Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionextracellular matrix structural constituent

LAMB1 COL24A1 DPT COL10A1

1.27e-05188164GO:0005201
GeneOntologyMolecularFunctionextracellular matrix structural constituent conferring tensile strength

COL24A1 COL10A1

6.10e-0446162GO:0030020
GeneOntologyMolecularFunctiontranscription corepressor activity

TLE5 TLE1 TLE3

7.47e-04229163GO:0003714
GeneOntologyMolecularFunctionstructural molecule activity

LAMB1 COL24A1 DPT COL10A1

4.66e-03891164GO:0005198
GeneOntologyBiologicalProcessextracellular matrix organization

LAMB1 COL24A1 DPT COL10A1

1.68e-04377164GO:0030198
GeneOntologyBiologicalProcessextracellular structure organization

LAMB1 COL24A1 DPT COL10A1

1.70e-04378164GO:0043062
GeneOntologyBiologicalProcessexternal encapsulating structure organization

LAMB1 COL24A1 DPT COL10A1

1.71e-04379164GO:0045229
GeneOntologyBiologicalProcessregulation of anoikis

TLE5 TLE1

1.81e-0426162GO:2000209
GeneOntologyBiologicalProcessnegative regulation of canonical Wnt signaling pathway

TLE5 TLE1 TLE3

2.13e-04154163GO:0090090
GeneOntologyBiologicalProcessanoikis

TLE5 TLE1

3.70e-0437162GO:0043276
GeneOntologyBiologicalProcessnegative regulation of Wnt signaling pathway

TLE5 TLE1 TLE3

4.26e-04195163GO:0030178
GeneOntologyCellularComponentbeta-catenin-TCF complex

TLE1 TLE3

4.26e-0513162GO:1990907
GeneOntologyCellularComponentcollagen-containing extracellular matrix

LAMB1 COL24A1 DPT COL10A1

5.83e-04530164GO:0062023
GeneOntologyCellularComponentextracellular matrix

LAMB1 COL24A1 DPT COL10A1

1.29e-03656164GO:0031012
GeneOntologyCellularComponentexternal encapsulating structure

LAMB1 COL24A1 DPT COL10A1

1.31e-03658164GO:0030312
GeneOntologyCellularComponentendoplasmic reticulum lumen

LAMB1 COL24A1 COL10A1

1.91e-03332163GO:0005788
GeneOntologyCellularComponentcollagen trimer

COL24A1 COL10A1

2.02e-0388162GO:0005581
MousePhenodecreased neural crest cell number

PHOX2B EFNB2

8.33e-0513152MP:0009843
MousePhenosmall trigeminal ganglion

PHOX2B EFNB2

2.02e-0420152MP:0001093
MousePhenoabnormal adipose tissue development

RETSAT TLE3

2.23e-0421152MP:0011167
MousePhenoabnormal neural crest cell morphology

PHOX2B EFNB2

4.59e-0430152MP:0009845
MousePhenoabnormal multipotent stem cell morphology

PHOX2B EFNB2

4.91e-0431152MP:0002400
MousePhenoabnormal neural crest morphology

PHOX2B EFNB2

5.23e-0432152MP:0009846
MousePhenoabnormal neural crest cell migration

PHOX2B EFNB2

5.91e-0434152MP:0002950
MousePhenoabnormal pluripotent precursor cell morphology

PHOX2B EFNB2

9.03e-0442152MP:0002399
MousePhenoabnormal neural crest cell physiology

PHOX2B EFNB2

9.46e-0443152MP:0012745
DomainGroucho/TLE_N

TLE5 TLE1 TLE3

5.15e-095163IPR005617
DomainTLE_N

TLE5 TLE1 TLE3

5.15e-095163PF03920
DomainPrefoldin

TLE5 LAMB1 TLE1 TLE3

3.57e-0772164IPR009053
DomainGroucho_enhance

TLE1 TLE3

6.87e-065162IPR009146
DomainCollagen

COL24A1 COL10A1

2.36e-0385162PF01391
DomainCollagen

COL24A1 COL10A1

2.36e-0385162IPR008160
DomainWD40_repeat_CS

TLE1 TLE3

8.48e-03164162IPR019775
DomainWD40

TLE1 TLE3

2.02e-02259162PF00400
DomainWD40

TLE1 TLE3

2.16e-02268162SM00320
DomainWD40_repeat

TLE1 TLE3

2.22e-02272162IPR001680
DomainWD_REPEATS_1

TLE1 TLE3

2.31e-02278162PS00678
DomainWD_REPEATS_2

TLE1 TLE3

2.32e-02279162PS50082
DomainWD_REPEATS_REGION

TLE1 TLE3

2.32e-02279162PS50294
DomainWD40_repeat_dom

TLE1 TLE3

2.61e-02297162IPR017986
Domain-

TLE1 TLE3

3.23e-023331622.130.10.10
DomainWD40/YVTN_repeat-like_dom

TLE1 TLE3

3.26e-02335162IPR015943
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TLE5 TLE1 TLE3

2.82e-0714143M27402
PathwayREACTOME_REPRESSION_OF_WNT_TARGET_GENES

TLE1 TLE3

4.10e-0510142MM15156
PathwayREACTOME_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX

TLE5 TLE1 TLE3

7.34e-0585143M27079
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TLE1 TLE3

2.94e-0426142MM14793
PathwayREACTOME_MET_ACTIVATES_PTK2_SIGNALING

LAMB1 COL24A1

3.92e-0430142M27772
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

TLE1 TLE3

4.47e-0432142MM14975
PathwayREACTOME_MET_PROMOTES_CELL_MOTILITY

LAMB1 COL24A1

7.35e-0441142M27778
PathwayREACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX

TLE1 TLE3

7.71e-0442142M27272
PathwayREACTOME_COLLAGEN_CHAIN_TRIMERIZATION

COL24A1 COL10A1

8.46e-0444142M27812
PathwayPID_PS1_PATHWAY

TLE5 TLE1

9.25e-0446142M70
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

TLE1 TLE3

1.01e-0348142M611
PathwayREACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS

