Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-L-arabinofuranosidase activity	OTOGL OTOG	3.34e-06	2	37	2	GO:0046556
GeneOntologyMolecularFunction	acyltransferase activity	ZDHHC5 TRIM64B TRAF2 TRIM64 ZDHHC8 TRIM64C MARCHF9	4.80e-04	775	37	7	GO:0016746
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC5 ZDHHC8	1.06e-03	26	37	2	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC5 ZDHHC8	1.06e-03	26	37	2	GO:0019707
GeneOntologyMolecularFunction	S-acyltransferase activity	ZDHHC5 ZDHHC8	1.41e-03	30	37	2	GO:0016417
GeneOntologyMolecularFunction	ubiquitin-protein transferase activity	TRIM64B TRAF2 TRIM64 TRIM64C MARCHF9	1.70e-03	473	37	5	GO:0004842
GeneOntologyMolecularFunction	palmitoyltransferase activity	ZDHHC5 ZDHHC8	2.14e-03	37	37	2	GO:0016409
GeneOntologyMolecularFunction	ubiquitin-like protein transferase activity	TRIM64B TRAF2 TRIM64 TRIM64C MARCHF9	2.41e-03	512	37	5	GO:0019787
GeneOntologyMolecularFunction	aminoacyltransferase activity	TRIM64B TRAF2 TRIM64 TRIM64C MARCHF9	2.84e-03	532	37	5	GO:0016755
GeneOntologyMolecularFunction	protein kinase binding	TRIM64B NELL2 TRAF2 TRIM64 FBXO5 TRIM64C	5.00e-03	873	37	6	GO:0019901
GeneOntologyMolecularFunction	zinc ion binding	TRIM64B TRAF2 TRIM64 TRIM64C PLSCR1 MARCHF9	5.52e-03	891	37	6	GO:0008270
GeneOntologyBiologicalProcess	arabinose metabolic process	OTOGL OTOG	2.80e-06	2	35	2	GO:0019566
GeneOntologyBiologicalProcess	vibrational conductance of sound to the inner ear	OTOGL OTOG	2.80e-06	2	35	2	GO:0055127
GeneOntologyBiologicalProcess	L-arabinose metabolic process	OTOGL OTOG	2.80e-06	2	35	2	GO:0046373
GeneOntologyBiologicalProcess	protein ubiquitination	TRIM64B FBXO38 TRAF2 TRIM64 FBXO5 MEGF8 TRIM64C MARCHF9	5.05e-05	811	35	8	GO:0016567
GeneOntologyBiologicalProcess	protein modification by small protein conjugation	TRIM64B FBXO38 TRAF2 TRIM64 FBXO5 MEGF8 TRIM64C MARCHF9	9.93e-05	893	35	8	GO:0032446
GeneOntologyBiologicalProcess	negative regulation of glial cell apoptotic process	TRAF2 DLL1	1.52e-04	11	35	2	GO:0034351
GeneOntologyBiologicalProcess	pentose metabolic process	OTOGL OTOG	2.16e-04	13	35	2	GO:0019321
GeneOntologyBiologicalProcess	protein modification by small protein conjugation or removal	TRIM64B FBXO38 TRAF2 TRIM64 FBXO5 MEGF8 TRIM64C MARCHF9	2.30e-04	1009	35	8	GO:0070647
GeneOntologyBiologicalProcess	regulation of glial cell apoptotic process	TRAF2 DLL1	3.31e-04	16	35	2	GO:0034350
GeneOntologyBiologicalProcess	post-translational protein modification	TRIM64B FBXO38 TRAF2 TRIM64 FBXO5 MEGF8 TRIM64C MARCHF9	3.52e-04	1074	35	8	GO:0043687
GeneOntologyCellularComponent	keratin filament	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	2.09e-08	97	38	6	GO:0045095
GeneOntologyCellularComponent	intermediate filament	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	3.17e-06	227	38	6	GO:0005882
GeneOntologyCellularComponent	intermediate filament cytoskeleton	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	7.38e-06	263	38	6	GO:0045111
