PathwayREACTOME_MUSCLE_CONTRACTION

CACNA1C VIM CACNA2D2 RYR2 RYR3 GUCY1A2 SCN1A SCN2A SCN3A CACNA1H

3.80e-0620310910M5485
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

CACNA1C CACNA2D2 SCN1A SCN2A SCN3A

4.30e-06321095M27455
PathwayWP_ALZHEIMERS_DISEASE

CACNA1C CACNA1F RYR3 LRP1 TNFRSF1A EIF2AK3

2.25e-05741096MM15962
PathwayWP_RETT_SYNDROME

KDM5B STXBP1 SCN1A SCN2A HTT

3.31e-05481095M39759
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1C CACNA1F CACNA2D2 CACNA1H

3.77e-05251094M47948
PathwayWP_DRAVET_SYNDROME

STXBP1 SCN1A SCN2A SCN3A

6.00e-05281094M45519
PathwayREACTOME_CARDIAC_CONDUCTION

CACNA1C CACNA2D2 RYR2 RYR3 SCN1A SCN2A SCN3A

6.59e-051301097M27454
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1C RYR2 RYR3

7.09e-05111093M47958
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

CACNA1C CACNA1F CACNA2D2 ITGA10 RYR2

2.66e-04741095M16376
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

CACNA1C CACNA1F CACNA2D2 ITGA10 RYR2

2.66e-04741095M39462
PathwayWP_15Q25_COPY_NUMBER_VARIATION

RYR2 AP3B2 ALPK3 HTT

4.30e-04461094M48105
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

CACNA1C CACNA1F CACNA2D2 ITGA10 RYR2

4.53e-04831095M8728
PathwayKEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING

CACNA1C CACNA2D2 RYR2

5.40e-04211093M47950
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

SHROOM3 RTL6 EPPK1 BICRA ANKRD9 OBSCN TWNK GRID1 ICE1 FOCAD HEYL ARAP3 PNPLA6 CELSR3 TRIB3 BTBD7 CPSF1 LRP5 CACNA1H LRRC14 ZNF324B PC ALKBH6 HTT

2.28e-1011051582435748872
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A SCN3A

9.20e-083158323859570
Pubmed

Synaptic ribbons foster active zone stability and illumination-dependent active zone enrichment of RIM2 and Cav1.4 in photoreceptor synapses.

CACNA1F AP3B1 CTBP2

9.20e-083158332249787
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A SCN3A

9.20e-083158312610651
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A SCN3A

9.20e-083158318784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A SCN3A

9.20e-083158317544618
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A SCN3A

9.20e-083158314973256
Pubmed

The layered structure of human mitochondrial DNA nucleoids.

SHMT2 TWNK CPS1 ATAD3A DDX28

3.31e-0732158518063578
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN3A

3.67e-074158317537961
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A SCN3A

3.67e-074158335801810
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN3A

3.67e-074158335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN3A

3.67e-074158329578003
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A SCN3A

3.67e-07415838974318
Pubmed

Three brain sodium channel alpha-subunit genes are clustered on the proximal segment of mouse chromosome 2.

SCN1A SCN2A SCN3A

9.14e-07515831679748
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN3A

9.14e-07515838812438
Pubmed

Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy.

SCN1A SCN2A SCN3A

9.14e-075158324337656
Pubmed

A striking organization of a large family of human neural cadherin-like cell adhesion genes.

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

9.75e-0772158610380929
Pubmed

Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 CELSR3

1.82e-0680158610716726
Pubmed

HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization.

RYR2 RYR3 EIF2AK3

1.82e-066158319009018
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN3A

1.82e-066158323652591
Pubmed

ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.

CACNA1C RYR2 EIF2AK3

1.82e-066158316352659
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

STXBP1 SCN1A SCN2A

3.18e-067158325818041
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1C CACNA1F CACNA1H

3.18e-067158312900400
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1C CACNA1F CACNA2D2 RYR2 SCN1A SCN3A CACNA1H

3.61e-06139158716985003
Pubmed

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects.

ATAD3C ATAD3A HTT

5.07e-068158330914652
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

CACNA1C RYR2 RYR3

5.07e-068158311784029
Pubmed

CEMIP, acting as a scaffold protein for bridging GRAF1 and MIB1, promotes colorectal cancer metastasis via activating CDC42/MAPK pathway.

VIM SHROOM3 ATAD3A MIB1 PC

6.28e-0657158536849460
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

VIM OBSCN GRID1 CARD8 RIN1 STXBP1 LRP1 LRP5

6.58e-06214158822199357
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN3A

7.57e-069158316382098
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1C CACNA1F CACNA1H

7.57e-069158316382099
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN3A

7.57e-069158315746173
Pubmed

Genetic profile of patients with epilepsy on first-line antiepileptic drugs and potential directions for personalized treatment.

CYP1A2 SCN1A SCN2A

1.08e-0510158320602612
Pubmed

NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.

CACNA1C CACNA1F CACNA1H

1.48e-0511158318809727
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

CACNA1C RYR2 RYR3

1.96e-0512158319095005
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN3A

1.96e-0512158330175250
Pubmed

Quantitative trait loci mapping of genes that influence the sensitivity and tolerance to ethanol-induced hypothermia in BXD recombinant inbred mice.

SCN1A SCN2A SCN3A

1.96e-051215838169823
Pubmed

Array-CGH detection of a de novo 2.8 Mb deletion in 2q24.2-->q24.3 in a girl with autistic features and developmental delay.

SCN2A SCN3A

2.05e-052158220346423
Pubmed

Methylation differences in the murine P1450 and P3450 genes in wild-type and mutant hepatoma cell culture.

CYP1A1 CYP1A2

2.05e-05215822425809
Pubmed

PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress.

ATAD3A EIF2AK3

2.05e-052158239116259
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

2.05e-052158210827969
Pubmed

Cloning and isolation of human cytochrome P-450 cDNAs homologous to dioxin-inducible rabbit mRNAs encoding P-450 4 and P-450 6.

CYP1A1 CYP1A2

2.05e-05215823000715
Pubmed

"ATAD3C regulates ATAD3A assembly and function in the mitochondrial membrane".

ATAD3C ATAD3A

2.05e-052158238092275
Pubmed

Characterization of human CYP1A1/1A2 induction by DNA microarray and alpha-naphthoflavone.

CYP1A1 CYP1A2

2.05e-052158212147246
Pubmed

Riluzole metabolism and CYP1A1/2 polymorphisms in patients with ALS.

CYP1A1 CYP1A2

2.05e-052158217852022
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

2.05e-052158219694741
Pubmed

Genomic structures of SCN2A and SCN3A - candidate genes for deafness at the DFNA16 locus.

SCN2A SCN3A

2.05e-052158211245985
Pubmed

Cyp1a2 protects against reactive oxygen production in mouse liver microsomes.

CYP1A1 CYP1A2

2.05e-052158214980704
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

2.05e-05215821317301
Pubmed

Characterization of Ca2+-binding protein 5 knockout mouse retina.

CACNA1C CABP5

2.05e-052158218586882
Pubmed

Immunocytochemical study of cytochrome P450 (1A1/1A2) induction in murine ocular tissues.

CYP1A1 CYP1A2

2.05e-05215827781742
Pubmed

Organization of the CYP1A cluster on human chromosome 15: implications for gene regulation.

CYP1A1 CYP1A2

2.05e-052158211207026
Pubmed

Duplication of the sodium channel gene cluster on 2q24 in children with early onset epilepsy.

SCN2A SCN3A

2.05e-052158223016767
Pubmed

Tissue-specific expression of the mouse dioxin-inducible P(1)450 and P(3)450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues.

CYP1A1 CYP1A2

2.05e-05215823785172
Pubmed

Assignment of dioxin-inducible cytochrome P-450 gene family to Chinese hamster chromosome 4.

CYP1A1 CYP1A2

2.05e-05215823860967
Pubmed

Whole gene duplication of SCN2A and SCN3A is associated with neonatal seizures and a normal intellectual development.

SCN2A SCN3A

2.05e-052158227153334
Pubmed

Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype.

CYP1A1 CYP1A2

2.05e-052158216609368
Pubmed

Electrophysiological Differences between the Same Pore Region Mutation in SCN1A and SCN3A.

SCN1A SCN3A

2.05e-052158224990319
Pubmed

Cyp1a1(-/-) male mice: protection against high-dose TCDD-induced lethality and wasting syndrome, and resistance to intrahepatocyte lipid accumulation and uroporphyria.

CYP1A1 CYP1A2

2.05e-052158215094312
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

2.05e-052158231439038
Pubmed

Tissue-specific alternative splicing of mouse brain type ryanodine receptor/calcium release channel mRNA.

RYR2 RYR3

2.05e-05215828898078
Pubmed

CYP1A1 and CYP1A2 expression: comparing 'humanized' mouse lines and wild-type mice; comparing human and mouse hepatoma-derived cell lines.