LAMB1 COL10A1

1.52e-0359142M27218
PathwayREACTOME_ASSEMBLY_OF_COLLAGEN_FIBRILS_AND_OTHER_MULTIMERIC_STRUCTURES

COL24A1 COL10A1

1.62e-0361142M27103
PathwayREACTOME_COLLAGEN_BIOSYNTHESIS_AND_MODIFYING_ENZYMES

COL24A1 COL10A1

1.95e-0367142M26999
PathwayREACTOME_SIGNALING_BY_NOTCH1

TLE1 TLE3

2.37e-0374142M616
PathwayREACTOME_DEGRADATION_OF_BETA_CATENIN_BY_THE_DESTRUCTION_COMPLEX

TLE1 TLE3

2.70e-0379142MM14754
PathwayREACTOME_SIGNALING_BY_MET

LAMB1 COL24A1

2.70e-0379142M27643
PathwayPID_BETA_CATENIN_NUC_PATHWAY

TLE5 TLE1

2.77e-0380142M223
PathwayREACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION

LAMB1 COL24A1 COL10A1

2.92e-03300143M610
PathwayWNT_SIGNALING

TLE5 TLE1

3.41e-0389142M5493
PathwayREACTOME_COLLAGEN_FORMATION

COL24A1 COL10A1

3.49e-0390142M631
PathwayREACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX

TLE1 TLE3

3.57e-0391142M27101
PathwayREACTOME_SIGNALING_BY_WNT

TLE5 TLE1 TLE3

3.82e-03330143M7847
Pubmed

Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube.

TLE5 TLE1 TLE3

3.19e-10416311290324
Pubmed

Grg3, a murine Groucho-related gene, is expressed in the developing nervous system and in mesenchyme-induced epithelial structures.

TLE5 TLE1 TLE3

7.98e-1051638989517
Pubmed

Molecular cloning and expression of mouse and human cDNA encoding AES and ESG proteins with strong similarity to Drosophila enhancer of split groucho protein.

TLE5 TLE1 TLE3

7.98e-1051638365415
Pubmed

Transducin-like enhancer of split proteins, the human homologs of Drosophila groucho, interact with hepatic nuclear factor 3beta.

TLE5 TLE1 TLE3

7.98e-10516310748198
Pubmed

Transcripts of Grg4, a murine groucho-related gene, are detected in adjacent tissues to other murine neurogenic gene homologues during embryonic development.

TLE5 TLE1 TLE3

1.60e-0961638892234
Pubmed

Protein characterization and targeted disruption of Grg, a mouse gene related to the groucho transcript of the Drosophila Enhancer of split complex.

TLE5 TLE1 TLE3

1.60e-0961638573724
Pubmed

A Gro/TLE-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.

TLE5 TLE1 TLE3

2.79e-09716324024827
Pubmed

A comparison of Notch, Hes and Grg expression during murine embryonic and post-natal development.

TLE5 TLE1 TLE3

4.47e-09816310512199
Pubmed

The Groucho-related gene family regulates the gonadotropin-releasing hormone gene through interaction with the homeodomain proteins MSX1 and OCT1.

TLE5 TLE1 TLE3

4.47e-09816316002402
Pubmed

Six3 and Six6 activity is modulated by members of the groucho family.

TLE5 TLE1 TLE3

4.47e-09816312441302
Pubmed

All Tcf HMG box transcription factors interact with Groucho-related co-repressors.

TLE5 TLE1 TLE3

1.75e-081216311266540
Pubmed

The transcriptional co-repressor Grg3/Tle3 promotes pancreatic endocrine progenitor delamination and β-cell differentiation.

TLE5 TLE1 TLE3

6.49e-081816322434868
Pubmed

Expression of Groucho/TLE proteins during pancreas development.

TLE5 TLE1 TLE3

1.61e-072416318778483
Pubmed

Differential functions of TLE1 and TLE3 depending on a specific phosphorylation site.

TLE1 TLE3

1.98e-07216233571907
Pubmed

Groucho/TLE family proteins and transcriptional repression.

TLE1 TLE3

1.98e-07216210831834
Pubmed

Grg1 acts as a lung-specific oncogene in a transgenic mouse model.

TLE5 TLE1

1.98e-07216216452182
Pubmed

Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia.

TLE1 TLE3

5.95e-0731628808280
Pubmed

TLE1 is an anoikis regulator and is downregulated by Bit1 in breast cancer cells.

TLE5 TLE1

5.95e-07316222952044
Pubmed

The transcription co-repressor TLE1 interacted with the intracellular region of gpl30 through its Q domain.

TLE5 TLE1

5.95e-07316212030375
Pubmed

Tle corepressors are differentially partitioned to instruct CD8+ T cell lineage choice and identity.

TLE1 TLE3

5.95e-07316230045946
Pubmed

Transducin-like enhancer of Split-1 (TLE1) combines with Forkhead box protein G1 (FoxG1) to promote neuronal survival.

TLE5 TLE1

5.95e-07316222354967
Pubmed

Inhibition of nuclear factor-kappaB-mediated transcription by association with the amino-terminal enhancer of split, a Groucho-related protein lacking WD40 repeats.

TLE5 TLE1

5.95e-07316210660609
Pubmed

Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.

LAMB1 COL24A1 DPT COL10A1

6.29e-0715316425037231
Pubmed

The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.

LAMB1 COL24A1 DPT COL10A1

8.92e-0716716422159717
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

LAMB1 COL24A1 DPT COL10A1

1.08e-0617516428071719
Pubmed

Corepressors TLE1 and TLE3 interact with HESX1 and PROP1.

TLE1 TLE3

1.19e-06416220181723
Pubmed

PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins.

TLE5 TLE1

1.19e-0641629887105
Pubmed

Suppression of colon cancer metastasis by Aes through inhibition of Notch signaling.

TLE5 TLE1

1.19e-06416221251616
Pubmed

A role for cell cycle-regulated phosphorylation in Groucho-mediated transcriptional repression.

TLE1 TLE3

1.19e-06416212397081
Pubmed

TLE expression correlates with mouse embryonic segmentation, neurogenesis, and epithelial determination.

TLE1 TLE3

1.19e-0641628645603
Pubmed

Dynamic expression of Groucho-related genes Grg1 and Grg3 in foregut endoderm and antagonism of differentiation.

TLE1 TLE3

1.19e-06416220108349
Pubmed

Modulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafish.

TLE1 TLE3

1.19e-06416221666599
Pubmed

The winged-helix protein brain factor 1 interacts with groucho and hes proteins to repress transcription.

TLE1 TLE3

1.98e-06516211238932
Pubmed

Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.

TLE1 TLE3

1.98e-0651621303260
Pubmed

Separating genetic and hemodynamic defects in neuropilin 1 knockout embryos.

COL10A1 EFNB2

2.97e-06616218550715
Pubmed

The role of kreisler in segmentation during hindbrain development.

