Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendodeoxyribonuclease activity, producing 5'-phosphomonoesters

DICER1 DNASE1L3 SLX1A

8.71e-0614593GO:0016888
GeneOntologyMolecularFunctiondeoxyribonuclease I activity

DICER1 DNASE1L3

8.53e-055592GO:0004530
GeneOntologyMolecularFunctionDNA endonuclease activity

DICER1 DNASE1L3 SLX1A

2.98e-0444593GO:0004520
GeneOntologyMolecularFunctionendonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters

DICER1 DNASE1L3 SLX1A

3.40e-0446593GO:0016893
GeneOntologyMolecularFunctionoxidized purine DNA binding

RECQL4 MUTYH

3.80e-0410592GO:0032357
GeneOntologyMolecularFunctionoxidized DNA binding

RECQL4 MUTYH

4.64e-0411592GO:0032356
GeneOntologyMolecularFunctionclathrin heavy chain binding

SNAP91 PICALM

5.56e-0412592GO:0032050
GeneOntologyMolecularFunctionDNA nuclease activity

DICER1 DNASE1L3 SLX1A

1.03e-0367593GO:0004536
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

RECQL4 DICER1 DNASE1L3 MUTYH SLX1A

1.05e-03262595GO:0140097
GeneOntologyMolecularFunction1-phosphatidylinositol binding

SNAP91 PICALM

1.13e-0317592GO:0005545
GeneOntologyCellularComponentextrinsic component of synaptic membrane

SNAP91 TENM2 PICALM

1.31e-0435593GO:0099243
GeneOntologyCellularComponentextrinsic component of presynaptic endocytic zone membrane

SNAP91 PICALM

1.63e-047592GO:0098894
DomainClathrin_AP_2

SNAP91 PICALM

9.48e-062582IPR014712
Domain-

SNAP91 PICALM

9.48e-0625821.20.58.150
DomainRhs_assc_core

TENM3 TENM2

2.84e-053582IPR022385
DomainTox-GHH_dom

TENM3 TENM2

5.66e-054582IPR028916
DomainTen_N

TENM3 TENM2

5.66e-054582IPR009471
DomainTen_N

TENM3 TENM2

5.66e-054582PF06484
DomainANTH_dom

SNAP91 PICALM

5.66e-054582IPR011417
DomainTENEURIN_N

TENM3 TENM2

5.66e-054582PS51361
DomainTox-GHH

TENM3 TENM2

5.66e-054582PF15636
DomainANTH

SNAP91 PICALM

5.66e-054582PF07651
DomainYD

TENM3 TENM2

9.42e-055582IPR006530
DomainENTH

SNAP91 PICALM

3.36e-049582PS50942
DomainENTH

SNAP91 PICALM

3.36e-049582SM00273
DomainENTH

SNAP91 PICALM

4.20e-0410582IPR013809
DomainVWA

CLCA4 COL20A1 COL6A5

7.01e-0456583PF00092
DomainNHL

TENM3 TENM2

7.23e-0413582PS51125
DomainCarboxyPept-like_regulatory

TENM3 TENM2

1.25e-0317582IPR008969
Domain-

CLCA4 COL20A1 COL6A5

1.58e-03745833.40.50.410
Domainfn3

GHR EPHB4 COL20A1 MYOM2

1.61e-03162584PF00041
DomainVWFA

CLCA4 COL20A1 COL6A5

2.12e-0382583PS50234
DomainVWA

CLCA4 COL20A1 COL6A5

2.27e-0384583SM00327
DomainFN3

GHR EPHB4 COL20A1 MYOM2

2.61e-03185584SM00060
Domain-

SNAP91 PICALM

2.94e-03265821.25.40.90
DomainFN3

GHR EPHB4 COL20A1 MYOM2

3.39e-03199584PS50853
DomainVWF_A

CLCA4 COL20A1 COL6A5

3.61e-0399583IPR002035
DomainENTH_VHS

SNAP91 PICALM

3.65e-0329582IPR008942
DomainFN3_dom

GHR EPHB4 COL20A1 MYOM2

4.03e-03209584IPR003961
Domain-

TENM3 TENM2

6.52e-03395822.120.10.30
Domain6-blade_b-propeller_TolB-like

TENM3 TENM2

8.99e-0346582IPR011042
Pubmed

Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.

