Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	MATN3 LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	1.42e-04	188	84	6	GO:0005201
GeneOntologyMolecularFunction	neuroligin family protein binding	NRXN3 NRXN1	1.73e-04	5	84	2	GO:0097109
GeneOntologyMolecularFunction	NADPH binding	CBR4 NDOR1 NOS1	1.74e-04	26	84	3	GO:0070402
GeneOntologyMolecularFunction	cell adhesion molecule binding	NRXN3 NRXN1 SPTBN2 EIF4G2 OBSCN CKAP5 LAMB2 TLN2 EPS8L1 LDHA	2.06e-04	599	84	10	GO:0050839
GeneOntologyMolecularFunction	structural molecule activity	NEFH EPPK1 MATN3 SPTBN2 OBSCN LAMA2 LAMA4 LAMB2 TLN2 LAMC2 RPS19 COL1A1	3.39e-04	891	84	12	GO:0005198
MousePheno	abnormal bone mineral density	EBF2 GHRH CBR4 SLC38A10 LIPE ITCH CLEC11A EIF4G2 TNRC6B LAMC2 NOS1 COL1A1	2.42e-05	652	62	12	MP:0010119
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	3.63e-07	4	85	3	PF14914
Domain	LRRC37_N	LRRC37A LRRC37A3 LRRC37A2	3.63e-07	4	85	3	IPR032754
Domain	LRRC37AB_C	LRRC37A LRRC37A3 LRRC37A2	3.63e-07	4	85	3	IPR029423
Domain	LRRC37	LRRC37A LRRC37A3 LRRC37A2	3.63e-07	4	85	3	PF15779
Domain	LRRC37A/B-like	LRRC37A LRRC37A3 LRRC37A2	3.63e-07	4	85	3	IPR015753
Domain	LAM_G_DOMAIN	FAT4 NRXN3 NRXN1 LAMA2 LAMA4	7.73e-07	38	85	5	PS50025
Domain	Laminin_G_2	FAT4 NRXN3 NRXN1 LAMA2 LAMA4	1.01e-06	40	85	5	PF02210
Domain	EGF	FAT4 FCGBP NRXN3 NRXN1 MATN3 LAMA2 LAMA4 LAMB2 LAMC2	1.22e-06	235	85	9	SM00181
Domain	LamG	FAT4 NRXN3 NRXN1 LAMA2 LAMA4	1.64e-06	44	85	5	SM00282
Domain	EGF-like_dom	FAT4 FCGBP NRXN3 NRXN1 MATN3 LAMA2 LAMA4 LAMB2 LAMC2	1.96e-06	249	85	9	IPR000742
Domain	Laminin_G	FAT4 NRXN3 NRXN1 LAMA2 LAMA4	6.57e-06	58	85	5	IPR001791
Domain	EGF_LAM_2	LAMA2 LAMA4 LAMB2 LAMC2	1.00e-05	30	85	4	PS50027
Domain	EGF_LAM_1	LAMA2 LAMA4 LAMB2 LAMC2	1.00e-05	30	85	4	PS01248
Domain	Laminin_EGF	LAMA2 LAMA4 LAMB2 LAMC2	1.88e-05	35	85	4	PF00053
Domain	EGF_Lam	LAMA2 LAMA4 LAMB2 LAMC2	1.88e-05	35	85	4	SM00180
Domain	SPIN-2	SPIN2A SPIN2B	2.05e-05	2	85	2	IPR029564
Domain	EGF-like_CS	FAT4 NRXN3 NRXN1 MATN3 LAMA2 LAMA4 LAMB2 LAMC2	2.48e-05	261	85	8	IPR013032
Domain	Laminin_EGF	LAMA2 LAMA4 LAMB2 LAMC2	2.62e-05	38	85	4	IPR002049
Domain	-	FAT4 NRXN3 NRXN1 LAMA2 LAMA4	7.28e-05	95	85	5	2.60.120.200
Domain	EGF_1	FAT4 NRXN3 NRXN1 LAMA2 LAMA4 LAMB2 LAMC2	1.62e-04	255	85	7	PS00022
Domain	Laminin_aI	LAMA2 LAMA4	2.03e-04	5	85	2	IPR009254
Domain	Laminin_I	LAMA2 LAMA4	2.03e-04	5	85	2	PF06008
Domain	Laminin_II	LAMA2 LAMA4	2.03e-04	5	85	2	PF06009
Domain	Laminin_domII	LAMA2 LAMA4	2.03e-04	5	85	2	IPR010307
Domain	Spin-Ssty	SPIN2A SPIN2B	2.03e-04	5	85	2	PF02513
Domain	SPIN/Ssty	SPIN2A SPIN2B	2.03e-04	5	85	2	IPR003671
Domain	EGF_2	FAT4 NRXN3 NRXN1 MATN3 LAMA2 LAMB2 LAMC2	2.06e-04	265	85	7	PS01186
Domain	FAD_binding_1	NDOR1 NOS1	3.03e-04	6	85	2	PF00667
Domain	FAD-binding_1	NDOR1 NOS1	3.03e-04	6	85	2	IPR003097
Domain	-	NDOR1 NOS1	3.03e-04	6	85	2	1.20.990.10
Domain	NADPH_Cyt_P450_Rdtase_dom3	NDOR1 NOS1	3.03e-04	6	85	2	IPR023173
Domain	Syndecan	NRXN3 NRXN1	4.24e-04	7	85	2	PF01034
Domain	Syndecan/Neurexin_dom	NRXN3 NRXN1	4.24e-04	7	85	2	IPR027789
Domain	FLAVODOXIN_LIKE	NDOR1 NOS1	5.63e-04	8	85	2	PS50902
Domain	Flavodoxin/NO_synth	NDOR1 NOS1	5.63e-04	8	85	2	IPR008254
Domain	LAMININ_IVA	LAMA2 LAMC2	5.63e-04	8	85	2	PS51115
Domain	Laminin_B	LAMA2 LAMC2	5.63e-04	8	85	2	PF00052
Domain	Flavdoxin-like	NDOR1 NOS1	5.63e-04	8	85	2	IPR001094
Domain	Flavodoxin_1	NDOR1 NOS1	5.63e-04	8	85	2	PF00258
Domain	LamB	LAMA2 LAMC2	5.63e-04	8	85	2	SM00281
Domain	Laminin_IV	LAMA2 LAMC2	5.63e-04	8	85	2	IPR000034
Domain	Flavoprotein-like_dom	NDOR1 NOS1	9.00e-04	10	85	2	IPR029039
Domain	Flavoprot_Pyr_Nucl_cyt_Rdtase	NDOR1 NOS1	9.00e-04	10	85	2	IPR001709
Domain	-	NDOR1 NOS1	9.00e-04	10	85	2	3.40.50.360
Domain	BAH	DNMT1 BAHCC1	1.10e-03	11	85	2	SM00439
Domain	BAH	DNMT1 BAHCC1	1.10e-03	11	85	2	PF01426
Domain	BAH	DNMT1 BAHCC1	1.10e-03	11	85	2	PS51038
Domain	PNMA	CCDC8 PNMA6A	1.10e-03	11	85	2	PF14893
Domain	BAH_dom	DNMT1 BAHCC1	1.10e-03	11	85	2	IPR001025
Domain	PNMA	CCDC8 PNMA6A	1.10e-03	11	85	2	IPR026523
Domain	OxRdtase_FAD/NAD-bd	NDOR1 NOS1	1.31e-03	12	85	2	IPR001433
Domain	NAD_binding_1	NDOR1 NOS1	1.31e-03	12	85	2	PF00175
Domain	Neurexin-like	NRXN3 NRXN1	1.80e-03	14	85	2	IPR003585
Domain	4.1m	NRXN3 NRXN1	1.80e-03	14	85	2	SM00294
Domain	Laminin_N	LAMA2 LAMB2	2.36e-03	16	85	2	IPR008211
Domain	LAMININ_NTER	LAMA2 LAMB2	2.36e-03	16	85	2	PS51117
Domain	Laminin_N	LAMA2 LAMB2	2.36e-03	16	85	2	PF00055
Domain	HSP70	HSPA6 HSPA7	2.36e-03	16	85	2	PF00012
Domain	LamNT	LAMA2 LAMB2	2.36e-03	16	85	2	SM00136
Domain	HSP70_2	HSPA6 HSPA7	2.66e-03	17	85	2	PS00329
Domain	HSP70_3	HSPA6 HSPA7	2.66e-03	17	85	2	PS01036
Domain	HSP70_1	HSPA6 HSPA7	2.66e-03	17	85	2	PS00297
Domain	Hsp_70_fam	HSPA6 HSPA7	2.99e-03	18	85	2	IPR013126
Domain	ConA-like_dom	FAT4 NRXN3 NRXN1 LAMA2 LAMA4	3.25e-03	219	85	5	IPR013320
Domain	Fd_Rdtase_FAD-bd	NDOR1 NOS1	3.33e-03	19	85	2	IPR017927
Domain	FAD_FR	NDOR1 NOS1	3.33e-03	19	85	2	PS51384
Domain	Riboflavin_synthase-like_b-brl	NDOR1 NOS1	3.33e-03	19	85	2	IPR017938
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	NRXN1 LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	7.26e-08	59	52	6	M27218
Pathway	REACTOME_MET_ACTIVATES_PTK2_SIGNALING	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	7.45e-08	30	52	5	M27772
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	3.80e-07	41	52	5	M27778
Pathway	REACTOME_LAMININ_INTERACTIONS	LAMA2 LAMA4 LAMB2 LAMC2	4.20e-06	30	52	4	M27216
Pathway	PID_INTEGRIN1_PATHWAY	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	4.23e-06	66	52	5	M18
Pathway	PID_INTEGRIN4_PATHWAY	LAMA2 LAMB2 LAMC2	7.65e-06	11	52	3	M158
Pathway	WP_FOCAL_ADHESION	LAMA2 LAMA4 LAMB2 TLN2 LAMC2 PTK6 COL1A1	7.85e-06	199	52	7	M39402
Pathway	REACTOME_ECM_PROTEOGLYCANS	MATN3 LAMA2 LAMA4 LAMB2 COL1A1	8.50e-06	76	52	5	M27219
Pathway	REACTOME_SIGNALING_BY_MET	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	1.03e-05	79	52	5	M27643
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	1.39e-05	84	52	5	M7098
Pathway	PID_A6B1_A6B4_INTEGRIN_PATHWAY	LAMA2 LAMA4 LAMB2 LAMC2	2.40e-05	46	52	4	M239
Pathway	WP_FOCAL_ADHESION	LAMA2 LAMA4 LAMB2 LAMC2 PTK6 COL1A1	6.17e-05	187	52	6	MM15913
Pathway	KEGG_FOCAL_ADHESION	LAMA2 LAMA4 LAMB2 TLN2 LAMC2 COL1A1	8.70e-05	199	52	6	M7253
