Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	glucokinase activity	HK2 HKDC1 GCK	4.29e-07	5	71	3	GO:0004340
GeneOntologyMolecularFunction	hexokinase activity	HK2 HKDC1 GCK	4.29e-07	5	71	3	GO:0004396
GeneOntologyMolecularFunction	fructokinase activity	HK2 HKDC1 GCK	4.29e-07	5	71	3	GO:0008865
GeneOntologyMolecularFunction	cGMP-dependent protein kinase activity	PRKG1 PRKG2	1.25e-05	2	71	2	GO:0004692
GeneOntologyMolecularFunction	D-glucose binding	HK2 HKDC1 GCK	1.52e-05	14	71	3	GO:0005536
GeneOntologyMolecularFunction	carbohydrate kinase activity	HK2 HKDC1 GCK	5.47e-05	21	71	3	GO:0019200
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SCYL2 HK2 TRPM7 PANK4 OBSCN HKDC1 GCK PRKG1 PRKG2 TAF1L	1.95e-04	709	71	10	GO:0016773
GeneOntologyMolecularFunction	kinase activity	SCYL2 HK2 TRPM7 PANK4 OBSCN HKDC1 GCK PRKG1 PRKG2 TAF1L	3.54e-04	764	71	10	GO:0016301
GeneOntologyMolecularFunction	cyclic nucleotide-dependent protein kinase activity	PRKG1 PRKG2	4.42e-04	9	71	2	GO:0004690
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	MAN1A2 BPHL CHIT1 KLB	4.98e-04	103	71	4	GO:0004553
GeneOntologyMolecularFunction	ATPase-coupled transmembrane transporter activity	ABCB7 ABCB5 ATP1B1 ABCA9	6.16e-04	109	71	4	GO:0042626
GeneOntologyMolecularFunction	ABC-type transporter activity	ABCB7 ABCB5 ABCA9	7.06e-04	49	71	3	GO:0140359
GeneOntologyMolecularFunction	ATP hydrolysis activity	ABCB7 DYNC2H1 ABCB5 DNAH2 CHD2 IDE ABCA9	9.62e-04	441	71	7	GO:0016887
GeneOntologyMolecularFunction	cGMP binding	PRKG1 PRKG2	1.45e-03	16	71	2	GO:0030553
GeneOntologyMolecularFunction	ATP-dependent activity	ABCB7 DYNC2H1 ABCB5 DNAH2 CHD2 IDE ATP1B1 ABCA9	1.48e-03	614	71	8	GO:0140657
GeneOntologyMolecularFunction	transferase activity, transferring phosphorus-containing groups	SCYL2 HK2 TRPM7 PANK4 OBSCN HKDC1 GCK PRKG1 PRKG2 TAF1L	1.71e-03	938	71	10	GO:0016772
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	MAN1A2 BPHL CHIT1 KLB	1.73e-03	144	71	4	GO:0016798
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DYNC2H1 DNAH2	1.84e-03	18	71	2	GO:0008569
GeneOntologyMolecularFunction	histone H3K4 methyltransferase activity	SMYD1 SETBP1	2.27e-03	20	71	2	GO:0042800
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SLC12A2 SCN7A ATP1B1 SLC6A14	3.23e-03	171	71	4	GO:0015081
GeneOntologyMolecularFunction	primary active transmembrane transporter activity	ABCB7 ABCB5 ATP1B1 ABCA9	3.73e-03	178	71	4	GO:0015399
Domain	Hexokinase_C	HK2 HKDC1 GCK	5.70e-07	5	73	3	IPR022673
Domain	Hexokinase_N	HK2 HKDC1 GCK	5.70e-07	5	73	3	IPR022672
Domain	Hexokinase_1	HK2 HKDC1 GCK	5.70e-07	5	73	3	PF00349
Domain	Hexokinase_2	HK2 HKDC1 GCK	5.70e-07	5	73	3	PF03727
Domain	HEXOKINASE_2	HK2 HKDC1 GCK	5.70e-07	5	73	3	PS51748
Domain	Hexokinase_BS	HK2 HKDC1 GCK	5.70e-07	5	73	3	IPR019807
Domain	HEXOKINASE_1	HK2 HKDC1 GCK	5.70e-07	5	73	3	PS00378
Domain	Hexokinase	HK2 HKDC1 GCK	1.14e-06	6	73	3	IPR001312
Domain	cGMP_dep_kinase	PRKG1 PRKG2	1.51e-05	2	73	2	IPR002374
Domain	SCP2_sterol-bd_dom	SCP2D1 HSD17B4	1.50e-04	5	73	2	IPR003033
Domain	-	SCP2D1 HSD17B4	1.50e-04	5	73	2	3.30.1050.10
Domain	SCP2	SCP2D1 HSD17B4	1.50e-04	5	73	2	PF02036
Domain	AAA+_ATPase	ABCB7 DYNC2H1 ABCB5 DNAH2 ABCA9	2.50e-04	144	73	5	IPR003593
Domain	AAA	ABCB7 DYNC2H1 ABCB5 DNAH2 ABCA9	2.50e-04	144	73	5	SM00382
Domain	DHC_N1	DYNC2H1 DNAH2	4.16e-04	8	73	2	PF08385
Domain	Dynein_heavy_dom-1	DYNC2H1 DNAH2	4.16e-04	8	73	2	IPR013594
Domain	LisH	TBL1Y TBL1XR1	5.33e-04	9	73	2	PF08513
Domain	HotDog_dom	ACOT11 HSD17B4	6.64e-04	10	73	2	IPR029069
Domain	-	ACOT11 HSD17B4	6.64e-04	10	73	2	3.10.129.10
Domain	ABC_tran	ABCB7 ABCB5 ABCA9	8.73e-04	48	73	3	PF00005
Domain	ABC_TRANSPORTER_2	ABCB7 ABCB5 ABCA9	8.73e-04	48	73	3	PS50893
Domain	ABC_TRANSPORTER_1	ABCB7 ABCB5 ABCA9	9.28e-04	49	73	3	PS00211
Domain	ABC_transporter-like	ABCB7 ABCB5 ABCA9	9.84e-04	50	73	3	IPR003439
Domain	Dynein_heavy_chain_D4_dom	DYNC2H1 DNAH2	1.33e-03	14	73	2	IPR024317
Domain	Dynein_HC_stalk	DYNC2H1 DNAH2	1.33e-03	14	73	2	IPR024743
Domain	Dynein_heavy_dom-2	DYNC2H1 DNAH2	1.33e-03	14	73	2	IPR013602
Domain	DHC_N2	DYNC2H1 DNAH2	1.33e-03	14	73	2	PF08393
Domain	MT	DYNC2H1 DNAH2	1.33e-03	14	73	2	PF12777
Domain	AAA_8	DYNC2H1 DNAH2	1.33e-03	14	73	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DYNC2H1 DNAH2	1.33e-03	14	73	2	IPR011704
Domain	AAA_5	DYNC2H1 DNAH2	1.33e-03	14	73	2	PF07728
Domain	DHC_fam	DYNC2H1 DNAH2	1.53e-03	15	73	2	IPR026983
Domain	Dynein_heavy_dom	DYNC2H1 DNAH2	1.53e-03	15	73	2	IPR004273
Domain	Dynein_heavy	DYNC2H1 DNAH2	1.53e-03	15	73	2	PF03028
Domain	cNMP-bd_CS	PRKG1 PRKG2	1.75e-03	16	73	2	IPR018488
Domain	ABC_membrane	ABCB7 ABCB5	3.93e-03	24	73	2	PF00664
Domain	tRNA-bd_arm	E2F5 PRKG1	3.93e-03	24	73	2	IPR010978
Domain	-	ARHGAP23 PLEKHO2 OBSCN NUMB PLCE1 MSN	4.24e-03	391	73	6	2.30.29.30
Domain	ABC_TM1F	ABCB7 ABCB5	5.33e-03	28	73	2	PS50929
Domain	LisH	TBL1Y TBL1XR1	5.33e-03	28	73	2	SM00667
Domain	ABC1_TM_dom	ABCB7 ABCB5	5.33e-03	28	73	2	IPR011527
Domain	LisH	TBL1Y TBL1XR1	5.33e-03	28	73	2	IPR006594
Domain	LISH	TBL1Y TBL1XR1	5.33e-03	28	73	2	PS50896
Domain	PH_dom-like	ARHGAP23 PLEKHO2 OBSCN NUMB PLCE1 MSN	6.39e-03	426	73	6	IPR011993
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CACTIN ABCB7 KIDINS220 SLC12A2 TRPM7 DYNC2H1 LNPEP PANK4 MRPS34 NUMB RICTOR SENP2 LSS RTN4IP1 EBNA1BP2	3.82e-07	1487	73	15	33957083
Pubmed	Proteomics identifies the developmental regulation of HKDC1 in liver of pigs and mice.	HK2 HKDC1 GCK	1.05e-06	10	73	3	37545422