PHOX2B EFNB2

2.97e-06616210395784
Pubmed

A mitochondrial protein, Bit1, mediates apoptosis regulated by integrins and Groucho/TLE corepressors.

TLE5 TLE1

4.16e-06716215006356
Pubmed

Nolz1 promotes striatal neurogenesis through the regulation of retinoic acid signaling.

TLE1 TLE3

5.55e-06816220735826
Pubmed

Constitutive scaffolding of multiple Wnt enhanceosome components by Legless/BCL9.

TLE1 TLE3

5.55e-06816228296634
Pubmed

Grg3/TLE3 and Grg1/TLE1 induce monohormonal pancreatic β-cells while repressing α-cell functions.

TLE1 TLE3

8.91e-061016224487024
Pubmed

Spatial distribution of the full-length members of the Grg family during embryonic neurogenesis reveals a "Grg-mediated repression map" in the mouse telencephalon.

TLE1 TLE3

8.91e-061016230571765
Pubmed

Coexpression of Cux-1 and Notch signaling pathway components during kidney development.

TLE1 TLE3

1.09e-051116215499562
Pubmed

Spatiotemporal mapping of vascularization and innervation in the fetal murine intestine.

PHOX2B EFNB2

1.09e-051116225138596
Pubmed

Neurog2 simultaneously activates and represses alternative gene expression programs in the developing neocortex.

TLE1 TLE3

1.54e-051316222735158
Pubmed

Nkx2.2-repressor activity is sufficient to specify alpha-cells and a small number of beta-cells in the pancreatic islet.

TLE1 TLE3

1.80e-051416217202186
Pubmed

Developmental restriction of Mash-2 expression in trophoblast correlates with potential activation of the notch-2 pathway.

TLE1 TLE3

2.08e-05151629291577
Pubmed

Coronary veins determine the pattern of sympathetic innervation in the developing heart.

PHOX2B EFNB2

2.37e-051616223462468
Pubmed

Groucho co-repressor proteins regulate β cell development and proliferation by repressing Foxa1 in the developing mouse pancreas.

TLE1 TLE3

3.02e-051816233658226
Pubmed

TCF and Groucho-related genes influence pituitary growth and development.

TLE5 TLE3

3.02e-051816212907761
Pubmed

Temporal regulation of a paired-like homeodomain repressor/TLE corepressor complex and a related activator is required for pituitary organogenesis.

TLE1 TLE3

3.02e-051816211731482
Pubmed

Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.

LAMB1 COL24A1 DPT

3.09e-0513516328675934
Pubmed

Transcriptional regulation of cortical neuron migration by POU domain factors.

TLE1 TLE3

3.75e-052016211859196
Pubmed

CUL4-DDB1 ubiquitin ligase interacts with multiple WD40-repeat proteins and regulates histone methylation.

TLE1 TLE3

7.45e-052816217041588
Pubmed

HMGB1 interacts with many apparently unrelated proteins by recognizing short amino acid sequences.

TLE5 TLE1

9.76e-053216211748221
Pubmed

Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.

TLE1 TLE3

1.10e-043416230894540
Pubmed

Nephric duct insertion requires EphA4/EphA7 signaling from the pericloacal mesenchyme.

DPT EFNB2

1.61e-044116225139858
Pubmed

Genetic variations strongly influence phenotypic outcome in the mouse retina.

RETSAT TLE1

2.03e-044616221779340
Pubmed

GATA6 is a crucial factor for Myocd expression in the visceral smooth muscle cell differentiation program of the murine ureter.

PHOX2B DPT

2.21e-044816235905011
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TLE5 TLE1 TLE3

2.35e-0426816333640491
Pubmed

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.

TLE5 TLE1 TLE3

3.21e-0429816332353859
Pubmed

Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.

