Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cyclin-dependent protein kinase activity	CDK8 CDK1 CDK19	1.21e-05	30	30	3	GO:0097472
GeneOntologyMolecularFunction	cyclin-dependent protein serine/threonine kinase activity	CDK8 CDK1 CDK19	1.21e-05	30	30	3	GO:0004693
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ZNF195 ZNF479 ZNF716 ZNF586 RARA RARB SMAD1 SMAD5 NR2E1	5.95e-05	1244	30	9	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	ZNF195 ZNF479 ZNF716 ZNF586 RARA RARB SMAD1 SMAD5 NR2E1	7.03e-05	1271	30	9	GO:0000987
GeneOntologyMolecularFunction	DEAD/H-box RNA helicase binding	SMAD1 SMAD5	7.80e-05	9	30	2	GO:0017151
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat kinase activity	CDK8 CDK1	9.75e-05	10	30	2	GO:0008353
GeneOntologyMolecularFunction	nuclear receptor activity	RARA RARB NR2E1	9.88e-05	60	30	3	GO:0004879
GeneOntologyMolecularFunction	ligand-activated transcription factor activity	RARA RARB NR2E1	1.04e-04	61	30	3	GO:0098531
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	ZNF195 ZNF479 ZNF716 ZNF586 RARA RARB SMAD1 SMAD5 NR2E1	1.58e-04	1412	30	9	GO:0000981
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	ZNF195 ZNF479 ZNF716 ZNF586 RARA RARB SMAD1 SMAD5 NR2E1	2.03e-04	1459	30	9	GO:0000977
GeneOntologyMolecularFunction	I-SMAD binding	SMAD1 SMAD5	2.93e-04	17	30	2	GO:0070411
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat modifying activity	CDK8 CDK1	5.41e-04	23	30	2	GO:0140994
GeneOntologyMolecularFunction	protein kinase activity	CDK8 CDK1 ABL1 TSSK4 CDK19	1.84e-03	600	30	5	GO:0004672
GeneOntologyMolecularFunction	protein serine kinase activity	CDK8 CDK1 TSSK4 CDK19	2.03e-03	363	30	4	GO:0106310
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	CDK8 CDK1 ABL1 TSSK4 CDK19	3.79e-03	709	30	5	GO:0016773
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	CDK8 CDK1 TSSK4 CDK19	4.25e-03	446	30	4	GO:0004674
GeneOntologyMolecularFunction	kinase activity	CDK8 CDK1 ABL1 TSSK4 CDK19	5.21e-03	764	30	5	GO:0016301
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides	NDST3 PM20D2	6.57e-03	81	30	2	GO:0016811
GeneOntologyBiologicalProcess	ventricular cardiac muscle cell differentiation	CDK1 RARA RARB	2.39e-06	19	29	3	GO:0055012
GeneOntologyBiologicalProcess	cardiac muscle tissue development	CDK1 ABL1 RARA RARB SMAD1 SMAD5	5.30e-06	327	29	6	GO:0048738
GeneOntologyBiologicalProcess	striated muscle tissue development	CDK1 ABL1 RARA RARB SMAD1 SMAD5	7.69e-06	349	29	6	GO:0014706
GeneOntologyBiologicalProcess	ureteric bud development	RARA RARB SMAD1 SMAD5	1.47e-05	107	29	4	GO:0001657
GeneOntologyBiologicalProcess	mesonephric tubule development	RARA RARB SMAD1 SMAD5	1.64e-05	110	29	4	GO:0072164
GeneOntologyBiologicalProcess	mesonephric epithelium development	RARA RARB SMAD1 SMAD5	1.64e-05	110	29	4	GO:0072163
GeneOntologyBiologicalProcess	mesonephros development	RARA RARB SMAD1 SMAD5	1.82e-05	113	29	4	GO:0001823
GeneOntologyBiologicalProcess	central nervous system development	LAMB1 ABL1 RARA RARB F2 KCNC2 ADAM23 SMAD1 NR2E1	2.52e-05	1197	29	9	GO:0007417
GeneOntologyBiologicalProcess	organ growth	CDK1 ABL1 RARA RARB SMAD1	2.64e-05	256	29	5	GO:0035265
GeneOntologyBiologicalProcess	osteoblast fate commitment	SMAD1 SMAD5	2.85e-05	6	29	2	GO:0002051
GeneOntologyBiologicalProcess	heart development	SCUBE1 CDK1 ABL1 RARA RARB SMAD1 SMAD5	6.72e-05	757	29	7	GO:0007507
GeneOntologyBiologicalProcess	kidney epithelium development	RARA RARB SMAD1 SMAD5	7.47e-05	162	29	4	GO:0072073
GeneOntologyBiologicalProcess	muscle tissue development	CDK1 ABL1 RARA RARB SMAD1 SMAD5	1.07e-04	558	29	6	GO:0060537
GeneOntologyBiologicalProcess	brain development	LAMB1 ABL1 RARA RARB KCNC2 SMAD1 NR2E1	1.48e-04	859	29	7	GO:0007420
GeneOntologyBiologicalProcess	regulation of cartilage development	RARA RARB SMAD1	1.98e-04	81	29	3	GO:0061035
GeneOntologyBiologicalProcess	cardiac muscle cell proliferation	CDK1 ABL1 SMAD1	2.05e-04	82	29	3	GO:0060038
GeneOntologyBiologicalProcess	head development	LAMB1 ABL1 RARA RARB KCNC2 SMAD1 NR2E1	2.25e-04	919	29	7	GO:0060322
GeneOntologyBiologicalProcess	gliogenesis	LAMB1 CDK1 ABL1 F2 NR2E1	3.19e-04	435	29	5	GO:0042063
GeneOntologyBiologicalProcess	cartilage development	RARA RARB SMAD1 SMAD5	3.54e-04	243	29	4	GO:0051216
GeneOntologyBiologicalProcess	hormone-mediated signaling pathway	RARA RARB LANCL2 NR2E1	3.60e-04	244	29	4	GO:0009755
GeneOntologyBiologicalProcess	regulation of glial cell differentiation	CDK1 F2 NR2E1	4.14e-04	104	29	3	GO:0045685
GeneOntologyBiologicalProcess	astrocyte differentiation	ABL1 F2 NR2E1	4.25e-04	105	29	3	GO:0048708
GeneOntologyBiologicalProcess	negative regulation of astrocyte differentiation	F2 NR2E1	4.33e-04	22	29	2	GO:0048712
GeneOntologyBiologicalProcess	bone development	RARA RARB SMAD1 SMAD5	4.84e-04	264	29	4	GO:0060348
GeneOntologyBiologicalProcess	striated muscle cell proliferation	CDK1 ABL1 SMAD1	4.87e-04	110	29	3	GO:0014855
GeneOntologyBiologicalProcess	response to organic cyclic compound	CDK1 ABL1 RARA KCNC2 SMAD1 SMAD5 NR2E1	4.99e-04	1048	29	7	GO:0014070
GeneOntologyBiologicalProcess	forebrain development	LAMB1 RARA RARB KCNC2 NR2E1	5.44e-04	489	29	5	GO:0030900
GeneOntologyBiologicalProcess	circulatory system development	SCUBE1 CDK1 ABL1 RARA RARB SMAD1 SMAD5 NR2E1	6.37e-04	1442	29	8	GO:0072359
GeneOntologyBiologicalProcess	growth plate cartilage development	RARA RARB	7.57e-04	29	29	2	GO:0003417
GeneOntologyBiologicalProcess	muscle cell differentiation	LAMB1 CDK1 RARA RARB SMAD1	7.90e-04	531	29	5	GO:0042692
GeneOntologyBiologicalProcess	cerebral cortex radial glia-guided migration	LAMB1 NR2E1	8.10e-04	30	29	2	GO:0021801
GeneOntologyBiologicalProcess	telencephalon glial cell migration	LAMB1 NR2E1	8.10e-04	30	29	2	GO:0022030
GeneOntologyBiologicalProcess	response to alcohol	CDK1 RARA KCNC2 LANCL2	9.05e-04	312	29	4	GO:0097305
GeneOntologyBiologicalProcess	cardiac muscle tissue growth	CDK1 ABL1 SMAD1	9.43e-04	138	29	3	GO:0055017
GeneOntologyBiologicalProcess	glial cell differentiation	CDK1 ABL1 F2 NR2E1	1.01e-03	321	29	4	GO:0010001
GeneOntologyBiologicalProcess	telencephalon development	LAMB1 RARA RARB NR2E1	1.14e-03	332	29	4	GO:0021537
GeneOntologyBiologicalProcess	heart growth	CDK1 ABL1 SMAD1	1.15e-03	148	29	3	GO:0060419
GeneOntologyBiologicalProcess	negative regulation of cartilage development	RARA RARB	1.17e-03	36	29	2	GO:0061037
GeneOntologyBiologicalProcess	cell fate commitment	RARA SMAD1 SMAD5 NR2E1	1.22e-03	338	29	4	GO:0045165
GeneOntologyBiologicalProcess	connective tissue development	RARA RARB SMAD1 SMAD5	1.28e-03	343	29	4	GO:0061448
GeneOntologyBiologicalProcess	retinoic acid receptor signaling pathway	RARA RARB	1.30e-03	38	29	2	GO:0048384
GeneOntologyBiologicalProcess	endochondral bone growth	RARA RARB	1.37e-03	39	29	2	GO:0003416
GeneOntologyBiologicalProcess	negative regulation of glial cell differentiation	F2 NR2E1	1.37e-03	39	29	2	GO:0045686
GeneOntologyBiologicalProcess	cellular response to organic cyclic compound	CDK1 ABL1 SMAD1 SMAD5 NR2E1	1.41e-03	605	29	5	GO:0071407
GeneOntologyBiologicalProcess	cardiac conduction system development	SMAD1 SMAD5	1.44e-03	40	29	2	GO:0003161
GeneOntologyBiologicalProcess	response to ethanol	CDK1 RARA KCNC2	1.47e-03	161	29	3	GO:0045471
GeneOntologyBiologicalProcess	columnar/cuboidal epithelial cell differentiation	ABL1 RARA RARB	1.55e-03	164	29	3	GO:0002065
GeneOntologyBiologicalProcess	cerebral cortex radially oriented cell migration	LAMB1 NR2E1	1.59e-03	42	29	2	GO:0021799
GeneOntologyBiologicalProcess	glandular epithelial cell development	RARA RARB	1.66e-03	43	29	2	GO:0002068