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SCYL2 ABCB7 MIS18BP1 HK2 SLC12A2 TRPM7 PANK4 MRPS34 SENP2 TSC2 RTN4IP1 IDE EBNA1BP2 HSD17B4	2.39e-06	1496	73	14	32877691
Pubmed	Interaction of cCMP with the cGK, cAK and MAPK Kinases in Murine Tissues.	PRKG1 PRKG2	4.35e-06	2	73	2	25978317
Pubmed	The kinase complex mTORC2 promotes the longevity of virus-specific memory CD4+ T cells by preventing ferroptosis.	GPX4 RICTOR	4.35e-06	2	73	2	34949833
Pubmed	Cloning and expression of a novel cyclic GMP-dependent protein kinase from mouse brain.	PRKG1 PRKG2	4.35e-06	2	73	2	8514791
Pubmed	Impaired relaxation of stomach smooth muscle in mice lacking cyclic GMP-dependent protein kinase I.	PRKG1 PRKG2	4.35e-06	2	73	2	10694248
Pubmed	Long-term potentiation in the hippocampal CA1 region of mice lacking cGMP-dependent kinases is normal and susceptible to inhibition of nitric oxide synthase.	PRKG1 PRKG2	4.35e-06	2	73	2	9870937
Pubmed	A hexokinase isoenzyme switch in human liver cancer cells promotes lipogenesis and enhances innate immunity.	HK2 GCK	4.35e-06	2	73	2	33594203
Pubmed	Type II, but not type I, cGMP-dependent protein kinase reverses bFGF-induced proliferation and migration of U251 human glioma cells.	PRKG1 PRKG2	4.35e-06	2	73	2	23404188
Pubmed	Expression of cGMP-dependent protein kinase, PKGIα, PKGIβ, and PKGII in malignant and benign breast tumors.	PRKG1 PRKG2	4.35e-06	2	73	2	22791569
Pubmed	Intestinal secretory defects and dwarfism in mice lacking cGMP-dependent protein kinase II.	PRKG1 PRKG2	4.35e-06	2	73	2	8953039
Pubmed	Cyclic GMP-dependent protein kinases: understanding in vivo functions by gene targeting.	PRKG1 PRKG2	4.35e-06	2	73	2	10454212
Pubmed	Role of cGMP-kinase II in the control of renin secretion and renin expression.	PRKG1 PRKG2	4.35e-06	2	73	2	9788971
Pubmed	Structural Basis of Analog Specificity in PKG I and II.	PRKG1 PRKG2	4.35e-06	2	73	2	28793191
Pubmed	PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.	TSC2 PRKG1	4.35e-06	2	73	2	30700906
Pubmed	LZTR1 is a regulator of RAS ubiquitination and signaling.	SLC12A2 LNPEP NUMB RICTOR MSN	7.38e-06	127	73	5	30442766
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KIDINS220 SETBP1 PANK4 OBSCN NUMB LSS CHD2 IGSF9B IDE FNBP1L TBL1XR1 ALG12 NXPH4	1.21e-05	1489	73	13	28611215
Pubmed	Tuberous sclerosis complex 2 gene product interacts with human SMAD proteins. A molecular link of two tumor suppressor pathways.	TSC2 SMAD2	1.30e-05	3	73	2	15066998
Pubmed	mTORC1 and mTORC2 selectively regulate CD8⁺ T cell differentiation.	RICTOR TSC2	1.30e-05	3	73	2	25893604
Pubmed	Regulation and role of myocyte cyclic GMP-dependent protein kinase-1.	PRKG1 PRKG2	1.30e-05	3	73	2	20498039
Pubmed	Phosphorylation and regulation of G-protein-activated phospholipase C-beta 3 by cGMP-dependent protein kinases.	PRKG1 PRKG2	1.30e-05	3	73	2	11278298
Pubmed	Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.	ABCB7 ABCB5 ABCA9	1.33e-05	22	73	3	8894702
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	KIDINS220 SLC12A2 TRPM7 PLEKHO2 NUMB RICTOR MSN	1.47e-05	377	73	7	38117590
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SCYL2 KIDINS220 SLC12A2 ARHGAP23 PLEKHO2 NUMB EBNA1BP2 FNBP1L	2.46e-05	565	73	8	25468996
Pubmed	ICln159 folds into a pleckstrin homology domain-like structure. Interaction with kinases and the splicing factor LSm4.	PRKG1 PRKG2	2.60e-05	4	73	2	15905169
Pubmed	cGMP-dependent protein kinase Iβ interacts with p44/WDR77 to regulate androgen receptor-driven gene expression.	PRKG1 PRKG2	2.60e-05	4	73	2	23755100
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	DYNC2H1 OBSCN	2.60e-05	4	73	2	26147384
Pubmed	IRAG mediates NO/cGMP-dependent inhibition of platelet aggregation and thrombus formation.	PRKG1 PRKG2	2.60e-05	4	73	2	16990611
Pubmed	Fluid flow and interlinked feedback loops establish left-right asymmetric decay of Cerl2 mRNA.	DAND5 SMAD2	4.33e-05	5	73	2	23271656
Pubmed	Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.	TBL1Y TBL1XR1	4.33e-05	5	73	2	21459324
Pubmed	Glucose metabolism gene polymorphisms and clinical outcome in pancreatic cancer.	HK2 GCK	4.33e-05	5	73	2	20845477
Pubmed	Expression profile and overexpression outcome indicate a role for βKlotho in skeletal muscle fibro/adipogenesis.	FGF1 KLB	4.33e-05	5	73	2	26881702
Pubmed	TSC1 controls macrophage polarization to prevent inflammatory disease.	RICTOR TSC2	4.33e-05	5	73	2	25175012
Pubmed	SENP2 regulates MMP13 expression in a bladder cancer cell line through SUMOylation of TBL1/TBLR1.	SENP2 TBL1XR1	4.33e-05	5	73	2	26369384
Pubmed	The kinase domains of obscurin interact with intercellular adhesion proteins.	OBSCN ATP1B1	4.33e-05	5	73	2	23392350
Pubmed	Hepatic mTORC2 activates glycolysis and lipogenesis through Akt, glucokinase, and SREBP1c.	RICTOR GCK	4.33e-05	5	73	2	22521878
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MAN1A2 KIDINS220 SLC12A2 TBL1Y LNPEP MRPS34 NUMB RICTOR CHD2 ATP1B1 TBL1XR1 TAF1L	6.24e-05	1497	73	12	31527615
Pubmed	Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.	TBL1Y TBL1XR1	6.48e-05	6	73	2	28348241
Pubmed	TSC1 controls IL-1β expression in macrophages via mTORC1-dependent C/EBPβ pathway.	RICTOR TSC2	6.48e-05	6	73	2	27593484
Pubmed	Actin binding of human LIM and SH3 protein is regulated by cGMP- and cAMP-dependent protein kinase phosphorylation on serine 146.	PRKG1 PRKG2	6.48e-05	6	73	2	12571245
