Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	signaling receptor complex adaptor activity	GNB4 GNB1 GNB2 GNB3	1.00e-05	54	50	4	GO:0030159
GeneOntologyMolecularFunction	signaling adaptor activity	GNB4 GNB1 GNB2 GNB3	3.04e-04	129	50	4	GO:0035591
GeneOntologyMolecularFunction	olfactory receptor activity	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 OR2A2	6.95e-04	431	50	6	GO:0004984
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	KCNC1 KCNC2	8.16e-04	17	50	2	GO:0099508
GeneOntologyMolecularFunction	protein-cysteine S-palmitoyltransferase activity	ZDHHC12 ZDHHC8	1.92e-03	26	50	2	GO:0019706
GeneOntologyMolecularFunction	protein-cysteine S-acyltransferase activity	ZDHHC12 ZDHHC8	1.92e-03	26	50	2	GO:0019707
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	MST1 PHKA2 CSF1R MAP4K3 POLE DGKE UAP1L1 MUSK	2.14e-03	938	50	8	GO:0016772
GeneOntologyMolecularFunction	delayed rectifier potassium channel activity	KCNC1 KCNC2	2.23e-03	28	50	2	GO:0005251
GeneOntologyMolecularFunction	S-acyltransferase activity	ZDHHC12 ZDHHC8	2.56e-03	30	50	2	GO:0016417
GeneOntologyBiologicalProcess	globus pallidus development	KCNC1 KCNC2	3.31e-05	4	49	2	GO:0021759
GeneOntologyBiologicalProcess	G protein-coupled receptor signaling pathway	OR2A14 OR2A7 OR2A12 OR2A4 DGKE OR2A25 GNB4 GNB1 GNB2 GNB3 PTGIR OR2A2	7.72e-05	1395	49	12	GO:0007186
GeneOntologyCellularComponent	heterotrimeric G-protein complex	GNB4 GNB1 GNB2 GNB3	1.22e-06	35	48	4	GO:0005834
GeneOntologyCellularComponent	GTPase complex	GNB4 GNB1 GNB2 GNB3	2.33e-06	41	48	4	GO:1905360
GeneOntologyCellularComponent	extrinsic component of cytoplasmic side of plasma membrane	GNB4 GNB1 GNB2 GNB3	8.23e-06	56	48	4	GO:0031234
GeneOntologyCellularComponent	extrinsic component of plasma membrane	GNB4 GNB1 GNB2 GNB3	2.75e-04	137	48	4	GO:0019897
GeneOntologyCellularComponent	mitotic spindle midzone	OR2A7 OR2A4	6.07e-04	16	48	2	GO:1990023
GeneOntologyCellularComponent	cytoplasmic side of plasma membrane	GNB4 GNB1 GNB2 GNB3	8.53e-04	185	48	4	GO:0009898
GeneOntologyCellularComponent	axolemma	KCNC1 KCNC2	1.05e-03	21	48	2	GO:0030673
GeneOntologyCellularComponent	cytoplasmic side of membrane	GNB4 GNB1 GNB2 GNB3	1.90e-03	230	48	4	GO:0098562
GeneOntologyCellularComponent	extrinsic component of membrane	GNB4 GNB1 GNB2 GNB3	1.90e-03	230	48	4	GO:0019898
GeneOntologyCellularComponent	cell projection membrane	DPEP1 KCNC1 KCNC2 PIEZO1 GNB1	3.01e-03	431	48	5	GO:0031253
GeneOntologyCellularComponent	Flemming body	OR2A7 OR2A4	3.09e-03	36	48	2	GO:0090543
GeneOntologyCellularComponent	side of membrane	DPEP1 LPA GNB4 GNB1 GNB2 GNB3 MUSK	3.62e-03	875	48	7	GO:0098552
GeneOntologyCellularComponent	spindle midzone	OR2A7 OR2A4	3.81e-03	40	48	2	GO:0051233
GeneOntologyCellularComponent	neuronal cell body membrane	KCNC1 KCNC2	4.39e-03	43	48	2	GO:0032809
GeneOntologyCellularComponent	mitotic spindle pole	OR2A7 OR2A4	4.39e-03	43	48	2	GO:0097431
GeneOntologyCellularComponent	cell body	CSF1R KCNC1 KCNC2 GNB4 GNB1 GNB2 GNB3	5.02e-03	929	48	7	GO:0044297
GeneOntologyCellularComponent	cell body membrane	KCNC1 KCNC2	5.23e-03	47	48	2	GO:0044298
Domain	Guanine_nucleotide-bd_bsu	GNB4 GNB1 GNB2 GNB3	2.46e-10	5	51	4	IPR016346
Domain	Gprotein_B	GNB4 GNB1 GNB2 GNB3	1.02e-08	10	51	4	IPR001632
Domain	K_chnl_volt-dep_Kv3	KCNC1 KCNC2	4.37e-05	4	51	2	IPR003974
Domain	G-protein_beta_WD-40_rep	GNB4 GNB1 GNB2 GNB3	8.48e-05	85	51	4	IPR020472
Domain	Olfact_rcpt	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 OR2A2	6.76e-04	393	51	6	IPR000725
Domain	Kringle	MST1 LPA	9.68e-04	17	51	2	IPR000001
Domain	Kringle_CS	MST1 LPA	9.68e-04	17	51	2	IPR018056
Domain	KRINGLE_2	MST1 LPA	9.68e-04	17	51	2	PS50070
Domain	Kringle	MST1 LPA	9.68e-04	17	51	2	PF00051
Domain	KRINGLE_1	MST1 LPA	9.68e-04	17	51	2	PS00021
Domain	KR	MST1 LPA	9.68e-04	17	51	2	SM00130
Domain	WD40_repeat_CS	GNB4 GNB1 GNB2 GNB3	1.04e-03	164	51	4	IPR019775
Domain	zf-DHHC	ZDHHC12 ZDHHC8	1.78e-03	23	51	2	PF01529
Domain	Metal_Hydrolase	DPEP1 ADA2	1.94e-03	24	51	2	IPR032466
Domain	DHHC	ZDHHC12 ZDHHC8	2.11e-03	25	51	2	PS50216
Domain	Znf_DHHC_palmitoyltrfase	ZDHHC12 ZDHHC8	2.11e-03	25	51	2	IPR001594
Domain	GPCR_Rhodpsn_7TM	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 PTGIR OR2A2	2.17e-03	670	51	7	IPR017452
Domain	7tm_1	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 PTGIR OR2A2	2.31e-03	677	51	7	PF00001
Domain	K_chnl_volt-dep_Kv	KCNC1 KCNC2	2.46e-03	27	51	2	IPR003968
Domain	G_PROTEIN_RECEP_F1_1	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 PTGIR OR2A2	2.46e-03	685	51	7	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 PTGIR OR2A2	2.59e-03	691	51	7	PS50262
Domain	GPCR_Rhodpsn	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 PTGIR OR2A2	2.61e-03	692	51	7	IPR000276
Domain	Kringle-like	MST1 LPA	3.44e-03	32	51	2	IPR013806