Domain	Keratin_B2_2	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	1.03e-10	39	36	6	PF13885
Domain	Keratin_B2	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	1.21e-10	40	36	6	PF01500
Domain	KAP	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	1.25e-09	58	36	6	IPR002494
Domain	EGF_3	ASTN2 NELL2 DLL1 MEGF8 OTOG	8.29e-05	235	36	5	PS50026
Domain	EGF_1	ASTN2 NELL2 DLL1 MEGF8 ITGB8	1.22e-04	255	36	5	PS00022
Domain	PSI_integrin	MEGF8 ITGB8	1.29e-04	9	36	2	PF17205
Domain	Integin_beta_N	MEGF8 ITGB8	1.29e-04	9	36	2	IPR033760
Domain	EGF_2	ASTN2 NELL2 DLL1 MEGF8 ITGB8	1.46e-04	265	36	5	PS01186
Domain	Growth_fac_rcpt_	NELL2 HTRA4 DLL1 MEGF8	2.24e-04	156	36	4	IPR009030
Domain	Znf_C3HC4_RING-type	TRIM64B TRAF2 TRIM64 MARCHF9	3.25e-04	172	36	4	IPR018957
Domain	VWC_out	NELL2 OTOG	6.05e-04	19	36	2	SM00215
Domain	EGF_Ca-bd_CS	NELL2 DLL1 MEGF8	8.56e-04	97	36	3	IPR018097
Domain	zf-C3HC4	TRIM64B TRAF2 TRIM64 MARCHF9	8.63e-04	223	36	4	PF00097
Domain	zf-DHHC	ZDHHC5 ZDHHC8	8.91e-04	23	36	2	PF01529
Domain	EGF_CA	NELL2 DLL1 MEGF8	9.08e-04	99	36	3	PS01187
Domain	ASX_HYDROXYL	NELL2 DLL1 MEGF8	9.35e-04	100	36	3	PS00010
Domain	EGF	NELL2 DLL1 MEGF8 ITGB8	1.05e-03	235	36	4	SM00181
Domain	DHHC	ZDHHC5 ZDHHC8	1.05e-03	25	36	2	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC5 ZDHHC8	1.05e-03	25	36	2	IPR001594
Domain	EGF-type_Asp/Asn_hydroxyl_site	NELL2 DLL1 MEGF8	1.11e-03	106	36	3	IPR000152
Domain	EGF-like_dom	NELL2 DLL1 MEGF8 OTOG	1.30e-03	249	36	4	IPR000742
Domain	EGF-like_CS	NELL2 DLL1 MEGF8 ITGB8	1.54e-03	261	36	4	IPR013032
Domain	EGF_CA	NELL2 DLL1 MEGF8	1.66e-03	122	36	3	SM00179
Domain	EGF-like_Ca-bd_dom	NELL2 DLL1 MEGF8	1.74e-03	124	36	3	IPR001881
Domain	Kazal_2	HTRA4 SLCO2A1	2.18e-03	36	36	2	PF07648
Domain	VWF_dom	NELL2 OTOG	2.96e-03	42	36	2	IPR001007
Domain	PSI	MEGF8 ITGB8	3.25e-03	44	36	2	IPR016201
Domain	Znf_RING	TRIM64B TRAF2 TRIM64 MARCHF9	3.46e-03	326	36	4	IPR001841
Domain	PSI	MEGF8 ITGB8	3.54e-03	46	36	2	SM00423
Domain	KAZAL	HTRA4 SLCO2A1	3.54e-03	46	36	2	SM00280
Domain	Znf_RING_CS	TRIM64B TRAF2 TRIM64	3.77e-03	163	36	3	IPR017907
Domain	KAZAL_2	HTRA4 SLCO2A1	4.18e-03	50	36	2	PS51465
Domain	Kazal_dom	HTRA4 SLCO2A1	4.34e-03	51	36	2	IPR002350
Domain	EGF_extracell	NELL2 ITGB8	5.96e-03	60	36	2	IPR013111
Domain	EGF_2	NELL2 ITGB8	5.96e-03	60	36	2	PF07974
Domain	F-box	FBXO38 FBXO5	7.38e-03	67	36	2	PF00646
Domain	BBOX	TRIM64B TRIM64	7.81e-03	69	36	2	SM00336
Domain	Butyrophylin	TRIM64B TRIM64	8.03e-03	70	36	2	IPR003879
Domain	-	TRIM64B TRIM64	8.26e-03	71	36	2	4.10.45.10
Domain	zf-B_box	TRIM64B TRIM64	8.48e-03	72	36	2	PF00643
Domain	FBOX	FBXO38 FBXO5	8.48e-03	72	36	2	PS50181
Domain	ConA-like_dom	TRIM64B NELL2 TRIM64	8.54e-03	219	36	3	IPR013320
Domain	-	ANTXRL ITGB8	8.94e-03	74	36	2	3.40.50.410
Domain	F-box_dom	FBXO38 FBXO5	9.18e-03	75	36	2	IPR001810
Domain	ZF_BBOX	TRIM64B TRIM64	1.04e-02	80	36	2	PS50119
Domain	-	TRIM64B TRAF2 TRIM64 MARCHF9	1.06e-02	449	36	4	3.30.40.10
Domain	Znf_B-box	TRIM64B TRIM64	1.06e-02	81	36	2	IPR000315
