Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN1A SCN2A SCN4A SCN8A SCN9A

1.07e-0726915GO:0005248
GeneOntologyMolecularFunctionalkali metal ion binding

IMPA1 SCN1A SCN2A SCN8A SCN9A

1.07e-0726915GO:0031420
GeneOntologyMolecularFunctionsodium channel activity

SCN1A SCN2A SCN4A SCN8A SCN9A CNGB1

1.30e-0752916GO:0005272
GeneOntologyMolecularFunctionsodium ion binding

SCN1A SCN2A SCN8A SCN9A

3.90e-0714914GO:0031402
GeneOntologyMolecularFunctionATP hydrolysis activity

DHX16 ATP8B3 HSP90B2P DNAH10 DHX38 ATP2C2 MLH1 KIF13A DNAH5 DNAH8 DDX3X ABCB4

7.56e-074419112GO:0016887
GeneOntologyMolecularFunctionATP-dependent activity

DHX16 ATP8B3 HSP90B2P DNAH10 ZGRF1 DHX38 ATP2C2 MLH1 KIF13A DNAH5 DNAH8 DDX3X ABCB4

4.11e-066149113GO:0140657
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC38A1 SCN1A SCN2A SCN4A SCN8A SCN9A CNGB1

1.32e-05171917GO:0015081
GeneOntologyMolecularFunctionATP-dependent diacylglycerol kinase activity

DGKA DGKG DGKD

1.47e-0511913GO:0004143
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAI1 MYL3 DNAH10 KIF13A DNAH5 DNAH8

1.66e-05118916GO:0003774
GeneOntologyMolecularFunctionmonoatomic cation channel activity

KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A GRIN2C CNGB1

2.67e-05343919GO:0005261
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DHX16 ATP8B3 HSP90B2P DNAH10 DHX38 ATP2C2 ENTPD5 MLH1 KIF13A DNAH5 DNAH8 DDX3X ABCB4

4.81e-057759113GO:0017111
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC38A1 KCNF1 SCN1A SCN2A SCN4A ATP2C2 SCN8A SCN9A GRIN2C CNGB1

5.08e-054659110GO:0046873
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH10 DNAH5 DNAH8

7.11e-0518913GO:0008569
GeneOntologyMolecularFunctionpyrophosphatase activity

DHX16 ATP8B3 HSP90B2P DNAH10 DHX38 ATP2C2 ENTPD5 MLH1 KIF13A DNAH5 DNAH8 DDX3X ABCB4

1.07e-048399113GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DHX16 ATP8B3 HSP90B2P DNAH10 DHX38 ATP2C2 ENTPD5 MLH1 KIF13A DNAH5 DNAH8 DDX3X ABCB4

1.09e-048409113GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DHX16 ATP8B3 HSP90B2P DNAH10 DHX38 ATP2C2 ENTPD5 MLH1 KIF13A DNAH5 DNAH8 DDX3X ABCB4

1.09e-048409113GO:0016818
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

SLC38A1 KCNF1 SCN1A SCN2A SCN4A CNGB3 ATP2C2 SCN8A SCN9A GRIN2C CNGB1

2.14e-046649111GO:0008324
GeneOntologyMolecularFunctionmonoatomic ion channel activity

KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A GRIN2C CNGB1

2.45e-04459919GO:0005216
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH10 DNAH5 DNAH8

2.76e-0428913GO:0051959
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH10 KIF13A DNAH5 DNAH8

2.94e-0470914GO:0003777
GeneOntologyMolecularFunctionintracellularly cGMP-activated cation channel activity

CNGB3 CNGB1

4.25e-047912GO:0005223
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

SLC38A1 KCNF1 SCN1A SCN2A SCN4A ATP2C2 SCN8A SCN9A GRIN2C CNGB1

5.67e-046279110GO:0022890
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH10 DNAH5 DNAH8

6.36e-0437913GO:0045505
GeneOntologyMolecularFunctionchannel activity

KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A GRIN2C CNGB1

6.50e-04525919GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A GRIN2C CNGB1

6.58e-04526919GO:0022803
GeneOntologyMolecularFunctiontransporter activity

SLC38A1 ATP8B3 IGF1R KCNF1 SCN1A SCN2A SCN4A CNGB3 ATP2C2 SCN8A SCN9A GRIN2C CNGB1 ABCB4 CFHR4

6.87e-0412899115GO:0005215
GeneOntologyMolecularFunctionlipid kinase activity

DGKA DGKG DGKD

8.61e-0441913GO:0001727
GeneOntologyMolecularFunctionintracellularly cAMP-activated cation channel activity

CNGB3 CNGB1

9.03e-0410912GO:0005222
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

SLC38A1 KCNF1 SCN1A SCN2A SCN4A CNGB3 ATP2C2 SCN8A SCN9A GRIN2C CNGB1

9.47e-047939111GO:0015075
GeneOntologyMolecularFunctioncomplement component C3b binding

CFHR4 CFHR3

1.32e-0312912GO:0001851
GeneOntologyMolecularFunctionintracellularly cyclic nucleotide-activated monoatomic cation channel activity

CNGB3 CNGB1

1.55e-0313912GO:0005221
GeneOntologyMolecularFunctioncyclic nucleotide-activated monoatomic ion channel activity

CNGB3 CNGB1

1.55e-0313912GO:0043855
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC38A1 KCNF1 SCN1A SCN2A SCN4A ATP2C2 SCN8A SCN9A GRIN2C CNGB1

2.35e-037589110GO:0015318
GeneOntologyMolecularFunctioncGMP binding

CNGB3 CNGB1

2.36e-0316912GO:0030553
GeneOntologyMolecularFunctionfloppase activity

ATP8B3 ABCB4

2.36e-0316912GO:0140328
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential

SCN1A SCN2A

2.67e-0317912GO:0099508
GeneOntologyMolecularFunctionlamin binding

SYNE1 DMD

3.34e-0319912GO:0005521
GeneOntologyMolecularFunctionhistone H3K4 methyltransferase activity

SETD1B ASH1L

3.70e-0320912GO:0042800
GeneOntologyMolecularFunctiongated channel activity

KCNF1 SCN1A SCN2A CNGB3 GRIN2C CNGB1

4.24e-03334916GO:0022836
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN1A SCN2A SCN4A SCN8A SCN9A

4.79e-0736905GO:0086010
GeneOntologyBiologicalProcesscardiac muscle cell action potential

SCN1A SCN2A SCN4A SCN8A SCN9A DMD

2.22e-0687906GO:0086001
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC38A1 SCN1A SCN2A SCN4A SCN8A SCN9A DMD CNGB1

3.57e-06208908GO:0035725
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

SCN1A SCN2A SCN4A SCN8A SCN9A

7.52e-0662905GO:0086002
GeneOntologyBiologicalProcessneuronal action potential

SCN1A SCN2A SCN4A SCN8A SCN9A

8.14e-0663905GO:0019228
GeneOntologyBiologicalProcesscardiac muscle contraction

MYL3 SCN1A SCN2A SCN4A SCN8A SCN9A DMD

8.55e-06167907GO:0060048
GeneOntologyBiologicalProcessprophase

TOPAZ1 MLH1 DDX3X

9.43e-0610903GO:0051324
GeneOntologyBiologicalProcessmeiotic prophase I

TOPAZ1 MLH1 DDX3X

9.43e-0610903GO:0007128
GeneOntologyBiologicalProcesslipid phosphorylation

DGKA DGKG DGKD

1.29e-0511903GO:0046834
GeneOntologyBiologicalProcessmembrane depolarization

SCN1A SCN2A SCN4A SCN8A SCN9A CNGB1

1.50e-05121906GO:0051899
GeneOntologyBiologicalProcessmeiosis I cell cycle phase

TOPAZ1 MLH1 DDX3X

1.72e-0512903GO:0098764
GeneOntologyBiologicalProcesssodium ion transport

SLC38A1 SCN1A SCN2A SCN4A SCN8A SCN9A DMD CNGB1

2.72e-05275908GO:0006814
GeneOntologyBiologicalProcessmeiotic cell cycle phase

TOPAZ1 MLH1 DDX3X

2.82e-0514903GO:0098762
GeneOntologyBiologicalProcessM phase

TOPAZ1 MLH1 DDX3X

2.82e-0514903GO:0000279
GeneOntologyBiologicalProcessaction potential

KCNF1 SCN1A SCN2A SCN4A SCN8A SCN9A DMD

2.84e-05201907GO:0001508
GeneOntologyBiologicalProcessregulation of membrane potential

KCNF1 SYNE1 SCN1A SCN2A SCN4A SCN8A SCN9A MTMR2 GRIN2C DMD CNGB1

3.15e-055599011GO:0042391
GeneOntologyBiologicalProcesscilium movement involved in cell motility

DNAI1 DNAH10 TTLL6 ASH1L ARMC2 DNAH5 DNAH8

3.75e-05210907GO:0060294
GeneOntologyBiologicalProcesscilium-dependent cell motility

DNAI1 DNAH10 TTLL6 ASH1L ARMC2 DNAH5 DNAH8

4.35e-05215907GO:0060285
GeneOntologyBiologicalProcesscilium or flagellum-dependent cell motility

DNAI1 DNAH10 TTLL6 ASH1L ARMC2 DNAH5 DNAH8

4.35e-05215907GO:0001539
GeneOntologyBiologicalProcessstriated muscle contraction

MYL3 SCN1A SCN2A SCN4A SCN8A SCN9A DMD

4.62e-05217907GO:0006941
GeneOntologyBiologicalProcesscardiac muscle cell contraction

SCN1A SCN2A SCN4A SCN8A SCN9A

5.43e-0593905GO:0086003
GeneOntologyBiologicalProcessneuromuscular process

OTOF SCN1A SCN4A GRIN2C DMD CAMTA1 CFHR4

5.81e-05225907GO:0050905
GeneOntologyBiologicalProcessdetermination of adult lifespan

