Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionSUMO ligase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.91e-09201466GO:0061665
GeneOntologyMolecularFunctionpeptidyl-prolyl cis-trans isomerase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 PTPA RGPD3

7.42e-08501467GO:0003755
GeneOntologyMolecularFunctioncis-trans isomerase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 PTPA RGPD3

1.12e-07531467GO:0016859
GeneOntologyMolecularFunctionGTPase activator activity

RGPD4 DOCK4 RGPD2 RANBP2 RGPD8 MYO9A STXBP5L RGPD1 IQGAP1 RGPD3 ARAP1 ARAP2 RGPD5

1.42e-0727914613GO:0005096
GeneOntologyMolecularFunctionSUMO transferase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.24e-07361466GO:0019789
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RGPD4 DOCK4 RGPD2 CCZ1B RANBP2 RGPD8 MYO9A STXBP5L RGPD1 DOCK10 IQGAP1 CCZ1 RGPD3 ARAP1 ARAP2 RGPD5

9.84e-0750714616GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RGPD4 DOCK4 RGPD2 CCZ1B RANBP2 RGPD8 MYO9A STXBP5L RGPD1 DOCK10 IQGAP1 CCZ1 RGPD3 ARAP1 ARAP2 RGPD5

9.84e-0750714616GO:0030695
GeneOntologyMolecularFunctionenzyme activator activity

RGPD4 DOCK4 RGPD2 RANBP2 ERCC6 RGPD8 MYO9A STXBP5L RGPD1 IQGAP1 PTPA GUCA1A RGPD3 ARAP1 ARAP2 RGPD5 VEGFA

6.34e-0665614617GO:0008047
GeneOntologyMolecularFunctionisomerase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RENBP PTPA RGPD3

8.59e-051921468GO:0016853
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

RGPD4 RGPD2 RANBP2 NEDD4L RGPD8 DTL RGPD1 UBE2D2 UBE2D3 UBE2D4 RGPD3 SMURF2 CDC23

1.01e-0451214613GO:0019787
GeneOntologyMolecularFunctionsmall GTPase binding

RGPD4 DOCK4 RGPD2 RANBP2 RGPD8 RGPD1 DOCK10 GRIA1 IQGAP1 RGPD3

1.29e-0432114610GO:0031267
GeneOntologyMolecularFunctionaminoacyltransferase activity

RGPD4 RGPD2 RANBP2 NEDD4L RGPD8 DTL RGPD1 UBE2D2 UBE2D3 UBE2D4 RGPD3 SMURF2 CDC23

1.48e-0453214613GO:0016755
GeneOntologyMolecularFunctionmolecular function activator activity

RGPD4 DOCK4 RGPD2 RANBP2 ERCC6 CRLF1 RGPD8 MYO9A STXBP5L RGPD1 IQGAP1 PTPA GUCA1A EBI3 EPHA2 RGPD3 FGF2 ARAP1 ARAP2 RGPD5 VEGFA

2.51e-04123314621GO:0140677
GeneOntologyMolecularFunctionGTPase binding

RGPD4 DOCK4 RGPD2 RANBP2 RGPD8 RGPD1 DOCK10 GRIA1 IQGAP1 RGPD3

3.24e-0436014610GO:0051020
GeneOntologyMolecularFunctionphosphatidylinositol-3,4,5-trisphosphate binding

MYO1B IQGAP1 ARAP1 ARAP2

4.50e-04491464GO:0005547
GeneOntologyMolecularFunctionDNA translocase activity

ATRX RAD54L

5.23e-0451462GO:0015616
GeneOntologyMolecularFunctionacyltransferase activity

RGPD4 RGPD2 RANBP2 NEDD4L RGPD8 DTL RGPD1 SIRT4 UBE2D2 UBE2D3 UBE2D4 RGPD3 CDYL SMURF2 CDC23

5.65e-0477514615GO:0016746
GeneOntologyMolecularFunctionenzyme regulator activity

RGPD4 DOCK4 RGPD2 CCZ1B RANBP2 ERCC6 RGPD8 MYO9A STXBP5L PPP1R3B RGPD1 DOCK10 RENBP IQGAP1 PTPA GUCA1A CCZ1 RGPD3 ARAP1 ARAP2 RGPD5 VEGFA

6.37e-04141814622GO:0030234
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

RGPD4 RGPD2 RANBP2 NEDD4L RGPD8 RGPD1 UBE2D2 UBE2D3 RGPD3 SMURF2

7.07e-0439814610GO:0061659
GeneOntologyMolecularFunctionamyloid-beta binding

LILRB2 GRIA1 CLU CD36 LRP1

9.20e-041021465GO:0001540
GeneOntologyMolecularFunctioncytoskeletal motor activity

MYO1A MYO9A DNAH2 MYO1B DYNC1H1

1.76e-031181465GO:0003774
GeneOntologyMolecularFunctionATP-dependent activity

ERCC6 MYO1A ATRX MYO9A DDX60 ACSS1 DNAH2 ABCB6 MYO1B CLU DYNC1H1 RAD54L

1.87e-0361414612GO:0140657
GeneOntologyBiologicalProcesspositive regulation of glucokinase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

8.61e-1291446GO:0033133
GeneOntologyBiologicalProcesspositive regulation of hexokinase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.14e-11101446GO:1903301
GeneOntologyBiologicalProcessNLS-bearing protein import into nucleus

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

5.01e-11201447GO:0006607
GeneOntologyBiologicalProcessregulation of glucokinase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.72e-10131446GO:0033131
GeneOntologyBiologicalProcessregulation of hexokinase activity

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.99e-10141446GO:1903299
GeneOntologyBiologicalProcessprotein peptidyl-prolyl isomerization

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.40e-07381446GO:0000413
GeneOntologyBiologicalProcesspeptidyl-proline modification

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.04e-06541446GO:0018208
GeneOntologyBiologicalProcesspositive regulation of phosphorus metabolic process

RGPD4 RGPD2 HNF1A RANBP2 ERCC6 CRLF1 RGPD8 LILRB2 RGPD1 IQGAP1 FNDC1 PTPA GUCA1A PTPRZ1 EPHA2 CD36 RGPD3 FGF2 CTNND1 VEGFA

3.22e-0687914420GO:0010562
GeneOntologyBiologicalProcesspositive regulation of phosphate metabolic process

RGPD4 RGPD2 HNF1A RANBP2 ERCC6 CRLF1 RGPD8 LILRB2 RGPD1 IQGAP1 FNDC1 PTPA GUCA1A PTPRZ1 EPHA2 CD36 RGPD3 FGF2 CTNND1 VEGFA

3.22e-0687914420GO:0045937
GeneOntologyBiologicalProcessprotein K11-linked ubiquitination

UBE2D2 UBE2D3 UBE2D4 ANAPC5 CDC23

5.63e-06371445GO:0070979
GeneOntologyBiologicalProcessprotein import into nucleus

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 CRY2 CD36 RGPD3 RGPD5

9.51e-061951449GO:0006606
GeneOntologyBiologicalProcessregulation of gluconeogenesis

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.03e-05711446GO:0006111
GeneOntologyBiologicalProcessimport into nucleus

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 CRY2 CD36 RGPD3 RGPD5

1.21e-052011449GO:0051170
GeneOntologyBiologicalProcessgluconeogenesis

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 GOT1

1.29e-051111447GO:0006094
GeneOntologyBiologicalProcessestablishment of protein localization to organelle

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 SRP19 SIRT4 CRY2 UBE2D3 CLU CD36 RGPD3 VPS53 RGPD5

1.55e-0551514414GO:0072594
GeneOntologyBiologicalProcesshexose biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 GOT1

1.63e-051151447GO:0019319
GeneOntologyBiologicalProcessmonosaccharide biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 GOT1

2.27e-051211447GO:0046364
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

RGPD4 RGPD2 HNF1A RANBP2 ERCC6 CRLF1 RGPD8 RGPD1 IQGAP1 FNDC1 PTPRZ1 EPHA2 CD36 RGPD3 FGF2 CTNND1 VEGFA

3.23e-0578014417GO:0042327
GeneOntologyBiologicalProcessregulation of carbohydrate biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD8 PPP1R3B RGPD1 RGPD3

3.98e-051321447GO:0043255
GeneOntologyBiologicalProcessprotein localization to organelle

RGPD4 RGPD2 SEC16B RANBP2 RGPD8 ATRX RGPD1 BBS2 SRP19 SIRT4 CRY2 UBE2D3 BRD2 CLU CD36 RGPD3 IFT80 VPS53 RGPD5 VEGFA

7.24e-05109114420GO:0033365
GeneOntologyBiologicalProcessprotein K48-linked ubiquitination

NEDD4L UBE2D2 UBE2D3 UBE2D4 ANAPC5 CDC23

7.25e-051001446GO:0070936
GeneOntologyBiologicalProcessprotein K29-linked ubiquitination

UBE2D2 UBE2D3 UBE2D4

9.05e-05131443GO:0035519
GeneOntologyBiologicalProcessprotein K27-linked ubiquitination

UBE2D2 UBE2D3 UBE2D4

1.15e-04141443GO:0044314
GeneOntologyBiologicalProcesscardiac muscle thin filament assembly

NRAP NEB

1.45e-0431442GO:0071691
GeneOntologyBiologicalProcessamyloid-beta clearance

TTPA CLU CD36 LRP1

1.71e-04401444GO:0097242
GeneOntologyBiologicalProcessprotein K6-linked ubiquitination

UBE2D2 UBE2D3 UBE2D4

2.11e-04171443GO:0085020
GeneOntologyBiologicalProcesspositive regulation of peptidyl-tyrosine autophosphorylation

IQGAP1 CTNND1

2.88e-0441442GO:1900086
GeneOntologyBiologicalProcessregulation of amyloid-beta clearance

TTPA CLU LRP1

3.48e-04201443GO:1900221
GeneOntologyBiologicalProcesscarbohydrate biosynthetic process

RGPD4 RGPD2 RANBP2 RGPD8 PPP1R3B RGPD1 RGPD3 GOT1

3.51e-042471448GO:0016051
GeneOntologyBiologicalProcessregulation of glucose metabolic process

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.60e-041341446GO:0010906
GeneOntologyBiologicalProcesspeptidyl-amino acid modification

RGPD4 RGPD2 HNF1A RANBP2 AKT3 ERCC6 CRLF1 RGPD8 RGPD1 SIRT4 IQGAP1 PTPRZ1 CD36 RGPD3 CTNND1 AGBL2 VEGFA

4.72e-0497614417GO:0018193
GeneOntologyBiologicalProcessregulation of peptidyl-tyrosine autophosphorylation

IQGAP1 CTNND1

4.77e-0451442GO:1900084
GeneOntologyCellularComponentcytoplasmic periphery of the nuclear pore complex

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.90e-1281466GO:1990723
GeneOntologyCellularComponentnuclear pore cytoplasmic filaments

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.15e-11101466GO:0044614
GeneOntologyCellularComponentannulate lamellae

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.00e-10141466GO:0005642
GeneOntologyCellularComponentnuclear pore nuclear basket

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.81e-09181466GO:0044615
GeneOntologyCellularComponentnuclear inclusion body

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.74e-09201466GO:0042405
GeneOntologyCellularComponentSUMO ligase complex

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

5.21e-09211466GO:0106068
GeneOntologyCellularComponentinclusion body

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 CLU RGPD3

3.23e-06901467GO:0016234
GeneOntologyCellularComponentnuclear pore

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

6.98e-061011467GO:0005643
GeneOntologyCellularComponenttransferase complex

RGPD4 RGPD2 RANBP2 RGPD8 FNTA DTL RGPD1 IFIT5 UBE2D2 UBE2D3 PHF20L1 UBE2D4 RGPD3 FBXO39 ANAPC5 SMURF2 CDC23

4.09e-0496314617GO:1990234
GeneOntologyCellularComponentMon1-Ccz1 complex

CCZ1B CCZ1

4.78e-0451462GO:0035658
GeneOntologyCellularComponentnuclear membrane

RGPD4 RGPD2 RANBP2 RGPD8 DTL RGPD1 UNC50 BROX RGPD3

7.92e-043491469GO:0031965
MousePhenoelevated level of mitotic sister chromatid exchange

