Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpropionyl-CoA carboxylase activity

PCCA PCCB

5.68e-0521512GO:0004658
GeneOntologyMolecularFunctionprocollagen glucosyltransferase activity

PLOD3 PLOD2

1.70e-0431512GO:0033823
GeneOntologyMolecularFunctionprocollagen-lysine 5-dioxygenase activity

PLOD3 PLOD2

1.70e-0431512GO:0008475
GeneOntologyMolecularFunctionpeptidyl-lysine 5-dioxygenase activity

PLOD3 PLOD2

3.37e-0441512GO:0070815
GeneOntologyBiologicalProcesshomophilic cell adhesion via plasma membrane adhesion molecules

DSG2 PECAM1 PCDHB10 PCDHB9 PTPRT CELSR2 CDH4 CDH9 PLXNB3

9.44e-061871509GO:0007156
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

DSG2 PECAM1 PCDHB10 PCDHB9 PTPRT MAPK14 CELSR2 PTPRS CDH4 CDH9 PLXNB3

1.89e-0531315011GO:0098742
GeneOntologyBiologicalProcesstelencephalon development

PLXNA3 KIF3A EFHC1 PTPRS KDM2B NCOA1 LRP6 SECISBP2 DIXDC1 HERC1 DNAH5

3.25e-0533215011GO:0021537
GeneOntologyBiologicalProcessendothelial cell-matrix adhesion

PECAM1 ADAMTS9 MMP12

4.36e-05101503GO:0090673
GeneOntologyBiologicalProcesshydroxylysine biosynthetic process

PLOD3 PLOD2

5.25e-0521502GO:0046947
GeneOntologyBiologicalProcesshydroxylysine metabolic process

PLOD3 PLOD2

5.25e-0521502GO:0046946
GeneOntologyBiologicalProcessbrain development

PLXNA3 APLP1 GRIN2D KIF3A EFHC1 STXBP3 CELSR2 PTPRS PITX3 KDM2B NCOA1 LRP6 SECISBP2 DIXDC1 GNAQ HERC1 DNAH5 KDM4B

5.40e-0585915018GO:0007420
GeneOntologyBiologicalProcessforebrain development

PLXNA3 APLP1 KIF3A EFHC1 PTPRS KDM2B NCOA1 LRP6 SECISBP2 DIXDC1 GNAQ HERC1 DNAH5

6.10e-0548915013GO:0030900
GeneOntologyBiologicalProcessregulation of axonogenesis

PLXNA3 CDKL3 TIAM2 PTPRS MACF1 DIXDC1 CDH4 PLXNB3

8.30e-051921508GO:0050770
GeneOntologyBiologicalProcesshead development

PLXNA3 APLP1 GRIN2D KIF3A EFHC1 STXBP3 CELSR2 PTPRS PITX3 KDM2B NCOA1 LRP6 SECISBP2 DIXDC1 GNAQ HERC1 DNAH5 KDM4B

1.27e-0491915018GO:0060322
GeneOntologyBiologicalProcesscellular response to monoamine stimulus

APLP1 GSK3A PRMT5 GNAQ GNAS

1.37e-04681505GO:0071868
GeneOntologyBiologicalProcesscellular response to catecholamine stimulus

APLP1 GSK3A PRMT5 GNAQ GNAS

1.37e-04681505GO:0071870
GeneOntologyBiologicalProcessnegative regulation of transferase activity

WARS1 SHB PTPRT GSK3A HEXIM2 LATS1 LRP6 SPRED1 GNAQ

1.79e-042731509GO:0051348
GeneOntologyBiologicalProcesspositive regulation of axonogenesis

PLXNA3 TIAM2 MACF1 DIXDC1 CDH4 PLXNB3

1.87e-041141506GO:0050772
GeneOntologyBiologicalProcessresponse to catecholamine

APLP1 GSK3A PRMT5 GNAQ GNAS

1.92e-04731505GO:0071869
GeneOntologyBiologicalProcessmRNA export from nucleus

SMG1 SUPT6H DDX39A NUP160 DDX39B

2.05e-04741505GO:0006406
GeneOntologyBiologicalProcessresponse to monoamine

APLP1 GSK3A PRMT5 GNAQ GNAS

2.05e-04741505GO:0071867
GeneOntologyBiologicalProcessnegative regulation of protein kinase activity

WARS1 SHB PTPRT HEXIM2 LATS1 LRP6 SPRED1 GNAQ

2.19e-042211508GO:0006469
GeneOntologyBiologicalProcessregulation of developmental growth

PLXNA3 CDKL3 GSK3A MAPK14 LATS1 PTPRS MACF1 C3 GNAS CDH4 DDX39B

2.65e-0442115011GO:0048638
GeneOntologyBiologicalProcessshort-chain fatty acid metabolic process

ACSM1 PCCA PCCB

2.84e-04181503GO:0046459
GeneOntologyBiologicalProcessG protein-coupled dopamine receptor signaling pathway

GSK3A PRMT5 GNAQ GNAS

2.91e-04441504GO:0007212
GeneOntologyBiologicalProcessnegative regulation of kinase activity

WARS1 SHB PTPRT HEXIM2 LATS1 LRP6 SPRED1 GNAQ

3.40e-042361508GO:0033673
GeneOntologyBiologicalProcessregulation of anatomical structure morphogenesis

STARD13 PLXNA3 WARS1 CDKL3 TIAM2 KIF3A TIE1 ADAMTS9 PTPRS CAPRIN2 LRP6 MACF1 SPRED1 C3 DIXDC1 PDCD10 CDH4 PLXNB3 BRWD1

3.61e-04109015019GO:0022603
DomainHEAT_REPEAT

CEP104 PDS5B SMG1 RANBP6 MROH2B MROH7

1.79e-05701466PS50077
DomainProcol_lys_dOase

PLOD3 PLOD2

1.81e-0431462IPR001006
DomainLYS_HYDROXYLASE

PLOD3 PLOD2

1.81e-0431462PS01325
DomainTFIID-31

TAF9B TAF9

1.81e-0431462IPR003162
DomainTFIID-31kDa

TAF9B TAF9

1.81e-0431462PF02291
DomainCadherin_CS

DSG2 PCDHB10 PCDHB9 CELSR2 CDH4 CDH9

2.15e-041091466IPR020894
Domain-

PLXNA3 IQGAP3 RASAL2

2.43e-041614631.10.506.10
DomainCADHERIN_1

DSG2 PCDHB10 PCDHB9 CELSR2 CDH4 CDH9

2.62e-041131466PS00232
DomainCadherin

DSG2 PCDHB10 PCDHB9 CELSR2 CDH4 CDH9

2.62e-041131466PF00028
DomainCADHERIN_2

DSG2 PCDHB10 PCDHB9 CELSR2 CDH4 CDH9

2.75e-041141466PS50268
Domain-

DSG2 PCDHB10 PCDHB9 CELSR2 CDH4 CDH9

2.75e-0411414662.60.40.60
DomainCA

DSG2 PCDHB10 PCDHB9 CELSR2 CDH4 CDH9

2.88e-041151466SM00112
DomainCadherin-like

DSG2 PCDHB10 PCDHB9 CELSR2 CDH4 CDH9

3.02e-041161466IPR015919
DomainCadherin

DSG2 PCDHB10 PCDHB9 CELSR2 CDH4 CDH9

3.31e-041181466IPR002126
DomainRasGAP_dom

PLXNA3 IQGAP3 RASAL2

3.50e-04181463IPR001936
DomainRho_GTPase_activation_prot

STARD13 PLXNA3 IQGAP3 PLXNB3 RASAL2

6.34e-04881465IPR008936
PathwayWP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS

SATB2 TEAD3 LATS1 PRMT5

1.14e-05181144M39825
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

GALNT10 LETMD1 SNX17 RANBP6 SLC47A2 GSK3A NUP205 FOCAD STXBP3 CELSR2 PTPRS PPA2 MACF1 GNAQ HERC1 PCCA PCCB DDX39B QSOX2 VTI1B

3.91e-0810611512033845483
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

SMG1 ABCF1 PLOD3 PRPF6 NUP205 GTF2H4 SUPT6H MED27 HECTD1 PLOD2 NUP160 DDX39B CDC23

7.36e-084401511334244565
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

LZTR1 PLOD3 WARS1 DSG2 DNAJC16 TRIM26 RANBP6 ANKRD50 NUP205 MAPK14 TMTC3 PTPRS C3 GNAS TAF9 HECTD1 NUP160 QSOX2

2.64e-079741511828675297
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CEP104 SMG1 SATB2 SNX17 ANKRD50 TIAM2 NUP205 SUPT6H CAPRIN2 KDM2B DIXDC1 BSN KDM4B

5.98e-075291511314621295
Pubmed

Differential and restricted expression of novel collagen VI chains in mouse.

