Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	beta-catenin binding	FOXO1 CDHR3 GRIN2B GSK3B MET SALL1 NUMB CDH13	5.67e-07	120	118	8	GO:0008013
GeneOntologyMolecularFunction	ionotropic glutamate receptor binding	GRIN2B GSK3B GNAS SDCBP	2.52e-04	52	118	4	GO:0035255
GeneOntologyMolecularFunction	chromatin binding	FOXO1 NCOA6 ARID1A CREBBP NCOA5 ARID1B SALL1 SATB1 SETSIP SUPT16H TAF2 NUP153 FOXC2	4.29e-04	739	118	13	GO:0003682
GeneOntologyMolecularFunction	transcription coactivator activity	NCOA6 ARID1A CREBBP ARID1B TADA1 MRTFB MAML2 NPAT	4.43e-04	303	118	8	GO:0003713
GeneOntologyMolecularFunction	transcription factor binding	FOXO1 MAGEA1 NCOA6 ARID1A CREBBP GSK3B SALL1 UBN1 SATB1 MTOR C1QBP VHLL USF2	5.12e-04	753	118	13	GO:0008134
GeneOntologyBiologicalProcess	regulation of cellular response to stress	FOXO1 TMEM67 UBQLN4 ARID1A CREBBP GSK3B MET ATF6 ARID1B TADA1 BRCA2 MTOR C1QBP VHLL TAF2 NPAS2	3.47e-07	598	119	16	GO:0080135
GeneOntologyBiologicalProcess	head development	EPHB2 TMEM67 NCOA6 AXL BCAN GRIN2B ARID1A CREBBP ARCN1 GSK3B MET MRTFB SALL1 BRCA2 PITX3 NUMB CRISPLD1 TRAPPC9	5.36e-06	919	119	18	GO:0060322
GeneOntologyBiologicalProcess	dendrite development	EPHB2 ITSN1 NLGN1 CUL7 CREBBP GSK3B MET ARID1B MTOR NUMB	2.48e-05	335	119	10	GO:0016358
GeneOntologyBiologicalProcess	adherens junction organization	CDHR3 NUMB PLEKHA7 CDH13 TBCD	2.70e-05	61	119	5	GO:0034332
GeneOntologyBiologicalProcess	response to nitrogen compound	EPHB2 FOXO1 TMEM67 GRIN2B BCAR1 CREBBP GSK3B RYR2 NCOA5 PHEX TGFBR3 ATF6 ARID1B DNAJC10 GLDC MTOR PITX3 GNAS CDH13 FOXC2	3.83e-05	1272	119	20	GO:1901698
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	FOXO1 NCOA6 CREBBP GSK3B MET ATF6 MRTFB SALL1 SETSIP PITX3 RNF10 MAML2 TAF2 USF2 MGA SLC38A3 CDH13 ZNF292 NPAS2 FOXC2 NPAT	4.28e-05	1390	119	21	GO:0045944
GeneOntologyBiologicalProcess	positive regulation of dendritic spine development	EPHB2 ITSN1 NLGN1 CREBBP MTOR	5.27e-05	70	119	5	GO:0060999
GeneOntologyBiologicalProcess	regulation of DNA repair	UBQLN4 ARID1A CREBBP ARID1B TADA1 C1QBP TAF2 NPAS2	6.47e-05	234	119	8	GO:0006282
GeneOntologyBiologicalProcess	regulation of cellular response to heat	CREBBP GSK3B MTOR	9.93e-05	16	119	3	GO:1900034
GeneOntologyBiologicalProcess	regulation of postsynapse organization	EPHB2 DOCK1 ITSN1 NLGN1 GRIN2B VHLL NUMB	1.00e-04	185	119	7	GO:0099175
GeneOntologyBiologicalProcess	brain development	EPHB2 NCOA6 AXL BCAN GRIN2B ARID1A ARCN1 GSK3B MET MRTFB SALL1 BRCA2 PITX3 NUMB TRAPPC9	1.27e-04	859	119	15	GO:0007420