GeneOntologyBiologicalProcess	regulation of astrocyte differentiation	F2 NR2E1	1.66e-03	43	29	2	GO:0048710
GeneOntologyBiologicalProcess	kidney development	RARA RARB SMAD1 SMAD5	1.73e-03	372	29	4	GO:0001822
GeneOntologyBiologicalProcess	bone growth	RARA RARB	1.82e-03	45	29	2	GO:0098868
GeneOntologyBiologicalProcess	positive regulation of cation transmembrane transport	ABL1 F2 KCNC2	1.83e-03	174	29	3	GO:1904064
GeneOntologyBiologicalProcess	regulation of hematopoietic progenitor cell differentiation	ABL1 RARA	1.90e-03	46	29	2	GO:1901532
GeneOntologyBiologicalProcess	cardiac muscle cell differentiation	CDK1 RARA RARB	1.93e-03	177	29	3	GO:0055007
GeneOntologyBiologicalProcess	renal system development	RARA RARB SMAD1 SMAD5	1.98e-03	386	29	4	GO:0072001
GeneOntologyBiologicalProcess	cartilage development involved in endochondral bone morphogenesis	RARA RARB	1.98e-03	47	29	2	GO:0060351
GeneOntologyBiologicalProcess	positive regulation of release of sequestered calcium ion into cytosol	ABL1 F2	2.07e-03	48	29	2	GO:0051281
GeneOntologyBiologicalProcess	positive regulation of cell cycle	CDK1 ABL1 RARA NR2E1	2.40e-03	407	29	4	GO:0045787
GeneOntologyBiologicalProcess	positive regulation of monoatomic ion transmembrane transport	ABL1 F2 KCNC2	2.43e-03	192	29	3	GO:0034767
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	CDK8 ABL1 RARA RARB SMAD1 SMAD5 NR2E1	2.61e-03	1390	29	7	GO:0045944
GeneOntologyBiologicalProcess	BMP signaling pathway	ABL1 SMAD1 SMAD5	2.61e-03	197	29	3	GO:0030509
GeneOntologyBiologicalProcess	cerebral cortex cell migration	LAMB1 NR2E1	2.80e-03	56	29	2	GO:0021795
GeneOntologyBiologicalProcess	response to amine	CDK1 KCNC2	3.00e-03	58	29	2	GO:0014075
GeneOntologyCellularComponent	CKM complex	CDK8 CDK19	1.99e-05	5	30	2	GO:1990508
GeneOntologyCellularComponent	heteromeric SMAD protein complex	SMAD1 SMAD5	5.55e-05	8	30	2	GO:0071144
GeneOntologyCellularComponent	SMAD protein complex	SMAD1 SMAD5	8.90e-05	10	30	2	GO:0071141
GeneOntologyCellularComponent	cyclin-dependent protein kinase holoenzyme complex	CDK8 CDK1 CDK19	9.07e-05	61	30	3	GO:0000307
GeneOntologyCellularComponent	nuclear cyclin-dependent protein kinase holoenzyme complex	CDK8 CDK19	3.00e-04	18	30	2	GO:0019908
GeneOntologyCellularComponent	serine/threonine protein kinase complex	CDK8 CDK1 CDK19	1.45e-03	157	30	3	GO:1902554
GeneOntologyCellularComponent	protein kinase complex	CDK8 CDK1 CDK19	1.83e-03	170	30	3	GO:1902911
GeneOntologyCellularComponent	RNA polymerase II transcription regulator complex	RARA SMAD1 SMAD5	6.82e-03	272	30	3	GO:0090575
Domain	GSDH	HHIPL1 HHIPL2	7.48e-06	3	30	2	PF07995
Domain	Glc/Sorbosone_DH	HHIPL1 HHIPL2	7.48e-06	3	30	2	IPR012938
Domain	Retinoic_acid_rcpt	RARA RARB	1.49e-05	4	30	2	IPR003078
Domain	zf-C4	RARA RARB NR2E1	5.42e-05	46	30	3	PF00105
Domain	NUCLEAR_REC_DBD_1	RARA RARB NR2E1	5.42e-05	46	30	3	PS00031
Domain	Znf_hrmn_rcpt	RARA RARB NR2E1	5.42e-05	46	30	3	IPR001628
Domain	Nuclear_hrmn_rcpt	RARA RARB NR2E1	5.42e-05	46	30	3	IPR001723
Domain	ZnF_C4	RARA RARB NR2E1	5.42e-05	46	30	3	SM00399
Domain	NUCLEAR_REC_DBD_2	RARA RARB NR2E1	5.42e-05	46	30	3	PS51030
Domain	-	RARA RARB NR2E1	5.78e-05	47	30	3	1.10.565.10
Domain	HOLI	RARA RARB NR2E1	6.16e-05	48	30	3	SM00430
Domain	Nucl_hrmn_rcpt_lig-bd	RARA RARB NR2E1	6.16e-05	48	30	3	IPR000536
Domain	Hormone_recep	RARA RARB NR2E1	6.16e-05	48	30	3	PF00104
Domain	Dwarfin	SMAD1 SMAD5	6.94e-05	8	30	2	IPR013790
Domain	DWB	SMAD1 SMAD5	6.94e-05	8	30	2	SM00524
Domain	-	SMAD1 SMAD5	6.94e-05	8	30	2	3.90.520.10
Domain	MAD_homology_MH1	SMAD1 SMAD5	6.94e-05	8	30	2	IPR013019
Domain	MH2	SMAD1 SMAD5	6.94e-05	8	30	2	PS51076
Domain	MH1	SMAD1 SMAD5	6.94e-05	8	30	2	PS51075
Domain	Folate_rcpt-like	HHIPL1 HHIPL2	6.94e-05	8	30	2	IPR018143
Domain	MH2	SMAD1 SMAD5	6.94e-05	8	30	2	PF03166
Domain	SMAD_dom_Dwarfin-type	SMAD1 SMAD5	6.94e-05	8	30	2	IPR001132
Domain	Folate_rec	HHIPL1 HHIPL2	6.94e-05	8	30	2	PF03024
Domain	-	RARA RARB NR2E1	1.03e-04	57	30	3	3.30.50.10
Domain	Znf_NHR/GATA	RARA RARB NR2E1	1.09e-04	58	30	3	IPR013088
Domain	MAD_homology1_Dwarfin-type	SMAD1 SMAD5	1.63e-04	12	30	2	IPR003619
Domain	DWA	SMAD1 SMAD5	1.63e-04	12	30	2	SM00523
Domain	MH1	SMAD1 SMAD5	1.63e-04	12	30	2	PF03165
Domain	Quinoprot_gluc/sorb_DH	HHIPL1 HHIPL2	1.63e-04	12	30	2	IPR011041
Domain	SMAD_dom-like	SMAD1 SMAD5	2.95e-04	16	30	2	IPR017855
Domain	-	SMAD1 SMAD5	2.95e-04	16	30	2	2.60.200.10
Domain	Protein_kinase_ATP_BS	CDK8 CDK1 ABL1 TSSK4 CDK19	3.14e-04	379	30	5	IPR017441
Domain	Kringle	F2 PRSS12	3.34e-04	17	30	2	IPR000001
Domain	Kringle	F2 PRSS12	3.34e-04	17	30	2	PF00051
Domain	KRINGLE_1	F2 PRSS12	3.34e-04	17	30	2	PS00021
Domain	Kringle_CS	F2 PRSS12	3.34e-04	17	30	2	IPR018056
Domain	KR	F2 PRSS12	3.34e-04	17	30	2	SM00130
Domain	KRINGLE_2	F2 PRSS12	3.34e-04	17	30	2	PS50070
Domain	SRCR	HHIPL1 PRSS12	5.14e-04	21	30	2	PF00530
Domain	SR	HHIPL1 PRSS12	7.31e-04	25	30	2	SM00202
Domain	-	HHIPL1 PRSS12	7.31e-04	25	30	2	3.10.250.10
Domain	PROTEIN_KINASE_ATP	CDK8 CDK1 ABL1 TSSK4 CDK19	7.52e-04	459	30	5	PS00107
Domain	SRCR_1	HHIPL1 PRSS12	7.91e-04	26	30	2	PS00420
Domain	SRCR-like_dom	HHIPL1 PRSS12	7.91e-04	26	30	2	IPR017448
Domain	SRCR_2	HHIPL1 PRSS12	7.91e-04	26	30	2	PS50287
Domain	SRCR	HHIPL1 PRSS12	8.54e-04	27	30	2	IPR001190
Domain	Prot_kinase_dom	CDK8 CDK1 ABL1 TSSK4 CDK19	1.00e-03	489	30	5	IPR000719
Domain	PROTEIN_KINASE_DOM	CDK8 CDK1 ABL1 TSSK4 CDK19	1.04e-03	493	30	5	PS50011
Domain	Kringle-like	F2 PRSS12	1.20e-03	32	30	2	IPR013806
Domain	Kinase-like_dom	CDK8 CDK1 ABL1 TSSK4 CDK19	1.58e-03	542	30	5	IPR011009
Domain	-	HHIPL1 HHIPL2	1.78e-03	39	30	2	2.120.10.30
Domain	BTB-kelch_protein	KLHL14 KLHL23	2.16e-03	43	30	2	IPR017096
Domain	Ser/Thr_kinase_AS	CDK8 CDK1 TSSK4 CDK19	2.43e-03	357	30	4	IPR008271
Domain	KRAB	ZNF195 ZNF479 ZNF716 ZNF586	2.45e-03	358	30	4	PS50805
Domain	KRAB	ZNF195 ZNF479 ZNF716 ZNF586	2.45e-03	358	30	4	PF01352
Domain	6-blade_b-propeller_TolB-like	HHIPL1 HHIPL2	2.47e-03	46	30	2	IPR011042
Domain	S_TKc	CDK8 CDK1 TSSK4 CDK19	2.48e-03	359	30	4	SM00220
Domain	PROTEIN_KINASE_ST	CDK8 CDK1 TSSK4 CDK19	2.55e-03	362	30	4	PS00108
Domain	KRAB	ZNF195 ZNF479 ZNF716 ZNF586	2.74e-03	369	30	4	SM00349
Domain	KRAB	ZNF195 ZNF479 ZNF716 ZNF586	2.76e-03	370	30	4	IPR001909
Domain	BTB	KLHL14 KCNC2 KLHL23	2.95e-03	180	30	3	SM00225
Domain	Pkinase	CDK8 CDK1 TSSK4 CDK19	3.07e-03	381	30	4	PF00069
Domain	SMAD_FHA_domain	SMAD1 SMAD5	3.15e-03	52	30	2	IPR008984
Domain	BTB/POZ_dom	KLHL14 KCNC2 KLHL23	3.19e-03	185	30	3	IPR000210
Domain	SKP1/BTB/POZ	KLHL14 KCNC2 KLHL23	3.39e-03	189	30	3	IPR011333
Domain	Kelch-typ_b-propeller	KLHL14 KLHL23	3.51e-03	55	30	2	IPR015915
Domain	Kelch	KLHL14 KLHL23	3.90e-03	58	30	2	SM00612
Domain	Gal_Oxase/kelch_b-propeller	KLHL14 KLHL23	4.03e-03	59	30	2	IPR011043
Domain	BACK	KLHL14 KLHL23	4.17e-03	60	30	2	SM00875
Domain	BACK	KLHL14 KLHL23	4.30e-03	61	30	2	PF07707
Domain	BACK	KLHL14 KLHL23	4.30e-03	61	30	2	IPR011705
Domain	Kelch_1	KLHL14 KLHL23	5.63e-03	70	30	2	PF01344
Domain	Kelch_1	KLHL14 KLHL23	5.63e-03	70	30	2	IPR006652
Domain	EGF	LAMB1 SCUBE1 ADAM23	6.21e-03	235	30	3	SM00181
Domain	EGF-like_dom	LAMB1 SCUBE1 ADAM23	7.29e-03	249	30	3	IPR000742
Domain	EGF_1	LAMB1 SCUBE1 ADAM23	7.78e-03	255	30	3	PS00022
Pathway	WP_MARKERS_OF_KIDNEY_CELL_LINEAGE	RARA RARB SMAD1 SMAD5	2.76e-06	59	24	4	M46460
Pathway	REACTOME_RNA_POLYMERASE_II_TRANSCRIPTION	CDK8 ZNF195 ZNF479 ZNF716 ZNF586 CDK1 ABL1 RARA RARB SMAD1 NR2E1	5.98e-06	1387	24	11	M734
Pathway	PID_RETINOIC_ACID_PATHWAY	CDK1 RARA RARB	1.71e-05	30	24	3	M207
