Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal pulmonary circulation

DPP4 HSPG2 NPR1 LMF1 ASH1L PRDX6 FGFR2

2.12e-06691217MP:0002295
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DOC2A HSPG2 PDE4A TMEM8B POLE CYB561D2 CHD8 EDC4 FBXL19 RALGAPA2 MAST2 TAOK2 SLC8B1 RPAP1 ZBED4 KLHL21 HPS6 PKD1 USP40 LRP4 ZNRF1 FGFR2 ATG9A WDR24

5.00e-1011051642435748872
Pubmed

The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

CHST5 IZUMO4 C6orf89 DHRS13 CDH23 PGLYRP2 TLR9 CDCP1 TAOK2 QSOX1 NTNG2 LCTL CCNL1 ITPRIP WFDC5 CHPF2 ADGRF3 TMEM231

1.06e-069851641812975309
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

SLC5A7 CDH23 RNASEK IDE EDC4 MAST2 CERT1 PRDX6 RETREG3 AMZ2 PITPNM1 EFNA1 DENND1B KLHL21 SLC5A6 RNASEH2C OGFOD1 PRMT7 PLXNB3

6.95e-0612421641930973865
Pubmed

Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.

TRIM46 CCNL2 ASH1L CHD8 FAM117B DELE1 MAST2 TENT5B AMZ2 TAOK2 MYG1 TCAIM PKD1 TENM1 FGFR2 B4GALNT3 C6orf141 CFAP46

1.89e-0512151641815146197
Pubmed

Pathogenesis of presbycusis in animal models: a review.

CDH23 TYR

2.21e-052164221211561
Pubmed

Protein kinase D1 mediates synergistic MMP-3 expression induced by TNF-α and bradykinin in human colonic myofibroblasts.

PKD1 MMP3

2.21e-052164221867693
Pubmed

VARS2 V552V variant as prognostic marker in patients with early breast cancer.

POLE VARS2

2.21e-052164220503108
Pubmed

Usherin is required for maintenance of retinal photoreceptors and normal development of cochlear hair cells.

CDH23 USH2A

2.21e-052164217360538
Pubmed

Recessive mutation in a standard recombinant-inbred line of mice affects seminal vesicle shape.

TYR FGFR2

2.21e-05216423181757
Pubmed

Hypopigmentation and maternal-zygotic embryonic lethality caused by a hypomorphic mbtps1 mutation in mice.

MBTPS1 TYR

2.21e-052164222540041
Pubmed

Regulation of somatostatin receptor 4-mediated cytostatic effects by CD26 in malignant pleural mesothelioma.

DPP4 SSTR4

2.21e-052164224743707
Pubmed

The CD318/CD6 axis limits type 1 diabetes islet autoantigen-specific human T cell activation.

CDCP1 CD6

2.21e-052164238642507
Pubmed

Targeting tetramer-forming GABPβ isoforms impairs self-renewal of hematopoietic and leukemic stem cells.

GABPB2 GABPB1

2.21e-052164222862946
Pubmed

CD318 is a ligand for CD6.

CDCP1 CD6

2.21e-052164228760953
Pubmed

A new murine lymphocyte alloantigen, Ly-21.2, mapping to the seventh chromosome.

ITGAL TYR

2.21e-05216426802749
Pubmed

Precise mapping of the gene for Ly-21.2 on the 7th chromosome.

ITGAL TYR

6.61e-05316427161508
Pubmed

CDK13/CDC2L5 interacts with L-type cyclins and regulates alternative splicing.

CCNL2 CCNL1

6.61e-053164217261272
Pubmed

Targeted expression of stromelysin-1 in mammary gland provides evidence for a role of proteinases in branching morphogenesis and the requirement for an intact basement membrane for tissue-specific gene expression.

MMP3 MMP11

6.61e-05316428175886
Pubmed

Polycystin-1 is required for stereocilia structure but not for mechanotransduction in inner ear hair cells.

CDH23 PKD1

6.61e-053164221865467
Pubmed

Characterization of cyclin L1 as an immobile component of the splicing factor compartment.

CCNL2 CCNL1

6.61e-053164217494991
Pubmed

Characterization of cyclin L1 and L2 interactions with CDK11 and splicing factors: influence of cyclin L isoforms on splice site selection.

CCNL2 CCNL1

6.61e-053164218216018
Pubmed

Secretin deficiency causes impairment in survival of neural progenitor cells in mice.

TYR SCTR

6.61e-053164221159798
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

SPNS1 MBOAT7 TMEM8B ASH1L CH25H RNASEK QSOX1 NTNG2 SLC5A6 MRAP PKD1 TMEM231

1.26e-046971641228298427
Pubmed

Gene mapping of mouse IL-4 receptor: the loci of interleukin 4 (IL-4) receptor gene and lymphocyte function associated antigen 1 (LFA-1) gene are closely linked on chromosome 7.

ITGAL TYR

1.32e-04416421680807
Pubmed

CDK11(p58) kinase activity is required to protect sister chromatid cohesion at centromeres in mitosis.

CCNL2 CCNL1

1.32e-044164224436071
Pubmed

Redundancy of human ATG4 protease isoforms in autophagy and LC3/GABARAP processing revealed in cells.

ATG4C ATG4D

1.32e-044164230661429
Pubmed

Association of self-DNA mediated TLR9-related gene, DNA methyltransferase, and cytokeratin protein expression alterations in HT29-cells to DNA fragment length and methylation status.

TLR9 DNMT3B

1.32e-044164224459426
Pubmed

Increased expression of a 58-kDa protein kinase leads to changes in the CHO cell cycle.

CCNL2 CCNL1

1.32e-04416422217177
Pubmed

Impact of viral and host DNA methylations on HPV16-related cervical cancer pathogenesis.

TLR9 DNMT3B

1.32e-044164228459195
Pubmed

FGFR2, FGF8, FGF10 and BMP7 as candidate genes for hypospadias.

BMP7 FGFR2

1.32e-044164217264867
Pubmed

The mouse frizzy mutation (fr) maps between D7Csu5 and D7Mit165.

TYR FGFR2

1.32e-044164218177347
Pubmed

Assignment of genes to regions of mouse chromosomes.

TYR HPS6

1.32e-0441642273256
Pubmed

CCND1, NOP14 and DNMT3B are involved in miR-502-5p-mediated inhibition of cell migration and proliferation in bladder cancer.

NOP14 DNMT3B

1.32e-044164231971654
Pubmed

Aberrant methylation of ATG2B, ATG4D, ATG9A and ATG9B CpG island promoter is associated with decreased mRNA expression in sporadic breast carcinoma.

ATG9A ATG4D

1.32e-044164227265029
Pubmed

Delipidation of mammalian Atg8-family proteins by each of the four ATG4 proteases.

ATG4C ATG4D

1.32e-044164229458288
Pubmed

Coordinate expression of matrix metalloproteinase family members in the uterus of normal, matrilysin-deficient, and stromelysin-1-deficient mice.