CYP1A1 CYP1A2

2.05e-052158219285097
Pubmed

Genetic interactions found between calcium channel genes modulate amyloid load measured by positron emission tomography.

CACNA1C RYR3

2.05e-052158224026422
Pubmed

[Association of polymorph variants of CYP1A2 and CYP1A1 genes with reproductive and thyroid diseases in female workers of petrochemical industry].

CYP1A1 CYP1A2

2.05e-052158222855999
Pubmed

Differential regulation of expression of hepatic and pulmonary cytochrome P4501A enzymes by 3-methylcholanthrene in mice lacking the CYP1A2 gene.

CYP1A1 CYP1A2

2.05e-052158212438513
Pubmed

CACNA1H downregulation induces skeletal muscle atrophy involving endoplasmic reticulum stress activation and autophagy flux blockade.

CACNA1C CACNA1H

2.05e-052158232332705
Pubmed

The mouse sino-atrial node expresses both the type 2 and type 3 Ca(2+) release channels/ryanodine receptors.

RYR2 RYR3

2.05e-052158214550562
Pubmed

HNK-1 epitope-carrying tenascin-C spliced variant regulates the proliferation of mouse embryonic neural stem cells.

TNC B3GAT1

2.05e-052158220855890
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

2.05e-052158215249644
Pubmed

Mapping of a FEB3 homologous febrile seizure locus on mouse chromosome 2 containing candidate genes Scn1a and Scn3a.

SCN1A SCN3A

2.05e-052158227690330
Pubmed

Systematic screening identifies a 2-gene signature as a high-potential prognostic marker of undifferentiated pleomorphic sarcoma/myxofibrosarcoma.

ITGA10 PPP2R2B

2.05e-052158231742892
Pubmed

Induction of cytochromes P450 1A1 and 1A2 by tanshinones in human HepG2 hepatoma cell line.

CYP1A1 CYP1A2

2.05e-052158221262253
Pubmed

Epidermal Growth Factor Receptor Kinase Inhibitors Synergize with TCDD to Induce CYP1A1/1A2 in Human Breast Epithelial MCF10A Cells.

CYP1A1 CYP1A2

2.05e-052158226953171
Pubmed

Pharmacologic profiling of human and rat cytochrome P450 1A1 and 1A2 induction and competition.

CYP1A1 CYP1A2

2.05e-052158218493746
Pubmed

Polycyclic Aromatic Hydrocarbon-induced Pulmonary Carcinogenesis in Cytochrome P450 (CYP)1A1- and 1A2-Null Mice: Roles of CYP1A1 and CYP1A2.

CYP1A1 CYP1A2

2.05e-052158232726451
Pubmed

A shuffled CYP1A library shows both structural integrity and functional diversity.

CYP1A1 CYP1A2

2.05e-052158217823232
Pubmed

Correlations in timing of sodium channel expression, epilepsy, and sudden death in Dravet syndrome.

SCN1A SCN3A

2.05e-052158223965409
Pubmed

Comparison of the flanking regions and introns of the mouse 2,3,7,8-tetrachlorodibenzo-p-dioxin-inducible cytochrome P1-450 and P3-450 genes.

CYP1A1 CYP1A2

2.05e-05215823988744
Pubmed

CYP1A1 and CYP1A2 expression levels are differentially regulated in three-dimensional spheroids of liver cancer cells compared to two-dimensional monolayer cultures.

CYP1A1 CYP1A2

2.05e-052158226643992
Pubmed

Preferred binding orientations of phenacetin in CYP1A1 and CYP1A2 are associated with isoform-selective metabolism.

CYP1A1 CYP1A2

2.05e-052158222949628
Pubmed

Role of defective calcium regulation in cardiorespiratory dysfunction in Huntington's disease.

RYR2 HTT

2.05e-052158232897880
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

2.05e-052158230693367
Pubmed

Increased basal expression of hepatic Cyp1a1 and Cyp1a2 genes in inbred mice selected for susceptibility to acetaminophen-induced hepatotoxicity.

CYP1A1 CYP1A2

2.05e-05215829295056
Pubmed

Disruption of cytochrome P4501A2 in mice leads to increased susceptibility to hyperoxic lung injury.

CYP1A1 CYP1A2

2.05e-052158225680282
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

2.05e-052158229649454
Pubmed

Sex-specific differences in hyperoxic lung injury in mice: role of cytochrome P450 (CYP)1A.

CYP1A1 CYP1A2

2.05e-052158225703676
Pubmed

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease.

RYR2 RYR3

2.05e-052158221531043
Pubmed

Developmental and tissue-specific differential regulation of the mouse dioxin-inducible P1-450 and P3-450 genes.

CYP1A1 CYP1A2

2.05e-05215824054433
Pubmed

Modulation of calcium signalling by dominant negative splice variant of ryanodine receptor subtype 3 in native smooth muscle cells.

RYR2 RYR3

2.05e-052158216678258
Pubmed

Defining the Contribution of CYP1A1 and CYP1A2 to Drug Metabolism Using Humanized CYP1A1/1A2 and Cyp1a1/Cyp1a2 Knockout Mice.

CYP1A1 CYP1A2

2.05e-052158231147315
Pubmed

Aryl hydrocarbon (Ah) receptor-independent induction of Cyp1a2 gene expression by acenaphthylene and related compounds in B6C3F1 mice.

CYP1A1 CYP1A2

2.05e-05215828001243
Pubmed

Metabolism of 4-n-nonylphenol by non-modified and CYP1A1- and CYP1A2-transgenic cell cultures of tobacco.

CYP1A1 CYP1A2

2.05e-052158216402549
Pubmed

The effect of CYP1A1 and CYP1A2 polymorphisms on gastric cancer risk among different ethnicities: a systematic review and meta-analysis.

CYP1A1 CYP1A2

2.05e-052158224443269
Pubmed

Preferential inducibility of CYP1A1 and CYP1A2 by TCDD: differential regulation in primary human hepatocytes versus transformed human cells.

CYP1A1 CYP1A2

2.05e-052158216426572
Pubmed

Chronic hypoxia selectively enhances L- and T-type voltage-dependent Ca2+ channel activity in pulmonary artery by upregulating Cav1.2 and Cav3.2.

CACNA1C CACNA1H

2.05e-052158223686856
Pubmed

The influence of CYP1A1 and CYP1A2 polymorphisms on stroke risk in the Chinese population.

CYP1A1 CYP1A2

2.05e-052158233046100
Pubmed

Ca2+ influx through T- and L-type Ca2+ channels have different effects on myocyte contractility and induce unique cardiac phenotypes.

CACNA1C CACNA1H

2.05e-052158218832749
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

2.05e-052158233096315
Pubmed

CYP1A1/2 haplotypes and lung cancer and assessment of confounding by population stratification.

CYP1A1 CYP1A2

2.05e-052158219276377
Pubmed

Distinct genetic patterns of shared and unique genes across four neurodevelopmental disorders.

STXBP1 SCN2A

2.05e-052158232929885
Pubmed

Skeletal and cardiac ryanodine receptors bind to the Ca(2+)-sensor region of dihydropyridine receptor alpha(1C) subunit.

CACNA1C RYR2

2.05e-052158211576544
Cytoband5q31

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16

5.13e-0511515855q31
CytobandEnsembl 112 genes in cytogenetic band chr19q13

CABP5 BICRA FPR3 KLK12 SIGLEC5 BCL3 NLRP2 CARD8 GIPR FCGBP ZNF324 ZNF324B RINL ALKBH6

7.04e-05119215814chr19q13
CytobandEnsembl 112 genes in cytogenetic band chr5q31

PCDHGA4 PCDHB10 PCDHB7 PCDH12 PCDHB16 ARAP3

6.12e-042981586chr5q31
GeneFamilyCalcium voltage-gated channel subunits

CACNA1C CACNA1F CACNA2D2 CACNA1H

1.75e-05261104253
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN3A

1.79e-05911031203
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR2 RYR3

1.10e-0431102287
GeneFamilyCytochrome P450 family 1

CYP1A1 CYP1A2

2.18e-04411021000
GeneFamilyClustered protocadherins

PCDHGA4 PCDHB10 PCDHB7 PCDHB16

6.22e-0464110420
GeneFamilyAnkyrin repeat domain containing

ANKRD9 BCL3 ASB12 ARAP3 ANKAR MIB1 ASB2

6.98e-042421107403
GeneFamilyEF-hand domain containing|Plakins

EPPK1 MACF1

1.00e-0381102939
GeneFamilyVPS9 domain containing

RIN1 RINL

1.60e-03101102928
GeneFamilyLow density lipoprotein receptors

LRP1 LRP5

2.74e-03131102634
GeneFamilyFibronectin type III domain containing

COL7A1 TNC OBSCN IGSF9 FLRT1

2.96e-031601105555
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

CACNA1C EPPK1 TNC HEYL GUCY1A2 SCN3A CACNA1H LGR6

1.15e-07161158847b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

CACNA1C EPPK1 LRRC10B GRID1 HEYL SCN3A CACNA1H LGR6

2.60e-071791588a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F OBSCN GRID1 CPS1 RYR2 RYR3 TENM4 SCN2A