SCN1A SCN2A DMD CFHR4

9.07e-0554904GO:0008340
GeneOntologyBiologicalProcesspachytene

TOPAZ1 DDX3X

1.12e-044902GO:0000239
GeneOntologyBiologicalProcessnerve development

SCN1A SCN2A SCN8A DMD CNGB1

1.16e-04109905GO:0021675
GeneOntologyBiologicalProcesstransmission of nerve impulse

SCN1A SCN2A SCN4A SCN8A SCN9A

1.31e-04112905GO:0019226
GeneOntologyBiologicalProcesscilium movement

DNAI1 DNAH10 TTLL6 ASH1L ARMC2 DNAH5 DNAH8

1.46e-04261907GO:0003341
GeneOntologyBiologicalProcessouter dynein arm assembly

DNAI1 DNAH5 DNAH8

1.52e-0424903GO:0036158
GeneOntologyBiologicalProcessnegative regulation of protein kinase C signaling

DGKG DGKD

1.87e-045902GO:0090038
GeneOntologyBiologicalProcesscell cycle phase

TOPAZ1 MLH1 DDX3X

2.18e-0427903GO:0022403
GeneOntologyBiologicalProcessactin-mediated cell contraction

SCN1A SCN2A SCN4A SCN8A SCN9A

2.37e-04127905GO:0070252
GeneOntologyBiologicalProcessdiacylglycerol metabolic process

DGKA DGKG DGKD

2.43e-0428903GO:0046339
GeneOntologyBiologicalProcessheart contraction

MYL3 SCN1A SCN2A SCN4A SCN8A SCN9A DMD

3.29e-04298907GO:0060047
GeneOntologyBiologicalProcessheart process

MYL3 SCN1A SCN2A SCN4A SCN8A SCN9A DMD

4.09e-04309907GO:0003015
GeneOntologyBiologicalProcessmicrotubule bundle formation

DNAI1 TTLL6 ARMC2 DNAH5 DNAH8

4.36e-04145905GO:0001578
GeneOntologyBiologicalProcessphosphatidic acid biosynthetic process

DGKA DGKG DGKD

5.17e-0436903GO:0006654
GeneOntologyBiologicalProcessolfactory nerve development

DMD CNGB1

5.18e-048902GO:0021553
GeneOntologyBiologicalProcessactin filament-based movement

SCN1A SCN2A SCN4A SCN8A SCN9A

5.57e-04153905GO:0030048
GeneOntologyBiologicalProcesssensory perception of mechanical stimulus

OTOF OTOGL SCN1A ROR1 SCN8A SCN9A

6.15e-04238906GO:0050954
GeneOntologyBiologicalProcessphosphatidic acid metabolic process

DGKA DGKG DGKD

7.60e-0441903GO:0046473
GeneOntologyBiologicalProcessaxonemal dynein complex assembly

DNAI1 DNAH5 DNAH8

7.60e-0441903GO:0070286
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

SLC38A1 KCNF1 SCN1A SCN2A SCN4A CNGB3 ATP2C2 SCN8A SCN9A GRIN2C DMD CNGB1

7.90e-049429012GO:0098655
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN1A SCN2A SCN4A SCN8A SCN9A

8.31e-0917915GO:0001518
GeneOntologyCellularComponentsodium channel complex

SCN1A SCN2A SCN4A SCN8A SCN9A

1.53e-0729915GO:0034706
GeneOntologyCellularComponentaxonemal dynein complex

DNAI1 DNAH10 DNAH5 DNAH8

3.96e-0625914GO:0005858
GeneOntologyCellularComponentmonoatomic ion channel complex

CYBB KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A GRIN2C CNGB1

5.81e-063789110GO:0034702
GeneOntologyCellularComponentcation channel complex

KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A CNGB1

8.63e-06235918GO:0034703
GeneOntologyCellularComponentouter dynein arm

DNAI1 DNAH5 DNAH8

1.71e-0512913GO:0036157
GeneOntologyCellularComponenttransporter complex

CYBB ATP8B3 KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A GRIN2C CNGB1

2.67e-055509111GO:1990351
GeneOntologyCellularComponentaxon

SLC38A1 IGF1R IMPA1 SCN1A SCN2A ROR1 SCN4A SCN8A SCN9A MTMR2 TSC2 DMD CNGB1 CFHR4

2.97e-058919114GO:0030424
GeneOntologyCellularComponentnode of Ranvier

SCN1A SCN2A SCN8A

8.62e-0520913GO:0033268
GeneOntologyCellularComponentdynein complex

DNAI1 DNAH10 DNAH5 DNAH8

9.00e-0554914GO:0030286
GeneOntologyCellularComponenttransmembrane transporter complex

CYBB KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A GRIN2C CNGB1

9.23e-055239110GO:1902495
GeneOntologyCellularComponentaxon initial segment

SCN1A SCN2A SCN8A

2.69e-0429913GO:0043194
GeneOntologyCellularComponentintracellular cyclic nucleotide activated cation channel complex

CNGB3 CNGB1

3.88e-047912GO:0017071
GeneOntologyCellularComponentmicrotubule associated complex

DNAI1 DNAH10 KIF13A DNAH5 DNAH8

6.95e-04161915GO:0005875
GeneOntologyCellularComponentsynaptic membrane

NRXN3 OTOF SYNE1 SCN1A SCN2A SCN8A MTMR2 GRIN2C DMD

9.87e-04583919GO:0097060
GeneOntologyCellularComponentplasma membrane protein complex

CYBB IGF1R KCNF1 SCN1A SCN2A SCN4A SCN8A SCN9A GRIN2C DMD

2.18e-037859110GO:0098797
HumanPhenoComplex febrile seizure

SCN1A SCN2A SCN8A SCN9A

4.50e-0616384HP:0011172
HumanPhenoPhotosensitive myoclonic seizure

SCN1A SCN2A SCN9A

2.09e-058383HP:0001327
HumanPhenoCyanotic episode

SCN1A SCN2A SCN9A

2.09e-058383HP:0200048
HumanPhenoFocal hemiclonic seizure

SCN1A SCN2A SCN8A SCN9A

2.98e-0525384HP:0006813
HumanPhenoCortical dysplasia

SCN1A SCN2A SCN9A TSC2 DDX3X

5.10e-0556385HP:0002539
HumanPhenoLimited neck range of motion

SCN1A SCN2A SCN9A

6.07e-0511383HP:0000466
HumanPhenoEpilepsia partialis continua

SCN1A SCN2A SCN9A

8.05e-0512383HP:0012847
HumanPhenoFocal automatism seizure

SCN1A SCN2A SCN8A

8.05e-0512383HP:0032898
HumanPhenoObsessive-compulsive trait

SCN1A SCN2A ASH1L SCN9A

9.23e-0533384HP:0008770
HumanPhenoGeneralized clonic seizure

SCN1A SCN2A SCN8A SCN9A

1.04e-0434384HP:0011169
HumanPhenoGeneralized cerebral atrophy/hypoplasia

SCN1A SCN2A SCN9A

1.04e-0413383HP:0007058
HumanPhenoFacial tics

SCN1A SCN2A SCN9A

1.64e-0415383HP:0011468
HumanPhenoPhotosensitive tonic-clonic seizure

SCN1A SCN2A SCN9A

1.64e-0415383HP:0007207
HumanPhenoDysgenesis of the hippocampus

SCN1A SCN2A SCN9A

2.01e-0416383HP:0025101
HumanPhenoFocal clonic seizure

SCN1A SCN2A SCN8A SCN9A

2.41e-0442384HP:0002266
HumanPhenoFocal motor status epilepticus

SCN1A SCN2A SCN9A

2.42e-0417383HP:0032663
HumanPhenoAtypical absence status epilepticus

SCN1A SCN2A SCN9A

2.42e-0417383HP:0011151
HumanPhenoVisually-induced seizure

SCN1A SCN2A SCN9A

2.89e-0418383HP:0020216
HumanPhenoGeneralized non-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

2.89e-0418383HP:0032860
HumanPhenoFocal impaired awareness seizure

CRELD1 SCN1A SCN2A SCN8A SCN9A TSC2

2.93e-04126386HP:0002384
HumanPhenoClonic seizure

CRELD1 SCN1A SCN2A SCN8A SCN9A

2.99e-0481385HP:0020221
HumanPhenoAtypical absence seizure

CRELD1 SCN1A SCN2A SCN9A

3.43e-0446384HP:0007270
HumanPhenoNon-convulsive status epilepticus without coma

SCN1A SCN2A SCN9A

4.00e-0420383HP:0032671
HumanPhenoAbnormal hippocampus morphology

SCN1A SCN2A SCN9A CAMTA1

4.05e-0448384HP:0025100
HumanPhenoAbnormal morphology of the limbic system

SCN1A SCN2A SCN9A CAMTA1

4.39e-0449384HP:0007343
HumanPhenoEEG with spike-wave complexes

SETD1B SCN1A SCN2A SCN8A SCN9A

4.40e-0488385HP:0010850
HumanPhenoTalipes valgus

SCN1A SCN2A SCN9A

4.64e-0421383HP:0004684
HumanPhenoNeonatal electro-clinical non-motor seizure

SCN2A SCN8A

5.34e-045382HP:0032812
HumanPhenoNeonatal seizure with electrographic correlate

SCN2A SCN8A

5.34e-045382HP:0032808
HumanPhenoNeonatal electro-clinical seizure

SCN2A SCN8A

5.34e-045382HP:0032809
HumanPhenoNeonatal electro-clinical seizure with behavior arrest

SCN2A SCN8A

5.34e-045382HP:0032823
HumanPhenoFocal head nodding automatism seizure

SCN2A SCN8A

5.34e-045382HP:0032906
HumanPhenoReflex seizure

SCN1A SCN2A SCN9A

5.35e-0422383HP:0020207
HumanPhenoBilateral tonic-clonic seizure with generalized onset