SHROOM3 MYCBP2 FAM53B YWHAG MAP3K2

9.44e-0710260515778465
Pubmed

Diffusional spread and confinement of newly exocytosed synaptic vesicle proteins.

SNAP91 PICALM

2.93e-06260226399746
Pubmed

A Novel Sequence in AP180 and CALM Promotes Efficient Clathrin Binding and Assembly.

SNAP91 PICALM

2.93e-06260227574975
Pubmed

Turning CALM into excitement: AP180 and CALM in endocytosis and disease.

SNAP91 PICALM

2.93e-06260222639918
Pubmed

Exercise-mediated alteration of hippocampal Dicer mRNA and miRNAs is associated with lower BACE1 gene expression and Aβ1-42 in female 3xTg-AD mice.

BACE1 DICER1

2.93e-06260233052800
Pubmed

The clathrin assembly protein AP180 regulates the generation of amyloid-beta peptide.

SNAP91 PICALM

8.77e-06360219450545
Pubmed

Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer's disease risk factor CALM bidirectionally controls synaptic plasticity.

SNAP91 PICALM

8.77e-06360235613266
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM3 TENM2

1.75e-05460210225957
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM3 TENM2

1.75e-05460212000766
Pubmed

Dicer1-miR-328-Bace1 signalling controls brown adipose tissue differentiation and function.

BACE1 DICER1

1.75e-05460226900752
Pubmed

Clathrin assembly lymphoid myeloid leukemia (CALM) protein: localization in endocytic-coated pits, interactions with clathrin, and the impact of overexpression on clathrin-mediated traffic.

SNAP91 PICALM

2.92e-05560210436022
Pubmed

Role of the clathrin adaptor PICALM in normal hematopoiesis and polycythemia vera pathophysiology.

SNAP91 PICALM

2.92e-05560225552701
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SHROOM3 TENM3 COL20A1 NPLOC4

3.11e-0510360410819331
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

TENM3 TENM2

6.11e-05760210625539
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM3 TENM2

6.11e-05760212915301
Pubmed

Linkage and genome-wide association analysis of obesity-related phenotypes: association of weight with the MGAT1 gene.

CEP112 BICD1

6.11e-05760219851299
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM3 TENM2

8.14e-05860210331952
Pubmed

Proteomic analysis of the NOS2 interactome in human airway epithelial cells.

MYCBP2 AGR2 YWHAG DICER1

9.74e-0513860423438482
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPHB4 PIKFYVE SHROOM3 SH3TC1 MYCBP2 MYO9B SNX8 NDUFA1 ZNF236

1.10e-04110560935748872
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM3 TENM2

1.31e-041060238713721
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

PIKFYVE SNAP91 UNC5B PICALM FAM83B

1.35e-0428560534369648
Pubmed

The netrin receptor UNC5B mediates guidance events controlling morphogenesis of the vascular system.

EPHB4 UNC5B

1.59e-041160215510105
Pubmed

Ran binding protein 9 interacts with Raf kinase but does not contribute to downstream ERK1/2 activation in skeletal myoblasts.

PACSIN3 NPLOC4

1.91e-041260216364241
Pubmed

Genetic pathway-based hierarchical clustering analysis of older adults with cognitive complaints and amnestic mild cognitive impairment using clinical and neuroimaging phenotypes.

BACE1 CASP7

3.03e-041560220468060
Pubmed

Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.

PNMA2 SLX1A BICD1

4.36e-048560319596235
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SHROOM3 MYCBP2 CEP112 FAM53B YWHAG MAP3K2 FAM83B

6.87e-0486160736931259
Pubmed

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

TENM3 UNC5B PACSIN3 PICALM FAM83B

8.02e-0442160536976175
Pubmed

Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.