Domain	VG_K_chnl	KCNC1 KCNC2	3.66e-03	33	51	2	IPR028325
Domain	WD40	GNB4 GNB1 GNB2 GNB3	5.42e-03	259	51	4	PF00400
Domain	WD40	GNB4 GNB1 GNB2 GNB3	6.11e-03	268	51	4	SM00320
Domain	WD40_repeat	GNB4 GNB1 GNB2 GNB3	6.43e-03	272	51	4	IPR001680
Domain	WD_REPEATS_1	GNB4 GNB1 GNB2 GNB3	6.93e-03	278	51	4	PS00678
Domain	WD_REPEATS_2	GNB4 GNB1 GNB2 GNB3	7.02e-03	279	51	4	PS50082
Domain	WD_REPEATS_REGION	GNB4 GNB1 GNB2 GNB3	7.02e-03	279	51	4	PS50294
Domain	WD40_repeat_dom	GNB4 GNB1 GNB2 GNB3	8.71e-03	297	51	4	IPR017986
Domain	-	CSMD1 ZZEF1	8.88e-03	52	51	2	2.60.120.290
Domain	Sushi	SRPX2 CSMD1	8.88e-03	52	51	2	PF00084
Domain	BTB_2	KCNC1 KCNC2	9.22e-03	53	51	2	PF02214
Domain	T1-type_BTB	KCNC1 KCNC2	9.22e-03	53	51	2	IPR003131
Domain	CCP	SRPX2 CSMD1	9.56e-03	54	51	2	SM00032
Domain	SUSHI	SRPX2 CSMD1	1.02e-02	56	51	2	PS50923
Domain	Sushi_SCR_CCP_dom	SRPX2 CSMD1	1.06e-02	57	51	2	IPR000436
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2 GNB3 PTGIR	1.23e-09	19	38	5	MM15021
Pathway	REACTOME_PROSTACYCLIN_SIGNALLING_THROUGH_PROSTACYCLIN_RECEPTOR	GNB4 GNB1 GNB2 GNB3 PTGIR	1.23e-09	19	38	5	M926
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	KCNC2 GNB4 GNB1 GNB2 GNB3	2.07e-08	32	38	5	MM14983
Pathway	REACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION	KCNC2 GNB4 GNB1 GNB2 GNB3	8.57e-08	42	38	5	M791
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2 GNB3	2.11e-07	20	38	4	M27853
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_CDC42	GNB4 GNB1 GNB2 GNB3	2.11e-07	20	38	4	MM15572
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNC1 KCNC2 GNB4 GNB1 GNB2 GNB3	2.23e-07	98	38	6	MM14545
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2 GNB3	2.60e-07	21	38	4	M27409
Pathway	REACTOME_PRESYNAPTIC_FUNCTION_OF_KAINATE_RECEPTORS	GNB4 GNB1 GNB2 GNB3	2.60e-07	21	38	4	MM15159
Pathway	REACTOME_POTASSIUM_CHANNELS	KCNC1 KCNC2 GNB4 GNB1 GNB2 GNB3	3.00e-07	103	38	6	M1073
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2 GNB3	3.17e-07	22	38	4	MM15016
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_12	GNB4 GNB1 GNB2 GNB3	3.17e-07	22	38	4	M841
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2 GNB3	3.83e-07	23	38	4	MM15033
Pathway	KEGG_MEDICUS_REFERENCE_LPAR_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	3.83e-07	23	38	4	M47549
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2 GNB3	4.59e-07	24	38	4	M13115
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2 GNB3	4.59e-07	24	38	4	M18308
Pathway	REACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR	GNB4 GNB1 GNB2 GNB3	4.59e-07	24	38	4	MM15088
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	4.59e-07	24	38	4	M47460
Pathway	REACTOME_G_PROTEIN_ACTIVATION	GNB4 GNB1 GNB2 GNB3	4.59e-07	24	38	4	MM14794
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2 GNB3	5.45e-07	25	38	4	M14301
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2 GNB3	5.45e-07	25	38	4	MM15056
Pathway	REACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1	GNB4 GNB1 GNB2 GNB3	5.45e-07	25	38	4	M811
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	KCNC2 GNB4 GNB1 GNB2 GNB3	5.77e-07	61	38	5	MM15071
Pathway	REACTOME_G_BETA_GAMMA_SIGNALLING_THROUGH_PI3KGAMMA	GNB4 GNB1 GNB2 GNB3	6.43e-07	26	38	4	MM15017
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	6.43e-07	26	38	4	M47561
Pathway	KEGG_MEDICUS_PATHOGEN_HIV_GP120_TO_CXCR4_GNB_G_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	6.43e-07	26	38	4	M47562
Pathway	KEGG_MEDICUS_REFERENCE_CCR5_GNB_G_PLCB_G_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	6.43e-07	26	38	4	M47557
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_PI3K_AKT_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	6.43e-07	26	38	4	M47456
Pathway	KEGG_MEDICUS_REFERENCE_CXCR_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	7.53e-07	27	38	4	M47454
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2 GNB3	7.53e-07	27	38	4	MM15664
Pathway	REACTOME_ADRENALINE_NORADRENALINE_INHIBITS_INSULIN_SECRETION	GNB4 GNB1 GNB2 GNB3	8.77e-07	28	38	4	M10679
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_PI3K_JNK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.02e-06	29	38	4	M47466
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1 GNB2 GNB3	1.17e-06	30	38	4	M18193
Pathway	REACTOME_ACTIVATION_OF_G_PROTEIN_GATED_POTASSIUM_CHANNELS	GNB4 GNB1 GNB2 GNB3	1.17e-06	30	38	4	MM14542
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	KCNC2 GNB4 GNB1 GNB2 GNB3	1.33e-06	72	38	5	MM14631
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2 GNB3	1.34e-06	31	38	4	MM15094
Pathway	KEGG_MEDICUS_REFERENCE_CXCR4_GNB_G_PLCB_PKC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.34e-06	31	38	4	M47554
Pathway	KEGG_MEDICUS_REFERENCE_CCR_CXCR_GNB_G_PI3K_RAC_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.34e-06	31	38	4	M47455