CRELD1 SCN1A SCN2A SCN9A

5.52e-0452384HP:0025190
HumanPhenoMyoclonic seizure

CRELD1 SETD1B SCN1A SCN2A SCN8A SCN9A RTN4IP1 CAMTA1

5.59e-04262388HP:0032794
HumanPhenoTibial torsion

SCN1A SCN2A SCN9A

6.12e-0423383HP:0100694
HumanPhenoEpileptic spasm

DHX16 CRELD1 SCN1A SCN2A SCN8A UGDH TSC2

7.12e-04207387HP:0011097
HumanPhenoPes valgus

SCN1A SCN2A SCN4A SCN9A

7.33e-0456384HP:0008081
HumanPhenoNormal interictal EEG

SCN2A SCN8A

7.98e-046382HP:0002372
MousePhenoincreased circulating LDL cholesterol level

CT45A6 CT45A1 CT45A3 CT45A10 CT45A2 CT45A7 CT45A9

2.68e-0780777MP:0000182
MousePhenoimpaired muscle relaxation

SCN4A SCN8A DMD CFHR4

1.58e-0528774MP:0003157
MousePhenoabnormal circulating LDL cholesterol level

CT45A6 CT45A1 CT45A3 CT45A10 CT45A2 CT45A7 CT45A9

3.12e-05163777MP:0000181
MousePhenoabnormal circulating non-HDL cholesterol level

CT45A6 CT45A1 CT45A3 CT45A10 CT45A2 CT45A7 CT45A9

5.88e-05180777MP:0020151
DomainINT_SG_DDX_CT_C

CT45A1 CT45A3 CT45A10 CT45A7 CT45A9

1.15e-108885PF15300
DomainINT_SG_DDX_CT_C

CT45A1 CT45A3 CT45A10 CT45A7 CT45A9

1.15e-108885IPR029307
DomainNa_channel_asu

SCN1A SCN2A SCN4A SCN8A SCN9A

5.12e-1010885IPR001696
DomainNa_trans_assoc

SCN1A SCN2A SCN4A SCN8A SCN9A

5.12e-1010885IPR010526
DomainNa_trans_assoc

SCN1A SCN2A SCN4A SCN8A SCN9A

5.12e-1010885PF06512
DomainNa_trans_cytopl

SCN1A SCN2A SCN8A SCN9A

6.85e-096884PF11933
DomainNa_trans_cytopl

SCN1A SCN2A SCN8A SCN9A

6.85e-096884IPR024583
DomainIon_trans_dom

KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A CNGB1

6.44e-08114888IPR005821
DomainIon_trans

KCNF1 SCN1A SCN2A SCN4A CNGB3 SCN8A SCN9A CNGB1

6.44e-08114888PF00520
DomainChannel_four-helix_dom

KCNF1 SCN1A SCN2A SCN4A SCN8A SCN9A

2.75e-0757886IPR027359
Domain-

KCNF1 SCN1A SCN2A SCN4A SCN8A SCN9A

2.75e-07578861.20.120.350
DomainIQ

SCN1A SCN2A SCN4A SCN8A SCN9A CAMTA1

2.25e-0681886SM00015
DomainIQ_motif_EF-hand-BS

SCN1A SCN2A SCN4A SCN8A SCN9A CAMTA1

4.17e-0690886IPR000048
DomainIQ

SCN1A SCN2A SCN4A SCN8A SCN9A CAMTA1

5.05e-0693886PS50096
DomainDHC_N1

DNAH10 DNAH5 DNAH8

5.56e-068883PF08385
DomainDynein_heavy_dom-1

DNAH10 DNAH5 DNAH8

5.56e-068883IPR013594
DomainEF-hand-dom_pair

MYL3 SCN1A SCN8A SCN9A DGKA DGKG LRRC74A DMD CBLB

8.33e-06287889IPR011992
DomainDAGK_acc

DGKA DGKG DGKD

1.18e-0510883PF00609
DomainDiacylglycerol_kin_accessory

DGKA DGKG DGKD

1.18e-0510883IPR000756
DomainDAGKa

DGKA DGKG DGKD

1.18e-0510883SM00045
DomainIQ

SCN1A SCN4A SCN8A SCN9A CAMTA1

2.11e-0571885PF00612
DomainDynein_heavy_chain_D4_dom

DNAH10 DNAH5 DNAH8

3.54e-0514883IPR024317
DomainDynein_HC_stalk

DNAH10 DNAH5 DNAH8

3.54e-0514883IPR024743
DomainDynein_heavy_dom-2

DNAH10 DNAH5 DNAH8

3.54e-0514883IPR013602
DomainDHC_N2

DNAH10 DNAH5 DNAH8

3.54e-0514883PF08393
DomainMT

DNAH10 DNAH5 DNAH8

3.54e-0514883PF12777
DomainAAA_8

DNAH10 DNAH5 DNAH8

3.54e-0514883PF12780
DomainATPase_dyneun-rel_AAA

DNAH10 DNAH5 DNAH8

3.54e-0514883IPR011704
DomainDAGKc

DGKA DGKG DGKD

3.54e-0514883SM00046
DomainAAA_5

DNAH10 DNAH5 DNAH8

3.54e-0514883PF07728
DomainDHC_fam

DNAH10 DNAH5 DNAH8

4.41e-0515883IPR026983
DomainDiacylglycerol_kinase_cat_dom

DGKA DGKG DGKD

4.41e-0515883IPR001206
DomainDAGK_cat

DGKA DGKG DGKD

4.41e-0515883PF00781
DomainDAGK

DGKA DGKG DGKD

4.41e-0515883PS50146
DomainDynein_heavy_dom

DNAH10 DNAH5 DNAH8

4.41e-0515883IPR004273
DomainDynein_heavy

DNAH10 DNAH5 DNAH8

4.41e-0515883PF03028
DomainRmlC_Cupin

CT45A1 CT45A3 CT45A2

5.41e-0516883IPR011051
DomainNAD/diacylglycerol_kinase

DGKA DGKG DGKD

6.55e-0517883IPR016064
DomainDAG_kinase_N

DGKA DGKG

6.56e-053882PF14513
DomainDAG_kinase_typeI_N

DGKA DGKG

6.56e-053882IPR029477
Domain-

DGKA DGKG

6.56e-0538821.10.238.110
Domain-

MYL3 DGKA DGKG LRRC74A DMD CBLB

1.46e-032618861.10.238.10
DomainC1_1

DGKA DGKG DGKD

2.46e-0357883PF00130
DomainPost-SET_dom

SETD1B ASH1L

2.52e-0316882IPR003616
DomainPostSET

SETD1B ASH1L

2.52e-0316882SM00508
DomaincNMP-bd_CS

CNGB3 CNGB1

2.52e-0316882IPR018488
DomainPOST_SET

SETD1B ASH1L

2.52e-0316882PS50868
DomainDUF1605

DHX16 DHX38

2.85e-0317882IPR011709
DomainOB_NTP_bind

DHX16 DHX38

2.85e-0317882PF07717
DomainHA2

DHX16 DHX38

3.20e-0318882SM00847
DomainHA2

DHX16 DHX38

3.20e-0318882PF04408
DomainFurin_repeat

CRELD1 IGF1R

3.20e-0318882IPR006212
DomainHelicase-assoc_dom

DHX16 DHX38

3.20e-0318882IPR007502
DomainHATPase_c

MORC1 MLH1

3.20e-0318882SM00387
DomainFU

CRELD1 IGF1R

3.20e-0318882SM00261
DomainZF_DAG_PE_1

DGKA DGKG DGKD

3.42e-0364883PS00479
DomainZF_DAG_PE_2

DGKA DGKG DGKD

3.42e-0364883PS50081
DomainHATPase_c

MORC1 MLH1

3.56e-0319882PF02518
DomainC1

DGKA DGKG DGKD

3.58e-0365883SM00109
DomainPE/DAG-bd

DGKA DGKG DGKD

3.73e-0366883IPR002219
Domain-

MORC1 MLH1

3.95e-03208823.30.565.10
DomainHATPase_C

MORC1 MLH1

4.35e-0321882IPR003594
PathwayREACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS

SCN1A SCN2A SCN4A SCN8A SCN9A

3.22e-0731675M877
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

SCN1A SCN2A SCN4A SCN8A SCN9A

3.80e-0732675M27455
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAI1 DNAH10 DNAH5 DNAH8

7.53e-0627674M47755
PathwayREACTOME_MUSCLE_CONTRACTION

MYL3 SCN1A SCN2A SCN4A SCN8A SCN9A DMD

4.85e-05203677M5485
PathwayKEGG_MEDICUS_REFERENCE_RETROGRADE_AXONAL_TRANSPORT

DNAI1 DNAH10 DNAH5 DNAH8

5.00e-0543674M47669
PathwayWP_ADHD_AND_AUTISM_ASD_PATHWAYS

NRXN3 SCN1A SCN2A SCN4A SCN8A SCN9A TSC2 ALDH1L1 GRIN2C

5.62e-05367679M48346
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_RETROGRADE_AXONAL_TRANSPORT

DNAI1 DNAH10 DNAH5 DNAH8

6.00e-0545674M47670
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

DGKA DGKG DGKD

2.19e-0425673MM14511
PathwayREACTOME_L1CAM_INTERACTIONS

SCN1A SCN2A SCN4A SCN8A SCN9A

2.71e-04121675M872
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

DGKA DGKG DGKD

2.77e-0427673M12123
PathwayWP_DRAVET_SYNDROME

SCN1A SCN2A SCN8A

3.09e-0428673M45519
PathwayKEGG_MEDICUS_REFERENCE_REGULATION_OF_COMPLEMENT_CASCADE_CFHR

CFHR4 CFHR3

3.30e-046672M47880
PathwayREACTOME_CARDIAC_CONDUCTION

SCN1A SCN2A SCN4A SCN8A SCN9A

3.77e-04130675M27454
PathwayKEGG_PHOSPHATIDYLINOSITOL_SIGNALING_SYSTEM

IMPA1 DGKA DGKG DGKD

4.62e-0476674M9052
Pubmed

Identification of cancer/testis-antigen genes by massively parallel signature sequencing.

CT45A8 CT45A6 CT45A1 CT45A3 CT45A10 CT45A5 CT45A2 CT45A7 CT45A9

2.32e-201593915905330
Pubmed

International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.