Domain	VWFA	ANTXRL ITGB8	1.09e-02	82	36	2	PS50234
Domain	Znf_RING/FYVE/PHD	TRIM64B TRAF2 TRIM64 MARCHF9	1.14e-02	459	36	4	IPR013083
Domain	VWA	ANTXRL ITGB8	1.14e-02	84	36	2	SM00327
Domain	EGF_CA	NELL2 MEGF8	1.19e-02	86	36	2	PF07645
Domain	SPRY	TRIM64B TRIM64	1.22e-02	87	36	2	SM00449
Domain	SPRY	TRIM64B TRIM64	1.41e-02	94	36	2	PF00622
Domain	SPRY_dom	TRIM64B TRIM64	1.41e-02	94	36	2	IPR003877
Domain	B30.2/SPRY	TRIM64B TRIM64	1.44e-02	95	36	2	IPR001870
Domain	B302_SPRY	TRIM64B TRIM64	1.44e-02	95	36	2	PS50188
Domain	LRRNT	PODNL1 CHADL	1.53e-02	98	36	2	IPR000372
Domain	LRRNT	PODNL1 CHADL	1.53e-02	98	36	2	SM00013
Pathway	REACTOME_KERATINIZATION	KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	5.08e-06	153	24	5	MM15343
Pathway	REACTOME_KERATINIZATION	KRTAP4-4 KRTAP4-5 KRTAP4-3 KRTAP10-10 KRTAP10-11	2.76e-05	217	24	5	M27640
Pubmed	Molecular evolution of the keratin associated protein gene family in mammals, role in the evolution of mammalian hair.	KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	1.27e-08	69	38	5	18721477
Pubmed	Size polymorphisms in the human ultrahigh sulfur hair keratin-associated protein 4, KAP4, gene family.	KRTAP4-4 KRTAP4-5 KRTAP4-3	6.71e-08	8	38	3	15955084
Pubmed	Characterization of a cluster of human high/ultrahigh sulfur keratin-associated protein genes embedded in the type I keratin gene domain on chromosome 17q12-21.	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3	7.79e-08	37	38	4	11279113
Pubmed	Trim43a, Trim43b, and Trim43c: Novel mouse genes expressed specifically in mouse preimplantation embryos.	TRIM64B TRIM64 TRIM64C	5.43e-07	15	38	3	19703589
Pubmed	Similar phenotypes caused by mutations in OTOG and OTOGL.	OTOGL OTOG	1.16e-06	2	38	2	24378291
Pubmed	Ankyrin-G palmitoylation and βII-spectrin binding to phosphoinositide lipids drive lateral membrane assembly.	ZDHHC5 ZDHHC8	1.16e-06	2	38	2	25049274
Pubmed	Palmitoylation by DHHC5/8 targets GRIP1 to dendritic endosomes to regulate AMPA-R trafficking.	ZDHHC5 ZDHHC8	3.48e-06	3	38	2	22325201
Pubmed	Proteome scale characterization of human S-acylated proteins in lipid raft-enriched and non-raft membranes.	ZDHHC5 ZDHHC8	3.48e-06	3	38	2	19801377
Pubmed	Assessment of community efforts to advance network-based prediction of protein-protein interactions.	KRTAP4-4 ZNF775 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11 RIC3	4.80e-06	630	38	7	36949045
Pubmed	Glucocorticoid-induced TNF receptor, a costimulatory receptor on naive and activated T cells, uses TNF receptor-associated factor 2 in a novel fashion as an inhibitor of NF-kappa B activation.	TNFRSF18 TRAF2	6.96e-06	4	38	2	15944293
Pubmed	Identification of a novel activation-inducible protein of the tumor necrosis factor receptor superfamily and its ligand.	TNFRSF18 TRAF2	1.16e-05	5	38	2	10037686
Pubmed	Lineage-specific biology revealed by a finished genome assembly of the mouse.	TRIM64B TRIM64 TRIM64C	3.04e-05	55	38	3	19468303
Pubmed	Protein interactions of the transcription factor Hoxa1.	TRAF2 KRTAP4-12 PLSCR1	4.35e-05	62	38	3	23088713