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_VGPCR_TO_GNB_G_ERK_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.34e-06	31	38	4	M47459
Pathway	KEGG_MEDICUS_REFERENCE_CCR2_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.34e-06	31	38	4	M47540
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_US28_TO_GNB_G_PI3K_NFKB_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.34e-06	31	38	4	M47541
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2 GNB3	1.53e-06	32	38	4	M14309
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1 GNB2 GNB3	1.53e-06	32	38	4	MM15148
Pathway	REACTOME_ACTIVATION_OF_KAINATE_RECEPTORS_UPON_GLUTAMATE_BINDING	GNB4 GNB1 GNB2 GNB3	1.53e-06	32	38	4	MM15143
Pathway	KEGG_MEDICUS_REFERENCE_GPCR_PI3K_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.53e-06	32	38	4	M47962
Pathway	REACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS	GNB4 GNB1 GNB2 GNB3	1.53e-06	32	38	4	M861
Pathway	REACTOME_G_PROTEIN_BETA_GAMMA_SIGNALLING	GNB4 GNB1 GNB2 GNB3	1.74e-06	33	38	4	MM15027
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2 GNB3	1.74e-06	33	38	4	MM15020
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 GNB3	1.74e-06	33	38	4	MM15058
Pathway	KEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNB_G_RHO_SIGNALING_PATHWAY	GNB4 GNB1 GNB2 GNB3	1.74e-06	33	38	4	M47550
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1 GNB2 GNB3	1.74e-06	33	38	4	MM15066
Pathway	REACTOME_GLUCAGON_TYPE_LIGAND_RECEPTORS	GNB4 GNB1 GNB2 GNB3	1.74e-06	33	38	4	M10322
Pathway	REACTOME_SIGNAL_AMPLIFICATION	GNB4 GNB1 GNB2 GNB3	1.74e-06	33	38	4	M9379
Pathway	REACTOME_GLUCAGON_SIGNALING_IN_METABOLIC_REGULATION	GNB4 GNB1 GNB2 GNB3	1.74e-06	33	38	4	M11575
Pathway	REACTOME_PLATELET_HOMEOSTASIS	GNB4 GNB1 GNB2 GNB3 PTGIR	1.74e-06	76	38	5	MM15051
Pathway	REACTOME_REGULATION_OF_INSULIN_SECRETION	KCNC2 GNB4 GNB1 GNB2 GNB3	1.98e-06	78	38	5	M1921
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2 GNB3	2.21e-06	35	38	4	M1075
Pathway	REACTOME_INWARDLY_RECTIFYING_K_CHANNELS	GNB4 GNB1 GNB2 GNB3	2.49e-06	36	38	4	MM14544
Pathway	REACTOME_COOPERATION_OF_PDCL_PHLP1_AND_TRIC_CCT_IN_G_PROTEIN_BETA_FOLDING	GNB4 GNB1 GNB2 GNB3	3.10e-06	38	38	4	M27656
Pathway	REACTOME_PLATELET_HOMEOSTASIS	GNB4 GNB1 GNB2 GNB3 PTGIR	3.22e-06	86	38	5	M916
Pathway	REACTOME_CHAPERONIN_MEDIATED_PROTEIN_FOLDING	GNB4 GNB1 GNB2 GNB3	3.45e-06	39	38	4	MM15003
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2 GNB3	3.83e-06	40	38	4	MM15115
Pathway	REACTOME_ADORA2B_MEDIATED_ANTI_INFLAMMATORY_CYTOKINES_PRODUCTION	GNB4 GNB1 GNB2 GNB3	5.14e-06	43	38	4	M29837
Pathway	REACTOME_VASOPRESSIN_REGULATES_RENAL_WATER_HOMEOSTASIS_VIA_AQUAPORINS	GNB4 GNB1 GNB2 GNB3	5.14e-06	43	38	4	M933
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2 GNB3	5.14e-06	43	38	4	M954
Pathway	REACTOME_GABA_B_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2 GNB3	5.64e-06	44	38	4	MM15709
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1 GNB2 GNB3	6.18e-06	45	38	4	MM15040
Pathway	REACTOME_GPER1_SIGNALING	GNB4 GNB1 GNB2 GNB3	6.18e-06	45	38	4	M45008
Pathway	REACTOME_G_ALPHA_Z_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 GNB3	8.02e-06	48	38	4	M10775
Pathway	REACTOME_INTEGRATION_OF_ENERGY_METABOLISM	KCNC2 GNB4 GNB1 GNB2 GNB3	9.87e-06	108	38	5	M17034
Pathway	REACTOME_AQUAPORIN_MEDIATED_TRANSPORT	GNB4 GNB1 GNB2 GNB3	1.11e-05	52	38	4	M920
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	GNB4 GNB1 GNB2 GNB3	1.96e-05	60	38	4	MM14964
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2 GNB3	1.96e-05	60	38	4	M976
Pathway	REACTOME_GABA_RECEPTOR_ACTIVATION	GNB4 GNB1 GNB2 GNB3	1.96e-05	60	38	4	MM15708
Pathway	REACTOME_CA2_PATHWAY	GNB4 GNB1 GNB2 GNB3	2.24e-05	62	38	4	M27321
Pathway	REACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION	DPEP1 GNB4 GNB1 GNB2 GNB3	2.81e-05	134	38	5	M29840
Pathway	REACTOME_OPIOID_SIGNALLING	GNB4 GNB1 GNB2 GNB3	3.83e-05	71	38	4	MM14491
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	GNB4 GNB1 GNB2 GNB3	3.83e-05	71	38	4	MM15590
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 GNB3 PTGIR	3.84e-05	143	38	5	MM15055
Pathway	REACTOME_EXTRA_NUCLEAR_ESTROGEN_SIGNALING	GNB4 GNB1 GNB2 GNB3	4.76e-05	75	38	4	M27874
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 GNB3	5.27e-05	77	38	4	MM15044
Pathway	REACTOME_PLATELET_ACTIVATION_SIGNALING_AND_AGGREGATION	LPA DGKE GNB4 GNB1 GNB2 GNB3	5.86e-05	257	38	6	MM15454
Pathway	REACTOME_G_ALPHA_S_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 GNB3 PTGIR	6.00e-05	157	38	5	M4904
Pathway	REACTOME_G_ALPHA_12_13_SIGNALLING_EVENTS	GNB4 GNB1 GNB2 GNB3	6.13e-05	80	38	4	M800
Pathway	REACTOME_OPIOID_SIGNALLING	GNB4 GNB1 GNB2 GNB3	9.71e-05	90	38	4	M6467
Pathway	REACTOME_OLFACTORY_SIGNALING_PATHWAY	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 GNB1 OR2A2	1.08e-04	417	38	7	M4072