MYCBP2 BICD1

8.56e-042560212522145
Pubmed

A p53-dependent translational program directs tissue-selective phenotypes in a model of ribosomopathies.

CCNG1 DICER1

9.99e-042760234242585
Pubmed

Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.

SHROOM3 PNMA2 YWHAG MAP3K2 FAM83B

1.04e-0344660524255178
Pubmed

Association between genetic variants in VEGF, ERCC3 and occupational benzene haematotoxicity.

TRPM5 TMEM151B CASP7 MAP3K2

1.12e-0326360419773279
Pubmed

Absence of canonical Smad signaling in ureteral and bladder mesenchyme causes ureteropelvic junction obstruction.

COL20A1 MYOM2

1.32e-033160222282597
Pubmed

Phosphorylated tau interactome in the human Alzheimer's disease brain.

SNAP91 YWHAG CKMT1A

1.34e-0312560332812023
Pubmed

HAUSP regulates c-MYC expression via de-ubiquitination of TRRAP.

CEP112 DICER1

1.58e-033460225925205
Pubmed

A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complex.

RECQL4 PICALM

1.68e-033560223382074
CytobandEnsembl 112 genes in cytogenetic band chr5q34

CCNG1 TENM2

1.33e-0341602chr5q34
GeneFamilyFibronectin type III domain containing

GHR EPHB4 COL20A1 MYOM2

3.82e-04160394555
CoexpressionLAKE_ADULT_KIDNEY_C2_PODOCYTES

GHR TENM3 CEP112 TENM2 PICALM BICD1

8.22e-06212596M39221
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_LINC00343|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 KCNH7 TENM3 MYOM2 PLEKHH2

4.55e-061816059de2f2cc5f02e0ca599c9e0d2cb1e1e4b5aac112
ToppCellSubstantia_nigra-Neuronal|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

MYCBP2 PNMA2 TENM2 YWHAG CKMT1A

5.20e-061866053f889083fcffe516388e9b03a5e23af2010ced33
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB7 CEP112 TENM2 FAM83B CKMT1A

5.62e-061896056f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB7 CEP112 TENM2 FAM83B CKMT1A

5.62e-061896053b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB7 CEP112 TENM2 FAM83B CKMT1A

5.62e-0618960538acb307907fde68b992057714448c1561d69ee3
ToppCellThalamus-Neuronal|Thalamus / BrainAtlas - Mouse McCarroll V32

KCNH7 SNAP91 TENM2 YWHAG CKMT1A

6.22e-06193605712a4acd1167e43543950bc819ff11984e6f718d
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH7 SNAP91 PNMA2 TENM2 CKMT1A

6.22e-06193605461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNH7 SNAP91 PNMA2 TENM2 CKMT1A

6.22e-061936050dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

GHR TENM3 COL6A5 PLEKHH2 TENM2

6.22e-06193605ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 AGR2 TENM2 CKMT1A

4.88e-05149604d259e9137109eeb2662022f0915ca463f5bebdfe
ToppCellEpithelial-Epithelial-B_(AT1-AT2-progenitors)|Epithelial / shred on cell class and cell subclass (v4)

SAMD1 BRINP3 UNC5B PLEKHH2

5.54e-05154604770712806e26f73456fb77a81aa4ef8ec78a21ea
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GHR PNMA2 COL6A5 PLEKHH2

6.13e-05158604e5636c0b608d68bd426a2b446ac508e4512e86a4
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

CLCA4 TENM2 FAM83B CKMT1A

6.43e-05160604830f17bad94de05612fe6d53d39e42a4b3f3e2f3
ToppCell390C-Epithelial_cells-Epithelial-H_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

CLCA4 TENM2 FAM83B CKMT1A

6.43e-0516060418ae6822915d16699beb9047baeef9b006901a35
ToppCell10x5'-Liver-Lymphocytic_Invariant-Inducer-like-ILC3|Liver / Manually curated celltypes from each tissue