MMP3 MMP11

1.32e-04416429348221
Pubmed

Bone morphogenetic proteins protect pulmonary microvascular endothelial cells from apoptosis by upregulating α-B-crystallin.

CRYAB BMP7

1.32e-044164224072698
Pubmed

Cyclooxygenase-1 and -2 differentially modulate lipopolysaccharide-induced blood-brain barrier disruption through matrix metalloproteinase activity.

PTGS1 MMP3

1.32e-044164219844242
Pubmed

TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.

HSPG2 CDCP1 CRYAB QSOX1 CHPF2 TMEM131

1.34e-04164164632409323
Pubmed

Dopamine and glutamate induce distinct striatal splice forms of Ania-6, an RNA polymerase II-associated cyclin.

CCNL2 CCNL1

2.19e-045164211683997
Pubmed

Heparanase localization during palatogenesis in mice.

HSPG2 MMP3

2.19e-045164223509775
Pubmed

Bmp6 and Bmp7 are required for cushion formation and septation in the developing mouse heart.

BMP7 DHH

2.19e-045164211437450
Pubmed

Genetic variations in the fine structure and ontogeny of mouse melanin granules.

TYR HPS6

2.19e-04516425902512
Pubmed

Kinetics comparisons of mammalian Atg4 homologues indicate selective preferences toward diverse Atg8 substrates.

ATG4C ATG4D

2.19e-045164221177865
Pubmed

Spontaneous mutation in mice provides new insight into the genetic mechanisms that pattern the seminal vesicles and prostate gland.

TYR FGFR2

2.19e-045164212666202
Pubmed

Heparanase cleavage of perlecan heparan sulfate modulates FGF10 activity during ex vivo submandibular gland branching morphogenesis.

HSPG2 FGFR2

2.19e-045164217959718
Pubmed

Transcriptional up-regulation of the delayed early gene HRS/SRp40 during liver regeneration. Interactions among YY1, GA-binding proteins, and mitogenic signals.

GABPB2 GABPB1

2.19e-04516429857059
Pubmed

A twelfth linkage group of the house mouse.

TYR HPS6

2.19e-045164218890162
Pubmed

Intracellular MMP3 Promotes HSP Gene Expression in Collaboration With Chromobox Proteins.

CRYAB MMP3

2.19e-045164227206651
Pubmed

CDK11(p58) protein kinase activity is associated with Bcl-2 down-regulation in pro-apoptosis pathway.

CCNL2 CCNL1

2.19e-045164217516030
Pubmed

Inflammation-dependent overexpression of c-Myc enhances CRL4DCAF4 E3 ligase activity and promotes ubiquitination of ST7 in colitis-associated cancer.

HSPG2 NEIL2 ASH1L CDH23 CDCP1 PRDX6 FGFR2

2.30e-04257164730945288
Pubmed

A genetic association study of maternal and fetal candidate genes that predispose to preterm prelabor rupture of membranes (PROM).

HSPG2 NPR1 TLR9 PTGS1 MMP3 MMP11

2.64e-04186164620673868
Pubmed

Identification of fetal and maternal single nucleotide polymorphisms in candidate genes that predispose to spontaneous preterm labor with intact membranes.

HSPG2 NPR1 TLR9 PTGS1 MMP3 MMP11

2.64e-04186164620452482
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

CCNL2 MAP1A ASH1L CHD8 RALGAPA2 MAST2 SLC4A1 FAM120A EML5 ZFHX4 KLHL21 LRP4 CHPF2 TIGD5 ANAPC4

2.76e-0411161641531753913
Pubmed

Genomic analysis of mouse retinal development.

SPNS1 HJURP RNASEK MAST2 TAOK2 BMP7 FAM120A ZFHX4 CLEC11A RNASEH2C PKD1 ZNRF1 FGFR2 PRMT7

3.14e-0410061641415226823
Pubmed

Rectification of muscle and nerve deficits in paralyzed ryanodine receptor type 1 mutant embryos.

RYR3 LRP4

3.27e-046164226025922
Pubmed

PRMT7 Preserves Satellite Cell Regenerative Capacity.

PRMT7 DNMT3B

3.27e-046164226854227
Pubmed

The effect of epidermal growth factor on matrix metalloproteinases and tissue inhibitors of metalloproteinase gene expression in cultured human gingival fibroblasts.

MMP3 MMP11

3.27e-046164217181997
Pubmed

Adipocyte Accumulation in the Bone Marrow during Obesity and Aging Impairs Stem Cell-Based Hematopoietic and Bone Regeneration.

DPP4 TYR

3.27e-046164228330582
Pubmed

YEAF1/RYBP and YAF-2 are functionally distinct members of a cofactor family for the YY1 and E4TF1/hGABP transcription factors.

GABPB2 GABPB1

3.27e-046164211953439
Pubmed

The BRAF oncoprotein functions through the transcriptional repressor MAFG to mediate the CpG Island Methylator phenotype.

CHD8 DNMT3B

3.27e-046164225219500
Pubmed

Cloning of wrinkle-free, a previously uncharacterized mouse mutation, reveals crucial roles for fatty acid transport protein 4 in skin and hair development.

NTNG2 MED27

3.27e-046164212697906
Pubmed

Partial Rescue of Ocular Pigment Cells and Structure by Inducible Ectopic Expression of Mitf-M in MITF-Deficient Mice.

RDH5 TYR

3.27e-046164230590377
Pubmed

Matrix metalloproteinase activity in pediatric acute lung injury.

MMP3 MMP11

3.27e-046164219159011
Pubmed

ATG4 family proteins drive phagophore growth independently of the LC3/GABARAP lipidation system.

ATG4C ATG4D

3.27e-046164233773106
Pubmed

Use of two-dimensional electrophoresis to identify and map new mouse genes.

PRDX6 TYR

3.27e-0461642447069
Pubmed

Cell-surface proteomics identifies lineage-specific markers of embryo-derived stem cells.

DPP4 CDCP1 FGFR2

3.44e-0429164322424930
Pubmed

Biochemical characterization of native Usher protein complexes from a vesicular subfraction of tracheal epithelial cells.

CDH23 USH2A

4.57e-047164220058854
Pubmed

Multidimensional prognostic risk assessment identifies association between IL12B variation and surgery in Crohn's disease.

LDHD ZNRF1

4.57e-047164223665963
Pubmed

The MuSK activator agrin has a separate role essential for postnatal maintenance of neuromuscular synapses.

TYR LRP4

4.57e-047164225368159
Pubmed

HIV-1 viral infectivity factor interacts with microtubule-associated protein light chain 3 and inhibits autophagy.

ATG4C ATG4D

4.57e-047164225490467
Pubmed

The G protein-coupled receptor repertoires of human and mouse.

GLP2R SCTR ADGRF3 GPR151

5.44e-0479164412679517
Pubmed

Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects.

CHST5 LDHD ZNRF1

6.03e-0435164319844255
Pubmed

Microarray-based mutation analysis of 183 Spanish families with Usher syndrome.

CDH23 USH2A

6.07e-048164219683999
Pubmed

Molecular mapping of the tubby (tub) mutation on mouse chromosome 7.