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.73e-09161126MP:0003701
MousePhenoabnormal morula morphology

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.67e-08261126MP:0012058
MousePhenoincreased hepatocellular carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 BHMT RGPD3 SMURF2

8.24e-08701128MP:0003331
MousePhenodecreased tumor latency

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.17e-07301126MP:0010308
MousePhenofailure of blastocyst formation

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.45e-07311126MP:0012129
MousePhenoabnormal tumor latency

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.59e-07341126MP:0010307
MousePhenoabnormal blastocyst formation

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

6.08e-07391126MP:0012128
MousePhenoabnormal mitosis

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 CTNND1 PLK4 DYNC1H1

8.47e-071281129MP:0004046
MousePhenoincreased sarcoma incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 PTPRZ1 RGPD3 SMURF2

1.55e-061021128MP:0002032
MousePhenoincreased hepatobiliary system tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 BHMT RGPD3 SMURF2

2.94e-061111128MP:0010297
MousePhenoincreased liver tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 BHMT RGPD3 SMURF2

2.94e-061111128MP:0008019
MousePhenoaneuploidy

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

8.97e-06611126MP:0004024
MousePhenoabnormal eye electrophysiology

RGPD4 RGPD2 RANBP2 RGPD8 LAMA1 RGPD1 BBS2 TTPA GUCA1A RGPD3

1.45e-0522811210MP:0005551
MousePhenoincreased lung carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.72e-05781126MP:0008714
MousePhenoabnormal rod electrophysiology

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 GUCA1A RGPD3

4.70e-051191127MP:0004021
MousePhenoabnormal chromosome number

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

6.46e-05861126MP:0004023
MousePhenoabnormal chromosome morphology

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RAD54L

6.77e-051261127MP:0003702
MousePhenoincreased incidence of induced tumors

RGPD4 RGPD2 RANBP2 ERCC6 RGPD8 RGPD1 EPHA2 RGPD3

7.46e-051731128MP:0002021
MousePhenoabnormal cell nucleus morphology

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 CTNND1 RAD54L

1.15e-041841128MP:0003111
MousePhenoincreased malignant tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 BHMT PTPRZ1 RGPD3 SMURF2

1.20e-042371129MP:0002018
MousePhenoincreased incidence of tumors by chemical induction

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 EPHA2 RGPD3

1.37e-041411127MP:0004499
MousePhenoenlarged epididymis

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.41e-04991126MP:0004931
MousePhenoincreased carcinoma incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 BHMT RGPD3 SMURF2

1.84e-041971128MP:0002038
MousePhenoabnormal spinal cord ventral horn morphology

TTPA DYNC1H1 VEGFA

2.12e-04151123MP:0005112
MousePhenoincreased respiratory system tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.17e-041071126MP:0010298
MousePhenoincreased lung tumor incidence

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.17e-041071126MP:0008014
MousePhenofailure of blastocyst to hatch from the zona pellucida

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.17e-041071126MP:0003694
MousePhenoabnormal blastocyst hatching

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.91e-041131126MP:0003693
MousePhenoabnormal incidence of induced tumors

RGPD4 RGPD2 RANBP2 ERCC6 RGPD8 RGPD1 EPHA2 RGPD3 USP4

3.09e-042691129MP:0013151
MousePhenoabnormal eye physiology

RGPD4 RGPD2 RANBP2 ERCC6 RGPD8 LAMA1 RGPD1 ELP1 BBS2 TTPA GUCA1A CD36 RGPD3 VEGFA

3.39e-0460611214MP:0005253
MousePhenoabnormal preimplantation embryo morphology

RGPD4 RGPD2 RANBP2 RGPD8 LAMA1 RGPD1 TTPA RGPD3 VPS53

4.48e-042831129MP:0014137
MousePhenoincreased physiological sensitivity to xenobiotic

RGPD4 RGPD2 RANBP2 AKT3 RGPD8 RGPD1 ABCB6 EPHA2 RGPD3

4.83e-042861129MP:0008873
MousePhenoretroesophageal right subclavian artery

MYO9A BRD2 VEGFA

6.90e-04221123MP:0004160
DomainRan_BP1

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

1.07e-12121447PF00638
DomainRANBD1

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

1.07e-12121447PS50196
DomainRanBD

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

2.31e-12131447SM00160
DomainRan_bind_dom

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

2.31e-12131447IPR000156
DomainGrip

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

8.47e-11111446SM00755
DomainGRIP

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

8.47e-11111446PF01465
DomainGRIP_dom

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

1.68e-10121446IPR000237
DomainGRIP

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

1.68e-10121446PS50913
DomainRab_bind

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3

5.27e-1071445PF16704
DomainGCC2_Rab_bind

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3

5.27e-1071445IPR032023
Domain-

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3

6.21e-091014451.10.220.60
DomainTPR_REGION

RGPD4 RGPD2 RANBP2 RGPD8 DNAH2 RGPD1 IFIT5 RGPD3 ANAPC5 CDC23 RGPD5

6.22e-0816514411PS50293
DomainTPR

RGPD4 RGPD2 RANBP2 RGPD8 DNAH2 RGPD1 IFIT5 RGPD3 ANAPC5 CDC23 RGPD5

6.22e-0816514411PS50005
DomainTPR-contain_dom

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 IFIT5 RGPD3 ANAPC5 CDC23 RGPD5