EVA1C COL20A1 CEP112 PLEKHH2

6.91e-051636047f61483eeb1fde21843c6391468e13cb0cc2a89f
ToppCellfacs-GAT-Fat-24m-Epithelial|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB7 CLCA4 AGR2 CKMT1A

8.70e-05173604815ba48a9222ea09ba8005e2d2f7c5addf118ad1
ToppCellfacs-GAT-Fat-24m-Epithelial-nan|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB7 CLCA4 AGR2 CKMT1A

8.70e-0517360498e464d9e6d6b69421e9e4041b638b6825247f60
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

EPHB4 AGR2 PNMA2 PACSIN3

8.70e-05173604ef8d720b99470fe1953661f6e66bc0366266bdb6
ToppCellfacs-GAT-Fat-24m-Epithelial-epithelial_cell|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HOXB7 CLCA4 AGR2 CKMT1A

8.70e-051736043e6f0a08eddfd61871f7a85acccf6d539af6ebda
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_4|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

EPHB4 AGR2 PNMA2 PACSIN3

8.90e-05174604110369f6b78de34a6d934b5b47cecd023347bc80
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 TENM3 MYOM2 PLEKHH2

9.30e-051766040710689e66deba179b0a8038cdd56b4834984f12
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 CLCA4 AGR2 CKMT1A

9.93e-05179604bc93883c2094f2e5bfed79facd4994a23968d875
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 CLCA4 AGR2 CKMT1A

9.93e-051796040cef6d2eab2015cac0dd340532b24bfec9707330
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-plasmablast-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SAG PIERCE1 RECQL4 PACSIN3

9.93e-05179604021d782134126c6f7dce6b6ea50cc54bdaa39987
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 TENM3 MYOM2 PLEKHH2

9.93e-051796041ac79c82c52fa95bb4e170ab20fec0f648db2134
ToppCellfacs-Brain_Myeloid-Cortex-24m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 CLCA4 AGR2 CKMT1A

9.93e-05179604bb2410b3934fcc53396b96b48e0d9843df159b89
ToppCellfacs-Brain_Myeloid-Cortex-24m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPHB4 CLCA4 AGR2 CKMT1A

9.93e-05179604065241799cea30da62cb3b6f2f1970bd1b0f4e2b
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLCA4 AGR2 PACSIN3 CKMT1A

1.04e-04181604faff2a34e391d053a17c926540e6cb46d94dd629
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CLCA4 AGR2 PACSIN3 CKMT1A

1.04e-0418160458651853f9c715075889856793df66ebe00c04f1
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

GHR COL6A5 PLEKHH2 TENM2

1.04e-041816049ede19228ba5c0668a9c06c915510b95585216ef
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CLCA4 AGR2 PACSIN3 CKMT1A

1.04e-041816045a9c332c0bf07cc20eaf8cf77b45e73668a6467d
ToppCellBAL-Control-Epithelial-Epithelial-Basal/Club-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CLCA4 AGR2 PACSIN3 CKMT1A

1.04e-04181604488a517f6e5543b648a2e72e0e04332fad776de6
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TENM3 COL20A1 CEP128 BICD1

1.06e-04182604a1c0e4090a9e7aa4941a40c817d178de144888b6
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 AGR2 TENM2 CKMT1A

1.06e-04182604b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 AGR2 TENM2 CKMT1A

1.06e-04182604cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCellControl-APC-like-Dendritic_cells|Control / group, cell type (main and fine annotations)

SH3TC1 SNX8 PICALM DNASE1L3

1.08e-041836048f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCellControl-APC-like|Control / group, cell type (main and fine annotations)

SH3TC1 SNX8 PICALM DNASE1L3

1.08e-04183604c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM3 AGR2 PACSIN3 PLEKHH2

1.10e-04184604e123ad8ee46a032825a0bd4b3586ddcb3eda03d4
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CACNG5|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

GHR BRINP3 PLEKHH2 TENM2

1.10e-04184604658f2e522055e88c92bc482a845c40f8f5f1a8e3
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C TENM3 PLEKHH2 BICD1