Pathway	REACTOME_EXTRACELLULAR_MATRIX_ORGANIZATION	NRXN1 MATN3 LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	1.09e-04	300	52	7	M610
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTORSIGNALING	LIPE LAMA2 LAMA4 LAMB2 LAMC2 NOS1 COL1A1	1.13e-04	302	52	7	M39719
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	VGF ITCH LAMA2 LAMA4 LAMB2 LAMC2 PTK6 DNMT1 COL1A1	1.25e-04	532	52	9	M27870
Pathway	WP_INFLAMMATORY_RESPONSE_PATHWAY	LAMB2 LAMC2 COL1A1	1.79e-04	30	52	3	M39641
Pathway	WP_INFLAMMATORY_RESPONSE_PATHWAY	LAMB2 LAMC2 COL1A1	1.79e-04	30	52	3	MM15812
Pathway	WP_FOCAL_ADHESION_PI3KAKTMTOR_SIGNALING_PATHWAY	LIPE LAMA2 LAMA4 LAMB2 LAMC2 NOS1 COL1A1	1.82e-04	326	52	7	MM15917
Pathway	WP_ALPHA_6_BETA_4_SIGNALING	LAMA2 LAMB2 LAMC2	2.39e-04	33	52	3	M39503
Pathway	KEGG_SMALL_CELL_LUNG_CANCER	LAMA2 LAMA4 LAMB2 LAMC2	2.55e-04	84	52	4	M3228
Pathway	WP_CYTOSINE_METHYLATION	TET2 DNMT1	3.68e-04	8	52	2	M39348
Pathway	WP_SMALL_CELL_LUNG_CANCER	LAMA2 LAMA4 LAMB2 LAMC2	4.26e-04	96	52	4	M39834
Pathway	REACTOME_REGULATION_OF_INSULIN_LIKE_GROWTH_FACTOR_IGF_TRANSPORT_AND_UPTAKE_BY_INSULIN_LIKE_GROWTH_FACTOR_BINDING_PROTEINS_IGFBPS	VGF MATN3 LAMB2 MSLN	1.11e-03	124	52	4	M27285
Pathway	REACTOME_ANCHORING_FIBRIL_FORMATION	LAMC2 COL1A1	1.36e-03	15	52	2	M27161
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	8.17e-10	18	89	5	11311202
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMA2 LAMA4 LAMB2 LAMC2	8.31e-09	10	89	4	9034910
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA2 LAMA4 LAMB2 LAMC2	1.30e-08	11	89	4	23472759
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA2 LAMA4 LAMB2 LAMC2	1.30e-08	11	89	4	21524702
Pubmed	Laminin isoforms in development and disease.	LAMA2 LAMB2 LAMC2	1.62e-08	3	89	3	17426950
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMA2 LAMA4 LAMB2 LAMC2	1.95e-08	12	89	4	9396756
Pubmed	The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.	LAMA2 LAMA4 LAMB2 COL1A1	2.81e-08	13	89	4	36350252
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	TET2 VPS13D NRXN1 SPTBN2 CKAP5 MAGI3 BAHCC1	4.63e-08	130	89	7	12421765
Pubmed	Laminin alpha5 chain is required for intestinal smooth muscle development.	LAMA2 LAMA4 LAMB2 LAMC2	5.35e-08	15	89	4	12921739
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA2 LAMA4 LAMB2 LAMC2	5.35e-08	15	89	4	15895400
Pubmed	Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.	LRRC37A LRRC37A3 LRRC37A2	6.47e-08	4	89	3	22419166
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA2 LAMA4 LAMB2 LAMC2	7.12e-08	16	89	4	17601529
Pubmed	Isoform-specific GSK3A activity is negatively correlated with human sperm motility.	SUGP2 TTC16 LRRC37A2 RPS19 LDHA SBSN	1.41e-07	92	89	6	30824926
Pubmed	Properly formed but improperly localized synaptic specializations in the absence of laminin alpha4.	LAMA2 LAMA4 LAMB2	1.61e-07	5	89	3	11369940
Pubmed	Diamond Blackfan anemia is mediated by hyperactive Nemo-like kinase.	NDOR1 RPS19 COL1A1	1.61e-07	5	89	3	32620751
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMA2 LAMA4 LAMB2 LAMC2	1.88e-07	20	89	4	22911573
Pubmed	A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.	LAMA2 LAMA4 LAMB2	3.22e-07	6	89	3	18817539
Pubmed	A new nomenclature for the laminins.	LAMA4 LAMB2 LAMC2	5.63e-07	7	89	3	7921537
Pubmed	Laminin isoforms in fetal and adult human adrenal cortex.	LAMA2 LAMA4 LAMB2	5.63e-07	7	89	3	14557481
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	LAMA2 LAMA4 LAMB2 LAMC2	5.74e-07	26	89	4	24742657
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SLC38A10 B4GALNT4 NDOR1 EPPK1 SUGP2 ZNF516 OBSCN EHMT1 LAMB2 TLN2 MICAL3 LYST BAHCC1 COL1A1	8.18e-07	1105	89	14	35748872
Pubmed	Reduced Dnmt3a increases Gdf5 expression with suppressed satellite cell differentiation and impaired skeletal muscle regeneration.	EHMT1 DNMT1 COL1A1	8.99e-07	8	89	3	29146735
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	VGF NEFH ITCH NRXN1 SPTBN2 ZNF516 CKAP5 EHMT1 TNRC6B TLN2 NOS1 KIF11 DNMT1	1.05e-06	963	89	13	28671696
Pubmed	The extracellular-matrix protein matrilin 2 participates in peripheral nerve regeneration.	MATN3 LAMA2 LAMB2	1.35e-06	9	89	3	19295126
Pubmed	Evolutionary dynamism of the primate LRRC37 gene family.	LRRC37A LRRC37A3 LRRC37A2	1.92e-06	10	89	3	23064749
Pubmed	Trophoblast-specific expression and function of the integrin alpha 7 subunit in the peri-implantation mouse embryo.	LAMA2 LAMA4 LAMC2	1.92e-06	10	89	3	11784026
Pubmed	Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.	LAMA2 LAMA4 LAMB2 LAMC2	3.41e-06	40	89	4	27068110
Pubmed	Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.	LAMA2 LAMB2 LAMC2	3.50e-06	12	89	3	26794322
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	LAMA2 LAMA4 LAMB2 SOD3 COL1A1	5.24e-06	97	89	5	27559042
Pubmed	Neurexin-3 subsynaptic densities are spatially distinct from Neurexin-1 and essential for excitatory synapse nanoscale organization in the hippocampus.	NRXN3 NRXN1	6.48e-06	2	89	2	37543682
Pubmed	Neurexin I alpha is a major alpha-latrotoxin receptor that cooperates in alpha-latrotoxin action.	NRXN3 NRXN1	6.48e-06	2	89	2	9430716
Pubmed	Mouse germ cell-less as an essential component for nuclear integrity.	GMCL1 GMCL2	6.48e-06	2	89	2	12556490
Pubmed	Senescence-induced alterations of laminin chain expression modulate tumorigenicity of prostate cancer cells.	LAMA4 LAMB2	6.48e-06	2	89	2	19048114
Pubmed	Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH.	ITCH SPART	6.48e-06	2	89	2	38503285
Pubmed	Association of a polymorphism in the NRXN3 gene with the degree of smoking in schizophrenia: a preliminary study.	NRXN3 NRXN1	6.48e-06	2	89	2	19658047
Pubmed	Laminins alpha2 and alpha4 in pancreatic acinar basement membranes are required for basal receptor localization.	LAMA2 LAMA4	6.48e-06	2	89	2	14729866
Pubmed	Molecular cloning and genomic organization of mouse homologue of Drosophila germ cell-less and its expression in germ lineage cells.	GMCL1 GMCL2	6.48e-06	2	89	2	10448096
Pubmed	Altered Expression of Genes Encoding Cornulin and Repetin in Atopic Dermatitis.	RPTN CRNN	6.48e-06	2	89	2	28219068
Pubmed	The human heat-shock genes HSPA6 and HSPA7 are both expressed and localize to chromosome 1.	HSPA6 HSPA7	6.48e-06	2	89	2	1346391