Pathway	REACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS	GNB4 GNB1 GNB2 GNB3	1.15e-04	94	38	4	M797
Pathway	WP_RAS_SIGNALING	CSF1R GNB4 GNB1 GNB2 GNB3	1.27e-04	184	38	5	M39764
Pathway	REACTOME_PROTEIN_FOLDING	GNB4 GNB1 GNB2 GNB3	1.35e-04	98	38	4	M776
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	DGKE GNB4 GNB1 GNB2 GNB3	2.35e-04	210	38	5	MM15043
Pathway	REACTOME_SENSORY_PERCEPTION	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 GNB1 GNB3 OR2A2	2.41e-04	636	38	8	M41834
Pathway	REACTOME_NEURONAL_SYSTEM	KCNC1 KCNC2 GNB4 GNB1 GNB2 GNB3	2.50e-04	335	38	6	MM14503
Pathway	REACTOME_G_ALPHA_Q_SIGNALLING_EVENTS	DGKE GNB4 GNB1 GNB2 GNB3	2.74e-04	217	38	5	M18437
Pathway	REACTOME_LEISHMANIA_INFECTION	DPEP1 GNB4 GNB1 GNB2 GNB3	2.86e-04	219	38	5	M29836
Pathway	REACTOME_BETA_CATENIN_INDEPENDENT_WNT_SIGNALING	GNB4 GNB1 GNB2 GNB3	3.24e-04	123	38	4	MM14988
Pathway	REACTOME_SIGNALING_BY_WNT	GNB4 GNB1 GNB2 GNB3 ZRANB1	4.27e-04	239	38	5	MM14756
Pathway	REACTOME_ESR_MEDIATED_SIGNALING	GNB4 GNB1 GNB2 GNB3	4.36e-04	133	38	4	MM15529
Pathway	REACTOME_INCRETIN_SYNTHESIS_SECRETION_AND_INACTIVATION	GNB1 GNB3	4.59e-04	12	38	2	MM15036
Pathway	KEGG_OLFACTORY_TRANSDUCTION	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 OR2A2	5.55e-04	389	38	6	M14091
Pathway	REACTOME_NEUROTRANSMITTER_RECEPTORS_AND_POSTSYNAPTIC_SIGNAL_TRANSMISSION	GNB4 GNB1 GNB2 GNB3	5.89e-04	144	38	4	MM14501
Pubmed	Diversity among the beta subunits of heterotrimeric GTP-binding proteins: characterization of a novel beta-subunit cDNA.	GNB4 GNB1 GNB2 GNB3	4.10e-12	4	51	4	1543505
Pubmed	The role of G protein beta subunits in the release of ATP from human erythrocytes.	GNB4 GNB1 GNB2 GNB3	4.10e-12	4	51	4	12512701
Pubmed	Identification of Gnr1p, a negative regulator of G alpha signalling in Schizosaccharomyces pombe, and its complementation by human G beta subunits.	GNB4 GNB1 GNB2 GNB3	6.14e-11	6	51	4	16884933
Pubmed	The gene for the beta-subunit of retinal transducin (Gnb-1) maps to distal mouse chromosome 4, and related sequences map to mouse chromosomes 5 and 8.	GNB4 GNB1 GNB2 GNB3	2.86e-10	8	51	4	2328987
Pubmed	Fidelity of G protein beta-subunit association by the G protein gamma-subunit-like domains of RGS6, RGS7, and RGS11.	GNB4 GNB1 GNB2 GNB3	5.14e-10	9	51	4	10339615
Pubmed	Gβ2 Regulates the Multipolar-Bipolar Transition of Newborn Neurons in the Developing Neocortex.	GNB4 GNB1 GNB2 GNB3	8.55e-10	10	51	4	28334111
Pubmed	Expression of olfactory receptors, G-proteins and AxCAMs during the development and maturation of olfactory sensory neurons in the mouse.	GNB4 GNB1 GNB2 GNB3	8.55e-10	10	51	4	9733924
Pubmed	A Non-Canonical Function of Gβ as a Subunit of E3 Ligase in Targeting GRK2 Ubiquitylation.	GNB4 GNB1 GNB2 GNB3	1.34e-09	11	51	4	25982117
Pubmed	The G protein subunit gene families.	GNB4 GNB1 GNB2 GNB3	1.34e-09	11	51	4	10644457
Pubmed	Neural tube defects and impaired neural progenitor cell proliferation in Gbeta1-deficient mice.	GNB4 GNB1 GNB2 GNB3	2.01e-09	12	51	4	20186915
Pubmed	Differential sensitivity of P-Rex1 to isoforms of G protein betagamma dimers.	GNB4 GNB1 GNB2 GNB3	2.01e-09	12	51	4	16301321
Pubmed	Differential ability to form the G protein betagamma complex among members of the beta and gamma subunit families.	GNB4 GNB1 GNB2 GNB3	2.01e-09	12	51	4	8636150
Pubmed	Genomic organization of the murine G protein beta subunit genes and related processed pseudogenes.	GNB1 GNB2 GNB3	2.97e-09	3	51	3	11913780
Pubmed	Activation of heterotrimeric G proteins by a high energy phosphate transfer via nucleoside diphosphate kinase (NDPK) B and Gbeta subunits. Complex formation of NDPK B with Gbeta gamma dimers and phosphorylation of His-266 IN Gbeta.	GNB4 GNB1 GNB2 GNB3	5.53e-09	15	51	4	12486123
Pubmed	Role of molecular chaperones in G protein beta5/regulator of G protein signaling dimer assembly and G protein betagamma dimer specificity.	GNB4 GNB1 GNB2 GNB3	9.62e-09	17	51	4	19376773
Pubmed	The cationic region of Rhes mediates its interactions with specific Gbeta subunits.	GNB1 GNB2 GNB3	1.19e-08	4	51	3	19255495
Pubmed	Gialpha and Gbeta subunits both define selectivity of G protein activation by alpha2-adrenergic receptors.	GNB4 GNB1 GNB2	5.92e-08	6	51	3	16371464
Pubmed	G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.	GNB4 GNB1 GNB2 GNB3	8.18e-08	28	51	4	8858601
Pubmed	Ggamma13 colocalizes with gustducin in taste receptor cells and mediates IP3 responses to bitter denatonium.	GNB4 GNB1 GNB3	1.04e-07	7	51	3	10570481
Pubmed	Glucagon and regulation of glucose metabolism.	GNB4 GNB1 GNB2 GNB3	1.25e-07	31	51	4	12626323
Pubmed	A G protein gamma subunit-like domain shared between RGS11 and other RGS proteins specifies binding to Gbeta5 subunits.	GNB1 GNB2 GNB3	1.65e-07	8	51	3	9789084