COL6A3 COL6A6 PECAM1

7.97e-075151321477648
Pubmed

Systematic analysis of the protein interaction network for the human transcription machinery reveals the identity of the 7SK capping enzyme.

PLOD3 CENPC TRIM26 PRPF6 HEXIM2 GTF2H4 TAF9B SUPT6H PRMT5 TAF9 PLOD2

1.21e-063901511117643375
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

SMG1 COL6A3 SHB MYOM3 ANKRD50 DYSF KIF3A ADAMTS9 SUPT6H MACF1 SPRED1 RCOR3

1.98e-064971511223414517
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

PDS5B ABCF1 PLOD3 COL6A6 PCDHB9 PRPF6 DYSF TTC6 CAPN7 HERC1 KDM4B CDC23

1.98e-064971511236774506
Pubmed

POH1 contributes to hyperactivation of TGF-β signaling and facilitates hepatocellular carcinoma metastasis through deubiquitinating TGF-β receptors and caveolin-1.

PLXNA3 TMC2 STXBP3 SUPT6H PRMT5 HERC1 DDX39A DNAH5 DDX39B

3.73e-06277151930745168
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

PDS5B DSG2 DNAJC16 RANBP6 FASTKD5 GSK3A NUP205 STXBP3 TMTC3 LRP6 HECTD1 PLOD2 IQGAP3 QSOX2 CDC23 VTI1B

3.75e-069421511631073040
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

PDS5B ABCF1 WARS1 DSG2 FASTKD5 PRPF6 IDH3G NUP205 GUCY1B2 STXBP3 SUPT6H PRMT5 PPA2 GNAS BSN DNAH5 IQGAP3 NUP160 DDX39B RASAL2

3.93e-0614251512030948266
Pubmed

Generation of an integrated transcription map of the BRCA2 region on chromosome 13q12-q13.

STARD13 PDS5B N4BP2L1

4.42e-06815138812419
Pubmed

Murine and human cathepsin Z: cDNA-cloning, characterization of the genes and chromosomal localization.

PTPRT GNAS PLTP

4.42e-068151310760573
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 GALNT10 ABCF1 PLOD3 WARS1 DSG2 DNAJC16 RANBP6 PTGS1 TMTC3 CELSR2 PTPRS PRMT5 LRP6 HECTD1 PLOD2 QSOX2 MSLN

5.11e-0612011511835696571
Pubmed

Meta-analysis of genome-wide association studies identifies three new risk loci for atopic dermatitis.

KIF3A DDX39A DDX39B

6.61e-069151322197932
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

TRIM26 ITPRID2 GSK3A SUPT6H KDM2B SECISBP2 MACF1 GNAS BSN TAF9 MED27 CDC23

1.09e-055881511238580884
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

SMG1 ABCF1 PLOD3 FASTKD5 IDH3G GSK3A HEXIM2 ULK3 GTF2H4 MAPK14 LATS1 RTL1 CAPN7 PDCD10 CDC23

1.09e-059101511536736316
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

STARD13 ABCF1 WARS1 MTAP STXBP3 PRMT5 PPA2 MACF1 ZFHX3 GNAS DDX39A PCCA PCCB IQGAP3

1.24e-058071511430575818
Pubmed

Combinatorial CRISPR screen identifies fitness effects of gene paralogues.

SMG1 RANBP6 IDH3G PTPRS PPA2 DDX39A DDX39B

1.80e-05186151733637726
Pubmed

Nuclear localization of poly(A)+ mRNA following siRNA reduction of expression of the mammalian RNA helicases UAP56 and URH49.

DDX39A DDX39B

1.87e-052151216949217
Pubmed

Overview of mutations in the PCCA and PCCB genes causing propionic acidemia.

PCCA PCCB

1.87e-052151210502773
Pubmed

The crosstalk between p38 and Akt signaling pathways orchestrates EMT by regulating SATB2 expression in NSCLC cells.

SATB2 MAPK14

1.87e-052151228937318
Pubmed

Binding of the human cytomegalovirus (HCMV) tegument protein UL69 to UAP56/URH49 is not required for efficient replication of HCMV.

DDX39A DDX39B

1.87e-052151220610707
Pubmed

Rapid changes in shear stress induce dissociation of a G alpha(q/11)-platelet endothelial cell adhesion molecule-1 complex.

PECAM1 GNAQ

1.87e-052151219332487
Pubmed

Correction of the metabolic defect in propionic acidemia fibroblasts by microinjection of a full-length cDNA or RNA transcript encoding the propionyl-CoA carboxylase beta subunit.

PCCA PCCB

1.87e-05215128188292
Pubmed

Structural differences between the closely related RNA helicases, UAP56 and URH49, fashion distinct functional apo-complexes.

DDX39A DDX39B

1.87e-052151238225262
Pubmed

Mutation spectrum of the PCCA and PCCB genes in Japanese patients with propionic acidemia.

PCCA PCCB

1.87e-052151215059621
Pubmed

Isolation of cDNA clones coding for the alpha and beta chains of human propionyl-CoA carboxylase: chromosomal assignments and DNA polymorphisms associated with PCCA and PCCB genes.

PCCA PCCB

1.87e-05215123460076
Pubmed

Propionic acidemia: identification of twenty-four novel mutations in Europe and North America.

PCCA PCCB

1.87e-052151212559849
Pubmed

[Analysis of PCCA and PCCB gene mutations in patients with propionic acidemia].

PCCA PCCB

1.87e-052151225636094
Pubmed

In vivo functional analysis of the histone 3-like TAF9 and a TAF9-related factor, TAF9L.

TAF9B TAF9

1.87e-052151212837753
Pubmed

Propionic Acidemia

PCCA PCCB

1.87e-052151222593918
Pubmed

Functional Analysis of the PCCA and PCCB Gene Variants Predicted to Affect Splicing.

PCCA PCCB

1.87e-052151233923806
Pubmed

Effect of PCCB gene mutations on the heteromeric and homomeric assembly of propionyl-CoA carboxylase.

PCCA PCCB

1.87e-052151211749052
Pubmed

Parsing the roles of DExD-box proteins DDX39A and DDX39B in alternative RNA splicing.

DDX39A DDX39B

1.87e-052151238801080
Pubmed

Identification of 34 novel mutations in propionic acidemia: Functional characterization of missense variants and phenotype associations.

PCCA PCCB

1.87e-052151230274917
Pubmed

Phospholipid transfer protein maps to distal mouse chromosome 2.

GNAS PLTP

1.87e-05215128661063
Pubmed

Transcriptional perturbation of protein arginine methyltransferase-5 exhibits MTAP-selective oncosuppression.

MTAP PRMT5

1.87e-052151233795785
Pubmed

Terminal regions of UAP56 and URH49 are required for their distinct complex formation functioning to an essential role in mRNA processing and export.

DDX39A DDX39B

1.87e-052151238377942
Pubmed

The GSK3 kinase and LZTR1 protein regulate the stability of Ras family proteins and the proliferation of pancreatic cancer cells.

LZTR1 GSK3A

1.87e-052151235114566
Pubmed

Phospholipase Cδ1 suppresses cell migration and invasion of breast cancer cells by modulating KIF3A-mediated ERK1/2/β- catenin/MMP7 signalling.

KIF3A PLCD1

1.87e-052151228423710
Pubmed

Complete genomic structure of mouse lysyl hydroxylase 2 and lysyl hydroxylase 3/collagen glucosyltransferase.

PLOD3 PLOD2

1.87e-052151211334715
Pubmed

Palmitoylation is required for signaling functions and membrane attachment of Gq alpha and Gs alpha.

GNAQ GNAS

1.87e-05215128227063
Pubmed

Two frequent mutations associated with the classic form of propionic acidemia in Taiwan.

PCCA PCCB

1.87e-052151224863100
Pubmed

Isolation and characterization of propionyl-CoA carboxylase from normal human liver. Evidence for a protomeric tetramer of nonidentical subunits.

PCCA PCCB

1.87e-05215126765947
Pubmed

PRMT5 silencing selectively affects MTAP-deleted mesothelioma: In vitro evidence of a novel promising approach.

MTAP PRMT5

1.87e-052151232301278
Pubmed

New splicing mutations in propionic acidemia.