GeneOntologyBiologicalProcess	dendritic spine development	EPHB2 ITSN1 NLGN1 CREBBP ARID1B MTOR	1.69e-04	141	119	6	GO:0060996
GeneOntologyBiologicalProcess	cellular response to hepatocyte growth factor stimulus	BCAR1 CREBBP GSK3B	1.70e-04	19	119	3	GO:0035729
GeneOntologyBiologicalProcess	regulation of dendritic spine development	EPHB2 ITSN1 NLGN1 CREBBP MTOR	1.84e-04	91	119	5	GO:0060998
GeneOntologyBiologicalProcess	regulation of organelle assembly	EPHB2 TMEM67 NLGN1 GSK3B MTOR RAB3GAP2 MPHOSPH9 SDCBP	2.23e-04	280	119	8	GO:1902115
GeneOntologyBiologicalProcess	response to hepatocyte growth factor	BCAR1 CREBBP GSK3B	2.31e-04	21	119	3	GO:0035728
GeneOntologyCellularComponent	clathrin-coated pit	ITSN1 CUBN AP2A1 STON2 NUMB	9.03e-05	80	118	5	GO:0005905
GeneOntologyCellularComponent	extrinsic component of plasma membrane	CDHR3 CUBN RYR2 RNF10 GNAS CDH13	1.28e-04	137	118	6	GO:0019897
GeneOntologyCellularComponent	chromatin	FOXO1 RHOXF2 NPAS3 ARID1A CREBBP ATF6 RHOXF2B ARID1B TADA1 SALL1 SATB1 SETSIP PITX3 SUPT16H TMPO TAF2 USF2 MGA NPAS2 FOXC2	2.23e-04	1480	118	20	GO:0000785
GeneOntologyCellularComponent	nuclear protein-containing complex	NCOA6 NUP210L TAF1C UBQLN4 CUL7 ARID1A CREBBP PCF11 ATF6 ARID1B SALL1 BRCA2 NUP210 SUPT16H AGFG1 TAF2 MGA NUP153 NPAS2	2.52e-04	1377	118	19	GO:0140513
GeneOntologyCellularComponent	Golgi-associated vesicle	CUBN ARCN1 SPPL2A AP2A1 GNAS	4.73e-04	114	118	5	GO:0005798
GeneOntologyCellularComponent	vesicle coat	SEC31B ARCN1 AP2A1 STON2	5.62e-04	67	118	4	GO:0030120
GeneOntologyCellularComponent	glutamatergic synapse	EPHB2 DOCK1 ITSN1 BCAN NLGN1 GRIN2B GSK3B AP2A1 MTOR RNF10 C1QBP VHLL NUMB	7.15e-04	817	118	13	GO:0098978
GeneOntologyCellularComponent	PML body	MAGEA1 CREBBP UBN1 SATB1 MTOR	7.20e-04	125	118	5	GO:0016605
GeneOntologyCellularComponent	synaptic cleft	CDHR3 NLGN1 GRIN2B	8.45e-04	33	118	3	GO:0043083
GeneOntologyCellularComponent	nuclear envelope	NUP210L ITSN1 RYR2 ATF6 MTOR NUP210 AGFG1 TMPO SDCBP NUP153	1.29e-03	560	118	10	GO:0005635
GeneOntologyCellularComponent	bBAF complex	ARID1A ARID1B	1.38e-03	10	118	2	GO:0140092
MousePheno	abnormal heart septum morphology	DOCK1 TMEM67 ARID1A CREBBP RYR2 TGFBR3 MRTFB GLDC TRAPPC9 DNAH11 FOXC2 NPAT	1.08e-05	388	94	12	MP:0006113
MousePheno	abnormal trophoblast layer morphology	NCOA6 CUL7 ARID1A VIRMA MET MTOR VHLL NUMB MGA	1.20e-05	211	94	9	MP:0005031
MousePheno	lethality throughout fetal growth and development	DOCK1 NCOA6 CUL7 VIRMA CREBBP GSK3B RYR2 TGFBR3 MET MRTFB BRCA2 CNOT4	3.36e-05	435	94	12	MP:0006208