Pubmed	Allelic contribution of Nrxn1α to autism-relevant behavioral phenotypes in mice.	NDOR1 NRXN1	6.48e-06	2	89	2	36848371
Pubmed	Coordinate control of axon defasciculation and myelination by laminin-2 and -8.	LAMA2 LAMA4	6.48e-06	2	89	2	15699217
Pubmed	Functional cloning of SPIN-2, a nuclear anti-apoptotic protein with roles in cell cycle progression.	SPIN2A SPIN2B	6.48e-06	2	89	2	12145692
Pubmed	Stage-specific expression of mouse germ cell-less-1 (mGCL-1), and multiple deformations during mgcl-1 deficient spermatogenesis leading to reduced fertility.	GMCL1 GMCL2	6.48e-06	2	89	2	15700541
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	NRXN3 LRRC37A NRXN1 LRRC37A3 SPART	7.73e-06	105	89	5	9628581
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	LAMA2 LAMA4 LAMB2	8.86e-06	16	89	3	17948866
Pubmed	MEF2C regulates cortical inhibitory and excitatory synapses and behaviors relevant to neurodevelopmental disorders.	NRXN3 NRXN1 NOS1	1.07e-05	17	89	3	27779093
Pubmed	Beta1-integrins are critical for cerebellar granule cell precursor proliferation.	LAMA2 LAMA4 LAMB2	1.07e-05	17	89	3	15056720
Pubmed	Conditional Knockout of Neurexins Alters the Contribution of Calcium Channel Subtypes to Presynaptic Ca2+ Influx.	NRXN3 NRXN1	1.94e-05	3	89	2	38891114
Pubmed	alpha-Neurexins are required for efficient transmitter release and synaptic homeostasis at the mouse neuromuscular junction.	NRXN3 NRXN1	1.94e-05	3	89	2	16406382
Pubmed	Stress modulates Ahi1-dependent nuclear localization of ten-eleven translocation protein 2.	TET2 NDOR1	1.94e-05	3	89	2	34218273
Pubmed	Mice with ribosomal protein S19 deficiency develop bone marrow failure and symptoms like patients with Diamond-Blackfan anemia.	RPS19 COL1A1	1.94e-05	3	89	2	21989989
Pubmed	Murine foetal liver supports limited detectable expansion of life-long haematopoietic progenitors.	NDOR1 COL1A1	1.94e-05	3	89	2	36202972
Pubmed	Alternative Splicing of Presynaptic Neurexins Differentially Controls Postsynaptic NMDA and AMPA Receptor Responses.	NRXN3 NRXN1	1.94e-05	3	89	2	31005376
Pubmed	Temporal multimodal single-cell profiling of native hematopoiesis illuminates altered differentiation trajectories with age.	FGD5 COL1A1	1.94e-05	3	89	2	36961818
Pubmed	Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging.	FGD5 COL1A1	1.94e-05	3	89	2	30561324
Pubmed	Developmental expression and cellular origin of the laminin alpha2, alpha4, and alpha5 chains in the intestine.	LAMA2 LAMA4	1.94e-05	3	89	2	10364433
Pubmed	Regulated Dynamic Trafficking of Neurexins Inside and Outside of Synaptic Terminals.	NRXN3 NRXN1	1.94e-05	3	89	2	26446217
Pubmed	Analysis of the human neurexin genes: alternative splicing and the generation of protein diversity.	NRXN3 NRXN1	1.94e-05	3	89	2	11944992
Pubmed	Alternative splicing of neurexins 1-3 is modulated by neuroinflammation in the prefrontal cortex of a murine model of multiple sclerosis.	NRXN3 NRXN1	1.94e-05	3	89	2	33058888
Pubmed	Important contribution of alpha-neurexins to Ca2+-triggered exocytosis of secretory granules.	NRXN3 NRXN1	1.94e-05	3	89	2	17035546
Pubmed	Spartin activates atrophin-1-interacting protein 4 (AIP4) E3 ubiquitin ligase and promotes ubiquitination of adipophilin on lipid droplets.	ITCH SPART	1.94e-05	3	89	2	20504295
Pubmed	Neurexins: three genes and 1001 products.	NRXN3 NRXN1	1.94e-05	3	89	2	9448462
Pubmed	Deletion of α-neurexin II results in autism-related behaviors in mice.	NRXN3 NRXN1	1.94e-05	3	89	2	25423136
Pubmed	The role of laminins in the organization and function of neuromuscular junctions.	LAMA4 LAMB2	1.94e-05	3	89	2	27614294
Pubmed	Endogenous β-neurexins on axons and within synapses show regulated dynamic behavior.	NRXN3 NRXN1	1.94e-05	3	89	2	34133920
Pubmed	D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice.	NDOR1 COL1A1	1.94e-05	3	89	2	24589777
Pubmed	Laminin α2, α4, and α5 Chains Positively Regulate Migration and Survival of Oligodendrocyte Precursor Cells.	LAMA2 LAMA4	1.94e-05	3	89	2	31882770
Pubmed	Transcription Factors Drive Tet2-Mediated Enhancer Demethylation to Reprogram Cell Fate.	TET2 COL1A1	1.94e-05	3	89	2	30220521
Pubmed	The within-subject application of diffusion tensor MRI and CLARITY reveals brain structural changes in Nrxn2 deletion mice.	NRXN3 NRXN1	1.94e-05	3	89	2	30858964
Pubmed	A doxycycline- and light-inducible Cre recombinase mouse model for optogenetic genome editing.	DNMT1 COL1A1	1.94e-05	3	89	2	36307419
Pubmed	Neurexins 1-3 Each Have a Distinct Pattern of Expression in the Early Developing Human Cerebral Cortex.	NRXN3 NRXN1	1.94e-05	3	89	2	28013231
Pubmed	Integration of a growth-suppressing BTB/POZ domain protein with the DP component of the E2F transcription factor.	GMCL1 GMCL2	1.94e-05	3	89	2	9878064
Pubmed	Ketamine Restores Thalamic-Prefrontal Cortex Functional Connectivity in a Mouse Model of Neurodevelopmental Disorder-Associated 2p16.3 Deletion.	NRXN3 NRXN1	1.94e-05	3	89	2	31812984
Pubmed	Structure and evolution of neurexin genes: insight into the mechanism of alternative splicing.	NRXN3 NRXN1	1.94e-05	3	89	2	12036300
Pubmed	β-Neurexins Control Neural Circuits by Regulating Synaptic Endocannabinoid Signaling.	NRXN3 NRXN1	1.94e-05	3	89	2	26213384
Pubmed	Neurexin gene family variants as risk factors for autism spectrum disorder.	NRXN3 NRXN1	1.94e-05	3	89	2	29045040
Pubmed	Structural and functional characterization of the IgSF21-neurexin2α complex and its related signaling pathways in the regulation of inhibitory synapse organization.	NRXN3 NRXN1	1.94e-05	3	89	2	38571813
Pubmed	Deletion of β-Neurexins in Mice Alters the Distribution of Dense-Core Vesicles in Presynapses of Hippocampal and Cerebellar Neurons.	NRXN3 NRXN1	1.94e-05	3	89	2	35173587
Pubmed	Epigenetic Regulation of Hepatic Lipid Metabolism by DNA Methylation.	TET2 DNMT1	1.94e-05	3	89	2	37282749
Pubmed	Decreased DNA methyltransferases expression is associated with coronary artery lesion formation in Kawasaki disease.	TET2 DNMT1	1.94e-05	3	89	2	31171909
Pubmed	Neurexins are differentially expressed in the embryonic nervous system of mice.	NRXN3 NRXN1	1.94e-05	3	89	2	7722633