PCCA PCCB

1.87e-052151217051315
Pubmed

Seventeen Novel Mutations in PCCA and PCCB Genes in Indian Propionic Acidemia Patients, and Their Outcomes.

PCCA PCCB

1.87e-052151227227689
Pubmed

Crystal structure of the alpha(6)beta(6) holoenzyme of propionyl-coenzyme A carboxylase.

PCCA PCCB

1.87e-052151220725044
Pubmed

The closely related RNA helicases, UAP56 and URH49, preferentially form distinct mRNA export machineries and coordinately regulate mitotic progression.

DDX39A DDX39B

1.87e-052151220573985
Pubmed

Propionyl-CoA carboxylase - A review.

PCCA PCCB

1.87e-052151229033250
Pubmed

Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.

ABCF1 DNAJC16 TRIM26 RANBP6 TTC6 NUP205 MAPK14 MTAP TAF9B PRMT5 PPA2 GNAS HECTD1 PLOD2 PCCB NUP160 DDX39B CDC23

2.12e-0513351511829229926
Pubmed

Polymorphisms in C2, CFB and C3 are associated with progression to advanced age related macular degeneration associated with visual loss.

ABCA4 LRP6 C3

2.82e-0514151319015224
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

STARD13 PDS5B ABCA4 LZTR1 METRNL ANKS1B TEAD3 GSK3A PRMT5 CAPRIN2 MROH7 SECISBP2 ZNF778 HERC1 PLXNB3 RASAL2 KDM4B

3.02e-0512421511730973865
Pubmed

ZZW-115-dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents.

PDS5B ABCF1 PLOD3 DSG2 PRPF6 ITPRID2 NUP205 MACF1 GNAS DDX39A NUP160 DDX39B

3.37e-056601511232780723
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

ABCF1 PLOD3 DSG2 TRIM26 BTBD10 PRPF6 ITPRID2 XAB2 NUP205 GTF2H4 PRMT5 C3 GNAS IQGAP3 NUP160 DDX39B RASAL2

3.51e-0512571511736526897
Pubmed

The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.

LZTR1 WARS1 DSG2 DNAJC16 SNX17 SHB ITPRID2 LATS1 TMTC3 TAF9B SECISBP2 TAF9 DDX39A QSOX2 VTI1B

3.52e-0510071511534597346
Pubmed

Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.

DSG2 SHB ANKRD50 STXBP3 PTPRS SPRED1 GNAS RASAL2 VTI1B

4.29e-05377151938117590
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

PDS5B CENPC DSG2 PRPF6 XAB2 PRMT5 RCOR3 DIXDC1 GNAS PDCD10 DDX39A PLOD2 IQGAP3 NUP160 DDX39B CDC23

4.55e-0511551511620360068
Pubmed

Targeted deficiency or cytosolic truncation of the VE-cadherin gene in mice impairs VEGF-mediated endothelial survival and angiogenesis.

SMG1 PECAM1 TIE1

5.22e-0517151310428027
Pubmed

Role of the different isoforms of cyclooxygenase and nitric oxide synthase during gastric ulcer healing in cyclooxygenase-1 and -2 knockout mice.

PTGS1 PTPRS

5.60e-053151216373427
Pubmed

Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta.

PECAM1 RTL1

5.60e-053151218176565
Pubmed

Very large G protein-coupled receptor 1 regulates myelin-associated glycoprotein via Gαs/Gαq-mediated protein kinases A/C.

GNAQ GNAS

5.60e-053151224191038
Pubmed

Identification of G-proteins coupling to the vasoactive intestinal peptide receptor VPAC(1) using immunoaffinity chromatography: evidence for precoupling.

GNAQ GNAS

5.60e-053151211812005
Pubmed

β-Arrestin-1 directly interacts with Gαs and regulates its function.

GNAQ GNAS

5.60e-053151223353685
Pubmed

Targeting Histone Demethylases in MYC-Driven Neuroblastomas with Ciclopirox.

KDM2B KDM4B

5.60e-053151228684529
Pubmed

D1-like dopaminergic activation of phosphoinositide hydrolysis is independent of D1A dopamine receptors: evidence from D1A knockout mice.

GNAQ GNAS

5.60e-05315129016340
Pubmed

Characterization of cDNAs for mouse lysyl hydroxylase 1, 2 and 3, their phylogenetic analysis and tissue-specific expression in the mouse.

PLOD3 PLOD2

5.60e-053151210429951
Pubmed

Identification of amino acids important for the catalytic activity of the collagen glucosyltransferase associated with the multifunctional lysyl hydroxylase 3 (LH3).

PLOD3 PLOD2

5.60e-053151211896059
Pubmed

Characterization of three fragments that constitute the monomers of the human lysyl hydroxylase isoenzymes 1-3. The 30-kDa N-terminal fragment is not required for lysyl hydroxylase activity.

PLOD3 PLOD2

5.60e-053151211956192
Pubmed

Growth-regulated expression and G0-specific turnover of the mRNA that encodes URH49, a mammalian DExH/D box protein that is highly related to the mRNA export protein UAP56.

DDX39A DDX39B

5.60e-053151215047853
Pubmed

Lysyl hydroxylase 3 is a multifunctional protein possessing collagen glucosyltransferase activity.

PLOD3 PLOD2

5.60e-053151210934207
Pubmed

Regulation of G protein-coupled receptor activities by the platelet-endothelial cell adhesion molecule, PECAM-1.

PECAM1 GNAQ

5.60e-053151218672896
Pubmed

Primary structure, tissue distribution, and chromosomal localization of a novel isoform of lysyl hydroxylase (lysyl hydroxylase 3).

PLOD3 PLOD2

5.60e-05315129582318
Pubmed

Investigation of a functional requirement for isoprenylation by the human prostacyclin receptor.

GNAQ GNAS

5.60e-053151211895442
Pubmed

Genetic ablation of complement C3 attenuates muscle pathology in dysferlin-deficient mice.

DYSF C3

5.60e-053151221060153
Pubmed

The lysyl hydroxylase isoforms are widely expressed during mouse embryogenesis, but obtain tissue- and cell-specific patterns in the adult.

PLOD3 PLOD2

5.60e-053151216996725
Pubmed

DIX domain containing 1 (DIXDC1) modulates VEGFR2 level in vasculatures to regulate embryonic and postnatal retina angiogenesis.

PECAM1 DIXDC1

5.60e-053151235144597
Pubmed

Distinct roles of the receptor tyrosine kinases Tie-1 and Tie-2 in blood vessel formation.

PECAM1 TIE1

5.60e-05315127596437
Pubmed

Interaction of the TEK and TIE receptor tyrosine kinases during cardiovascular development.

PECAM1 TIE1

5.60e-053151210498691
Pubmed

The genes encoding mouse lysyl hydroxylase isoforms map to chromosomes 4,5, and 9.

PLOD3 PLOD2

5.60e-053151211130984
Pubmed

G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortins.

GNAQ GNAS

5.60e-053151226595811
Pubmed

Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis.

STXBP3 VTI1B

5.60e-053151221444687
Pubmed

Galphaq reduces cAMP production by decreasing Galphas protein abundance.

GNAQ GNAS

5.60e-053151218948082
Pubmed

Gqα/G11α deficiency in dorsomedial hypothalamus leads to obesity resulting from decreased energy expenditure and impaired sympathetic nerve activity.

GNAQ GNAS

5.60e-053151233166186
Pubmed

Gq and Gs signaling acting in synergy to control GLP-1 secretion.

GNAQ GNAS

5.60e-053151227908836
Pubmed

Structural Elements in the Gαs and Gαq C Termini That Mediate Selective G Protein-coupled Receptor (GPCR) Signaling.

GNAQ GNAS

5.60e-053151227330078
Pubmed

High glucose-induced complement component 3 up-regulation via RAGE-p38MAPK-NF-κB signalling in astrocytes: In vivo and in vitro studies.

MAPK14 C3

5.60e-053151230246940
Pubmed

Human TAFII31 protein is a transcriptional coactivator of the p53 protein.

TAF9B TAF9

5.60e-05315127761466
Pubmed

The RNA helicase DDX39B and its paralog DDX39A regulate androgen receptor splice variant AR-V7 generation.

DDX39A DDX39B

5.60e-053151228025139
Pubmed

Hcc-1 is a novel component of the nuclear matrix with growth inhibitory function.

DDX39A DDX39B

5.60e-053151215338056
Pubmed

Procollagen-lysine, 2-oxoglutarate 5-dioxygenases 1, 2, and 3 are potential prognostic indicators in patients with clear cell renal cell carcinoma.