MousePheno	ventricular septal defect	DOCK1 ARID1A CREBBP TGFBR3 MRTFB GLDC DNAH11 FOXC2 NPAT	6.41e-05	261	94	9	MP:0010402
MousePheno	abnormal vascular development	DOCK1 FOXO1 NCOA6 CUL7 CUBN ARID1A CREBBP TGFBR3 MRTFB VHLL NUMB FOXC2 NPAT	6.56e-05	542	94	13	MP:0000259
MousePheno	abnormal blood vessel morphology	DOCK1 FOXO1 TMEM67 NCOA6 NPAS3 CUL7 BCAR1 CUBN ARID1A CREBBP TGFBR3 MET ARID1B MRTFB RNF10 RNF38 VHLL NUMB TRAPPC9 CDH13 DNAH11 FOXC2 NPAT	8.54e-05	1472	94	23	MP:0001614
MousePheno	decreased body length	UBQLN4 PHEX ARID1B DNAJC10 PITX3 RNF10 CHSY3 GNAS UNC79 SLC38A3 CNOT4 DSE	9.38e-05	484	94	12	MP:0001258
MousePheno	abnormal interventricular septum morphology	DOCK1 ARID1A CREBBP RYR2 TGFBR3 MRTFB GLDC DNAH11 FOXC2 NPAT	9.84e-05	342	94	10	MP:0000281
MousePheno	abnormal social investigation	NPAS3 NLGN1 GRIN2B CREBBP ARID1B SUPT16H TRAPPC9	1.52e-04	171	94	7	MP:0001360
MousePheno	interrupted aortic arch	TMEM67 MRTFB DNAH11 FOXC2	1.60e-04	41	94	4	MP:0004157
MousePheno	abnormal pluripotent precursor cell morphology	ARID1A MRTFB MGA FOXC2	1.76e-04	42	94	4	MP:0002399
MousePheno	abnormal epicardium morphology	NCOA6 RYR2 TGFBR3	1.87e-04	17	94	3	MP:0003057
MousePheno	interrupted aorta	TMEM67 MRTFB DNAH11 FOXC2	1.94e-04	43	94	4	MP:0010544
MousePheno	embryonic lethality during organogenesis	FOXO1 NCOA6 BCAR1 CUBN ARID1A VIRMA CREBBP RYR2 MET SALL1 BRCA2 MTOR C1QBP VHLL NUMB FOXC2	2.24e-04	876	94	16	MP:0006207
MousePheno	lethality during fetal growth through weaning, complete penetrance	NCOA6 GRIN2B CUL7 ARID1A VIRMA CREBBP GSK3B RYR2 TGFBR3 MET HHIP ARID1B MRTFB SALL1 SATB1 GNAS UNC79 SLC38A3 CNOT4 FOXC2	2.45e-04	1269	94	20	MP:0011111
MousePheno	thin myocardium	NCOA6 BCAR1 TGFBR3 MRTFB FOXC2	2.65e-04	85	94	5	MP:0002652
MousePheno	abnormal substantia nigra size	PITX3 TRAPPC9	2.66e-04	4	94	2	MP:0020541
MousePheno	decreased substantia nigra size	PITX3 TRAPPC9	2.66e-04	4	94	2	MP:0020543
MousePheno	abnormal cardiovascular development	DOCK1 FOXO1 NCOA6 CUL7 BCAR1 CUBN ARID1A CREBBP RYR2 TGFBR3 MRTFB VHLL NUMB FOXC2 NPAT	2.80e-04	802	94	15	MP:0002925
MousePheno	abnormal body length	UBQLN4 PHEX ARID1B DNAJC10 PITX3 RNF10 CHSY3 GNAS UNC79 SLC38A3 CNOT4 DSE	3.07e-04	550	94	12	MP:0001256
MousePheno	abnormal extraembryonic tissue morphology	FOXO1 NCOA6 CUL7 CUBN ARID1A VIRMA CREBBP TGFBR3 MET MRTFB BRCA2 MTOR VHLL NUMB MGA CNOT4	3.35e-04	908	94	16	MP:0002086
MousePheno	lethality throughout fetal growth and development, complete penetrance	NCOA6 CUL7 VIRMA GSK3B TGFBR3 MET MRTFB CNOT4	3.89e-04	263	94	8	MP:0011099