3.20e-0718415882cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F OBSCN GRID1 CPS1 RYR2 RYR3 TENM4 SCN2A

3.20e-071841588ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F OBSCN GRID1 CPS1 RYR2 RYR3 TENM4 SCN2A

3.20e-0718415882b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C POPDC2 RYR2 HEYL GUCY1A2 CACNA1H LGR6 ASB2

4.09e-07190158873d94fbae92029745989a8712eed8b99fd84c193
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-smooth_muscle_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C LRRC10B RYR2 HEYL GUCY1A2 SCN3A CACNA1H ASB2

4.26e-0719115888e8beb8e8a3b33cac83d3f7ce915a71e3654fdab
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C TNC GRID1 RYR2 TENM4 NALCN LRP1 LGR6

4.26e-07191158814057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D2 OBSCN POPDC2 RYR2 ALPK3 CACNA1H ASB2 INPP5J

4.26e-071911588c172c9e17b893b290e4aa8af5e5e4cd3e4818372
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D2 OBSCN POPDC2 RYR2 ALPK3 CACNA1H ASB2 INPP5J

4.26e-071911588715f5b449b8e075959c05a5b38389df319663164
ToppCelldroplet-Heart-nan-18m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN FAM174B POPDC2 RYR2 ALPK3 CACNA1H LGR6 ASB2

4.43e-0719215880bf99e029a06151092db1e8a0dcb45f4e688e771
ToppCelldroplet-Heart-nan-18m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN FAM174B POPDC2 RYR2 ALPK3 CACNA1H LGR6 ASB2

4.43e-071921588d766221acfce30cbf2c60b3ae40f6744968b952c
ToppCellnucseq-Mesenchymal-Myocytic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C COL7A1 OBSCN RYR2 HEYL TENM4 GUCY1A2 CACNA1H

4.79e-0719415882d66091097e106c7bee22e5281f50724700bdf8d
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C VIM GRID1 RYR2 HEYL SCN3A ALPK3 CACNA1H

5.59e-0719815887dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNA1C EPPK1 TNC GUCY1A2 SCN3A CACNA1H LGR6

1.71e-06160158729c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C HEYL GUCY1A2 B3GAT1 CACNA1H LGR6 ASB2

1.94e-06163158751dee6c21cbeca4e17d1cc386e203f0c403089e8
ToppCellControl-Fibroblasts-Pericytes|Control / group, cell type (main and fine annotations)

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

2.67e-061711587080003f698f867935c2bfc55d241d3650f45a0ab
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC10B GRID1 RYR2 HEYL SCN3A CACNA1H LGR6

3.11e-061751587316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC10B GRID1 RYR2 HEYL SCN3A CACNA1H LGR6

3.11e-061751587a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

3.48e-061781587185b44700f06ec58b3c09c80520502166c965fd6
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-enteroendocrine_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VIM LRRC10B GRID1 CELSR3 SCN3A AP3B2 CACNA1H

3.48e-06178158730ca37f70d267cc9b40ca3e211f16d30360c3e6b
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

CACNA1C COL7A1 OBSCN RYR2 HEYL GUCY1A2 CACNA1H

4.17e-061831587fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCellCOVID-19-Heart-CM_1|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C OBSCN POPDC2 RYR2 NALCN ALPK3 ASB2

4.32e-061841587e737f0f14c49b07bbb04a165083ac32210bc5690
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C POPDC2 RYR2 HEYL GUCY1A2 LGR6 ASB2

4.64e-061861587a95744b8649096bd7cfc3591a02841fa411085b3
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

4.81e-06187158786250acf088ec0c4800a0dfa031b0d4f7e52c342
ToppCellAdult-Mesenchymal-pericyte_cell|Adult / Lineage, Cell type, age group and donor

CACNA1C COL7A1 OBSCN RYR2 HEYL GUCY1A2 CACNA1H

4.81e-06187158762759efb660179402fb574ce5701c89a2e17bcfe
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

4.81e-061871587a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CACNA1C SHROOM3 TNC RYR2 RYR3 SCN3A MACF1

4.98e-06188158734e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

4.98e-061881587ee151792c7ac9afe820f1a281c6dab383799f358
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l39|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRRC10B RYR2 HEYL GUCY1A2 ZNF324 CACNA1H ASB2

4.98e-061881587a5e7a363fbd5ae4d9312cf6f9941413d6a5c0b4d
ToppCellMesenchymal-pericyte_cell|World / Lineage, Cell type, age group and donor

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

5.16e-061891587d7ed96add29f219183c802895fbff519b627f635
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C TNC RYR2 TENM4 NALCN LRP1 LGR6

5.16e-06189158745e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

5.34e-0619015874eb92aef1ee868f4537483d19014d947b7684612
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

5.34e-0619015877be4341e2909101d756f14031c21e705eb45e69a
ToppCelldroplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN POPDC2 RYR2 RYR3 ALPK3 ASB2 INPP5J

5.53e-06191158797fb4232417a39801e87725755fd16a57c250209
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C LRRC10B RYR2 GUCY1A2 SCN3A CACNA1H ASB2

5.53e-06191158760bc1f3efa7bbad5cb7944fe5e049ea79cd1745a
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C TNC RYR2 TENM4 NALCN LGR6 ASB2

5.53e-061911587b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCelldroplet-Heart-nan-3m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OBSCN POPDC2 RYR2 RYR3 ALPK3 ASB2 INPP5J

5.53e-06191158764070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCelldroplet-Heart-nan-24m-Mesenchymal-cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C CACNA2D2 OBSCN POPDC2 RYR2 ALPK3 ASB2

5.72e-061921587f6a4e348406a852ace9fb21db8fbdff539217645
ToppCelldroplet-Heart-nan-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C CACNA2D2 OBSCN POPDC2 RYR2 ALPK3 ASB2

5.72e-0619215871a0c25106ae08eac912a4edd5fc1a3ee776f69c2
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

CES1P1 CACNA1C COL7A1 TNC RYR2 NALCN MACF1

5.92e-0619315875896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

CACNA1C GRID1 RYR2 HEYL GUCY1A2 CACNA1H ASB2

6.12e-0619415875e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellproximal-Epithelial-Serous-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAM174B FKBP11 FCGBP NOXO1 BPIFB4 MAST1 GJC3

6.33e-06195158706b73abc1f32543f2a51db52dc6424a2a398fe0f
ToppCellproximal-Epithelial-Serous|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAM174B FKBP11 FCGBP NOXO1 BPIFB4 MAST1 GJC3

6.33e-061951587cb62f04f0e45bfb36eed2e7a3fc54d6d390b2ed1
ToppCellproximal-3-Epithelial-Serous|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAM174B FKBP11 FCGBP NOXO1 BPIFB4 MAST1 GJC3

6.33e-06195158724a6a566143b04e37ad002e4c55037a0460ac2ef
ToppCellsevere-Lymphocytic-CD8_T_cells|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

RTL6 CACNA2D2 PPP2R2B MACF1 B3GAT1 LGR6 PDZD4

6.55e-061961587d83acd9abd7b296989b8ae09da63799e6877a149
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C GRID1 RYR2 HEYL GUCY1A2 CACNA1H LGR6

6.55e-061961587754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-Myoepithelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C GASK1B RYR3 PPP2R2B NALCN LGR6 ASB2

6.77e-061971587f0475ad9c09c6da418dba17d3d3c1aaa2ef9ab4e
ToppCellParenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

6.77e-061971587f66945f9007d59d4208849c7fd727f8519713fbc
ToppCellParenchymal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

6.77e-06197158741dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C RYR2 PPP2R2B ALPK3 CACNA1H LGR6 ASB2

6.77e-061971587ac4f53acb2f8a428b0f2fab3c30a34e095a1bed7
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C TNC RYR2 HEYL GUCY1A2 CACNA1H ASB2

6.99e-061981587bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C RYR2 FOCAD STXBP1 SCN1A SCN2A SCN3A

6.99e-061981587c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C RYR2 FOCAD STXBP1 SCN1A SCN2A SCN3A

6.99e-0619815876d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C RYR2 FOCAD TENM4 STXBP1 SCN1A SCN2A

6.99e-0619815878ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C RYR2 FOCAD STXBP1 SCN1A SCN2A SCN3A

6.99e-0619815874ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C RYR2 PPP2R2B ALPK3 CACNA1H LGR6 ASB2

6.99e-061981587c12e7511628db819a52959bb68580e27c00c2e41
ToppCellBronchus_Control_(B.)-Stromal-TX-Smooth_muscle-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CACNA2D2 GRID1 POPDC2 RYR2 HEYL SCN3A CACNA1H

6.99e-0619815870f1feed8a37293ae02465909f99548ab58dc7ce5
ToppCellBronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

7.23e-061991587929f809579368201331d9099d8904b6e3c41797b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZDHHC21 COL7A1 SHROOM3 CACNA2D2 SCN2A MACF1 INPP5J

7.23e-0619915873cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCellBronchial-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

7.23e-061991587854628ce91068093c14bd4d45ba38c41469f3549
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW26|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.