Pubmed	Gβγ interacts with mTOR and promotes its activation.	GNB1 GNB2 GNB3	1.65e-07	8	51	3	24462769
Pubmed	The Dual Estrogen Receptor α Inhibitory Effects of the Tissue-Selective Estrogen Complex for Endometrial and Breast Safety.	GNB4 CHD6 GNB1 GNB2	4.85e-07	43	51	4	26487511
Pubmed	Specificities of Gβγ subunits for the SNARE complex before and after stimulation of α2a-adrenergic receptors.	GNB4 GNB1 GNB2	4.86e-07	11	51	3	34932372
Pubmed	Human Multisubunit E3 Ubiquitin Ligase Required for Heterotrimeric G-Protein β-Subunit Ubiquitination and Downstream Signaling.	GNB4 GNB1 GNB2	6.47e-07	12	51	3	34342229
Pubmed	Gbeta3 forms distinct dimers with specific Ggamma subunits and preferentially activates the beta3 isoform of phospholipase C.	GNB1 GNB2 GNB3	1.07e-06	14	51	3	19168127
Pubmed	Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder.	KCNC1 KCNC2	2.11e-06	2	51	2	31732108
Pubmed	Different roles of G protein subunits beta1 and beta2 in neutrophil function revealed by gene expression silencing in primary mouse neutrophils.	GNB1 GNB2	2.11e-06	2	51	2	20525682
Pubmed	Chromosomal localization of the genes encoding two forms of the G protein beta polypeptide, beta 1 and beta 3, in man.	GNB1 GNB3	2.11e-06	2	51	2	1979057
Pubmed	K(+) channel expression distinguishes subpopulations of parvalbumin- and somatostatin-containing neocortical interneurons.	KCNC1 KCNC2	2.11e-06	2	51	2	10531438
Pubmed	Kv3.1-containing K(+) channels are reduced in untreated schizophrenia and normalized with antipsychotic drugs.	KCNC1 KCNC2	2.11e-06	2	51	2	23628987
Pubmed	Developmental expression of potassium-channel subunit Kv3.2 within subpopulations of mouse hippocampal inhibitory interneurons.	KCNC1 KCNC2	2.11e-06	2	51	2	12000114
Pubmed	A unique role for Kv3 voltage-gated potassium channels in starburst amacrine cell signaling in mouse retina.	KCNC1 KCNC2	2.11e-06	2	51	2	15317859
Pubmed	Fast delayed rectifier potassium current: critical for input and output of the circadian system.	KCNC1 KCNC2	2.11e-06	2	51	2	21414897
Pubmed	KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression.	GNB4 GNB1 GNB2	5.88e-06	24	51	3	23209302
Pubmed	Control of voltage-gated K+ channel permeability to NMDG+ by a residue at the outer pore.	KCNC1 KCNC2	6.32e-06	3	51	2	19332619
Pubmed	Kv3 channels contribute to the delayed rectifier current in small cultured mouse dorsal root ganglion neurons.	KCNC1 KCNC2	6.32e-06	3	51	2	22673617
Pubmed	Two olfactory receptors-OR2A4/7 and OR51B5-differentially affect epidermal proliferation and differentiation.	OR2A7 OR2A4	6.32e-06	3	51	2	27315375
Pubmed	Mutations in G protein β subunits promote transformation and kinase inhibitor resistance.	GNB1 GNB2	6.32e-06	3	51	2	25485910
Pubmed	G protein beta gamma subunits. Simplified purification and properties of novel isoforms.	GNB1 GNB2	6.32e-06	3	51	2	8308009
Pubmed	Kv3.1b is a novel component of CNS nodes.	KCNC1 KCNC2	6.32e-06	3	51	2	12805291
Pubmed	Developmental changes in the expression of calbindin and potassium-channel subunits Kv3.1b and Kv3.2 in mouse Renshaw cells.	KCNC1 KCNC2	6.32e-06	3	51	2	16460880
Pubmed	Selective association of G protein beta(4) with gamma(5) and gamma(12) subunits in bovine tissues.	GNB4 GNB2	6.32e-06	3	51	2	10409705
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 OR2A2	1.04e-05	340	51	6	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 OR2A2	1.04e-05	340	51	6	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 OR2A2	1.09e-05	343	51	6	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 OR2A2	1.15e-05	346	51	6	14611657
Pubmed	Brain expression of Kv3 subunits during development, adulthood and aging and in a murine model of Alzheimer's disease.	KCNC1 KCNC2	1.26e-05	4	51	2	21912965
Pubmed	A zonal organization of odorant receptor gene expression in the olfactory epithelium.	OR2A7 OR2A4	1.26e-05	4	51	2	7683976
Pubmed	G protein beta interacts with the glucocorticoid receptor and suppresses its transcriptional activity in the nucleus.	GNB1 GNB2	1.26e-05	4	51	2	15955845
Pubmed	Ablation of the GNB3 gene in mice does not affect body weight, metabolism or blood pressure, but causes bradycardia.	GNB1 GNB3	1.26e-05	4	51	2	25093805
Pubmed	Localization of Shaw-related K+ channel genes on mouse and human chromosomes.	KCNC1 KCNC2	1.26e-05	4	51	2	8111118
Pubmed	G protein subunit G gamma 13 is coexpressed with G alpha o, G beta 3, and G beta 4 in retinal ON bipolar cells.	GNB4 GNB3	1.26e-05	4	51	2	12454992
Pubmed	Gbeta gamma isoforms selectively rescue plasma membrane localization and palmitoylation of mutant Galphas and Galphaq.	GNB4 GNB1	2.10e-05	5	51	2	11294873
Pubmed	Mitogen-activated protein kinase activation requires two signal inputs from the human anaphylatoxin C5a receptor.	GNB1 GNB2	2.10e-05	5	51	2	7649993