MousePheno	abnormal myocardial trabeculae morphology	FOXO1 NCOA6 ARID1A RYR2 TGFBR3 DNAH11	4.16e-04	144	94	6	MP:0002189
MousePheno	xiphoid process foramen	CREBBP GSK3B	4.42e-04	5	94	2	MP:0004679
MousePheno	abnormal myocardium layer morphology	FOXO1 NCOA6 BCAR1 ARID1A CREBBP RYR2 TGFBR3 MRTFB DNAH11 FOXC2	4.58e-04	414	94	10	MP:0005329
MousePheno	abnormal heart and great artery attachment	DOCK1 TMEM67 TGFBR3 MRTFB GLDC DNAH11 NPAT	4.59e-04	205	94	7	MP:0010426
MousePheno	perinatal lethality	TMEM67 NCOA6 GRIN2B CUL7 ARID1A CREBBP GSK3B MET HHIP ARID1B MRTFB SALL1 PROKR2 BRCA2 GNAS UNC79 DNAH11 FOXC2	4.66e-04	1130	94	18	MP:0002081
MousePheno	abnormal vasculogenesis	DOCK1 FOXO1 CREBBP TGFBR3	4.69e-04	54	94	4	MP:0001622
MousePheno	abnormal heart and great vessel attachment	DOCK1 TMEM67 TGFBR3 MRTFB GLDC DNAH11 NPAT	5.00e-04	208	94	7	MP:0010425
MousePheno	double outlet right ventricle	DOCK1 TMEM67 MRTFB GLDC DNAH11 NPAT	5.17e-04	150	94	6	MP:0000284
MousePheno	abnormal heart layer morphology	FOXO1 NCOA6 BCAR1 ARID1A CREBBP RYR2 TGFBR3 MRTFB DNAH11 FOXC2	5.32e-04	422	94	10	MP:0010545
Domain	Big_2	NUP210L NUP210	3.82e-05	2	116	2	PF02368
Domain	Invasin/intimin_cell_adhesion	NUP210L NUP210	3.82e-05	2	116	2	IPR008964
Domain	BAF250/Osa	ARID1A ARID1B	3.82e-05	2	116	2	IPR021906
Domain	BAF250_C	ARID1A ARID1B	3.82e-05	2	116	2	IPR033388
Domain	BID_2	NUP210L NUP210	3.82e-05	2	116	2	SM00635
Domain	BAF250_C	ARID1A ARID1B	3.82e-05	2	116	2	PF12031
Domain	Big_2	NUP210L NUP210	3.82e-05	2	116	2	IPR003343
Domain	ARM-type_fold	DOCK1 CUL7 ARID1A VIRMA AP2A1 MTOR TAF2 UNC79 TBCD	2.67e-04	339	116	9	IPR016024
Domain	DUF1669	FAM83C FAM83B	1.04e-03	8	116	2	PF07894
Domain	DUF1669	FAM83C FAM83B	1.04e-03	8	116	2	IPR012461
Domain	Clathrin_mu	ARCN1 STON2	1.67e-03	10	116	2	IPR001392
Domain	Adap_comp_sub	ARCN1 STON2	2.03e-03	11	116	2	PF00928
Domain	-	CUL7 ARID1A ARID1B AP2A1 MTOR TBCD	2.64e-03	222	116	6	1.25.10.10
Domain	MHD	ARCN1 STON2	2.85e-03	13	116	2	PS51072
Domain	MHD	ARCN1 STON2	2.85e-03	13	116	2	IPR028565
Domain	-	ARID1A ARID1B	3.81e-03	15	116	2	1.10.150.60
Domain	BRIGHT	ARID1A ARID1B	3.81e-03	15	116	2	SM00501
Domain	ARID_dom	ARID1A ARID1B	3.81e-03	15	116	2	IPR001606
Domain	ARID	ARID1A ARID1B	3.81e-03	15	116	2	PS51011
Domain	ARID	ARID1A ARID1B	3.81e-03	15	116	2	PF01388
Domain	-	NPAS3 USF2 MGA NPAS2	4.76e-03	109	116	4	4.10.280.10
Domain	HLH	NPAS3 USF2 MGA NPAS2	5.08e-03	111	116	4	PF00010
Domain	HLH	NPAS3 USF2 MGA NPAS2	5.93e-03	116	116	4	SM00353
Domain	BHLH	NPAS3 USF2 MGA NPAS2	6.11e-03	117	116	4	PS50888
Pathway	REACTOME_NERVOUS_SYSTEM_DEVELOPMENT	EPHB2 DOCK1 DPYSL2 ITSN1 GSK3B MET AP2A1 NUMB SDCBP	2.01e-05	261	82	9	MM15676