Pathway	REACTOME_GENERIC_TRANSCRIPTION_PATHWAY	CDK8 ZNF195 CDK1 ABL1 RARA RARB SMAD1 NR2E1	2.52e-05	768	24	8	MM14851
Pathway	WP_NUCLEAR_RECEPTORS	RARA RARB NR2E1	3.52e-05	38	24	3	M39657
Pathway	WP_NUCLEAR_RECEPTORS	RARA RARB NR2E1	3.52e-05	38	24	3	MM15865
Pathway	WP_VITAMIN_A1_AND_A5X_PATHWAYS	RARA RARB	4.15e-05	6	24	2	M48097
Pathway	KEGG_MEDICUS_REFERENCE_BMP15_SIGNALING_PATHWAY	SMAD1 SMAD5	5.80e-05	7	24	2	M47845
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	RARA RARB NR2E1	7.13e-05	48	24	3	MM14987
Pathway	KEGG_MEDICUS_REFERENCE_MYOSTATIN_SIGNALING_PATHWAY	SMAD1 SMAD5	7.73e-05	8	24	2	M47847
Pathway	REACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY	RARA RARB NR2E1	9.61e-05	53	24	3	M8276
Pathway	KEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY	SMAD1 SMAD5	9.93e-05	9	24	2	M47844
Pathway	KEGG_MEDICUS_REFERENCE_BMP9_10_SIGNALING_PATHWAY	SMAD1 SMAD5	9.93e-05	9	24	2	M47822
Pathway	WP_DEVELOPMENT_OF_URETERIC_COLLECTION_SYSTEM	RARA RARB SMAD1	1.39e-04	60	24	3	M40048
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	CDK8 RARA SMAD1 SMAD5	1.46e-04	161	24	4	M27871
Pathway	PID_ALK2_PATHWAY	SMAD1 SMAD5	1.51e-04	11	24	2	M203
Pathway	KEGG_MEDICUS_REFERENCE_BMP_HAMP_SIGNALING_PATHWAY	SMAD1 SMAD5	1.51e-04	11	24	2	M47848
Pathway	REACTOME_GENE_EXPRESSION_TRANSCRIPTION	CDK8 ZNF195 CDK1 ABL1 RARA RARB SMAD1 NR2E1	1.91e-04	1022	24	8	MM15436
Pathway	WP_BMP2WNT4FOXO1_PATHWAY_IN_PRIMARY_ENDOMETRIAL_STROMAL_CELL_DIFFERENTIATION	SMAD1 SMAD5	2.14e-04	13	24	2	M39378
Pathway	BIOCARTA_EFP_PATHWAY	CDK8 CDK1	3.29e-04	16	24	2	M22011
Pathway	WP_BMP_SIGNALING_PATHWAY_IN_EYELID_DEVELOPMENT	SMAD1 SMAD5	5.18e-04	20	24	2	MM15907
Pathway	WP_BMP_SIGNALING_IN_EYELID_DEVELOPMENT	SMAD1 SMAD5	5.18e-04	20	24	2	M39624
Pathway	KEGG_MEDICUS_REFERENCE_BMP_SIGNALING_PATHWAY	SMAD1 SMAD5	5.18e-04	20	24	2	M47843
Pathway	BIOCARTA_CTCF_PATHWAY	SMAD1 SMAD5	7.49e-04	24	24	2	M11420
Pathway	BIOCARTA_CTCF_PATHWAY	SMAD1 SMAD5	7.49e-04	24	24	2	MM1373
Pathway	WP_MACROPHAGESTIMULATING_PROTEIN_MSP_SIGNALING	ABL1 SMAD1 SMAD5	7.87e-04	108	24	3	M48078
Pathway	WP_DIFFERENTIATION_OF_WHITE_AND_BROWN_ADIPOCYTE	SMAD1 SMAD5	8.14e-04	25	24	2	M39665
Pathway	REACTOME_ADIPOGENESIS	CDK8 SMAD1 CDK19	8.30e-04	110	24	3	M48259
Pathway	PID_RXR_VDR_PATHWAY	RARA RARB	8.81e-04	26	24	2	M162
Pathway	PID_ALK1_PATHWAY	SMAD1 SMAD5	8.81e-04	26	24	2	M185
Pathway	REACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS	CDK8 SMAD1 SMAD5	1.02e-03	118	24	3	MM15588
Pathway	BIOCARTA_G1_PATHWAY	CDK1 ABL1	1.02e-03	28	24	2	M648
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2	CDK1 ABL1 SMAD1	1.04e-03	119	24	3	M27785
Pathway	BIOCARTA_G1_PATHWAY	CDK1 ABL1	1.10e-03	29	24	2	MM1364
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	RARA RARB	1.17e-03	30	24	2	MM15866
Pathway	REACTOME_SIGNALING_BY_BMP	SMAD1 SMAD5	1.25e-03	31	24	2	M1662
Pathway	REACTOME_SIGNALING_BY_BMP	SMAD1 SMAD5	1.25e-03	31	24	2	MM14789
Pathway	REACTOME_RUNX2_REGULATES_BONE_DEVELOPMENT	ABL1 SMAD1	1.25e-03	31	24	2	M27805
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	RARA RARB	1.42e-03	33	24	2	MM1448
Pathway	WP_CANCER_PATHWAYS	LAMB1 ABL1 RARA RARB F2	1.42e-03	507	24	5	M48302
Pathway	BIOCARTA_NUCLEARRS_PATHWAY	RARA RARB	1.51e-03	34	24	2	M16393
Pathway	WP_NUCLEAR_RECEPTORS_IN_LIPID_METABOLISM_AND_TOXICITY	RARA RARB	1.60e-03	35	24	2	M39488
Pathway	BIOCARTA_ALK_PATHWAY	SMAD1 SMAD5	1.78e-03	37	24	2	M17400
Pathway	WP_NEOVASCULARIZATION_PROCESSES	SMAD1 SMAD5	1.78e-03	37	24	2	M39506
Pathway	REACTOME_DEVELOPMENTAL_BIOLOGY	CDK8 LAMB1 ABL1 RARA RARB ADAM23 SMAD1 CDK19	1.84e-03	1432	24	8	M509
Pathway	KEGG_PATHWAYS_IN_CANCER	LAMB1 ABL1 RARA RARB	2.05e-03	325	24	4	M12868
Pathway	WP_ATM_SIGNALING	CDK1 ABL1	2.08e-03	40	24	2	M39433
Pathway	PID_BMP_PATHWAY	SMAD1 SMAD5	2.29e-03	42	24	2	M181
Pathway	WP_VITAMIN_A_AND_CAROTENOID_METABOLISM	RARA RARB	2.40e-03	43	24	2	M39554
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RARA RARB	2.40e-03	43	24	2	M27443
Pathway	WP_RETINOL_METABOLISM	RARA RARB	2.52e-03	44	24	2	MM15851
Pathway	WP_MICROTUBULE_CYTOSKELETON_REGULATION	CDK1 ABL1	2.99e-03	48	24	2	M39566
Pathway	REACTOME_SIGNALING_BY_RETINOIC_ACID	RARA RARB	3.11e-03	49	24	2	MM15186
Pathway	WP_ID_SIGNALING_PATHWAY	SMAD1 SMAD5	3.24e-03	50	24	2	MM15817
Pathway	WP_TGFBETA_SIGNALING_PATHWAY	SMAD1 SMAD5	3.63e-03	53	24	2	MM15880
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING	SMAD1 SMAD5	3.90e-03	55	24	2	M39351
Pathway	WP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS	SMAD1 SMAD5	4.48e-03	59	24	2	M39886
Pathway	WP_OREXIN_RECEPTOR_PATHWAY	RARA SMAD1 SMAD5	4.57e-03	200	24	3	M48048
Pathway	WP_10Q1121Q1123_COPY_NUMBER_VARIATION_SYNDROME	SMAD1 SMAD5	4.78e-03	61	24	2	M48077
Pathway	REACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX2	CDK1 SMAD1	4.94e-03	62	24	2	MM15521
Pathway	WP_ALPHA_6_BETA_4_INTEGRIN_SIGNALING_PATHWAY	LAMB1 ABL1	5.58e-03	66	24	2	MM15925
Pubmed	Signaling through retinoic acid receptors is essential for mammalian uterine receptivity and decidualization.	RARA RARB SMAD1 SMAD5 GPX3	1.13e-09	55	30	5	34292881
Pubmed	PARP-1 determines specificity in a retinoid signaling pathway via direct modulation of mediator.	CDK8 RARA RARB	9.51e-08	11	30	3	15808511
Pubmed	BMPs are direct triggers of interdigital programmed cell death.	RARB SMAD1 SMAD5	1.27e-07	12	30	3	26826495
Pubmed	Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways.	CDK8 SMAD1 SMAD5	1.65e-07	13	30	3	19914168
Pubmed	Sox2 in the dermal papilla niche controls hair growth by fine-tuning BMP signaling in differentiating hair shaft progenitors.	LAMB1 SMAD1 SMAD5	3.22e-07	16	30	3	23153495
Pubmed	SCUBE3 loss-of-function causes a recognizable recessive developmental disorder due to defective bone morphogenetic protein signaling.	SCUBE1 SMAD1 SMAD5	4.68e-07	18	30	3	33308444
Pubmed	Recurrent RARB Translocations in Acute Promyelocytic Leukemia Lacking RARA Translocation.	RARA RARB	7.19e-07	2	30	2	29921692
Pubmed	Mediator kinase inhibition further activates super-enhancer-associated genes in AML.	CDK8 CDK19	7.19e-07	2	30	2	26416749
Pubmed	CDK8/19 Mediator kinases potentiate induction of transcription by NFκB.	CDK8 CDK19	7.19e-07	2	30	2	28855340
Pubmed	BMP signaling dynamics in embryonic orofacial tissue.	SMAD1 SMAD5	7.19e-07	2	30	2	18446813
Pubmed	Inhibition of Cyclin-Dependent Kinase 8/Cyclin-Dependent Kinase 19 Suppresses Its Pro-Oncogenic Effects in Prostate Cancer.	CDK8 CDK19	7.19e-07	2	30	2	35181333
Pubmed	Effect of localization, length and orientation of chondrocytic primary cilium on murine growth plate organization.	SMAD1 SMAD5	7.19e-07	2	30	2	21723296
Pubmed	Regulatory functions of the Mediator kinases CDK8 and CDK19.	CDK8 CDK19	7.19e-07	2	30	2	30585107
Pubmed	Regulation of the levels of Smad1 and Smad5 in MC3T3-E1 cells by Icariine in vitro.	SMAD1 SMAD5	7.19e-07	2	30	2	24297369
Pubmed	BMP-SMAD Signaling Regulates Lineage Priming, but Is Dispensable for Self-Renewal in Mouse Embryonic Stem Cells.	SMAD1 SMAD5	7.19e-07	2	30	2	26711875
Pubmed	Retinoic acid receptors in normal growth and development.	RARA RARB	7.19e-07	2	30	2	1330302
Pubmed	The transcriptional role of Smads and FAST (FoxH1) in TGFbeta and activin signalling.	SMAD1 SMAD5	7.19e-07	2	30	2	11451566
Pubmed	Pan-Cancer Analysis of the Mediator Complex Transcriptome Identifies CDK19 and CDK8 as Therapeutic Targets in Advanced Prostate Cancer.	CDK8 CDK19	7.19e-07	2	30	2	27678455
Pubmed	Compartment-selective sensitivity of cardiovascular morphogenesis to combinations of retinoic acid receptor gene mutations.	RARA RARB	7.19e-07	2	30	2	9168777
Pubmed	HIV Transcription Is Independent of Mediator Kinases.	CDK8 CDK19	7.19e-07	2	30	2	31044597