Pubmed	Intersubunit surfaces in G protein alpha beta gamma heterotrimers. Analysis by cross-linking and mutagenesis of beta gamma.	GNB1 GNB3	2.10e-05	5	51	2	8550614
Pubmed	Localization of the gene for a third G protein beta-subunit to mouse chromosome 6 near Raf-1.	GNB1 GNB3	2.10e-05	5	51	2	1572642
Pubmed	Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.	GNB1 GNB2	3.15e-05	6	51	2	9238069
Pubmed	Isolation of cDNA clones encoding eight different human G protein gamma subunits, including three novel forms designated the gamma 4, gamma 10, and gamma 11 subunits.	GNB1 GNB2	3.15e-05	6	51	2	7665596
Pubmed	Integral and associated lysosomal membrane proteins.	GNB4 GNB1 GNB2 PGAP6	3.60e-05	126	51	4	17897319
Pubmed	Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.	GNB4 GNB1 GNB2 GNB3 ZRANB1	3.91e-05	259	51	5	9811942
Pubmed	Heteromultimeric delayed-rectifier K+ channels in schwann cells: developmental expression and role in cell proliferation.	KCNC1 KCNC2	4.41e-05	7	51	2	9852577
Pubmed	Saturation mutagenesis defines novel mouse models of severe spine deformity.	OR2A7 OR2A4	5.87e-05	8	51	2	34142127
Pubmed	M-CSF induces the stable interaction of cFms with alphaVbeta3 integrin in osteoclasts.	PHKA2 CSF1R	5.87e-05	8	51	2	16600665
Pubmed	Ataxin 10 induces neuritogenesis via interaction with G-protein beta2 subunit.	GNB1 GNB2	7.54e-05	9	51	2	16498633
Pubmed	Knockout mouse models reveal the contributions of G protein subunits to complement C5a receptor-mediated chemotaxis.	GNB1 GNB2	1.15e-04	11	51	2	32332099
Pubmed	Developmental expression of heterotrimeric G-proteins in the murine cerebellar cortex.	GNB1 GNB2	1.15e-04	11	51	2	11685543
Pubmed	Conditional stimulation of type V and VI adenylyl cyclases by G protein betagamma subunits.	GNB1 GNB2	1.38e-04	12	51	2	17110384
Pubmed	The human G protein beta4 subunit: gene structure, expression, Ggamma and effector interaction.	GNB4 GNB1	1.63e-04	13	51	2	12782285
Pubmed	Comparative analysis of the gene-dense ACHE/TFR2 region on human chromosome 7q22 with the orthologous region on mouse chromosome 5.	ZAN GNB2	1.63e-04	13	51	2	11239002
Pubmed	Evolution of odorant receptors expressed in mammalian testes.	OR2A7 OR2A4	1.63e-04	13	51	2	11014824
Pubmed	Information coding in the olfactory system: evidence for a stereotyped and highly organized epitope map in the olfactory bulb.	OR2A7 OR2A4	1.90e-04	14	51	2	7528109
Pubmed	Large-scale sequencing of two regions in human chromosome 7q22: analysis of 650 kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes.	ZAN GNB2	1.90e-04	14	51	2	9799793
Pubmed	Interaction of G-protein βγ complex with chromatin modulates GPCR-dependent gene regulation.	GNB1 GNB2	2.19e-04	15	51	2	23326349
Pubmed	Analysis of substrate specificity of human DHHC protein acyltransferases using a yeast expression system.	ZDHHC12 ZDHHC8	2.50e-04	16	51	2	23034182
Pubmed	High-resolution comparative mapping of mouse chromosome 17.	TCTE1 LPA	2.50e-04	16	51	2	8406442
Pubmed	Genetic variants associated with disordered eating.	ZDHHC12 CSMD1 NT5C1B	2.51e-04	83	51	3	23568457
Pubmed	Expression profile analysis of vulnerable CA1 pyramidal neurons in young-Middle-Aged Ts65Dn mice.	GNB4 GNB1 GNB3	2.70e-04	85	51	3	25131634
Pubmed	A subset of mouse colonic goblet cells expresses the bitter taste receptor Tas2r131.	GNB1 GNB3	2.83e-04	17	51	2	24367558
Pubmed	DEFOG: a practical scheme for deciphering families of genes.	OR2A14 OR2A7 OR2A12 OR2A2	3.03e-04	219	51	4	12213199
Pubmed	Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.	KCNC2 DGKE GNB1 GNB2 ZDHHC8	3.16e-04	405	51	5	38187761
Pubmed	The cell-intrinsic requirement of Sox6 for cortical interneuron development.	KCNC1 KCNC2	3.18e-04	18	51	2	19709629
Pubmed	Inferring nonneutral evolution from human-chimp-mouse orthologous gene trios.	POLE CSMD1	3.55e-04	19	51	2	14671302
Pubmed	Intracellular localization and tissue-specific distribution of human and yeast DHHC cysteine-rich domain-containing proteins.	ZDHHC12 ZDHHC8	3.94e-04	20	51	2	16647879
Pubmed	Perturbation of the mutated EGFR interactome identifies vulnerabilities and resistance mechanisms.	GNB4 GNB1 GNB2 GNB3	5.46e-04	256	51	4	24189400
Pubmed	Chromosomal localization of genes encoding guanine nucleotide-binding protein subunits in mouse and human.	GNB1 GNB2	5.70e-04	24	51	2	2902634
Pubmed	Evidence for association of GABA(B) receptors with Kir3 channels and regulators of G protein signalling (RGS4) proteins.	GNB2 GNB3	6.19e-04	25	51	2	17185339
Pubmed	Two Distinct Types of E3 Ligases Work in Unison to Regulate Substrate Ubiquitylation.	KLHL25 POLE GNB4	7.39e-04	120	51	3	27565346
Pubmed	Purification and identification of G protein-coupled receptor protein complexes under native conditions.	GNB4 GNB1	9.54e-04	31	51	2	17215244
Pubmed	Role of Elavl-like RNA-binding protein in retinal development and signal transduction.	GNB1 GNB3	9.54e-04	31	51	2	39307290