2.53e-0715014410IPR013026
DomainTPR

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 IFIT5 RGPD3 ANAPC5 CDC23

7.00e-071291449SM00028
DomainTPR_repeat

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 IFIT5 RGPD3 ANAPC5 CDC23

9.06e-071331449IPR019734
DomainPH_dom-like

RGPD4 RGPD2 RANBP2 AKT3 RGPD8 RGPD1 DOCK10 MYO1B RGPD3 SNTG2 PLEKHH2 ARAP1 ARAP2 FERMT3 RGPD5

1.07e-0642614415IPR011993
DomainTPR-like_helical_dom

RGPD4 UTP6 RGPD2 RANBP2 RGPD8 RGPD1 IFIT5 RGPD3 ANAPC5 CDC23 RGPD5

1.96e-0623314411IPR011990
Domain-

RGPD4 UTP6 RGPD2 RANBP2 RGPD8 RGPD1 IFIT5 RGPD3 ANAPC5 CDC23

4.76e-06207144101.25.40.10
Domainfn3

CNTN4 CRLF1 FNDC1 CSF2RB EBI3 PTPRZ1 EPHA2 ROBO2

3.74e-051621448PF00041
DomainIQ

LRRIQ3 MYO1A MYO9A MYO1B PPEF1 IQGAP1

3.82e-05811446SM00015
Domain-

RGPD4 RGPD2 RANBP2 AKT3 RGPD8 RGPD1 DOCK10 RGPD3 PLEKHH2 ARAP1 ARAP2 FERMT3

5.18e-05391144122.30.29.30
DomainDUF1712

CCZ1B CCZ1

5.90e-0521442PF08217
DomainDUF1712_fun

CCZ1B CCZ1

5.90e-0521442IPR013176
DomainTPR_1

RANBP2 RGPD8 RGPD1 IFIT5 CDC23 RGPD5

6.92e-05901446IPR001440
DomainTPR_1

RANBP2 RGPD8 RGPD1 IFIT5 CDC23 RGPD5

6.92e-05901446PF00515
DomainIQ_motif_EF-hand-BS

LRRIQ3 MYO1A MYO9A MYO1B PPEF1 IQGAP1

6.92e-05901446IPR000048
DomainIQ

LRRIQ3 MYO1A MYO9A MYO1B PPEF1 IQGAP1

8.31e-05931446PS50096
DomainFN3

CNTN4 CRLF1 FNDC1 CSF2RB EBI3 PTPRZ1 EPHA2 ROBO2

9.52e-051851448SM00060
DomainFN3

CNTN4 CRLF1 FNDC1 CSF2RB EBI3 PTPRZ1 EPHA2 ROBO2

1.58e-041991448PS50853
DomainIQ

MYO1A MYO9A MYO1B PPEF1 IQGAP1

2.20e-04711445PF00612
DomainFN3_dom

CNTN4 CRLF1 FNDC1 CSF2RB EBI3 PTPRZ1 EPHA2 ROBO2

2.20e-042091448IPR003961
DomainNebulin

NRAP NEB

3.51e-0441442PF00880
DomainNEBULIN

NRAP NEB

3.51e-0441442PS51216
DomainNEBU

NRAP NEB

3.51e-0441442SM00227
DomainNebulin

NRAP NEB

3.51e-0441442IPR013998
DomainNebulin_repeat

NRAP NEB

3.51e-0441442IPR000900
DomainUBQ-conjugating_AS

UBE2D2 UBE2D3 UBE2D4

9.12e-04251443IPR023313
DomainMyosin_TH1

MYO1A MYO1B

1.21e-0371442PF06017
DomainMyosin_TH1

MYO1A MYO1B

1.21e-0371442IPR010926
DomainPlakophilin/d_Catenin

PKP4 CTNND1

1.21e-0371442IPR028435
DomainTH1

MYO1A MYO1B

1.21e-0371442PS51757
DomainDHC_N1

DNAH2 DYNC1H1

1.60e-0381442PF08385
DomainDynein_heavy_dom-1

DNAH2 DYNC1H1

1.60e-0381442IPR013594
DomainSNF2_N

ERCC6 ATRX RAD54L

1.89e-03321443IPR000330
DomainSNF2_N

ERCC6 ATRX RAD54L

1.89e-03321443PF00176
DomainRA

MYO9A ARAP1 ARAP2

2.66e-03361443PF00788
DomainRA

MYO9A ARAP1 ARAP2

2.88e-03371443PS50200
DomainDHR-1_domain

DOCK4 DOCK10

3.10e-03111442IPR027007
DomainDHR_2

DOCK4 DOCK10

3.10e-03111442PS51651
DomainDHR_1

DOCK4 DOCK10

3.10e-03111442PS51650
DomainDHR-2

DOCK4 DOCK10

3.10e-03111442PF06920
DomainDOCK

DOCK4 DOCK10

3.10e-03111442IPR026791
DomainDOCK_C

DOCK4 DOCK10

3.10e-03111442IPR010703
DomainDOCK-C2

DOCK4 DOCK10

3.10e-03111442PF14429
DomainDHR-2

DOCK4 DOCK10

3.10e-03111442IPR027357
DomainMyosin_head_motor_dom

MYO1A MYO9A MYO1B

3.11e-03381443IPR001609
DomainMYOSIN_MOTOR

MYO1A MYO9A MYO1B

3.11e-03381443PS51456
DomainMyosin_head

MYO1A MYO9A MYO1B

3.11e-03381443PF00063
DomainMYSc

MYO1A MYO9A MYO1B

3.11e-03381443SM00242
DomainUQ_con

UBE2D2 UBE2D3 UBE2D4

3.35e-03391443PF00179
DomainRA_dom

MYO9A ARAP1 ARAP2

3.60e-03401443IPR000159
DomainUBIQUITIN_CONJUGAT_1

UBE2D2 UBE2D3 UBE2D4

3.60e-03401443PS00183
DomainUBIQUITIN_CONJUGAT_2

UBE2D2 UBE2D3 UBE2D4

3.86e-03411443PS50127
DomainUBQ-conjugat_E2

UBE2D2 UBE2D3 UBE2D4

3.86e-03411443IPR000608
DomainRho_GTPase_activation_prot

MYO9A IQGAP1 ARAP1 ARAP2

4.79e-03881444IPR008936
DomainDynein_heavy_chain_D4_dom

DNAH2 DYNC1H1

5.06e-03141442IPR024317
DomainDynein_HC_stalk

DNAH2 DYNC1H1

5.06e-03141442IPR024743
DomainDynein_heavy_dom-2

DNAH2 DYNC1H1

5.06e-03141442IPR013602
DomainDHC_N2

DNAH2 DYNC1H1

5.06e-03141442PF08393
DomainATPase_dyneun-rel_AAA

DNAH2 DYNC1H1

5.06e-03141442IPR011704
DomainMT

DNAH2 DYNC1H1

5.06e-03141442PF12777
DomainAAA_8

DNAH2 DYNC1H1

5.06e-03141442PF12780
DomainCNH

MINK1 NRK

5.06e-03141442SM00036
DomainAAA_5

DNAH2 DYNC1H1

5.06e-03141442PF07728
DomainWW

NEDD4L IQGAP1 SMURF2

5.68e-03471443PF00397
DomainDHC_fam

DNAH2 DYNC1H1

5.80e-03151442IPR026983
DomainDynein_heavy

DNAH2 DYNC1H1

5.80e-03151442PF03028
DomainCNH

MINK1 NRK

5.80e-03151442PF00780
DomainDynein_heavy_dom

DNAH2 DYNC1H1

5.80e-03151442IPR004273
DomainCNH

MINK1 NRK

5.80e-03151442PS50219
DomainCNH_dom

MINK1 NRK

5.80e-03151442IPR001180
DomainPH

AKT3 DOCK10 SNTG2 PLEKHH2 ARAP1 ARAP2 FERMT3

5.85e-032781447SM00233
DomainPH_DOMAIN

AKT3 DOCK10 SNTG2 PLEKHH2 ARAP1 ARAP2 FERMT3

5.96e-032791447PS50003
DomainWW

NEDD4L IQGAP1 SMURF2

6.02e-03481443SM00456
DomainPH_domain

AKT3 DOCK10 SNTG2 PLEKHH2 ARAP1 ARAP2 FERMT3

6.08e-032801447IPR001849
Domain-

UBE2D2 UBE2D3 UBE2D4

7.13e-035114433.10.110.10
DomainWW_DOMAIN_1

NEDD4L IQGAP1 SMURF2

7.13e-03511443PS01159
DomainWW_DOMAIN_2

NEDD4L IQGAP1 SMURF2

7.13e-03511443PS50020
DomainWW_dom

NEDD4L IQGAP1 SMURF2

7.53e-03521443IPR001202
PathwayBIOCARTA_RANBP2_PATHWAY

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.98e-09181136MM1549
PathwayREACTOME_MITOTIC_SPINDLE_CHECKPOINT

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ANAPC5 DYNC1H1 CDC23

3.97e-071171139MM15387
PathwayREACTOME_NUCLEAR_PORE_COMPLEX_NPC_DISASSEMBLY

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

7.14e-07401136MM14945
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_SMALL_RNAS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

8.30e-07411136MM15200
PathwayREACTOME_SUMOYLATION_OF_SUMOYLATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.63e-07421136MM15039
PathwayREACTOME_TRANSPORT_OF_THE_SLBP_DEPENDANT_MATURE_MRNA

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.11e-06431136MM14609
PathwayREACTOME_SUMOYLATION_OF_UBIQUITINYLATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.91e-06471136MM14939
PathwayREACTOME_GENE_SILENCING_BY_RNA

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.45e-06491136MM14837
PathwayREACTOME_TRANSPORT_OF_MATURE_MRNAS_DERIVED_FROM_INTRONLESS_TRANSCRIPTS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.77e-06501136MM14610
PathwayREACTOME_SUMOYLATION_OF_DNA_REPLICATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.12e-06511136MM15151
PathwayREACTOME_NUCLEAR_ENVELOPE_BREAKDOWN

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.89e-06551136MM14917
PathwayREACTOME_TRANSPORT_OF_MATURE_TRANSCRIPT_TO_CYTOPLASM

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 SLU7 RGPD3

5.62e-06861137MM15413
PathwayREACTOME_SUMOYLATION_OF_RNA_BINDING_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

6.69e-06581136MM15149
PathwayREACTOME_SNRNP_ASSEMBLY

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

6.69e-06581136MM14736
PathwayREACTOME_CELLULAR_RESPONSES_TO_STIMULI

RGPD4 RGPD2 SIN3B RANBP2 AKT3 RGPD8 MINK1 RGPD1 CREBRF UBE2D2 UBE2D3 RGPD3 ANAPC5 DYNC1H1 CDC23

1.19e-0550511315MM15548
PathwayREACTOME_SUMOYLATION_OF_CHROMATIN_ORGANIZATION_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.30e-05651136MM15147
PathwayREACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 DYNC1H1

1.53e-051001137MM14561
PathwayREACTOME_SEPARATION_OF_SISTER_CHROMATIDS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ANAPC5 DYNC1H1 CDC23

2.46e-051931139MM14890
PathwayREACTOME_REGULATION_OF_HSF1_MEDIATED_HEAT_SHOCK_RESPONSE

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.55e-05731136MM14948
PathwayREACTOME_GLUCOSE_METABOLISM

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.95e-05821136MM15394
PathwayREACTOME_SUMOYLATION_OF_DNA_DAMAGE_RESPONSE_AND_REPAIR_PROTEINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

5.68e-05841136MM14929
PathwayREACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 DYNC1H1

7.89e-051291137MM14894
PathwayREACTOME_CELLULAR_RESPONSE_TO_HEAT_STRESS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

9.45e-05921136MM14951
PathwayKEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS

NEDD4L UBE2D2 UBE2D3 UBE2D4 ANAPC5 SMURF2 CDC23

1.05e-041351137M15247
PathwayREACTOME_MITOTIC_METAPHASE_AND_ANAPHASE

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ANAPC5 DYNC1H1 CDC23

1.10e-042341139MM14898
PathwayREACTOME_RHO_GTPASES_ACTIVATE_FORMINS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 DYNC1H1

1.38e-041411137MM15266
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

RGPD4 DOCK4 RGPD2 RANBP2 RGPD8 MYO9A PKP4 RGPD1 DOCK10 IQGAP1 EPHA2 RGPD3 DYNC1H1 ARAP1 ARAP2

2.06e-0464911315MM15690
PathwayREACTOME_MITOTIC_PROMETAPHASE

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 PLK4 DYNC1H1

2.19e-042021138MM15362
PathwayREACTOME_MITOTIC_PROPHASE

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.07e-041141136MM15361
PathwayREACTOME_CELL_CYCLE_CHECKPOINTS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ANAPC5 DYNC1H1 CDC23

3.28e-042711139MM15388
PathwayREACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 SLU7 PRPF8 CWC22 RGPD3

3.85e-042771139MM15414
PathwayWP_BURN_WOUND_HEALING

LAMA1 FGF2 VEGFA

6.00e-04211133MM15978
PathwayREACTOME_DOWNREGULATION_OF_SMAD2_3_SMAD4_TRANSCRIPTIONAL_ACTIVITY

NEDD4L UBE2D3 SMURF2

8.98e-04241133MM14877
PathwayREACTOME_RHO_GTPASE_EFFECTORS

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 IQGAP1 RGPD3 DYNC1H1

1.08e-032571138MM14755
PathwayREACTOME_M_PHASE

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 ANAPC5 PLK4 DYNC1H1 CDC23

1.09e-0338711310MM15364
Pubmed

Interconversion of red opsin isoforms by the cyclophilin-related chaperone protein Ran-binding protein 2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-14714669037092
Pubmed

Complex genomic rearrangements lead to novel primate gene function.

RGPD4 RGPD2 RGPD8 RGPD1 RGPD3 RGPD5

3.44e-147146615710750
Pubmed

Genomic organization, expression, and localization of murine Ran-binding protein 2 (RanBP2) gene.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146611353387
Pubmed

Microglial activation in an amyotrophic lateral sclerosis-like model caused by Ranbp2 loss and nucleocytoplasmic transport impairment in retinal ganglion neurons.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146630944974
Pubmed

Nucleoporin Nup358 drives the differentiation of myeloid-biased multipotent progenitors by modulating HDAC3 nuclear translocation.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146638838144
Pubmed

Retina-specifically expressed novel subtypes of bovine cyclophilin.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-14714667559465
Pubmed

Mst1, RanBP2 and eIF4G are new markers for in vivo PI3K activation in murine and human prostate.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146617372272
Pubmed

Proteostatic Remodeling of Small Heat Shock Chaperones─Crystallins by Ran-Binding Protein 2─and the Peptidyl-Prolyl cis-trans Isomerase and Chaperone Activities of Its Cyclophilin Domain.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146638657106
Pubmed

Nup358, a nucleoporin, functions as a key determinant of the nuclear pore complex structure remodeling during skeletal myogenesis.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146621205196
Pubmed

Haploinsufficiency of RanBP2 is neuroprotective against light-elicited and age-dependent degeneration of photoreceptor neurons.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146618949001
Pubmed

Selective impairment of a subset of Ran-GTP-binding domains of ran-binding protein 2 (Ranbp2) suffices to recapitulate the degeneration of the retinal pigment epithelium (RPE) triggered by Ranbp2 ablation.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146625187515
Pubmed

Localization of the Ran-GTP binding protein RanBP2 at the cytoplasmic side of the nuclear pore complex.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-14714668603673
Pubmed

Uncoupling phototoxicity-elicited neural dysmorphology and death by insidious function and selective impairment of Ran-binding protein 2 (Ranbp2).

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146626632511
Pubmed

Differential loss of prolyl isomerase or chaperone activity of Ran-binding protein 2 (Ranbp2) unveils distinct physiological roles of its cyclophilin domain in proteostasis.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146624403063
Pubmed

Distinct and atypical intrinsic and extrinsic cell death pathways between photoreceptor cell types upon specific ablation of Ranbp2 in cone photoreceptors.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146623818861
Pubmed

Kinesin-1 and mitochondrial motility control by discrimination of structurally equivalent but distinct subdomains in Ran-GTP-binding domains of Ran-binding protein 2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146623536549
Pubmed

Identification of RanBP2- and kinesin-mediated transport pathways with restricted neuronal and subcellular localization.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146612191015
Pubmed

Ranbp2 haploinsufficiency mediates distinct cellular and biochemical phenotypes in brain and retinal dopaminergic and glia cells elicited by the Parkinsonian neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146622821000
Pubmed

Neuroprotection resulting from insufficiency of RANBP2 is associated with the modulation of protein and lipid homeostasis of functionally diverse but linked pathways in response to oxidative stress.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.44e-147146620682751
Pubmed

Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.

RGPD4 RGPD2 RANBP2 RGPD8 LAMA1 RGPD1 RGPD3

1.24e-1315146714697343
Pubmed

The nucleoporin RanBP2 tethers the cAMP effector Epac1 and inhibits its catalytic activity.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.37e-138146621670213
Pubmed

Critical role of RanBP2-mediated SUMOylation of Small Heterodimer Partner in maintaining bile acid homeostasis.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.37e-138146627412403
Pubmed

Mice lacking Ran binding protein 1 are viable and show male infertility.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.37e-138146621310149
Pubmed

The distribution of phosphorylated SR proteins and alternative splicing are regulated by RANBP2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.37e-138146622262462
Pubmed

Zap70 and downstream RanBP2 are required for the exact timing of the meiotic cell cycle in oocytes.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.37e-138146628745977
Pubmed

Resolution of sister centromeres requires RanBP2-mediated SUMOylation of topoisomerase IIalpha.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.10e-139146618394993
Pubmed

Loss of Ranbp2 in motoneurons causes disruption of nucleocytoplasmic and chemokine signaling, proteostasis of hnRNPH3 and Mmp28, and development of amyotrophic lateral sclerosis-like syndromes.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.10e-139146628100513
Pubmed

Association of the kinesin-binding domain of RanBP2 to KIF5B and KIF5C determines mitochondria localization and function.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.10e-139146617887960
Pubmed

The docking of kinesins, KIF5B and KIF5C, to Ran-binding protein 2 (RanBP2) is mediated via a novel RanBP2 domain.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.10e-139146611553612
Pubmed

The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.10e-139146610601307
Pubmed

The cyclophilin-like domain mediates the association of Ran-binding protein 2 with subunits of the 19 S regulatory complex of the proteasome.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.10e-13914669733766
Pubmed

Impairments in age-dependent ubiquitin proteostasis and structural integrity of selective neurons by uncoupling Ran GTPase from the Ran-binding domain 3 of Ranbp2 and identification of novel mitochondrial isoforms of ubiquitin-conjugating enzyme E2I (ubc9) and Ranbp2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