ITGAL TYR

6.07e-04816428833147
Pubmed

Roles of Mis18α in epigenetic regulation of centromeric chromatin and CENP-A loading.

HJURP DNMT3B

6.07e-048164222516971
Pubmed

Association and mutation analyses of 16p11.2 autism candidate genes.

DOC2A TAOK2

6.07e-048164219242545
Pubmed

UMD-USHbases: a comprehensive set of databases to record and analyse pathogenic mutations and unclassified variants in seven Usher syndrome causing genes.

CDH23 USH2A

6.07e-048164218484607
Pubmed

Molecular basis of human Usher syndrome: deciphering the meshes of the Usher protein network provides insights into the pathomechanisms of the Usher disease.

CDH23 USH2A

6.07e-048164216545802
Pubmed

Expression and function of matrix metalloproteinases and their inhibitors at the maternal-embryonic boundary during mouse embryo implantation.

MMP3 MMP11

6.07e-04816428674412
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MBTPS1 LMF1 SRD5A3 TMEM8B FAM53A ASH1L FAM117B IDE CERT1 PRDX6 EFNA1 SLC8B1 DENND1B FAM120A TESMIN USP40 MED27

7.03e-0414891641728611215
Pubmed

The Effects of Genotype and Cell Environment on Melanoblast Differentiation in the House Mouse.

TYR HPS6

7.79e-049164217247639
Pubmed

Characterization of cyclin L2, a novel cyclin with an arginine/serine-rich domain: phosphorylation by DYRK1A and colocalization with splicing factors.

CCNL2 CCNL1

7.79e-049164214623875
Pubmed

The fine structure of melanogenesis in coat color mutants of the mouse.

TYR HPS6

7.79e-04916424634048
Pubmed

Matrix metalloproteinases regulate morphogenesis, migration and remodeling of epithelium, tongue skeletal muscle and cartilage in the mandibular arch.

MMP3 MMP11

7.79e-04916429108368
Pubmed

FGF8 and BMP2 mediated dynamic regulation of dental mesenchyme proliferation and differentiation via Lhx8/Suv39h1 complex.

CERT1 BMP7 FGFR2

8.31e-0439164333580754
Pubmed

A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

CH25H CDH23 IDE WDFY4 HPS6 ITPRIP FGFR2 CFAP46

8.33e-04415164816385451
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

POLE HJURP CHD8 MAST2 FAM120A EML5

8.47e-04232164625515538
Pubmed

A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.

POLE CCDC115 GLP2R TYR RPAP1 CLEC11A ANAPC4 GABPB1

8.86e-04419164828700943
Pubmed

Massively parallel DNA sequencing facilitates diagnosis of patients with Usher syndrome type 1.

CDH23 USH2A

9.70e-0410164224618850
Pubmed

The testis-specific factor CTCFL cooperates with the protein methyltransferase PRMT7 in H19 imprinting control region methylation.

PRMT7 DNMT3B

9.70e-0410164217048991
Pubmed

Usher protein functions in hair cells and photoreceptors.

CDH23 USH2A

9.70e-0410164224239741
Pubmed

Localization of non-Mhc collagen-induced arthritis susceptibility loci in DBA/1j mice.

DPP4 PTGS1

9.70e-0410164210051620
Pubmed

Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.

TRPM6 PRMT7

9.70e-0410164220700443
Pubmed

Calmodulin interacts with the cytoplasmic tails of the parathyroid hormone 1 receptor and a sub-set of class b G-protein coupled receptors.

GLP2R SCTR

9.70e-0410164215670850
Pubmed

ATG4B contains a C-terminal LIR motif important for binding and efficient cleavage of mammalian orthologs of yeast Atg8.

ATG4C ATG4D

9.70e-0410164228287329
Pubmed

Strain background effects and genetic modifiers of hearing in mice.

MAP1A CDH23

1.18e-0311164216579977
Pubmed

Whole exome sequencing identifies novel recurrently mutated genes in patients with splenic marginal zone lymphoma.

FAT4 USH2A

1.18e-0311164224349473
Pubmed

Progression of calvarial bone development requires Foxc1 regulation of Msx2 and Alx4.

BMP7 FGFR2

1.18e-0311164214512019
Pubmed

Loss of nidogen-1 and -2 results in syndactyly and changes in limb development.

HSPG2 BMP7

1.18e-0311164217023412
Cytoband16p11.2

DOC2A SPNS1 NPIPB11 FBXL19 ITGAL TAOK2 PHKG2 RUSF1

4.86e-07191164816p11.2
Cytoband16q23.1

DUXB LDHD ZNRF1 TMEM231

5.22e-0632164416q23.1
CytobandEnsembl 112 genes in cytogenetic band chr16p11

DOC2A SPNS1 NPIPB11 FBXL19 ITGAL TAOK2 PHKG2 RUSF1

7.90e-062781648chr16p11
CytobandEnsembl 112 genes in cytogenetic band chr16q23

CHST5 DUXB LDHD ZNRF1 TMEM231

6.37e-051161645chr16q23
Cytoband12q13-q14

MYO1A RDH5

1.88e-046164212q13-q14
GeneFamilyGlucagon receptor family

GLP2R SCTR

4.30e-046982269
GeneFamilyAutophagy related

ATG4C ATG9A ATG4D

7.49e-04339831022
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6 MMP11

5.65e-071911648989bf108c7f2c78dd7f14481570f1819673a5469
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6 MMP11

5.65e-0719116483e7fbe4af2c23b3b964becde843d2f088ad41c23
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6 MMP11

5.65e-071911648bc2f3c4e71e3a55fe76ea03f45746329a8fc81da
ToppCellBAL-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6 MMP11

5.88e-071921648d9ff2293358c8b031ba212021012e058014ff472
ToppCellSevere_COVID-19-Myeloid-pDC|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6 MMP11

5.88e-071921648f79424c643a375dfe4579eff7ac1ba191e28a283
ToppCellBAL-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6 MMP11

5.88e-0719216482e8611d65090e39f1a6e74c972288e7b68376d15
ToppCellBAL-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6 MMP11

5.88e-07192164843569726df281eebe57499e0993b9fd9d36118c2
ToppCelldistal-3-Hematologic-Plasmacytoid_Dendritic|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CUX2 MAP1A TMEM8B CDH23 ARHGAP9 TLR9 WDFY4 PHEX

6.87e-0719616486028b790abba9bad1d5373bab13eb24855988f48
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CUX2 MAP1A TMEM8B CDH23 ARHGAP9 TLR9 WDFY4 PHEX

7.14e-0719716483a5908deb5c5a2bf06019a102fb1652233cf2a2a
ToppCellfacs-Large_Intestine-Distal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGS1 AWAT1 TMEM121 TYR SCTR ADGRF3 CFAP46

1.63e-0615316473b1b0cc8e9dd2b1484649789330713282ee44414
ToppCell368C-Myeloid-Dendritic-pDC|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