Pubmed	Retinoid-related orphan nuclear receptor RORbeta is an early-acting factor in rod photoreceptor development.	GNB1 GNB3	1.02e-03	32	51	2	19805139
Pubmed	The giant spectrin βV couples the molecular motors to phototransduction and Usher syndrome type I proteins along their trafficking route.	GNB1 GNB3	1.02e-03	32	51	2	23704327
Pubmed	Genome-wide association study of lung function decline in adults with and without asthma.	CSMD1 MUSK	1.02e-03	32	51	2	22424883
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	KLHL25 POLE PIEZO1 MTMR3 ZZEF1 ZDHHC8 PLEKHH3	1.10e-03	1105	51	7	35748872
Pubmed	The human olfactory receptor gene family.	OR2A14 OR2A7 OR2A12 OR2A4 OR2A2	1.16e-03	541	51	5	14983052
Pubmed	New application of intelligent agents in sporadic amyotrophic lateral sclerosis identifies unexpected specific genetic background.	LPA GNB3	1.22e-03	35	51	2	18513389
Pubmed	The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.	CSF1R GNB4 GNB1 GNB2	1.37e-03	328	51	4	23398456
Interaction	GNGT2 interactions	GNB4 GNB1 GNB2 GNB3	1.27e-08	12	47	4	int:GNGT2
Interaction	GNG11 interactions	GNB4 GNB1 GNB2 GNB3	6.04e-08	17	47	4	int:GNG11
Interaction	RGS6 interactions	GNB4 GNB1 GNB2 GNB3	7.76e-08	18	47	4	int:RGS6
Interaction	GNG7 interactions	GNB4 GNB1 GNB2 GNB3	1.22e-07	20	47	4	int:GNG7
Interaction	GNG3 interactions	GNB4 GNB1 GNB2 GNB3	2.67e-07	24	47	4	int:GNG3
Interaction	GNG4 interactions	GNB4 GNB1 GNB2 GNB3	3.17e-07	25	47	4	int:GNG4
Interaction	GNGT1 interactions	GNB4 GNB1 GNB2 GNB3	3.74e-07	26	47	4	int:GNGT1
Interaction	GNG2 interactions	GNB4 GNB1 GNB2 GNB3 ZRANB1	7.39e-07	73	47	5	int:GNG2
Interaction	GNG5 interactions	GNB4 GNB1 GNB2 GNB3 ZRANB1	1.17e-06	80	47	5	int:GNG5
Interaction	GNG13 interactions	GNB4 GNB1 GNB2 GNB3	2.47e-06	41	47	4	int:GNG13
Interaction	GNG10 interactions	GNB4 GNB1 GNB2 GNB3	3.00e-06	43	47	4	int:GNG10
Interaction	KCTD2 interactions	GNB4 GNB1 GNB2 ZRANB1	8.12e-06	55	47	4	int:KCTD2
Interaction	MTOR interactions	DPEP1 ARSL MTMR3 GNB1 GNB2 GNB3 ZRANB1	1.52e-05	349	47	7	int:MTOR
Interaction	GNAQ interactions	GNB4 GNB1 GNB2 GNB3 PTGIR	1.53e-05	135	47	5	int:GNAQ
Interaction	KCNC2 interactions	KCNC1 KCNC2	1.59e-05	3	47	2	int:KCNC2
Interaction	GNAI3 interactions	GNB4 GNB1 GNB2 GNB3 ZRANB1 PLEKHH3	1.96e-05	241	47	6	int:GNAI3
Interaction	RASD2 interactions	GNB1 GNB2 GNB3	2.64e-05	25	47	3	int:RASD2
Interaction	GNAI1 interactions	GNB4 GNB1 GNB2 GNB3 PTGIR	4.77e-05	171	47	5	int:GNAI1
Interaction	KCTD5 interactions	GNB4 GNB1 GNB2 ZRANB1	7.67e-05	97	47	4	int:KCTD5
Interaction	GNG12 interactions	GNB4 GNB1 GNB2 GNB3	1.44e-04	114	47	4	int:GNG12
Interaction	GNA11 interactions	GNB4 GNB1 GNB2 PTGIR	1.59e-04	117	47	4	int:GNA11
Interaction	MGST1 interactions	GNB4 GNB1 GNB2 ZRANB1	1.98e-04	124	47	4	int:MGST1
Interaction	GNG8 interactions	GNB4 GNB1 GNB2 GNB3	2.05e-04	125	47	4	int:GNG8
Cytoband	7q35	OR2A14 OR2A7 OR2A12 OR2A25 OR2A2	4.61e-09	55	51	5	7q35
Cytoband	Ensembl 112 genes in cytogenetic band chr7q35	OR2A14 OR2A7 OR2A12 OR2A25 OR2A2	1.17e-08	66	51	5	chr7q35
Cytoband	7q22	ZAN GNB2	8.29e-04	38	51	2	7q22
Cytoband	16q24.3	DPEP1 PIEZO1	1.55e-03	52	51	2	16q24.3
GeneFamily	Olfactory receptors, family 2	OR2A14 OR2A7 OR2A12 OR2A4 OR2A25 OR2A2	8.72e-08	113	36	6	149
GeneFamily	Zinc fingers DHHC-type\|Ankyrin repeat domain containing	ZDHHC12 ZDHHC8	1.03e-03	24	36	2	76
GeneFamily	WD repeat domain containing	GNB4 GNB1 GNB2 GNB3	1.76e-03	262	36	4	362
GeneFamily	Potassium voltage-gated channels	KCNC1 KCNC2	2.87e-03	40	36	2	274
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	CSF1R MUSK	2.87e-03	40	36	2	321
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SRPX2 CSMD1	5.74e-03	57	36	2	1179
Coexpression	GSE10422_WT_VS_BAFF_TRANSGENIC_LN_BCELL_UP	MTMR3 IRF2BPL GNB4 ZDHHC8 ZRANB1	1.95e-05	180	48	5	M357
Coexpression	GSE369_PRE_VS_POST_IL6_INJECTION_SOCS3_KO_LIVER_DN	CSF1R POLE NAGPA ZZEF1 PTGIR	3.23e-05	200	48	5	M5977
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRN3 SRPX2 PTGIR PRDM6 MUSK	2.90e-06	195	51	5	4243190ad291d56694e2155954dbaa879c9d3844
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRN3 SRPX2 PTGIR PRDM6 MUSK	2.90e-06	195	51	5	df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LRRN3 SRPX2 PTGIR PRDM6 MUSK	2.98e-06	196	51	5	42e9828222a9663525d571633e8a454c30bfa7f8
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	KCNC1 KCNC2 NSUN7 DNMT3L	1.32e-05	126	51	4	84dce108561d4b745d19250c2ac0667d9e4ea17d
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_2\|368C / Donor, Lineage, Cell class and subclass (all cells)	CSF1R POLE PIEZO1 ZDHHC8	4.38e-05	171	51	4	26b34dc069cc15b75a0c13cb8c5d81e074788160
ToppCell	droplet-Marrow-nan-18m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF1R MAP4K3 ZZEF1 ZDHHC8	4.69e-05	174	51	4	55cc8300489d11322724159ec7d0e1d32a702e91