Pubmed	CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF.	CDK8 CDK19	7.19e-07	2	30	2	36006697
Pubmed	CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.	CDK8 CDK19	7.19e-07	2	30	2	37378433
Pubmed	Retinoic acid regulates gene expression of retinoic acid receptors alpha, beta and gamma in F9 mouse teratocarcinoma cells.	RARA RARB	7.19e-07	2	30	2	1334013
Pubmed	Biological functional annotation of retinoic acid alpha and beta in mouse liver based on genome-wide binding.	RARA RARB	7.19e-07	2	30	2	24833708
Pubmed	Purification and crystallization of the heterodimeric complex of RARbeta and RXRalpha ligand-binding domains in the active conformation.	RARA RARB	7.19e-07	2	30	2	15159591
Pubmed	Differential phosphorylation of c-Abl in cell cycle determined by cdc2 kinase and phosphatase activity.	CDK1 ABL1	7.19e-07	2	30	2	2183353
Pubmed	Cyclin-Dependent Kinases 8 and 19 Regulate Host Cell Metabolism during Dengue Virus Serotype 2 Infection.	CDK8 CDK19	7.19e-07	2	30	2	32560467
Pubmed	[The significance of expression of isoforms RARa1 and RARa2 in response to medicinal therapy and in evaluation of total survival of patients with primarily detected multiple myeloma].	RARA RARB	7.19e-07	2	30	2	30601638
Pubmed	BMP-SMAD1/5 Signaling Regulates Retinal Vascular Development.	SMAD1 SMAD5	7.19e-07	2	30	2	32210087
Pubmed	Reexpression of retinoic acid receptor (RAR) gamma or overexpression of RAR alpha or RAR beta in RAR gamma-null F9 cells reveals a partial functional redundancy between the three RAR types.	RARA RARB	7.19e-07	2	30	2	7644503
Pubmed	Association between nuclear expression of retinoic acid receptor alpha and beta and clinicopathological features and prognosis of advanced non-small cell lung cancer.	RARA RARB	7.19e-07	2	30	2	27306217
Pubmed	BMP receptor-integrin interaction mediates responses of vascular endothelial Smad1/5 and proliferation to disturbed flow.	SMAD1 SMAD5	7.19e-07	2	30	2	23387849
Pubmed	[Mechanisms of transcriptional regulation upon protein phosphorylation by mediator complexes].	CDK8 CDK19	7.19e-07	2	30	2	20408451
Pubmed	Anticancer effect of retinoic acid via AP-1 activity repression is mediated by retinoic acid receptor alpha and beta in gastric cancer cells.	RARA RARB	7.19e-07	2	30	2	12009305
Pubmed	Identification of target genes for the CDK subunits of the Mediator complex.	CDK8 CDK19	7.19e-07	2	30	2	22117896
Pubmed	Mammalian dwarfins are phosphorylated in response to transforming growth factor beta and are implicated in control of cell growth.	SMAD1 SMAD5	7.19e-07	2	30	2	8799132
Pubmed	β1 integrins regulate cellular behaviour and cardiomyocyte organization during ventricular wall formation.	LAMB1 SMAD1 SMAD5	8.82e-07	22	30	3	38794925
Pubmed	Loss of Sox9 in the periotic mesenchyme affects mesenchymal expansion and differentiation, and epithelial morphogenesis during cochlea development in the mouse.	RARB SMAD1 SMAD5	1.87e-06	28	30	3	20346939
Pubmed	Smad and AML proteins synergistically confer transforming growth factor beta1 responsiveness to human germ-line IgA genes.	SMAD1 SMAD5	2.16e-06	3	30	2	10652350
Pubmed	Function of the retinoic acid receptors (RARs) during development (II). Multiple abnormalities at various stages of organogenesis in RAR double mutants.	RARA RARB	2.16e-06	3	30	2	7607068
Pubmed	Function of the retinoic acid receptors (RARs) during development (I). Craniofacial and skeletal abnormalities in RAR double mutants.	RARA RARB	2.16e-06	3	30	2	7607067
Pubmed	Impaired distribution of retinoic acid receptors in the hindgut-tailgut region of murine embryos with anorectal malformations.	RARA RARB	2.16e-06	3	30	2	11172439
Pubmed	Cloning of several genes coding for retinoic acid nuclear receptors in the mouse embryonal carcinoma cell line PCC7-MZ1.	RARA RARB	2.16e-06	3	30	2	8383767
Pubmed	Non-canonical cyclic AMP SMAD1/5/8 signalling in human granulosa cells.	SMAD1 SMAD5	2.16e-06	3	30	2	30953749
Pubmed	Regulation of BMP4/Dpp retrotranslocation and signaling by deglycosylation.	SMAD1 SMAD5	2.16e-06	3	30	2	32720893
Pubmed	Retinoic acid receptor gamma: specific immunodetection and phosphorylation.	RARA RARB	2.16e-06	3	30	2	1655807
Pubmed	c-Abl-dependent molecular circuitry involving Smad5 and phosphatidylinositol 3-kinase regulates bone morphogenetic protein-2-induced osteogenesis.	ABL1 SMAD5	2.16e-06	3	30	2	23821550
Pubmed	TGF-β uses a novel mode of receptor activation to phosphorylate SMAD1/5 and induce epithelial-to-mesenchymal transition.	SMAD1 SMAD5	2.16e-06	3	30	2	29376829
Pubmed	Mediator complex cooperatively regulates transcription of retinoic acid target genes with Polycomb Repressive Complex 2 during neuronal differentiation.	CDK8 CDK19	2.16e-06	3	30	2	26002960
Pubmed	A redundant oncogenic potential of the retinoic receptor (RAR) alpha, beta and gamma isoforms in acute promyelocytic leukemia.	RARA RARB	2.16e-06	3	30	2	17252005
Pubmed	Retinoic acid down-regulation of fibronectin and retinoic acid receptor alpha proteins in NIH-3T3 cells. Blocks of this response by ras transformation.	RARA RARB	2.16e-06	3	30	2	8626453
Pubmed	Direct visualization of Smad1/5/8-mediated transcriptional activity identifies podocytes and collecting ducts as major targets of BMP signalling in healthy and diseased kidneys.	SMAD1 SMAD5	2.16e-06	3	30	2	21381028
Pubmed	Function of retinoic acid receptor gamma in the mouse.	RARA RARB	2.16e-06	3	30	2	8388780
Pubmed	Contribution of retinoic acid receptor beta isoforms to the formation of the conotruncal septum of the embryonic heart.	RARA RARB	2.16e-06	3	30	2	9659935
Pubmed	Canonical BMP signaling is dispensable for hematopoietic stem cell function in both adult and fetal liver hematopoiesis, but essential to preserve colon architecture.	SMAD1 SMAD5	2.16e-06	3	30	2	20371744
Pubmed	Retinoids and vertebrate development.	RARA RARB	2.16e-06	3	30	2	7910825
Pubmed	Tissue-specific expression of retinoic acid receptor isoform transcripts in the mouse embryo.	RARA RARB	2.16e-06	3	30	2	10842077
Pubmed	Inhibition of histone deacetylase activity by trichostatin A modulates gene expression during mouse embryogenesis without apparent toxicity.	RARA RARB	2.16e-06	3	30	2	11245412
Pubmed	mRNA expression pattern of retinoic acid and retinoid X nuclear receptor subtypes in human thyroid papillary carcinoma.	RARA RARB	2.16e-06	3	30	2	23969901
Pubmed	Altered expression of retinoic acid (RA) receptor mRNAs in the fetal mouse secondary palate by all-trans and 13-cis RAs: implications for RA-induced teratogenesis.	RARA RARB	2.16e-06	3	30	2	10100049
Pubmed	BMP signaling initiates a neural crest differentiation program in embryonic rat CNS stem cells.	SMAD1 SMAD5	2.16e-06	3	30	2	15246821
Pubmed	Differential activation of the murine laminin B1 gene promoter by RAR alpha, ROR alpha, and AP-1.	LAMB1 RARA	2.16e-06	3	30	2	8645318
Pubmed	Both retinoic acid receptors alpha (RARalpha) and gamma (RARgamma) are able to initiate mouse upper-lip skin glandular metaplasia.	RARA RARB	2.16e-06	3	30	2	9699718
Pubmed	Mammalian hexokinase 1: evolutionary conservation and structure to function analysis.	RARA RARB	2.16e-06	3	30	2	1783373
Pubmed	Retinoic acid receptor-beta: immunodetection and phosphorylation on tyrosine residues.	RARA RARB	2.16e-06	3	30	2	1283441
Pubmed	BMP-specific SMADs function as novel repressors of PDGFA and modulate its expression in ovarian granulosa cells and tumors.	SMAD1 SMAD5	2.16e-06	3	30	2	22964636
Pubmed	Abi enhances Abl-mediated CDC2 phosphorylation and inactivation.	CDK1 ABL1	2.16e-06	3	30	2	15591787