Pubmed	Different roles for Tet1 and Tet2 proteins in reprogramming-mediated erasure of imprints induced by EGC fusion.	TET2 DNMT1	1.94e-05	3	89	2	23453809
Pubmed	The oncogenic microRNA miR-22 targets the TET2 tumor suppressor to promote hematopoietic stem cell self-renewal and transformation.	TET2 COL1A1	1.94e-05	3	89	2	23827711
Pubmed	Regeneration after blood loss and acute inflammation proceeds without contribution of primitive HSCs.	FGD5 COL1A1	1.94e-05	3	89	2	36787502
Pubmed	Schwann cell myelination requires integration of laminin activities.	NEFH LAMA2 LAMA4	2.08e-05	21	89	3	22767514
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	LAMA2 LAMA4 LAMB2 COL1A1	2.26e-05	64	89	4	22261194
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	2.61e-05	135	89	5	28675934
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	VPS13D EPPK1 LAMB2 RPS19 HSPA6 KIF11	3.25e-05	235	89	6	30258100
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	LAMA2 LAMA4 LAMB2 SOD3 COL1A1	3.80e-05	146	89	5	27068509
Pubmed	[DNA hypomethylation in villi of patients with unexplained recurrent spontaneous abortion and its mechanism].	TET2 DNMT1	3.87e-05	4	89	2	31167695
Pubmed	Deorphanizing FAM19A proteins as pan-neurexin ligands with an unusual biosynthetic binding mechanism.	NRXN3 NRXN1	3.87e-05	4	89	2	32706374
Pubmed	KLF4, DAPK1 and SPG20 promoter methylation is not affected by DNMT1 silencing and hypomethylating drugs in lymphoma cells.	SPART DNMT1	3.87e-05	4	89	2	34751409
Pubmed	Temporal dissection of Rai1 function reveals brain-derived neurotrophic factor as a potential therapeutic target for Smith-Magenis syndrome.	NDOR1 COL1A1	3.87e-05	4	89	2	34463714
Pubmed	Gene expression profiling identifies genes predictive of oral squamous cell carcinoma.	LAMC2 COL1A1	3.87e-05	4	89	2	18669583
Pubmed	Beta1 integrins control the formation of cell chains in the adult rostral migratory stream.	LAMA2 LAMA4	3.87e-05	4	89	2	17344408
Pubmed	Laminin gamma1 is critical for Schwann cell differentiation, axon myelination, and regeneration in the peripheral nerve.	NEFH LAMA2	3.87e-05	4	89	2	14638863
Pubmed	Developmental expression of nicein adhesion protein (laminin-5) subunits suggests multiple morphogenic roles.	LAMB2 LAMC2	3.87e-05	4	89	2	8081888
Pubmed	Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.	TET2 COL1A1	3.87e-05	4	89	2	28823558
Pubmed	UVB induces cutaneous squamous cell carcinoma progression by de novo ID4 methylation via methylation regulating enzymes.	TET2 DNMT1	3.87e-05	4	89	2	32574963
Pubmed	Microenvironmental CXCL12 deletion enhances Flt3-ITD acute myeloid leukemia stem cell response to therapy by reducing p38 MAPK signaling.	TET2 NDOR1	3.87e-05	4	89	2	36550214
Interaction	C18orf21 interactions	NEFH EPPK1 FCGBP SPTBN2 EPS8L1 TYMP SBSN	5.06e-06	156	87	7	int:C18orf21
Cytoband	Xp11.1	SPIN2A SPIN2B	2.22e-05	4	89	2	Xp11.1
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	TTYH1 CCDC8 LIPE FCGBP ZNF497 CLEC11A RPS19 EPS8L1 SBSN ADM5	1.07e-04	1192	89	10	chr19q13
GeneFamily	Laminin subunits	LAMA2 LAMA4 LAMB2 LAMC2	3.20e-08	12	53	4	626
GeneFamily	Tudor domain containing\|Spindlin family	SPIN2A SPIN2B	8.38e-05	5	53	2	1089
GeneFamily	EF-hand domain containing\|S100 fused type protein family	RPTN CRNN	1.75e-04	7	53	2	1350
GeneFamily	Heat shock 70kDa proteins	HSPA6 HSPA7	1.11e-03	17	53	2	583
Coexpression	NABA_BASEMENT_MEMBRANES	LAMA2 LAMA4 LAMB2 LAMC2	1.03e-05	40	89	4	M5887
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EBF2 FAT4 LAMA2 LAMA4 LAMB2 ABCA9 SOD3 COL1A1	6.61e-09	199	89	8	95d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell	NS-moderate-d_16-33-Epithelial-Squamous\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TTYH1 CNNM1 RPTN CRNN LAMA4 EPS8L1 SBSN	1.18e-07	192	89	7	103496f428f59683ac3ae6147682c07c30663724
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT4 CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.36e-07	196	89	7	e7bfd4fb400ae0c473131d0fa306c26be08a6d03
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT4 CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.36e-07	196	89	7	82fad623212d986a7fca3496faf3f8c8f5b83a11
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FAT4 CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.36e-07	196	89	7	85e5046f774537684e1443c0fc147d562b7068d0
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EBF2 FAT4 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.51e-07	199	89	7	fb580e9321ddf97c73b2e356cd82523db74a38a2
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-2,_SCARA5\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	EBF2 FAT4 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.56e-07	200	89	7	2022df85df94ab8cbb4e80e3fe9894c01051c5e0
ToppCell	Bronchus_Control_(B.)-Stromal-TX\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	EBF2 FAT4 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.56e-07	200	89	7	69b41f5fb370aa8840a9ad7919d03ef1e57d1b5b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EBF2 CLEC11A LAMA2 LAMA4 SPIN2B COL1A1	1.66e-06	180	89	6	64956a85c404a2ea7e4eaf6f95ebcc52c198b7cc
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.83e-06	183	89	6	5cfcd589a480e67654d3d94e71916f122150db10
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.83e-06	183	89	6	c3ea8d3b916ffcaca3156e0d77a952724554c4ab
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.83e-06	183	89	6	81003ddc24164959dd41bb12fcac72638789b8f2
ToppCell	droplet-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l1-41\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EBF2 VGF NRXN3 LAMA4 FGD5 COL1A1	1.83e-06	183	89	6	07ca2786e62eca9feecf5e54a11864a960f7641a
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.95e-06	185	89	6	3cd0686a14e734a0f243070ab939adcb4c454478
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal-stromal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.95e-06	185	89	6	00258f458cbf6d36449db95528a6b5038d731d2d
ToppCell	facs-Mammary_Gland-Mammary_Gland-3m-Mesenchymal\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	1.95e-06	185	89	6	a94694e226856bc5b168464f52d76004145717a5