PLOD3 PLOD2

5.60e-053151231446433
Pubmed

Phospholipase C-delta1 and -delta3 are essential in the trophoblast for placental development.

PECAM1 PLCD1

5.60e-053151216314520
Pubmed

A retinoic acid receptor RARα pool present in membrane lipid rafts forms complexes with G protein αQ to activate p38MAPK.

MAPK14 GNAQ

5.60e-053151222056876
Pubmed

Structures of the human cholecystokinin 1 (CCK1) receptor bound to Gs and Gq mimetic proteins provide insight into mechanisms of G protein selectivity.

GNAQ GNAS

5.60e-053151234086670
Pubmed

GNAS, GNAQ, and GNA11 alterations in patients with diverse cancers.

GNAQ GNAS

5.60e-053151230204251
Pubmed

Heterotrimeric G proteins in the control of parathyroid hormone actions.

GNAQ GNAS

5.60e-053151228363951
Pubmed

Interferon-induced antiviral protein MxA interacts with the cellular RNA helicases UAP56 and URH49.

DDX39A DDX39B

5.60e-053151221859714
Pubmed

Human brain synembryn interacts with Gsalpha and Gqalpha and is translocated to the plasma membrane in response to isoproterenol and carbachol.

GNAQ GNAS

5.60e-053151212652642
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

PDS5B ABCF1 WARS1 PRPF6 NUP205 TAF9 DDX39A DNAH5 IQGAP3 NUP160 DDX39B CDC23

6.25e-057041511229955894
Cytoband5q31

PCDHB10 PCDHB9 CDKL3 KIF3A CDC23

4.13e-0511515155q31
CoexpressionGSE17721_LPS_VS_POLYIC_0.5H_BMDC_UP

DOK5 LETMD1 METRNL ACSM1 FASTKD5 DYSF MTAP GNAQ HECTD1

2.40e-062001509M3796
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

SECISBP2L STARD13 PDS5B DOK5 SATB2 CENPC SHB MAPK14 MTAP STXBP3 NCOA1 MACF1 ZFHX3 GNAQ PCCA PLOD2 NUP160

8.68e-0685615017M4500
CoexpressionGSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP

CEP104 SMG1 CENPC TRIM26 NUP205 CELSR2 MACF1 HERC1

9.71e-061801508M8239
CoexpressionGSE360_LOW_DOSE_B_MALAYI_VS_M_TUBERCULOSIS_MAC_UP

PLOD3 PECAM1 PFKFB1 TEAD3 BSN PCCA PCCB KDM4B

2.01e-051991508M5266
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL6A3 GALNT10 COL6A6 ACSM1 ANKS1B MGP C3 ZFHX3

2.56e-0718715184ea486991f66c29728d127171a07b81404ec0b78
ToppCellLA-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL6A3 GALNT10 ACSM1 ANKS1B MGP PTPRS C3 ZFHX3

3.53e-071951518a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCellRV-02._Fibroblast_II|World / Chamber and Cluster_Paper

COL6A3 ACSM1 ANKS1B MGP PTPRS NCOA1 C3 ZFHX3

3.53e-071951518ce90b30dcdb56d4cd925cdb79fd9d7cefd998f48
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2D TIAM2 ULK3 CELSR2 CAPRIN2 DIXDC1 PLCD1

1.97e-061711517b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCellfacs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN2D TIAM2 ULK3 CELSR2 CAPRIN2 DIXDC1 PLCD1

1.97e-0617115179d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCellP03-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

COL6A3 PECAM1 CD93 MGP TIE1 MACF1 PLTP

2.30e-061751517282f09bbdfa70d93b3f66591dcfb84c5ee0268c7
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMC2 PECAM1 DYSF CD93 TIE1 ADAMTS9 RASAL2

3.32e-0618515170ab1be455f2cd883c9d1522ca78112c37833352e
ToppCellControl-Endothelial-Endothelial-Artery|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

GALNT10 PECAM1 ITPRID2 TIAM2 CD93 MGP TIE1

3.44e-0618615172d3a975d2bf92e18e3410dd413fc9f84831d82de
ToppCellLPS_only-Endothelial-Endothelial-Vein|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PECAM1 SHB CD93 MGP TIE1 ADAMTS9 PLTP

4.24e-06192151752acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCellRV-01._Fibroblast_I|RV / Chamber and Cluster_Paper

COL6A3 ACSM1 ANKS1B MGP PTPRS C3 ZFHX3

4.24e-061921517356160b113c3305a61ceeaff33ce3c9da0be2878
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

SMG1 COL6A3 CENPC ZC3H12D MACF1 HERC1 DDX39B

4.24e-06192151747646d7e4990be85072987f92bf18d52f8da752e
ToppCellfacs-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l27|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP RASAL2

4.24e-0619215175012cc3ec0766f06af447463413422b484446c43
ToppCellLV-01._Fibroblast_I|LV / Chamber and Cluster_Paper

COL6A3 ACSM1 ANKS1B MGP PTPRS C3 ZFHX3

4.39e-061931517dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCellRV-02._Fibroblast_II|RV / Chamber and Cluster_Paper

COL6A3 ACSM1 ANKS1B MGP PTPRS C3 ZFHX3

4.54e-06194151711c79a8c56ece42713b04b321982e41e239f07a5
ToppCelldistal-1-Hematologic-IGSF21+_Dendritic|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PTGS1 CD93 ZC3H12D MROH7 ZFHX3 MMP12 PLTP

4.54e-061941517f30c866e5f41ee79bdc6b6e08af962d62b199835
ToppCell3'-Parenchyma_lung-Endothelial-Blood_vessel_EC-capillary_endothelial_cell-EC_general_capillary-EC_general_capillary_L.2.0.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WARS1 PECAM1 DYSF CD93 MGP TIE1 ADAMTS9

5.02e-06197151715d1e0dffee8f5ba8cee37adfbfa0551a0cd5e15
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 FOCAD NCOA1 UBR3 GNAQ HERC1 PCCA

5.37e-06199151794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellkidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WARS1 PECAM1 DYSF CD93 MGP TIE1 RASAL2

5.37e-06199151714e09eaa2335d4503de50250eb4258dd5b85b304
ToppCellControl_saline-Endothelial-Endothelial-Artery|Control_saline / Treatment groups by lineage, cell group, cell type

PECAM1 APLP1 ITPRID2 TIAM2 MGP TIE1 PLTP

5.55e-06200151765b71f1e8da5c3750fcd0a2e66d9ef3125a3f78a
ToppCellMild/Remission-B_naive-13|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)

ACSM1 TEAD3 IGHD DIXDC1 GNAQ TTLL10

1.02e-0514515167827aef87f834cd0d19780417757c9386e19b22e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SATB2 ABCA13 ADAMTS9 C3 DNAH5 CDH9

2.06e-0516415161cb5fbd7050650047ad6f2ca792118e98d58d22b
ToppCellEndothelial-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

DOK5 ABCA4 MGP TIE1 ADAMTS9 PITX3

2.28e-0516715166a03d16165e0b003092c39972928981abd4a75aa
ToppCell11.5-Distal-Mesenchymal-Mesenchyme_SERPINF1-high|Distal / Age, Tissue, Lineage and Cell class

DOK5 APLP1 PTGS1 MGP C3 MSLN

2.78e-0517315166989c9cebcd81eccceac7e5a86152676ee959386
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DOK5 PECAM1 PCDHB10 DYSF CD93 TIE1

2.78e-05173151666488d01e03264fb193285470901c9c4182fbae8
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PECAM1 ITPRID2 GRIN2D DYSF CD93 TIE1

2.78e-051731516b0ff9808e38cb64a734ced498cd0546728746cd5
ToppCell5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-cycling_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KCTD19 PECAM1 DYSF CD93 TIE1 RASAL2

2.87e-05174151642735f6a8e5ec36dd3d35aceea6d37cf3eaa1871
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

PECAM1 FOCAD CD93 MGP TAF9B TIE1

3.16e-0517715161921226196b2ab7919d9f843e60d9f4bd9ec9c57
ToppCelldroplet-Spleen-nan-24m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLOD3 METRNL TIAM2 CD93 TIE1 C3

3.16e-0517715165f20a1a875d6f85ec07b097e6afdb07c2f8f88ff
ToppCellfacs-Lung-EPCAM-18m-Endothelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 CD93 IQCA1L TIE1 PLTP PRODH

3.16e-0517715162433924dcb085ebbe2545d476ebd7ee68e6092fb
ToppCelltumor_Lung-Endothelial_cells-EPCs|tumor_Lung / Location, Cell class and cell subclass