LAMB1 DPT

3.93e-046416222261194
InteractionSIX6 interactions

TLE5 TLE1 TLE3

6.75e-0811163int:SIX6
InteractionRIPPLY2 interactions

TLE5 TLE1 TLE3

4.64e-0720163int:RIPPLY2
InteractionSIX3 interactions

TLE5 TLE1 TLE3

4.64e-0720163int:SIX3
InteractionSIX2 interactions

TLE5 TLE1 TLE3

1.48e-0629163int:SIX2
InteractionISX interactions

TLE5 TLE1 TLE3

1.82e-0631163int:ISX
InteractionHLX interactions

TLE5 TLE1 TLE3

3.14e-0637163int:HLX
InteractionGFI1B interactions

TLE5 LAMB1 TLE1 TLE3

3.39e-06136164int:GFI1B
InteractionSTARD7 interactions

TLE5 TLE1 TLE3

3.69e-0639163int:STARD7
InteractionSIX1 interactions

TLE5 TLE1 TLE3

7.40e-0649163int:SIX1
InteractionHES6 interactions

TLE5 TLE1 TLE3

8.86e-0652163int:HES6
InteractionHHEX interactions

TLE5 TLE1 TLE3

9.94e-0654163int:HHEX
InteractionRIPPLY1 interactions

TLE5 TLE1 TLE3

1.05e-0555163int:RIPPLY1
InteractionVSX1 interactions

TLE5 TLE1 TLE3

1.82e-0566163int:VSX1
InteractionMYH1 interactions

KCNMA1 MAGEB5 TLE3

2.79e-0576163int:MYH1
InteractionPRDM1 interactions

TLE5 TLE1 TLE3

3.76e-0584163int:PRDM1
InteractionPAX2 interactions

TLE5 TLE1 TLE3

3.90e-0585163int:PAX2
InteractionGSC interactions

TLE5 TLE1 TLE3

4.18e-0587163int:GSC
InteractionTLE4 interactions

TLE5 TLE1 TLE3

4.94e-0592163int:TLE4
InteractionFOXI1 interactions

TLE5 TLE1 TLE3

4.94e-0592163int:FOXI1
InteractionVENTX interactions

TLE5 TLE1 TLE3

7.12e-05104163int:VENTX
InteractionEN1 interactions

TLE5 TLE1 TLE3

8.41e-05110163int:EN1
InteractionPAX8 interactions

TLE5 TLE1 TLE3

8.64e-05111163int:PAX8
InteractionRIPPLY3 interactions

TLE5 TLE1 TLE3

8.88e-05112163int:RIPPLY3
InteractionTBR1 interactions

TLE5 TLE1 TLE3

9.11e-05113163int:TBR1
InteractionTBXT interactions

TLE5 TLE1 TLE3

9.85e-05116163int:TBXT
InteractionRUNX1 interactions

TLE5 TLE1 TLE3 ABCA2

1.02e-04324164int:RUNX1
InteractionPAX7 interactions

TLE5 TLE1 TLE3

1.20e-04124163int:PAX7
InteractionMYL11 interactions

KCNMA1 TLE3

1.23e-0421162int:MYL11
InteractionTBX20 interactions

TLE1 TLE3

1.23e-0421162int:TBX20
InteractionPAX9 interactions

TLE5 TLE1 TLE3

1.38e-04130163int:PAX9
InteractionTLE2 interactions

TLE5 TLE1 TLE3

1.58e-04136163int:TLE2
InteractionMFAP4 interactions

TLE5 TLE1 TLE3

1.68e-04139163int:MFAP4
InteractionFOXQ1 interactions

TLE5 TLE1 TLE3

1.76e-04141163int:FOXQ1
InteractionSOX15 interactions

TLE5 TLE1 TLE3

1.76e-04141163int:SOX15
InteractionTLX2 interactions

TLE5 TLE1 TLE3

1.79e-04142163int:TLX2
InteractionNFIB interactions

TLE5 TLE1 TLE3

1.79e-04142163int:NFIB
InteractionGATA1 interactions

TLE5 TLE1 TLE3

3.10e-04171163int:GATA1
InteractionEGR2 interactions

TLE5 TLE1 TLE3

3.10e-04171163int:EGR2
InteractionTLX1 interactions

TLE5 TLE1 TLE3

3.32e-04175163int:TLX1
InteractionMSX1 interactions

TLE5 TLE1

3.66e-0436162int:MSX1
InteractionGATA3 interactions

TLE5 TLE1 TLE3

4.03e-04187163int:GATA3
InteractionATN1 interactions

TLE5 TLE1 TLE3

4.03e-04187163int:ATN1
InteractionNFIA interactions

TLE5 TLE1 TLE3

4.09e-04188163int:NFIA
InteractionHNF1B interactions

TLE5 TLE1 TLE3

4.22e-04190163int:HNF1B
InteractionMYOD1 interactions

TLE5 TLE1 TLE3

4.48e-04194163int:MYOD1
InteractionKLF5 interactions

TLE5 TLE1 TLE3

4.55e-04195163int:KLF5
InteractionFOXL1 interactions

TLE5 TLE1 TLE3

4.62e-04196163int:FOXL1
InteractionGATA2 interactions

TLE5 TLE1 TLE3

4.83e-04199163int:GATA2
InteractionFEV interactions

TLE5 TLE1 TLE3

5.12e-04203163int:FEV
InteractionPCDHB7 interactions

RETSAT LAMB1

5.48e-0444162int:PCDHB7
InteractionTLE1 interactions

TLE5 TLE1 TLE3

5.89e-04213163int:TLE1
InteractionSIX4 interactions

TLE1 TLE3

5.99e-0446162int:SIX4
InteractionPEX7 interactions

RETSAT TLE3

6.26e-0447162int:PEX7
InteractionERG interactions

TLE5 TLE1 TLE3

6.73e-04223163int:ERG
InteractionNFIX interactions

TLE5 TLE1 TLE3

7.09e-04227163int:NFIX
InteractionKLF3 interactions

TLE5 TLE1 TLE3

7.18e-04228163int:KLF3
InteractionFOXA3 interactions

TLE1 TLE3

7.66e-0452162int:FOXA3
InteractionNDRG1 interactions

KCNMA1 TLE3 COL10A1

7.84e-04235163int:NDRG1
InteractionTPRX2 interactions

TLE1 TLE3

8.88e-0456162int:TPRX2
InteractionHLA-DMB interactions

RETSAT ABCA2

9.19e-0457162int:HLA-DMB
InteractionZNF503 interactions

TLE5 TLE3

9.19e-0457162int:ZNF503
InteractionCRX interactions

TLE5 TLE1 TLE3

9.81e-04254163int:CRX
InteractionGMEB2 interactions

POLR1B TLE3

1.02e-0360162int:GMEB2
InteractionPROP1 interactions

TLE5 TLE1

1.02e-0360162int:PROP1
InteractionGCM1 interactions

TLE1 TLE3

1.31e-0368162int:GCM1
InteractionTBX3 interactions

TLE5 TLE3

1.34e-0369162int:TBX3
InteractionTLX3 interactions

TLE5 TLE1 TLE3

1.45e-03291163int:TLX3
InteractionC1QL4 interactions

COL10A1 CARNMT1

1.50e-0373162int:C1QL4
InteractionTCF4 interactions

TLE5 TLE1 TLE3

1.60e-03301163int:TCF4
InteractionSP7 interactions

TLE5 TLE1 TLE3

1.65e-03304163int:SP7
InteractionFGL1 interactions

TLE1 TLE3

1.67e-0377162int:FGL1
InteractionHNF1A interactions

TLE5 TLE1

1.80e-0380162int:HNF1A
InteractionSMG7 interactions

TLE5 TLE1 TLE3

1.89e-03319163int:SMG7
InteractionNKX2-5 interactions

TLE1 TLE3

1.89e-0382162int:NKX2-5
InteractionSOX7 interactions

TLE1 TLE3

1.89e-0382162int:SOX7
InteractionQPRT interactions

TLE1 TLE3

1.98e-0384162int:QPRT
InteractionIRF4 interactions

TLE5 TLE1

2.03e-0385162int:IRF4
InteractionLGALS1 interactions

KCNMA1 LAMB1 ABCA2

2.12e-03332163int:LGALS1
InteractionTGFA interactions

RETSAT ABCA2

2.13e-0387162int:TGFA
InteractionBRIP1 interactions

TLE3 CARNMT1

2.37e-0392162int:BRIP1
CytobandEnsembl 112 genes in cytogenetic band chr9q21

TLE1 CARNMT1

2.16e-03199162chr9q21
GeneFamilyCollagens

COL24A1 COL10A1

4.11e-0446122490
GeneFamilyWD repeat domain containing

TLE1 TLE3

1.25e-02262122362
CoexpressionGSE22886_NAIVE_VS_MEMORY_TCELL_UP

KCNMA1 TLE5 POLR1B TLE1

4.94e-06194164M4416
CoexpressionBHAT_ESR1_TARGETS_VIA_AKT1_DN

LAMB1 TLE1 EFNB2

1.60e-0582163M2235
CoexpressionNABA_CORE_MATRISOME

LAMB1 COL24A1 DPT COL10A1

1.82e-05270164MM17057
CoexpressionNABA_CORE_MATRISOME

LAMB1 COL24A1 DPT COL10A1

1.95e-05275164M5884
CoexpressionBHAT_ESR1_TARGETS_NOT_VIA_AKT1_DN

LAMB1 TLE1 EFNB2

1.98e-0588163M2232
CoexpressionWONG_ADULT_TISSUE_STEM_MODULE

KCNMA1 LAMB1 DPT TLE1 EFNB2

5.27e-05721165M1999
CoexpressionDODD_NASOPHARYNGEAL_CARCINOMA_UP

KCNMA1 LAMB1 POLR1B TLE1 COL10A1 EFNB2

1.19e-041407166M14427
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_AIRWAY_FIBROBLAST