Pubmed	Synergistic activation of RARβ and RARγ nuclear receptors restores cell specialization during stem cell differentiation by hijacking RARα-controlled programs.	RARA RARB	2.16e-06	3	30	2	36446525
Pubmed	TGF-β1, but not bone morphogenetic proteins, activates Smad1/5 pathway in primary human macrophages and induces expression of proatherogenic genes.	SMAD1 SMAD5	2.16e-06	3	30	2	25505291
Pubmed	Fluoride promotes viability and differentiation of osteoblast-like Saos-2 cells via BMP/Smads signaling pathway.	SMAD1 SMAD5	2.16e-06	3	30	2	23918166
Pubmed	Smad1 and 5 but not Smad8 establish stem cell quiescence which is critical to transform the premature hair follicle during morphogenesis toward the postnatal state.	SMAD1 SMAD5	2.16e-06	3	30	2	24023003
Pubmed	Characterization of the interaction between retinoic acid receptor/retinoid X receptor (RAR/RXR) heterodimers and transcriptional coactivators through structural and fluorescence anisotropy studies.	RARA RARB	2.16e-06	3	30	2	15528208
Pubmed	Association of retinoic acid receptor genes with meningomyelocele.	RARA RARB	2.16e-06	3	30	2	21254357
Pubmed	Differential expression of TGF-β superfamily members and role of Smad1/5/9-signalling in chondral versus endochondral chondrocyte differentiation.	SMAD1 SMAD5	2.16e-06	3	30	2	27848974
Pubmed	Smad-dependent and smad-independent induction of id1 by prostacyclin analogues inhibits proliferation of pulmonary artery smooth muscle cells in vitro and in vivo.	SMAD1 SMAD5	2.16e-06	3	30	2	20522807
Pubmed	Chromosomal assignment of retinoic acid receptor (RAR) genes in the human, mouse, and rat genomes.	RARA RARB	2.16e-06	3	30	2	1655630
Pubmed	Arg278, but not Lys229 or Lys236, plays an important role in the binding of retinoic acid by retinoic acid receptor gamma.	RARA RARB	2.16e-06	3	30	2	9852056
Pubmed	Ablation of Hepatocyte Smad1, Smad5, and Smad8 Causes Severe Tissue Iron Loading and Liver Fibrosis in Mice.	SMAD1 SMAD5	2.16e-06	3	30	2	31127639
Pubmed	Differential expression of retinoic acid receptors in normal and malignant esophageal tissues.	RARA RARB	2.16e-06	3	30	2	15255287
Pubmed	Activated NF-κB in bone marrow mesenchymal stem cells from systemic lupus erythematosus patients inhibits osteogenic differentiation through downregulating Smad signaling.	SMAD1 SMAD5	2.16e-06	3	30	2	22897816
Pubmed	Heterochromatic gene repression of the retinoic acid pathway in acute myeloid leukemia.	RARA RARB	2.16e-06	3	30	2	17244680
Pubmed	TGFbeta-stimulated Smad1/5 phosphorylation requires the ALK5 L45 loop and mediates the pro-migratory TGFbeta switch.	SMAD1 SMAD5	2.16e-06	3	30	2	19096363
Pubmed	The molecular and genetic dissection of the retinoid signalling pathway.	RARA RARB	2.16e-06	3	30	2	8276261
Pubmed	BMP9 promotes cutaneous wound healing by activating Smad1/5 signaling pathways and cytoskeleton remodeling.	SMAD1 SMAD5	2.16e-06	3	30	2	33463047
Pubmed	Human ovarian cancer cell morphology, motility, and proliferation are differentially influenced by autocrine TGFβ superfamily signalling.	SMAD1 SMAD5	2.16e-06	3	30	2	21945631
Pubmed	Overexpression of Smurf1 negatively regulates mouse embryonic lung branching morphogenesis by specifically reducing Smad1 and Smad5 proteins.	SMAD1 SMAD5	2.16e-06	3	30	2	14711801
Pubmed	Molecular Interaction Between Smurfl WW2 Domain and PPXY Motifs of Smadl, Smad5, and Smad6-Modeling and Analysis.	SMAD1 SMAD5	2.16e-06	3	30	2	22670624
Pubmed	Requirement of retinoic acid receptor isotypes alpha, beta, and gamma during the initial steps of neural differentiation of PCC7 cells.	RARA RARB	2.16e-06	3	30	2	15831518
Pubmed	Immunolocalization of retinoic acid receptors in rat, mouse and human ovary and uterus.	RARA RARB	2.16e-06	3	30	2	8136307
Pubmed	Genes involved in cell adhesion and signaling: a new repertoire of retinoic acid receptor target genes in mouse embryonic fibroblasts.	RARA RARB	2.16e-06	3	30	2	24357724
Pubmed	Erbin plays a critical role in human umbilical vein endothelial cell migration and tubular structure formation via the Smad1/5 pathway.	SMAD1 SMAD5	2.16e-06	3	30	2	30367512
Pubmed	Retinoic acid and mouse skin morphogenesis. I. Expression pattern of retinoic acid receptor genes during hair vibrissa follicle, plantar, and nasal gland development.	RARA RARB	2.16e-06	3	30	2	8027572
Pubmed	Cloning of murine alpha and beta retinoic acid receptors and a novel receptor gamma predominantly expressed in skin.	RARA RARB	2.16e-06	3	30	2	2544807
Pubmed	[Genetic expression and morphogenesis of the skin in vertebrates].	RARA RARB	2.16e-06	3	30	2	8099268
Pubmed	Regulation of retinoic acid receptor alpha by protein kinase C in B16 mouse melanoma cells.	RARA RARB	2.16e-06	3	30	2	12000751
Pubmed	Soy promotes juvenile granulosa cell tumor development in mice and in the human granulosa cell tumor-derived COV434 cell line.	SMAD1 SMAD5	2.16e-06	3	30	2	25165122
Pubmed	Inactivation of menin, the product of the multiple endocrine neoplasia type 1 gene, inhibits the commitment of multipotential mesenchymal stem cells into the osteoblast lineage.	SMAD1 SMAD5	2.16e-06	3	30	2	12649288
Pubmed	Specificity of retinoid receptor gene expression in mouse cervical epithelia.	RARA RARB	2.16e-06	3	30	2	8156902
Pubmed	Characterization of retinoic acid receptor-deficient keratinocytes.	RARA RARB	2.16e-06	3	30	2	10748128
Pubmed	Long-term culture and significant expansion of human Sertoli cells whilst maintaining stable global phenotype and AKT and SMAD1/5 activation.	SMAD1 SMAD5	2.16e-06	3	30	2	25880873
Interaction	MED6 interactions	CDK8 RARA RARB SMAD1 CDK19	3.69e-07	101	30	5	int:MED6
Interaction	RARB interactions	CDK8 RARA RARB RSPH1	6.23e-07	46	30	4	int:RARB
Interaction	MED25 interactions	CDK8 RARA SMAD1 CDK19	1.06e-05	93	30	4	int:MED25
Interaction	CDK8 interactions	CDK8 RARB SMAD1 CDK19 SMAD5	1.77e-05	222	30	5	int:CDK8
Interaction	MED24 interactions	CDK8 SMAD1 CDK19 SMAD5	3.74e-05	128	30	4	int:MED24
Interaction	GDF6 interactions	SMAD1 SMAD5	4.48e-05	7	30	2	int:GDF6
Interaction	ERCC3 interactions	CDK8 RARB SMAD1 SMAD5	1.26e-04	175	30	4	int:ERCC3
Cytoband	Ensembl 112 genes in cytogenetic band chr7p11	ZNF479 ZNF716 LANCL2	2.57e-05	87	30	3	chr7p11
Cytoband	Ensembl 112 genes in cytogenetic band chr4q26	NDST3 PRSS12	6.00e-04	55	30	2	chr4q26
Cytoband	7p11.2	ZNF479 ZNF716	6.90e-04	59	30	2	7p11.2
Cytoband	6q21	CDK19 NR2E1	1.81e-03	96	30	2	6q21
Cytoband	Ensembl 112 genes in cytogenetic band chr6q21	CDK19 NR2E1	2.86e-03	121	30	2	chr6q21
GeneFamily	Cyclin dependent kinases	CDK8 CDK1 CDK19	4.59e-06	26	23	3	496
GeneFamily	Nuclear hormone receptors	RARA RARB NR2E1	3.19e-05	49	23	3	71
GeneFamily	SMAD family	SMAD1 SMAD5	4.31e-05	8	23	2	750
GeneFamily	Cyclins\|Mediator complex	CDK8 CDK19	7.98e-04	33	23	2	1061
GeneFamily	Kelch like\|BTB domain containing	KLHL14 KLHL23	1.29e-03	42	23	2	617
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZNF195 ZNF479 ZNF716 ZNF586	1.20e-02	718	23	4	28
GeneFamily	Basic leucine zipper proteins\|BTB domain containing	KLHL14 KLHL23	1.25e-02	134	23	2	861
Coexpression	KOKKINAKIS_METHIONINE_DEPRIVATION_96HR_UP	ABL1 SMAD1 SMAD5 GPX3	9.77e-06	118	30	4	M12313
Coexpression	KOKKINAKIS_METHIONINE_DEPRIVATION_48HR_UP	CDK1 ABL1 SMAD1 GPX3	1.43e-05	130	30	4	M13537
Coexpression	SENGUPTA_NASOPHARYNGEAL_CARCINOMA_UP	ZNF195 LAMB1 CDK1 ADAM23 PM20D2	2.32e-05	305	30	5	M19875
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RARB KLHL14 KCNC2 GPX3	3.12e-06	151	30	4	090b067873740c282865e2d02cf47d5cb3dd7607