DPP4 LMF1 MAP1A POLE VARS2 MYO15B RPAP1

3.41e-061711647f3bf5805823d5733b58742172e7668725ce82931
ToppCell368C-Myeloid-Dendritic-pDC|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

DPP4 LMF1 MAP1A TMEM8B POLE MYO15B RPAP1

3.41e-061711647714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCellwk_08-11-Mesenchymal-Mesothelial-Late_mesothelial|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NPR1 ZBTB7C NPIPB11 CDCP1 PTGS1 GLP2R SCTR

5.15e-061821647f8257c884393f168f605d371e0840cfca8d3657e
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

5.73e-061851647f4588468e8654363f48adbe427dff10f16f1c7fe
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

5.73e-0618516473cb816fc9541c04b4436e21d984216cfbbacff98
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

5.73e-061851647c2e70405969616c28fb6379ee318e17bbcef7b49
ToppCellMild-Lymphoid-pDC|Mild / Condition, Lineage, Cell class and cell subclass

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

5.93e-0618616477fa82972c726025d6402e5eb7bf0db3b699eba4c
ToppCellBAL-Mild-Myeloid-pDC-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

5.93e-061861647b031f4e6867b6200b85f43276a34749bf5f4603f
ToppCellBAL-Mild-Myeloid-pDC|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

5.93e-061861647d2fbf53aac905c9896272ec5c2db28ee1a60f4be
ToppCellMild-Lymphoid-pDC-|Mild / Condition, Lineage, Cell class and cell subclass

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

5.93e-0618616471d05e73ae2ec0cc27f79e4fa40d6b21790059f80
ToppCellBAL-Mild-Myeloid-pDC-pDC-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

5.93e-06186164779aedd5aed72509a4925e9f6cb43bc0c798c86f5
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1|Hippocampus / BrainAtlas - Mouse McCarroll V32

RDH5 CDH23 ITGAL SLC4A1 NTNG2

6.05e-067016458d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCellMild_COVID-19-Myeloid-pDC|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11 C6orf141

6.15e-06187164799c3c4a7b9179dce7982dc6516d561c952abc80e
ToppCell3'_v3-bone_marrow-Myeloid_Dendritic-pDC|bone_marrow / Manually curated celltypes from each tissue

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX MMP11

6.82e-061901647dde0e34f6a06cdbbb65c86472360c09f0279a572
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 TESK2 LRP4 FGFR2 PLXNB3

6.82e-061901647ae97df1b06bcd46c05759b53c35dc8fea97f4ac1
ToppCellCOVID-19-Lymphoid-pDC|COVID-19 / Condition, Lineage and Cell class

HSPG2 CUX2 MAP1A TMEM8B TLR9 PHEX MMP11

7.06e-06191164725343b11d42128ad16659e5519cd1673266cc505
ToppCellLPS_only-Endothelial-Epi-like|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HJURP PTGS1 PIGQ LDHD WDR17 RSPH9

7.34e-0612616464c598f7bae09aca7a4ecce63dfd6890b26468c73
ToppCellLPS_only-Endothelial-Epi-like-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HJURP PTGS1 PIGQ LDHD WDR17 RSPH9

7.34e-061261646e065304f480a5e38532b66508b0ee87cc48bba9b
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CUX2 MAP1A TMEM8B CDH23 WDFY4 PHEX MMP11

7.81e-0619416475250736b608001fb73aa74dee8cb8465a1d2f372
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CCNL2 RDH5 RYR3 CRYAB PKD1 TENM1 C6orf141

8.35e-061961647b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCellTracheal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-T_reg|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

TRPM6 DPP4 HJURP ITGAL NTNG2 CD6 ADGRF3

8.35e-0619616476362fb0b5dc923f19a76b605d7289a16f89220e3
ToppCellLPS-antiTNF-Lymphocytic_NKT-T_cells-iNKT-MAIT|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DPP4 PDE4A ARHGAP9 PITPNM1 CD6 CFAP46

1.34e-051401646a8f3b01d03ee0bf0e752327a98d6b9035930c2b0
ToppCellControl-Lymphocytic_NKT-T_cells-iNKT-MAIT|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE4A SLC5A7 DHRS13 ARHGAP9 ITGAL WDR17

2.06e-0515116467e5e35ce601ca3d3722063566e89664909171b8d
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CUX2 MAP1A TLR9 WDFY4 PHEX PRMT7

2.85e-05160164661f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

CUX2 MAP1A TLR9 WDFY4 PHEX PRMT7

2.85e-05160164634b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 EFNA1 EML5 SCTR FGFR2 C6orf141

3.06e-0516216462259e9536147e9cdee772e3a30ba7d104573262c
ToppCellInfluenza_Severe-pDC|World / Disease group and Cell class

CUX2 MAP1A PHEX ABCA6 PRMT7 MMP11

3.51e-051661646bd25ce4c03c3d6cd9d986b9be1d355da52f0f2d7
ToppCellInfluenza_Severe-pDC|Influenza_Severe / Disease group and Cell class

CUX2 MAP1A PHEX ABCA6 PRMT7 MMP11

3.51e-051661646b43a5cd4d28118cf6e56a435deb8ea9435608a90
ToppCell356C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

HSPG2 EFNA1 EML5 SCTR FGFR2 C6orf141

3.51e-05166164689e2b8453180983533faccb4275867861876d7ee
ToppCell10x5'-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11

3.75e-05168164690f713dae3fcbd6ca801a019e3861c263ff3366b
ToppCellmild_COVID-19_(asymptomatic)-pDC|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

DPP4 CUX2 MAP1A WDFY4 PHEX BMP7

3.75e-051681646968405ea56f7d001ef83ff9274610923c3b2d55d
ToppCell10x5'-blood-Myeloid_Dendritic-pDC|blood / Manually curated celltypes from each tissue

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX

4.01e-05170164659cb1262ff319349d42b11afbec2a9035b7b79f2
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SPNS1 NPIPB11 PGLYRP2 LDHD ABCA6 HPS6

4.42e-051731646ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

FAT4 WDFY4 CLEC11A LRP4 FGFR2 WDR24

4.56e-051741646430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-myeloid-myeloid_dendritic-plasmacytoid_dendritic_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CUX2 MAP1A CDH23 TLR9 WDFY4 PHEX

4.71e-05175164697fe431f224b592b3076632d101e19136c138dcc
ToppCellControl-Lymphoid-pDC|Control / Condition, Lineage and Cell class

DPP4 HSPG2 CUX2 MAP1A TLR9 PHEX

4.86e-0517616465de16ff65476bde8b23322a44e11412e14f1bafe
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM46 DPP4 TMEM121 TESMIN TMEM131 DNMT3B

4.86e-051761646d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCellrenal_papilla_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

HSPG2 ZBTB7C PTGS1 CRYAB ZFHX4 LRP4

5.51e-05180164649829e833fe6d2431cfd2e8f378c2aaa3b2b46a4
ToppCellSevere-Lymphoid-pDC|Severe / Condition, Lineage, Cell class and cell subclass

MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6

5.68e-0518116462caecb7c5dcdad46fd02b4ffb73cb613ce835187
ToppCell3'_v3-Lung-Myeloid_Dendritic-pDC|Lung / Manually curated celltypes from each tissue

CUX2 MAP1A TMEM8B TLR9 PHEX MMP11

5.68e-0518116463d7f089fb434fbc989f1fa159e22133ae00b2487
ToppCellSevere-Lymphoid-pDC-|Severe / Condition, Lineage, Cell class and cell subclass

MAP1A TMEM8B TLR9 WDFY4 PHEX ABCA6

5.68e-051811646277ce4c49121da0990a5933b19d2c6af9bbe253e
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Deuterosomal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

DOC2A PITPNM1 MRAP TMEM231 RSPH9 CFAP46

5.86e-051821646000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TRPM6 HSPG2 FAT4 ZBTB7C DHH MIGA1

6.04e-051831646351d575339038bd4a66f408da518c567444208e8
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DPP4 NPR1 ZBTB7C PTGS1 GLP2R SCTR

6.41e-051851646492529121cb9e88bd3c0db6b54af3cd2979572bc
ToppCellPBMC-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B WDFY4 PHEX MMP11

6.61e-05186164631df1eafa3010bc1be6fc4d4689f1393d69b6b13
ToppCellPBMC-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B WDFY4 PHEX MMP11

6.61e-051861646eaa431ccd4cdd36fe06a44987603ec9979025aa8
ToppCellPBMC-Severe-Myeloid-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CUX2 MAP1A TMEM8B WDFY4 PHEX MMP11

6.61e-051861646b95be984e308d4f9061274a35995ec558d434e74
ToppCellPBMC-Severe-Myeloid-pDC-pDC-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CUX2 MAP1A TMEM8B WDFY4 PHEX MMP11

6.61e-0518616468f7949740286f64e034d1eb533ebc2c6f71ae966
ToppCellPBMC-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

CUX2 MAP1A TMEM8B WDFY4 PHEX MMP11

6.61e-05186164695c7318e521fb6aa02e244b1e81e6b2a62107756
ToppCellPBMC-Severe-Myeloid-pDC-pDC|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CUX2 MAP1A TMEM8B WDFY4 PHEX MMP11

6.61e-051861646b70cd94c651b56dcf2e55554533a5f1130845390
ToppCellCOVID-19_Severe-Myeloid-pDC|COVID-19_Severe / Disease group, lineage and cell class

CUX2 MAP1A TMEM8B WDFY4 PHEX MMP11

6.61e-0518616463db5ed69d49e5d79f990aca0295ddce4c297a05c
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

HSPG2 ZBTB7C CH25H CRYAB CLEC11A MMP3

7.01e-051881646b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_mesothelial_(19)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DPP4 NPR1 CDCP1 PTGS1 GLP2R SCTR

7.01e-0518816469655a4c47b644a870017d349b99063e17dbae572
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

7.01e-051881646505b6b4277d7dea87aee27191d0acca67928b8e6
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Dendritic-plasmacytoid_dendritic_cell-Plasmacytoid_DCs-Plasmacytoid_DCs_L.1.5.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CUX2 MAP1A TMEM8B CDH23 WDFY4 PHEX

7.01e-0518816461f820cb19eb0e15f0eb69d07e457072bbdad8ecb
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Macroglial|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

7.22e-051891646784ace2be87f2ecb19490f4974f63a559516e0eb
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

7.22e-05189164642ab4cc5fbf8580841f31889446fe4499df1a464
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

7.22e-05189164637ecbd73408d462b47d7e5611f203143e08a2689
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A PITPNM1 TESMIN TMEM231 RSPH9 CFAP46

7.43e-0519016460adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

7.43e-0519016462de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCellmyeloid-pDC|World / Lineage and Cell class

CUX2 MAP1A TMEM8B CDH23 WDFY4 PHEX

7.43e-05190164688c42779ce2f817d28e672d83f3f1158581edf73
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

7.43e-05190164607f21386ea6eb23416a537d2250e3042efe93fb0
ToppCellCOVID-19_Severe-pDC|COVID-19_Severe / disease group, cell group and cell class

CUX2 MAP1A TMEM8B WDFY4 PHEX MMP11

7.43e-051901646c5ab6b7492fb86aff3d2af3eb671c9f985ae4aeb
ToppCell3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MAP1A PITPNM1 TESMIN TMEM231 RSPH9 CFAP46

7.43e-05190164605455775845f4ded5c27e7b83242078d23162aaf
ToppCell(01)_Dendritic_cell|World / immune cells in Peripheral Blood (logTPM normalization)

CUX2 MAP1A TMEM8B WDFY4 PHEX MRAP

7.65e-0519116461f4c8078e1a6cd14937c714330af608caced2acf
ToppCellCOVID-19_Moderate-pDC|COVID-19_Moderate / disease group, cell group and cell class

CUX2 MAP1A TMEM8B CDH23 WDFY4 PHEX

7.65e-0519116469d0ffa65c547e20b4076fd97776d7738cbd453ec
ToppCell10x3'2.3-week_17-19-Myeloid_DC-DC-pDC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

CUX2 MAP1A TMEM8B CDH23 PHEX ABCA6

7.65e-051911646faf4de97003a938a243b0101456913c2b0e1804f
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MYO15B ZFHX4 TESK2 LRP4 FGFR2 PLXNB3

7.65e-0519116462b056cbe2e82e056e1f798974999378460eb1d16
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

7.65e-051911646f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

7.65e-051911646a90c8ab2077e52bbc998457c85a1b9867f9c8c93
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

PTGS1 PRDX6 TENT5B CRYAB EFNA1 MMP11

7.87e-051921646be5e246b2350398b985767b2fbede17a8dd8cc44
ToppCellVE-pDC-|VE / Condition, Cell_class and T cell subcluster

CUX2 MAP1A TMEM8B CDH23 WDFY4 PHEX

8.10e-051931646583724de588fcde3aeda056138c522dc0225a387
ToppCellVE-pDC|VE / Condition, Cell_class and T cell subcluster

CUX2 MAP1A TMEM8B CDH23 WDFY4 PHEX

8.10e-051931646bb759dc9ef0ec41d655002f59021d62d62d44289
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_endothelial_cells|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 RALGAPA2 PTGS1 TAOK2 EFNA1 MRAP

8.33e-051941646c5e77650d7abee339ec38fa78a622bb124db3fa5
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC3|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CUX2 MAP1A TMEM8B CDH23 WDFY4 PHEX

8.33e-0519416463f9e4a8e5699bc379e8a0d337e0daef09632e71c
ToppCellPND07-28-samps-Mesenchymal-Matrix_fibroblast-mesenchymal_C|PND07-28-samps / Age Group, Lineage, Cell class and subclass

AWAT1 SLC4A1 EML5 SLC5A6 CACNG5

8.56e-051211645176de42c088988fe1a7838f96add26ee8a30e543
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPP4 RALGAPA2 PTGS1 TAOK2 EFNA1 MRAP