SCN1A SCN2A SCN4A SCN8A SCN9A

1.53e-11993516382098
Pubmed

A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.

SCN1A SCN2A SCN8A SCN9A

7.16e-10693423652591
Pubmed

Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.

SCN1A SCN2A SCN4A SCN8A

5.97e-09993415746173
Pubmed

Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.

SCN1A SCN2A SCN8A

1.85e-08393332845893
Pubmed

Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.

SCN1A SCN2A SCN8A

1.85e-08393328518218
Pubmed

Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.

SCN1A SCN2A SCN8A

1.85e-08393317928448
Pubmed

USP7 represses lineage differentiation genes in mouse embryonic stem cells by both catalytic and noncatalytic activities.

CYBB PLA2R1 CT45A6 CT45A1 TMEM132D CT45A3 CT45A10 SCN2A KCTD14 CT45A2 CT45A7 DDX3X CT45A9

3.04e-08674931337196079
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN1A SCN2A SCN8A SCN9A

3.36e-081393415123669
Pubmed

Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.

SCN1A SCN2A SCN8A

7.39e-08493317537961
Pubmed

Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.

SCN1A SCN2A SCN8A

7.39e-08493335031483
Pubmed

Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.

SCN1A SCN2A SCN8A

7.39e-08493329578003
Pubmed

Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.

SCN1A SCN2A SCN8A

7.39e-08493321156207
Pubmed

A new sodium channel alpha-subunit gene (Scn9a) from Schwann cells maps to the Scn1a, Scn2a, Scn3a cluster of mouse chromosome 2.

SCN1A SCN2A SCN9A

1.84e-0759338812438
Pubmed

Structure/function characterization of micro-conotoxin KIIIA, an analgesic, nearly irreversible blocker of mammalian neuronal sodium channels.

SCN2A SCN4A SCN8A

1.84e-07593317724025
Pubmed

Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.

SCN1A SCN2A SCN8A

6.43e-07793325818041
Pubmed

Interaction of muscle and brain sodium channels with multiple members of the syntrophin family of dystrophin-associated proteins.

SCN1A SCN4A DMD

1.03e-0689339412493
Pubmed

Diacylglycerol kinase delta regulates protein kinase C and epidermal growth factor receptor signaling.

DGKA DGKG DGKD

3.01e-061193317021016
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

OTOF SYNE1 ZGRF1 DMD KIF13A DNAH5 DDX3X

3.31e-0623493736243803
Pubmed

Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.

SCN1A SCN2A SCN8A

4.00e-061293330175250
Pubmed

Identification of dynein heavy chain genes expressed in human and mouse testis: chromosomal localization of an axonemal dynein gene.

DNAH10 DNAH5 DNAH8

6.60e-06149339373155
Pubmed

Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.

SCN1A SCN8A

7.07e-06293237901435
Pubmed

State- and use-dependent block of muscle Nav1.4 and neuronal Nav1.7 voltage-gated Na+ channel isoforms by ranolazine.

SCN4A SCN9A

7.07e-06293218079277
Pubmed

An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.

SCN1A SCN8A

7.07e-06293226410685
Pubmed

Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.

SCN1A SCN2A

7.07e-06293210827969
Pubmed

Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.

SCN1A SCN2A

7.07e-06293219694741
Pubmed

Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.

SCN2A SCN8A

7.07e-06293235348308
Pubmed

Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.

SCN2A SCN8A

7.07e-06293215760941
Pubmed

Differential expression of two sodium channel subtypes in human brain.

SCN1A SCN2A

7.07e-0629321317301
Pubmed

Voltage-gated sodium channel (SkM1) content in dystrophin-deficient muscle.

SCN4A DMD

7.07e-06293211316257
Pubmed

Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.

SCN1A SCN2A

7.07e-06293231439038
Pubmed

X-ROS signaling: rapid mechano-chemo transduction in heart.

CYBB DMD

7.07e-06293221903813
Pubmed

Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.

SCN1A SCN8A

7.07e-06293231943325
Pubmed

Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.

SCN1A SCN2A

7.07e-06293215249644
Pubmed

Sodium channel slow inactivation interferes with open channel block.

SCN8A SCN9A

7.07e-06293227174182
Pubmed

Reduced expression of Na(v)1.6 sodium channels and compensation by Na(v)1.2 channels in mice heterozygous for a null mutation in Scn8a.

SCN2A SCN8A

7.07e-06293218601978
Pubmed

FGF14 N-terminal splice variants differentially modulate Nav1.2 and Nav1.6-encoded sodium channels.

SCN2A SCN8A

7.07e-06293219465131
Pubmed

Congenital heart disease and other heterotaxic defects in a large cohort of patients with primary ciliary dyskinesia.

DNAI1 DNAH5

7.07e-06293217515466
Pubmed

SCN1A and SCN2A polymorphisms are associated with response to valproic acid in Chinese epilepsy patients.

SCN1A SCN2A

7.07e-06293230693367
Pubmed

Block of a subset of sodium channels exacerbates experimental autoimmune encephalomyelitis.

SCN2A SCN8A

7.07e-06293223735284
Pubmed

Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.

SCN1A SCN2A

7.07e-06293229649454
Pubmed

Primary ciliary dyskinesia: improving the diagnostic approach.

DNAI1 DNAH5

7.07e-06293219300264
Pubmed

IGF1R- and ROR1-Specific CAR T Cells as a Potential Therapy for High Risk Sarcomas.

IGF1R ROR1

7.07e-06293226173023
Pubmed

Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.

SCN1A SCN2A

7.07e-06293233096315
Pubmed

Sodium channel expression within chronic multiple sclerosis plaques.

SCN2A SCN8A

7.07e-06293217805013
Pubmed

Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.

SCN1A SCN2A

7.07e-06293226311622
Pubmed

Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.

SCN1A SCN8A

7.07e-06293233411788
Pubmed

The developmental changes of Na(v)1.1 and Na(v)1.2 expression in the human hippocampus and temporal lobe.

SCN1A SCN2A

7.07e-06293221377452
Pubmed

Persistent Nav1.1 and Nav1.6 currents drive spinal locomotor functions through nonlinear dynamics.

SCN1A SCN8A

7.07e-06293237665666
Pubmed

The voltage-gated sodium channel Scn8a is a genetic modifier of severe myoclonic epilepsy of infancy.

SCN1A SCN8A

7.07e-06293217881658
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNAH10 SYNE1 SCN1A DMD PARP14 DNAH8

1.15e-0518793626460568
Pubmed

Regulation of alternative splicing by SRrp86 and its interacting proteins.

DGKA DGKD SRSF9 DDX3X

1.70e-055793414559993
Pubmed

Voltage-gated sodium channels in taste bud cells.

SCN2A SCN9A

2.12e-05393219284629
Pubmed

Association of SCN1A, SCN2A, and UGT2B7 Polymorphisms with Responsiveness to Valproic Acid in the Treatment of Epilepsy.

SCN1A SCN2A

2.12e-05393232185219
Pubmed

Clinical exome sequencing as the first-tier test for diagnosing developmental disorders covering both CNV and SNV: a Chinese cohort.

SCN1A SCN2A

2.12e-05393232005694
Pubmed

Functional properties of complement factor H-related proteins FHR-3 and FHR-4: binding to the C3d region of C3b and differential regulation by heparin.

CFHR4 CFHR3

2.12e-05393210622723
Pubmed

Mutations in the sodium channel genes SCN1A, SCN3A, and SCN9A in children with epilepsy with febrile seizures plus(EFS+).

SCN1A SCN9A

2.12e-05393233895391
Pubmed

SCN1A, SCN2A and SCN3A gene polymorphisms and responsiveness to antiepileptic drugs: a multicenter cohort study and meta-analysis.

SCN1A SCN2A

2.12e-05393223859570
Pubmed

Segregation of a mutation in CNGB1 encoding the beta-subunit of the rod cGMP-gated channel in a family with autosomal recessive retinitis pigmentosa.

CNGB3 CNGB1

2.12e-05393211379879
Pubmed

Where is the spike generator of the cochlear nerve? Voltage-gated sodium channels in the mouse cochlea.

SCN2A SCN8A

2.12e-05393216033895
Pubmed

The B3 Subunit of the Cone Cyclic Nucleotide-gated Channel Regulates the Light Responses of Cones and Contributes to the Channel Structural Flexibility.

CNGB3 CNGB1

2.12e-05393226893377
Pubmed

DNAH6 and Its Interactions with PCD Genes in Heterotaxy and Primary Ciliary Dyskinesia.

DNAI1 DNAH5

2.12e-05393226918822
Pubmed

Association of genetic variants in complement factor H and factor H-related genes with systemic lupus erythematosus susceptibility.

CFHR4 CFHR3

2.12e-05393221637784
Pubmed

Experimental and computational evidence that Calpain-10 binds to the carboxy terminus of NaV1.2 and NaV1.6.

SCN2A SCN8A

2.12e-05393238514708
Pubmed

Human Nav1.6 Channels Generate Larger Resurgent Currents than Human Nav1.1 Channels, but the Navβ4 Peptide Does Not Protect Either Isoform from Use-Dependent Reduction.

SCN1A SCN8A

2.12e-05393226182346
Pubmed

De novo SCN1A, SCN8A, and CLCN2 mutations in childhood absence epilepsy.

SCN1A SCN8A

2.12e-05393231054517
Pubmed

Nav1.2 is expressed in caudal ganglionic eminence-derived disinhibitory interneurons: Mutually exclusive distributions of Nav1.1 and Nav1.2.

SCN1A SCN2A

2.12e-05393228784306
Pubmed

Sodium channels SCN1A, SCN2A and SCN3A in familial autism.

SCN1A SCN2A

2.12e-05393212610651
Pubmed

GRP94 is an IGF-1R chaperone and regulates beta cell death in diabetes.

HSP90B2P IGF1R

2.12e-05393238811543
Pubmed

Multidrug resistance in epilepsy and polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, and SCN3A: correlation among phenotype, genotype, and mRNA expression.