ToppCell	droplet-Lung-30m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLEC11A LAMA2 LAMA4 LAMC2 SOD3 COL1A1	1.95e-06	185	89	6	355b03c7ea438681e11a2b872c798c9ea26e1486
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	CCDC8 ITCH RNF6 LRRC37A3 CEP250 LAMA4	2.14e-06	188	89	6	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RNF6 TTC16 ENTR1 CKAP5 LAMB2 SHQ1	2.35e-06	191	89	6	39ef8e1d7cc3ebb11717e8a55501515e3b72b177
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 CLEC11A LAMA2 SPART ABCA9 SOD3	2.42e-06	192	89	6	9479e9859140ba98abfe88414de0b28fc2bf43b7
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EBF2 LAMA2 LAMA4 SOD3 FOXL1 COL1A1	2.42e-06	192	89	6	ad48c941a3ddfd9a5146bafc2209da577bb50531
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 LAMA2 LAMA4 LAMB2 ABCA9 COL1A1	2.42e-06	192	89	6	beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCell	droplet-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CLEC11A LAMA2 LAMA4 SOD3 FOXL1 COL1A1	2.42e-06	192	89	6	1b228f0929b505de82a39bf64c837887b0e56701
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 CLEC11A LAMA2 SPART ABCA9 SOD3	2.42e-06	192	89	6	d7faa993f68e530ad55185505384ae155d36c222
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 LAMA2 LAMA4 TLN2 ABCA9 COL1A1	2.42e-06	192	89	6	e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell	droplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EBF2 CLEC11A LAMA2 SOD3 FOXL1 COL1A1	2.42e-06	192	89	6	f9fb24457999dc9e751a099d7f995543b9330ad4
ToppCell	PND03-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	EBF2 LAMA2 LAMA4 SOD3 FOXL1 COL1A1	2.42e-06	192	89	6	19b94f254d51b9bda3d9b7c6f85e27ecb58409c8
ToppCell	Mesenchymal-matrix_fibroblast_2_cell\|World / Lineage, Cell type, age group and donor	FAT4 LAMA2 LAMA4 TLN2 ABCA9 COL1A1	2.42e-06	192	89	6	a769158c49d2b208c4224d85e7ae68c85cc372ed
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF NEFH CNNM1 B4GALNT4 NRXN3 SPTBN2	2.49e-06	193	89	6	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLEC11A LAMA2 LAMA4 MSLN SOD3 COL1A1	2.49e-06	193	89	6	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 CLEC11A LAMA2 LAMB2 SOD3 COL1A1	2.49e-06	193	89	6	858a186804b36d45957238d3d3eed2768b961641
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC11A LAMA2 LAMA4 LAMB2 SOD3 COL1A1	2.49e-06	193	89	6	f95b95c58a6edb8a03dd15ae166f47f9f33d8bd6
ToppCell	droplet-Lung-immune-endo-depleted-3m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 CLEC11A LAMA2 LAMB2 SOD3 COL1A1	2.49e-06	193	89	6	7865e7ec0a288249540d4cba94ae01c93e1b617c
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT4 LAMA2 LAMA4 TLN2 ABCA9 COL1A1	2.49e-06	193	89	6	9ab47b360bee1d4f1092c2269e58acebe9584021
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF NEFH CNNM1 B4GALNT4 NRXN3 SPTBN2	2.49e-06	193	89	6	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF NEFH CNNM1 B4GALNT4 NRXN3 SPTBN2	2.49e-06	193	89	6	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	facs-MAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC11A LAMA2 LAMA4 LAMB2 SOD3 COL1A1	2.49e-06	193	89	6	85faf6c5ce4769615a4eca036e2ba307e176bb52
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CLEC11A LAMA2 LAMA4 MSLN SOD3 COL1A1	2.49e-06	193	89	6	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	2.49e-06	193	89	6	160691b671710be10220803d788c2c961c236af1
ToppCell	facs-MAT-Fat-3m-Mesenchymal\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLEC11A LAMA2 LAMA4 LAMB2 SOD3 COL1A1	2.49e-06	193	89	6	110a7d2ba7d066c2be38be98b643b76c520dd980
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CARMIL3 CLEC11A LAMA2 SOD3 FOXL1 COL1A1	2.57e-06	194	89	6	7826fe5eb254ac032de0d978f39585a40e0b3ee4
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 NRXN3 NRXN1 LAMA2 TLN2 SOD3	2.57e-06	194	89	6	415801a3dfacf05f2b603fb424df3d045190a812
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 NRXN3 NRXN1 LAMA2 TLN2 SOD3	2.57e-06	194	89	6	256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TTYH1 NRXN3 NRXN1 LAMA2 TLN2 SOD3	2.57e-06	194	89	6	7942bc83c1bdca687795b91aa232824d603f9b09
ToppCell	facs-Thymus-nan-3m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GMCL1 FAM107B EIF4G2 MAGI3 LYST KIF11	2.64e-06	195	89	6	79114b3c78cc15c413bb58f0673e7215b784a9b6
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT4 CLEC11A LAMA2 LAMA4 ABCA9 SBSN	2.81e-06	197	89	6	0dd71e399f253787fa546a7e90c5373180b89ffd
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EBF2 LAMA2 LAMA4 SPART ABCA9 COL1A1	2.81e-06	197	89	6	ab5d3ebc73bd7cfc64381d14b92878b370205186
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	EBF2 NRXN1 CLEC11A MATN3 LAMA4 COL1A1	2.89e-06	198	89	6	0c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCell	metastatic_Brain-Fibroblasts-FB-like_cells\|metastatic_Brain / Location, Cell class and cell subclass	CCDC8 CLEC11A LAMA2 LAMA4 ABCA9 COL1A1	2.97e-06	199	89	6	12133087eae9f0e9b6c13a71e8187117768e64ce
ToppCell	distal-1-mesenchymal-Myofibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CNNM1 CLEC11A TMEM253 LAMA2 FOXL1 COL1A1	2.97e-06	199	89	6	58c36f5a30c6862b7f5587a0b9bc31da99e43dd5
ToppCell	distal-mesenchymal-Myofibroblast-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CNNM1 CLEC11A TMEM253 LAMA2 FOXL1 COL1A1	2.97e-06	199	89	6	79917b5225cb45b4a0ea937f79f1752346e4346e
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	933b5b400e48a511ba0a056be1d33d3610b5f10d
ToppCell	Biopsy_IPF-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_IPF / Sample group, Lineage and Cell type	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	2c5626ea8fb4b702d4560117e53edf6cfcf1971e
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 LAMA2 LAMA4 TLN2 ABCA9 COL1A1	3.06e-06	200	89	6	ad3fdcef895400f929f2ae12ff9bd85fd46adb3a
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	c3d4ce70ab51d74c9fe2f5864e52a4a9d7570e10
ToppCell	normal_Lung-Fibroblasts\|normal_Lung / Location, Cell class and cell subclass	CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	803cf7f1382d07220249029cd220233232027689
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	137f8f9d255c66336d4f8b44b2e3f3de721f2bf0
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EBF2 FAT4 CCDC8 LAMA2 LAMA4 COL1A1	3.06e-06	200	89	6	64d2941689d7ca8af54f9ba21c5aeabf719084ef