Pubmed	Hair greying is associated with active hair growth.	KRTAP4-5 KRTAP4-3	5.20e-05	10	38	2	21916889
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	OTOGL OTOG	6.35e-05	11	38	2	31776257
Pubmed	Identification of mechanosensitive genes during skeletal development: alteration of genes associated with cytoskeletal rearrangement and cell signalling pathways.	DLL1 VEGFD	7.62e-05	12	38	2	24443808
Pubmed	Human chromosome 11 DNA sequence and analysis including novel gene identification.	TRIM64B TRIM64 TRIM64C	9.33e-05	80	38	3	16554811
Pubmed	A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.	KRTAP10-10 KRTAP10-11	1.38e-04	16	38	2	15028290
Pubmed	Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.	ZDHHC5 ZDHHC8	1.38e-04	16	38	2	23034182
Pubmed	Identification of a genomic reservoir for new TRIM genes in primate genomes.	TRIM64B TRIM64	1.96e-04	19	38	2	22144910
Pubmed	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.	ZDHHC5 ZDHHC8	2.18e-04	20	38	2	16647879
Pubmed	Comparison of an expanded ataxia interactome with patient medical records reveals a relationship between macular degeneration and ataxia.	NELL2 TRAF2 MEGF8	2.95e-04	118	38	3	21078624
Pubmed	Protein interactome reveals converging molecular pathways among autism disorders.	NELL2 TRAF2 MEGF8 PLSCR1 RIC3	3.44e-04	560	38	5	21653829
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	NELL2 TRAF2 MEGF8 KRTAP4-12 PLSCR1	5.00e-04	608	38	5	16713569
Pubmed	FBXO38 Ubiquitin Ligase Controls Centromere Integrity via ZXDA/B Stability.	FBXO38 FBXO5	5.65e-04	32	38	2	35813202
Interaction	LCE3C interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-10 KRTAP10-11	1.11e-09	67	33	6	int:LCE3C
Interaction	HOXA1 interactions	KRTAP4-4 NELL2 TRAF2 MEGF8 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-10 KRTAP10-11	4.02e-09	356	33	9	int:HOXA1
Interaction	KRTAP5-6 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-10 KRTAP10-11	8.77e-09	94	33	6	int:KRTAP5-6
Interaction	LCE3B interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	1.12e-08	46	33	5	int:LCE3B
Interaction	CATSPER1 interactions	KRTAP4-4 TRAF2 KRTAP4-12 PLSCR1 KRTAP10-10 KRTAP10-11	5.11e-08	126	33	6	int:CATSPER1
Interaction	LCE1E interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	8.31e-08	68	33	5	int:LCE1E
Interaction	KRTAP5-7 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	1.03e-07	71	33	5	int:KRTAP5-7
Interaction	LCE2D interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-11	1.27e-07	74	33	5	int:LCE2D
Interaction	LCE1C interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	1.56e-07	77	33	5	int:LCE1C
Interaction	SMCP interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-11	1.77e-07	79	33	5	int:SMCP
Interaction	LCE4A interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-11	1.89e-07	80	33	5	int:LCE4A
Interaction	KRTAP4-4 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	2.01e-07	81	33	5	int:KRTAP4-4