8.57e-051951646df644b4c3ddccd34614ece5a2378000e6bc0fa10
ToppCellBronchial-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX

8.57e-051951646fbc324c3435f32b9ca269d83333faecfe940d7fe
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CUX2 FAM180B MAP1A TLR9 WDFY4 PHEX

8.82e-051961646170629b9ae82e9a911b93e8739dcd38176fbecb4
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

HSPG2 PTGS1 PRDX6 CRYAB EFNA1 MMP11

8.82e-051961646484bbc6b1f58bc260964babb949d14f5df101393
ToppCell3'-GW_trimst-1.5-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CH25H RYR3 LRP4 MMP3 MMP11 GPR151

8.82e-0519616461bcae4e0a244af822e2b12b2026a2771316f107d
ToppCellInfluenza-Influenza_Severe-Myeloid-pDC|Influenza_Severe / Disease, condition lineage and cell class

DPP4 MAP1A PHEX ABCA6 PRMT7 MMP11

9.06e-051971646e8e6f71e6dc8a695e4321a18543c1df63dd62f3e
ToppCell3'-GW_trimst-1-SmallIntestine-Mesenchymal-fibroblastic-Stromal_2_(CH25H+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CH25H RYR3 BMP7 CLEC11A LRP4 MMP11

9.06e-051971646467e7cbf511d3bcc701923603032aaf0bba2736d
ToppCelldistal-Hematologic-Plasmacytoid_Dendritic|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CUX2 MAP1A TMEM8B TLR9 WDFY4 PHEX

9.32e-051981646bb03744d8372405c278a0781e2f513bed00cf2b3
ToppCellControl_saline-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|Control_saline / Treatment groups by lineage, cell group, cell type

RYR3 PHEX BMP7 EML5 CLEC11A LRP4

9.32e-0519816460c4d2c68a42f8a9e964e2dd28092fe75f5216834
ToppCelldistal-2-Hematologic-Plasmacytoid_Dendritic|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CUX2 MAP1A TLR9 WDFY4 PHEX MMP11

9.58e-05199164678796b05d28b35e7361b6271d4a3858faa39c45c
ToppCellTransverse-T_cell-Tfh|T_cell / Region, Cell class and subclass

COQ6 CH25H FBXL19 QSOX1 ABCA6 TESK2

9.58e-05199164633ffea12b8228e0b5bd8942531c3b21d24224725
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRIM46 TRPM6 DHRS13 CDCP1 SLC5A6

9.61e-051241645d88bce8a4f023d5b617b2e8e372a94bd1248d20d
ToppCellMacroglial|World / cells hierarchy compared to all cells using T-Statistic

BMP7 MYO15B ZFHX4 LRP4 FGFR2 PLXNB3

9.85e-052001646e6935ad49216d2500c15c05cbc2b89402c65e838
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell|GW12 / Sample Type, Dataset, Time_group, and Cell type.

MYO15B NOP14 EML5 HPS6 CHPF2 TMEM231

9.85e-0520016466b7314c425f6b40f1301dd39cc02b0436e96a2ec
DrugU0125; Up 200; 1uM; PC3; HG-U133A

DPP4 MBTPS1 IFFO1 JMJD4 DELE1 CRYAB PHKG2 CLEC11A CHPF2 PRMT7

1.40e-0619616110663_UP
Diseasemagnesium measurement

TRIM46 TRPM6 FGFR2 PRMT7

4.62e-04661604EFO_0004845
Diseasestromal cell-derived factor 1 measurement

DPP4 ABCA6

6.03e-0471602EFO_0020756
DiseaseIntellectual Disability

CUX2 SRD5A3 ASH1L CHD8 CERT1 NTNG2 SLC5A6 RNASEH2C FGFR2

7.81e-044471609C3714756
Diseaseviral load

MKRN3 TRPM6 CUX2 ZBTB7C LRP4

8.95e-041361605EFO_0010125
DiseaseOdontome

LRP4 FGFR2

1.28e-03101602C0524730
Disease3-methyl-2-oxobutyrate measurement

FAT4 ANKRD50

1.28e-03101602EFO_0021020
DiseaseTooth Abnormalities

LRP4 FGFR2

1.28e-03101602C0040427
DiseaseColorectal Carcinoma

MKRN3 POLE TLR9 GDAP1L1 RPAP1 ABCA6 TOMM40L TENM1 MMP11 ANAPC4 GABPB1

1.62e-0370216011C0009402
DiseaseCraniofacial Abnormalities

HSPG2 MBTPS1 PHEX FGFR2 DNMT3B

1.65e-031561605C0376634
Diseasesmall vessel stroke

FAT4 C6orf89 ANKRD50 RALGAPA2

1.88e-03961604EFO_1001504
Diseaseintercellular adhesion molecule 5 measurement

PDE4A ABCA6

2.19e-03131602EFO_0008164
Diseasecalcium measurement

TRIM46 TRPM6 MAP1A CHD8 TMEM121 SLC4A1 ABCA6 USP40 MIGA1 TMEM131

2.34e-0362816010EFO_0004838
Diseasecholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement

LMF1 CERT1 TOMM40L LRP4

2.43e-031031604EFO_0008595, EFO_0020944
Diseaseatrial fibrillation (is_implicated_in)

AGXT2 MMP3

2.55e-03141602DOID:0060224 (is_implicated_in)
Diseasebeta-amyloid 1-42 measurement, cerebrospinal fluid biomarker measurement

FAT4 ANKRD50

2.55e-03141602EFO_0004670, EFO_0006794
Diseaseblood phosphate measurement

TRIM46 HSPG2 CUX2 USP40 TMEM131

2.65e-031741605EFO_0010972
DiseaseSchizophrenia

PDE4A IDE PTGS1 PRDX6 PITPNM1 TYR NTNG2 EML5 CACNG5 FGFR2 MMP3 DNMT3B

3.25e-0388316012C0036341
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

SLC5A7 LRP4

3.34e-03161602C0751885
DiseaseAlzheimer's disease (implicated_via_orthology)

IDE PTGS1 TOMM40L

3.69e-03571603DOID:10652 (implicated_via_orthology)
DiseaseBenign neoplasm of stomach

POLE FGFR2

3.77e-03171602C0153943
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

SLC5A7 LRP4

3.77e-03171602C0751883
DiseaseNeoplasm of uncertain or unknown behavior of stomach

POLE FGFR2

3.77e-03171602C0496905
Diseaseglycochenodeoxycholate measurement

NTNG2 MED27

3.77e-03171602EFO_0010490
DiseaseCarcinoma in situ of stomach

POLE FGFR2

3.77e-03171602C0154060
Diseaseintelligence, self reported educational attainment

DPP4 EFNA1 HPS6 MED27

3.84e-031171604EFO_0004337, EFO_0004784
DiseasePolydactyly

EBP LRP4 FGFR2 TMEM231

3.84e-031171604C0152427
DiseaseMalignant neoplasm of endometrium

POLE FGFR2

4.22e-03181602C0007103
DiseaseCarcinoma in situ of endometrium

POLE FGFR2

4.22e-03181602C0346191
Diseaseserum gamma-glutamyl transferase measurement

TRIM46 CUX2 ZBTB7C MAP1A FAM53A ASH1L FBXL19 NTNG2 EFNA1 PKD1 FGFR2 DNMT3B

4.28e-0391416012EFO_0004532
Diseasegout

TRIM46 CUX2 NTNG2 FGFR2 MED27

4.40e-031961605EFO_0004274
DiseaseCongenital Myasthenic Syndromes, Presynaptic

SLC5A7 LRP4

4.70e-03191602C0751884
Diseasesquamous cell carcinoma (is_marker_for)