ToppCell	Bronchial-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	b04831708fa20471a127b87e8db3728b6e729ce8
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic-Fibro_adventitial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	74ad0ae592252060ee294d7483327d765a6ba1dd
ToppCell	tumor_Lung-Fibroblasts\|tumor_Lung / Location, Cell class and cell subclass	CCDC8 CLEC11A LAMA2 LAMA4 SOD3 COL1A1	3.06e-06	200	89	6	073a68b5ce232203ffee86342cba2a00d907e119
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	25d3865aa2ced11a5ed40013e83b47d942fdf582
ToppCell	Tracheal-10x5prime-Stromal-Fibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	7ba292c30d915e66ebc8026fa76492cedf64700e
ToppCell	Tracheal-10x5prime-Stromal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	920e6036c0a9c0089d0d898673daf9dd9d7279fc
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	EBF2 FAT4 LAMA2 LAMA4 ABCA9 COL1A1	3.06e-06	200	89	6	0c25d56292b9e5fefa4521b72635449be1ffd6fe
ToppCell	5'-Adult-LargeIntestine-Mesenchymal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLEC11A LAMA2 LAMA4 ABCA9 SOD3 COL1A1	3.06e-06	200	89	6	5a87bb8eb1c6bd2fbc357e1528e15ba1c0051438
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EBF2 FAT4 CCDC8 LAMA2 LAMA4 COL1A1	3.06e-06	200	89	6	76f3043cb88071256ff661885fe5a82a54f5b733
ToppCell	Biopsy_Control_(H.)-Mesenchymal-PLIN2+_Fibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	EBF2 LAMA2 LAMA4 ABCA9 SBSN COL1A1	3.06e-06	200	89	6	cdaf462b1db29dab61038eeab5ddd3eef3386763
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NEFH FAM107B LDHA NOS1 DNMT1	1.74e-05	160	89	5	ec81814f3a475ba9bc049cb793bf93bc0b650d37
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-epithelial_cell_of_thymus\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHAD1 CCDC8 EPPK1 FCGBP LAMC2	1.85e-05	162	89	5	3dc39db0d5f6f3d7bcc312a6bce7aaeb914138d1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH1 B4GALNT4 NRXN3 NRXN1 LAMA4	1.85e-05	162	89	5	d28b2ea1d2c8f3c6a107991573471b6d0c49c4ae
ToppCell	facs-Thymus-Epithelium-3m-Epithelial\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHAD1 CCDC8 EPPK1 FCGBP LAMC2	1.85e-05	162	89	5	0a7138266054ea5954649c8b61ef93905d56b068
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH1 B4GALNT4 NRXN3 NRXN1 LAMA4	1.85e-05	162	89	5	5bbd7130d4dad9035e73a439dda568195c136f31
ToppCell	facs-Thymus-Epithelium-3m-Epithelial-TECs\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FHAD1 CCDC8 EPPK1 FCGBP LAMC2	1.85e-05	162	89	5	25323785dd33337bcefd05958a4a1a208a9ceb04
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural-neural_cell-Schwann_Cell_/_Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH1 B4GALNT4 NRXN3 NRXN1 LAMA4	1.85e-05	162	89	5	eed223e61c8162a2fe004ab4e09de5e037be7553
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Neural\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	TTYH1 B4GALNT4 NRXN3 NRXN1 LAMA4	1.85e-05	162	89	5	e35ddce830e20ebeac1a2c405293fc4a5323dd4a
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CLEC11A OBSCN LAMA4 FOXL1 COL1A1	1.96e-05	164	89	5	a764b79a127c8f360af0b79a1da64658badf0dfa
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l49\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	OBSCN LAMA2 SOD3 FOXL1 COL1A1	2.20e-05	168	89	5	d2b91f2adc95dcfa623f8d7ca2df1c6f884da988
ToppCell	NS-moderate-d_0-4-Epithelial-Squamous\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RPTN CRNN LAMA4 EPS8L1 SBSN	2.27e-05	169	89	5	4a5d023ffcf83312d29b1d215eb6b744ef1a0777
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 NRXN3 SPTBN2 FAM107B MAGI3	2.54e-05	173	89	5	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EBF2 NRXN3 LAMA2 MAGI3 N4BP3	2.68e-05	175	89	5	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-myofibroblast_-_mature_-_DCN\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	EBF2 CLEC11A LAMA2 SOD3 COL1A1	2.75e-05	176	89	5	08f94b78b27feeb113dbfadbfa7fe34d08b2809b
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF CNNM1 B4GALNT4 NRXN3 SPTBN2	2.91e-05	178	89	5	a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF CNNM1 B4GALNT4 NRXN3 SPTBN2	2.91e-05	178	89	5	1bddbc083c36657bd6910f7466126ab325e88176
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RPTN CRNN EPS8L1 SBSN PTK6	2.99e-05	179	89	5	2b5f8e109a67c7fc3ec2b83e8f1854160c99283a
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VGF CNNM1 B4GALNT4 NRXN3 SPTBN2	2.99e-05	179	89	5	a3922476f33d2e4137a12dbda21a1703dff79684
ToppCell	tumor_Lung-Fibroblasts-Undetermined\|tumor_Lung / Location, Cell class and cell subclass	ANKRD35 CLEC11A LAMA4 SOD3 COL1A1	3.15e-05	181	89	5	53bcab4d6df4a3255d81877ba22fb95d4492ce9f
ToppCell	RV\|World / Chamber and Cluster_Paper	OBSCN LAMA4 TNRC6B TLN2 MICAL3	3.15e-05	181	89	5	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Pericyte-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CLEC11A LAMA2 LAMA4 FOXL1 COL1A1	3.23e-05	182	89	5	fc4a5bf784705efe7965ce43ac23c2a8e602e90a
ToppCell	3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EBF2 LAMA2 ABCA9 SOD3 COL1A1	3.23e-05	182	89	5	d179b5deb07c20d49eb6c58d5a65904f8921de3a
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	EBF2 LRRC37A LAMA2 ABCA9 COL1A1	3.32e-05	183	89	5	06a68fa2be36448064f4668be24a5b85ad85c6e8
ToppCell	PSB-critical-LOC-Epithelial-Squamous\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TTYH1 RPTN CRNN EPS8L1 SBSN	3.32e-05	183	89	5	2cf798a2371c61322484ea16fdfae0acfa94f102
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	EBF2 NRXN3 SPTBN2 LAMA2 MAGI3	3.32e-05	183	89	5	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_4_(MMP1+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANKRD35 NDOR1 CLEC11A LAMA2 COL1A1	3.32e-05	183	89	5	269afec240a756eec3bbae5f30ec784281af3433
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 ANKRD35 LAMA2 LAMA4 COL1A1	3.40e-05	184	89	5	3bffadb0cb2e0d825bdb6cfc5d23f5436cbc3efd
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TTYH1 B4GALNT4 NRXN3 NRXN1 LAMA2	3.40e-05	184	89	5	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	droplet-Kidney-nan-21m-Mesenchymal\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 ANKRD35 LAMA2 LAMA4 COL1A1	3.49e-05	185	89	5	33cc0e9d8b54cb7408b51235f2a70e044ebae04d