Pathway	WP_NOTCH_SIGNALING_WP61	MAGEA1 GSK3B MTOR NUMB MAML2	2.71e-05	61	82	5	M39540
Pathway	WP_RUBINSTEINTAYBI_SYNDROME_1	FOXO1 CREBBP NPAS2	8.21e-05	15	82	3	M48323
Pathway	WP_MIRNA_REGULATION_OF_PROSTATE_CANCER_SIGNALING	FOXO1 CREBBP GSK3B MTOR	1.85e-04	49	82	4	M39683
Pathway	WP_VEGFAVEGFR2_SIGNALING	EPHB2 FOXO1 BCAR1 CREBBP GSK3B ATF6 AP2A1 MTOR NUMB SDCBP	1.92e-04	431	82	10	M39729
Pathway	REACTOME_EPH_EPHRIN_SIGNALING	EPHB2 ITSN1 GRIN2B AP2A1 SDCBP	1.95e-04	92	82	5	M27201
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	DOCK1 NCOA6 ITSN1 BCAR1 ZNF469 MRTFB SALL1 UBN1 STON2 AGFG1 RNF38 NUMB MAML2 MGA PLEKHA7 NUP153	2.17e-12	430	120	16	35044719
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	FOXO1 ITSN1 CUL7 BCAR1 ARID1A CREBBP GSK3B FAM83B MRTFB SALL1 UBN1 BRCA2 AGFG1 HELZ GNAS	2.04e-09	588	120	15	38580884
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	NCOA6 ZNF207 ARID1A CREBBP GSK3B NCOA5 PCF11 ARID1B DNAJC10 NUP210 TMPO HELZ NUP153	7.20e-09	457	120	13	32344865
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	FOXO1 NCOA6 RALGAPB BCAR1 VIRMA FAM83B MTOR RAB3GAP2 RNF10 AGFG1 NUMB HELZ MPHOSPH9 GNAS PLEKHA7 TRAPPC9 CNOT4	7.40e-09	861	120	17	36931259
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	CREBBP GSK3B SALL1 UBN1 AP2A1 BRCA2 SUPT16H ZNF518B MGA	8.47e-08	222	120	9	37071664
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RALGAPB CUL7 BCAR1 ARID1A GSK3B NCOA5 PCF11 ARID1B NUP210 SUPT16H C1QBP TMPO NUMB HELZ MPHOSPH9 PLEKHA7 NUP153	1.28e-07	1049	120	17	27880917
Pubmed	CRMP-2 regulates polarized Numb-mediated endocytosis for axon growth.	DPYSL2 AP2A1 NUMB	1.60e-07	4	120	3	12942088
Pubmed	Akt signalling through GSK-3beta, mTOR and Foxo1 is involved in human skeletal muscle hypertrophy and atrophy.	FOXO1 GSK3B MTOR	1.60e-07	4	120	3	16916907
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	NCOA6 ARID1A RYR2 ARID1B MRTFB NUP153 ZNF292	2.49e-07	123	120	7	26912792
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	NCOA5 UBN1 SATB1 SUPT16H C1QBP TMPO HELZ MGA SDCBP NUP153	3.98e-07	349	120	10	25665578
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	DPYSL2 TAF1C ITSN1 UBQLN4 DEF8 DNAAF9 GRIN2B ARID1A SEC31B CREBBP ARCN1 ATF6 SATB1 AP2A1 RNF10 RNF38 SDCBP ZNF292	4.50e-07	1285	120	18	35914814
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	RALGAPB CUL7 ARID1A FAM83B ARID1B AP2A1 C1QBP HELZ MPHOSPH9 PLEKHA7 TRAPPC9	4.52e-07	446	120	11	24255178