TLR9 FGFR2

4.70e-03191602DOID:1749 (is_marker_for)
DiseaseCCL2 measurement

CDCP1 SLC4A1 EFNA1 KCNQ4

4.99e-031261604EFO_0004749

Protein segments in the cluster

PeptideGeneStartEntry
LGRLWHTSTVFFHPP

AGXT2

131

Q9BYV1
EATNLSWFLRHPGSP

ADGRF3

261

Q8IZF5
WVHREPSESSPLALG

ASH1L

1556

Q9NR48
HLFWPPGSALTARLR

CHD8

1736

Q9HCK8
DPLNWFGILVPHSLR

CCDC115

121

Q96NT0
LHRLASFHRVWSFPP

ANAPC4

46

Q9UJX5
GRSWSVPVIRHLFAP

DNMT3B

831

Q9UBC3
RGWVIHPLGLRSEFP

SLC4A1

646

P02730
PVPWLSEFRGRANLH

B4GALNT3

111

Q6L9W6
LHLPWFHPRNVSGFS

CDCP1

196

Q9H5V8
DRATGRPWLPLHTLS

FAT4

6

Q6V0I7
RIESSPFPLSHIGLW

ABCA6

996

Q8N139
PTFWILFLHLSGDRS

CFAP46

2166

Q8IYW2
AVRAAPHSGPLVSWR

COQ6

11

Q9Y2Z9
DLFGPITLHSPSDWI

AMZ2

46

Q86W34
LWPSSPASLQRGLHR

ANKRD50

91

Q9ULJ7
AAAPVGRFTAHWRVP

NPR1

121

P16066
LPTRPHWFLLFGTTE

CCNL1

261

Q9UK58
FDPSGQPRRDLHTSW

CUX2

121

O14529
LRAAAPHSFVALWAP

BMP7

6

P18075
PHSFVALWAPLFLLR

BMP7

11

P18075
PRVWTFLAHDRDSGP

CDH23

1761

Q9H251
ISWFGDSPLALFGLH

ATG4C

201

Q96DT6
ALAHSLGRWLVYPGS

ABHD16B

101

Q9H3Z7
LAAGSDHPLPRAAWL

FBXL19

416

Q6PCT2
AAAWGPELPSHRTVL

HJURP

96

Q8NCD3
LAHGTPPLTFQWSRV

HSPG2

3321

P98160
SEPHFRGFPCSLWVL

QSOX1

396

O00391
PPSFLRAPSWFDTGL

CRYAB

51

P02511
GTPLNHFRRIIWCPF

EDC4

226

Q6P2E9
RFHPELWCSGRSVPL

ITPRIP

221

Q8IWB1
AASPAHWPRESLVLY

GDAP1L1

36

Q96MZ0
RRSLSPATWDCFHPG

PCDHGB6

716

Q9Y5F9
HSWASRLFAPNVLPG

CDRT15

171

Q96T59
RLHWPTSLPSGDAFS

CERT1

346

Q9Y5P4
WAVQALPGLHFTPGR

CD6

206

P30203
SFHSAWLTVLPAPGR

FGFR2

351

P21802
LSISGWFHGPSLTRP

OGFOD1

231

Q8N543
PLREHATRSPWASDF

MAP1A

1741

P78559
GDWRDPSPRLVLHFG

NEIL2

156

Q969S2
PLRRASLSLGSGFWH

MBTPS1

161

Q14703
WKAQHPLLRSLFPEG

MYO1A

536

Q9UBC5
HSFQSRLPLPEPWRG

MYG1

311

Q9HB07
PFTTDWLGTSPLHLA

GABPB1

31

Q06547
LHLISSFWPSLPSGV

MMP3

326

P08254
PHTWLGRVLAAGFAL

KCNQ4

291

P56696
FRGLPASFHCWLELP

PLXNB3

711

Q9ULL4
NHYRFSLSWPRLLPT

LCTL

106

Q6UWM7
LPAWRTLSVSEHAPG

PDE4A

821

P27815
PGDALFDLLRTWPHF

PGLYRP2

531

Q96PD5
PVDSTLGFLPWHIRL

NUS1

246

Q96E22
WPAPLFGLLFLLSSH

MBOAT7

196

Q96N66
TGWVGRFRPSEPHFT

DPP4

351

P27487
FYRWLRSPSSLLHDP

POLE

1821

Q07864
PDEDLASFHWSLLGP

FAM120A

246

Q9NZB2
GLPPTWRDFRTLEAF

MED27

291

Q6P2C8
WLRNSLRPSPSFTHF

PTGS1

76

P23219
ITGLLFPTSDFWHPV

NOP14

551

P78316
APNGRNPSFLISSWH

RALGAPA2

1486

Q2PPJ7
SLLPLPEWFFSTIRH

GPR151

166

Q8TDV0
VILFTLLAGSPPFWH

PHKG2

221

P15735
LLAGSPPFWHRRQIL

PHKG2

226

P15735
HGAWRLPVSIPLFGR

PRR7

256

Q8TB68
IWSFSHARRLGPGLE

IFFO1

196

Q0D2I5
GGSPWLHIIIAFPTS

NPIPB11

56

E5RHQ5
RGLEAPPRGWSVSLH

MYO15B

681

Q96JP2
QSLFLGAPFPSWLHG

SRD5A3

96

Q9H8P0
GAPFPSWLHGLLRIL

SRD5A3

101

Q9H8P0
FLHPDAWVRGRSPSD

CACNG5

231

Q9UF02
PLSFHRKCSLWAPGR

GLP2R

36

O95838
PVLFVVPWGFARAHL

GLP2R

311

O95838
LPEPTFWHGSVSIFR

KLHL21

546

Q9UJP4
ERWHTLTSELPPAAG

DOC2A

381

Q14183
FLLHPERWLGTRGDP

C6orf141

91

Q5SZD1
HSAAPRLFPLAWTVL

EFNA1

181

P20827
LGEPFFTTSLLPWHN

PRMT7

476

Q9NVM4
LLTPWHLVFAARGPA

DHH

266

O43323
LPNRPHWFLLFGATE

CCNL2

256

Q96S94
LDTLAAPYLAGHWPR

FAM117B

221

Q6P1L5
RVPSHFSRLPLGGWA

ATG9A

796

Q7Z3C6
RWVTPAGRPDFDHLL

JMJD4

116

Q9H9V9
HLRDSGLWFPVDPGA

LDHD

146

Q86WU2
TFPGITPHLATLSWF

AWAT1

126

Q58HT5
SLPHLAGREGWAFLP

C2CD4D

81

B7Z1M9
RPDATVGWHPINLFL

DUXB

176

A0A1W2PPF3