STARD13 PECAM1 ITPRID2 CD93 MGP TIE1

3.16e-051771516f8b152c09d56a97e8c0482fb1a3964c05f9dc8c5
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL6A6 TMTC3 RTL1 CAPN7 HERC1 BSN

3.26e-051781516fcbbcc44271515de1969b4732b6441c012693d5f
ToppCell5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOK5 WARS1 PECAM1 DYSF TIE1 ADAMTS9

3.37e-0517915169fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PECAM1 SHB DYSF CD93 TIE1 RASAL2

3.37e-0517915168f9e538c822940785130297712b75131812a4603
ToppCellLA-01._Fibroblast_I|LA / Chamber and Cluster_Paper

COL6A3 COL6A6 ACSM1 MGP PTPRS ZFHX3

3.37e-051791516dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCellfacs-Lung-EPCAM-18m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 CD93 IQCA1L TIE1 PLTP PRODH

3.48e-051801516082c6116e0bbba8d9a3a82d14af55bdc8990c8c0
ToppCellfacs-Lung-EPCAM-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 CD93 IQCA1L TIE1 PLTP PRODH

3.48e-05180151653043d764fad9ac33ee40e356e562e759931adef
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

PECAM1 DYSF CD93 CELSR2 TIE1 RASAL2

3.58e-0518115169cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

3.81e-051831516c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

3.81e-051831516c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCellMesenchymal_cells-Osteoblasts|Mesenchymal_cells / Lineage and Cell class

DOK5 SATB2 METRNL PTPRS PLCD1 PLOD2

3.81e-051831516d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

3.81e-05183151692eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

SATB2 ABCA13 MYOM3 ANKS1B SLC47A2 CDH9

3.93e-05184151651ed1ebfdef45149541917c66cbacad87072e51f
ToppCellLPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PECAM1 SHB DYSF CD93 TIE1 ADAMTS9

4.05e-051851516808d5e880069aff8866cd2c733b9fe568a37701f
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PECAM1 DYSF CD93 TIE1 ADAMTS9 RASAL2

4.05e-051851516a987dbf6adf533c5f8a0a8a465a6c8e67e0ffcc8
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSG2 ENO4 EFHC1 PLCD1 DNAH5 MSLN

4.17e-05186151629c79b5a29907d4f3f87ad2ca04840c0f15b7d4e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WARS1 PECAM1 DYSF CD93 TIE1 RASAL2

4.30e-05187151635c382c0aabd46906113e5db30ea24bb8e658899
ToppCell367C-Endothelial_cells-Endothelial-D|367C / Donor, Lineage, Cell class and subclass (all cells)

PECAM1 DYSF CD93 MGP TIE1 ADAMTS9

4.30e-0518715161342bc614bc4045263c2eb0a535a1dd6c64e7abe
ToppCell367C-Endothelial_cells-Endothelial-D-|367C / Donor, Lineage, Cell class and subclass (all cells)

PECAM1 DYSF CD93 MGP TIE1 ADAMTS9

4.30e-0518715167aa206262b14b9f2aaa99e59da38b96c3594d2c9
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

STARD13 WARS1 PECAM1 DYSF CD93 TIE1

4.30e-051871516fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PECAM1 DYSF CD93 TIE1 ADAMTS9 MROH2B

4.30e-05187151625efb82afe863a853ecdd781ad89026c993aaa67
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF CD93 MGP TIE1 SPRED1

4.43e-051881516da862ea3c74f42d0dbae38b09211a45c593d477e
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF CD93 MGP TIE1 SPRED1

4.43e-051881516b82a7667ef74a05e8bc744f6c090a7cc7b8efe32
ToppCellfacs-Pancreas-Endocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF CD93 MGP TIE1 SPRED1

4.43e-05188151619672d284fe89c9c3c7697514ca1f659329c34f4
ToppCellCOVID-19-Heart-EC_(POSTN)|COVID-19 / Disease (COVID-19 only), tissue and cell type

DOK5 PECAM1 PTGS1 CD93 MGP ADAMTS9

4.56e-0518915167346c1112e2e155dbd71b6dbc80e680fd262a691
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PECAM1 ITPRID2 TIAM2 CD93 MGP TIE1

4.56e-051891516c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCellLPS_only-Endothelial-Endothelial-Artery|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PECAM1 ITPRID2 CD93 CRACD MGP TIE1

4.56e-051891516b028466fcd36fdeceec752e55a24286a1cd62ae4
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

4.70e-0519015169d5242759546be0089981ef1877e4ed5f81face5
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

4.70e-051901516b7fc451e160e31dc898b122de844b501f587db67
ToppCellMonocytes-Tissue-resident_macrophages|World / Immune cells in Kidney/Urine in Lupus Nephritis

PTGS1 CD93 C3 ZFHX3 GNAQ RASAL2

4.70e-05190151607215e8f292cb54c670037aaf28393cddbe5548c
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL6A3 ACSM1 ANKS1B MGP C3 ZFHX3

4.70e-05190151612992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_systemic-EC_venous_systemic_L.2.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOK5 SHB CD93 MGP TIE1 ADAMTS9

4.70e-051901516a318d80dd5cc33d43048883b0e7844b5aa280aab
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

4.70e-05190151683cc851fb9f644b17a8ebf4d99a646003769a22f
ToppCellfacs-Pancreas-Exocrine-3m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

4.70e-0519015165f440d4b334d66d419c03bd828f7d93f16c1ce67
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TAF9B PLTP

4.84e-051911516471205494b91be69926dc8159376132bcea0d9b5
ToppCellRV-01._Fibroblast_I|World / Chamber and Cluster_Paper

COL6A3 ACSM1 ANKS1B PTPRS C3 ZFHX3

4.84e-05191151670c067c54084bfb02c29bab085f4defd477194fb
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

4.98e-051921516f4cd65e6c5b17bcabf45fe5b687246c72e7975f7
ToppCellfacs-Kidney-nan-18m-Endothelial-fenestrated_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF CD93 TIE1 ZFHX3 PLTP

4.98e-051921516777e386a17bba9ec450bb9d64d8a9ab98d9a63ff
ToppCellfacs-Kidney-nan-18m-Endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF CD93 TIE1 ZFHX3 PLTP

4.98e-05192151660a2409546525a40a5658e0f9d6a50c37f28bb96
ToppCellfacs-Thymus-Epithelium-24m-Endothelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF PTGS1 CD93 TIE1 ADAMTS9 PLTP

4.98e-05192151639afea574725ce0c67afdd79facdb34f819a828d
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF PTGS1 CD93 TIE1 ADAMTS9 PLTP

4.98e-051921516597db951b1fbc37db22134c3d27d3ec4ceaa85f7
ToppCellfacs-Thymus-Epithelium-24m-Endothelial-endothelial_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DYSF PTGS1 CD93 TIE1 ADAMTS9 PLTP

4.98e-051921516bc275a9eccb1c7a46fd58b15ca5acdd9f7495842
ToppCelldroplet-Pancreas-PANCREAS-30m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF PTGS1 CD93 TIE1 PLTP

4.98e-051921516bcd8876235be503186f119653b39476488c0fa15
ToppCellfacs-Kidney-nan-18m-Endothelial-Pecam____fenestrated_capillary_endothelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PECAM1 DYSF CD93 TIE1 ZFHX3 PLTP

4.98e-0519215160f9db6091b373334b9beabe0e5782bf2bc54690b
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL6A3 PCDHB10 TEAD3 ENO4 ADAMTS9 BSN

5.12e-051931516cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell3'-Distal_airway-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

WARS1 PECAM1 CD93 MGP TIE1 ADAMTS9

5.12e-0519315161e6e2d786511cc40241197368f5df20c20b882f3
ToppCellsevere-low-quality_cells|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SMG1 TMTC3 ZC3H12D MACF1 HERC1 BRWD1

5.12e-0519315169337bc93e3904c7fc7c93c328518bcd6453b1e8c
ToppCellFetal_29-31_weeks-Endothelial-capillary_endothelial_cell_(Cap1)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

STARD13 PECAM1 DYSF CD93 TIE1 ADAMTS9

5.12e-051931516ad2df9b77999780860141be6ec366afc0172a331
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL6A3 PCDHB10 TEAD3 ENO4 ADAMTS9 BSN

5.12e-0519315166ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PECAM1 CD93 MGP TIE1 ADAMTS9 PLTP

5.12e-0519315167261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCellCOVID-19-kidney-FLT1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