4.10e-139146628877029
Pubmed

The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.02e-1210146627160050
Pubmed

Parkin ubiquitinates and promotes the degradation of RanBP2.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.02e-1210146616332688
Pubmed

Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.02e-121014668857542
Pubmed

Ran-dependent docking of importin-beta to RanBP2/Nup358 filaments is essential for protein import and cell viability.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.02e-1210146621859863
Pubmed

RanBP2 modulates Cox11 and hexokinase I activities and haploinsufficiency of RanBP2 causes deficits in glucose metabolism.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.24e-1211146617069463
Pubmed

An Rtn4/Nogo-A-interacting micropeptide modulates synaptic plasticity with age.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.24e-1211146635771867
Pubmed

T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

2.24e-1211146634110283
Pubmed

Ankyrin-G induces nucleoporin Nup358 to associate with the axon initial segment of neurons.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

8.26e-1213146631427429
Pubmed

Systematic identification of factors for provirus silencing in embryonic stem cells.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 ELP1 PRPF8 RGPD3 EIF3D ANAPC5 CDC23

5.46e-111531461126365490
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RGPD4 RGPD2 RANBP2 RGPD8 MYO1A ATRX DTL DNAH2 RGPD1 IFIT5 GRIA1 MYO1B NEB PRPF8 IQGAP1 CREBRF BRD2 WDR75 PHF20L1 RGPD3 SUPT16H ALDH1B1 SMURF2 DOP1A PHTF1 RGPD5

3.33e-1014421462635575683
Pubmed

Terminal differentiation of cortical neurons rapidly remodels RanGAP-mediated nuclear transport system.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

3.48e-1022146627717094
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

RGPD4 RGPD2 RANBP2 RGPD8 MYO9A PKP4 RPS10 RGPD1 NEB PRPF8 IQGAP1 UBE2D2 UBE2D3 UBE2D4 CLU RGPD3 EIF3D CTNND1 DYNC1H1 RGPD5

4.63e-108441462025963833
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

RGPD4 CNTN4 RGPD2 SIN3B RANBP2 NEDD4L RGPD8 PKP4 MINK1 RGPD1 GRIA1 IQGAP1 CLU RGPD3 SUPT16H ZSCAN18 LRP1 CTNND1 DYNC1H1 FERMT3

4.39e-099631462028671696
Pubmed

Peering through the pore: nuclear pore complex structure, assembly, and function.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.22e-0838146612791264
Pubmed

Comprehensive identification of phosphorylation sites in postsynaptic density preparations.

RGPD4 RGPD2 RANBP2 RGPD8 ATRX PKP4 RGPD1 CLU PTPRZ1 RGPD3

5.53e-082311461016452087
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

RGPD4 RGPD2 RANBP2 RGPD8 ATRX RGPD1 RGPD3

8.10e-0886146737253089
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RGPD4 RGPD2 RANBP2 RGPD8 DTL RGPD1 PRPF8 CWC22 IQGAP1 CRY2 PHF20L1 CLU RGPD3 EIF3D ANAPC5 PLK4 DYNC1H1 ARAP1 CDC23 RGPD5

8.75e-0811551462020360068
Pubmed

Interaction of Sox2 with RNA binding proteins in mouse embryonic stem cells.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 PRPF8 RGPD3 SUPT16H

1.12e-07135146831077711
Pubmed

The UbL protein UBTD1 stably interacts with the UBE2D family of E2 ubiquitin conjugating enzymes.

RANBP2 UBE2D2 UBE2D3 UBE2D4

1.44e-0712146424211586
Pubmed

Insights into specificity, redundancy and new cellular functions of C/EBPa and C/EBPb transcription factors through interactome network analysis.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 IQGAP1 RGPD3

2.14e-0799146727746211
Pubmed

Blockade of EphA receptor tyrosine kinase activation inhibits vascular endothelial cell growth factor-induced angiogenesis.

EPHA2 FGF2 VEGFA

2.89e-074146312496364
Pubmed

Identification of a novel Ran binding protein 2 related gene (RANBP2L1) and detection of a gene cluster on human chromosome 2q11-q12.

RANBP2 RGPD8 RGPD5

2.89e-07414639480752
Pubmed

Biological insights from 108 schizophrenia-associated genetic loci.

CNTN4 AKT3 LRRIQ3 MYO1A ACTR5 GRIA1 SLC35G2 CLU LRP1 CTNND1

6.77e-073031461025056061
Pubmed

The RING-H2 protein RNF11 is overexpressed in breast cancer and is a target of Smurf2 E3 ligase.

UBE2D2 UBE2D3 SMURF2

7.20e-075146314562029
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

RGPD4 RGPD2 RANBP2 RGPD8 RPS10 RGPD1 MYO1B PRPF8 IQGAP1 BRD2 RGPD3 SUPT16H EIF3D DYNC1H1

9.05e-076651461430457570
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

CCZ1B RANBP2 ATRX ELP1 SRP19 PRPF8 IQGAP1 BRD2 CCZ1 CTNND1 DYNC1H1 ARAP1 CDC23

1.18e-065821461320467437
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

RGPD4 RGPD2 CCZ1B RANBP2 RGPD8 DTL RPS10 RGPD1 ELP1 MYO1B PRPF8 WDR75 CCZ1 RGPD3 ALDH1B1 CTNND1 DYNC1H1 CDC23 RGPD5

1.45e-0612571461937317656
Pubmed

Synergy between Kaposi's sarcoma-associated herpesvirus (KSHV) vIL-6 and HIV-1 Nef protein in promotion of angiogenesis and oncogenesis: role of the AKT signaling pathway.

AKT3 FGF2 VEGFA

2.51e-067146323604117
Pubmed

Lys-63-linked ubiquitination by E3 ubiquitin ligase Nedd4-1 facilitates endosomal sequestration of internalized α-synuclein.

NEDD4L UBE2D2 UBE2D3

2.51e-067146324831002
Pubmed

The IDOL-UBE2D complex mediates sterol-dependent degradation of the LDL receptor.

UBE2D2 UBE2D3 UBE2D4

2.51e-067146321685362
Pubmed

Lysine 63-linked polyubiquitination of the dopamine transporter requires WW3 and WW4 domains of Nedd4-2 and UBE2D ubiquitin-conjugating enzymes.

NEDD4L UBE2D2 UBE2D3

2.51e-067146320051513
Pubmed

Monoubiquitination promotes calpain cleavage of the protein phosphatase 2A (PP2A) regulatory subunit α4, altering PP2A stability and microtubule-associated protein phosphorylation.

PTPA UBE2D2 UBE2D3

2.51e-067146322613722
Pubmed

Analysis of the Zn-Binding Domains of TRIM32, the E3 Ubiquitin Ligase Mutated in Limb Girdle Muscular Dystrophy 2H.

UBE2D2 UBE2D3 UBE2D4

2.51e-067146330884854
Pubmed

Structure of a ubiquitin-loaded HECT ligase reveals the molecular basis for catalytic priming.

NEDD4L UBE2D3 SMURF2

2.51e-067146323644597
Pubmed

The E3 Ubiquitin Ligase NEDD4L Targets OGG1 for Ubiquitylation and Modulates the Cellular DNA Damage Response.

NEDD4L UBE2D2 UBE2D3

2.51e-067146333282879
Pubmed

A proteomics approach for the identification of cullin-9 (CUL9) related signaling pathways in induced pluripotent stem cell models.

PRPF8 ANAPC5 DYNC1H1 CDC23

2.97e-0624146433705438
Pubmed

Structure and catalytic activation of the TRIM23 RING E3 ubiquitin ligase.

UBE2D2 UBE2D3 UBE2D4

4.00e-068146328681414
Pubmed

The mechanism of neural precursor cell expressed developmentally down-regulated 4-2 (Nedd4-2)/NEDD4L-catalyzed polyubiquitin chain assembly.

NEDD4L UBE2D2 UBE2D3

4.00e-068146328972136
Pubmed

Ube2W conjugates ubiquitin to α-amino groups of protein N-termini.

UBE2D2 UBE2D3 UBE2D4

4.00e-068146323560854
Pubmed

Ubiquitination of alpha-synuclein filaments by Nedd4 ligases.

NEDD4L UBE2D3 SMURF2

4.00e-068146330021006
Pubmed

MID1 catalyzes the ubiquitination of protein phosphatase 2A and mutations within its Bbox1 domain disrupt polyubiquitination of alpha4 but not of PP2Ac.

PTPA UBE2D2 UBE2D3

4.00e-068146325207814
Pubmed

Hypermutation of immunoglobulin genes in memory B cells of DNA repair-deficient mice.

ERCC6 ATRX RAD54L

4.00e-06814639607915
Pubmed

The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome.

PRPF8 UBE2D3 USP4

4.00e-068146320595234
Pubmed

Inhibition of UVSSA ubiquitination suppresses transcription-coupled nucleotide excision repair deficiency caused by dissociation from USP7.

UBE2D2 UBE2D3 UBE2D4

4.00e-068146329323787
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 SLU7 IQGAP1 WDR75 RGPD3 DYNC1H1

4.04e-063701461022922362
Pubmed

System-Wide Modulation of HECT E3 Ligases with Selective Ubiquitin Variant Probes.

NEDD4L UBE2D2 UBE2D3 SMURF2

4.15e-0626146426949039
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

UTP6 RANBP2 ERCC6 MYO9A PKP4 RPS10 DOCK10 ELP1 SLU7 MYO1B PRPF8 IQGAP1 MEMO1 WDR75 SUPT16H EIF3D ALDH1B1 CTNND1 DYNC1H1

4.22e-0613531461929467282
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 CLU RGPD3 GOT1

5.48e-06226146837839992
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

RGPD8 DDX60 MINK1 LAMA1 MYO1B NEB PRPF8 SUPT16H

7.07e-06234146836243803
Pubmed

Inflammasome activation and metabolic remodelling in p16-positive aging cells aggravates high-fat diet-induced lung fibrosis by inhibiting NEDD4L-mediated K48-polyubiquitin-dependent degradation of SGK1.

NEDD4L UBE2D2 UBE2D3

8.51e-0610146337345264
Pubmed

Mechanism and chain specificity of RNF216/TRIAD3, the ubiquitin ligase mutated in Gordon Holmes syndrome.

UBE2D2 UBE2D3 UBE2D4

8.51e-0610146331087003
Pubmed

Osmotic and heat stress-dependent regulation of MLK4β and MLK3 by the CHIP E3 ligase in ovarian cancer cells.

UBE2D2 UBE2D3 UBE2D4

8.51e-0610146328757353
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

UTP6 RANBP2 RPS10 ELP1 SRP19 PRPF8 IQGAP1 MEMO1 RGPD3 SUPT16H EIF3D DYNC1H1 CDC23

9.27e-067041461329955894
Pubmed

Genome-wide association study identifies loci influencing concentrations of liver enzymes in plasma.

HNF1A NEDD4L PPP1R3B MYO1B EPHA2

1.03e-0568146522001757
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

SIN3B RANBP2 IFIT5 PRPF8 RBM27 EPHA2 CTNND1 DYNC1H1

1.36e-05256146833397691
Pubmed

Basic fibroblast growth factor induces VEGF expression in chondrosarcoma cells and subsequently promotes endothelial progenitor cell-primed angiogenesis.

FGF2 VEGFA

1.75e-052146225735814
Pubmed

Pro-neoangiogenic cytokines (VEGF and bFGF) and anemia in solid tumor patients.

FGF2 VEGFA

1.75e-052146215756443
Pubmed

Accumulation of p53 via down-regulation of UBE2D family genes is a critical pathway for cadmium-induced renal toxicity.

UBE2D2 UBE2D4

1.75e-052146226912277
Pubmed

[Expression and clinical significance of serum VEGF and bFGF in children with acute leukemia].

FGF2 VEGFA

1.75e-052146222125837
Pubmed

Epilepsy-associated gene Nedd4-2 mediates neuronal activity and seizure susceptibility through AMPA receptors.

NEDD4L GRIA1

1.75e-052146228212375
Pubmed

Dual blockade of vascular endothelial growth factor (VEGF) and basic fibroblast growth factor (FGF-2) exhibits potent anti-angiogenic effects.