DPT EFNB2

1.22e-0427162M45665
CoexpressionGSE6259_CD4_TCELL_VS_CD8_TCELL_UP

COL24A1 POLR1B EFNB2

1.87e-04187163M6738
CoexpressionHAN_JNK_SINGALING_UP

DPT EFNB2

2.05e-0435162M1596
CoexpressionHALLMARK_HEDGEHOG_SIGNALING

TLE1 TLE3

2.17e-0436162M5919
CoexpressionGSE12845_IGD_NEG_BLOOD_VS_DARKZONE_GC_TONSIL_BCELL_UP

RETSAT TLE5 TLE1

2.18e-04197163M3196
CoexpressionGSE13493_DP_VS_CD8POS_THYMOCYTE_DN

KCNMA1 POLR1B ABCA2

2.28e-04200163M3315
CoexpressionHAN_JNK_SINGALING_UP

DPT EFNB2

2.69e-0440162MM1183
CoexpressionNABA_COLLAGENS

COL24A1 COL10A1

3.11e-0443162MM17060
CoexpressionNABA_COLLAGENS

COL24A1 COL10A1

3.26e-0444162M3005
CoexpressionZHAN_MULTIPLE_MYELOMA_CD1_AND_CD2_DN

TLE3 CARNMT1

5.09e-0455162M16649
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RETSAT LAMB1 COL24A1 DPT

5.17e-07188164b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 COL24A1 DPT COL10A1

5.86e-071941648fae8061b350336299aa81f378e07deadbd55123
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 COL24A1 DPT COL10A1

5.86e-071941644d7d24390fdb379f943ddcc70a63f23955e10163
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 COL24A1 DPT COL10A1

6.61e-07200164251fd2923f108cd2086961d897244b392c32ad54
ToppCellcellseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMB1 COL24A1 DPT COL10A1

6.61e-07200164b441b3771fb7d9ee7b7a104afc35e466aace2da2
ToppCellRA-01._Fibroblast_I|RA / Chamber and Cluster_Paper

LAMB1 COL24A1 DPT

2.81e-051691636373562ab3b1765060212a6a53d6543e7e942e80
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RETSAT DPT TLE3

2.86e-05170163ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 DPT COL10A1

3.02e-0517316375e26a65071b0d2f30ed0b2aa9859c488f5cf362
ToppCell356C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 DPT COL10A1

3.02e-0517316326e2e674f5d312fa8f61c11b553dc6101f063b16
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 COL24A1 COL10A1

3.12e-051751631799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMB1 COL24A1 TLE1

3.17e-0517616307abf29d681abdd6c7cc87f9eaf9377e92ce212c
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|390C / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 DPT COL10A1

3.17e-05176163852d3da0907fe87c0ef23d75a63ce07619cf0c54
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|390C / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 DPT COL10A1

3.17e-05176163d2df1e435996c51213e88270af9f928e9e09a6f5
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMB1 COL24A1 TLE1

3.28e-051781635d6297f34e104bacefb25c4e2338b50fe13dd19a
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L2-4_RORB_GRIK1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMB1 COL24A1 TLE1

3.28e-05178163674ee5095b98929c29e4f6bd56029a336cc4a38c
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

3.39e-05180163935c091bbcd6d10b81dc4731779e5bd98205c99f
ToppCell5'-Airway_Nasal-Mesenchymal|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

3.39e-051801633dd384b7f3d9582b8fec9fe05100e466e6218b76
ToppCellfacs-Lung-24m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LAMB1 TRAPPC11 DPT

3.39e-05180163e9785ac2806103f725f5a5208495826354ec6e22
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 COL24A1 DPT

3.45e-05181163b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

3.57e-051831636d98973098c6d20c5305bce6a83a549a7d8dbfba
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L2-3_LINC00507_RPL9P17|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMB1 COL24A1 TLE1

3.57e-051831631645d4a55cd8c22d6eb47fc5c6b1e576c454f111
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

3.57e-05183163cc7f5a17b40e8d901885174922e5fa8877643071
ToppCell5'-Airway_Nasal-Mesenchymal-Fibroblastic-fibroblastic_type_2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

3.57e-05183163803376f5260de83c48d4f7301278d078a32b3e6e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMB1 COL24A1 TLE1

3.62e-0518416334e316ad8e7b8667cd8ad61397281802a252744f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DPT TLE1 EFNB2

3.68e-051851637dcdc009c5681ee05dd18968f7e85c3403fe34af
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

3.68e-0518516387c416d14ca6255bee39b16e7571553e36ee3069
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DPT TLE1 EFNB2

3.74e-051861634d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

LAMB1 COL24A1 DPT

3.80e-05187163bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

4.05e-051911630fae1c2ef9f83ac7721d0a9d69455bf97eed9257
ToppCellmetastatic_Lymph_Node-Fibroblasts-Myofibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

LAMB1 DPT COL10A1

4.05e-05191163aa43b472bc8362f79ae63f09f1ca764718bbf22c
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMB1 COL24A1 COL10A1

4.11e-0519216367e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(KCNN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LAMB1 COL24A1 DPT

4.11e-0519216320ede290e01ad574afd122d72b59dbc52c595fad
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

4.18e-05193163b05361ffe111a38cfa26eb86e4ae62c15ac99b7b
ToppCell10x3'2.3-week_17-19-Mesenchymal_osteo-stroma-osteoblast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

KCNMA1 COL24A1 DPT

4.24e-05194163811b382ec3da06a6bda7360abc8b633f96b2019e
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNMA1 DPT EFNB2

4.24e-051941637bf6edefd13047e04665dbe34051ef3f481f85a4
ToppCell10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

KCNMA1 COL24A1 DPT

4.24e-05194163292ce9021678534c9eedb367b9772a9d976208a8
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNMA1 DPT EFNB2