Interaction	CREB5 interactions	KRTAP4-4 TRAF2 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	2.45e-07	164	33	6	int:CREB5
Interaction	LCE1B interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	2.56e-07	85	33	5	int:LCE1B
Interaction	LCE1F interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	3.81e-07	92	33	5	int:LCE1F
Interaction	KRTAP4-2 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-11	2.29e-06	132	33	5	int:KRTAP4-2
Interaction	KRTAP10-9 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 PGAP2 KRTAP10-11	2.32e-06	241	33	6	int:KRTAP10-9
Interaction	LCE3E interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	2.72e-06	60	33	4	int:LCE3E
Interaction	KRTAP9-3 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	3.06e-06	140	33	5	int:KRTAP9-3
Interaction	KRTAP10-11 interactions	KRTAP4-4 KRTAP4-12 PLSCR1 KRTAP10-11	3.53e-06	64	33	4	int:KRTAP10-11
Interaction	CRCT1 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	4.00e-06	66	33	4	int:CRCT1
Interaction	KRTAP9-2 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-11	4.15e-06	149	33	5	int:KRTAP9-2
Interaction	LCE2A interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	4.78e-06	69	33	4	int:LCE2A
Interaction	LCE1D interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	5.06e-06	70	33	4	int:LCE1D
Interaction	LCE3D interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	5.99e-06	73	33	4	int:LCE3D
Interaction	LCE3A interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	7.03e-06	76	33	4	int:LCE3A
Interaction	LCE2B interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	9.07e-06	81	33	4	int:LCE2B
Interaction	POU4F2 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	9.99e-06	83	33	4	int:POU4F2
Interaction	LCE1A interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	1.05e-05	84	33	4	int:LCE1A
Interaction	LCE2C interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10	1.26e-05	88	33	4	int:LCE2C
Interaction	LCE5A interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	1.38e-05	90	33	4	int:LCE5A
Interaction	GLRX3 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-11	1.39e-05	191	33	5	int:GLRX3
Interaction	CYSRT1 interactions	KRTAP4-4 ZNF775 KRTAP4-5 KRTAP4-12 KRTAP10-10 PGAP2 KRTAP10-11	1.56e-05	511	33	7	int:CYSRT1
Interaction	KRTAP5-9 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	1.86e-05	203	33	5	int:KRTAP5-9
Interaction	NBPF19 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	3.61e-05	233	33	5	int:NBPF19
Interaction	KRTAP10-8 interactions	KRTAP4-4 ZNF775 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	4.20e-05	401	33	6	int:KRTAP10-8
Interaction	NUFIP2 interactions	KRTAP4-4 NELL2 KRTAP4-5 KRTAP4-12 PLSCR1 KRTAP10-11	5.22e-05	417	33	6	int:NUFIP2
Interaction	FBXO34 interactions	KRTAP4-5 KRTAP4-12 KRTAP10-11	9.90e-05	55	33	3	int:FBXO34
Interaction	TRIM42 interactions	KRTAP4-4 TRAF2 KRTAP4-5 PLSCR1	9.94e-05	149	33	4	int:TRIM42
Interaction	SPRY2 interactions	TRAF2 KRTAP4-12 PLSCR1 KRTAP10-11	1.07e-04	152	33	4	int:SPRY2