Pubmed	E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression.	E2F5 SMAD2	9.06e-05	7	73	2	12150994
Pubmed	The TSC-mTOR pathway mediates translational activation of TOP mRNAs by insulin largely in a raptor- or rictor-independent manner.	RICTOR TSC2	9.06e-05	7	73	2	19047368
Pubmed	Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.	TBL1Y TBL1XR1	9.06e-05	7	73	2	27646874
Pubmed	Hepatic glycogen synthesis in the absence of glucokinase: the case of embryonic liver.	HK2 GCK	9.06e-05	7	73	2	18165236
Pubmed	The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.	TBL1Y TBL1XR1	9.06e-05	7	73	2	15695367
Pubmed	betaKlotho is required for fibroblast growth factor (FGF) 21 signaling through FGF receptor (FGFR) 1c and FGFR3c.	FGF1 KLB	1.21e-04	8	73	2	18187602
Pubmed	Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.	TBL1Y TBL1XR1	1.21e-04	8	73	2	23770565
Pubmed	Case-control genome-wide association study of attention-deficit/hyperactivity disorder.	HKDC1 PRKG1	1.21e-04	8	73	2	20732627
Pubmed	A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.	TBL1Y TBL1XR1	1.21e-04	8	73	2	16127449
Pubmed	Left-right asymmetry in the level of active Nodal protein produced in the node is translated into left-right asymmetry in the lateral plate of mouse embryos.	DAND5 SMAD2	1.21e-04	8	73	2	21419113
Pubmed	A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.	SCYL2 SLC12A2 PLEKHO2 SNX8 CNPY3 RICTOR TBL1XR1 ALG12	1.32e-04	719	73	8	35337019
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	ACAD8 HK2 BPHL GPX4 MRPS34 RTN4IP1 IDE HSD17B4 ABCA9	1.37e-04	926	73	9	20877624
Pubmed	The lacrimal gland transcriptome is an unusually rich source of rare and poorly characterized gene transcripts.	CNPY3 PRKG1 ATP1B1	1.43e-04	48	73	3	15851553
Pubmed	mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3beta inhibition.	HK2 TSC2	1.55e-04	9	73	2	19620286
Pubmed	Glutathione depletion associated with the HIV-1 TAT protein mediates the extracellular appearance of acidic fibroblast growth factor.	GPX4 FGF1	1.55e-04	9	73	2	9501919
Pubmed	Ski co-repressor complexes maintain the basal repressed state of the TGF-beta target gene, SMAD7, via HDAC3 and PRMT5.	TBL1XR1 SMAD2	1.93e-04	10	73	2	19032343
Pubmed	A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.	TBL1Y TBL1XR1	1.93e-04	10	73	2	14980219
Pubmed	Common genetic determinants of glucose homeostasis in healthy children: the European Youth Heart Study.	GCK IDE	1.93e-04	10	73	2	19741166
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ABCB5 DNAH2 HKDC1 CHD2 EBNA1BP2 FNBP1L STOX1 HSD17B4 SLC6A14 CAPN11 MSN	2.01e-04	1442	73	11	35575683
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	SCYL2 CACTIN ABCB7 ARHGAP23 OBSCN CNPY3 CHD2 E2F5 EBNA1BP2 MSN	2.20e-04	1215	73	10	15146197
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	MIS18BP1 KIDINS220 SLC12A2 NUMB SENP2	2.35e-04	263	73	5	34702444
Pubmed	Non-proteolytic ubiquitination of OTULIN regulates NF-κB signaling pathway.	HK2 TSC2	2.36e-04	11	73	2	31504727
Pubmed	Genome-wide association study identifies three new susceptibility loci for esophageal squamous-cell carcinoma in Chinese populations.	TBL1XR1 PLCE1	2.36e-04	11	73	2	21642993
Pubmed	Cluap1 localizes preferentially to the base and tip of cilia and is required for ciliogenesis in the mouse embryo.	DAND5 SMAD2	2.36e-04	11	73	2	23742838
Pubmed	Severe neurologic impairment in mice with targeted disruption of the electrogenic sodium bicarbonate cotransporter NBCe2 (Slc4a5 gene).	SLC12A2 ATP1B1	2.83e-04	12	73	2	21705333
Pubmed	A glycolytic shift in Schwann cells supports injured axons.	RICTOR TSC2	2.83e-04	12	73	2	32807950
Pubmed	Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease.	NUMB EBNA1BP2	2.83e-04	12	73	2	7596406
Pubmed	CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.	KIDINS220 HK2 DYNC2H1 PANK4 MRPS34 RICTOR TSC2	2.84e-04	606	73	7	36538041
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	CACTIN MIS18BP1 JADE3 GPX4 CHD2 EBNA1BP2 TBL1XR1	2.90e-04	608	73	7	36089195
Pubmed	The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.	DAND5 DYNC2H1	3.34e-04	13	73	2	17884984
Pubmed	Tsc1 Haploinsufficiency Leads to Pax2 Dysregulation in the Developing Murine Cerebellum.	RICTOR TSC2	3.34e-04	13	73	2	35645731
Pubmed	ULK1 inhibits the kinase activity of mTORC1 and cell proliferation.	RICTOR TSC2	3.34e-04	13	73	2	21795849
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	ACAD8 HK2 BPHL GPX4 MRPS34 RTN4IP1 IDE HSD17B4 ABCA9	3.39e-04	1047	73	9	18614015
Pubmed	Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.	DYNC2H1 DNAH2	3.89e-04	14	73	2	9373155
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	ABCB7 NUMB TBL1XR1 SMAD2 MSN	4.17e-04	298	73	5	30737378
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	SAMD9 HK2 ARHGAP23 RICTOR HSD17B4 PLCE1 MSN	4.32e-04	650	73	7	38777146
Pubmed	Embryonic Lethality Due to Arrested Cardiac Development in Psip1/Hdgfrp2 Double-Deficient Mice.	E2F5 SMAD2	4.48e-04	15	73	2	26367869
Pubmed	Characterization of size-fractionated cDNA libraries generated by the in vitro recombination-assisted method.	DYNC2H1 RICTOR	4.48e-04	15	73	2	12056414
Pubmed	Mouse homologues of Shisa antagonistic to Wnt and Fgf signalings.	DAND5 FGF1	4.48e-04	15	73	2	17481602
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	ACAD8 OBSCN HKDC1 LSS IDE	4.56e-04	304	73	5	32235678