ToppCell	droplet-Fat-Bat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD1 ZDHHC8 PTGIR PRDM6	4.79e-05	175	51	4	b4f01e7782cdd107d0817ef601891fd3a382bc35
ToppCell	droplet-Fat-Bat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD1 ZDHHC8 PTGIR PRDM6	4.79e-05	175	51	4	ef6f811d8e1839f405c3b41090ddf79be57a099f
ToppCell	droplet-Fat-Bat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSMD1 ZDHHC8 PTGIR PRDM6	4.79e-05	175	51	4	7f7598d46d10bff1cbea42f950bdde1aaa16e9a4
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	SRPX2 PTGIR PRDM6 MUSK	7.29e-05	195	51	4	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Tracheal-10x3prime_v2-Epithelial-Epi_airway_neuro-secretory-Ionocyte_n_Brush\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PHKA2 KCNC1 MTMR3 PGAP6	7.73e-05	198	51	4	62059185afdf66126a6fbc899ce611c47e7a0feb
ToppCell	distal-1-mesenchymal-Alveolar_Fibroblast\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LRRN3 SRPX2 PTGIR MUSK	7.73e-05	198	51	4	6594c35ab203dc51462167c61807b0d49fa30fb2
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LRRN3 SRPX2 PTGIR MUSK	7.73e-05	198	51	4	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Myofibroblasts\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	LRRN3 SRPX2 PRDM6 MUSK	7.89e-05	199	51	4	7a227c239afdaebcac84644d9b2653a5f1a4be71
ToppCell	distal-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LRRN3 SRPX2 PTGIR MUSK	8.04e-05	200	51	4	12b705dabec1b3752a488a891eda1a5123fcdc41
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	TCTE1 DPEP1 DENND4A PIEZO1	8.04e-05	200	51	4	5c638c80661017c85f9390f1b398ac7728c8f001
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	LRRN3 SRPX2 PTGIR MUSK	8.04e-05	200	51	4	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	LRRN3 SRPX2 PTGIR MUSK	8.04e-05	200	51	4	a510deaada669e690329183e18df02870bd204b3
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LRRN3 SRPX2 PTGIR MUSK	8.04e-05	200	51	4	dd4228cbed8a4395166a6332e08d44d88bebe3b9
Disease	serum albumin measurement	DPEP1 MAP4K3 LPA IRF2BPL ZZEF1 NSUN7	3.39e-04	592	47	6	EFO_0004535
Disease	lung cancer	CSMD1 ZRANB1	5.12e-04	21	47	2	MONDO_0008903
Disease	total blood protein measurement	CSF1R MAP4K3 DGKE MUSK NSUN7	7.23e-04	449	47	5	EFO_0004536
Disease	alpha-linolenic acid measurement	CSMD1 MUSK	7.28e-04	25	47	2	EFO_0007759
Disease	hematocrit	DPEP1 ZAN PIEZO1 MTMR3 GNB2 PGAP6 MUSK	1.03e-03	1011	47	7	EFO_0004348
Disease	serum IgA measurement	MTMR3 MUSK	1.12e-03	31	47	2	EFO_0004912
Disease	aortic stenosis	LPA MUSK	1.12e-03	31	47	2	EFO_0000266
Disease	cholesteryl ester 22:6 measurement	CSMD1 MUSK	1.19e-03	32	47	2	EFO_0010350
Disease	uridine measurement	KLHL25 CSMD1	1.19e-03	32	47	2	EFO_0010546
Disease	Squamous cell carcinoma of lung	CSF1R MAP4K3	1.19e-03	32	47	2	C0149782
Disease	word list delayed recall measurement, memory performance	CHD6 ADA2	1.27e-03	33	47	2	EFO_0004874, EFO_0006805

Protein segments in the cluster

Peptide	Gene	Start	Entry
PCHTIRIYIHMCLLW	NT5C1B	76	Q96P26
HSCLCFRSWLPAMLA	ARSL	6	P51690
SHISCMPGTVRRWNY	CSMD1	1951	Q96PZ7
AMSNWVCYLCLPSSR	DNMT3L	136	Q9UJW3
IPQMWSRCLLRHCYG	DENND4A	756	Q7Z401
DSENYWLRCCMHRWP	TCTE1	126	Q5JU00
PRRCTWLYVMNNCLL	MAP4K3	601	Q8IVH8
CHPLQYTLIMNWRVC	OR2A12	126	Q8NGT7
CHPLRYNSLMSWRVC	OR2A14	126	Q96R47
TDVEPCCWMTYRQHR	KCNC2	146	Q96PR1
RQSCYLCDLPRMPWA	IRF2BPL	11	Q9H1B7
PSTLWCHCRQVYLPM	LSS	226	P48449
HAIPLRSSWVMTCAY	GNB2	91	P62879
HAIPLRSSWVMTCAY	GNB3	91	P16520
HAIPLRSSWVMTCAY	GNB4	91	Q9HAV0
EYKAPQCIHMDCLRW	POLE	396	Q07864
CCVLRYMVQWPGARI	FAM120A	716	Q9NZB2
SMWAYRCGHRRQCYP	PGAP6	671	Q9HCN3
CHPLRYLAIMTWRVC	OR2A7	126	Q96R45
CHPFQYTVIMSWRVC	OR2A2	126	Q6IF42
CHPLRYLAIMTWRVC	OR2A4	126	O95047
SWMRYIRCARHCGEQ	PRDM6	321	Q9NQX0
YSIMQACWALEPTHR	CSF1R	886	P07333
CRRLYEFSWRMCLVH	KLHL25	161	Q9H0H3
VEPCCWMTYRQHRDA	KCNC1	101	P48547
HAIPLRSSWVMTCAY	GNB1	91	P62873
SFVAMCRNVCRLPTW	CHD6	1501	Q8TD26
MDWLVRNVTYRPHCH	ADA2	121	Q9NZK5
MDPSVRWEYCNLTRC	LPA	1451	P08519
CSHVPMWSARLLTCR	CRIPAK	241	Q8N1N5
CSHVPMWSARLLTCR	CRIPAK	261	Q8N1N5
HWIRGNVPLCSYCMV	DGKE	126	P52429
WILTARQCFSSCHMP	MST1	516	P26927
SLSHNYRICCWKMVP	C5orf34	426	Q96MH7
MRYLTLTHSCNTPWA	DPEP1	161	P16444
RHSILSNWCYVLPSM	C18orf63	191	Q68DL7
ELAYLCTCWRMTGRP	PHKA2	546	P46019
YPVCHVRNLMLWSAV	MTMR3	561	Q13615
CHPLRYSVIMTWRVC	OR2A1;	126	Q8NGT9
CHPLRYSTIMTWKVC	OR2A25	126	A4D2G3
RYWQLLTCMSCTFRP	PLEKHH3	331	Q7Z736
HSNPIRCDCVIRWMN	LRRN3	366	Q9H3W5
IRSRMPTQHLYCRWV	NSUN7	666	Q8NE18
MWRCPRQVSTVVCVH	NAGPA	311	Q9UK23
WSGTAYCRQMRCHAL	SRPX2	111	O60687
HQQYCPGSWCFLRMR	PTGIR	161	P43119
RHGTRCTVPWYVMTS	UAP1L1	156	Q3KQV9
PWHRYRCLQCSDMDL	ZZEF1	1791	O43149
VRMKWCATCHFYRPP	ZDHHC8	101	Q9ULC8
TLCCLRYVWAMDLRP	PIEZO1	476	Q92508
CRRCVRRYDHHCPWM	ZDHHC12	116	Q96GR4
HMCTYLNWPRAIRCT	ZRANB1	91	Q9UGI0
MGTCTYVLTRPCWSR	ZAN	1561	Q9Y493
NCPVELYNLMRLCWS	MUSK	826	O15146