FGF2 VEGFA

1.75e-052146227130666
Pubmed

[The significance of VEGF siRNA and bFGF siRNA in invasion and proliferation of pancreatic carcinoma cell].

FGF2 VEGFA

1.75e-052146220646480
Pubmed

Mutant Cockayne syndrome group B protein inhibits repair of DNA topoisomerase I-DNA covalent complex.

ERCC6 PGBD3

1.75e-052146221143350
Pubmed

Cell injury unmasks a latent proangiogenic phenotype in mice with increased expression of FGF2 in the retina.

FGF2 VEGFA

1.75e-052146210942527
Pubmed

Serum levels of VEGF and bFGF in hypoxic patients with exacerbated COPD.

FGF2 VEGFA

1.75e-052146220504760
Pubmed

bFGF and VEGF improve the quality of vitrified-thawed human ovarian tissues after xenotransplantation to SCID mice.

FGF2 VEGFA

1.75e-052146226712576
Pubmed

[Prediction of the effect of neoadjuvant chemotherapy in patients with non-small cell lung cancer of stage III at phases of combined treatment].

FGF2 VEGFA

1.75e-052146230475537
Pubmed

Development and characterisation of SMURF2-targeting modifiers.

UBE2D3 SMURF2

1.75e-052146233430646
InteractionRGPD4 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

1.34e-10221457int:RGPD4
InteractionRGPD2 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

6.79e-10271457int:RGPD2
InteractionRGPD3 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

4.27e-08471457int:RGPD3
InteractionRGPD1 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

5.76e-08491457int:RGPD1
InteractionMCM2 interactions

RGPD4 RGPD2 RANBP2 RGPD8 ATRX MYO9A TNIP2 PKP4 RPS10 RGPD1 ELP1 NEB IQGAP1 UBE2D2 UBE2D3 UBE2D4 CLU EPHA2 RGPD3 SUPT16H EIF3D CTNND1 DYNC1H1 RGPD5

7.90e-07108114524int:MCM2
InteractionRGPD8 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

1.04e-06741457int:RGPD8
InteractionRCC1 interactions

RANBP2 ERCC6 RGPD8 ATRX TNIP2 RGPD1 BRD2 RGPD3 USP4 RGPD5

2.00e-0620114510int:RCC1
InteractionRGPD5 interactions

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3 RGPD5

6.03e-06961457int:RGPD5
InteractionNPIPB6 interactions

RANBP2 RGPD8 RGPD1 RGPD5

7.27e-06181454int:NPIPB6
InteractionRANBP2 interactions

RGPD4 RGPD2 RANBP2 RGPD8 TNIP2 RGPD1 PRPF8 CRY2 RGPD3 SUPT16H USP4 RGPD5

1.21e-0536114512int:RANBP2
InteractionUSP7 interactions

ERCC6 NEDD4L RGPD8 ATRX DDX60 TNIP2 PKP4 MINK1 LAMA1 DOCK10 FTSJ1 MYO1B RENBP NEB PRPF8 CWC22 IQGAP1 CRY2 UBE2D3 SUPT16H FGF2 FBXO39 VPS53 DYNC1H1

2.17e-05131314524int:USP7
InteractionEIF3K interactions

DDX60 TNIP2 RPS10 SRP19 PRPF8 BRD2 EIF3D DYNC1H1

3.39e-051711458int:EIF3K
InteractionMYLIP interactions

TNIP2 ARID5A UBE2D2 UBE2D3 UBE2D4

5.12e-05561455int:MYLIP
InteractionCHFR interactions

RANBP2 UBE2D2 UBE2D3 UBE2D4 LRP1

7.15e-05601455int:CHFR
InteractionRNF111 interactions

UBE2D2 UBE2D3 BRD2 UBE2D4 RBM27 SMURF2

7.22e-05971456int:RNF111
InteractionARK2C interactions

UBE2D2 UBE2D3 UBE2D4

7.65e-05121453int:ARK2C
InteractionRMC1 interactions

CCZ1B RANBP2 IQGAP1 MEMO1 CCZ1 CTNND1 DYNC1H1

1.17e-041521457int:RMC1
InteractionUBXN6 interactions

UTP6 RGPD8 ACTR5 MYO9A CCZ1 USP4 ANAPC5 ARAP1 CDC23 RGPD5

1.25e-0432514510int:UBXN6
InteractionZNRF1 interactions

BHMT UBE2D2 UBE2D3 UBE2D4

1.27e-04361454int:ZNRF1
InteractionUVSSA interactions

ERCC6 UBE2D2 UBE2D3 UBE2D4

1.41e-04371454int:UVSSA
GeneFamilyTetratricopeptide repeat domain containing|Bardet-Biedl syndrome associated|BBSome

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 IFIT5 RGPD3 CDC23 RGPD5

1.73e-081151029769
GeneFamilyFibronectin type III domain containing

CNTN4 CRLF1 FNDC1 CSF2RB EBI3 PTPRZ1 EPHA2 ROBO2

3.42e-061601028555
GeneFamilyMyosins, class I

MYO1A MYO1B

8.63e-04810221097
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

AKT3 DOCK10 PLEKHH2 ARAP1 ARAP2 FERMT3

1.11e-032061026682
GeneFamilyUbiquitin conjugating enzymes E2

UBE2D2 UBE2D3 UBE2D4

1.59e-03411023102
GeneFamilyAnaphase promoting complex |Tetratricopeptide repeat domain containing

ANAPC5 CDC23

2.74e-03141022402
CoexpressionGAUSSMANN_MLL_AF4_FUSION_TARGETS_B_UP

RGPD4 RGPD2 RANBP2 CRLF1 RGPD8 RGPD1 RGPD3

4.94e-10331447MM477
CoexpressionTABULA_MURIS_SENIS_TRACHEA_GRANULOCYTE_AGEING

RGPD4 RGPD2 RANBP2 RGPD8 RGPD1 RGPD3

1.28e-07431446MM3857
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL3

CNTN4 GALC DCDC1 ACSS1 GRIA1 SLC35G2 MEMO1 CLU CD36 MKX LRP1 PLEKHH2 AGBL2 ARAP2

3.62e-0657414414M39056
CoexpressionNAKAYA_PBMC_FLUARIX_FLUVIRIN_AGE_18_50YO_CORRELATED_WITH_HAI_28DY_RESPONSE_AT_7DY_NEGATIVE

RGPD4 RGPD2 RANBP2 AKT3 RGPD8 RGPD1 UBE2D3 WDR75 PHF20L1 RGPD3 IFT80 RGPD5

1.28e-0547414412M40991
CoexpressionGSE28737_WT_VS_BCL6_KO_MARGINAL_ZONE_BCELL_DN

DOCK4 RANBP2 STXBP5L PPP1R3B PHF20L1 RBM27 GOT1 PHTF1

1.44e-051981448M9346
CoexpressionGSE6090_UNSTIM_VS_DC_SIGN_STIM_DC_UP

DTL RENBP USP4 CDYL CTNND1 ANAPC5 SMURF2

3.82e-051661447M6811
CoexpressionKAUFFMANN_DNA_REPAIR_GENES

ERCC6 ATRX TEP1 CRY2 UBE2D2 UBE2D3 SUPT16H RAD54L

4.21e-052301448M11563
CoexpressionMEBARKI_HCC_PROGENITOR_FZD8CRD_DN

DOCK4 SEC16B HNF1A DCDC1 PPP1R3B MAN1C1 ACSS1 NEB ARID5A AGBL2 VEGFA

4.88e-0545914411M38993
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_100

DOCK4 CNTN4 ANO1 COL6A5 ALDH1B1

2.37e-06331405gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_100
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500

DOCK4 CNTN4 LAMA1 ANO1 COL6A5 RUNX1T1 CWC22 CLU NRK LRP1 ROBO2 ALDH1B1

6.83e-0637214012gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

LAMA1 DOCK10 RUNX1T1 CWC22 CLU NRK LRP1 GLIPR2 SORCS3 ROBO2 ALDH1B1 PLEKHH2

7.02e-0637314012gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_100

DOCK4 CNTN4 ANO1 COL6A5 NRK ALDH1B1

1.48e-05801406gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_100
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000

DOCK4 CNTN4 MYO9A LAMA1 ANO1 COL6A5 RUNX1T1 CWC22 CLU NRK ZSCAN18 LRP1 GLIPR2 ROBO2 ALDH1B1 PLEKHH2 VEGFA

2.04e-0579714017gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_2500_k-means-cluster#3

AKT3 ERCC6 NEDD4L STXBP5L ACSS1 ANO1 NEB CWC22 SIRT4 CREBRF SLCO5A1 CLIC5 PTPRZ1 SUPT16H TSPAN13 SORCS3 PLK4 PHTF1

2.43e-0589314018Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_2500_K3
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_top-relative-expression-ranked_1000

DOCK4 CNTN4 ERCC6 LAMA1 DOCK10 RUNX1T1 CWC22 CREBRF CLU NRK ZSCAN18 LRP1 GLIPR2 ROBO2 ALDH1B1 PLEKHH2 VEGFA

4.51e-0584914017gudmap_dev gonad_e11.5_M_GonMes_Sma_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_200

DOCK4 CNTN4 ANO1 COL6A5 NRK ROBO2 ALDH1B1

4.62e-051431407gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500

DOCK4 CNTN4 LAMA1 ANO1 COL6A5 CLU NRK ZSCAN18 LRP1 ROBO2 ALDH1B1

5.07e-0538514011gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

DOCK4 CNTN4 MYO1A LAMA1 DOCK10 RUNX1T1 CWC22 CLU NRK LRP1 GLIPR2 SORCS3 ROBO2 ALDH1B1 PLEKHH2 VEGFA

7.01e-0579314016gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

DOCK4 CNTN4 MYO1A LAMA1 ANO1 COL6A5 RUNX1T1 CWC22 CLU NRK LRP1 ROBO2 SCPEP1 ALDH1B1 PLEKHH2 VEGFA

7.44e-0579714016gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000

RANBP2 CRLF1 NEDD4L DIS3L STXBP5L PPP1R3B ACSS1 ANO1 CWC22 SIRT4 UBE2D2 CLIC5 RBM27 PTPRZ1 NRK FGF2 ARAP2 DOP1A

8.40e-0598314018Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_500

DOCK4 CNTN4 MYO9A DTL LAMA1 DOCK10 NRK LRP1 ROBO2 PLEKHH2 VEGFA

1.05e-0441814011gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_200

CNTN4 ANO1 COL6A5 ALDH1B1

1.38e-04401404gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_k2_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

LAMA1 RUNX1T1 CWC22 CLU NRK LRP1 SORCS3 ROBO2 ALDH1B1 PLEKHH2

1.45e-0436114010gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#4

CNTN4 CRLF1 DNAH2 DOCK10 FNDC1 CSF2RB CLU NRK FGF2

1.65e-042981409Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K4
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_1000

CNTN4 MYO1A MYO9A LAMA1 DOCK10 RUNX1T1 TMEM260 CLU NRK LRP1 GLIPR2 ROBO2 ALDH1B1 PLEKHH2 VEGFA

1.70e-0476814015gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000

MYO1A LAMA1 ANO1 RUNX1T1 CWC22 CLU NRK MKX LRP1 GLIPR2 SORCS3 ROBO2 ALDH1B1 PLEKHH2 VEGFA

1.93e-0477714015gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

MAN1C1 DDX60 DOCK10 ANO1 COL6A5 CREBRF CLU PTPRZ1 CD36 MKX LRP1 FGF2 PLEKHH2 ANGPTL7 ARAP2

1.96e-0477814015gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#4

CNTN4 CRLF1 DNAH2 DOCK10 ABCB6 FNDC1 CSF2RB FGF2

2.02e-042411408Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_1000_K4
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_1000_k-means-cluster#5

CNTN4 CRLF1 DNAH2 DOCK10 FNDC1 CSF2RB NRK FGF2

2.20e-042441408Facebase_RNAseq_e9.5_Olfactory Placode_1000_K5
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