Pubmed	Characterization of immunoisolated human gastric parietal cells tubulovesicles: identification of regulators of apical recycling.	SLC12A2 LSS ATP1B1	5.17e-04	74	73	3	17255364
Pubmed	Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria.	FGF1 GCK TAF1L	5.59e-04	76	73	3	22323595
Pubmed	Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.	DAND5 DYNC2H1	5.79e-04	17	73	2	22357932
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	HK2 OBSCN CHD2 SMAD2 PLCE1 MSN	6.26e-04	497	73	6	23414517
Pubmed	Epithelial hedgehog signals pattern the intestinal crypt-villus axis.	PRKG2 FABP2	6.51e-04	18	73	2	15590741
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	KIDINS220 SLC12A2 TRPM7 LNPEP TSC2 SMAD2	6.74e-04	504	73	6	34432599
Pubmed	Impact of ancestry and common genetic variants on QT interval in African Americans.	TRPM7 ATP1B1	7.26e-04	19	73	2	23166209
Pubmed	Fgf9 signaling regulates small intestinal elongation and mesenchymal development.	SMAD2 FABP2	8.06e-04	20	73	2	18653563
Pubmed	ER-export and ARFRP1/AP-1-dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication.	SCYL2 ABCB7 KIDINS220 SLC12A2 LNPEP NUMB HSD17B4 MSN	8.55e-04	952	73	8	38569033
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	HK2 DNAH2 SENP2 GCK TBL1XR1 TAF1L CAPN11	8.56e-04	730	73	7	34857952
Pubmed	A Large-scale genetic association study of esophageal adenocarcinoma risk.	CYP2C18 TSC2 HSD17B4 ATP1B1 SMAD2	8.72e-04	351	73	5	20453000
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	ABCB7 MAN1A2 ARHGAP23 LNPEP HKDC1 MRPS34 LSS CHD2 HSD17B4 MSN	8.80e-04	1451	73	10	30550785
Pubmed	Gli3 repressor controls cell fates and cell adhesion for proper establishment of neurogenic niche.	NUMB CNTF	8.89e-04	21	73	2	25127137
Pubmed	KAT7/HBO1/MYST2 Regulates CENP-A Chromatin Assembly by Antagonizing Suv39h1-Mediated Centromere Inactivation.	MIS18BP1 JADE3	8.89e-04	21	73	2	27270040
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	VWC2 OBSCN DNAH2 TSC2 CHD2 IGSF9B STOX1	8.98e-04	736	73	7	29676528
Pubmed	Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.	KIDINS220 TRPM7 PANK4 GPX4 IDE ATP1B1	9.00e-04	533	73	6	25544563
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ABCB7 MAN1A2 SLC12A2 LNPEP CNPY3 TSC2 ATP1B1 ALG12 SMAD2	9.05e-04	1201	73	9	35696571
Pubmed	Loss of the PlagL2 transcription factor affects lacteal uptake of chylomicrons.	SNX8 FABP2	9.77e-04	22	73	2	17983586
Pubmed	The receptor guanylyl cyclase Npr2 is essential for sensory axon bifurcation within the spinal cord.	PRKG1 PRKG2	1.07e-03	23	73	2	17954614
Interaction	GMIP interactions	ACAD8 PANK4 GCK EBNA1BP2	6.77e-06	34	73	4	int:GMIP
Interaction	RHOJ interactions	SCYL2 ABCB7 KIDINS220 SLC12A2 TRPM7 LNPEP NUMB RICTOR FNBP1L ATP1B1 SMAD2	1.63e-05	633	73	11	int:RHOJ
Interaction	FGFR4 interactions	SCYL2 KIDINS220 ABCB5 FGF1 NUMB FNBP1L HSD17B4 KLB MSN	4.00e-05	458	73	9	int:FGFR4
Interaction	NRAS interactions	KIDINS220 SLC12A2 TRPM7 LNPEP PRPH2 NUMB RICTOR IDE HSD17B4 PLCE1 MSN	4.06e-05	699	73	11	int:NRAS
Interaction	RHOB interactions	SCYL2 ABCB7 KIDINS220 SLC12A2 TRPM7 LNPEP PLEKHO2 NUMB RICTOR TSC2 ATP1B1 MSN	4.50e-05	840	73	12	int:RHOB
Interaction	DIRAS3 interactions	SCYL2 KIDINS220 SLC12A2 TRPM7 LNPEP NUMB RICTOR	4.54e-05	262	73	7	int:DIRAS3
Cytoband	11q25	ACAD8 IGSF9B	7.91e-04	26	73	2	11q25
Cytoband	Ensembl 112 genes in cytogenetic band chr11q25	ACAD8 IGSF9B	1.13e-03	31	73	2	chr11q25
Cytoband	18q21.1	SETBP1 SMAD2	1.69e-03	38	73	2	18q21.1
Cytoband	10q22.1	HKDC1 STOX1	2.47e-03	46	73	2	10q22.1
Cytoband	Ensembl 112 genes in cytogenetic band chr10q23	CYP2C18 IDE PLCE1	3.77e-03	195	73	3	chr10q23
GeneFamily	ATP binding cassette subfamily B	ABCB7 ABCB5	4.39e-04	11	52	2	806
Coexpression	PURBEY_TARGETS_OF_CTBP1_NOT_SATB1_UP	HK2 SNX8 MRPS34 PRPH2 SENP2 E2F5 EBNA1BP2	1.88e-05	296	73	7	M2366
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_42H_DN	BPHL SMYD1 NUMB IDE PRKG2 TBL1XR1	2.04e-05	200	73	6	M9632
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	SCYL2 ABCB7 MAN1A2 TRPM7 LNPEP PRKG1 IDE TBL1XR1	1.75e-05	330	73	8	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A2 TRPM7 DYNC2H1 ACOT11 SCN7A ATP1B1	5.66e-07	183	73	6	2f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCell	LV-07._Pericyte\|World / Chamber and Cluster_Paper	SLC12A2 SCN7A FGF1 PRKG1 FNBP1L PLCE1	5.66e-07	183	73	6	273db6a3b00a93ca852498471187b642b5368185
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A2 TRPM7 ACOT11 ATP1B1 ABCA9	9.64e-06	173	73	5	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue-3\|TCGA-Breast / Sample_Type by Project: Shred V9	SMYD1 ABCB5 ABCA9 CAPN11 KLB	9.92e-06	174	73	5	7f8f5fafae08676d2b90cab9802c3c9320f1370e
ToppCell	TCGA-Breast-Solid_Tissue_Normal\|TCGA-Breast / Sample_Type by Project: Shred V9	SMYD1 ABCB5 ABCA9 CAPN11 KLB	9.92e-06	174	73	5	e2f240d60bffbe8e6d60f0bb405b231bd3c96875
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue-Breast_normal_tissue\|TCGA-Breast / Sample_Type by Project: Shred V9	SMYD1 ABCB5 ABCA9 CAPN11 KLB	9.92e-06	174	73	5	0f3ec0d0d4344e10c9b48adc9174123f6402dc51
ToppCell	TCGA-Breast-Solid_Tissue_Normal-Breast_normal_tissue\|TCGA-Breast / Sample_Type by Project: Shred V9	SMYD1 ABCB5 ABCA9 CAPN11 KLB	9.92e-06	174	73	5	1aadbf2642b6d1320ceabd92e6ff59e11f16c315
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM7 DYNC2H1 SCN7A ATP1B1 ALG12	1.08e-05	177	73	5	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGF1 LSS TSC2 IGSF9B PLCE1	1.17e-05	180	73	5	a37cc885fe3f6cb9df69d43358064c83c18412e7