Interaction	KRTAP10-1 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	1.10e-04	153	33	4	int:KRTAP10-1
Interaction	OTX1 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	1.16e-04	155	33	4	int:OTX1
Interaction	KRTAP10-5 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	1.31e-04	160	33	4	int:KRTAP10-5
Interaction	KRTAP4-12 interactions	KRTAP4-4 KRTAP4-12 PLSCR1 KRTAP10-11	1.34e-04	161	33	4	int:KRTAP4-12
Interaction	KRTAP5-2 interactions	KRTAP4-4 KRTAP4-5 KRTAP10-11	1.42e-04	62	33	3	int:KRTAP5-2
Interaction	KRTAP5-4 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12	1.49e-04	63	33	3	int:KRTAP5-4
Interaction	NPDC1 interactions	KRTAP4-4 KRTAP4-12 PLSCR1	1.63e-04	65	33	3	int:NPDC1
Interaction	TNFRSF18 interactions	TNFRSF18 TRAF2	1.70e-04	12	33	2	int:TNFRSF18
Interaction	KRTAP5-3 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12	1.71e-04	66	33	3	int:KRTAP5-3
Interaction	KRTAP1-3 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	2.24e-04	184	33	4	int:KRTAP1-3
Interaction	FAM107A interactions	TRAF2 KRTAP4-12 PLSCR1	2.30e-04	73	33	3	int:FAM107A
Interaction	ATN1 interactions	NELL2 MEGF8 KRTAP4-12 PLSCR1	2.38e-04	187	33	4	int:ATN1
Interaction	C10orf62 interactions	KRTAP4-12 PLSCR1	2.69e-04	15	33	2	int:C10orf62
Interaction	LELP1 interactions	KRTAP4-5 KRTAP4-12	3.48e-04	17	33	2	int:LELP1
Interaction	CNTFR interactions	KRTAP4-12 PLSCR1	3.48e-04	17	33	2	int:CNTFR
Interaction	NOTCH2NLA interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-10 KRTAP10-11	3.61e-04	381	33	5	int:NOTCH2NLA
Interaction	ADAMTSL4 interactions	KRTAP4-4 KRTAP4-12 PLSCR1 KRTAP10-11	4.19e-04	217	33	4	int:ADAMTSL4
Interaction	KRTAP1-1 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	4.34e-04	219	33	4	int:KRTAP1-1
Interaction	SOX30 interactions	FBXO38 TRAF2	4.37e-04	19	33	2	int:SOX30
Interaction	KRTAP4-11 interactions	KRTAP4-4 PLSCR1 KRTAP10-11	4.55e-04	92	33	3	int:KRTAP4-11
Interaction	ZNF764 interactions	KRTAP4-4 KRTAP4-12 PLSCR1	4.69e-04	93	33	3	int:ZNF764
Interaction	SHFL interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12	5.31e-04	97	33	3	int:SHFL
Interaction	IP6K2 interactions	TRAF2 PLSCR1	5.36e-04	21	33	2	int:IP6K2
Interaction	PRKAB2 interactions	TRAF2 KRTAP4-5 KRTAP4-12 KRTAP10-11	5.56e-04	234	33	4	int:PRKAB2
Interaction	FAM76B interactions	KRTAP4-5 KRTAP4-12 KRTAP10-11	5.64e-04	99	33	3	int:FAM76B
Interaction	KRTAP13-2 interactions	KRTAP4-4 TRAF2 KRTAP4-5	5.64e-04	99	33	3	int:KRTAP13-2
Interaction	NCAPG2 interactions	FBXO38 FBXO5 RIC3	5.80e-04	100	33	3	int:NCAPG2
Interaction	KRTAP9-8 interactions	KRTAP4-4 KRTAP4-5 KRTAP10-11	5.80e-04	100	33	3	int:KRTAP9-8
Interaction	ZBTB40 interactions	FBXO38 NELL2	6.44e-04	23	33	2	int:ZBTB40
Interaction	SPATA3 interactions	KRTAP4-12 KRTAP10-11	7.02e-04	24	33	2	int:SPATA3
Interaction	ATXN7 interactions	NELL2 TRAF2 MEGF8	7.46e-04	109	33	3	int:ATXN7
Interaction	KRTAP10-10 interactions	KRTAP4-4 KRTAP10-10	8.90e-04	27	33	2	int:KRTAP10-10
Interaction	MFNG interactions	DLL1 PLSCR1	8.90e-04	27	33	2	int:MFNG