LAMA1 RUNX1T1 LRP1 GLIPR2 SORCS3 ROBO2

2.25e-041301406gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000

CNTN4 CRLF1 STXBP5L PPP1R3B TNIP2 DNAH2 DOCK10 SIRT4 CREBRF SLCO5A1 FNDC1 CSF2RB NRK MKX FGF2 SORCS3 DOP1A

2.34e-0497314017Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_1000
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#3

CNTN4 CRLF1 DNAH2 DOCK10 ABCB6 RUNX1T1 FNDC1 CSF2RB NRK FGF2

2.38e-0438414010Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_500_k-means-cluster#3

CNTN4 CRLF1 DNAH2 DOCK10 FNDC1 CSF2RB NRK FGF2

2.52e-042491408Facebase_RNAseq_e8.5_Paraxial Mesoderm_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Central Eminence_top-relative-expression-ranked_1000

AKT3 ERCC6 NEDD4L ATRX STXBP5L ACSS1 ANO1 ABCB6 CWC22 SLCO5A1 FNDC1 CLIC5 SUPT16H TSPAN13 PLK4 GOT1 PHTF1

2.73e-0498614017Facebase_RNAseq_e10.5_Neural Epithelium Overlying Central Eminence_1000
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_500

CNTN4 CRLF1 PPP1R3B DNAH2 DOCK10 ANO1 GRIA1 FNDC1 CSF2RB NRK FGF2

3.41e-0447914011Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

RANBP2 NEDD4L ATRX MYO9A STXBP5L UNC50 CLIC5 PTPRZ1 SUPT16H TSPAN13 ROBO2 SCPEP1 IFT80 ANAPC5 VPS53

3.95e-0483114015Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ Genital tubercle_emap-6706_k-means-cluster#2_top-relative-expression-ranked_200

CRLF1 RUNX1T1 SLCO5A1 MKX

4.43e-04541404gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle_200_k2
CoexpressionAtlasFacebaseRNAseq_e10.5_Olfactory Pit_top-relative-expression-ranked_1000_k-means-cluster#5

CNTN4 CRLF1 DNAH2 DOCK10 FNDC1 CSF2RB NRK FGF2

5.01e-042761408Facebase_RNAseq_e10.5_Olfactory Pit_1000_K5
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_200

DOCK4 CNTN4 MYO9A ANO1 NRK ALDH1B1

5.20e-041521406gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_200
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 LAMA1 COL6A5 PTPRZ1 MKX TDRD6 HEPHL1 PLEKHH2

5.96e-081601468c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 LAMA1 COL6A5 PTPRZ1 MKX TDRD6 HEPHL1 PLEKHH2

5.96e-08160146825c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 FGF2 SORCS3 PLEKHH2 VEGFA

2.24e-07190146845df8fee00f8949937863159d7aa042e72748d9b
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MYO9A ACSS1 PKP4 LAMA1 NEB NRK PLEKHH2 VEGFA

2.42e-071921468ee27d27e3d269764dbe8711d0b37ff9331a298a9
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DOCK4 CNTN4 LAMA1 COL6A5 LRP1 SORCS3 PLEKHH2 VEGFA

3.30e-0720014689b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCellControl-Epithelial_cells-AT1|Control / group, cell type (main and fine annotations)

DOCK4 NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

1.77e-061741467548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCellwk_15-18-Mesenchymal-Chondrocyte-ASPN+_chondrocyte|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

RGPD2 TEP1 FNDC1 CLU PTPRZ1 NRK RGPD3

2.06e-061781467a55130670aa95a87b833dd3cd2de461d779e4c06
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NEDD4L MYO1B CLIC5 TSPAN13 CTNND1 ARAP2 VEGFA

2.56e-06184146757c792e6e2fedba25d3350ffe649fd74750b579d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D122|Adult / Lineage, Cell type, age group and donor

CNTN4 NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

2.56e-061841467561592edc3083fad41b91811151b442207c65dd9
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NEDD4L MYO1B CLIC5 TSPAN13 CTNND1 ARAP2 VEGFA

2.56e-061841467d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1|Adult / Lineage, Cell type, age group and donor

CNTN4 NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

2.85e-06187146777f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 GRIA1 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

3.06e-061891467a153b83314cf52808f685296cff8c95af3f4983d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 GRIA1 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

3.40e-061921467dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellLPS-IL1RA-Stromal_mesenchymal|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 FGF2 SORCS3 PLEKHH2

3.40e-0619214674e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2 VEGFA

3.40e-061921467ee085e04d5dcfb657522484ed20b8c1ddeccfe0c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 GRIA1 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

3.64e-06194146760622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 GRIA1 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

3.64e-06194146789b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEDD4L ANO1 IQGAP1 CLIC5 CCZ1 CD36 VEGFA

3.76e-06195146743164511f32e4591cb5399182fbac0b911716233
ToppCellPND01-Epithelial-Epithelial_Alveolar|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEDD4L ANO1 IQGAP1 CLIC5 CCZ1 CD36 VEGFA

3.76e-0619514679337111d75a487abc02969337718c30b1fe81379
ToppCellASK428-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

DOCK4 NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

4.16e-0619814670047a9ef7684230ac5179efea94461480e90bdaf
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CNTN4 COL6A5 LRP1 GLIPR2 SORCS3 PLEKHH2 VEGFA

4.30e-061991467ba586690f88fd051f449753bfe7603a2cb431782
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CNTN4 COL6A5 LRP1 GLIPR2 SORCS3 PLEKHH2 VEGFA

4.30e-06199146706a7d874ff7c4616577f6e59d3118717a8c47c00
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

LILRB2 CLU CD36 LRP1 GLIPR2 SCPEP1 VEGFA

4.30e-061991467cd93e8947bcf3c2d7e6d5bfd70300145fba15f74
ToppCellwk_08-11-Epithelial-Airway_epithelial_progenitor-epi-stalk_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CRLF1 NEDD4L PPP1R3B LAMA1 CLU PTPRZ1 TSPAN13

4.30e-061991467debdd7dba774d9ccff7effc3f4c132393d203dfa
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CNTN4 LAMA1 COL6A5 LRP1 SORCS3 PLEKHH2 VEGFA

4.30e-061991467a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

COL6A5 CLU LRP1 GLIPR2 SORCS3 PLEKHH2 VEGFA

4.30e-061991467211c3a08f2d484ab7a3368006767289088f0d957
ToppCellmLN-(5)_Dendritic_cell-(54)_pDC|mLN / shred on region, Cell_type, and subtype

HNF1A LILRB2 CSF2RB GUCA1A EPHA2 CD36 TSPAN13

4.30e-0619914671e738219784a446ee8b0ddeb408e0050e1929e60
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

COL6A5 CLU LRP1 GLIPR2 SORCS3 PLEKHH2 VEGFA

4.30e-0619914671a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellmLN-Dendritic_cell-pDC|mLN / Region, Cell class and subclass

HNF1A LILRB2 CSF2RB GUCA1A EPHA2 CD36 TSPAN13

4.30e-06199146754f1abb57af7bf8a8b82a38b933f257df3b5d8df
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 GRIA1 COL6A5 PTPRZ1 CD36 ROBO2 PLEKHH2

4.30e-061991467212e89d097753790061310373a1fafba773488b6
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 GRIA1 COL6A5 PTPRZ1 CD36 ROBO2 PLEKHH2

4.30e-06199146714b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell(54)_pDC|World / shred on Cell_type and subtype

HNF1A LILRB2 CSF2RB GUCA1A EPHA2 CD36 TSPAN13

4.90e-062031467b8ba3e51770ff7b45cd02472f3e63aa4d5816f6f
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GALC MYO9A DOCK10 IQGAP1 CSF2RB EBI3

1.33e-051571466ec433d2fe827abdb647be4176c231b7052482b6f
ToppCellLV-16._Neuronal|World / Chamber and Cluster_Paper

AKT3 BBS2 GRIA1 PTPRZ1 SORCS3 ARAP2

1.76e-0516514666ed52cb756d21addf46c7f6c457458b01339fe04
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

MYO9A SLC35G2 NEB MEMO1 CLU PHTF1

2.30e-05173146642c911ed16fabdabef063830e8407192d8bde950
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

DTL ANO1 GRIA1 CLU PTPRZ1 FGF2

2.38e-0517414669f2e253694eb5860c00528fda31c305c6de8a2a1
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HTR1E DOCK10 ANO1 FNDC1 ROBO2 SNTG2

2.62e-05177146684116796ca4c7007508c0f1a68a1135c7b922278
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNTN4 STXBP5L SLC35G2 SLCO5A1 CLIC5 PTPRZ1

2.79e-0517914667c8a2fa1326c73dc9e774df645b572864fd97133
ToppCellwk_20-22-Hematologic-Myeloid-aDC_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

SIGLEC12 LILRB2 TNIP2 SLCO5A1 EBI3 FERMT3

2.97e-0518114668f7e5c310f4cdc4b2fb54fea950d01e56bd298e1
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)|343B / Donor, Lineage, Cell class and subclass (all cells)

MYO1B FNDC1 CLIC5 NRK TSPAN13 VEGFA

3.25e-051841466cb15d6bae52c5ec251c2235859dc7e65f630ae23
ToppCell343B-Epithelial_cells-Epithelial-I_(AT1)-|343B / Donor, Lineage, Cell class and subclass (all cells)

MYO1B FNDC1 CLIC5 NRK TSPAN13 VEGFA

3.25e-051841466bde4eaabd3e9bdaed23867d23a919b9d84b52d4b
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1|Children_(3_yrs) / Lineage, Cell type, age group and donor

NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

3.35e-0518514661c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

CNTN4 NEDD4L MYO1B CLIC5 ARAP2 VEGFA

3.35e-05185146632b4e68e551d435a732f253f6ad83408c759a642
ToppCellEpithelial-alveolar_epithelial_cell_type_1|World / Lineage, Cell type, age group and donor

NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

3.46e-05186146609d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCellE17.5-Epithelial-alveolar_epithelial_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CRLF1 NEDD4L ANO1 IQGAP1 CLIC5 VEGFA

3.46e-051861466a7a2ef8392a045a62fa4d0983577711d5d397dc4
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 MYO9A PPP1R3B PKP4 LAMA1 NRK

3.46e-051861466f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DCDC1 MYO9A PPP1R3B PKP4 LAMA1 NRK

3.56e-051871466c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D175|Adult / Lineage, Cell type, age group and donor

GRIA1 COL6A5 RUNX1T1 FGF2 ROBO2 PLEKHH2

3.56e-051871466e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CNTN4 MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

3.56e-051871466d4b0afd9b92c47c8aa348bbd1af7eb54c3d478f2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

NEDD4L CLIC5 NRK TSPAN13 CATSPERB ARAP2

3.67e-05188146643a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCellMesenchymal-chondrocyte|World / Lineage, Cell type, age group and donor

FNDC1 CLU PTPRZ1 NRK FGF2 PLEKHH2

3.67e-0518814667b1e3f8a941eaa68e89c562129a92314642eec66
ToppCellrenal_medulla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

AKT3 NEDD4L MYO9A PKP4 LAMA1 PLEKHH2

3.78e-051891466830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

3.78e-0518914662a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D231|Adult / Lineage, Cell type, age group and donor

NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

3.78e-0518914665a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 NEDD4L MYO1B CLIC5 TSPAN13 VEGFA

3.89e-05190146630b50d183d7649146eb1e79b47ba897355f1998a
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage1_(2)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

LILRB2 RENBP EBI3 CD36 ARAP2 FERMT3

4.01e-051911466c383ae386bc53e73a683a9543c7dfed2a65257c5
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

4.01e-051911466b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellControl-Stromal_mesenchymal|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ANO1 COL6A5 FNDC1 LRP1 SORCS3 PLEKHH2

4.01e-05191146614057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

4.13e-0519214666f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CRLF1 LAMA1 PTPRZ1 EPHA2 TSPAN13 CATSPERB

4.13e-05192146639804d9ddc67c1b41887752df2503389eae44a1a
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 LRP1 FGF2 SORCS3 PLEKHH2

4.13e-051921466f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 VEGFA

4.13e-051921466df1545670370fb1010c567cd059c2783eab315f7
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