ToppCell	facs-Heart-RV-24m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGF1 LSS TSC2 IGSF9B PLCE1	1.17e-05	180	73	5	63a6d532b16b8b15c7c9102148d7297ee3afd641
ToppCell	COVID-19-Heart-Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SLC12A2 SCN7A FGF1 PRKG1 PLCE1	1.20e-05	181	73	5	33cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCell	RV\|World / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 SMYD1 OBSCN	1.20e-05	181	73	5	bbe1e6e59d8889bd37d6e8303116cbdcafca7236
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A2 TRPM7 DYNC2H1 SCN7A ATP1B1	1.23e-05	182	73	5	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A2 TRPM7 DYNC2H1 ACOT11 ATP1B1	1.27e-05	183	73	5	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	COVID-19-Heart-Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	SLC12A2 SETBP1 FGF1 PRKG1 PLCE1	1.30e-05	184	73	5	21790cdfa3b4036ad413fd44b94e31563116f25f
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP2C18 HKDC1 PRKG2 TMC5 FABP2	1.37e-05	186	73	5	bdd9d3a432aab46e733469b362f0064d35c1ac49
ToppCell	3'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP2C18 HKDC1 PRKG2 TMC5 FABP2	1.40e-05	187	73	5	9042bd0f57213a51503d9df2e4dce3209b7772d3
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 SMYD1 OBSCN	1.40e-05	187	73	5	78cdcf8bc141d3b155c3c8af908431fc419c4d08
ToppCell	LV-04._Ventricular_Cardiomyocyte_I\|World / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 SMYD1 OBSCN	1.44e-05	188	73	5	0758b474457efa36488e0195f7357100f4b6a090
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	SETBP1 SNX8 E2F5 NXPH4 PLCE1	1.44e-05	188	73	5	18d16e3f095a109b6a690f46fe7fcd5674c3636b
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 PRKG2 TMC5 ATP1B1 PLCE1	1.48e-05	189	73	5	de51fbd6fdb24fc4549393cf41a020005444b2aa
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 SMYD1 OBSCN	1.48e-05	189	73	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 SMYD1 OBSCN	1.48e-05	189	73	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 PRKG1 PRKG2 TMC5 ATP1B1	1.52e-05	190	73	5	1d8e169d2448a34180c415843bb49aa45ed540c5
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 SMYD1 OBSCN	1.52e-05	190	73	5	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	E17.5-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	GPX4 FGF1 ATP1B1 SLC6A14 MSN	1.52e-05	190	73	5	15f314517ed47b12d287a12a7d18cb383310e25a
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 OBSCN PRKG1	1.52e-05	190	73	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 OBSCN PRKG1	1.56e-05	191	73	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	JADE3 SETBP1 SNX8 E2F5 NXPH4	1.63e-05	193	73	5	b5e44fe60dc84dc050d4fa3ccec4e257e51dc636
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	JADE3 SETBP1 SNX8 E2F5 NXPH4	1.63e-05	193	73	5	e2cf2f4f142e1b4dda3ded28b5208eef3f301a43
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_intermediate\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	JADE3 SETBP1 SNX8 E2F5 NXPH4	1.68e-05	194	73	5	7f62bd52779e2779447b23bdd330be4b5b35910a
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	JADE3 SETBP1 E2F5 NXPH4 PLCE1	1.68e-05	194	73	5	2b61023a602d336ed0de174e9141046173db34e6
ToppCell	PBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	JADE3 SETBP1 E2F5 NXPH4 PLCE1	1.68e-05	194	73	5	f2486b19ac52a48d19f80b38a5536bee3dad745b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A2 TRPM7 DYNC2H1 ATP1B1 ABCA9	1.72e-05	195	73	5	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	mild_COVID-19-B_intermediate\|World / disease group, cell group and cell class (v2)	JADE3 SETBP1 E2F5 NXPH4 PLCE1	1.80e-05	197	73	5	e909b898b7458071f176b6c04356ea3540589153
ToppCell	5'-Adult-SmallIntestine-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP2C18 HKDC1 TMC5 ATP1B1 FABP2	1.85e-05	198	73	5	8d629492d2199de8e036c19e9dacceb9c9e721a0
ToppCell	5'-Adult-SmallIntestine-Epithelial-mature_enterocytic-Enterocyte\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP2C18 HKDC1 TMC5 ATP1B1 FABP2	1.85e-05	198	73	5	6e6af8fad09f8e48b3f2ce463d5773b6a69864d1
ToppCell	COVID-19-COVID-19_Mild-Lymphocyte-B-B_intermediate\|COVID-19_Mild / Disease, condition lineage and cell class	JADE3 SETBP1 E2F5 NXPH4 PLCE1	1.89e-05	199	73	5	1c6a08d01f6c1a2a4b6587d3a4522efbd03275e1
ToppCell	5'-Adult-SmallIntestine-Epithelial-mature_enterocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP2C18 HKDC1 TMC5 ATP1B1 FABP2	1.89e-05	199	73	5	01c2721bc82cd672e9477029b4a7ecc77e2f1b00
ToppCell	severe-B_intermediate\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	JADE3 SETBP1 SNX8 E2F5 NXPH4	1.94e-05	200	73	5	6d0ac3d00400dd5657ee266f7b885381bf790ce1
ToppCell	mild-B_intermediate\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	JADE3 SETBP1 E2F5 NXPH4 PLCE1	1.94e-05	200	73	5	8e3132a1fe3708f725c5c4077878fb87bbea3678
ToppCell	MS-CD4-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	ARHGAP23 PANK4 HKDC1 NXPH4	8.51e-05	141	73	4	df257dd4dcc45c1ace57340798e150a6e932531d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWC2 ABCB5 SCN7A FGF1	9.23e-05	144	73	4	0322fef818a963be00535d5f141f028d43de5c6a
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 PRKG1 ATP1B1 NXPH4	9.23e-05	144	73	4	121853910eeea1ea0642b3cc99f9200015480368
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Myl1\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWC2 SCN7A LINGO4 FGF1	9.48e-05	145	73	4	590ba937c741ae67460f303eca88b1cd3ac87f64