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LAMB1 ZNF479 KLHL23 GPX3	7.43e-06	188	30	4	ccddc08121caff958a2b6f9e278a018858af6b4d
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB1 SCUBE1 LANCL2 GPX3	9.12e-06	198	30	4	d83707b69fb64721ac3cff90ba58cdd999d6b386
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Prdm8\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL14 KCNC2 GPX3	7.31e-05	121	30	3	2ae870f822488799cd0ad85e7f72af64e33a867f
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RARB KLHL14 KCNC2	9.89e-05	134	30	3	657ad905b40ec3f82acdef824431b8276d291ef7
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal-Mature_Fibroblast_2\|E16.5-samps / Age Group, Lineage, Cell class and subclass	RARA KLHL14 GPX3	1.08e-04	138	30	3	05de2cef97c0912fb23f138dd45348f565a14d74
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Gabrg1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	RARB KCNC2 GPX3	1.13e-04	140	30	3	2c44e8cc5190226049be7ebc465d685393e701c4
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Calb1_Sst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NDST3 KCNC2 GPX3	1.27e-04	146	30	3	10839a4fce2e62955a90592f927a6e0c6a84bbad
ToppCell	IIH-CD8-proli_CD4\|IIH / Condition, Cell_class and T cell subcluster	LAMB1 SMAD1 PM20D2	1.27e-04	146	30	3	7fa6e35def3f7cffbee1e1c2f10b523bab678e14
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RARB PRSS12 KLHL23	1.58e-04	157	30	3	ffb8dd381e6b9adc5283fb49586e8bd63773c8d6
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Batf3\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NDST3 SCUBE1 PRSS12	1.58e-04	157	30	3	921805932f7974d37aed547861d555b07f30aba6
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RARB PRSS12 KLHL23	1.58e-04	157	30	3	c488ab1d6c6c7e5c2f4426805d1366b44711a031
ToppCell	Adult-Mesenchymal-chondrocyte\|Adult / Lineage, Cell type, age group and donor	LAMB1 HHIPL1 GPX3	1.64e-04	159	30	3	3f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCell	Int-URO-Lymphocyte-B-Plasmablast\|Int-URO / Disease, Lineage and Cell Type	CDK1 KLHL14 GPX3	1.64e-04	159	30	3	f6ad73b6a3681471efbd4fafd9eb631764c53500
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL14 KCNC2 GPX3	1.70e-04	161	30	3	dccb61d5e17a8f1c6d1fc146ee389f567659a0f0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c02-NCAM1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZNF586 PRSS12 SMAD5	1.76e-04	163	30	3	1c014e373667be290d7fb5d24c06c6f313ac8fa3
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5\|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)	RSPH1 ADAM23 SMAD1	1.93e-04	168	30	3	d7d19c93d1c3dd994e18e28d5f36ae7773ff5d7f
ToppCell	390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	RSPH1 ADAM23 SMAD1	1.96e-04	169	30	3	d2def7229fe9d6b0c70cfed349ede491c8c137a0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RARB PRSS12 GPX3	2.00e-04	170	30	3	3174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-5_RORB_HSPB3\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RARB PRSS12 GPX3	2.00e-04	170	30	3	985c6c9e3c593ed0628a481f06c2c91b2ab5d746
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	KLHL14 KCNC2 GPX3	2.00e-04	170	30	3	8ab67e2b6e30fdf9e9a2c02e31d4df34e751a3ed
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HHIPL1 CDK1 KLHL23	2.10e-04	173	30	3	20889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell	368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HHIPL1 CDK1 KLHL23	2.10e-04	173	30	3	46e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RARB PRSS12 GPX3	2.14e-04	174	30	3	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RARB PRSS12 GPX3	2.14e-04	174	30	3	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NDST3 TSSK4 GPX3	2.17e-04	175	30	3	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RARB PRSS12 GPX3	2.21e-04	176	30	3	40993c41c1017b53039a337174fc56632b278609
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARB F2 RSPH1	2.29e-04	178	30	3	f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TSSK4 ADAM23 PRSS12	2.29e-04	178	30	3	3e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RARB PRSS12 GPX3	2.29e-04	178	30	3	0e1bedf991189d0ef9b40dac9281bdf4739333a1
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RARB F2 RSPH1	2.29e-04	178	30	3	6178706db4a855d72abc156537604d575624df56
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	RARB PRSS12 GPX3	2.32e-04	179	30	3	8766a5a066091879f521acfc612abf563ff78808
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF479 HHIPL1 RARB	2.36e-04	180	30	3	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF479 HHIPL1 RARB	2.36e-04	180	30	3	280ff5c8f292be1b88120db5ff1788b750644856
ToppCell	normal_Lung-Fibroblasts-Pericytes\|normal_Lung / Location, Cell class and cell subclass	LAMB1 KLHL23 GPX3	2.40e-04	181	30	3	f74941e49950027360d71ea3b205fc20c6929766
ToppCell	10x5'-bone_marrow-Lymphocytic_B-Pre-B\|bone_marrow / Manually curated celltypes from each tissue	KLHL14 ADAM23 SMAD1	2.44e-04	182	30	3	a5fd392178c2f533e265d2e3ce63b90c2553e4c1
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDK1 RARB PRSS12	2.44e-04	182	30	3	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	B_cell_maturation-immature_B_cell\|World / Lineage and Cell class	KLHL14 ADAM23 SMAD1	2.44e-04	182	30	3	2c7c51ebc4125d8a33454ffee0b143579ce5e451
ToppCell	5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NDST3 KLHL14 SMAD1	2.44e-04	182	30	3	53c267ee327e116dbd89d5927ed3bdf78d25ee62
ToppCell	facs-Heart-RA\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK8 KCNC2 GPX3	2.44e-04	182	30	3	8292e8e8474c930ffb88cbab4f6ebdb6f58db645
ToppCell	COPD-Stromal-Pericyte\|World / Disease state, Lineage and Cell class	LAMB1 KLHL23 GPX3	2.60e-04	186	30	3	8adfd2d1fda4e8aecc95192ea627bf7ed5214b8d
ToppCell	P15-Mesenchymal-developing_mesenchymal_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 KLHL23 GPX3	2.60e-04	186	30	3	db9b67066fc003c7995ec205d15176bf40c97add
ToppCell	356C-Endothelial_cells-Endothelial-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	SMAD1 HHIPL2 GPX3	2.60e-04	186	30	3	2e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell	356C-Endothelial_cells-Endothelial-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	SMAD1 HHIPL2 GPX3	2.60e-04	186	30	3	c3449e54454009973818fc1101933c6f0168258c
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB1 SCUBE1 GPX3	2.60e-04	186	30	3	d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LAMB1 KLHL23 GPX3	2.64e-04	187	30	3	fa01a61bfd13feb033ba1e35cf513707b1bff8c8
ToppCell	B_cell_maturation-immature_B_cell\|B_cell_maturation / Lineage and Cell class	KLHL14 ADAM23 SMAD1	2.64e-04	187	30	3	9afbb21654c8eb6f9c6a7cbd0664d890282ddceb
ToppCell	droplet-Spleen-nan-3m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CDK1 KLHL23 PM20D2	2.68e-04	188	30	3	1a3f95b4fd7611c634666761ddf21f1e58e56af8
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB1 SCUBE1 LANCL2	2.68e-04	188	30	3	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 PRSS12 GPX3	2.68e-04	188	30	3	7191087d8754f5e8700e3d744cd920ee26db1e57
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 KLHL23 GPX3	2.68e-04	188	30	3	e7681efb4d2de7f1d8a89552fff76a829376bf1b
ToppCell	facs-BAT-Fat-18m-Mesenchymal\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 ADAM23 GPX3	2.72e-04	189	30	3	bba28f57a0708515fdd5acd9592dbbe4a4f57116
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell-mesenchymal_myogenic_precursor_(Axin2+)\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 KLHL23 GPX3	2.72e-04	189	30	3	26cfe5b7e7f477f225f4e9f25f983f432f01e183