METRNL PECAM1 DYSF CD93 TIE1 ADAMTS9

5.12e-051931516479abb1cd2eb978b8a4fdb900069a6329fc8cade
ToppCell10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

COL6A3 PCDHB10 TEAD3 ENO4 ADAMTS9 BSN

5.12e-051931516e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell(5)_Epithelial_cells-(5)_Epi_basal|(5)_Epithelial_cells / Oesophagus cell shreds on cell class (v1) and cell subclass (v1)

PECAM1 CD93 MGP TIE1 ADAMTS9 MSLN

5.27e-051941516b887b2ff19b76bd93c67f9a24762efae816efd45
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PECAM1 DYSF CD93 TIE1 MACF1 RASAL2

5.27e-0519415160b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellLA-02._Fibroblast_II|LA / Chamber and Cluster_Paper

COL6A3 GALNT10 ACSM1 MGP PTPRS ZFHX3

5.27e-051941516234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Subpleural_fibroblasts-Subpleural_fibroblasts_L.2.1.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DOK5 COL6A3 ADAMTS9 C3 PLOD2 PLTP

5.43e-0519515160866aaf053762d1a021fcbccff058526078a99da
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

WARS1 PECAM1 CD93 TIE1 ADAMTS9 GNAQ

5.43e-051951516fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellLPS_only-Endothelial-Endothelial-Activated_Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PECAM1 SHB DYSF CD93 TIE1 ADAMTS9

5.43e-05195151656efeb58df19f357d7d5ce87348d4f196a595421
ToppCellCOVID-19-Heart-EC_1|Heart / Disease (COVID-19 only), tissue and cell type

WARS1 PECAM1 CD93 TIE1 ADAMTS9 GNAQ

5.43e-05195151650a193475db1bb1e05b8590225a553688c372c14
ToppCell343B-Endothelial_cells-Endothelial-D|343B / Donor, Lineage, Cell class and subclass (all cells)

PECAM1 CD93 MGP TIE1 ADAMTS9 KCTD15

5.58e-05196151699953fe0a40e242f6945150345fc0a08ed95f8f9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WARS1 PECAM1 DYSF CD93 TIE1 ADAMTS9

5.58e-0519615167cbb19108b4553ef60ef5c230a29de1662c02efe
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WARS1 PECAM1 DYSF CD93 TIE1 ADAMTS9

5.58e-0519615164cd1e6b7a791e11a40b19f971b7011bd11fe6273
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

WARS1 PECAM1 DYSF CD93 TIE1 ADAMTS9

5.58e-051961516d37f714d4fb57e958f3738fdda085560813e5bb5
ToppCell343B-Endothelial_cells-Endothelial-D-|343B / Donor, Lineage, Cell class and subclass (all cells)

PECAM1 CD93 MGP TIE1 ADAMTS9 KCTD15

5.58e-0519615165edffdc4c1ff35d9ee0e5c1bed0dc0c90b76ea00
ToppCellParenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MYOM3 APLP1 CD93 MGP TIE1 ADAMTS9

5.74e-051971516ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCelltumor_Lung-Endothelial_cells|tumor_Lung / Location, Cell class and cell subclass

PECAM1 DYSF CD93 MGP TIE1 ADAMTS9

5.74e-0519715166870b311c54a73723768276a58456620f5217d43
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WARS1 PECAM1 DYSF CD93 TIE1 RASAL2

5.74e-051971516cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

WARS1 PECAM1 DYSF CD93 TIE1 RASAL2

5.74e-0519715160f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

WARS1 PECAM1 CD93 TIE1 ADAMTS9 RASAL2

5.74e-051971516ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

WARS1 PECAM1 DYSF CD93 TIE1 RASAL2

5.74e-051971516412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell343B-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DOK5 METRNL PTGS1 ADAMTS9 PPA2 GNAQ

5.74e-051971516ec92d60f802c9d4bdf9877bed5c0a91a5a5ed5d0
DrugNabumetone [42924-53-8]; Down 200; 17.6uM; HL60; HT_HG-U133A

LZTR1 SHB GSK3A XAB2 LRP6 ZFHX3 PLCD1 PLOD2 PLTP SENP5

6.98e-07195150103108_DN
Diseaseamino acid metabolic disorder (is_implicated_in)

PCCA PCCB PRODH

1.94e-05111473DOID:9252 (is_implicated_in)
Diseasepropionic acidemia (is_implicated_in)

PCCA PCCB

2.47e-0521472DOID:14701 (is_implicated_in)
DiseasePropionicaciduria

PCCA PCCB

2.47e-0521472C2717876
DiseasePROPIONIC ACIDEMIA

PCCA PCCB

2.47e-0521472606054
DiseasePropionic acidemia

PCCA PCCB

2.47e-0521472cv:C0268579
DiseaseCafe-au-Lait Spots

SPRED1 GNAS

7.37e-0531472C0221263
DiseasePropionic acidemia

PCCA PCCB

7.37e-0531472C0268579
Diseasefree cholesterol in very small VLDL measurement

N4BP2L1 CELSR2 PCCB PLTP

8.93e-05471474EFO_0022275
DiseaseSchizophrenia

ABCA13 MCHR2 ACSM1 FASTKD5 GRIN2D CSMD2 PTGS1 GSK3A MAPK14 PITX3 KDM2B DIXDC1 GNAS PRODH

1.40e-0488314714C0036341
DiseaseInsulin Resistance

METRNL C3 GNAS PLTP

2.32e-04601474C0021655
DiseaseInsulin Sensitivity

METRNL C3 GNAS PLTP

2.32e-04601474C0920563
Diseasefatty acid measurement

ABCA4 SNX17 CELSR2 MACF1 PLOD2 PCCB PLTP PRODH BRWD1

3.54e-044361479EFO_0005110
Diseaseglucagon measurement, glucose tolerance test

MACF1 HERC1

3.65e-0461472EFO_0004307, EFO_0008463
DiseaseLissencephaly

TMTC3 MACF1

3.65e-0461472C0266463
Diseasefree cholesterol to total lipids in large LDL percentage

CELSR2 MACF1 PCCB PLTP

5.19e-04741474EFO_0022280
Diseasecommon bile duct neoplasm (is_marker_for)

MTAP MSLN

6.77e-0481472DOID:4608 (is_marker_for)
Diseaseobesity (implicated_via_orthology)

ADAMTS9 NCOA1 C3 ZFHX3 GNAQ PLXNB3

7.52e-042151476DOID:9970 (implicated_via_orthology)
Diseaseresponse to hydrochlorothiazide, diastolic blood pressure change measurement

TTC6 MTAP

1.08e-03101472EFO_0005202, EFO_0006945
Diseasecholesteryl esters to total lipids in small HDL percentage

CELSR2 PCCB PLTP

1.29e-03431473EFO_0022254
Diseaseatopic eczema, childhood onset asthma, atopic march

KIF3A EFHC1

1.32e-03111472EFO_0000274, EFO_0007755, MONDO_0005405
Diseasetotal lipids in very small VLDL measurement

SNX17 CELSR2 PCCB

1.47e-03451473EFO_0022156
Diseaselow density lipoprotein cholesterol measurement, alcohol consumption measurement

N4BP2L1 SNX17 CELSR2 PCCB

1.54e-03991474EFO_0004611, EFO_0007878
DiseaseEndogenous depression

GSK3A DIXDC1 GNAS

1.57e-03461473C0011573
Diseaselow density lipoprotein cholesterol measurement, alcohol drinking

N4BP2L1 SNX17 CELSR2 PCCB

1.72e-031021474EFO_0004329, EFO_0004611
DiseaseAmino Acid Metabolism, Inherited Disorders

SECISBP2 PRODH

1.85e-03131472C0750905
DiseaseAlzheimer disease, cognitive decline measurement, Cognitive impairment

PDS5B TIAM2

1.85e-03131472EFO_0007710, HP_0100543, MONDO_0004975
DiseaseAmino Acid Metabolism, Inborn Errors

SECISBP2 PRODH

1.85e-03131472C0002514
Diseasepre-eclampsia (implicated_via_orthology)

PTGS1 C3

1.85e-03131472DOID:10591 (implicated_via_orthology)
Diseasecholesterol in medium LDL measurement

SNX17 CELSR2 PLTP

1.89e-03491473EFO_0022224
Diseasecholesterol in small LDL measurement

SNX17 CELSR2 PLTP

1.89e-03491473EFO_0022227
Diseasedevelopmental disorder of mental health (implicated_via_orthology)