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWC2 SCN7A FGF1 PLCE1	1.05e-04	149	73	4	98ae408d2d0347865875ff8bbd89d359decea526
ToppCell	droplet-Liver-LIVER_HEP-30m-Epithelial-hepatocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BPHL SASH3 FGF1 FABP2	1.08e-04	150	73	4	42fd42a0be918a77aca4e0c91f068bdd5a5d9286
ToppCell	droplet-Liver-LIVER_HEP-30m-Epithelial-Hepatocyte_(Midlobular)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BPHL SASH3 FGF1 FABP2	1.08e-04	150	73	4	954ca50b36dadaab625ab011aedbf550de2e566f
ToppCell	droplet-Liver-LIVER_HEP-30m-Epithelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BPHL SASH3 FGF1 FABP2	1.08e-04	150	73	4	c2fcdd62ec85cbf9783a525cd7556e16a1e55cd8
ToppCell	TCGA-Thymus-Primary_Tumor-Thymoma-Type_AB-8\|TCGA-Thymus / Sample_Type by Project: Shred V9	SLC12A2 SCN7A PRPH2 PLCE1	1.11e-04	151	73	4	5906562efd36fbcb91f96e0a0d3a8fe999ba1e79
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lect1_Oxtr\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SCN7A FGF1 TMC5 PLCE1	1.23e-04	155	73	4	99e749f7075e2c64e9a0bf91009f95b6969197c8
ToppCell	3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	LINGO4 PRKG1 FNBP1L ATP1B1	1.29e-04	157	73	4	eb2520c237543ea4869d4386afc0457b111f6193
ToppCell	Children_(3_yrs)-Mesenchymal-chondrocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	VWC2 SCN7A PRKG1 ABCA9	1.29e-04	157	73	4	f147e24f2ece82e1c54750868954d09b3c461804
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal-Rectum_normal_tissue-Rectum_normal_tissue-9\|TCGA-Colorectal / Sample_Type by Project: Shred V9	DAND5 SMYD1 SCN7A ABCA9	1.35e-04	159	73	4	f376bf6cd0ed374211edac3c384f3a78f0caef2a
ToppCell	facs-Large_Intestine-Proximal\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX4 HKDC1 PRKG2 FABP2	1.67e-04	168	73	4	23e0e1592d7400012d289adb10c7598285bae2e9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 SCN7A FGF1 PLCE1	1.67e-04	168	73	4	fc80e4fecfc92458eb627013a983041d8ca025a9
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGAP23 SCN7A FGF1 PLCE1	1.67e-04	168	73	4	e96859dbf51cf8c4def8ee8db132f4d874fb4381
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-Tuft-related-Microfold_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SLC12A2 TMC5 ATP1B1 SLC6A14	1.71e-04	169	73	4	a54a8494c1feff29d77ab4737fcfabc84ace5c94
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Ptprt_Pkp2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	VWC2 LINGO4 FGF1 PLCE1	1.75e-04	170	73	4	14aa86a4f526ed6986afcb28c49225522055550c
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX4 HKDC1 PRKG2 FABP2	1.75e-04	170	73	4	75b0486620cab838d3feb1c3aa965b487a906618
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Lgr5+_undifferentiated_cell_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RTN4IP1 IGSF9B HSD17B4 SLC6A14	1.75e-04	170	73	4	833b4f44ea1fa673dfc6b43ce45a79fe68ae3b05
ToppCell	ICU-NoSEP-Lymphocyte-B-B_intermediate\|ICU-NoSEP / Disease, Lineage and Cell Type	VWC2 PRPH2 E2F5 NXPH4	1.79e-04	171	73	4	c6b8578577aef4fe79c1a8ca778a068052f2c9d4
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VWC2 ACOT11 OBSCN MSN	1.83e-04	172	73	4	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.4\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SLC12A2 TMC5 ATP1B1 SLC6A14	1.87e-04	173	73	4	176b956e71d98e8275d698b39437fc326e5fe449
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A2 TRPM7 ACOT11 ABCA9	1.87e-04	173	73	4	4bc6d93716f093b460c8b047199db8cab5fea720
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Enterocyte\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HKDC1 TMC5 SLC6A14 FABP2	1.91e-04	174	73	4	2fbdb62e269acf4447b171700a615e878dde7f9f
ToppCell	droplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HKDC1 TMC5 SLC6A14 FABP2	1.91e-04	174	73	4	7c52b5d8f1e65e5208c952be341fa155ed0e6e76
ToppCell	facs-Heart-RV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKG1 TMC5 NXPH4 PLCE1	1.95e-04	175	73	4	bfac175b79bb7d3d81074a2407c206a7647ee75d
ToppCell	Healthy_Control-Myeloid-Mast\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	VWC2 ACOT11 SCN7A OBSCN	1.95e-04	175	73	4	ca187074adcc9b8bd0fa270e2ede1564c8e6c6cf
ToppCell	Healthy_Control-Myeloid-Mast-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	VWC2 ACOT11 SCN7A OBSCN	1.95e-04	175	73	4	eadbbcdf2aef4cee268bc70a7a2c4175d898953b
ToppCell	facs-Heart-RV-24m-Mesenchymal-valve_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRKG1 TMC5 NXPH4 PLCE1	1.95e-04	175	73	4	c94fb35bbac95123201ca87ca835aecaefc0c490
ToppCell	facs-Large_Intestine-Proximal-18m-Epithelial\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX4 HKDC1 PRKG2 FABP2	2.00e-04	176	73	4	d1c4c78a6d4a4ad37912eade4b7d16ef84b9a706
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-enterocyte_of_epithelium_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HKDC1 PRKG2 SLC6A14 FABP2	2.00e-04	176	73	4	7622f5a8e7320cc7b593141854107ecaf4adff7f
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-nan\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IDE PRKG2 HSD17B4 FABP2	2.00e-04	176	73	4	1dd54bfaa58541de51e5a8328651d390833bd480
ToppCell	facs-Large_Intestine-Proximal-18m\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPX4 HKDC1 PRKG2 FABP2	2.00e-04	176	73	4	8c2f830124b3bd7c3a483aabe060a1d202c4a409
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCN7A OBSCN FGF1 ABCA9	2.04e-04	177	73	4	bd602db857f37869ef76d14c05ef522c509f08ee