1.13e-0418560434fcfd635c828dad9643bbf1c908d79282d6f5d9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C TENM3 PLEKHH2 BICD1

1.13e-041856048816f2909ed11833ff3d0ed96b9cb6d6fe9e1578
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 AGR2 TENM2 CKMT1A

1.15e-04186604246503fd4e6ae24041c606b069eb5fb313e60f73
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLCA4 AGR2 TENM2 CKMT1A

1.15e-04186604ef93ac469eb4f63db036f14b442c1503b8c6de38
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|356C / Donor, Lineage, Cell class and subclass (all cells)

SAMD1 AGR2 RECQL4 PACSIN3

1.15e-04186604189b75aa98903f1cb65b624524ba6c30df7e42ff
ToppCell356C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|356C / Donor, Lineage, Cell class and subclass (all cells)

SAMD1 AGR2 RECQL4 PACSIN3

1.15e-04186604261891d0b148e285339ae0b9e36136ceabd9b6f5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C TENM3 PLEKHH2 BICD1

1.20e-04188604874404a4fd9aa42873f6c53dc42da22d3b0fdb9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

EVA1C TENM3 PLEKHH2 BICD1

1.20e-04188604b21e93a70583c30d05c0833cd3d4d4bca44a039e
ToppCellfacs-Trachea-24m-Epithelial-airway_epithelial|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CLCA4 PIERCE1 AGR2 CKMT1A

1.25e-04190604576c45a30a4808b47433bc6c2c41396135556c40
ToppCellSevere-Lymphoid-NK-Treg|Severe / Condition, Lineage, Cell class and cell subclass

HOXB7 TRMT44 NVL BICD1

1.25e-04190604e67803bf55a3f8e47a69ff1829c9100f870d7527
ToppCellControl-Epithelial-Basal/Club|Control / Disease group,lineage and cell class (2021.01.30)

CLCA4 AGR2 PACSIN3 CKMT1A

1.25e-04190604799b0b1c4bdbe04ee0fc34d0be9e02b5992774a0
ToppCellEntopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 TENM2 YWHAG CKMT1A

1.27e-041916045d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

SAMD1 TRMT44 MYOM2 DICER1

1.27e-04191604cadb7a9de16f4bb21606de0e25cddd2d748c7f0b
ToppCellEntopeduncular-Neuronal-Inhibitory|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 TENM2 YWHAG CKMT1A

1.27e-0419160473dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BRINP3 KCNH7 PLEKHH2 TENM2

1.30e-0419260425460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCellEntopeduncular-Neuronal|Entopeduncular / BrainAtlas - Mouse McCarroll V32

MYCBP2 TENM2 YWHAG CKMT1A

1.30e-041926044c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCellHippocampus-Neuronal|Hippocampus / BrainAtlas - Mouse McCarroll V32

SNAP91 PNMA2 YWHAG CKMT1A

1.35e-041946048aeb347b3024354c9505f4f0fddf0b843489dc6b
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 AGR2 PACSIN3 CKMT1A

1.38e-0419560424d226f89dd337c22728688e4b40ca082a0e1fe1
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SNAP91 PNMA2 TENM2 CKMT1A

1.38e-04195604ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellTracheal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SAG SH3TC1 SNX8 DNASE1L3

1.41e-04196604b71d711be5609115b00a57700885aca608920896
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_secretory|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 SHROOM3 AGR2 CKMT1A

1.49e-04199604a8bfc0b93ad9968cf52a25be86995ffe436bd636
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CLCA4 PACSIN3 FAM83B CKMT1A

1.49e-04199604c88a28a73f54dc571f2ff1e4b55073f83cbead2c
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_only / Treatment groups by lineage, cell group, cell type

TENM3 MYCBP2 COL6A5 PLEKHH2

1.49e-04199604fde2b65afde69f402f1b7b056eaa266e9fd5b227
ToppCellLPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TENM3 MYCBP2 COL6A5 PLEKHH2