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EBF2 CLEC11A LAMA2 LAMA4 COL1A1	3.49e-05	185	89	5	1b990e3089772be2b38c6d7ea0d1bf22461ae3ea
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-Stroma____fibroblast\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EBF2 ANKRD35 LAMA2 LAMA4 COL1A1	3.49e-05	185	89	5	9954fc85b183c1cc45c3c24e3dadc7984ee6f649
ToppCell	droplet-Skin\|droplet / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD35 NDOR1 EPPK1 FCGBP SBSN	3.49e-05	185	89	5	657fd191ed160f8620d57b33820ec7222806f289
Computational	Adhesion molecules.	LAMA2 LAMA4 LAMB2 LAMC2 MSLN COL1A1	4.53e-05	141	50	6	MODULE_122
Drug	AC1L1G72	LAMA2 LAMA4 LAMB2 LAMC2	6.73e-08	11	88	4	CID000003553
Drug	ALT-711	LAMA4 LAMB2 LAMC2 COL1A1	1.19e-06	21	88	4	CID000216304
Drug	AC1L1B58	LAMA2 LAMA4 LAMB2 LAMC2	4.60e-06	29	88	4	CID000001288
Drug	BM165	LAMA4 LAMB2 LAMC2	9.00e-06	11	88	3	CID003352881
Drug	Tetracycline hydrochloride [64-75-5]; Up 200; 8.4uM; PC3; HT_HG-U133A	VPS13D NDOR1 LIPE CLEC11A ZNF516 LAMA2 EPS8L1	1.11e-05	196	88	7	5757_UP
Drug	Gramine [87-52-5]; Up 200; 23uM; PC3; HT_HG-U133A	VGF VPS13D LIPE NRXN3 RNF6 MATN3 LAMA4	1.11e-05	196	88	7	3999_UP
Drug	Nitrendipine [39562-70-4]; Up 200; 11uM; MCF7; HT_HG-U133A	VPS13D NRXN3 RNF6 MATN3 EIF4G2 FOXL1 COL1A1	1.11e-05	196	88	7	6464_UP
Drug	Probenecid [57-66-9]; Down 200; 14uM; PC3; HT_HG-U133A	EBF2 VGF IFIH1 NRXN3 SPTBN2 LAMA4 TNRC6B	1.18e-05	198	88	7	4185_DN
Drug	Etoposide [33419-42-0]; Down 200; 6.8uM; PC3; HT_HG-U133A	FAT4 NRXN3 SPTBN2 LAMA4 MICAL3 NOS1 PTK6	1.18e-05	198	88	7	6681_DN
Drug	Cefuroxime sodium salt [56238-63-2]; Down 200; 9uM; MCF7; HT_HG-U133A	VPS13D CEP250 ZNF516 EHMT1 TLN2 LAMC2 N4BP3	1.22e-05	199	88	7	6088_DN
Drug	YIGSR	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	1.38e-05	79	88	5	CID000123977
Drug	Calcort	LAMA2 LAMA4 LAMB2 LAMC2	1.39e-05	38	88	4	CID000026709
Drug	Ikvav	LAMA4 LAMB2 LAMC2 COL1A1	1.39e-05	38	88	4	CID000131343
Drug	lithium indium	SPIN2A SPIN2B	1.48e-05	2	88	2	CID011116062
Drug	scandium phosphate	SPIN2A SPIN2B	1.48e-05	2	88	2	CID006365269
Drug	rubidium nitrate	SPIN2A SPIN2B	1.48e-05	2	88	2	CID000025731
Drug	2-[(1R,2R,3S,4R,5R,6S)-2-[(2R,5S)-3-[(3S,4S,5R,6S)-4,5-dihydroxy-3-(methylamino)-6-methylol-tetrahydropyran-2-yl]-4-formyl-4-hydroxy-5-methylol-tetrahydrofuran-2-yl]oxy-5-guanidino-3,4,6-trihydroxy-cyclohexyl]guanidine	LAMA2 LAMA4 LAMB2 LAMC2 COL1A1	1.76e-05	83	88	5	CID011968896
Drug	1,2-dimethylhydrazine	LAMA2 LAMA4 LAMB2 LAMC2 SOD3	2.09e-05	86	88	5	CID000001322
Drug	kalinin	LAMA2 LAMA4 LAMB2 LAMC2	6.11e-05	55	88	4	CID000032518
Drug	CC270	LAMA2 LAMA4 LAMB2 LAMC2	8.06e-05	59	88	4	CID006918852
Drug	Helveticoside [630-64-8]; Down 200; 7.4uM; PC3; HT_HG-U133A	IFIH1 VPS13D SPTBN2 TLN2 PTK6 BAHCC1	8.28e-05	185	88	6	4327_DN
Drug	LG 5	LAMA2 LAMA4 LAMB2 LAMC2	8.61e-05	60	88	4	CID011840957
Drug	diphenylketen	SPIN2A SPIN2B	8.82e-05	4	88	2	CID000013696
Drug	Apigenin [520-36-5]; Down 200; 14.8uM; MCF7; HT_HG-U133A	VGF CEP250 SPART TLN2 N4BP3 BAHCC1	9.31e-05	189	88	6	4401_DN
Drug	PEG-SOD	NOS1 SOD3 COL1A1	9.34e-05	23	88	3	CID003086673
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	CNNM1 RNF6 SUGP2 EHMT1 LYST BAHCC1	9.87e-05	191	88	6	5234_DN
Drug	Rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A	NRXN3 CLEC11A LAMA4 TLN2 N4BP3 PTK6	1.02e-04	192	88	6	5567_UP
Drug	quercetin	CBR4 LAMA2 LAMA4 LAMB2 LAMC2 LDHA NOS1 HSPA6 SOD3	1.03e-04	482	88	9	CID005280343
Drug	Metanephrine hydrochloride DL [881-95-8]; Down 200; 17.2uM; PC3; HT_HG-U133A	NRXN3 SUGP2 CLEC11A CEP250 LAMA4 PTK6	1.04e-04	193	88	6	6734_DN
Drug	Reidispongiolide C	NEFH GMCL1 GMCL2 LAMA4 LAMB2 LAMC2 PTK6	1.05e-04	279	88	7	CID005289285
Drug	Sikvav	LAMA4 LAMB2 LAMC2	1.06e-04	24	88	3	CID005487517
Drug	Decamethonium bromide [541-22-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A	VGF LAMA4 TNRC6B NOS1 PTK6 COL1A1	1.07e-04	194	88	6	4174_DN
Drug	Metaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; PC3; HT_HG-U133A	CNNM1 SUGP2 CEP250 SPTBN2 LAMA4 EPS8L1	1.07e-04	194	88	6	4248_DN
Drug	Alclometasone dipropionate [667634-13-2]; Up 200; 7.6uM; PC3; HT_HG-U133A	NDOR1 LIPE CLEC11A LAMA4 EPS8L1 PTK6	1.07e-04	194	88	6	5752_UP
Drug	Selegiline hydrochloride [14611-52-0]; Down 200; 17.8uM; MCF7; HT_HG-U133A	IFIH1 RNF6 SUGP2 MICAL3 EPS8L1 PTK6	1.11e-04	195	88	6	2826_DN
Drug	CP-690334-01 [459212-38-5]; Up 200; 10uM; PC3; HT_HG-U133A	LIPE RNF6 CLEC11A ZNF516 EIF4G2 COL1A1	1.11e-04	195	88	6	4558_UP
Drug	3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; MCF7; HT_HG-U133A	VPS13D CLEC11A MATN3 N4BP3 NOS1 PTK6	1.11e-04	195	88	6	7361_UP
Drug	Nialamide [51-12-7]; Down 200; 13.4uM; PC3; HT_HG-U133A	VPS13D CLEC11A MATN3 SPTBN2 LAMA2 LAMA4	1.14e-04	196	88	6	3790_DN
Drug	Sulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT_HG-U133A	VGF VPS13D CEP250 LAMB2 EPS8L1 PTK6	1.14e-04	196	88	6	5523_DN
Drug	Dehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A	VGF VPS13D NRXN3 SPTBN2 LAMA4 LAMC2	1.14e-04	196	88	6	6673_DN
Drug	Phentolamine hydrochloride [73-05-2]; Up 200; 12.6uM; PC3; HT_HG-U133A	VGF NDOR1 LAMA4 EPS8L1 NOS1 COL1A1	1.17e-04	197	88	6	4336_UP
Drug	Ribavirin [36791-04-5]; Down 200; 16.4uM; MCF7; HT_HG-U133A	CLEC11A CEP250 ZNF516 TNRC6B TLN2 NOS1	1.17e-04	197	88	6	6018_DN
Drug	Saquinavir mesylate [149845-06-7]; Down 200; 5.2uM; PC3; HT_HG-U133A	VPS13D EPPK1 MATN3 LAMA4 TNRC6B COL1A1	1.17e-04	197	88	6	5770_DN
Drug	Esculin Hydrate [531-75-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A	VPS13D EIF4G2 LAMA4 LAMC2 EPS8L1 SOD3	1.17e-04	197	88	6	5411_UP
Drug	Sulfacetamide sodic hydrate [6209-17-2]; Up 200; 15.8uM; MCF7; HT_HG-U133A	CLEC11A EIF4G2 EHMT1 TNRC6B LAMB2 BAHCC1	1.17e-04	197	88	6	1695_UP
Drug	Betonicine [515-25-3]; Down 200; 25.2uM; PC3; HT_HG-U133A	VGF VPS13D CLEC11A ZNF516 EIF4G2 COL1A1	1.20e-04	198	88	6	3745_DN
Drug	Betazole hydrochloride; Down 200; 27uM; MCF7; HT_HG-U133A	CNNM1 CEP250 SPART MICAL3 N4BP3 COL1A1	1.20e-04	198	88	6	5445_DN
Drug	alpha-estradiol; Down 200; 0.01uM; PC3; HT_HG-U133A	EPPK1 RNF6 CLEC11A LAMA4 EPS8L1 COL1A1	1.20e-04	198	88	6	4434_DN