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A2 TRPM7 ACOT11 ATP1B1	2.04e-04	177	73	4	dc846d0feb94d4c289553cc3ac9dac81d10409cb
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VWC2 SCN7A PRKG1 PLCE1	2.08e-04	178	73	4	6ad46b0720298bcb927fd53468bb4ea0c199ad35
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-ependymal_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SASH3 SCN7A HKDC1 CHIT1	2.08e-04	178	73	4	b1db59344c074c7c80169fc2c5cd5fc89f3fe463
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Ependyma\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SASH3 SCN7A HKDC1 CHIT1	2.08e-04	178	73	4	579cdc14f28b459e200ae2102e0bd4df8a2c0dcb
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGF1 PRKG1 PRKG2 PLCE1	2.13e-04	179	73	4	8da6863edc756540bb097cc7221c1408640d9bb4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VWC2 SCN7A PRKG1 PLCE1	2.13e-04	179	73	4	d1365d48d1b017a7917f4f63a82ac4720c3d87df
ToppCell	facs-Heart-LV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGF1 PRKG1 PRKG2 PLCE1	2.13e-04	179	73	4	f39c13c99a07d009cc677e363ffe089089c64916
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	SETBP1 FGF1 PRKG1 PLCE1	2.13e-04	179	73	4	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	TRPM7 DYNC2H1 SCN7A ATP1B1	2.13e-04	179	73	4	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	LV\|World / Chamber and Cluster_Paper	VWC2 TRPM7 ACOT11 SMYD1	2.17e-04	180	73	4	5ac6f485a58bb29462fec02dfbe8eb70864eafe3
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGF1 PRKG1 PRKG2 PLCE1	2.17e-04	180	73	4	0059e5acade6c895fd629767bea1c15f40b0d1b0
ToppCell	facs-Heart-RV-3m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FGF1 PRKG1 PRKG2 PLCE1	2.17e-04	180	73	4	dfb8412e1e06fa7349e66eea2ef27d9ea98b7893
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A2 TRPM7 ACOT11 ABCA9	2.22e-04	181	73	4	e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC12A2 PRKG1 TMC5 NXPH4	2.27e-04	182	73	4	c84f44391932080df31c8765e363c3dff64b2bd1
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	VWC2 SCN7A PRKG1 PLCE1	2.32e-04	183	73	4	121791ef84e7ce377ed6f5b7953af8865e04958e
ToppCell	COVID-19-Epithelial_cells-ECM-high_epithelial\|COVID-19 / group, cell type (main and fine annotations)	PRKG1 TMC5 ATP1B1 SLC6A14	2.32e-04	183	73	4	dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCell	droplet-Large_Intestine\|droplet / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMC5 ATP1B1 SLC6A14 FABP2	2.32e-04	183	73	4	9d7ffcb9804b9a52448ccb56c9370b317a4b52a5
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 ACOT11 PLEKHO2 PLCE1	2.32e-04	183	73	4	25c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related-ICC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWC2 SLC12A2 ACOT11 ATP1B1	2.32e-04	183	73	4	262387ee8d43b96e5f1a77c75124459a506a6172
ToppCell	Control-Epithelial_cells-Airway_mucous\|Control / group, cell type (main and fine annotations)	CYP2C18 HK2 SLC12A2 TMC5	2.32e-04	183	73	4	15d24a4fb1ffe6cbafbd54fcd7dde9ddcfbe03b2
ToppCell	3'-GW_trimst-2-SmallIntestine-Mesenchymal-stromal_related\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWC2 SLC12A2 ACOT11 ATP1B1	2.32e-04	183	73	4	c85a707acbcb582912e8ac080a36d05f91cfd7a2
ToppCell	3'-Adult-SmallIntestine-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP2C18 HKDC1 PRKG2 FABP2	2.36e-04	184	73	4	ed7a8e79e5723a5f5a03f542203d9e50bdef5f50
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 ACOT11 PLEKHO2 PLCE1	2.41e-04	185	73	4	dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HK2 ACOT11 PLEKHO2 PLCE1	2.41e-04	185	73	4	bea69058afa5aa927fe15c1f8d46460562ec4dd4
Drug	palmitoylcarnitine	ACAD8 HK2 ACOT11 GCK PRKG1 PRKG2	9.30e-07	102	73	6	CID000000461
Drug	benzyl thiocyanate	SLC12A2 PRPH2 GCK	3.73e-06	10	73	3	CID000018170
Drug	AC1L1AH5	ACAD8 HK2 ACOT11 GCK HSD17B4 ALG12 FABP2	5.83e-06	215	73	7	CID000000986
Drug	dicyclohexyl phthalate	MAN1A2 CYP2C18 HK2 SLC12A2 LNPEP GPX4 LSS PRKG1 HSD17B4 SMAD2 PLCE1 MSN	1.30e-05	836	73	12	ctd:C036042
Drug	glibenclamide	ABCB7 ABCB5 FGF1 GCK PRKG1 IDE PRKG2 ABCA9	3.03e-05	382	73	8	CID000003488
Drug	AC1L4A4H	LSS IDE HSD17B4	3.47e-05	20	73	3	CID000182011
Drug	trequinsin	ABCB5 FGF1 PRKG1 PRKG2	3.62e-05	58	73	4	CID000005537
Drug	Cephapirin sodium salt [24356-60-3]; Down 200; 9uM; HL60; HT_HG-U133A	SLC12A2 TBL1Y NUMB LSS TMC5 ATP1B1	4.21e-05	198	73	6	2730_DN
Drug	2,3-anhydro-D-allose	HK2 GCK	6.06e-05	4	73	2	CID000191595
Drug	lofenal	HK2 GCK	6.06e-05	4	73	2	CID000159256
Drug	N'-hydroxyformamidine	PRKG1 PRKG2	6.06e-05	4	73	2	CID000012227
Drug	N-bromoacetylglucosamine	HK2 GCK	6.06e-05	4	73	2	CID000152920
Drug	1,5-anhydroglucitol 6-phosphate	HK2 GCK	6.06e-05	4	73	2	CID003081444
Drug	1-deoxy-D-manno-heptulose	HK2 GCK	6.06e-05	4	73	2	CID000193198
Drug	Trimm	PRKG1 PRKG2	6.06e-05	4	73	2	CID000017804
Drug	AC1L5VHN	HK2 GCK	6.06e-05	4	73	2	CID000235938
Disease	hyperinsulinemic hypoglycemia (implicated_via_orthology)	HK2 HKDC1 GCK	1.33e-07	5	71	3	DOID:13317 (implicated_via_orthology)
Disease	maturity-onset diabetes of the young (implicated_via_orthology)	HK2 HKDC1 GCK	1.58e-06	10	71	3	DOID:0050524 (implicated_via_orthology)
Disease	hyperglycemia (implicated_via_orthology)	HK2 HKDC1 GCK	8.86e-06	17	71	3	DOID:4195 (implicated_via_orthology)
Disease	sensory system disease (implicated_via_orthology)	TBL1Y TBL1XR1	1.71e-05	3	71	2	DOID:0050155 (implicated_via_orthology)