Interaction	GPRIN2 interactions	KRTAP4-12 PLSCR1	9.57e-04	28	33	2	int:GPRIN2
Interaction	CACNA1A interactions	SCN10A NELL2 MEGF8	1.06e-03	123	33	3	int:CACNA1A
Interaction	KRTAP10-7 interactions	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP10-11	1.28e-03	293	33	4	int:KRTAP10-7
Interaction	ATG12 interactions	TRAF2 KRTAP4-12 PLSCR1 PGAP2	1.33e-03	296	33	4	int:ATG12
Interaction	ZNF587 interactions	PLSCR1 KRTAP10-10 KRTAP10-11	1.38e-03	135	33	3	int:ZNF587
Interaction	AQP1 interactions	KRTAP4-4 TRAF2 KRTAP4-12	1.47e-03	138	33	3	int:AQP1
Interaction	DLK2 interactions	KRTAP4-12 PLSCR1	1.58e-03	36	33	2	int:DLK2
Interaction	NUDT18 interactions	TRAF2 KRTAP4-12	1.86e-03	39	33	2	int:NUDT18
Interaction	DYRK1A interactions	ASTN2 NELL2 TRAF2 HTRA4 ITGB8	1.90e-03	552	33	5	int:DYRK1A
Interaction	ZNF440 interactions	KRTAP4-4 KRTAP4-12	1.95e-03	40	33	2	int:ZNF440
Interaction	CRY1 interactions	TRAF2 KRTAP4-12 PLSCR1	2.33e-03	162	33	3	int:CRY1
Interaction	ZNF497 interactions	KRTAP4-4 KRTAP4-12	2.36e-03	44	33	2	int:ZNF497
Interaction	ZBTB25 interactions	TRAF2 VEGFD	2.36e-03	44	33	2	int:ZBTB25
Interaction	AXIN1 interactions	TRAF2 HTRA4 KRTAP4-12	2.50e-03	166	33	3	int:AXIN1
Cytoband	17q12-q21	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3	1.41e-08	32	38	4	17q12-q21
Cytoband	11q14.3	TRIM64B TRIM64	3.26e-04	32	38	2	11q14.3
Cytoband	Ensembl 112 genes in cytogenetic band chr17q21	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3	6.22e-04	473	38	4	chr17q21
GeneFamily	Keratin associated proteins	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	6.74e-09	109	25	6	619
GeneFamily	Ring finger proteins	TRIM64B TRAF2 TRIM64 TRIM64C MARCHF9	3.25e-05	275	25	5	58
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM64B TRIM64 TRIM64C	2.97e-04	95	25	3	59
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC5 ZDHHC8	4.97e-04	24	25	2	76
GeneFamily	Cyclins\|F-boxes other	FBXO38 FBXO5	1.32e-03	39	25	2	560
CoexpressionAtlas	FacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_1000_k-means-cluster#2	ASTN2 NELL2 DLL1 ITGB8 RIC3	2.34e-05	248	30	5	Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_1000_K2
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#3_top-relative-expression-ranked_100	VEGFD SLCO2A1	4.03e-05	7	30	2	gudmap_kidney_adult_RenalCapsule_k3_100
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-6\|TCGA-Skin / Sample_Type by Project: Shred V9	KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3 KRTAP10-10 KRTAP10-11	2.67e-09	146	38	6	522c32103c24fc26836bb5b642083904682d9292
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma-10\|TCGA-Bladder / Sample_Type by Project: Shred V9	SCN10A KRTAP4-4 KRTAP4-5 KRTAP4-12 KRTAP4-3	8.34e-08	129	38	5	6a201c6344a015e5cf2f79ccf397fd7ad66b6768
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-BM_CD4_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 TNFRSF18 ITGB8 SLCO2A1	1.34e-05	171	38	4	6f49537f8d3cf18e65aa999fec32ed347ce2da3e