GRIN2D PLXNB3 RASAL2

1.89e-03491473DOID:0060037 (implicated_via_orthology)
Diseasevery low density lipoprotein cholesterol measurement

N4BP2L1 SNX17 CELSR2 PCCB PLTP BRWD1

1.98e-032601476EFO_0008317
Diseasecognitive function measurement, self reported educational attainment

PPA2 PITX3 BSN MED27 PCCB NUP160 CDH9

2.08e-033551477EFO_0004784, EFO_0008354
Diseasephospholipids in very small VLDL measurement

SNX17 CELSR2 PCCB

2.12e-03511473EFO_0022300
Diseasesickle cell anemia (is_marker_for)

PECAM1 C3

2.16e-03141472DOID:10923 (is_marker_for)
Diseasephospholipids in IDL measurement

N4BP2L1 CELSR2 PLTP

2.24e-03521473EFO_0022164
Diseasetotal lipids in medium LDL

SNX17 CELSR2 PLTP

2.24e-03521473EFO_0022180
Diseasediet measurement

SECISBP2L ACSM1 PTPRT CELSR2 PPA2 UBR3 ZFHX3 GNAQ MED27 DNAH5 PCCA PCCB CDH4

2.33e-03104914713EFO_0008111
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

CELSR2 PCCB PLTP BRWD1

2.34e-031111474EFO_0004530, EFO_0008595
Diseasecholesterol in small VLDL measurement

SNX17 CELSR2 PLTP

2.36e-03531473EFO_0022228
DiseaseRASopathy

LZTR1 SPRED1

2.48e-03151472cv:C5555857
DiseaseHypertriglyceridemia

CELSR2 PLTP

2.48e-03151472C0020557
Diseaselifestyle measurement, alcohol consumption measurement

RANBP6 CSMD2 NUP205 PLOD2

2.66e-031151474EFO_0007878, EFO_0010724
Diseasefree cholesterol to total lipids in large HDL percentage

N4BP2L1 CELSR2 PLTP

2.77e-03561473EFO_0022279
DiseaseAlzheimer's disease (implicated_via_orthology)

APLP1 PTGS1 RCOR3

2.91e-03571473DOID:10652 (implicated_via_orthology)
Diseaselung carcinoma

SECISBP2L PDS5B DOK5 COL6A3 COL6A6 TRIM26 MTAP NCOA1

2.96e-034821478EFO_0001071
Diseaselow density lipoprotein cholesterol measurement, phospholipid measurement

N4BP2L1 CELSR2 PLTP BRWD1

3.11e-031201474EFO_0004611, EFO_0004639
Diseaseresponse to radiation, Urinary retention

COL6A3 PTPRS

3.19e-03171472GO_0009314, HP_0000016
Diseasemuscular dystrophy (is_implicated_in)

COL6A3 DYSF

3.19e-03171472DOID:9884 (is_implicated_in)
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

CELSR2 PLTP

3.19e-03171472EFO_0022232
Diseasesleep duration, high density lipoprotein cholesterol measurement

CELSR2 MACF1 SPRED1 PLTP

3.20e-031211474EFO_0004612, EFO_0005271
DiseaseAge-related macular degeneration

ABCA4 C3

3.58e-03181472cv:C0242383
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

HERC1 BSN

3.58e-03181472HP_0002373
DiseaseDisorder of organic acid metabolism

PCCA PCCB

3.58e-03181472cv:C1263739
Diseasepolycystic kidney disease (biomarker_via_orthology)

PTGS1 GNAS

3.99e-03191472DOID:0080322 (biomarker_via_orthology)
Diseasebrain connectivity measurement

SATB2 WARS1 DYSF HEXIM2 FBXO16 ENO4 PCCA

4.02e-034001477EFO_0005210
Diseasecystatin C measurement

DNAJC16 KIF3A ULK3 CD93 ZNF778 GNAS BSN

4.13e-034021477EFO_0004617
Diseasetriglycerides in small LDL measurement

CELSR2 PCCB PLTP

4.22e-03651473EFO_0022323
Diseasecholesterol in large VLDL measurement

CELSR2 PCCB PLTP

4.22e-03651473EFO_0021902
Diseasecholesterol in very large VLDL measurement

CELSR2 PCCB PLTP

4.22e-03651473EFO_0022230
Diseasecreatinine measurement

DNAJC16 SNX17 SLC47A2 ULK3 CELSR2 RCOR3 ZFHX3 GNAS BSN QSOX2 PRODH VTI1B

4.23e-0399514712EFO_0004518
Diseasecalcium measurement

SECISBP2L BTBD10 CELSR2 PPA2 MACF1 ZFHX3 GNAQ GNAS PCCB

4.35e-036281479EFO_0004838
Diseaseasthma

PDS5B COL6A3 TRIM26 RANBP6 DYSF TIAM2 KIF3A ADAMTS9 ZC3H12D MROH7

4.50e-0375114710MONDO_0004979
Diseasetotal lipids in small VLDL

CELSR2 PCCB PLTP

4.60e-03671473EFO_0022148
Diseasetotal lipids in large VLDL

CELSR2 PCCB PLTP

4.60e-03671473EFO_0022175
Diseasephospholipids:total lipids ratio, intermediate density lipoprotein measurement