4.13e-051921466162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

4.13e-0519214663d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

4.13e-051921466deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEDD4L PPP1R3B ANO1 IQGAP1 CLIC5 VEGFA

4.25e-05193146654506c0da2f219f472b95e8935a78b657a8dec41
ToppCellURO|World / Disease, Lineage and Cell Type

SIGLEC12 LILRB2 EBI3 CLU CD36 LRP1

4.25e-051931466421dc0996c6c973f88e90197b651255ae4dd13a2
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-Sox9_Epi-Sox9_Epi_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRLF1 NEDD4L PPP1R3B ANO1 IQGAP1 CLU

4.25e-05193146633c495a2a7252b48ce10321642fd675d03cc80fc
ToppCellE18.5-Epithelial-Epithelial_Alveolar|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEDD4L PPP1R3B IQGAP1 CCZ1 CD36 VEGFA

4.25e-0519314668e750a2b198ad6840a6842a7ddd93623faf7c656
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

DOCK4 ANO1 GRIA1 RUNX1T1 ROBO2 PLEKHH2

4.25e-05193146699525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEDD4L PPP1R3B IQGAP1 CCZ1 CD36 VEGFA

4.25e-0519314666cc09f20dd119236c3c9968f3d16c3eabc0811e2
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

4.25e-051931466fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellE18.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEDD4L PPP1R3B ANO1 IQGAP1 CLIC5 VEGFA

4.25e-0519314662d42721fac1bee294ede47d609bebb3e7d36bf0c
ToppCellControl-Stromal-Myofibroblast|Stromal / Disease state, Lineage and Cell class

DOCK4 ANO1 GRIA1 COL6A5 ROBO2 PLEKHH2

4.25e-0519314665896242f713ae5fd1a4ebb63827f15d7279dced2
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK4 MAN1C1 GRIA1 RUNX1T1 ROBO2 PLEKHH2

4.37e-051941466011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

AKT3 PKP4 DTL CD36 ROBO2 CTNND1

4.37e-0519414660b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell368C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 GRIA1 COL6A5 CD36 ROBO2 PLEKHH2

4.37e-051941466d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CNTN4 COL6A5 RUNX1T1 LRP1 SORCS3 PLEKHH2

4.37e-0519414666e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellPND01-Epithelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NEDD4L ANO1 IQGAP1 CLIC5 CCZ1 VEGFA

4.37e-051941466d21db5e942966ed44bc78ff50130a201fc627074
ToppCell368C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

DOCK4 GRIA1 COL6A5 CD36 ROBO2 PLEKHH2

4.37e-051941466e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCellPCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CRLF1 CLIC5 NRK TSPAN13 CATSPERB ARAP2

4.50e-051951466d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCellE16.5-Epithelial-Epithelial_Alveolar|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRLF1 NEDD4L PPP1R3B ANO1 IQGAP1 CLU

4.63e-0519614661756254a61ea92601ed5e223ef4471f010c12216
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

MYO9A PKP4 NRK FGF2 SORCS3 PLEKHH2

4.63e-05196146604f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

4.63e-0519614666731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DOCK4 CLIC5 TSPAN13 FGF2 ANGPTL7 VEGFA

4.63e-0519614666c99d29162848161c1f166a032320f87a5d5a631
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NEDD4L MYO1B CLIC5 TSPAN13 ANGPTL7 VEGFA

4.63e-051961466eb68f7954e7c2f86d05e740e95b6e74805a6053f
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

4.63e-0519614666856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CRLF1 NEDD4L PPP1R3B ANO1 IQGAP1 CLU

4.63e-051961466caa3c9555e1c656e88246ed31388a818f77610a1
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

GRIA1 COL6A5 LRP1 SORCS3 PLEKHH2 VEGFA

4.76e-051971466fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK4 DOCK10 RUNX1T1 LRP1 ROBO2 PLEKHH2

4.76e-05197146631a1852911bda38543916585fda34255fd62a134
ToppCell15-Distal-Epithelial-Bud_tip_progenitor|Distal / Age, Tissue, Lineage and Cell class

CRLF1 PPP1R3B CLU PTPRZ1 CD36 TSPAN13

4.76e-051971466532635810f17199fa6c14b986f663884d5d05ab5
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

NEDD4L MYO1B CLIC5 TSPAN13 ARAP2 VEGFA

4.76e-0519714669ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCell(5)_Fibroblasts-(5)_Fibroblast-G|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

DOCK4 GRIA1 COL6A5 PTPRZ1 CD36 PLEKHH2

4.76e-051971466a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LILRB2 CLU CD36 LRP1 GLIPR2 SCPEP1

4.90e-051981466cf0fda1a24449cfd8ed56ffc7841d8accb187949
ToppCell(5)_Dendritic_cell-(54)_pDC|(5)_Dendritic_cell / shred on Cell_type and subtype

PPP1R3B CSF2RB GUCA1A EPHA2 TSPAN13 CDYL

4.90e-051981466fc6c6b60dddd7f2f997af0f87fae33f1c23f34a8
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

GRIA1 COL6A5 RUNX1T1 LRP1 ROBO2 PLEKHH2

4.90e-0519814663ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LILRB2 CLU CD36 LRP1 GLIPR2 SCPEP1

4.90e-0519814667e1f08dae11a7cc7949a5622d82c7e6660d06dea
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LILRB2 CLU CD36 LRP1 GLIPR2 SCPEP1

4.90e-051981466525adc91fd8f2ad957b1879a5bf3950baa7d5ef8
ToppCellFetal_29-31_weeks-Epithelial-club_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CNTN4 HTR1E NEDD4L TTPA CLU PTPRZ1

4.90e-0519814665fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LILRB2 CLU CD36 LRP1 GLIPR2 SCPEP1

4.90e-05198146670e62d815b2a0aa5327ff94d6f4d503176e007b9
Diseasemacular retinal edema (is_marker_for)

CLU FGF2 VEGFA

2.23e-05121403DOID:4449 (is_marker_for)
DiseaseCorneal Neovascularization

FGF2 VEGFA

2.24e-0521402C0085109
DiseaseArthrogryposis

ERCC6 MYO9A DYNC1H1

1.31e-04211403C0003886
DiseaseThoracic Diseases

ATRX IFT80

1.33e-0441402C0039978
Diseasedecubitus ulcer (biomarker_via_orthology)

FGF2 VEGFA

1.33e-0441402DOID:8717 (biomarker_via_orthology)
Diseasethyroxine-binding globulin measurement

HNF1A NRK

2.21e-0451402EFO_0009172
Diseasepolyarteritis nodosa (is_marker_for)

FGF2 VEGFA

2.21e-0451402DOID:9810 (is_marker_for)
Diseasepre-eclampsia (is_implicated_in)

HNF1A CLU VEGFA

2.23e-04251403DOID:10591 (is_implicated_in)
DiseasePathologic Neovascularization

CLU VEGFA

3.31e-0461402C0027686
DiseaseSevere Congenital Microcephaly

ERCC6 PLK4 DYNC1H1

4.26e-04311403C3853041
Diseaseresponse to 5-fluorouracil, response to antineoplastic agent

MYO1B ARAP2

4.62e-0471402GO_0036275, GO_0097327
DiseaseMicrolissencephaly

ERCC6 PLK4 DYNC1H1

5.14e-04331403C1956147
Diseasemelanoma (is_marker_for)

ATRX BRD2 VEGFA

5.14e-04331403DOID:1909 (is_marker_for)
Diseaseretinal vein occlusion (biomarker_via_orthology)

FGF2 VEGFA

6.14e-0481402DOID:1727 (biomarker_via_orthology)
DiseaseGrowth Disorders

CNTN4 ERCC6 ATRX

6.66e-04361403C0018273
Diseasepterygium (is_marker_for)

FGF2 VEGFA

7.87e-0491402DOID:0002116 (is_marker_for)
Diseasemiddle cerebral artery infarction (biomarker_via_orthology)

ERCC6 PTPRZ1 FGF2 VEGFA

1.02e-03931404DOID:3525 (biomarker_via_orthology)
Diseaseacute insulin response measurement

HNF1A ARAP1

1.20e-03111402EFO_0006831
DiseaseGastric Adenocarcinoma

MINK1 BRD2 EPHA2

1.28e-03451403C0278701
Diseasesusceptibility to childhood ear infection measurement

ANO1 ELP1 BRD2 MKX USP4

1.37e-031711405EFO_0007904
Diseaseserum gamma-glutamyl transferase measurement

SEC16B HNF1A NEDD4L ATRX MYO9A MYO1B BHMT EPHA2 IFT80 ANAPC5 ARAP2 VEGFA

1.41e-0391414012EFO_0004532
DiseaseWeight Gain

SLU7 MYO1B IQGAP1 CD36

1.44e-031021404C0043094
DiseaseRetinitis Pigmentosa

CCZ1B BBS2 PRPF8 TTPA

1.55e-031041404C0035334
Diseaseschizophrenia, anorexia nervosa

CNTN4 AKT3 ACTR5

1.55e-03481403MONDO_0005090, MONDO_0005351
Diseaseattention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement

AKT3 NRAP DCDC1 MINK1 DOCK10 ELP1 RUNX1T1 PHF20L1 SORCS3 ROBO2 ARAP2

1.57e-0380114011EFO_0003888, EFO_0007052, MONDO_0002491
Diseasealcohol and nicotine codependence

RGPD2 RGPD1

1.68e-03131402EFO_0004776
Diseasediabetic retinopathy (is_implicated_in)

CLU FGF2 VEGFA

1.74e-03501403DOID:8947 (is_implicated_in)
DiseaseInfluenza

DDX60 IFIT5 ZCCHC2

1.95e-03521403C0021400
DiseaseMalformations of Cortical Development

AKT3 DYNC1H1

1.96e-03141402C1955869
DiseaseCortical Dysplasia

AKT3 DYNC1H1

1.96e-03141402C0431380
Diseasediabetic neuropathy (is_implicated_in)

FGF2 VEGFA

1.96e-03141402DOID:9743 (is_implicated_in)
DiseaseHermansky-Pudlak syndrome (implicated_via_orthology)

CCZ1B CCZ1

1.96e-03141402DOID:3753 (implicated_via_orthology)
DiseaseGlioblastoma Multiforme

AKT3 ATRX BRD2 VEGFA

1.96e-031111404C1621958
Diseasebasophil count

CNTN4 GALC ANO1 COL6A5 IQGAP1 SLCO5A1 CSF2RB CD36

2.21e-034831408EFO_0005090
Diseaseglucose measurement

HNF1A ELP1 CRY2 IFT80 PLEKHH2 ARAP1 VEGFA

2.31e-033801407EFO_0004468
Diseasecholesteatoma of middle ear (is_marker_for)

FGF2 VEGFA

2.57e-03161402DOID:10964 (is_marker_for)
Diseasewhite matter microstructure measurement

UTP6 AKT3 DCDC1 AXDND1 WDR75 ROBO2 CATSPERB

2.67e-033901407EFO_0005674
Diseasecyclic adenosine monophosphate measurement

CD36 ARAP2

2.90e-03171402EFO_0010473
Diseasenon-Hodgkin lymphoma (is_implicated_in)

TMEM260 RAD54L

2.90e-03171402DOID:0060060 (is_implicated_in)
DiseaseLiver Cirrhosis, Experimental

GALC PPP1R3B DOCK10 IQGAP1 CD36 FGF2 ROBO2 ALDH1B1 GOT1 VEGFA

3.93e-0377414010C0023893
DiseaseMicrocephaly

ERCC6 PLK4 DYNC1H1

4.01e-03671403C0025958
Diseasecoronary artery disease (is_marker_for)

CLU FGF2 VEGFA

4.01e-03671403DOID:3393 (is_marker_for)
Diseaseprostate adenocarcinoma (is_implicated_in)

AKT3 FGF2

4.02e-03201402DOID:2526 (is_implicated_in)
DiseaseAbdominal Aortic Aneurysm

PKP4 LRP1 ALDH1B1

4.18e-03681403EFO_0004214
DiseaseAntimigraine preparation use measurement

RUNX1T1 LRP1

4.42e-03211402EFO_0009939
DiseaseLymphoma, Diffuse

BHMT RAD54L

4.42e-03211402C3714542
DiseaseLow Grade Lymphoma (neoplasm)