SCN1A SCN2A

2.12e-05393218784617
Pubmed

Characterization of 5' untranslated regions of the voltage-gated sodium channels SCN1A, SCN2A, and SCN3A and identification of cis-conserved noncoding sequences.

SCN1A SCN2A

2.12e-05393217544618
Pubmed

Mislocalization of DNAH5 and DNAH9 in respiratory cells from patients with primary ciliary dyskinesia.

DNAI1 DNAH5

2.12e-05393215750039
Pubmed

Mammalian diacylglycerol kinases, a family of lipid kinases with signaling functions.

DGKA DGKG

2.12e-05393210206945
Pubmed

Role of sodium channel subtype in action potential generation by neocortical pyramidal neurons.

SCN2A SCN8A

2.12e-05393229991598
Pubmed

Human voltage-gated sodium channel mutations that cause inherited neuronal and muscle channelopathies increase resurgent sodium currents.

SCN4A SCN9A

2.12e-05393220038812
Pubmed

Role of the hippocampus in Nav1.6 (Scn8a) mediated seizure resistance.

SCN1A SCN8A

2.12e-05393224704313
Pubmed

Gene-to-gene interaction between sodium channel-related genes in determining the risk of antiepileptic drug resistance.

SCN1A SCN2A

2.12e-05393219270815
Pubmed

Association of SCN1A, SCN2A and ABCC2 gene polymorphisms with the response to antiepileptic drugs in Chinese Han patients with epilepsy.

SCN1A SCN2A

2.12e-05393225155934
Pubmed

The sorting receptor Rer1 controls Purkinje cell function via voltage gated sodium channels.

SCN1A SCN8A

2.12e-05393228117367
Pubmed

Chloride channelopathy in myotonic dystrophy resulting from loss of posttranscriptional regulation for CLCN1.

SCN4A DMD

2.12e-05393217135300
Pubmed

Two factor H-related proteins from the mouse: expression analysis and functional characterization.

CFHR4 CFHR3

2.12e-05393217028856
Pubmed

Localization of complement factor H gene expression and protein distribution in the mouse outer retina.

CFHR4 CFHR3

2.12e-05393225684976
Pubmed

Early expression of sodium channel transcripts and sodium current by cajal-retzius cells in the preplate of the embryonic mouse neocortex.

SCN1A SCN2A

2.12e-05393214973256
Pubmed

Expression of alternatively spliced sodium channel alpha-subunit genes. Unique splicing patterns are observed in dorsal root ganglia.

SCN8A SCN9A

2.12e-05393215302875
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

KCNF1 SCN1A SCN4A SCN8A SCN9A

3.72e-0513993516985003
Pubmed

Targeted DNA Sequencing from Autism Spectrum Disorder Brains Implicates Multiple Genetic Mechanisms.

SCN1A SCN2A

4.23e-05493226637798
Pubmed

Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome.

MLH1 CFHR3

4.23e-05493217367211
Pubmed

Dystrophin-deficient cardiomyopathy in mouse: expression of Nox4 and Lox are associated with fibrosis and altered functional parameters in the heart.

CYBB DMD

4.23e-05493218440230
Pubmed

Dorsal root ganglia isolated from Nf1+/- mice exhibit increased levels of mRNA expression of voltage-dependent sodium channels.

SCN1A SCN9A

4.23e-05493222260870
Pubmed

A targeted next-generation sequencing panel reveals novel mutations in Japanese patients with primary ciliary dyskinesia.

DNAI1 DNAH5

4.23e-05493228939216
Pubmed

CFH and CFHR structural variants in atypical Hemolytic Uremic Syndrome: Prevalence, genomic characterization and impact on outcome.

CFHR4 CFHR3

4.23e-05493236793547
Pubmed

Mutations in dynein genes in patients affected by isolated non-syndromic asthenozoospermia.

DNAI1 DNAH5

4.23e-05493218492703
Pubmed

Impaired channel targeting and retinal degeneration in mice lacking the cyclic nucleotide-gated channel subunit CNGB1.

CNGB3 CNGB1

4.23e-05493215634774
Pubmed

Models for discovery of targeted therapy in genetic epileptic encephalopathies.

SCN1A SCN8A

4.23e-05493228742937
Pubmed

Association of sodium voltage-gated channel genes polymorphisms with epilepsy risk and prognosis in the Saudi population.

SCN1A SCN2A

4.23e-05493235801810
Pubmed

DNAI2 mutations cause primary ciliary dyskinesia with defects in the outer dynein arm.

DNAI1 DNAH5

4.23e-05493218950741
Pubmed

Neurexins play a crucial role in cerebellar granule cell survival by organizing autocrine machinery for neurotrophins.

NRXN3 GRIN2C

4.23e-05493235385735
Pubmed

Cyclic nucleotide-gated channel subunit glycosylation regulates matrix metalloproteinase-dependent changes in channel gating.

CNGB3 CNGB1

4.23e-05493224164424
Pubmed

Localization of dystrophin gene transcripts during mouse embryogenesis.

MYL3 DMD

4.23e-0549321429837
Pubmed

Use of recombinant inbred strains for studying genetic determinants of responses to alcohol.

SCN1A SCN2A

4.23e-0549328974318
InteractionSCN4B interactions

SCN1A SCN2A SCN8A

5.07e-068923int:SCN4B
CytobandEnsembl 112 genes in cytogenetic band chrXq26

CT45A8 CT45A6 CT45A1 CT45A3 CT45A10 CT45A5 CT45A2 CT45A7 CT45A9

8.21e-11171939chrXq26
CytobandXq26.3

CT45A6 CT45A1 CT45A3 CT45A5 CT45A2

2.68e-0767935Xq26.3
CytobandEnsembl 112 genes in cytogenetic band chr2q24

PLA2R1 SCN1A SCN2A SCN9A

1.35e-04127934chr2q24
Cytoband2q24.3

SCN1A SCN2A

4.78e-04169322q24.3
Cytoband12q24.31

SETD1B DNAH10 SRSF9

5.91e-048093312q24.31
GeneFamilySodium voltage-gated channel alpha subunits

SCN1A SCN2A SCN4A SCN8A SCN9A

5.91e-1196451203
GeneFamilyDyneins, axonemal

DNAI1 DNAH10 DNAH5 DNAH8

3.28e-0717644536
GeneFamilyEF-hand domain containing|Diacylglycerol kinases

DGKA DGKG DGKD

4.99e-06106431178
GeneFamilyCyclic nucleotide gated channels

CNGB3 CNGB1

5.45e-0410642250
GeneFamilyDEAH-box helicases

DHX16 DHX38

1.43e-0316642500
GeneFamilyPHD finger proteins

SP100 ASH1L BRD1

3.99e-039064388
GeneFamilyPhosphoinositide phosphatases

IMPA1 MTMR2

5.71e-03326421079
GeneFamilyZinc fingers C2H2-type|Lysine methyltransferases|PR/SET domain family

SETD1B ASH1L

6.43e-0334642487
GeneFamilyComplement system|Sushi domain containing

CFHR4 CFHR3

7.19e-0336642492
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_1_CELL

CT45A8 CT45A6 CT45A1 CT45A3 CT45A10 CT45A5 CT45A2 CT45A7 CT45A9

2.85e-1269939M45681
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_MYOFIBROBLAST_2_CELL

CT45A8 CT45A6 CT45A1 CT45A3 CT45A10 CT45A5 CT45A2 CT45A7 CT45A9

1.25e-10104939M45682
CoexpressionGSE11386_NAIVE_VS_MEMORY_BCELL_DN

SYNE1 ASH1L FBXL17 PLEKHA1 KIF13A CBLB

2.16e-05158936M372
CoexpressionGAO_ESOPHAGUS_25W_C1_CILIATED_EPITHELIAL_CELLS

DNAI1 DNAH10 TTLL6 NEK5 SYNE1 FRMPD2 ATP2C2 ARMC2 DNAH5

3.75e-05459939M39136
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAI1 DNAH10 NEK5 SYNE1 FRMPD2 DMD ARMC2 DNAH5

6.78e-09193928ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TMEM132D SYNE1 SCN1A SCN2A ATP2C2 SCN9A DGKG KIF13A

8.62e-0919992819a97e27a4758e794ce7246d295e112b47931a48
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CT45A6 CT45A1 CT45A10 CT45A5 CT45A2 CNGB1 CT45A9

3.76e-08157927b9d04ee417c0d8ea0801d10f1c54e138587009fd
ToppCellwk_15-18-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CT45A6 CT45A1 CT45A10 CT45A5 ROR1 CT45A2 CT45A9

1.39e-07190927d24af6af3271e34afab744352afd28be8a7cc5c3
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CT45A6 CT45A1 CT45A10 CT45A5 MTMR2 CT45A2 CT45A9

1.39e-0719092771a00f63fdd4eb4cc6f190d37e7a0417cdaafacb
ToppCellNS-moderate-d_0-4|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DNAH10 NEK5 FRMPD2 ATP2C2 ARMC2 DNAH5

1.54e-07193927ea345d34440b25f65358a53dc72831998d1c3620
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CT45A6 CT45A1 CT45A10 CT45A5 ROR1 CT45A2 CT45A9

1.54e-071939272f203f6f0c2135acb046c9351a633c3b5b254a46
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH10 TTLL6 NEK5 SYNE1 DMD ARMC2 DNAH5

1.77e-0719792774a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

6.46e-07148926d61123f0c811287843d066b932b4a9ff09c07c5b
ToppCellLPS-antiTNF-Epithelial_airway-Ciliated_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

6.46e-07148926c8e93b87212f55774223caa385859c566fa1981f
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

7.27e-0715192681cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCellLPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

7.27e-071519269cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCellControl-Epithelial_airway-Ciliated_cells-Ciliated|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

8.16e-071549264e3bc24043144143842627cacf6f90dda2228910
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

8.16e-071549269ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellControl-Epithelial_airway-Ciliated_cells|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

8.16e-071549267556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

8.16e-0715492658072ce422d09f2de602580325eaac6c4ec6c136
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