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_progenitor\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 ADAM23 GPX3	2.72e-04	189	30	3	cf293b23a4c0e8a0c9f09115b1d53d9b11de72e2
ToppCell	facs-BAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 ADAM23 GPX3	2.72e-04	189	30	3	87323e86a5b5d159920a07e6bd7ef5e3438cd085
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NDST3 ADAM23 PRSS12	2.72e-04	189	30	3	620d30bb6211fff6adab0638d0d994f547167a29
ToppCell	E17.5-Mesenchymal-developing_mesenchymal_cell\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 KLHL23 GPX3	2.77e-04	190	30	3	2ab604d35456beba71c25511e0f819000e6642d2
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABL1 RARB SMAD1	2.77e-04	190	30	3	a22a510b4a257eb0eaf09c7ae7978d3d2f07a58c
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABL1 RARB SMAD1	2.77e-04	190	30	3	57c136bf6d7feafb4a220877bed0cc8fdf314db2
ToppCell	droplet-Lung-21m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ABL1 RARB SMAD1	2.77e-04	190	30	3	f50b9814a1beac67dc042a8c27dfd085ceeda3a6
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMB1 RARB GPX3	2.77e-04	190	30	3	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LAMB1 CDK1 KLHL23	2.81e-04	191	30	3	ddbc5f97f2aef19be4ad93db4139876c939b848e
ToppCell	wk_15-18-Hematologic_Lymphocytic-B-pre-B-I_cell\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	KLHL14 ADAM23 SMAD1	2.81e-04	191	30	3	146edd214aac49f9b910bb982e3d77a052c8b316
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMB1 RARB GPX3	2.85e-04	192	30	3	df1545670370fb1010c567cd059c2783eab315f7
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LAMB1 PRSS12 GPX3	2.85e-04	192	30	3	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	NDST3 SCUBE1 KLHL23	2.90e-04	193	30	3	000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 ADAM23 SMAD1	2.94e-04	194	30	3	2e5b195e02dcd5e9432b9a98b22e0478e65b9ba2
ToppCell	facs-SCAT-Fat-3m-Mesenchymal\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 ADAM23 GPX3	2.94e-04	194	30	3	14b614f039bc866a1348a2728a68b7d254c7748c
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 ADAM23 GPX3	2.94e-04	194	30	3	68c7bfead1158641928cc276f599b4a79e06c73c
ToppCell	facs-SCAT-Fat-3m-Mesenchymal-mesenchymal_progenitor\|SCAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMB1 ADAM23 GPX3	2.94e-04	194	30	3	f6aeae6a1e4017e341323fd4784c9e3bae00552b
ToppCell	356C-Endothelial_cells-Endothelial-A_(Artery)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 ADAM23 SMAD1	2.94e-04	194	30	3	b6b5b0ab506b05a005ba8a05a3c7f4c725ba9200
ToppCell	Sepsis-Int-URO-Lymphocyte-B-Plasmablast\|Int-URO / Disease, condition lineage and cell class	CDK1 KLHL14 GPX3	3.03e-04	196	30	3	e65b47d0ce1a5dd05f5f50e1639c8ec76fb42dc8
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 RARB GPX3	3.03e-04	196	30	3	6730743cf088c419ccc2d28765769fc09d3ba6a7
ToppCell	cellseq-Mesenchymal-Myocytic-Myocytic_1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMB1 KLHL23 GPX3	3.03e-04	196	30	3	c373465e34e2dd581247962d59e0477aae877079
ToppCell	10x5'v1-week_12-13-Lymphocytic_B-B_lineage-pre_B_progenitor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	CDK1 KLHL14 SMAD1	3.03e-04	196	30	3	6ba02b806d440eed45bad7616bf3b8be57034427
ToppCell	367C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	LAMB1 RARB GPX3	3.03e-04	196	30	3	21dab89f3699037138a9c7a0e4dc98739a9fad9c
ToppCell	cellseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMB1 KLHL23 GPX3	3.03e-04	196	30	3	8b5337ccf74de90e8b89a02ac00671af1de2cfff
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMB1 KLHL23 GPX3	3.08e-04	197	30	3	41dd312f46a2b983c8d864adeb6970c0ca4a8048
ToppCell	Parenchymal-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMB1 KLHL23 GPX3	3.08e-04	197	30	3	f66945f9007d59d4208849c7fd727f8519713fbc
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB1 LANCL2 GPX3	3.08e-04	197	30	3	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB1 SCUBE1 GPX3	3.08e-04	197	30	3	69fde2d27881f8408216e231c71cfdbd96f28d45
ToppCell	Transverse-T_cell-cycling_gd_T\|Transverse / Region, Cell class and subclass	SCUBE1 CDK1 KLHL23	3.12e-04	198	30	3	5131b0b7d6c4dd8872cef9f2e233f59f751b4690
ToppCell	Transverse-(1)_T_cell-(18)_cycling_gd_T\|Transverse / shred on region, Cell_type, and subtype	SCUBE1 CDK1 KLHL23	3.12e-04	198	30	3	396dddf7ebad41c3a91329b6a280623c0dfdcd2f
ToppCell	ILEUM-inflamed-(8)_Fibroblasts\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LAMB1 KLHL23 GPX3	3.17e-04	199	30	3	3a3e2bb21cd0293622b1a975263e918d9ba24265
ToppCell	cellseq-Mesenchymal-Myocytic\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMB1 KLHL23 GPX3	3.17e-04	199	30	3	20e62a7029fa0d214244cdf2a481fc5d78290438
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB1 SCUBE1 GPX3	3.17e-04	199	30	3	ec74ff85d6b61013b1f785b2fca343759feb7843
ToppCell	Bronchial-NucSeq-Stromal-Pericyte-Muscle_pericyte_pulmonary\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	LAMB1 KLHL23 GPX3	3.17e-04	199	30	3	929f809579368201331d9099d8904b6e3c41797b
ToppCell	distal-mesenchymal-Pericyte-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LAMB1 KLHL23 GPX3	3.17e-04	199	30	3	e72ac7a00405cde06293d7adac7dc40eb0cf87ba
ToppCell	ILEUM-non-inflamed-(8)_Fibroblasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LAMB1 KLHL23 GPX3	3.17e-04	199	30	3	d9d7f36b4b5592b7855448730044c90997b55499
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Smooth_Muscle_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	LAMB1 KLHL23 GPX3	3.17e-04	199	30	3	31c781a1787e5140fb3f611823cbab4d13d02dfa
ToppCell	ILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts\|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LAMB1 KLHL23 GPX3	3.17e-04	199	30	3	615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell	ILEUM-non-inflamed-(8)_Fibroblast\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	LAMB1 KLHL23 GPX3	3.17e-04	199	30	3	6a0df9a2f30480043f9c1d7fbdede17eb0910cac
ToppCell	medial-mesenchymal-Pericyte-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LAMB1 KLHL23 GPX3	3.22e-04	200	30	3	bbda454260016be92b539e220ecf7bcbbc6139e4
ToppCell	medial-2-mesenchymal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LAMB1 KLHL23 GPX3	3.22e-04	200	30	3	a9d8aa5bcf383d98a9e2eaf4b1f8466982d6b088
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-FILIP1L\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RARB PRSS12 GPX3	3.22e-04	200	30	3	f6af5ef02625aaae21e885e1ebd195e34731e53a
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RARB PRSS12 GPX3	3.22e-04	200	30	3	f75d95376a340d467c4392b872b2a2dbdd184556
ToppCell	cellseq-Mesenchymal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	LAMB1 KLHL23 GPX3	3.22e-04	200	30	3	238285fc372ce2e5e4341fc3084a3a833bf4a0a6
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1--L3-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	RARB PRSS12 GPX3	3.22e-04	200	30	3	47791c93d03ee17c1ce17e27f075be4fc6f2590e
ToppCell	distal-3-mesenchymal-Pericyte\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LAMB1 KLHL23 GPX3	3.22e-04	200	30	3	911db29f254bb697610e720ba78816e2c7f57933
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Smooth_muscle-1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LAMB1 KLHL23 GPX3	3.22e-04	200	30	3	43b76e382b38b9856c07557a75e5b1ce0cee1d9e
Drug	Ro 8-8717	RARA RARB	1.68e-06	2	30	2	CID006438148
Drug	Tamibarotene	RARA RARB	1.68e-06	2	30	2	DB04942
Drug	AGN 193109	RARA RARB SMAD5	9.05e-06	31	30	3	CID000177238
Drug	SRI 5898-21	RARA RARB	1.01e-05	4	30	2	CID006439757
Drug	Tazarotene	RARA RARB	1.01e-05	4	30	2	DB00799