4.24e-05194163c992e3357f4bf3069f8d697803e5785e49a2ef0a
ToppCelldroplet-Lung-3m-Mesenchymal-myofibroblast-myofibroblast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

KCNMA1 DPT EFNB2

4.24e-0519416319e5beae2c1f8bf42cbe618e89810ce7b01a396c
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 DPT EFNB2

4.31e-051951633f64e2313ec79a6d5f4013a52722d071172f6c5d
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB1 DPT COL10A1

4.31e-051951631236dc60288c7dd91868e86e9174a2dacd3b11b3
ToppCelldroplet-Lung-immune-endo-depleted-3m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 DPT EFNB2

4.31e-051951637a5108335353ac160b684650c5da97d6f7f4dbcf
ToppCellmetastatic_Lymph_Node-Fibroblasts|metastatic_Lymph_Node / Location, Cell class and cell subclass

LAMB1 DPT COL10A1

4.37e-05196163275e153347caf94edc0c50021bbab49c8696fecb
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

COL24A1 DPT COL10A1

4.44e-0519716316758f181ef07c60aee63072e1da9572c5c85414
ToppCellCOPD-Stromal-Myofibroblast|World / Disease state, Lineage and Cell class

LAMB1 DPT COL10A1

4.44e-05197163d51f484b4e01ac64233950d0b97fa88825ea1dbb
ToppCell11.5-Airway-Mesenchymal-Mesenchyme_SERPINF1-high|Airway / Age, Tissue, Lineage and Cell class

DPT TLE1 EFNB2

4.44e-051971639a053a32ff9c3a85ef9a3382453acd619cc48546
ToppCell(5)_Fibroblasts-(5)_Fibroblast-B_(Myofibroblast)|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

COL24A1 DPT COL10A1

4.51e-05198163196257c4420ac801ed9fbb444f11718adb7560ae
ToppCelltumor_Lung-Fibroblasts-Myofibroblasts|tumor_Lung / Location, Cell class and cell subclass

LAMB1 DPT COL10A1

4.51e-0519816331f9181dab689aabe9c6182c2ef7de65ba3f0ff6
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 COL24A1 DPT

4.51e-05198163300d7cc56207d77168390fa1ffcbcf76767b1b80
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 COL24A1 DPT

4.57e-05199163e1f1950d6f840485e263b83dc81b98910be3ae7a
ToppCelldistal-mesenchymal-Myofibroblast-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMB1 COL24A1 DPT

4.57e-0519916379917b5225cb45b4a0ea937f79f1752346e4346e
ToppCelldistal-3-mesenchymal-Myofibroblast|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL24A1 DPT COL10A1

4.57e-051991631f20addc0d138fec02ed6ca4c518169c568de263
ToppCellmetastatic_Brain-Fibroblasts-FB-like_cells|metastatic_Brain / Location, Cell class and cell subclass

LAMB1 DPT COL10A1

4.57e-0519916312133087eae9f0e9b6c13a71e8187117768e64ce
ToppCellBiopsy_Control_(H.)-Mesenchymal-Myofibroblasts|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

LAMB1 DPT COL10A1

4.57e-051991637a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCellBronchial-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 DPT COL10A1

4.57e-0519916321335475bbfbad8a6943b8076a6c1c67f3eec5d3
ToppCellBiopsy_Other_PF-Mesenchymal-Myofibroblasts|Biopsy_Other_PF / Sample group, Lineage and Cell type

LAMB1 DPT COL10A1

4.64e-05200163e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMB1 DPT COL10A1

4.64e-05200163e663995fc44c340d878d66b278b7b5c2ff784301
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 DPT COL10A1

4.64e-05200163731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMB1 DPT COL10A1

4.64e-052001632cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3---L2-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMB1 COL24A1 TLE1

4.64e-052001639c89e91bb630cc306a820927a36ea6fb3d13e9d7
ToppCelldistal-mesenchymal-Myofibroblast-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL24A1 DPT COL10A1

4.64e-05200163069c8949b33ecfdb6da32992002d4060ff6082bc
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMB1 COL24A1 TLE1

4.64e-052001630f23e72649a274043bf23e0952a9b5707c516acf
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-3|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

LAMB1 DPT COL10A1

4.64e-052001638cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCellBronchus_Control_(B.)-Stromal-TX-Fibroblasts-1|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

LAMB1 DPT COL10A1

4.64e-0520016316a3685c41194a0a4a772e4eee372160263480e0
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3--|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMB1 COL24A1 TLE1

4.64e-0520016396b1d2e70fbbba744fd4356a70efcf356aca9abc
ToppCellParenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 DPT COL10A1

4.64e-05200163efdf7066b7dd43e35dbc0d2719b75f250cf54af2
ToppCell367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 DPT COL10A1

4.64e-05200163082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMB1 COL24A1 COL10A1

4.64e-0520016307641f476cb1a131c2a50258b88cc13bb38c8379
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-3|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LAMB1 COL24A1 COL10A1

4.64e-05200163343fa6ba1f52d816d2e41466f674ff8360aecd81
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_myofibroblast|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 DPT COL10A1

4.64e-0520016354806080b5e97859ee6a4a9b4f19e22021c218f5
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LAMB1 COL24A1 DPT

4.64e-05200163fb53be20392a8309a7393774c774a1b1aec6e676
ToppCell(5)_Fibroblast-B_(Myofibroblast)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMB1 DPT COL10A1

4.64e-052001639bbaa666d0f3b4782c1b4b95e0fa5fc1467842d8
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMB1 COL24A1 TLE1

4.64e-05200163ad6f1d4d7f5d7bab2ba2e4fff58c535290065c0e
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMB1 COL24A1 COL10A1

4.64e-05200163d0c00cdd52c2e001aec9b935f4e981ba77d0386a
ToppCellNeuronal-Excitatory-eA(LAMP5_LINC00507)-FREM3-|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMB1 COL24A1 TLE1

4.64e-052001638821574d17b55dfea3ca0204e6b4c0ca6b19588a
ToppCellBiopsy_IPF-Mesenchymal-Myofibroblasts|Biopsy_IPF / Sample group, Lineage and Cell type

LAMB1 DPT COL10A1

4.64e-05200163c2c6f687c49ba790174b27c7b8b084af30b34c86
ToppCelldistal-mesenchymal-Myofibroblast|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

COL24A1 DPT COL10A1

4.64e-0520016361854a459385cd9295be37157a8f81a2c227dff3
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Nts_(Subiculum)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