8.47e-071559265f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 DNAH10 TTLL6 FRMPD2 ATP2C2 DNAH5

8.47e-071559260944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 TTLL6 FRMPD2 ATP2C2 DNAH5 JAKMIP2

1.18e-06164926e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCellfacs-Lung-24m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l14|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYBB NRXN3 DGKA DGKG RBKS NOL8

1.40e-06169926813472d429c0b12580b17b440e00a6d8beb7947f
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 DNAH10 OTOGL CNGB3 SCN9A DNAH5

1.40e-0616992612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CT45A6 CT45A1 CT45A10 CT45A5 CT45A2 CT45A9

1.45e-06170926fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN3 ROR1 DGKG DGKD DMD SH3RF3

1.72e-06175926d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN3 OTOGL DGKG DMD DNAH8 SH3RF3

1.72e-06175926316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN3 ROR1 DGKG DGKD DMD SH3RF3

1.72e-06175926454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NRXN3 OTOGL DGKG DMD DNAH8 SH3RF3

1.72e-06175926a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SP100 SYNE1 ASH1L PKN2 PARP14 STAG2

1.90e-0617892601dafd19de04eff459253eaa9a35debf8f3deedf
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

SCN4A PLEKHA1 DGKD PARP14 CBLB ABCB4

1.90e-0617892671ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 OTOGL SCN2A SCN9A DMD DNAH5

2.30e-061849262cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 OTOGL SCN2A SCN9A DMD DNAH5

2.30e-06184926ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 OTOGL SCN2A SCN9A DMD DNAH5

2.30e-061849262b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 NRXN3 SCN1A SCN2A SCN8A DGKG

2.52e-061879267b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC38A1 NRXN3 TMEM132D ATP2C2 SCN9A DMD

2.68e-061899267659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCellCOPD-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAI1 DNAH10 NEK5 FRMPD2 ARMC2 DNAH5

2.68e-061899263e77883db34722b9ce0a03ea74caefc92dc7feff
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAI1 DNAH10 NEK5 SYNE1 FRMPD2 DNAH5

2.94e-06192926be592e661367affced9ebe80849b466e6adb3a34
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 OTOF KCNF1 SCN1A SCN2A SCN8A

3.03e-06193926be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAI1 DNAH10 NEK5 FRMPD2 ARMC2 DNAH5

3.03e-061939260e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellBronchial_Biopsy-Epithelial-Ciliated_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

DNAI1 DNAH10 NEK5 SYNE1 FRMPD2 DNAH5

3.03e-061939260b62a6ddd7c42efd9f39781971d1438501e1fa8d
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 OTOF KCNF1 SCN1A SCN2A SCN8A

3.03e-061939260c652ebe22ce5d2927599dd97ef1920547858395
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 OTOF KCNF1 SCN1A SCN2A SCN8A

3.03e-061939268689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAI1 DNAH10 SYNE1 FRMPD2 ARMC2 DNAH5

3.21e-061959263486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellPSB-critical-LOC-Epithelial-Ciliated|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DNAH10 NEK5 SYNE1 ARMC2 DNAH5

3.40e-061979266865f4831eb23794fb88a8649d48d497bbae3f44
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DNAH10 NEK5 SYNE1 ALDH1L1 DNAH5

3.40e-0619792691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCellNS-moderate-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DNAH10 SYNE1 FRMPD2 ARMC2 DNAH5

3.40e-0619792671fea4aa6ce96c7693fa94792d08770622873850
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DNAH10 NEK5 SYNE1 ALDH1L1 DNAH5

3.40e-0619792622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DNAH10 NEK5 SYNE1 ALDH1L1 DNAH5

3.40e-061979263bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DNAH10 NEK5 SYNE1 ALDH1L1 DNAH5

3.40e-0619792687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellControl_saline-Epithelial_airway|Control_saline / Treatment groups by lineage, cell group, cell type

DNAI1 DNAH10 TTLL6 ATP2C2 DNAH5 JAKMIP2

3.51e-06198926e6863238e022ecfb6a8e3f4b7661b376e92c5d8f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRXN3 SYNE1 SCN1A SCN2A PEG3 SCN8A

3.51e-061989266d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NRXN3 SYNE1 SCN1A SCN2A PEG3 SCN8A

3.51e-061989264ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellControl_saline-Epithelial_airway-airway_epithelial|Control_saline / Treatment groups by lineage, cell group, cell type

DNAI1 DNAH10 TTLL6 ATP2C2 DNAH5 JAKMIP2

3.51e-06198926e7aa42e5fbd42c68f50cda4a8f3aa464c862c007
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

SLC38A1 SP100 OTOF SYNE1 ASH1L PARP14

3.61e-06199926952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SLC38A1 SP100 SYNE1 BRD1 CBLB JAKMIP2

3.71e-06200926d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAI1 DNAH10 OTOF TTLL6 ATP2C2 DNAH5

3.71e-0620092696701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCellLPS_IL1RA-Epithelial_airway-airway_epithelial|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNAI1 DNAH10 TTLL6 ATP2C2 DNAH5 JAKMIP2

3.71e-06200926cf191104484bfb2b9f87de416b9453135f8833c1
ToppCellLPS_IL1RA_TNF-Epithelial_airway-airway_epithelial|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAI1 DNAH10 TTLL6 ATP2C2 DNAH5 JAKMIP2

3.71e-06200926da12821e8a0657869ca0f75d351cce2d7605a505
ToppCellLPS_IL1RA-Epithelial_airway|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

DNAI1 DNAH10 TTLL6 ATP2C2 DNAH5 JAKMIP2

3.71e-06200926a5ae33dd4dc1ff6e1a1eec22c4d523d5ab657607
ToppCellLPS_IL1RA_TNF-Epithelial_airway|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

DNAI1 DNAH10 TTLL6 ATP2C2 DNAH5 JAKMIP2

3.71e-0620092672c1d9eeaed4b3ee6b6c602e8aa29efc2e8744eb
ToppCellE18.5-samps-Mesenchymal-Myofibroblast-MyoFB-1|E18.5-samps / Age Group, Lineage, Cell class and subclass

ATP8B3 DNAH10 TTLL6 SCN9A DNAH5

1.27e-05145925ac41c6c02b7d78162b86222983688f54d04ac47d
ToppCellfacs-Trachea-nan-3m-Myeloid-lymphocyte_of_B_lineage|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYBB SCN4A DGKG DNAH8 ABCB4

1.87e-051579250fecc14959c4c9efc19d5c06475a890e0a30f148
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B3 NRXN3 DNAH10 SCN9A DNAH5

1.93e-05158925f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8B3 NRXN3 DNAH10 SCN9A DNAH5

1.93e-051589258c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellwk_20-22-Mesenchymal-Myofibro_&_SMC-Myofibro_1|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CT45A6 CT45A1 CT45A10 CT45A2 CT45A9

2.05e-051609255cd4fbbd2ce671a8377416eff94041a111375dee
ToppCellLPS-IL1RA-Epithelial_airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAI1 FRMPD2 ATP2C2 DNAH5 JAKMIP2

2.11e-05161925472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-ventral_progenitors_and_neurons_1|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

TMEM132D SCN2A FRMPD2 DGKG DNAH5

2.37e-051659259795ce31689bc63f5a2d68725ef00b23a90c3846
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

SLC38A1 ZGRF1 CNGB3 CBLB JAKMIP2

2.51e-05167925063ec29b32e40aaa138a691da3a79ee8eef0c2be
ToppCell15-Distal-Epithelial-Multiciliated_cell|Distal / Age, Tissue, Lineage and Cell class

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

2.66e-05169925425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DNAH10 NEK5 ARMC2 DNAH5

2.66e-0516992514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

SCN4A ENTPD5 ABCB4 CFHR4 CFHR3

2.82e-05171925c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAI1 DNAH10 NEK5 ARMC2 DNAH5

2.98e-05173925c3762655caa79ac4879876f470d32578a3c93b01
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DNAI1 DNAH10 TTLL6 FRMPD2 DNAH5

3.06e-05174925b8d1c556290d188f56aeefc17f03119686945fe7
ToppCellPCW_10-12-Epithelial-Epithelial_ciliated-epi_ciliated_(14)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DNAI1 DNAH10 TTLL6 FRMPD2 DNAH5

3.06e-0517492500cf27bc23af1472a507be31fba6245a8fdd901b
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

CYBB SLC38A1 SP100 DNAH8 ABCB4

3.23e-05176925d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

3.41e-05178925de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCellCiliated_cells-B-Donor_06|World / lung cells shred on cell class, cell subclass, sample id

DNAH10 TTLL6 NEK5 FRMPD2 DNAH5

3.60e-05180925bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 NRXN3 SCN1A SCN2A DGKG

3.60e-05180925f6a2208960d0df1500c974cc44c3c054cd7475a9
ToppCell3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC38A1 TES SCN2A DGKG CFHR4

3.69e-05181925beb2771820956be8b190c0088ae3c4efdb53c897
ToppCellControl-Epithelial_cells-Airway_ciliated|Control / group, cell type (main and fine annotations)

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

3.79e-05182925fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)-|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

3.89e-05183925b1336eac5adbffade4cef3e0ce3de75a781ae365
ToppCell367C-Epithelial_cells-Epithelial-F_(Ciliated)|367C / Donor, Lineage, Cell class and subclass (all cells)

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

3.89e-05183925cc57dcb59c68d68a546dc108dd9e009b2aab8da5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAI1 DNAH10 TTLL6 NEK5 DNAH5

3.99e-05184925264e14aa1859cfc0ed5fb40e97ea189aed9ef4a5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAI1 DNAH10 TTLL6 NEK5 DNAH5

3.99e-05184925d7eccbd21c480d907fdc8eff2bf5ae22ae452221
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAI1 DNAH10 TTLL6 NEK5 DNAH5

3.99e-0518492522010cfe0428ebfa40952cc1a1a12ad3d25b35c9
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 NRXN3 SCN1A SCN2A DGKG

4.10e-0518592570de48988c1f8e0809afc8092b663aa439d8e528
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