TNC OBSCN ITGA10 RYR2 SCN2A LGR6 PDZD4

7.47e-06200158761d7dd0a78942b069c3f5e75044368dc00e6e8e6
ToppCellBronchial-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

7.47e-06200158712326cc6f0af24bacba9493dc79e7c7347db2f41
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GALNT15 CACNA1C VIM TNC ITGA10 TIPARP LRP1

7.47e-062001587a4ec0e80f5422b91b85264a9bb74568dd577e285
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C TNC RYR2 HEYL GUCY1A2 CACNA1H ASB2

7.47e-062001587a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellBronchial-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2 CACNA1H

7.47e-062001587362706445edb33b313684efe50b1f44f5f816e67
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.

TNC OBSCN ITGA10 RYR2 SCN2A MAST1 PDZD4

7.47e-0620015875c7263c862093ad9dbc81d06b16b6f74e8a6b634
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

CACNA2D2 PPP2R2B FCGBP MACF1 B3GAT1 LGR6 PDZD4

7.47e-062001587f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellBasal_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

COL7A1 EPPK1 TNC TMEM150C IGSF9 LGR6

2.66e-05164158685487a303194f5244956ec1ca2d1758d38117f41
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C LRRC10B RYR2 HEYL GUCY1A2 CACNA1H

2.75e-0516515868a82e20c9b1156bb4bbc16f7785abb04458d671b
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

COL7A1 EVC2 PCDHB10 PCDHB16 RYR2 GUCY1A2

2.85e-0516615867286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

COL7A1 EVC2 PCDHB10 PCDHB16 RYR2 GUCY1A2

2.85e-0516615867c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL7A1 TNC ITGA10 RIN1 PPP2R2B FLRT1

2.94e-051671586743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

SEMA4G SCN1A LINGO4 MAST1 INPP5J PDZD4

2.94e-0516715869efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL7A1 TNC ITGA10 RIN1 PPP2R2B FLRT1

2.94e-0516715861adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

SEMA4G SCN1A LINGO4 MAST1 INPP5J PDZD4

2.94e-051671586904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1C CAND2 ITGA10 RIN1 TENM4 LGR6

2.94e-051671586c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellAdult-Mesenchymal-pericyte_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1C OBSCN GRID1 RYR2 HEYL GUCY1A2

3.59e-051731586fd6653d6be9ca6ac36798590694efe03cb758c67
ToppCelldroplet-Heart-4Chambers-21m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA2D2 OBSCN FAM174B RYR2 CACNA1H ASB2

3.71e-051741586f098778ea74012861ec74b425e45776a31f67679
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 ITGA10 GUCY1A2 SCN3A FLRT1 ASB2

3.83e-051751586d8e385320f554d974538b7cdc4f8e4767f1455f2
ToppCellCOVID-19-Heart-VSMC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C GRID1 HEYL SCN3A CACNA1H LGR6

3.83e-0517515861125f0d3a5b2388fa77a820dea0288e824d84a82
ToppCellfacs-Heart-RV-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 ITGA10 GUCY1A2 SCN3A FLRT1 ASB2

3.83e-051751586cf15465855602ba135752c18755e3e058dbd42ec
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR3 NALCN SCN2A AP3B2 MAST1 B3GAT1

3.95e-051761586116741fef5895ca85057d2d31eca9eba5764ab44
ToppCelldroplet-Mammary_Gland-nan-21m-Endothelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 HAUS6 RTL6 POPDC2 RDH16 ASB2

3.95e-05176158627e5115fae5f0f63b333bc99fbf6a6d4c9182c46
ToppCell5'-GW_trimst-2-LargeIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELSR3 NALCN SCN2A AP3B2 MAST1 B3GAT1

3.95e-0517615865b707f58d164ee7a6a527dd5d053472ce9a631c1
ToppCelldroplet-Skin-nan-18m-Lymphocytic-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G VIM FAM174B ARAP3 CD163L1 RINL

4.21e-05178158612d5c6be6cfbf733e3cb02780606b3725eda7d2b
ToppCelldroplet-Skin-nan-18m-Lymphocytic-T_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G VIM FAM174B ARAP3 CD163L1 RINL

4.21e-051781586e0769ad06f92423a3cb6c78a61da3ba5bd9b4eae
ToppCelldroplet-Skin-nan-18m-Lymphocytic|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO1G VIM FAM174B ARAP3 CD163L1 RINL

4.21e-05178158611c2ce093b7538518c8d4497dc5b0b4da22bf1a8
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL7A1 SHROOM3 LRRC10B RYR2 HEYL GUCY1A2

4.34e-051791586f5bb4d3a27d56698473219970e764084096cc582
ToppCelldroplet-Lung-18m-Mesenchymal-myofibroblast-pericyte_cell-pericyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL7A1 SHROOM3 LRRC10B RYR2 HEYL GUCY1A2

4.34e-051791586fa03ec3cc0132f977b4cb28e7b23789732375183
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_2_(NPY+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNC HGSNAT OBSCN ITGA10 GRID1 GUCY1A2

4.34e-051791586a1ea8daa0fe8900f5a04b555c77fe8ebdaa3908d
ToppCelldroplet-Lung-nan-18m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 SHROOM3 LRRC10B RYR2 HEYL GUCY1A2

4.48e-051801586f6a05b3751b01e74b2de8440801b0eb2e723c199
ToppCelldroplet-Lung-nan-18m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL7A1 SHROOM3 LRRC10B RYR2 HEYL GUCY1A2

4.48e-051801586dfc75ae4395ff46fbec2c54915d98ead5a1ba1a1
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRRC75B CAND2 SHMT2 TIPARP HEYL GUCY1A2

4.62e-051811586274c0b768925cd5804483303f8c5ebd17a534c41
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C GRID1 RYR2 HEYL GUCY1A2 CACNA1H

4.62e-051811586451b87ac95154bb80018b8dd245b4a6389d81411
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

CACNA1C GRID1 HEYL GUCY1A2 SCN3A CACNA1H

4.62e-0518115868dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellCOVID-19-Heart-Fib_+_EC_+_Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C TNC GASK1B HEYL TENM4 GUCY1A2

4.76e-051821586fbd5e332df73bf7141c822fa67b76367dc962017
ToppCellAdult-Mesenchymal-airway_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

CACNA1C COL7A1 RYR3 TENM4 TRIB3 LGR6

4.76e-051821586ad4d74d8b19976e1ccc3c5ba8013199338cf6fd8
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TNC GRID1 RYR2 TENM4 NALCN LRP1

4.91e-0518315867eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellFetal_29-31_weeks-Mesenchymal-pericyte_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C GRID1 RYR2 HEYL GUCY1A2 CACNA1H

5.21e-051851586a7dba7db79275884b2a93d8a16f2e0c739e71370
DrugCNS 1145

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

8.93e-08331566CID000190902
DrugIHC-64

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

8.93e-08331566CID000162753
Drugnilvadipine

CACNA1C CYP1A2 CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

1.76e-07601567CID000004494
DrugDantrolene

CYP1A1 VIM CYP1A2 RYR2 RYR3 EIF2AK3

3.47e-07411566ctd:D003620
Drugisradipine

CACNA1C CYP1A2 CACNA1F CACNA2D2 RYR2 RYR3 SCN3A CACNA1H

4.43e-071001568CID000003784
DrugNSC7524

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 SCN2A SCN3A B3GAT1 CACNA1H EIF2AK3

5.32e-0718215610CID000005657
Drugnisoldipine

CACNA1C CYP1A2 CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

1.09e-06781567CID000004499
Druglamotrigine

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 SCN2A SCN3A CACNA1H

1.38e-061161568CID000003878
DrugCinildipine

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

2.30e-06561566CID000002752
Drugbepridil

CACNA1C CACNA1F CACNA2D2 TNC RYR2 RYR3 SCN3A CACNA1H

2.57e-061261568CID000002351
Drugphenytoin

CACNA1C CYP1A2 CACNA1F COL7A1 CACNA2D2 RYR2 RYR3 SCN2A SCN3A CACNA1H

2.85e-0621915610CID000001775
Drugriluzole

CACNA1C CYP1A2 CACNA1F CACNA2D2 GRID1 RYR2 RYR3 SCN3A CACNA1H

3.29e-061741569CID000005070
DrugIAA-94

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

3.82e-06611566CID000003667
Druglercanidipine

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

4.62e-06631566CID000065866
DrugZonisamide

SCN1A SCN2A SCN3A CACNA1H

4.71e-06171564DB00909
Drugfenpropathrin

CYP1A1 SCN2A SCN3A

6.22e-0661563ctd:C044267
Druggallopamil

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

6.64e-06671566CID000001234
DrugAC1L2AC7

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

7.89e-06691566CID000068733
DrugAcetazolamide [59-66-5]; Down 200; 18uM; PC3; HT_HG-U133A