MACF1 PCCB PLTP

4.60e-03671473EFO_0008595, EFO_0020946
Diseasetestosterone measurement

STARD13 SATB2 WARS1 METRNL MCHR2 ANKS1B PPA2 NCOA1 MACF1 ZFHX3 MMP12 PCCB NUP160 BRWD1

4.70e-03127514714EFO_0004908
Diseasefree cholesterol in large VLDL measurement

CELSR2 PCCB PLTP

4.79e-03681473EFO_0022265
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

CELSR2 PLTP

4.86e-03211472EFO_0022246

Protein segments in the cluster

PeptideGeneStartEntry
YEFFLPDNMEALQIR

PFKFB1

91

P16118
LRMEETPTEYLQRGF

ABCF1

701

Q8NE71
ARRQFEFYLEEMILP

BTBD10

281

Q9BSF8
FNELRKQDPYRIENM

CDC23

286

Q9UJX2
TNVRATFENPMYDRN

CSMD2

3451

Q7Z408
YRDFQELLMNAPESQ

ABCA4

106

P78363
MPQEERLSRYQQFKD

DDX39B

321

Q13838
DIERVNIVFNYDMPE

DDX39A

351

O00148
YERPEQSVNKIAMRE

CDKL3

36

Q8IVW4
RQRNSSMDEEIENPY

DIXDC1

181

Q155Q3
VPERAESRAMENQYS

CD93

631

Q9NPY3
RQMYPELQIARVEQA

APLP1

96

P51693
MQDFFIDLRLPYSVV

C3

826

P01024
NYVFAPLQDMIERAI

ABCA13

3521

Q86UQ4
VLEYEMTQFDRRGPI

ANKRD50

1296

Q9ULJ7
RITYFMEDSIPQFRI

CELSR2

746

Q9HCU4
QMEQVRRIPEEYSLG

MROH7

991

Q68CQ1
MRVGAEYQARIPEFD

RCOR3

1

Q9P2K3
ERIFAQYMVPHNLET

PDS5B

456

Q9NTI5
DQFIDRTTMRPQSFY

MTAP

111

Q13126
EDDPQAVLQTMRRYV

QSOX2

456

Q6ZRP7
YRINNYTPDMNREDV

MMP12

116

P39900
YTPDMNREDVDYAIR

MMP12

121

P39900
EYPFDLQSVIFRMVD

GNAQ

191

P50148
VRSNQMDEAEQYTRP

KCTD19

556

Q17RG1
RLAQCQVYDMRPETD

NUP205

1581

Q92621
DDIERYPQVRSMISQ

LRRC69

271

Q6ZNQ3
NYFDDIPRSKLERQM

ANKS1B

1006

Q7Z6G8
QHLQDVPYVMVRERE

DSG2

1006

Q14126
ARAVMNFVVRYRPDE

PLOD3

646

O60568
RFREIIDQFEENMPV

C20orf96

301

Q9NUD7
AEARPFEVLMQFLYT

LZTR1

516

Q8N653
PYREMEHLRQFRQDV

LETMD1

121

Q6P1Q0
EFISKMSYQDPRREQ

LATS1

136

O95835
MSQERPTFYRQELNK

MAPK14

1

Q16539
YPMTDAERVDQAYRE

GALNT10

96

Q86SR1
QRFQIMKVDRPYDSL

HERC1

4791

Q15751
NVPRNYVMIDDISEL

BSN

3226

Q9UPA5
MYPVFNELERVNLSA

PDCD10

26

Q9BUL8
RAVEPQLQEEERMVY

PLTP

251

P55058
TNHMDEVQIPFLDYR

PLXNA3

1286

P51805
QMVERYYADIRQSSP

PLXNB3

1821

Q9ULL4
EMLSQPRISYDAQFE

PECAM1

406

P16284
EEMTRRYNINIYAPT

DNAJC16

311

Q9Y2G8
LFNLMQEYPDDRTSR

RASAL2

491

Q9UJF2
ISMDVFVRILQPERY

KDM4B

316

O94953
MYFTNLQERSPKIER

LRP6

1071

O75581
TIIMPNEFQQDYDIR

LY75

736

O60449
VEREQSERFNVYLMP

DOK5

131

Q9P104
MDRVNAIPFTYEQLD

MSLN

336

Q13421
PRFKDFQRMYRDAQE

METRNL

286

Q641Q3
YVDDVISRIDRMFPE

MED27

161

Q6P2C8
YFLEMNTRLQVEHPV

PCCA

346

P05165
FQILMDDPFQIYRAE

PCDHB10

106

Q9UN67
IRESREMRLQPFNEY

PTGS1

451

P23219
IIDNFIPRDYQEMIE

KIF3A

591

Q9Y496
RMEVENPNYALTSRF

ITPRID2

226

P28290
REPLAAVYQEMLAQA

IQGAP3

241

Q86VI3
YRPDLVDMERVQIQS

MACF1

236

Q9UPN3
MNERNYFVRDKLDPD

PLOD2

476

O00469
RTQRPAMVQTEDEYQ

PTPRS

1916

Q13332
VEMSYPRDQFQPAIR

PTPRT

856

O14522
VVYMVPDSNQREEQE

OR2A2

256

Q6IF42
ERYEPSETAKAQRQM

PLCD1

256

P51178
EREFFEIMPNYAKNI

PCCB

326

P05166
VMSVDRYFALVQPFR

MCHR2

126

Q969V1
YPRFVEVLVVADNRM

ADAMTS9

291

Q9P2N4
AFDMYQDPEVAQIIR

CEP104

201

O60308
QEDQEYEEVMILRRP

HECTD1

1696

Q9ULT8
SFENMRVFLQLRPEY

FASTKD5

111

Q7L8L6
ARYPQITFENMIVDN

IDH3G

241

P51553
REQIREMNPNYTEFK

GSK3A

341

P49840
HSFNVPMQLRIYEIE

KDM2B

331

Q8NHM5
TQEYQRESMLIDAPR

KDM2B

381

Q8NHM5
IEYVPFMNVDLRERF

CAPN7

221

Q9Y6W3
ILMDLVRPQDTYQFF

CENPC

836

Q03188
EVDERQTMPRPYTFQ

CRACD

526

Q6ZU35
ELMVPFTRDYNTLQE

INTS14

61

Q96SY0
PYVRDFVMNLVNSLD

COL6A3

656

P12111
QRTFPEIQRRDSYYM

IGHD

51

P01880
AVDPDRFMQQAVRYS

CDH4

531

P55283
NPENQFRVDYILSVM

GNAS

121

P63092
FRVDYILSVMNVPDF

GNAS

126

P63092
DRDPEAQFEMPYVVR

PRMT5

491

O14744
MPDVIDFLVLRQFYD

BRWD1

1046

Q9NSI6
PQEFLNRRYMTEVDY

CAPRIN2

366

Q6IMN6
QQAMEYYRENDVPRR

ENO4

21

A6NNW6
DVPMSTEEQYRIRQV

EFHC1

106

Q5JVL4
RFNYLDNRDPMETVQ

FBXO16

231

Q8IX29
LPDMSRENREQYQVV

CDH9

221

Q9ULB4
VKAPVYRTDRVMFQD

DYSF

1711

O75923
VDRQPRVALQYQMDS

IZUMO2

166

Q6UXV1
MESYELNPFINRRNA

MGP

26

P08493
ELEATFQRNRYPDMS

PITX3

76

O75364
FQRNRYPDMSTREEI

PITX3

81

O75364
RPEMVFYVENFDILQ

COL6A6

771

A6NMZ7
RVYPELQRFMAVSDV

FOCAD

556

Q5VW36
FELMPVIRIYAENNT

DNAH5

4561

Q8TE73
FQILMDDPFQIYRAE

PCDHB9

106

Q9Y5E1
TNRQDYIQMIPELFD

RTL1

641

A6NKG5
IDQDPYFRMTRDVAP

WARS1

311

P23381
YEPRVINQMLEFAFR

TAF9B

31

Q9HBM6
YEPRVINQMLEFAFR

TAF9

31

Q16594
PEGQEMYLRFDQTTR

STARD13

21

Q9Y3M8
DLPYEEEIMRNQFSV

XAB2

21

Q9HCS7
PYEAQRIMTEFQRQE

SHB

271

Q15464
RQDPDVSRLTQDYVM

SLC47A2

141

Q86VL8
RVTFRYDVLNAPLEM

TMEM132E

516

Q6IEE7
EYVPDNVVSMRRIVN

NKPD1

391

Q17RQ9
YRMERPKIQQQFSDL

PRPF6

131

O94906
RFDTVYDQMVQPQKR

IQCA1L

56

A6NCM1
EPSYARQLFQEVMTR

NCOA1

306

Q15788
YNTTQFLMNDRDPEE

HEXIM2

141

Q96MH2
DPNRRMSVAEQVDYV

SMG1

3626

Q96Q15
LSYQEMNAPSFRVER

GUCY1B2

31

O75343
RLMVDAEQTYFQPAI

PRODH

376

O43272
RIYQDERERSMNPNV

SATB2

431

Q9UPW6
ELVRFQDRMYQKDPV

SECISBP2

651

Q96T21
LYNVIAMAREQEIPF

SECISBP2L

756

Q93073
RMRVLELYANDPEFA

IMPG2

1216

Q9BZV3
DEYENLFNMIVEIPR

PPA2

86

Q9H2U2
VMYEVQSNFRILELP

MROH2B

91

Q7Z745
VVENIYKNREPVRQM

STXBP3

61

O00186
VIRDDQDPREMYLQS

NUP160

446

Q12769
CMVRRQAEEIYENIP

RANBP6

31

O60518
YRMILQQDFTSIRFP

ACSM1

321

Q08AH1
YRFPNMVVAQVTRES

GTF2H4

336

Q92759
EDLDEIVARYVQPMA

SUPT6H

1406

Q7KZ85
REQLEKYMQAVRQDP

SNX17

76

Q15036
QFSQEDMPRVRKRIY

SENP5

731

Q96HI0
PAQRTLYREVMVENY

ZNF880

26

Q6PDB4
PSQRDLYRDVMLENY

ZNF778

61

Q96MU6
LPRQLQMVTEDEYEV

ZFR2

696

Q9UPR6
FDPENEYVLMNRAIT

TTC6

411

Q86TZ1
SDPLRQNIYENFMRE

TIAM2

451

Q8IVF5
EEARYYQLQPMVREL

KCTD15

136

Q96SI1
RMEQPRNCDDEVYEL

TIE1

1071

P35590
SPFEDLNARRVYMQS

SPRED1

176

Q7Z699
RLLEYSAFMEVQRDP

TEAD3

226

Q99594
RAYFMQLQTRSADEP

POLR3K

76

Q9Y2Y1
AELMQDTRDFLNRYP

TRIM26

251

Q12899
YSVFPRDQVDRVMAA

ZC3H12D

486

A2A288
LMRFIFRTDPQYTIE

ZNF404

81

Q494X3
TMRFLEDAAAPYREQ

TRIM10

131

Q9UDY6
QEFDPVMVILRTVYR

UBR3

861

Q6ZT12
EFLDPAQRDLYRDVM

ZFP14

21

Q9HCL3
RMYDVLQETIENDFP

TMC2

731

Q8TDI7
EEADQLYRQAISMRP

TMTC3

546

Q6ZXV5
QRVLRMEEFFPETYR

TTLL10

276

Q6ZVT0
EMEEELRYAPLSFRN

VTI1B

61

Q9UEU0
APEMVCQRQYDARVD

ULK3

181

Q6PHR2
YFDPATVRQLMAQQE

ZFHX3

3066

Q15911
VMALENNYEVIFREP

N4BP2L1

131

Q5TBK1
NDQPVTFLDRYRMEV

MYOM3

1371

Q5VTT5
SYMVRYNQPRVEEAL

GRIN2D

731

O15399