QHPFFTGLDWTGLLR

MAST2

781

Q6P0Q8
AWLLHPALPSTFRSV

IDE

6

P14735
PIWGLATHPSRDFFL

EML5

1696

Q05BV3
APEPVLSGAHTWRSL

C6orf89

86

Q6UWU4
FVPNDRPTWHILAGL

EBP

21

Q15125
HTWAPTPQGLLLLDF

HPS6

271

Q86YV9
HPGFLTAWPADRTAD

B3GNT8

351

Q7Z7M8
IPGLGRHSSTFVPWE

DENND1B

716

Q6P3S1
FSWPGTHRATPAFLV

IZUMO4

191

Q1ZYL8
GHRPAFPNSSWLPFH

PRSS51

26

A0A1B0GVH4
PPSRETVGHLWFVLF

PRSS51

191

A0A1B0GVH4
VLARPGSSLFSWHPV

CYB561D2

36

O14569
HLRSWEALLQSPFFP

CH25H

26

O95992
NSELFLRHVPGWLRP

DHRS13

231

Q6UX07
HSPLDRFFSSPLWHP

DELE1

121

Q14154
AFHIAAPLPVTATRW

PKD1

291

P98161
FFATSDSQPPRLHWL

SLC8B1

406

Q6J4K2
DSQPPRLHWLFAFLG

SLC8B1

411

Q6J4K2
AHRSPAVLPLGAWVL

TESMIN

131

Q9Y4I5
PPLSTWDFEHLLLTG

FAM180B

111

Q6P0A1
HISPVLAWGFLGPRN

MIGA1

536

Q8NAN2
RSWRAGSYLPLPHGS

NTNG2

326

Q96CW9
LASRHWQGLPSPVDA

MMP11

331

P24347
PFTTDWLGTSPLHLA

GABPB2

31

Q8TAK5
FWPAPSLSLGVPLHR

RUSF1

321

Q96GQ5
FVGLWISVPFALSHP

SLC5A7

196

Q9GZV3
LASFRPPFWGLRHSR

VARS2

6

Q5ST30
HVRWEAPFRPNGLLT

USH2A

2346

O75445
PPAPVLHFFLDSRWG

TRIM46

526

Q7Z4K8
IFPHWFPFSRALSGA

TCAIM

16

Q8N3R3
SLLWPGLTFYHAPRT

RSPH9

241

Q9H1X1
LDPDPFVRHTFWTLA

SLC5A6

246

Q9Y289
DSWGILFSHPRDFTP

PRDX6

31

P30041
LESLGAVFPHEPWLR

PIGQ

81

Q9BRB3
QSAHPAPTRGALTFW

PRR34

46

Q9NV39
LVSNSWAHAIFLPRP

PRR34

116

Q9NV39
LPLGGFQTHPTLLWE

MRAP

131

Q8TCY5
PFVASSAALRHWPFG

SSTR4

101

P31391
LARASQGLASHLPPW

TAOK2

1161

Q9UL54
TIPPGLFWRFQITIH

TENM1

411

Q9UKZ4
SHRGPLFIWTISGPD

WDR17

146

Q8IZU2
LFLSSPAWLPLHGVE

SKIV2L

61

Q15477
WVQLDLHFPPGLSFR

ITGAL

816

P20701
HPRTRYSPGWDAKLL

RDH5

276

Q92781
LSAFPGRHLSGLSWP

TENT5B

41

Q96A09
LVLPRGPDHFSWASP

CHST5

396

Q9GZS9
GQRVSFFAWHRSPRP

CLEC11A

256

Q9Y240
PAPFTPHSRFEVLGW

CHPF2

361

Q9P2E5
VSWFADHPRAPFGLH

ATG4D

216

Q86TL0
SWGFVHPRLLSVPEL

RETREG3

126

Q86VR2
GSHIPGWFRALLPKA

PITPNM1

66

O00562
DTSLQPIHPWFLLLG

WFDC5

181

Q8TCV5
PDPTFRGLWSAFHVE

ZFHX4

356

Q86UP3
VLRWGDPPFHTAGRL

TRPM6

926

Q9BX84
AARRHPWPTNVLLYG

MPV17L

11

Q2QL34
SALPHAARGWAPFPV

MKRN3

46

Q13064
SVLLWPHQPSGQRSF

TLR9

991

Q9NR96
PFLTAEPTHLRVGWA

RYR3

671

Q15413
GSSFIPGEHFWLLLL

SPNS1

141

Q9H2V7
PRSGLPLWAEGLTFF

TMEM121

171

Q9BTD3
WHLREFPLHPVASFS

SCTR

406

P47872
IGRRSSDPWSNSHFP

TMEM131

1866

Q92545
AHEAPAFLPWHRLFL

TYR

201

P14679
PWADGDPRKFISLHR

WDFY4

2726

Q6ZS81
FSRFTLWGLETIPGP

RNASEH2C

126

Q8TDP1
RFLDAHGAWLPELPS

UAP1L1

441

Q3KQV9
RHSPFRWPVLESNIG

PHEX

161

P78562
LLWTPGPKLFHGSLE

ARHGAP9

101

Q9BRR9
PFPQTGTWFLALRSL

TMEM8B

146

A6NDV4
RSQPEPLSSHSGLWR

TMEM114

56

B3SHH9
ALHLLPAAFSPFIWV

nan

126

A1L4Q6
AAPHLTPFSAWALRH

RPAP1

936

Q9BWH6
RPFWTFRVSHSPLLE

nan

136

Q8IYB0
PAWGPRAHRAYLTLL

UTS2R

201

Q9UKP6
NFLSATHLGGLFPPW

ZBTB7C

336

A1YPR0
IPPLLVAFRSHGFWL

TMEM231

36

Q9H6L2
PLPVTLALGAFLNHW

TOMM40L

281

Q969M1
TGIAWRHPHDPSFLL

WDR24

301

Q96S15
WFLALRQHGVPLSGP

TIGD5

131

Q53EQ6
RASWAFSHRFPSPLA

RNASEK

16

Q6P5S7
WLRVFSHSSPTGLPK

SMAD5-AS1

36

Q9Y6J3
IRRWRSLPGSPEFLH

TESK2

451

Q96S53
EPVTFAWQHRAPRGL

VSIG10L2

176

P0DP72
LEFGVPSPAHLRAWT

USP40

1011

Q9NVE5
PPWHLGVDSLFRRKA

UHRF1BP1

416

Q6BDS2
DALPLHIAPRWFSSH

ZNRF1

126

Q8ND25
LTAHWVSFESPARPR

ZBED4

746

O75132
RGLRTSPVHPNLWAS

FAM53A

341

Q6NSI3
LPQHTPTSRIVLWGF

LMF1

196

Q96S06
GSGRRIIADTHLFWP

LRP4

586

O75096