JMJD4 BCL3 SEMA4G CARD8 RIN1 AP5Z1 AK2 LRRC14 PC

9.79e-0619915691808_DN
DrugIsradipine

CACNA1C CACNA2D2 CACNA1H

1.08e-0571563DB00270
DrugCAS 298-57-7

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

1.10e-05731566CID000002761
Drugethosuximide

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

1.19e-05741566CID000003291
DrugAC1NBU2S

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 GUCY1A2 CACNA1H

1.64e-051171567CID004473765
DrugNitrendipine

CACNA1C CACNA2D2 CACNA1H

1.72e-0581563DB01054
DrugN-cyclopentyl-N-cyclobutylformamide

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

1.73e-05791566CID005287890
Druggabapentin

CACNA1C CACNA1F CACNA2D2 GRID1 RYR2 RYR3 SCN3A CACNA1H

2.23e-051691568CID000003446
Drugfelodipine

CACNA1C CYP1A1 CYP1A2 CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

2.23e-051691568CID000003333
DrugCinnarizine

CACNA1C CACNA1F CACNA1H

2.57e-0591563DB00568
Drugpimozide

CACNA1C CYP1A2 CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

2.78e-051271567CID000016362
DrugPCB 95

CYP1A1 RYR2 RYR3

3.66e-05101563CID000038012
Drugcyclophorine

CACNA1C CYP1A2 CACNA1F COL7A1 EVC2 CACNA2D2 FPR3 KLK12 FKBP11 RYR2 RYR3 CACNA1H

3.92e-0542615612CID000002909
DrugAC1L1DXE

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 NOXO1 PNPLA6 B3GAT1 CACNA1H EIF2AK3

4.26e-0529915610CID000002548
Drug2-methoxy-4-aminoazobenzene

CYP1A1 CYP1A2

4.66e-0521562ctd:C053767
Drug3,4,3',4'-tetrachloroazoxybenzene

CYP1A1 CYP1A2

4.66e-0521562ctd:C013280
Drugcloflucarban

CYP1A1 CYP1A2

4.66e-0521562ctd:C005055
Drugmusk xylene

CYP1A1 CYP1A2

4.66e-0521562ctd:C031447
Drugsesamex

CYP1A1 CYP1A2

4.66e-0521562ctd:C100180
DrugCanthaxanthin

CYP1A1 CYP1A2

4.66e-0521562ctd:D016644
DrugPigment Yellow 74

CYP1A1 CYP1A2

4.66e-0521562CID000022829
Drugpyridoxal isonicotinoyl hydrazone

CYP1A1 CYP1A2

4.66e-0521562ctd:C021079
Drugnitroaniline

CYP1A1 CYP1A2

4.66e-0521562ctd:C008625
Drug7H-dibenzo(c,g)carbazole

CYP1A1 CYP1A2

4.66e-0521562ctd:C013478
Drug2,7-dinitrofluorene

CYP1A1 CYP1A2

4.66e-0521562ctd:C085049
Drugbeta-apo-8'-carotenal

CYP1A1 CYP1A2

4.66e-0521562ctd:C110652
Drugpropachlor

CYP1A1 CYP1A2

4.66e-0521562ctd:C011088
Drugallocryptopine

CYP1A1 CYP1A2

4.66e-0521562ctd:C109505
Drug2,7-FAA

CYP1A1 CYP1A2

4.66e-0521562CID000009352
Drugprotopine

CYP1A1 CYP1A2

4.66e-0521562ctd:C009093
Drugmanidipine

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

4.94e-05951566CID000004008
DrugMibefradil

CACNA1C CACNA1F CACNA1H

5.00e-05111563DB01388
DrugFelodipine

CACNA1C CACNA2D2 CACNA1H

5.00e-05111563DB01023
Drug0317956-0000 [391210-11-0]; Up 200; 1uM; MCF7; HT_HG-U133A

CYP1A1 IL17RC PCDH12 SEMA4G RNF6 CPSF1 LRRC14 ZNF324B

5.53e-0519215683858_UP
Drugisotetrandrine

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

5.55e-05971566CID000005422
Drugnitrendipine

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

5.88e-05981566CID000004507
DrugAG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A

NPHP1 COL7A1 TNC RYR3 SCN3A B3GAT1 CACNA1H LRRC14

6.39e-0519615686435_UP
Drugnicardipine

CACNA1C CYP1A2 CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

6.49e-051451567CID000004473
DrugDantrolene-13C3

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 AK2 CACNA1H

6.49e-051451567CID000002951
DrugMetampicillin sodium salt [6489-61-8]; Down 200; 10.4uM; PC3; HT_HG-U133A

CACNA2D2 ITGA10 IL17RC RYR2 AK2 DECR2 LRRC14 PC

6.87e-0519815682123_DN
DrugPentoxifylline [6493-05-6]; Up 200; 14.4uM; PC3; HT_HG-U133A