1.49e-04199604a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCellLPS_only-Mesenchymal_fibroblastic-Fibroblasts|LPS_only / Treatment groups by lineage, cell group, cell type

TENM3 MYCBP2 COL6A5 PLEKHH2

1.49e-041996041a0add79f4e34078b3475eb11c85a4234bda197c
ToppCellLPS_only-Mesenchymal_fibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

TENM3 MYCBP2 COL6A5 PLEKHH2

1.49e-04199604211c3a08f2d484ab7a3368006767289088f0d957
ToppCellBronchial-10x5prime-Epithelial-Epi_airway_basal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CLCA4 AGR2 PACSIN3 FAM83B

1.52e-04200604afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCellMacroglial-Polydendrocytes-PDGFRA---|Macroglial / cells hierarchy compared to all cells using T-Statistic

GHR BRINP3 COL20A1 PLEKHH2

1.52e-042006044fc3de4bff7ed2bf40b38462c4b4e9b87af6a4ca
ToppCellMacroglial-Polydendrocytes-PDGFRA-|Macroglial / cells hierarchy compared to all cells using T-Statistic

GHR BRINP3 COL20A1 PLEKHH2

1.52e-04200604f17b5a54e8f9eba9dcd0808ba4e8d275ac41bce2
ToppCellMacroglial-Polydendrocytes-PDGFRA--|Macroglial / cells hierarchy compared to all cells using T-Statistic

GHR BRINP3 COL20A1 PLEKHH2

1.52e-04200604cc3409518f8b436ea92deb955e81114b3f410ff7
ToppCellMacroglial-Polydendrocytes-PDGFRA----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

GHR BRINP3 COL20A1 PLEKHH2

1.52e-04200604310cd53db1c137f6af74e6ae682221d7ac27310c
ToppCellMacroglial-Polydendrocytes-PDGFRA|Macroglial / cells hierarchy compared to all cells using T-Statistic

GHR BRINP3 COL20A1 PLEKHH2

1.52e-04200604c24a3099e3d96d8b72f6d05286bb355d661a0377
ToppCellMacroglial-Polydendrocytes|Macroglial / cells hierarchy compared to all cells using T-Statistic

GHR BRINP3 COL20A1 PLEKHH2

1.52e-04200604961858738ce35db8760c8c2e136f8369bc444ccf
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPHB4 CEP112 UNC5B

1.92e-04836031ab68323518adc7fd0a459b41fad12d60f97eb5c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-CR-CR_Lhx5|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EPHB4 CEP112 UNC5B

1.92e-048360375b27d91a4473286f4b40027e96ac5246f5abe5b
ToppCellEntopeduncular-Macroglia-POLYDENDROCYTE-P1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

TRPM5 COL20A1 BACE1

3.13e-0498603fca0baf13520c53edb6da2fe3eb152fbd44df5ed
Diseaseplasma renin activity measurement

GHR TENM3

1.31e-049572EFO_0006828
Diseaseganglion cell inner plexiform layer thickness measurement

SNAP91 NPLOC4

1.34e-0328572EFO_0600005
Diseasemuscular atrophy (biomarker_via_orthology)

GHR CCNG1

1.44e-0329572DOID:767 (biomarker_via_orthology)
Diseaseaspartate aminotransferase measurement