4.10e-051859255e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

4.10e-05185925f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

4.10e-051859253e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCellCOVID-19-Epithelial_cells-Airway_ciliated|COVID-19 / group, cell type (main and fine annotations)

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

4.10e-0518592518a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-24m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 SCN2A DGKG GRIN2C CAMTA1

4.21e-05186925d1d01ce46e62944aa9864eda47e8401b5f0d2bdc
ToppCellNS-critical-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

4.21e-0518692576033438426d8f9c72cd6691a7baf92104c9f03d
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CYBB OTOGL TOPAZ1 SCN2A DNAH8

4.21e-0518692523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellSubstantia_nigra-Neuronal-Inhibitory|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

NRXN3 GLG1 PEG3 SCN9A CAMTA1

4.21e-051869259d3efe2a4feea2bc205a7e45b9b9f9ed9b3609ce
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-Granular_Neuron_CB_Gabra6|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC38A1 NRXN3 SCN2A SCN8A DGKG

4.21e-05186925d6c8ce2a32c218dcc63d861cc247152430ed3c8c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OTOF KCNF1 SCN1A SCN2A SCN8A

4.21e-051869257278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellfacs-Lung-EPCAM-3m-Epithelial-Ciliated_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 TTLL6 NEK5 ATP2C2 DNAH5

4.31e-0518792504dba2ed09ee4180830bdf0191921696697ea234
ToppCellCOPD-Epithelial-Ciliated|COPD / Disease state, Lineage and Cell class

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

4.31e-05187925f0fd0792f6926f705d175f6e6fd480f12c7a3bd4
ToppCellFetal_29-31_weeks-Epithelial-ciliated_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

4.31e-051879259e10ed56090d82589bc457788282f664b70ace4b
ToppCellfacs-Lung-EPCAM-3m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 TTLL6 NEK5 ATP2C2 DNAH5

4.31e-05187925805dafe22f835ece4dd091d8030d0a63b52a48dd
ToppCellEpithelial-Epithelial-D_(Ciliated)|Epithelial / shred on cell class and cell subclass (v4)

DNAH10 TTLL6 NEK5 SYNE1 DNAH5

4.42e-051889258f30535a32968a81a304315a49c0d90a77d36948
ToppCellCiliated_cells-B-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

DNAI1 DNAH10 NEK5 FRMPD2 DNAH5

4.42e-05188925606907c865bd2f11bb6474932716550f7723d858
DrugZonisamide

SCN1A SCN2A SCN4A SCN9A

4.99e-0717894DB00909
DrugAPETx1, Anthopleura elegantissima

SCN2A SCN4A SCN8A

1.15e-066893ctd:C475726
Drugpotassium

SLC38A1 ATP8B3 PLA2R1 KLK6 MYL3 IMPA1 KCNF1 SYNE1 SCN2A SCN4A ATP2C2 SCN9A MLH1 PKN2 GRIN2C CNGB1

1.63e-0610088916CID000000813
DrugAC1L1IZE

DNAI1 IGF1R DNAH10 ATP2C2 DNAH5 DNAH8

1.27e-05131896CID000004799
Drugmu-conotoxin KIIIA, Conus kinoshitai

SCN2A SCN4A

1.51e-052892ctd:C502265
DrugTetrodotoxin

CYBB SCN2A SCN8A SCN9A

1.79e-0540894ctd:D013779
DrugBiliton

DNAI1 DNAH10 DNAH5 DNAH8

1.98e-0541894CID000002974
DrugAC1L4Q08

DGKA DGKG DGKD

2.54e-0515893CID000161747
DrugIC261

DNAI1 DNAH10 DNAH5 DNAH8 ABCB4

3.76e-0596895CID000003674
Drug1,2-dicaprin

DGKA DGKG DGKD PKN2

4.04e-0549894CID000001321
DrugScorpion Venoms

SCN2A SCN4A SCN9A

4.52e-0518893ctd:D012604
DrugN-(2-methyl-3-(4-(4-(4-(trifluoromethoxy)benzyloxy)piperidin-1-yl)-1,3,5-triazin-2-ylamino)phenyl)acetamide

SCN4A SCN9A

4.52e-053892ctd:C561228
Drugmagnesium

DNAI1 KLK6 IMPA1 DNAH10 ATP2C2 ENTPD5 MLH1 DGKA DGKG DGKD RBKS PKN2 GRIN2C DNAH5 DNAH8 ABCB4

4.96e-0513258916CID000000888
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN1A SCN2A SCN4A SCN8A SCN9A

3.88e-1110835DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN1A SCN2A SCN4A SCN8A SCN9A

3.88e-1110835DOID:0080422 (implicated_via_orthology)
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN1A SCN2A SCN4A SCN8A SCN9A

1.22e-1012835DOID:0060170 (implicated_via_orthology)
Diseaseanxiety disorder (implicated_via_orthology)

SCN1A SCN2A SCN9A TSC2

4.10e-0722834DOID:2030 (implicated_via_orthology)
DiseaseEpilepsy

SCN1A SCN2A SCN8A SCN9A TSC2 DDX3X

6.63e-07109836C0014544
DiseaseGeneralized Epilepsy with Febrile Seizures Plus

SCN1A SCN2A SCN9A

1.78e-069833C3502809
DiseaseEpilepsy, Cryptogenic

SCN1A SCN2A SCN8A TSC2 DDX3X

3.59e-0682835C0086237
DiseaseAwakening Epilepsy

SCN1A SCN2A SCN8A TSC2 DDX3X

3.59e-0682835C0751111
DiseaseAura

SCN1A SCN2A SCN8A TSC2 DDX3X

3.59e-0682835C0236018
DiseaseInfantile Severe Myoclonic Epilepsy

SCN1A SCN2A SCN9A

6.01e-0613833C0751122
DiseaseNeurodevelopmental Disorders

SCN1A SCN2A SCN8A ASH1L DDX3X

6.67e-0693835C1535926
Diseaseepilepsy (implicated_via_orthology)

SCN1A SCN2A SCN4A SCN8A SCN9A GRIN2C

6.88e-06163836DOID:1826 (implicated_via_orthology)
DiseaseEarly Infantile Epileptic Encephalopathy 6

SCN1A SCN9A

7.82e-062832C4551549
DiseaseB Virus Infection

SCN8A SCN9A

2.34e-053832C0037140
DiseaseBenign familial infantile epilepsy

SCN2A SCN8A

2.34e-053832cv:C5575231
DiseasePostherpetic neuralgia

SCN8A SCN9A

2.34e-053832C0032768
DiseaseHerpesviridae Infections

SCN8A SCN9A

2.34e-053832C0019372
Diseasewaist circumference

NRXN3 DNAH10 DGKG ALDH1L1 DMD CBLB DNAH5 PURG

2.85e-05429838EFO_0004342
DiseaseNADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial measurement

CFHR4 CFHR3

4.67e-054832EFO_0803292
DiseaseKartagener syndrome (is_implicated_in)

DNAI1 DNAH5

4.67e-054832DOID:0050144 (is_implicated_in)
Diseaseinterleukin 5 measurement

NRXN3 TTLL6 SH3RF3

6.68e-0528833EFO_0008185
Diseaseglucose metabolism disease (implicated_via_orthology)

IGF1R DGKA DGKG

6.68e-0528833DOID:4194 (implicated_via_orthology)
Diseaseautism spectrum disorder (implicated_via_orthology)

NRXN3 SCN1A SCN2A ASH1L TSC2

7.13e-05152835DOID:0060041 (implicated_via_orthology)
DiseaseCerebellar Ataxia

SYNE1 SCN8A

7.77e-055832C0007758
DiseaseFamilial benign neonatal epilepsy

SCN2A SCN8A

1.16e-046832C0220669
DiseaseColorectal Carcinoma

SYNE1 FRMPD2 PEG3 MLH1 ALDH1L1 DMD JAKMIP2 DNAH8 ABCB4

1.59e-04702839C0009402
DiseaseSeizure, Febrile, Simple

SCN1A SCN2A

1.63e-047832C0149886
DiseaseSeizure, Febrile, Complex

SCN1A SCN2A

1.63e-047832C0751057
DiseaseLewy body dementia (is_implicated_in)

KLK6 IGF1R

1.63e-047832DOID:12217 (is_implicated_in)
DiseaseEarly Childhood Epilepsy, Myoclonic

SCN1A SCN9A

2.16e-048832C0393695
DiseaseIdiopathic Myoclonic Epilepsy

SCN1A SCN9A

2.16e-048832C0338478
DiseaseSymptomatic Myoclonic Epilepsy

SCN1A SCN9A

2.16e-048832C0338479
DiseaseBenign Infantile Myoclonic Epilepsy

SCN1A SCN9A

2.16e-048832C0751120
DiseaseMyoclonic Encephalopathy

SCN1A SCN9A

2.16e-048832C0438414
DiseaseMyoclonic Absence Epilepsy

SCN1A SCN9A

2.16e-048832C0393703
DiseaseCiliopathies

CRELD1 TSC2 DNAH5 DNAH8

2.68e-04110834C4277690
DiseaseFebrile Convulsions

SCN1A SCN2A

2.78e-049832C0009952
DiseaseAtypical hemolytic-uremic syndrome

CFHR4 CFHR3

2.78e-049832cv:C2931788
DiseaseHemolytic-uremic syndrome

CFHR4 CFHR3

2.78e-049832cv:C0019061
DiseaseMyoclonic Epilepsy

SCN1A SCN9A

2.78e-049832C0014550
DiseaseDrug habituation

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C0013170
DiseaseDrug abuse

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C0013146
DiseasePrescription Drug Abuse

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C4316881
DiseaseSubstance-Related Disorders

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C0236969
DiseaseDrug Use Disorders

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C0013222
DiseaseDrug Dependence

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C1510472
DiseaseSubstance Dependence

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C0038580
DiseaseSubstance Use Disorders

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C0038586
DiseaseOrganic Mental Disorders, Substance-Induced