EPPK1 CACNA2D2 SEMA4G RYR2 RNF6 AP5Z1 LRP1 TMEM231

7.11e-0519915687319_UP
Drugmibefradil

CACNA1C CYP1A2 CACNA2D2 RYR3 CACNA1H

7.79e-05641565CID000060662
Drug1,8-dinitropyrene

CYP1A1 CYP1A2 TIPARP

8.58e-05131563ctd:C033310
Drugloperamide

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 CACNA1H

8.65e-051051566CID000003954
DrugVerapamil

CACNA1C CYP1A1 VIM CYP1A2 CACNA1F CACNA1H

8.65e-051051566ctd:D014700
DrugBM-1

XCR1 BCL3 HAO1 TNFRSF1A ALG1

9.04e-05661565CID000159986
Drugprocaine

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 SCN3A CACNA1H

9.10e-051531567CID000004914
Drugbutylparaben

CACNA1C CYP1A1 CYP1A2 CACNA1F CACNA2D2 STXBP1 CACNA1H

1.07e-041571567ctd:C038091
DrugFPL 64176

CACNA1C RYR2 RYR3

1.35e-04151563CID000003423
Drug2,3-diaminotoluene

CYP1A1 CYP1A2

1.39e-0431562ctd:C100420
Drug2-amino-1-methyl-6-phenyl-1H-imidazo(4,5-b)pyridine

CYP1A1 CYP1A2

1.39e-0431562ctd:C522525
Drug2-amino-1,7-dimethylimidazo(4,5-g)quinoxaline

CYP1A1 CYP1A2

1.39e-0431562ctd:C519626
Drugscutellarein

CYP1A1 CYP1A2

1.39e-0431562ctd:C458179
Druggenkwanin

CYP1A1 CYP1A2

1.39e-0431562ctd:C014568
Drugcis-diammineplatinum(II

RYR2 RYR3

1.39e-0431562CID000159790
Drug1-methoxyrutaecarpine

CYP1A1 CYP1A2

1.39e-0431562CID005319487
Drug2-hydroxyheptanoic acid

RYR2 RYR3

1.39e-0431562CID002750949
DrugSuppressor Factors, Immunologic

CYP1A1 CYP1A2

1.39e-0431562ctd:D013491
Drug8N3-cADPR

RYR2 RYR3

1.39e-0431562CID000127713
Drugalyssin

CYP1A1 CYP1A2

1.39e-0431562ctd:C524316
Drug2-oxohexyl isothiocyanate

CYP1A1 CYP1A2

1.39e-0431562ctd:C524315
Drugaminodantrolene

RYR2 RYR3

1.39e-0431562CID009570289
DrugTrichloroepoxypropane

CYP1A1 CYP1A2

1.39e-0431562ctd:D014239
Drug3-aminofluorene

CYP1A1 CYP1A2

1.39e-0431562CID000022818
Drug1-aminofluorene

CYP1A1 CYP1A2

1.39e-0431562CID000022817
Drug2,2',4,6'-tetramethoxystilbene

CYP1A1 CYP1A2

1.39e-0431562ctd:C541980
Drug6-nitrobenzo(a)pyrene

CYP1A1 CYP1A2

1.39e-0431562ctd:C034699
Drugchlortoluron

CYP1A1 CYP1A2

1.39e-0431562ctd:C007033
DrugAminoquinolines

CYP1A1 CYP1A2

1.39e-0431562ctd:D000634
Drug2-hydroxycarbazole

RYR2 RYR3

1.39e-0431562CID000093551
Drug2,3,6,7-tetrachlorobiphenylene

CYP1A1 PC

1.39e-0431562CID000081533
Drug7-(deoxyadenosin-N(6)--yl)aristolactam II

CYP1A1 CYP1A2

1.39e-0431562ctd:C405699
Drug1,2,3,7,8-pentachlorodibenzofuran

CYP1A1 CYP1A2

1.39e-0431562ctd:C057584
DrugRyanodyl 3-(pyridine-3-carboxylate

RYR2 RYR3

1.39e-0431562CID005748312
Drug7-nitrobenzanthracene

CYP1A1 CYP1A2

1.39e-0431562ctd:C038954
Drug1,2-dichloroethylene

CYP1A1 CYP1A2

1.39e-0431562ctd:C035384
DrugTCNB

VIM OBSCN RYR2 RYR3 MIB1 B3GAT1

1.72e-041191566CID000008330
Drug3,4',5-trimethoxystilbene

CYP1A1 VIM CYP1A2

2.00e-04171563ctd:C497286
DrugPD 150606

CYP1A1 SCN2A SCN3A

2.00e-04171563ctd:C100442
Drugpapaverine

CACNA1C CACNA1F CACNA2D2 RYR2 RYR3 GUCY1A2 CACNA1H

2.17e-041761567CID000004680
DrugIsradipine

CYP1A1 CYP1A2 CACNA1F

2.39e-04181563ctd:D017275
Drug15d-PGJ2; Down 200; 10uM; PC3; HT_HG-U133A

CYP1A1 TNC IL17RC BCL3 CPS1 LRRC14 PC

2.66e-0418215671231_DN
DiseaseLung Injury

CYP1A1 CYP1A2 TNC TNFRSF1A

3.50e-06211494C0273115
DiseaseChronic Lung Injury

CYP1A1 CYP1A2 TNC TNFRSF1A

3.50e-06211494C2350344
Diseasealcohol use disorder (implicated_via_orthology)

KDM5B SHMT2 RIOX1 RYR2 RYR3 GIPR STXBP1 CTBP2

7.08e-061951498DOID:1574 (implicated_via_orthology)
DiseaseHypertrophic Cardiomyopathy

CACNA1C OBSCN RYR2 ATAD3A ALPK3

1.04e-05571495C0007194
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN3A

1.48e-05101493DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN3A

1.48e-05101493DOID:0080422 (implicated_via_orthology)
Disease5-hydroxy-2-methylpyridine sulfate measurement

CYP1A1 CYP1A2

2.53e-0521492EFO_0801051
Diseaseserum clozapine measurement

CYP1A1 CYP1A2

2.53e-0521492EFO_0600041
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN3A

2.68e-05121493DOID:0060170 (implicated_via_orthology)
DiseaseInfantile Severe Myoclonic Epilepsy

STXBP1 SCN1A SCN2A

3.48e-05131493C0751122
Diseasepulmonary hypertension (biomarker_via_orthology)

CYP1A1 VIM TNC RYR2 RYR3

5.44e-05801495DOID:6432 (biomarker_via_orthology)
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

STXBP1 SCN1A SCN2A

6.73e-05161493C0393706
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR2 RYR3

7.57e-0531492DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR2 RYR3

7.57e-0531492DOID:8545 (implicated_via_orthology)
DiseaseHyperoxia

CYP1A1 TNFRSF1A

7.57e-0531492C0242706
Diseasealbuminuria

CYP1A1 CYP1A2 SHROOM3 CPS1 TMCO5B

1.17e-04941495EFO_0004285
DiseaseMotor Neuron Disease, Upper

VIM PNPLA6

1.51e-0441492C0521659
DiseaseMotor Neuron Disease, Secondary

VIM PNPLA6

1.51e-0441492C0543858
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1C CACNA1F

1.51e-0441492DOID:0060173 (implicated_via_orthology)
DiseaseMotor Neuron Disease

VIM PNPLA6

1.51e-0441492C0085084
DiseaseFamilial Motor Neuron Disease

VIM PNPLA6

1.51e-0441492C0270763
DiseaseMotor Neuron Disease, Lower

VIM PNPLA6

1.51e-0441492C0270764
DiseaseX-21286 measurement

CYP1A1 CYP1A2

1.51e-0441492EFO_0800804
DiseaseAnterior Horn Cell Disease

VIM PNPLA6

1.51e-0441492C0154681
Diseaseneuromuscular disease (implicated_via_orthology)

ATAD3C ATAD3A

1.51e-0441492DOID:440 (implicated_via_orthology)
Diseasesodium measurement

CYP1A1 CYP1A2 GIPR BTBD7 SCN2A

1.81e-041031495EFO_0009282
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN3A

1.81e-04221493DOID:2030 (implicated_via_orthology)
Diseaseepilepsy (implicated_via_orthology)

CACNA2D2 SCN1A SCN2A SCN3A MIB1 LRP1

1.86e-041631496DOID:1826 (implicated_via_orthology)
DiseaseEpilepsy

CACNA2D2 PCDH12 STXBP1 SCN1A SCN2A

2.35e-041091495C0014544
DiseaseLateral Sclerosis

VIM PNPLA6

2.51e-0451492C0154682
Diseaseresponse to trauma exposure, post-traumatic stress disorder symptom measurement

OR11L1 GRID1

2.51e-0451492EFO_0008483, EFO_0008535
Diseaseurinary potassium to creatinine ratio

CPS1 GIPR

3.75e-0461492EFO_0009882
DiseaseEpilepsy, Generalized

SCN1A CACNA1H

3.75e-0461492C0014548
Diseaseporphyria cutanea tarda (is_implicated_in)

CYP1A1 CYP1A2

3.75e-0461492DOID:3132 (is_implicated_in)
DiseaseManic Disorder

CACNA1C TENM4 SCN2A PC

4.67e-04711494C0024713
Diseaseserum urea measurement

CYP1A1 CYP1A2 SHROOM3 CPS1 GIPR LGR6

4.84e-041951496EFO_0009795
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

5.23e-0471492C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

5.23e-0471492C0751057
DiseaseAkinetic Petit Mal

CACNA2D2 CACNA1H

5.23e-0471492C0001890
DiseaseEpilepsy, Absence, Atypical

CACNA2D2 CACNA1H

5.23e-0471492C0751124
DiseaseAbsence Seizure Disorder

CACNA2D2 CACNA1H

5.23e-0471492C4553705
DiseaseJuvenile Absence Epilepsy

CACNA2D2 CACNA1H

5.23e-0471492C4317339
DiseaseChildhood Absence Epilepsy

CACNA2D2 CACNA1H

5.23e-0471492C4281785
DiseaseEpilepsy, Minor

CACNA2D2 CACNA1H

5.23e-0471492C4552765
DiseaseAbsence Epilepsy

CACNA2D2 CACNA1H

5.23e-0471492C0014553
Diseasenon-small cell lung carcinoma

CYP1A1 CYP1A2 CPS1 NALCN

5.75e-04751494EFO_0003060
DiseaseManic

CACNA1C TENM4 SCN2A PC

6.66e-04781494C0338831
DiseaseEarly Childhood Epilepsy, Myoclonic

STXBP1 SCN1A

6.95e-0481492C0393695
DiseaseIdiopathic Myoclonic Epilepsy

STXBP1 SCN1A

6.95e-0481492C0338478
DiseaseSymptomatic Myoclonic Epilepsy

STXBP1 SCN1A

6.95e-0481492C0338479
Diseasecerebellar ataxia (implicated_via_orthology)

PNPLA6 AARS2

6.95e-0481492DOID:0050753 (implicated_via_orthology)
DiseaseBenign Infantile Myoclonic Epilepsy

STXBP1 SCN1A

6.95e-0481492C0751120
Diseaseplasma clozapine measurement

CYP1A1 CYP1A2

6.95e-0481492EFO_0600038
DiseaseMyoclonic Encephalopathy

STXBP1 SCN1A

6.95e-0481492C0438414
DiseaseMyoclonic Absence Epilepsy

STXBP1 SCN1A

6.95e-0481492C0393703
DiseaseDepression, Bipolar

CACNA1C TENM4 SCN2A PC

6.99e-04791494C0005587
Diseasebipolar I disorder

MYO1G CACNA1C CACNA2D2 TENM4 PC

7.65e-041411495EFO_0009963
Diseaseadvanced glycation end-product measurement

CYP1A1 CYP1A2

8.91e-0491492EFO_0007819
DiseaseFebrile Convulsions

SCN1A SCN2A

8.91e-0491492C0009952
Diseaseresponse to 4'-epidoxorubicin, response to antineoplastic agent