ToppCell	facs-Marrow-B-cells-18m-Lymphocytic-CD4-positive,_alpha-beta_T_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PODNL1 TNFRSF18 ITGB8 SLCO2A1	1.34e-05	171	38	4	ab97ae2b127a585f170f028f1c475cdd1b0cdea5
ToppCell	facs-Skin-Telogen-3m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF18 DLL1 VEGFD SLCO2A1	1.91e-05	187	38	4	9c1013720c248ef201d010806b6e7ad24205e8ee
ToppCell	droplet-Skin-nan-21m-Epithelial-basal_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF18 DLL1 VEGFD SLCO2A1	2.03e-05	190	38	4	c1bfc1960a3df49c0f459454a7363804c32418ee
Disease	Osteoarthritis of hip	ASTN2 CHADL	2.14e-04	20	32	2	C0029410
Disease	hip geometry	ASTN2 OTOGL	1.05e-03	44	32	2	EFO_0004685
Disease	ocular hypertension, response to triamcinolone acetonide	OTOGL MARCHF9	1.30e-03	49	32	2	EFO_0006954, EFO_1001069
Disease	Nonsyndromic Deafness	OTOGL OTOG	3.50e-03	81	32	2	C3711374
Disease	osteoarthritis, hip	ASTN2 CHADL	4.49e-03	92	32	2	EFO_1000786
Disease	Inhalant adrenergic use measurement	CHADL ITGB8	4.88e-03	96	32	2	EFO_0009941
Disease	corpus callosum volume measurement	ZDHHC5 DLL1	5.28e-03	100	32	2	EFO_0010299
Disease	eosinophil measurement	ITGB8 MFSD12	6.13e-03	108	32	2	EFO_0803540
Disease	chronic obstructive pulmonary disease	FBXO38 ASTN2 NELL2 ITGB8	6.27e-03	688	32	4	EFO_0000341
Disease	migraine disorder	SCN10A TRMT9B ASTN2	6.72e-03	357	32	3	MONDO_0005277

Protein segments in the cluster

Peptide	Gene	Start	Entry
APCCPRICFPHSQEC	ANTXRL	486	A6NF34
RCEEKGRCPSTCHLC	ASTN2	976	O75129
SCTSPCSCYRPLCRL	PGAP2	101	Q9UHJ9
LFCCPECDPRLSSQC	NELL2	686	Q99435
TDCCTRNCCGPSRPF	PLSCR1	146	O15162
PRCRSCDGFLTCHEC	MEGF8	1001	Q7Z7M0
CGRVSCHTTCYRPTC	KRTAP4-12	171	Q9BQ66
HPSCCVSSCRCPFSC	KRTAP4-3	161	Q9BYR4
PTTCCRTTCFHPICC	KRTAP4-3	176	Q9BYR4
CRPSCCVSRCYRPHC	KRTAP4-4	146	Q9BYR3
CDPKPETCSCCFHED	RIC3	296	Q7Z5B4
CRCDGSVRCTHQPCL	MARCHF9	126	Q86YJ5
CPLRCSCPRVDTVDC	PODNL1	46	Q6PEZ8
GDAESSVCPRCCCHR	FBXO38	766	Q6PIJ6
SVCPRCCCHRPQESQ	FBXO38	771	Q6PIJ6
DPRSIGRFCEHCPTC	ITGB8	616	P26012
PVFDLCRCCRVCPAA	HTRA4	61	P83105
CSCALRPPRCSCSAS	FBXO5	6	Q9UKT4
RNCSAPVSRCEHAPC	DLL1	476	O00548
CGRVSCHTTCYRPTC	KRTAP4-5	151	Q9BYR2
CRPVCSRPACYSLCS	KRTAP10-10	231	P60014
CHPVCRSTCCVPVSS	KRTAP10-11	241	P60412
SCAHVECPPAHTCRC	CRIPAK	26	Q8N1N5
CPRACVCVPESRHSS	CHADL	396	Q6NUI6
LHPCPSELCCRACVS	MFSD12	426	Q6NUT3
DDSFVHRDCISCCPP	OTOGL	391	Q3ZCN5
HRDCISCCPPTCTFE	OTOGL	396	Q3ZCN5
IACCPASCHPRASCV	OTOG	431	Q6ZRI0
VVAHCCCCSSPGPRR	SMIM22	51	K7EJ46
TDSELAPRSUCCHCR	SELENOP	291	P49908
SIHPQSPACRRDCSC	SLCO2A1	436	Q92959
SPACRRDCSCPDSIF	SLCO2A1	441	Q92959
CPERSLSCRHCRAPC	TRAF2	156	Q12933
PDDCFTEGCIRHCPC	SCN10A	1111	Q9Y5Y9
SRPATHSCPECERCF	ZNF775	186	Q96BV0
QPEFHCGDPCCTTCR	TNFRSF18	76	Q9Y5U5
CATCRFYRPPRCSHC	ZDHHC5	106	Q9C0B5
HPPCSECSCSVCFKE	TRMT9B	191	Q9P272
CATCHFYRPPRCSHC	ZDHHC8	106	Q9ULC8
TCSCEDRCPFHTRPC	VEGFD	311	O43915
VTTDCVHSFCRPCLC	TRIM64C	26	A6NLI5
VHSFCRPCLCLCSEE	TRIM64C	31	A6NLI5
VTIDCGHSFCRPCLC	TRIM64	26	A6NGJ6
GHSFCRPCLCLCSEE	TRIM64	31	A6NGJ6
VTIDCGHSFCRPCLC	TRIM64B	26	A6NI03
GHSFCRPCLCLCSEE	TRIM64B	31	A6NI03