Drug	CP-319743 [172078-87-4]; Up 200; 10uM; MCF7; HT_HG-U133A	NDOR1 RNF6 CEP250 LAMA4 LAMC2 LYST	1.24e-04	199	88	6	7532_UP
Drug	clozapine; Up 200; 10uM; PC3; HT_HG-U133A	CEP250 LAMA4 TLN2 NOS1 SOD3 COL1A1	1.24e-04	199	88	6	1229_UP
Drug	Mafenide hydrochloride [138-37-4]; Down 200; 18uM; MCF7; HT_HG-U133A	CLEC11A SPTBN2 LAMA4 SPART EPS8L1 N4BP3	1.24e-04	199	88	6	2287_DN
Drug	Ambroxol hydrochloride [23828-92-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A	VGF RNF6 EIF4G2 SPART PTK6 BAHCC1	1.27e-04	200	88	6	3238_DN
Drug	2-amino-4,6-dinitrotoluene	LAMB2 LAMC2 TYMP LDHA	1.57e-04	70	88	4	ctd:C035208
Drug	dysprosium	LAMA2 LAMA4 LAMB2 LAMC2	1.95e-04	74	88	4	CID000023912
Drug	A0395	LAMA4 LAMB2 LAMC2 COL1A1	2.05e-04	75	88	4	CID009906466
Disease	renovascular hypertension (biomarker_via_orthology)	EIF4G2 LAMA2 NOS1	2.09e-05	19	84	3	DOID:1591 (biomarker_via_orthology)
Disease	Aneuploidy	CKAP5 KIF11	7.96e-05	5	84	2	C0002938
Disease	Squamous cell carcinoma of esophagus	CCHCR1 FAT4 RNF6 TYMP	1.60e-04	95	84	4	C0279626
Disease	Esophageal carcinoma	RNF6 CRNN	1.67e-04	7	84	2	C0152018
Disease	Hereditary Diffuse Gastric Cancer	FAT4 FCGBP RPS19 TYMP MSLN DNMT1	1.93e-04	293	84	6	C1708349
Disease	Stomach Neoplasms	FAT4 FCGBP RPS19 TYMP MSLN DNMT1	2.08e-04	297	84	6	C0038356
Disease	Malignant neoplasm of stomach	FAT4 FCGBP RPS19 TYMP MSLN DNMT1	2.20e-04	300	84	6	C0024623
Disease	Chromosomal Instability	CKAP5 KIF11	2.22e-04	8	84	2	C1257806
Disease	common bile duct neoplasm (is_marker_for)	TYMP MSLN	2.22e-04	8	84	2	DOID:4608 (is_marker_for)
Disease	insulin sensitivity measurement, response to polyunsaturated fatty acid supplementation	TNRC6B TLN2	4.33e-04	11	84	2	EFO_0004471, EFO_0009131
Disease	opioid dependence	FAT4 NRXN3 SPTBN2 TLN2 COL1A1	5.91e-04	237	84	5	EFO_0005611
Disease	pancreatic ductal carcinoma (is_marker_for)	TYMP MSLN DNMT1	7.11e-04	61	84	3	DOID:3587 (is_marker_for)
Disease	glucose measurement	TET2 LRRC37A RNF6 LRRC37A3 ENTR1 KIF11	7.66e-04	380	84	6	EFO_0004468
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	HSPA6 HSPA7	1.06e-03	17	84	2	EFO_0021969
Disease	Carcinoma, Pancreatic Ductal	MSLN DNMT1	2.12e-03	24	84	2	C0887833
Disease	endometriosis (is_marker_for)	GHRH DNMT1	2.30e-03	25	84	2	DOID:289 (is_marker_for)
Disease	low affinity immunoglobulin gamma Fc region receptor II-b measurement	HSPA6 HSPA7	2.30e-03	25	84	2	EFO_0021970
Disease	breast carcinoma	EBF2 TET2 NRXN3 SPTBN2 TNRC6B LAMB2 MAGI3 BAHCC1 COL1A1	2.45e-03	1019	84	9	EFO_0000305
Disease	diet measurement, bilirubin measurement	EIF4G2 LAMA2	2.49e-03	26	84	2	EFO_0004570, EFO_0008111
Disease	caudate volume change measurement, age at assessment	NRXN3 NRXN1	2.68e-03	27	84	2	EFO_0008007, EFO_0021491

Protein segments in the cluster

Peptide	Gene	Start	Entry
AARGARRQAEAAAQQ	TTYH1	171	Q9H313
RVRSAEEKNGEGQQS	BAHCC1	1031	Q9P281
AQGDLDTAARRGQHQ	ADM5	16	C9JUS6
REVNGRLENGNQARS	DNMT1	101	P26358
QNIAIEVDAFGTRNG	ABCA9	936	Q8IUA7
GDRSRFQVNAQSGVI	FAT4	731	Q6V0I7
RNVGVVDANVAAQSG	EBF2	31	Q9HAK2
SGDLAAQAAEQERQA	ANKRD35	881	Q8N283
RATGEQQRTAAAELG	ANKRD24	861	Q8TF21
LAQQAQGARAGGSAR	GMCL1	16	Q96IK5
AGARQQEGESRLNLV	LDHA	96	P00338
AAENDANIAIVGNVR	NRXN1	276	P58400
EVGRQSIRREQGAQA	LRRC37A3	1181	O60309
QDGATTDANGRANAV	MICAL3	846	Q7RTP6
DQVNEVAARAQASGI	MATN3	201	O15232
RQARGEDQCLGGAQA	MAGEB17	16	A8MXT2
EAINGSGNAENRERH	MAGI3	246	Q5TCQ9
EVGRQSIRREQGAQA	LRRC37A2	1181	A6NM11
EVGRQSIRREQGAQA	LRRC37A	1181	A6NMS7
GAVDKRAREAGNINQ	KIF11	276	P52732
RSAGAQALQEQLGAV	CARMIL3	466	Q8ND23
AAVREFEQSVQGGSQ	FGD5	1016	Q6ZNL6
VRFTRNGGNATLQVD	NRXN3	1181	Q9Y4C0
ETAGSAQGRAQEAEQ	LAMB2	1686	P55268
GEQTGQDAERTNTRA	LAMA2	1661	P24043
DQDQQEAARAALQGG	MSLN	216	Q13421
AAENDANIAIVGNVR	NRXN1	1281	Q9ULB1
LNSGNANEAVNGVRE	EIF4G2	556	P78344
SAQGQDAAQSEEKRG	CRNN	466	Q9UBG3
GRVEILANDQGNRTT	HSPA7	26	P48741
RAAIQERVAQGQTGN	NDOR1	466	Q9UHB4
ATRVSLQGRGENNEL	NOS1	191	P29475
SEAVRRLQAEGNATG	PTK6	86	Q13882
RRLVVQQAGQAEAGE	OBSCN	1681	Q5VST9
DAGAGENRRVSGNNS	ITCH	226	Q96J02
EGEAAALRQQQAGRS	NEFH	126	P12036
GDRDNAVRNAALNTI	CKAP5	1376	Q14008
GEARARGEAQSQNQA	FHAD1	666	B1AJZ9
RGEAQSQNQATDGRE	FHAD1	671	B1AJZ9
NFQRENEALRCGQGA	ENTR1	361	Q96C92
ADGQVQVFRQGRDAV	FCGBP	956	Q9Y6R7
GNLRRTGQEVAQAQE	FAM107B	116	Q9H098
RDAAARQLAQAEQEG	CEP250	826	Q9BV73
ALSRVAQAAGQGVRQ	C17orf107	121	Q6ZR85
AQAAGQGVRQAGAAV	C17orf107	126	Q6ZR85
QGVRQAGAAVGASAR	C17orf107	131	Q6ZR85
RIAAAENNGNESGVR	IFIH1	151	Q9BYX4
RVNFLVNAAGINRDG	CBR4	76	Q8N4T8
GRAREQGEAERQQLS	CCHCR1	531	Q8TD31
DFGVRQNGERVNHVN	LYST	3311	Q99698
AAQGAAAVAVGQAAR	FOXL1	221	Q12952
QQAERALGSAAADAQ	LAMC2	991	Q13753
GRVEILANDQGNRTT	HSPA6	26	P17066
VNEELQARLAQGRSG	EPS8L1	601	Q8TE68
GAAVTDGNDRGNVLQ	BMP2KL	296	Q5H9B9
EAIADQREGAAGNQR	CCDC8	306	Q9H0W5
AVQGADNQRAQARAG	CCDC8	421	Q9H0W5
DNQRAQARAGQRAEA	CCDC8	426	Q9H0W5
VDNAAGQAGNEAGRF	SBSN	156	Q6UWP8
EQRDVERAGGNQAAS	SLC38A10	671	Q9HBR0
ERAGGNQAASQLEEA	SLC38A10	676	Q9HBR0
AQRQASAAQEAQEDG	EHMT1	1271	Q9H9B1
AQRLSGVFAGVREQA	LIPE	331	Q05469
AAERGDAQQRLGQSR	LAMA4	721	Q16363
QGQRDLDRIAGQVAA	RPS19	126	P39019
AGRRQAEATRQAAAQ	VGF	306	O15240
EDRLGNVTRGAVQNT	RNF165	246	Q6ZSG1
VRFTRNGGNATLQVD	NRXN3	176	Q9HDB5
LAQQEQGARARGSAR	GMCL2	16	Q8NEA9
QAQAQARAEAEAGSP	EPPK1	3031	P58107
QAQAQARAEAEAGSP	EPPK1	4096	P58107
GETQEAAAAARRQEQ	EPPK1	4756	P58107
QASRQSQRELGGQVD	RNF215	276	Q9Y6U7
QHREGSSQDRQAQGD	RNF6	531	Q9Y252
DGGVRRNTAIQESDA	SHQ1	506	Q6PI26
AQEAEGQQTRAAAGR	SPIN2A	6	Q99865
GADRVVANGDTANKV	MRI1	246	Q9BV20
QQGESNQERGARARL	GHRH	61	P01286
VRAQTQEGAGARAGA	PNMA6A	336	P0CW24
QEGAGARAGAQAVAR	PNMA6A	341	P0CW24
ARAQATQGGREGQAR	B4GALNT4	591	Q76KP1
GDTRDAVQALQEAQG	CLEC11A	151	Q9Y240
GSAAEQEQARRVQAV	CNNM1	261	Q9NRU3
QGSNEIEIRAEGNSR	COL1A1	1391	P02452
ASQADGARVLNGASQ	ZNF516	131	Q92618
RENQEGAANVNVRGE	SPART	636	Q8N0X7
GAANVNVRGEKDEQT	SPART	641	Q8N0X7
VQGNGVLNSRDAARH	UNC50	11	Q53HI1
AGDGQRQQATLGAAD	ZNF497	51	Q6ZNH5
IGQERVDSANALANG	SPTBN2	1746	O15020
GNQASVENGNAGRRL	SOD3	191	P08294
AQEAEGQQTRAAAGR	SPIN2B	6	Q9BPZ2
GSQVQARGRALNIVD	SUGP2	206	Q8IX01
ASTGANERVGQREQT	TMEM253	196	P0C7T8
GVRGSQAQAEDLSAQ	TLN2	971	Q9Y4G6
AQQARQDAGILAVQG	TTC16	251	Q8NEE8
GRTSQQERGQEGAQD	RPTN	96	Q6XPR3
QKANGERRNFGVSQE	TET2	116	Q6N021
GTQAQGAARVAAALD	TYMP	321	P19971
ENAGVNFVVSGREQA	TNRC6B	351	Q9UPQ9
GRQRAAIEGQTVRDQ	VPS13D	2001	Q5THJ4
RGSRAQAQAQDAELV	N4BP3	406	O15049