ICE1 TNFRSF1A

8.91e-0491492GO_0097327, GO_1902522
DiseaseMyoclonic Epilepsy

STXBP1 SCN1A

8.91e-0491492C0014550
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A

8.91e-0491492C3502809
Diseaseparental longevity

GALNT15 SHROOM3 BICRA CPS1 RYR3 GUCY1A2 TCP11L2 AP5Z1 HTT

9.49e-044941499EFO_0007796
Diseasevery low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio

SHROOM3 BCL3 GIPR MACF1 MTMR9 HTT

9.52e-042221496EFO_0008317, EFO_0020943
Diseasetheophylline measurement

CYP1A1 CYP1A2

1.11e-03101492EFO_0021180
Diseasesweet beverage consumption measurement

CYP1A1 CYP1A2

1.11e-03101492EFO_0010090
Disease1,7-dimethylurate measurement

CYP1A1 CYP1A2

1.11e-03101492EFO_0021512
DiseasePleural Diseases

TNC CARD8

1.11e-03101492C0032226
DiseaseEpilepsy, Myoclonic, Infantile

STXBP1 SCN1A

1.11e-03101492C0917800
Disease1-methylxanthine measurement

CYP1A1 CYP1A2

1.35e-03111492EFO_0021174
Diseaseplasma N-desmethylclozapine measurement

CYP1A1 CYP1A2

1.35e-03111492EFO_0600039
DiseaseShortened QT interval

CACNA1C LRP5

1.35e-03111492C0151879
Disease5-acetylamino-6-amino-3-methyluracil measurement

CYP1A1 CYP1A2

1.35e-03111492EFO_0800951
DiseaseOccupational Diseases

CYP1A1 CARD8

1.35e-03111492C0028797
DiseaseMyoclonic Astatic Epilepsy

STXBP1 SCN1A

1.35e-03111492C0393702
DiseaseLong QT Syndrome

CYP1A1 RYR2

1.35e-03111492C0023976
Diseasecomparative body size at age 10, self-reported

GRID1 AP3B1 FOCAD GIPR STXBP1 BTBD7 CTBP2 PPP6R3

1.37e-034201498EFO_0009819
Diseaseleft ventricular systolic function measurement

OBSCN GIPR ALPK3

1.44e-03441493EFO_0008206
Diseaseparaxanthine measurement

CYP1A1 CYP1A2

1.62e-03121492EFO_0021178
Diseaseesophageal cancer (is_implicated_in)

CYP1A1 RNF6

1.90e-03131492DOID:5041 (is_implicated_in)
Diseaseximenoylcarnitine (C26:1) measurement

LRP5 PPP6R3

1.90e-03131492EFO_0800543
DiseaseBardet-Biedl Syndrome

NPHP1 BBS10

1.90e-03131492C0752166
DiseaseIntellectual Disability

TTI2 PCDH12 SCN1A PGAP2 SCN3A RLIM MACF1 HTT

2.03e-034471498C3714756
DiseaseBardet-Biedl syndrome (is_implicated_in)

NPHP1 BBS10

2.21e-03141492DOID:1935 (is_implicated_in)
Diseaseeating disorder, bipolar disorder

RYR2 NALCN

2.21e-03141492EFO_0005203, MONDO_0004985
Diseaseextrinsic allergic alveolitis (is_marker_for)

TNC TNFRSF1A

2.21e-03141492DOID:841 (is_marker_for)
Diseasegeneralised epilepsy

CACNA2D2 RYR2 SCN1A

2.33e-03521493EFO_0005917
DiseaseCiliopathies

NPHP1 EVC2 BBS10 TMEM231

2.38e-031101494C4277690
DiseaseMMR-related febrile seizures

SCN1A SCN2A

2.55e-03151492EFO_0006519
Disease1,3,7-trimethylurate measurement

CYP1A1 CYP1A2

2.55e-03151492EFO_0021172
DiseasePeripheral Nervous System Diseases

DPYD PNPLA6 CACNA1H

2.59e-03541493C4721453
Diseasecoffee consumption, cups of coffee per day measurement

CYP1A1 CYP1A2

2.90e-03161492EFO_0004330, EFO_0006782
DiseaseColorectal Neoplasms

CYP1A2 DPYD COL7A1 GRID1 GUCY1A2 LGR6

2.91e-032771496C0009404
DiseasePolydactyly

EVC2 BBS10 PNPLA6 TMEM231

2.98e-031171494C0152427
DiseaseColorectal Carcinoma

CYP1A2 DPYD COL7A1 EVC2 OBSCN GRID1 ARAP3 GUCY1A2 LRP1 LGR6

3.09e-0370214910C0009402
Diseasesyndrome (implicated_via_orthology)

ATAD3C ATAD3A

3.67e-03181492DOID:225 (implicated_via_orthology)
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

3.67e-03181492HP_0002373
DiseaseSjogren's syndrome (is_implicated_in)

CYP1A1 VIM

3.67e-03181492DOID:12894 (is_implicated_in)
Diseasevery low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