COL24A1 COL10A1

3.33e-0476162355a6793e2828728da62357bd2250735b0fd76b1
ToppCellHippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7-Slc17a6.Nxph3-Nts_(Subiculum)|Hippocampus / BrainAtlas - Mouse McCarroll V32

COL24A1 COL10A1

3.33e-04761622c304b41c04a567874126df25b15d8ee2ad2b6d9
ToppCelllymphoid-T_cell-pro-T_cell|lymphoid / Lineage, cell class and subclass

LAMB1 COL24A1

5.52e-04981624da11182885d5f2673e85bd9c5717939b0268427
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DPT COL10A1

8.40e-041211622ae870f822488799cd0ad85e7f72af64e33a867f
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LAMB1 DPT

9.10e-04126162f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LAMB1 DPT

9.10e-04126162fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LAMB1 DPT

9.10e-041261621ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LAMB1 DPT

9.10e-041261622de551d7a8765afec1da8852727c79fec90f45f8
ToppCellEntopeduncular-Endothelial-ENDOTHELIAL_TIP|Entopeduncular / BrainAtlas - Mouse McCarroll V32

LAMB1 DPT

9.10e-041261623d507f829882d043f633db2612b76936e2042445
ToppCellTCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Undifferentiated_Pleomorphic_Sarcoma-7|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9

COL24A1 COL10A1

9.24e-04127162c4809d8502f460370f824719d69b13b400a2b202
ToppCellLPS-antiTNF-Epithelial_alveolar-Mes-Like-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

COL24A1 ABCA2

9.39e-041281622cf0384240a4a663869cf6b27d954236f6214a9a
ToppCellBronchial_Biopsy-Mesenchymal-Fibroblasts|Mesenchymal / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMB1 DPT

9.53e-0412916213cd10ffdd8f1ef7721884e9efd2cf25f170f414
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 COL24A1

1.14e-031411624aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 COL24A1

1.14e-03141162e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNMA1 COL24A1

1.15e-03142162759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DPT EFNB2

1.17e-03143162ce045ec7c311a1797ae562bec114f9e90604d063
ToppCellControl-Plasmablast|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

KCNMA1 COL24A1

1.20e-03145162fe68582f5a15b9714cb84fa32ac880e13cb69895
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

COL24A1 CARNMT1

1.20e-0314516242dd36c1bc2c43cfea7196e89f901e4ea2a403c7
ToppCellIIH-CD8-proli_CD4|IIH / Condition, Cell_class and T cell subcluster

LAMB1 ABCA2

1.22e-031461627fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCell367C-Lymphocytic-NK_cells-NK_cell_E|367C / Donor, Lineage, Cell class and subclass (all cells)

COL24A1 TLE1

1.27e-03149162f18bddc84b064f3d57a1281d5172c404d87f25da
ToppCellnormal_Lung-Myeloid_cells-Undetermined|normal_Lung / Location, Cell class and cell subclass

KCNMA1 COL24A1

1.30e-0315116223b6cf9a36ad0e937f69c75921bddd305a9a526c
ToppCellsevere_COVID-19-MAIT|World / disease group, cell group and cell class (v2)

TLE1 ABCA2

1.35e-0315416265ec7f7ef05c589903c4c9fe3849478c325fdc61
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage_3|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMB1 DPT

1.37e-03155162e1a20e88b9c0eaf7ca7004acc0eda096d1588563
ToppCellChildren_(3_yrs)-Mesenchymal-chondrocyte|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMB1 COL24A1

1.41e-03157162f147e24f2ece82e1c54750868954d09b3c461804
DrugAC1L1C2F

KCNMA1 LAMB1 COL24A1 COL10A1

8.98e-07110164CID000001711
DrugNSC49633

TLE5 COL24A1 COL10A1

6.53e-0653163CID000023340
DrugSyrosingopine [84-36-6]; Down 200; 6uM; MCF7; HT_HG-U133A

LAMB1 POLR1B TLE3 EFNB2

7.91e-061901646213_DN
DrugTriprolidine hydrochloride [550-70-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A

RETSAT LAMB1 POLR1B TLE3

8.41e-061931647008_DN
DrugDiloxanide furoate [3736-81-0]; Up 200; 12.2uM; HL60; HT_HG-U133A

KCNMA1 LAMB1 TLE1 COL10A1

9.12e-061971643062_UP
DrugNialamide [51-12-7]; Up 200; 13.4uM; PC3; HT_HG-U133A

KCNMA1 DPT TLE1 COL10A1

9.30e-061981644525_UP
Drughyaluronan

KCNMA1 LAMB1 COL24A1 COL10A1

2.84e-05263164CID000024759
DrugALT-711

KCNMA1 LAMB1

9.65e-0521162CID000216304
DrugDMSe

TLE5 COL24A1 COL10A1

1.01e-04132163CID000020796
Drugkhellin

COL24A1 DPT COL10A1

2.17e-04171163CID000003828
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A

LAMB1 TLE1 TLE3

2.87e-041881636451_DN
DrugGK-101

COL24A1 COL10A1

2.88e-0436162CID000161853
DrugPF-00562151-00 [351320-12-2]; Down 200; 10uM; MCF7; HT_HG-U133A

TLE5 TLE3 EFNB2

2.96e-041901636912_DN
DrugPipenzolate bromide [125-51-9]; Up 200; 9.2uM; MCF7; HT_HG-U133A

LAMB1 TLE1 ABCA2

3.05e-041921633460_UP
DrugHydrocortisone base [50-23-7]; Up 200; 11uM; PC3; HT_HG-U133A

TLE1 COL10A1 EFNB2

3.05e-041921636684_UP
DrugAdamantamine fumarate [80789-67-9]; Down 200; 9.6uM; MCF7; HT_HG-U133A

LAMB1 TRAPPC11 ABCA2

3.14e-041941633280_DN
DrugOxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; PC3; HT_HG-U133A

PHOX2B TLE1 COL10A1

3.14e-041941632114_UP
Drugchlorpromazine hydrochloride; Up 200; 1uM; HL60; HT_HG-U133A

TLE1 COL10A1 EFNB2

3.19e-041951636176_UP
DrugFamprofazone [22881-35-2]; Up 200; 10.6uM; PC3; HT_HG-U133A

KCNMA1 TLE1 ABCA2

3.19e-041951634309_UP
DrugSulfaguanidine [57-67-0]; Up 200; 18.6uM; MCF7; HT_HG-U133A