Disease	West Syndrome	CNPY3 TSC2 HSD17B4	2.61e-05	24	71	3	C0037769
Disease	glucose metabolism disease (implicated_via_orthology)	HK2 HKDC1 GCK	4.19e-05	28	71	3	DOID:4194 (implicated_via_orthology)
Disease	leiomyoma (is_marker_for)	LNPEP FGF1 TSC2	4.19e-05	28	71	3	DOID:127 (is_marker_for)
Disease	Colorectal Carcinoma	TRPM7 ABCB5 SETBP1 PANK4 SNX8 GPX4 OBSCN ABCA9 SMAD2	4.64e-05	702	71	9	C0009402
Disease	obesity (is_implicated_in)	HK2 CNTF SLC6A14 FABP2	7.02e-05	91	71	4	DOID:9970 (is_implicated_in)
Disease	Symptomatic Infantile Spasms	TSC2 HSD17B4	8.51e-05	6	71	2	C0393699
Disease	Cryptogenic Infantile Spasms	TSC2 HSD17B4	8.51e-05	6	71	2	C0393698
Disease	Salaam Seizures	TSC2 HSD17B4	8.51e-05	6	71	2	C1527366
Disease	Nodding spasm	TSC2 HSD17B4	8.51e-05	6	71	2	C0546878
Disease	spasmus nutans	TSC2 HSD17B4	8.51e-05	6	71	2	C1527306
Disease	Jackknife Seizures	TSC2 HSD17B4	8.51e-05	6	71	2	C0553558
Disease	Hypsarrhythmia	TSC2 HSD17B4	8.51e-05	6	71	2	C0684276
Disease	sensorineural hearing loss (biomarker_via_orthology)	SLC12A2 ATP1B1	1.58e-04	8	71	2	DOID:10003 (biomarker_via_orthology)
Disease	hypertension (biomarker_via_orthology)	CYP2C18 HK2 SLC12A2 PRKG1 HSD17B4	2.22e-04	227	71	5	DOID:10763 (biomarker_via_orthology)
Disease	IGFBP-3 measurement	CACTIN PANK4 TSC2	3.03e-04	54	71	3	EFO_0004626
Disease	pulse pressure measurement	SLC12A2 TRPM7 DYNC2H1 PLEKHO2 PRPH2 CHD2 GCK ATP1B1 TBL1XR1 PLCE1 KLB	4.69e-04	1392	71	11	EFO_0005763
Disease	epilepsy (implicated_via_orthology)	SLC12A2 SCN7A PRKG1 ATP1B1	6.54e-04	163	71	4	DOID:1826 (implicated_via_orthology)
Disease	uric acid measurement	TRPM7 DYNC2H1 SETBP1 SENP2 CHD2 FNBP1L KLB	6.60e-04	610	71	7	EFO_0004761
Disease	theta wave measurement	CHIT1 TMC5	7.58e-04	17	71	2	EFO_0006873
Disease	Epilepsy, Cryptogenic	SLC12A2 TSC2 CHD2	1.03e-03	82	71	3	C0086237
Disease	Awakening Epilepsy	SLC12A2 TSC2 CHD2	1.03e-03	82	71	3	C0751111
Disease	Aura	SLC12A2 TSC2 CHD2	1.03e-03	82	71	3	C0236018
Disease	platelet reactivity measurement, response to clopidogrel	CYP2C18 PLCE1	1.40e-03	23	71	2	EFO_0004985, GO_1903493
Disease	Neurodevelopmental Disorders	SETBP1 CHD2 TBL1XR1	1.48e-03	93	71	3	C1535926
Disease	Impaired glucose tolerance	SLC12A2 GPX4	1.65e-03	25	71	2	C0271650
Disease	cataract (is_implicated_in)	PANK4 LSS	1.79e-03	26	71	2	DOID:83 (is_implicated_in)
Disease	migraine disorder, pulse pressure measurement	DYNC2H1 PLCE1	1.79e-03	26	71	2	EFO_0005763, MONDO_0005277
Disease	glucose tolerance test	HKDC1 GCK	1.93e-03	27	71	2	EFO_0004307
Disease	lumbar disc degeneration	DYNC2H1 STOX1	2.07e-03	28	71	2	EFO_0004994
Disease	type 2 diabetes mellitus (implicated_via_orthology)	LNPEP GCK IDE	2.10e-03	105	71	3	DOID:9352 (implicated_via_orthology)
Disease	coronary artery disease	TRPM7 DYNC2H1 LNPEP LINGO4 CHD2 PRKG1 ATP1B1 SMAD2 PLCE1	2.21e-03	1194	71	9	EFO_0001645
Disease	Epilepsy	SLC12A2 TSC2 CHD2	2.34e-03	109	71	3	C0014544

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKEFLGRTGGSWFKI	ATP1B1	21	P05026
GLSFGKKEKKVGWNS	ACAD8	226	Q9UKU7
CAGSSLFLKKKWGIG	ABCA9	696	Q8IUA7
TFSIGLAVGLVKGWK	ABCB5	191	Q2M3G0
GTWSLEGNKLIGKFK	FABP2	81	P12104
GWNGKLAGGHLSTLK	ACOT11	576	Q8WXI4
GSGKLGLLEFKILWK	CAPN11	626	Q9UMQ6
KKSWLYKAGSLLVIG	ALG12	336	Q9BV10
SIKAARAKKIFGWGD	NXPH4	96	O95158
KGILLNWTKGFKASG	GCK	161	P35557
KTLLAIGGWNFGTQK	CHIT1	91	Q13231
ALGSWKAFLGLQKAR	DAND5	56	Q8N907
AQWGSGKSFLLKKLE	KIDINS220	466	Q9ULH0
KSNGGIVWGNIKKKL	MIS18BP1	1066	Q6P0N0
AKKIGFGKKTWTFCG	PRKG1	506	Q13976
LLKWTKGFKASGCEG	HK2	616	P52789
QKFGFGGKKKGSKWN	EBNA1BP2	246	Q99848
HKKGGAVAIPSWGKF	LSS	181	P48449
VGAKTDKGWSFLLGK	LNPEP	866	Q9UIQ6
FSIKNKKGSELWLGV	MSN	206	P26038
KKLKASLWALGNIGS	RICTOR	921	Q6R327
GFAKKIGSGQKTWTF	PRKG2	596	Q13237
TFWGLGALLTKTKKF	PANK4	221	Q9NVE7
KWLLGKTVLQAGGNV	OBSCN	2411	Q5VST9
AGGGLETISNLKAKW	DYNC2H1	1001	Q8NCM8
KKSKNSIQWKGVGAG	E2F5	106	Q15329
AKTTVGKAKGKLWLF	FNBP1L	311	Q5T0N5
KDKTVLGSINWAFLG	CHD2	601	O14647
KGGNIGAKWTIDLKS	HSD17B4	656	P51659
GAKWTIDLKSGSGKV	HSD17B4	661	P51659
WSGKKGDTAALGGKK	CNPY3	211	Q9BT09
VGDGGLFEKKLWGLK	CNTF	146	P26441
KKSRGGLTFIGEWKN	MAN1A2	436	O60476
TGALQVEGSWKKDGK	KLB	91	Q86Z14
LLGTFIWNKALEKKG	CACTIN	206	Q8WUQ7
VNKGLGILFSNGKRW	CYP2C18	106	P33260
KSKGWVNTLVGGQKE	IDE	351	P14735
PKGKGILGNAIKWNF	GPX4	151	P36969
KKVSLLGWSDGGITA	BPHL	131	Q86WA6
GLKKLHWALKGASAF	DNAH2	711	Q9P225
LLVSQGRWKKGLTGT	PIWIL3	376	Q7Z3Z3
GTWLGLLNGKVGSFK	SASH3	211	O75995
KGGALKTTKTGTKWA	JADE3	261	Q92613
FGLIALWSKGKGRVK	LINGO4	551	Q6UY18
FGKTGKKAVKAVLWV	NUMB	76	P49757
HGKAWGILTFKGKTE	MRPS34	111	P82930
GVTVGSKALKHFWKG	RTN4IP1	321	Q8WWV3
LKSGGYQAVKRWTKG	SENP2	446	Q9HC62
WGSLKQALKGLSVEF	SNX8	281	Q9Y5X2
DKGTLIGWTKGFKAT	HKDC1	611	Q2TB90
AQSKWKGAGKFILKL	PLCE1	2221	Q9P212
FLGIGNKKAFWGTEK	SAMD9	941	Q5K651
KHKGTKPQGASLAGW	TAF1L	441	Q8IZX4
NWFVGLKKNGSCKRG	FGF1	121	P05230
GKGRGLKATKEFWAA	SMYD1	16	Q8NB12
GGNGLAWKIFNGTKK	SCYL2	41	Q6P3W7
AGKFKVSGKVLLSWK	SCP2D1	131	Q9UJQ7
ALKWNKKGNFILSAG	TBL1XR1	271	Q9BZK7
LKSITWQRLGKGNSG	ABCB7	61	O75027
SKLKQAWVSQGGGAK	VWC2	91	Q2TAL6
VTWLKEGTLLGASGK	IGSF9B	171	Q9UPX0
WKAFLESVKKLGKGN	PRPH2	316	P23942
VVKRLLGWKKSAGGS	SMAD2	11	Q15796
EKGKKFGFSLLWRSL	STOX1	306	Q6ZVD7
LTKKGKKAGSGLRQW	ARHGAP23	701	Q9P227
TAESKGVVKFGWIKG	SLC12A2	276	P55011
ALKWNKKGNYVLSAG	TBL1Y	281	Q9BQ87
SLGQISGASKKGKIW	SCN7A	906	Q01118
KAGWIKKSSGGLLGF	PLEKHO2	21	Q8TD55
WQKTLKIIGGKFGTS	TMC5	431	Q6UXY8
AWLIVGAALFKGIKS	SLC6A14	246	Q9UN76
AKAQGKKGSAGNTWS	SETBP1	261	Q9Y6X0
LGKGLIKAAVTTGAW	TRPM7	156	Q96QT4
LLAGGRTKTWLVGNK	TSC2	1051	P49815