BCL3 CPS1 TENM4 MACF1 MTMR9 HTT

3.70e-032911496EFO_0008317, EFO_0020946
Diseasecaffeine metabolite measurement

CYP1A1 CYP1A2

4.09e-03191492EFO_0007872

Protein segments in the cluster

PeptideGeneStartEntry
RTPLTARLLRDTGLN

B3GAT1

126

Q9P2W7
GTRVSLTIRRVPRVL

ALKBH6

216

Q3KRA9
LTIRRVPRVLRAGLL

ALKBH6

221

Q3KRA9
EGRLRDPATITTLRV

PPP2R2B

136

Q00005
GSGLVTRLRERPALL

ALG1

266

Q9BT22
LFTGIRRESPRVGLL

ARAP3

1216

Q8WWN8
IRRAITGRIPESLRN

CTBP2

341

P56545
TAVELSLGRRTLRPA

CACNA2D2

826

Q9NY47
TELRPRGRSLVIIST

EIF2AK3

96

Q9NZJ5
RGRSLVIISTLDGRI

EIF2AK3

101

Q9NZJ5
GLRIVELTLPRVSVR

BPIFB4

226

P59827
LLPVTSRTRIRRSGV

ASB2

356

Q96Q27
RLGKPSLVRETSRIT

ATAD3A

326

Q9NVI7
ALVTRISILLRDLPT

FAM174B

76

Q3ZCQ3
AGLSPRTSRRILERV

ALPK3

1206

Q96L96
RPIALRAVTSIARAL

DPYD

771

Q12882
RLRLARSTLTLVPLL

GIPR

336

P48546
LRADRIEGILTRFLP

AP5S1

161

Q9NUS5
ALPLALRTVSRLVER

AP5Z1

786

O43299
LPLRVSTRRRGSLEE

CD163L1

1391

Q9NR16
SEEVSLIRRIIGLSP

BBS10

336

Q8TAM1
IRASALRVLSSIRVP

AP3B1

131

O00203
IRASALRVLSSIRVP

AP3B2

126

Q13367
LRQRLVLSTLSGRPV

RCL1

16

Q9Y2P8
ELDTVIGRSRRPRLS

CYP1A1

346

P04798
GSTPVLVLSRLDTIR

CYP1A2

81

P05177
GTLRSLRPILNTLLE

TIPARP

51

Q7Z3E1
LTARLFRPRLIIAGT

SHMT2

211

P34897
SGPRQILRSLVRLSV

PCDH12

926

Q9NPG4
APLVRLLRISTIAEG

ANKAR

1036

Q7Z5J8
AEVGLRLVRLRLDTP

CES1P1

266

Q9UKY3
RLVRLRLDTPTSLAL

CES1P1

271

Q9UKY3
PVRSGTARILIILVD

PCDHGA4

251

Q9Y5G9
RAFRVLRPLRLVSGV

CACNA1F

206

O60840
LTKLSLITAPRRERG

MISP

331

Q8IVT2
LPLDRDGTLVRLRFT

PGAP2

6

Q9UHJ9
GPTLLLNSDIIRARL

PNPLA6

811

Q8IY17
AEESRRSTPVGRLLL

GJC3

11

Q8NFK1
ERLVSLEPVISVRSR

C22orf46

201

C9J442
TRRQLGLVPREKSVT

NUP98

1111

P52948
LLRLRLPVRVTSSVQ

KLK12

111

Q9UKR0
LAQIILEPRSRTIRG

MTMR9

346

Q96QG7
LEPRSRTIRGFEALI

MTMR9

351

Q96QG7
EILTLTRAGIRLLPS

LGR6

331

Q9HBX8
RTVLVSSGLREPRAL

LRP1

3136

Q07954
ATPRSLLSQVRLVVR

ASB12

266

Q8WXK4
PDSLLIRRITGRLIH

AK2

131

P54819
ERLIRSLPTSLERAL

FPR3

311

P25089
LARRTDLRRISLDTP

LRP5

346

O75197
RLLGERLTPREISEV

CABP5

136

Q9NP86
LLSRIAGDRSRVVSP

GALNT15

296

Q8N3T1
SPRLAVRKRTIIALG

CAND1

186

Q86VP6
GTRLVVLPFRRESLA

CPSF1

156

Q10570
VIQVLRRSPRLRGDS

PDZD4

46

Q76G19
RRLTSLPIVAKGILR

HAO1

226

Q9UJM8
VIASRSLPRVLTAAR

DECR2

56

Q9NUI1
SLVTRLLLAPRRGLT

DDX28

11

Q9NUL7
IRASSPRVLLTVLAR

PDZD3

181

Q86UT5
GATLRRLLSVVLPTA

EVC2

1136

Q86UK5
VGLRRRLSQRTSLPT

LRRC75B

261

Q2VPJ9
LLKDIRSVLEPTRGR

METTL9

221

Q9H1A3
RSVLEPTRGRVILAL

METTL9

226

Q9H1A3
ALRTAPLRRATGIIL

HEYL

216

Q9NQ87
LELSGRRLRRLPSAV

LRRC10B

26

A6NIK2
LDTLIELVTRGRSIP

KDM5B

1036

Q9UGL1
ALLVTTRPRALRDLR

NLRP2

331

Q9NX02
PLISRRDAEVVLTSR

TWNK

251

Q96RR1
IVSSILRIPSTSGRR

OR11L1

221

Q8NGX0
RGSPALSREALVRVL

PCDHB10

536

Q9UN67
VAVRRLGRQESPLSL

MAST1

1326

Q9Y2H9
LISRLTESRGPLSVV

MACF1

1626

Q9UPN3
RITTPGSERVLLESR

MIB1

126

Q86YT6
TLSEPRSGLLVLVIR

OBSCN

6156

Q5VST9
RGSPALSREALVRVL

PCDHB16

536

Q9NRJ7
PRSGTALVRILVLDV

PCDHB7

221

Q9Y5E2
IIAAILRIPTSRGRH

OR6P1

221

Q8NGX9
RPVSSRSGARLLVLE

GASK1B

236

Q6UWH4
VIRRTAVDSGIPLLT

CPS1

1451

P31327
IDRRAVPARVSLGIT

GABRR3

291

A8MPY1
GRIIDTSLTRDPLVI

FKBP11

71

Q9NYL4
RTPAILISEVVRSLL

HTT

2691

P42858
TPDIIIASILRLIGR

ICE1

2161

Q9Y2F5
LRAFRVLRPLRLVSG

CACNA1C

236

Q13936
RSRLPVSLSEGRLRV

FCGBP

556

Q9Y6R7
LSSGVNLPARRVIIR

POLQ

446

O75417
GALRLLVPRLVLTVS

JMJD4

16

Q9H9V9
ILLRIASGTRLSIPI

CARD8

301

Q9Y2G2
VGILRRILRTLRDFP

ANKRD9

126

Q96BM1
ARLGKPSLVRETSRI

ATAD3C

101

Q5T2N8
EITDRTLRTPTRIIL

BTBD7

301

Q9P203
RLSPRRLRLSVGNVT

ITGA10

721

O75578
LRTSIGERKRSLSPL

HAUS6

896

Q7Z4H7
RDTLRRAILLLSPQG

GRID1

221

Q9ULK0
PRLRSVDTFRGIALI

HGSNAT

266

Q68CP4
ATRRVLERLVLALGP

COL7A1

1071

Q02388
PRGSTARTLLRLLLR

SDR42E2

381

A6NKP2
VRTIARDSLARIPLL

FLRT1

111

Q9NZU1
TIEPTSGIVRTVRRL

CELSR3

1011

Q9NYQ7
ASGRGLLPLVRTLVR

BCL3

316

P20749
RLLLLEESRRVSPSA

BICRA

1156

Q9NZM4
SAIRTVRVLRPLRAI

CACNA1H

196

O95180
EVSGPVLSELLRLLR

CAND2

731

O75155
AIRIRSILRSLIPLG

RYR2

2416

Q92736
TARTGLPRKTRIILE

MENT

51

Q9BUN1
ILRIIQLLGTTPRLR

FOCAD

526

Q5VW36
QLLGTTPRLRAVTLR

FOCAD

531

Q5VW36
TPRLRAVTLRLLTSL

FOCAD

536

Q5VW36
ALGRSPVVLSLERLV

IL17RC

11

Q8NAC3
EGTIRSRPSRISLIL

NPHP1

371

O15259
LEGNPLRTIRREIIS

LRRC40

341

Q9H9A6
LSPLVRLQELRLSGA

LINGO4

296

Q6UY18
TRDLVVRLPRLLTGS

MTERF3

276

Q96E29
LRISTRRPETLGELQ

NOXRED1

106

Q6NXP6
ILRTILKIPSAEGRR

OR10R2

241

Q8NGX6
ERVLLRLSTPFVIRT

GUCY1A2

376

P33402
LLRTRARIPGALQIT

RTL6

66

Q6ICC9
TPGRLPSIRSRDLTL

POLR3D

36

P05423
RPGRVVSLRERLLLT

RIN1

51

Q13671
VLPLVLSRGTLESLR

TMCO5B

276

A8MYB1
ITGGLPELASRLTRI

TCP11L2

356

Q8N4U5
LSLLPLVRRARGRVV

RDH16

146

O75452
PSIRLIFRRLSLGRI

OR5AU1

11

Q8NGC0
TLDLPALTRRLTAII

EPPK1

2561

P58107
TITLDLQVRRIRPGE

RNF6

396

Q9Y252
TPISNTGILELRRVR

SIGLEC5

291

O15389
TPGRISLRISESVLR

SHROOM3

1481

Q8TF72
ILATVLRAPTAAERR

OR6T1

221

Q8NGN1
SPTLFRVIRLARIGR

SCN3A

1616

Q9NY46
RRVGIPRVILSASIT

TMEM150C

161

B9EJG8
LGVPIVTDSTLRRRS

STXBP1

446

P61764
RLLATAERVARSPTI

NOXO1

106

Q8NFA2
RRIIDRTLRTLGPSD

AARS2

416

Q5JTZ9
SGSVLALPLRSRKIR

RIOX1

26

Q9H6W3
VSPQLTLRALRERLG

SPATA1

71

Q5VX52
SPTLFRVIRLARIGR

SCN1A

1631

P35498
ALARRVSLLRPLSRV

CHPF2

461

Q9P2E5
RSLGLLPALRLETVD

INPP5J

956

Q15735
LGVLSTLEPLTRLQR

RINL

31

Q6ZS11
STLRVPTLRCRVLVT

XCR1

136

P46094
GLSTSRPRVVIQLER

ZNF324

41

O75467
ELTNGLVALPSRLRR

SEMA4G

776

Q9NTN9
ELDGTILKSRPLRIR

PSPC1

136

Q8WXF1
LTDARIRRLLPSLIG

RSL1D1

156

O76021
PRSREVAREVLTSLL

TTI2

166

Q6NXR4
GEAIRIRSILRSLVP

RYR3

2311

Q15413
LRREPAERLTATGIL

TRIB3

296

Q96RU7
TIRIPIRRILNTGLS

RLIM

381

Q9NVW2
SPTLFRVIRLARIGR

SCN2A

1621

Q99250
ITLLAPERTRDITGL

TNC

1666

P24821
SAVRLRSSVPGVRLL

VIM

66

P08670
VALLELAGPVRRSRL

TMPRSS9

916

Q7Z410
RLLTQEARSLEGTPR

TENM4

501

Q6N022
ETPINRLSLLLSGRV

POPDC2

151

Q9HBU9
IRSLSLIRLEGVEGR

RFPL2

36

O75678
ISRLQPRVRILVDGS

IGSF9

271

Q9P2J2
PRVRILVDGSLRLLA

IGSF9

276

Q9P2J2
ATPGARLLLRITKRT

ZC3H11B

501

A0A1B0GTU1
LVALVRASITDPGRL

ZDHHC21

61

Q8IVQ6
LTGTVTLELRRAPRL

TMEM253

76

P0C7T8
RLQGDRLRVPLVSTR

TMEM231

91

Q9H6L2
PARELLTDIRSTLIR

TRIM10

246

Q9UDY6
ILILQLPSTRGGRRS

nan

106

Q6ZS52
ILLTLLETRRPTFEG

PPP6R3

271

Q5H9R7
TPRREATLELLGRVL

TNFRSF1A

411

P19438
LRLLGIRRTSTAPAA

PC

11

P11498
GLSTSRPRVVIQLER

ZNF324B

41

Q6AW86
AIAEIRRLRPGSIET

DUSP23

121

Q9BVJ7
LREALRSSVGSPLRL

LRRC14

181

Q15048
ELPRTRITNILKRSG

NALCN

161

Q8IZF0
ATPRDLVLRSLLART

MYO1G

316

B0I1T2
PRTLVTLEQSRARLI

MYO1G

696

B0I1T2