LAMB1 TLE1 COL10A1

3.24e-041961631495_UP
DrugMetampicillin sodium salt [6489-61-8]; Up 200; 10.4uM; HL60; HG-U133A

TLE5 TLE1 ABCA2

3.24e-041961631440_UP
DrugParbendazole [14255-87-9]; Up 200; 16.2uM; PC3; HT_HG-U133A

TLE1 ABCA2 EFNB2

3.24e-041961634535_UP
DrugApramycin [37321-09-8]; Down 200; 7.4uM; HL60; HT_HG-U133A

TRAPPC11 TLE3 EFNB2

3.24e-041961632914_DN
DrugPaclitaxel [33069-62-4]; Up 200; 4.6uM; MCF7; HT_HG-U133A

TLE1 TLE3 ABCA2

3.24e-041961635320_UP
DrugPyrazinamide [ 98-96-4]; Up 200; 32.4uM; HL60; HT_HG-U133A

KCNMA1 COL10A1 EFNB2

3.24e-041961632478_UP
DrugZardaverine [101975-10-4]; Down 200; 15uM; MCF7; HT_HG-U133A

TLE5 LAMB1 ABCA2

3.29e-041971637347_DN
DrugTiletamine hydrochloride; Up 200; 15.4uM; MCF7; HT_HG-U133A

DPT TLE1 COL10A1

3.29e-041971636516_UP
DrugBendroflumethiazide [73-48-3]; Down 200; 9.4uM; MCF7; HT_HG-U133A

TRAPPC11 TLE3 ABCA2

3.29e-041971633415_DN
DrugFlunixin meglumine [42461-84-7]; Up 200; 8.2uM; HL60; HT_HG-U133A

KCNMA1 LAMB1 COL10A1

3.34e-041981632552_UP
DrugPargyline hydrochloride [306-07-0]; Down 200; 20.4uM; MCF7; HT_HG-U133A

LAMB1 TLE3 ABCA2

3.34e-041981637016_DN
DrugCortisone [53-06-5]; Up 200; 11uM; HL60; HT_HG-U133A

PHOX2B COL10A1 ABCA2

3.34e-041981632385_UP
DrugMetformin hydrochloride [1115-70-4]; Up 200; 24.2uM; MCF7; HT_HG-U133A

KCNMA1 LAMB1 ABCA2

3.34e-041981631694_UP
DrugDiphenylpyraline hydrochloride [132-18-3]; Up 200; 12.6uM; MCF7; HT_HG-U133A

PHOX2B KCNMA1 COL10A1

3.34e-041981634765_UP
Drug(R)-(+)-Atenolol [56715-13-0]; Up 200; 15uM; HL60; HT_HG-U133A

KCNMA1 COL10A1 ABCA2

3.34e-041981632496_UP
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; HL60; HT_HG-U133A

LAMB1 TLE1 COL10A1

3.34e-041981636178_UP
DrugProglumide [6620-60-6]; Up 200; 12uM; HL60; HT_HG-U133A

TLE3 ABCA2 EFNB2

3.39e-041991632363_UP
DrugCyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; PC3; HT_HG-U133A

RETSAT POLR1B TLE3

3.39e-041991636740_DN
DrugMeptazinol hydrochloride [59263-76-2]; Up 200; 14.8uM; PC3; HT_HG-U133A

DPT TLE1 COL10A1

3.39e-041991634188_UP
DrugStrophanthidin [66-28-4]; Down 200; 9.8uM; MCF7; HT_HG-U133A

LAMB1 POLR1B ABCA2

3.44e-042001637182_DN
DrugClorgyline hydrochloride [17780-75-5]; Up 200; 13uM; PC3; HT_HG-U133A

KCNMA1 COL10A1 ABCA2

3.44e-042001636659_UP
DrugEnilconazole [35554-44-0]; Up 200; 13.4uM; MCF7; HT_HG-U133A

TLE1 COL10A1 ABCA2

3.44e-042001636518_UP
Drugp-Nitrophenyl alpha-D-xyloside

TLE5 COL10A1

3.74e-0441162CID000082482
Drugfluvalinate

COL10A1 EFNB2

4.31e-0444162CID000050516
DrugMadecassol

COL24A1 COL10A1

4.71e-0446162CID000108062
DrugTMTU

DPT COL10A1

4.71e-0446162CID000017725
Diseasesevere acute respiratory syndrome, COVID-19

KCNMA1 COL24A1 DPT

1.37e-03447153EFO_0000694, MONDO_0100096
Diseasespine bone mineral density

KCNMA1 TLE1

1.64e-03119152EFO_0007701
Diseaseage at onset, Myopia

KCNMA1 COL10A1

2.58e-03150152EFO_0004847, HP_0000545
Diseaserefractive error, age at onset, Myopia

KCNMA1 COL10A1

4.23e-03193152EFO_0004847, HP_0000545, MONDO_0004892
Diseaseamino acid measurement

KCNMA1 LAMB1 COL24A1

4.47e-03678153EFO_0005134
DiseaseAutistic Disorder

KCNMA1 LAMB1

7.59e-03261152C0004352

Protein segments in the cluster

PeptideGeneStartEntry
YTVNDLSMMKYYYEC

CARNMT1

386

Q8N4J0
EMDMISYNYDYYIRG

DPT

156

Q07507
LDMMQIYDGKKYYIY

MAGEB5

156

Q9BZ81
KYYLEGVSNEMYTEY

KCNMA1

591

Q12791
DSKTVGQYEYYKVYM

EFNB2

66

P52799
GQYEYYKVYMVDKDQ

EFNB2

71

P52799
RMEIREKYYYAVYDM

LAMB1

251

P07942
GLMEMAYNEYINEYY

ABCA2

1956

Q9BZC7
TNYYVYYDTDMDQAM

RETSAT

406

Q6NUM9
VMYTYDEYTKGYLDQ

COL10A1

621

Q03692
DYYYYEDLNTMLEME

COL24A1

471

Q17RW2
YVMYYEMSYGLNIEM

TLE5

61

Q08117
YVMYYEMSYGLNIEM

TLE1

61

Q04724
MVQMGEEYYYAKDYT

TRAPPC11

456

Q7Z392
YVMYYEMSYGLNIEM

TLE3

61

Q04726
LVRPSMYDYYDMDNY

POLR1B

721

Q9H9Y6
MYDYYDMDNYPIGTN

POLR1B

726

Q9H9Y6
MYKMEYSYLNSSAYE

PHOX2B

1

Q99453