BHMT RAD54L

4.42e-03211402C0079747
DiseaseLymphoma, Intermediate-Grade

BHMT RAD54L

4.42e-03211402C0079741
DiseaseHigh Grade Lymphoma (neoplasm)

BHMT RAD54L

4.42e-03211402C0079740
DiseaseDiffuse Mixed-Cell Lymphoma

BHMT RAD54L

4.42e-03211402C0079757
DiseaseLymphoma, Undifferentiated

BHMT RAD54L

4.42e-03211402C0024306
DiseaseReticulosarcoma

BHMT RAD54L

4.42e-03211402C0024302
DiseaseLymphoma, Mixed-Cell

BHMT RAD54L

4.42e-03211402C0024304

Protein segments in the cluster

PeptideGeneStartEntry
LWQYRDLRSIYKKDG

PKP4

991

Q99569
ATRWDIQKYAREAYN

BHMT

276

Q93088
TSKVRRWENYYLGKF

C21orf140

236

B9A014
INEKGSDRYRNAYVW

EDDM3A

81

Q14507
KREVQLRLSYVYDWS

B3GALT6

301

Q96L58
KYGDAWVKKYDRSSL

ACSS1

396

Q9NUB1
AYELVTGRRLWKNVY

ARID5A

101

Q03989
AIEVNKRDYRAWYGL

CDC23

391

Q9UJX2
FERVDYVKGKLWYNE

CATSPERB

286

Q9H7T0
RKRGKRRYFWEYSEQ

CREBRF

426

Q8IUR6
EVIKVYRYFAGWADK

ALDH1B1

141

P30837
YWAITNAIEYARKRT

HTR1E

121

P28566
SEVKGYKVLYRWNRQ

CNTN4

931

Q8IWV2
YREAIIKYQGLEWKS

ABCB6

476

Q9NP58
YKKRLEDQGVRVTWY

AADACL4

356

Q5VUY2
SLSGYQYTRRAWKKE

DOP1A

2096

Q5JWR5
QKRWVKFDGLSISYY

ARAP2

501

Q8WZ64
WITRKEYEEKGGEYL

ACTR5

551

Q9H9F9
KVWDLRKNYTAYRQE

DTL

241

Q9NZJ0
TGLWRYLKNAYARDE

CLIC5

371

Q9NZA1
GDEDYYKQRLRRWNK

ERCC6

456

Q03468
GEYIKNWRPRYFLLK

AKT3

16

Q9Y243
WRGYKQKKAYQDRLA

IQGAP1

786

P46940
RAKLYRYDKDVGQWK

RANBP2

2336

P49792
YREKYDWRRGRSKSR

RBM27

156

Q9P2N5
RVWRDGQKKTCYIYR

RAD54L

606

Q92698
AEIYRYDKDVGQWKE

RGPD5

1361

Q99666
AEIYRYDKDVGQWKE

RGPD8

1361

O14715
RRKSGLVSFYRDWKQ

ANGPTL7

176

O43827
WLYVLGQKRSDSYVL

ANAPC5

346

Q9UJX4
GRVYDDLKYVWLQGR

RENBP

56

P51606
NEQKIWVSYGRAYRS

DCDC1

571

M0R2J8
NAELERKIKGWYEKY

KRT28

111

Q7Z3Y7
IALDYKREAKGELYW

MGAM2

791

Q2M2H8
RYKESWRNLRAQGYK

NRAP

1271

Q86VF7
YWIRRYSDAEDLKKG

RUNX1T1

391

Q06455
GWKARKNYRKYFRSE

MYO1A

756

Q9UBC5
FLYRREKAAGEKVYW

FLYWCH1

436

Q4VC44
LYWTDVVEDKIYRGK

LRP1

1311

Q07954
YQNGAERRWEKSSRY

CWC22

871

Q9HCG8
KDYEYLWNTVSKLVR

DDX60

406

Q8IY21
DLSWALRIKLYNKYV

MKX

136

Q8IYA7
ESAVWYVKKFGRYLE

FBXO39

76

Q8N4B4
QEYRLYREKKSASWI

LILRB2

56

Q8N423
TQKRAALYTWYVRKQ

HNF1A

156

P20823
GAAWEEALRLVYKYN

ELP1

1086

O95163
NDRKLLYEEWARYGV

ANO1

296

Q5XXA6
YRQQRKLVEEIGWSY

PTPRZ1

26

P23471
KRRWFVLKGGELLYY

PLEKHH2

721

Q8IVE3
LKKLLERIGYSNEWY

OR5AS1

301

Q8N127
RAEFYRYDKDVGQWK

RGPD3

1361

A6NKT7
YKGEGKWLRNIDYYR

ATRX

2071

P46100
KWLRNIDYYRLDGST

ATRX

2076

P46100
YGYRLRRKWEEKIPN

CSF2RB

466

P32927
YNWERALELAVKYKT

IFT80

696

Q9P2H3
VLRYAAKFYRRKNSW

IFIT5

251

Q13325
VGVYDKTSRYWRIKS

BBS2

226

Q9BXC9
EWLRIGNKYITLKDY

C5orf60

81

A6NFR6
IAALIAEYLKRKGYW

DOCK10

1726

Q96BY6
GALAYRDLIKVLKWY

DOCK4

671

Q8N1I0
KTEYLVRWKGYDSED

CDYL

76

Q9Y232
YRLWDLYKKVKRNST

CRY2

286

Q49AN0
GKEVADRWYSEIKNY

GLIPR2

76

Q9H4G4
IIDTYKGKRNLSYWE

CD36

226

P16671
QYTVRYREKGELARW

FNDC1

296

Q4ZHG4
YREKGELARWDYKQI

FNDC1

301

Q4ZHG4
DKASYEIKKVWYGRT

DIS3L

566

Q8TF46
VWKYEVTYRKKGDSN

EPHA2

466

P29317
RRLYLNEKGWNKYTK

AXDND1

421

Q5T1B0
SYLIRWSDYNRKKQL

COL6A5

1811

A8TX70
KVADWTGATYQDKRY

EIF3D

41

O15371
NEIASVAYRYRRWKL

EIF3D

351

O15371
VAYRYRRWKLGDDID

EIF3D

356

O15371
DYWVVGKKSDRRELY

CCZ1

436

P86791
FSLKYWIRYKRQGAA

EBI3

161

Q14213
DYWVVGKKSDRRELY

CCZ1B

436

P86790
IRSYRYWDAEKRGLD

GOT1

156

P17174
IGWRREGNEIKYYKN

AGBL2

351

Q5U5Z8
GKVEQKLRWYFKLYD

GUCA1A

86

P43080
DNRIGGKYWKVRYTE

HEPHL1

421

Q6MZM0
WQSYKRYAMGKNELR

MAN1C1

186

Q9NR34
GDWKSYQYLVESIRR

COQ5

276

Q5HYK3
QERLRYAPLGWSKKY

DYNC1H1

4191

Q14204
RKYTSWYVALKRTGQ

FGF2

251

P09038
KWQKFVYIYDADRGL

GRIA1

141

P42261
KYQIRYRVEDSVDWK

CRLF1

271

O75462
IYALGRVEVTAKKWY

GALC

616

P54803
IDYGFWYDRTKQTIK

DNAH2

2506

Q9P225
WTYGRYIRSALRQEK

CTNND1

696

O60716
YWDSNRGKNYRIIRA

PPP1R3B

221

Q86XI6
AELYRYDKDVGQWKE

RGPD1

1346

P0DJD0
LIIQNWYRGYKARLK

PPEF1

21

O14829
AKYRYDKEWLNNGRM

PHF20L1

736

A8MW92
DKYRASIRGKKWYSS

PGBD3

471

Q8N328
YDLRIDQKIYGELWK

MEMO1

101

Q9Y316
SGKRNKLRVYYLSWL

MINK1

1076

Q8N4C8
RVNKYQKSVGWRYSD

NRK

71

Q7Z2Y5
LDWAYRSGGYKKARA

UTP6

481

Q9NYH9
RAELYRYDKDVGQWK

RGPD4

1361

Q7Z3J3
FWKATRSYLQYRGKK

RGSL1

981

A5PLK6
KWKENGYYRAIVTKL

TDRD6

546

O60522
KMYSREWNRDVQYRG

SRP19

66

P09132
SREKTSDIYIKGWLY

FER1L5

1741

A0AVI2
LYRYDKDVGQWKERG

RGPD2

1356

P0DJD1
QVKTYITYNKGRDWR

SORCS3

511

Q9UPU3
GKEVWDYVTVRKDAY

SCPEP1

36

Q9HB40
FVLAGYKLYWRNLRK

SLC35G2

386

Q8TBE7
IRKEYWRYIGRSLQS

FNTA

351

P49354
LLTDRRYNNGTWYKI

LAMA1

2376

P25391
AWYSIKYKEDGLQRR

SLCO5A1

756

Q9H2Y9
IWREQYEKAYLKSLD

SIN3B

591

O75182
YSGYRFILTAWEKKL

SIRT4

266

Q9Y6E7
RYKAGTEKLRWNAFE

SNTG2

231

Q9NY99
SRYSFDNLPEKYWRK

PLK4

671

O00444
YRRVKRLYSNWRKGE

SUPT16H

11

Q9Y5B9
ERGSRKWNYIYDKLS

SIGLEC12

251

Q96PQ1
WDLKSKRAELRVYYD

STXBP5L

236

Q9Y2K9
WYTKYASRLAGKENI

BROX

121

Q5VW32
IKRRLENNYYWAASE

BRD2

126

P25440
GSYIYQKRWVRLDTD

ARAP1

341

Q96P48
RLTRKYNELLKSYQW

CLU

336

P10909
GVQRKRADKYWEYTF

ZCCHC2

361

Q9C0B9
AYDKGWRVRTDFKQY

PRPF8

1431

Q6P2Q9
ENKKEYVRLYVNWRF

SMURF2

576

Q9HAU4
KWQRYNASRDEYVRG

TNIP2

226

Q8NFZ5
SLKSRGYVKEQFAWR

RPS10

51

P46783
REKYNRIAREWTQKY

UBE2D2

131

P62837
LVKRQSRDYDVEWGY

UNC50

141

Q53HI1
KRFSYNRYWRDKLDT

USP4

826

Q13107
ILGVWLTYRYRNQKD

TSPAN13

181

O95857
KARQWKYDGEMLNRY

TEP1

641

Q99973
RDAISWYQKKIGAYD

PHTF1

6

Q9UMS5
KIRLWRNFYDDKKYT

WDR75

226

Q8IWA0
GNKAYRTWYAKLDEE

PTPA

136

Q15257
RDKYNRISREWTQKY

UBE2D3

131

P61077
WYKRGVKENSIITKY

SLU7

101

O95391
YWRRKKRKGLSNYAV

ROBO2

881

Q9HCK4
IKAGDALWLRFKYYS

FERMT3

241

Q86UX7
FDLDLAWRLLKNYYK

TTPA

61

P49638
FQKYLREYAWKILSG

VPS53

501

Q5VIR6
TRLLYYGRKKEALEW

SEC16B

446

Q96JE7
VYYRLAKENGWRARS

FTSJ1

11

Q9UET6
EENLKSYRKLLLWGY

ZSCAN18

236

Q8TBC5
REKYNRLAREWTQKY

UBE2D4

131

Q9Y2X8
KKSRYKSWSVYVGAR

VEGFA

156

P15692
KLTKSIYNWTEEYGR

TMEM260

561

Q9NX78
QEKIIRGYEAKWIYI

LRRIQ3

246

A6PVS8
AYWLGLKVRREYRKF

MYO1B

846

O43795
CIQARWKAYRESKRY

MYO9A

1121

B2RTY4
WKAYRESKRYQEQRK

MYO9A

1126

B2RTY4
YKRDWYDLIAKGNNV

NEB

1296

P20929
ARILDQYLYKEGWER

NEB

4206

P20929
WEERKDAKGRTYYVN

NEDD4L

391

Q96PU5