SHROOM3 OR4P4 SH3TC1 CEP112 SNX8 LCT DNASE1L3

1.73e-03904577EFO_0004736

Protein segments in the cluster

PeptideGeneStartEntry
YRYLAEVATGEKRAT

YWHAG

131

P61981
TVRADITGRYSNRLY

AGR2

136

O95994
RSRQGFSTRYKIYRE

BRINP3

66

Q76B58
QLSSTYRDLRKGVYV

BACE1

116

P56817
DGRYSKYRVRRNSLQ

CEP128

996

Q6ZU80
DYYRQSRVTRSGSLK

BICD1

536

Q96G01
YSREQYTGKLRVRSH

CEP112

156

Q8N8E3
STFIRRYSRYLNEKA

SNAP91

121

O60641
SRDKSVTIYLGNRDY

SAG

21

P10523
TEYRSYVQSKGRARA

DICER1

541

Q9UPY3
ASDLQRVYSIDYGRR

NVL

36

O15381
GRTARQLKHSYYRIT

CCNG1

271

P51959
GYRTQKAVSVYRTSN

PIERCE1

46

Q5BN46
ASYLVQVRARSEAGY

EPHB4

501

P54760
RVARKLDRYSEYGAA

KCNH7

536

Q9NS40
KHYVYSTLTRNRVRQ

FAM83B

681

Q5T0W9
VEKRRCYSGGSVQRY

FAM53B

141

Q14153
YTIRAYSAERRSKAL

OR4P4

221

Q8NGL7
RKGTVRYSRNKDTYF

NPLOC4

321

Q8TAT6
AYGALTENVTRKYTR

MAP3K2

451

Q9Y2U5
RTARASARYYTEVIT

LCT

1346

P09848
RGYKTAKAARNDVYR

GNL1

486

P36915
SRRTAQVRYLKTYQE

PNMA2

246

Q9UL42
YNADYVRGRLTTSRD

IGHV8-51-1

76

P0DTE2
EGTRTVRLTYKNRLY

PLEKHH2

1206

Q8IVE3
DRKRGRQTYTRYQTL

HOXB7

136

P09629
KRETLRGADSAYYQV

PIKFYVE

1761

Q9Y2I7
IYSATYGRRTQERDI

EVA1C

186

P58658
NYVISSRLGRNTYKE

DNASE1L3

86

Q13609
YEVRVRSKQRNSGNY

GHR

226

P10912
KYRVLVSAIYAAGRS

COL20A1

806

Q9P218
RETEGKDSKRNYYSR

GJA9

371

P57773
KRTYAGANVRRVAVF

COL6A5

1856

A8TX70
RSIKTTRDRVPTYQY

CASP7

46

P55210
QAYVVLGSATLRRKY

DNAJC30

96

Q96LL9
AVLRVSYKGSISYRN

SAMD1

81

Q6SPF0
DRRISGVDRYYVSKG

NDUFA1

51

O15239
SGYFDERYVLSSRVR

CKMT1A

151

P12532
YRRAAKYDVISVQGT

KRBA2

156

Q6ZNG9
YRNYGQAKLGREVSR

MS4A13

96

Q5J8X5
KAATGVRVRALYDYA

PACSIN3

361

Q9UKS6
GRYSRRQSKKTQYRE

TRMT44

456

Q8IYL2
EVSSQRFKSSVYRRY

SNX8

96

Q9Y5X2
TRQVTRYRNGDAYTT

TMEM151B

176

Q8IW70
LYREYRTLKRTTGQA

RECQL4

41

O94761
YVKTVYDTRRGVSAE

SHROOM3

306

Q8TF72
TGRTRQAAESYYRAL

SH3TC1

876

Q8TE82
YVSDTNSRRIYRVKS

TENM2

1301

Q9NT68
NVKYAVRLRNYGSRT

MYCBP2

1826

O75592
YYSRGRRLQEGARKV

MUTYH

176

Q9UIF7
TAYTENGRYSLKVRA

CLCA4

666

Q14CN2
STFIRRYSRYLNEKA

PICALM

121

Q13492
TYGRLQELYRSVSRK

TRPM5

411

Q9NZQ8
GDLYVSDTNTRRIYR

TENM3

1226

Q9P273
AGTTKSRRAYVRIAY

UNC5B

136

Q8IZJ1
YKIRVSSTRSYNRNI

ZNF236

176

Q9UL36
YRGRVYVGFTVNTAR

SLX1A

26

Q9BQ83
DFQSYGRQRKARTYI

TTLL13

186

A6NNM8
TVRIRRSGYSAKYTF

MYO9B

881

Q13459
RSRYQSLVAAYGEAK

MYOM2

86

P54296