Drug	Cd2366	RARA RARB	1.67e-05	5	30	2	CID006443796
Drug	Alitretinoin	RARA RARB	2.51e-05	6	30	2	DB00523
Drug	Adapalene	RARA RARB	2.51e-05	6	30	2	DB00210
Drug	Etretinate	RARA RARB	2.51e-05	6	30	2	DB00926
Drug	Acitretin	RARA RARB	3.51e-05	7	30	2	DB00459
Drug	5-methoxypsoralen	SMAD1 SMAD5	3.51e-05	7	30	2	ctd:C022909
Drug	HX 600	RARA RARB	4.68e-05	8	30	2	ctd:C104181
Drug	2-naphthoic acid	RARA RARB	4.68e-05	8	30	2	CID000007123
Drug	4-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)benzoic acid	RARA RARB	4.68e-05	8	30	2	ctd:C064545
Drug	Adapalene	RARA RARB	4.68e-05	8	30	2	ctd:D000068816
Drug	TTNN	RARA RARB	4.68e-05	8	30	2	CID000135754
Drug	LDN 193189	SMAD1 SMAD5	4.68e-05	8	30	2	ctd:C554430
Drug	4-((4-(4-ethylphenyl)-2,2-dimethyl-(2H)-thiochromen-6-yl)ethynyl)benzoic acid	RARA RARB	4.68e-05	8	30	2	ctd:C121616
Drug	retinyl methyl ether	RARA RARB	6.01e-05	9	30	2	CID006436634
Drug	tetraarsenic tetrasulfide	CDK1 RARA RARB	6.71e-05	60	30	3	ctd:C534735
Drug	HX 630	RARA RARB	7.50e-05	10	30	2	ctd:C422175
Drug	Flavopiridol	CDK8 CDK1	7.50e-05	10	30	2	DB03496
Drug	CEPC	RARA RARB	7.50e-05	10	30	2	CID000011483
Drug	UVI 3003	RARA RARB	9.16e-05	11	30	2	ctd:C525131
Drug	NSC105327	CDK8 CDK1 CDK19	1.06e-04	70	30	3	CID005318433
Drug	4-hydroxyretinoic acid	RARA RARB	1.10e-04	12	30	2	ctd:C019429
Drug	Puromycin Aminonucleoside	LAMB1 RARA SMAD1 GPX3	1.13e-04	192	30	4	ctd:D011692
Drug	Vinpocetine [42971-09-5]; Up 200; 11.4uM; MCF7; HT_HG-U133A	WDR25 ADAM23 SMAD5 NR2E1	1.22e-04	196	30	4	7213_UP
Drug	alpha-estradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A_EA	LAMB1 ZNF586 RARA SMAD5	1.25e-04	197	30	4	1048_UP
Drug	iloprost; Down 200; 1uM; MCF7; HG-U133A	RARA ADAM23 CDK19 SMAD5	1.25e-04	197	30	4	427_DN
Drug	Ro 13-6298	RARA RARB	1.30e-04	13	30	2	CID006437076
Drug	Cd2665	RARA RARB	1.30e-04	13	30	2	CID000216241
Drug	Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; MCF7; HT_HG-U133A	RARA ADAM23 SMAD1 SMAD5	1.32e-04	200	30	4	2224_UP
Drug	Phenytoin	CDK1 RARA RARB F2 PRSS12	1.36e-04	385	30	5	ctd:D010672
Drug	Griseofulvin	LAMB1 RARA RARB	1.41e-04	77	30	3	ctd:D006118
Drug	3-deazacytidine	CDK8 CDK1 ABL1 CDK19	1.48e-04	206	30	4	CID000001652
Drug	AC1L1DMQ	RARA RARB	1.51e-04	14	30	2	CID000002418
Drug	TAC 101	RARA RARB	1.99e-04	16	30	2	ctd:C112689
Drug	PD166326	CDK1 ABL1	1.99e-04	16	30	2	CID000447700
Drug	protoporphyrin IX dimethyl ester	RARA RARB	2.25e-04	17	30	2	CID000194637
Drug	U0126	CDK1 ABL1 F2 SMAD1 SMAD5	2.27e-04	430	30	5	CID000005637
Drug	bexarotene	CDK1 RARA RARB F2 SMAD5	2.44e-04	437	30	5	ctd:C095105
Drug	SR11237	RARA RARB	2.53e-04	18	30	2	CID000127019
Drug	HX600	RARA RARB	2.53e-04	18	30	2	CID000128016
Drug	3,4-didehydroretinoic acid	RARA RARB	2.53e-04	18	30	2	CID000447276
Drug	4-(1H-imidazol-1-yl)retinoic acid	RARA RARB	2.53e-04	18	30	2	ctd:C496751
Drug	STO 609	RARA F2	2.83e-04	19	30	2	ctd:C458525
Drug	Mitoxantrone	LAMB1 RARA RARB GPX3	2.97e-04	247	30	4	ctd:D008942
Drug	imperatorin	SMAD1 SMAD5	3.81e-04	22	30	2	ctd:C031534
Drug	adapalene	RARA RARB	3.81e-04	22	30	2	CID000060164
Drug	Ro 15-0778	RARA RARB	4.17e-04	23	30	2	CID006436116
Drug	AC1L32JQ	RARA RARB	4.17e-04	23	30	2	CID000133319
Drug	4-hydroxyretinoic acid	RARA RARB	4.94e-04	25	30	2	CID006438629
Drug	AN-22	ABL1 RARA	5.77e-04	27	30	2	CID000055769
Drug	AC1L2X6Z	RARA RARB	5.77e-04	27	30	2	CID000130325
Drug	olomoucine	CDK8 CDK1 CDK19	6.90e-04	132	30	3	CID000004592
Drug	Vincristine	CDK1 KLHL14 F2 SMAD1 CDK19 KLHL23 PM20D2	7.09e-04	1182	30	7	ctd:D014750
Drug	AGN 193109	RARA RARB	7.14e-04	30	30	2	ctd:C096920
Drug	Ro 41-5253	RARA RARB	7.14e-04	30	30	2	ctd:C084904
Drug	gentamicin sulfate	F2 NR2E1	7.62e-04	31	30	2	CID000072396
Drug	BAME	NDST3 F2	8.12e-04	32	30	2	CID000150869
Drug	rhodioloside	SMAD1 SMAD5	8.12e-04	32	30	2	ctd:C009172
Drug	CD367	RARA RARB	8.64e-04	33	30	2	CID000119342
Drug	Retinoids	CDK1 RARA	9.17e-04	34	30	2	ctd:D012176
Drug	methyl ethyl ketone	CDK8 CDK1 ABL1 F2 CDK19	9.36e-04	587	30	5	CID000006569
Drug	imidacloprid	SMAD1 SMAD5	9.72e-04	35	30	2	ctd:C082359
Drug	Pesticides	LAMB1 RARB SMAD5	9.99e-04	150	30	3	ctd:D010575
Drug	trans-retinol acetate	RARA RARB	1.03e-03	36	30	2	CID000005057
Drug	monocrotaline pyrrole	CDK1 SMAD1	1.03e-03	36	30	2	CID000104764
Drug	5-amidinobenzimidazole	ABL1 RARA NR2E1	1.08e-03	154	30	3	CID000001800
Drug	Ro 41-5253	RARA RARB	1.09e-03	37	30	2	CID005312120
Drug	Cytochalasin D	ABL1 SMAD1	1.21e-03	39	30	2	ctd:D015638
Drug	purvalanol	CDK8 CDK1	1.27e-03	40	30	2	CID000448991
Drug	tazarotene	RARA RARB	1.27e-03	40	30	2	CID000005381
Disease	developmental and epileptic encephalopathy 87 (implicated_via_orthology)	CDK8 CDK19	8.68e-07	2	28	2	DOID:0112221 (implicated_via_orthology)
Disease	Neuralgia-Neuritis, Sciatic Nerve	RARA RARB	5.20e-06	4	28	2	C0751924
Disease	Sciatic Nerve Palsy	RARA RARB	5.20e-06	4	28	2	C0751925
Disease	Lesion of Sciatic Nerve	RARA RARB	5.20e-06	4	28	2	C0154748
Disease	Sciatic Neuritis	RARA RARB	5.20e-06	4	28	2	C0242013
Disease	Sciatic Neuropathy	RARA RARB	5.20e-06	4	28	2	C0149940
Disease	Congenital ocular coloboma (disorder)	LAMB1 RARA	3.11e-05	9	28	2	C0009363
Disease	juvenile polyposis syndrome (implicated_via_orthology)	SMAD1 SMAD5	6.73e-05	13	28	2	DOID:0050787 (implicated_via_orthology)
Disease	esophagus adenocarcinoma (is_implicated_in)	ABL1 GPX3	1.80e-04	21	28	2	DOID:4914 (is_implicated_in)
Disease	Adenocarcinoma	ABL1 RARB GPX3	1.81e-04	116	28	3	C0001418
Disease	Carcinoma, Granular Cell	ABL1 RARB GPX3	1.81e-04	116	28	3	C0205644
Disease	Adenocarcinoma, Tubular	ABL1 RARB GPX3	1.81e-04	116	28	3	C0205645
Disease	Adenocarcinoma, Oxyphilic	ABL1 RARB GPX3	1.81e-04	116	28	3	C0205642
Disease	Carcinoma, Cribriform	ABL1 RARB GPX3	1.81e-04	116	28	3	C0205643
Disease	Adenocarcinoma, Basal Cell	ABL1 RARB GPX3	1.81e-04	116	28	3	C0205641
Disease	Endometrioma	LAMB1 RARB GPX3	4.72e-04	161	28	3	C0269102
Disease	Endometriosis	LAMB1 RARB GPX3	4.72e-04	161	28	3	C0014175
Disease	Schizophrenia	NDST3 RARA F2 SMAD5 NR2E1	1.32e-03	883	28	5	C0036341
Disease	Withdrawal Symptoms	SMAD1 SMAD5	1.39e-03	58	28	2	C0087169
Disease	Drug Withdrawal Symptoms	SMAD1 SMAD5	1.39e-03	58	28	2	C0086189
Disease	Substance Withdrawal Syndrome	SMAD1 SMAD5	1.39e-03	58	28	2	C0038587
Disease	hepatocellular carcinoma (is_marker_for)	CDK1 F2 GPX3	2.85e-03	301	28	3	DOID:684 (is_marker_for)
Disease	hormone measurement	ZNF716 KLHL23	2.88e-03	84	28	2	EFO_0004730
Disease	amino acid measurement	CDK8 NDST3 LAMB1 WDR25	3.65e-03	678	28	4	EFO_0005134

Protein segments in the cluster

Peptide	Gene	Start	Entry
KGGEHCYYHGSIRGV	ADAM23	191	O75077
EYEGCKVGRGTYGHV	CDK19	21	Q9BWU1
DCHGGISGTIYEYGA	GPX3	31	P22352
DKYCVEYGVGVIGFH	NDST3	151	O95803
SGYHYGVSACEGCKG	RARA	96	P10276
SGYHYGVSACEGCKG	RARB	96	P10826
GGKGSHEGRLEVYYR	PRSS12	391	P56730
GDYTCASDGGIRKGY	KCNC2	581	Q96PR1
VGKSVTGGYVYRGCE	HHIPL1	471	Q96JK4
RKGYGICHGTAGNGY	LANCL2	361	Q9NS86
GYYGDPIIGSGDHCR	LAMB1	901	P07942
GKIYISGGVHNGEYV	KLHL14	471	Q9P2G3
IGGHCGYRGSCTYDK	KLHL23	421	Q8NBE8
HKLGGGQYGEVYEGV	ABL1	246	P00519
AYGHAVGKSVTGGYV	HHIPL2	491	Q6UWX4
VGKSVTGGYVYRGCE	HHIPL2	496	Q6UWX4
EYEGCKVGRGTYGHV	CDK8	21	P49336
QHCGGELGDYTGYIE	SCUBE1	796	Q8IWY4
DRSSGKHYGVYACDG	NR2E1	21	Q9Y466
GDTYEGSYEFGKRHG	RSPH1	41	Q8WYR4
SGCTVEIKGGAHDYY	PM20D2	301	Q8IYS1
GKGVHLYYVGGEVYA	SMAD5	331	Q99717
GKGVHLYYVGGEVYA	SMAD1	331	Q15797
GEGTYGVVYKGRHKT	CDK1	11	P06493
YKDQGGHSGERPYEC	ZNF586	76	Q9NXT0
DEYGYEVGKAIGHGS	TSSK4	21	Q6SA08
EVGKAIGHGSYGSVY	TSSK4	26	Q6SA08
SVGECEVHKGGYNYV	ZNF716	131	A6NP11
SVGEYEVHKGGYSEV	ZNF479	131	Q96JC4
GEGCDRDGKYGFYTH	F2	591	P00734
RYEGHKVEGYSVGCE	WDR25	466	Q64LD2
YAGGEHYRCEEFGKV	ZNF195	321	O14628