PLA2R1 NRXN3 SYNE1 DNAH8

3.17e-04115834C0029231
DiseaseSubstance abuse problem

PLA2R1 NRXN3 SYNE1 DNAH8

3.28e-04116834C0740858
DiseaseEpilepsy, Myoclonic, Infantile

SCN1A SCN9A

3.47e-0410832C0917800
DiseaseBipolar Disorder

IMPA1 SYNE1 SCN2A ROR1 SCN8A BRD1 DNAH8

3.98e-04477837C0005586
Diseasevisceral adipose tissue measurement

NRXN3 DNAH10 FBXL17 DGKG SRSF9 HMGCLL1 PURG

4.18e-04481837EFO_0004765
DiseaseMyoclonic Astatic Epilepsy

SCN1A SCN9A

4.23e-0411832C0393702
DiseaseKartagener syndrome (implicated_via_orthology)

DNAI1 DNAH5

6.96e-0414832DOID:0050144 (implicated_via_orthology)
Diseaserosacea severity measurement

IGF1R NRXN3 PKN2 CAMTA1

8.01e-04147834EFO_0009180
DiseaseMMR-related febrile seizures

SCN1A SCN2A

8.02e-0415832EFO_0006519
Diseasethyroid volume

IGF1R DNAH5

9.14e-0416832EFO_0004865
DiseaseEarly infantile epileptic encephalopathy with suppression bursts

SCN1A SCN2A

9.14e-0416832C0393706
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN1A SCN2A

1.16e-0318832HP_0002373
Diseasefacial asymmetry measurement

NRXN3 ROR1

1.30e-0319832EFO_0009751
Diseasecomplement factor H-related protein 3 measurement

DMD SH3RF3 CFHR4 CFHR3

1.34e-03169834EFO_0600056
DiseaseLung diseases

DNAI1 IGF1R DNAH5

1.40e-0378833C0024115
DiseaseIntellectual Disability

SYNE1 SCN1A SCN8A ASH1L STAG2 DDX3X

1.65e-03447836C3714756
DiseaseBronchiectasis

DNAI1 DNAH5

1.74e-0322832C0006267
DiseaseWest Syndrome

SCN2A TSC2

2.07e-0324832C0037769
Diseasebirth weight, parental genotype effect measurement

SLC38A1 IGF1R PLEKHA1 ARMC2

2.14e-03192834EFO_0004344, EFO_0005939
Diseasecognitive function measurement

SLC38A1 NRXN3 SCN2A CNGB3 MTMR2 FBXL17 PLEKHA1 DNAH5 SH3RF3 SRSF9 PURG

2.23e-0314348311EFO_0008354
Diseasediet measurement

SLC38A1 NRXN3 SCN2A MTMR2 DGKG CAMTA1 DNAH5 CNGB1 PURG

2.74e-031049839EFO_0008111
Diseasebody weight

SLC38A1 CRELD1 IGF1R NRXN3 FBXL17 DGKG PLEKHA1 DMD CPSF2 PURG

2.81e-0312618310EFO_0004338

Protein segments in the cluster

PeptideGeneStartEntry
YGDVEMKNGVCRKES

BRD1

401

O95696
GLYKDEGLMIQCDKC

ASH1L

2591

Q9NR48
DHMKLKVQGVECLYG

CAMTA1

136

Q9Y6Y1
ECCRAFGGKDIKVYM

CPSF2

576

Q9P2I0
QLCTAMEQYKGDKDV

ARMC2

476

Q8NEN0
CVGQKYEKIFEMLEG

CT45A5

136

P0DMU8
VIYAGFDTKIMKNCG

ATP8B3

351

O60423
MFLVGTEEGKIYKCS

DNAI1

511

Q9UI46
MCQQVYARKEALKGG

DMD

1141

P11532
LFEEGYTNKGMKIAC

DHX16

436

O60231
CVGQKYEKIFEMLEG

CT45A7

136

P0DMV0
MNAVEEGKGIFYNIK

ATP2C2

716

O75185
VRKYMQKEGCAGEVV

KIAA0895L

226

Q68EN5
AELMQQFDVIYGKCG

MORC1

181

Q86VD1
MVCKVGKDSFGNDYI

RBKS

71

Q9H477
MERGKIGLDFCKYLV

DDX3X

331

O00571
ICAEGYKQMEGICVK

CRELD1

331

Q96HD1
KQDKICLMAGGYEVI

HSP90B2P

191

Q58FF3
GVSALQIYCMKEGVK

JAKMIP2

611

Q96AA8
SDMEQFCKIKGYLEE

JAKMIP2

686

Q96AA8
MIDYEKGGILKVEDF

ENTPD5

341

O75356
KCEMKITYGQCGDVL

MYL3

66

P08590
CLGRKYEKIFEMLEG

CT45A10

136

P0DMU9
IAKLMGEGYAFEEVK

CBLB

936

Q13191
GMVYEGVAKGVVKDE

IGF1R

1011

P08069
MDKYDVIKAIGQGAF

NEK5

1

Q6P3R8
CVGQKYEKIFEMLEG

CT45A3

136

Q8NHU0
TKDMGRCLGKYVVVF

DNAH8

1856

Q96JB1
FMGCLKEVVYKNNDI

NRXN3

401

Q9Y4C0
LKLFEDGEMAKYVQG

DGKA

31

P23743
GQKELYLEACKLMGV

LRRC74A

81

Q0VAA2
GENIKDMAKDVTYIC

MTMR2

81

Q13614
QAFKGVGCLYEKESM

NOL8

571

Q76FK4
YGKEKMYECKVCGET

PEG3

621

Q9GZU2
CYGRGNVTMDEIKKA

ABCB4

491

P21439
CYIELQENEVMKEGG

PARP14

771

Q460N5
DGCVSAKGELVMQYK

DGKG

411

P49619
EIKECADEPVGKGYM

GLG1

186

Q92896
CVGQKYEKIFEMLEG

CT45A1

136

Q5HYN5
CVGQKYEKIFEMLEG

CT45A9

136

P0DMV2
YAKTGDTIEFMCKLG

CFHR3

291

Q02985
EEMALGICAKGVIVY

FRMPD2

561

Q68DX3
FGQCYKISDEGMIVI

FBXL17

471

Q9UF56
CVGQKYEKIFEMLEG

CT45A2

136

Q5DJT8
KTGDTIEFMCKLGYN

CFHR4

541

Q92496
CVGQKYEKIFEMLEG

CT45A8

136

P0DMV1
GFKMEVGQYIFVKCP

CYBB

316

P04839
KCVMNNYFGIGLDAK

DGKD

761

Q16760
GMLKFVEAVMGYCDV

DNAH10

3236

Q8IVF4
CVGQKYEKIFEMLEG

CT45A6

136

P0DMU7
KDMGRCLGKYVVVFN

DNAH5

1991

Q8TE73
TECKMNEGIVKLYNE

OTOGL

2241

Q3ZCN5
MDPVVCVEVGDDKKY

OTOF

271

Q9HC10
GENFIKYEEEMRKIC

PURG

311

Q9UJV8
EMSGIKVGDDKCYLV

KIF13A

436

Q9H1H9
LYKVMEAGDFICKAV

HMGCLL1

341

Q8TB92
VVMECGLDVKYFKPG

RTN4IP1

126

Q8WWV3
AGEIYVMVNDKPVCK

TES

336

Q9UGI8
DVCYADVQKDGVGMV

SRSF9

136

Q13242
VVGMQLFGKSYKECV

SCN4A

716

P35499
KMLSNFGDCVQYKEI

SYNE1

1226

Q8NF91
CDYVFVNGKEMKGKV

TMEM132D

486

Q14C87
KIEFGVVYSCVEGKM

IMPA1

116

P29218
AVVGMQLFGKSYKEC

SCN9A

881

Q15858
ENFLRDMCKKYGEVE

SETD1B

116

Q9UPS6
CLEMDIKAQGYKVFS

KCTD14

216

Q9BQ13
VYDECKEGVAKMDQI

PGBD1

731

Q96JS3
VKIADFGLCKEGMGY

PKN2

796

Q16513
IGCEDKTLAFKMNGY

MLH1

231

P40692
DCGKEGYGFVCEKMQ

PLA2R1

1086

Q13018
VVGMQLFGKSYKDCV

SCN1A

906

P35498
VKLMEYCQHGVKEGA

ALDH1L1

756

O75891
NDYVCKKGEIGREMY

CNGB1

986

Q14028
KVDLFKGCDTQMIYD

CNGB3

521

Q9NQW8
MEELGECAFGKIYKG

ROR1

476

Q01973
MFEIKKICCIGAGYV

UGDH

1

O60701
VCLSGFLDEVMKKYG

SENP5

501

Q96HI0
CNYKLLKTGIENGDM

STAG2

711

Q8N3U4
HKGEMYRVLEKCQDG

SH3RF3

486

Q8TEJ3
CGGYTLKVLMENKFL

SP100

661

P23497
AVVGMQLFGKSYKEC

SCN2A

896

Q99250
VVGMQLFGKSYKECV

SCN8A

891

Q9UQD0
GIMFVIDSGYCKLKV

DHX38

816

Q92620
VKEIKPGEDMICQLY

TTLL6

191

Q8N841
GDEKVCMDVFKKYIN

TOPAZ1

1121

Q8N9V7
NLILRGGMKFYECKE

ZNF621

141

Q6ZSS3
KTYVGFDMGICKTEN

ZGRF1

616

Q86YA3
AVIKAGYCVKQGAVM

PLEKHA1

191

Q9HB21
EEEVNYLFNGVKKMG

TERB1

676

Q8NA31
SKETGCMVYEKLGEQ

SLC38A1

126

Q9H2H9
DKTKQREMVYCLEQG

TSC2

781

P49815
ITQNMLCAGDEKYGK

KLK6

176

Q92876
EVYYFGEVHMKKGIC

KCNF1

91

Q9H3M0
NLVKKAIYAMVEGDC

NAA30

301

Q147X3
AVLNYMAGKDEGCKL

GRIN2C

731

Q14957