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	NCOA6 DPYSL2 ARID1A CREBBP ARCN1 ARID1B MRTFB RAB3GAP2 TMPO NUMB TAF2 MGA	4.78e-07	549	120	12	38280479
Pubmed	BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.	DOCK1 ITSN1 FAM83B DNAJC10 STON2 AGFG1 TMPO NUMB TRAPPC9	6.94e-07	285	120	9	34369648
Pubmed	Functional proteomics mapping of a human signaling pathway.	NCOA6 ITSN1 UBQLN4 CREBBP RYR2 ARID1B MRTFB AP2A1 POLI MGA SDCBP TBCD	1.03e-06	591	120	12	15231748
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	NCOA6 ZNF207 ARID1A PCF11 ARID1B SALL1 UBN1 BRCA2 SUPT16H AGFG1 C1QBP TMPO MGA NUP153 NPAT	1.09e-06	954	120	15	36373674
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXO1 RHOXF2 NPAS3 ZNF207 ARID1A CREBBP MET RHOXF2B SATB1 RNF10 USF2 ZNF292 FOXC2	1.12e-06	709	120	13	22988430
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	NCOA6 AXL ARID1A SEC31B VIRMA CREBBP RYR2 ARID1B SALL1 SERPINB1 TAF2 DNAH11	2.28e-06	638	120	12	31182584
Pubmed	Hepatocyte growth factor modulates interleukin-6 production in bone marrow derived macrophages: implications for inflammatory mediated diseases.	CREBBP GSK3B MET	3.31e-06	9	120	3	21072211
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	TAF1C ZNF207 UBN1 RAB3GAP2 RNF10 MAML2 TAF2 PLEKHH2 MGA TBCD DNAH11 FOXC2	4.99e-06	689	120	12	36543142
Pubmed	The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.	GRIN2B ARID1B TAF2 FOXC2	5.10e-06	33	120	4	19336002
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	DCDC1 POGK TAF1C CUL7 ARID1A CREBBP ZNF469 ARID1B TADA1 DNAJC10 SETSIP SUPT16H HELZ TAF2 MGA	7.31e-06	1116	120	15	31753913
Pubmed	A human MAP kinase interactome.	DOCK1 ITSN1 CREBBP ATF6 AGFG1 HELZ MPHOSPH9 USF2 MGA NUP153	7.63e-06	486	120	10	20936779
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	NCOA6 ARID1A ARID1B SATB1 ZNF292	1.05e-05	83	120	5	28794006
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	NCOA6 DPYSL2 BCAN GRIN2B BCAR1 TLR8 SATB1 AP2A1 BRCA2 MTOR GNAS	1.08e-05	621	120	11	22794259
Pubmed	Decidual PTEN expression is required for trophoblast invasion in the mouse.	FOXO1 GSK3B MTOR	1.12e-05	13	120	3	20858757
Pubmed	Targeting of CRMP-2 to the primary cilium is modulated by GSK-3β.	DPYSL2 GSK3B	1.18e-05	2	120	2	23185275
Pubmed	Glutamine transporter SLC38A3 promotes breast cancer metastasis via Gsk3β/β-catenin/EMT pathway.	GSK3B SLC38A3	1.18e-05	2	120	2	38309615
Pubmed	Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.	RHOXF2 RHOXF2B	1.18e-05	2	120	2	12087094
Pubmed	The Role of Receptor Tyrosine Kinases in Lassa Virus Cell Entry.	AXL MET	1.18e-05	2	120	2	32781509
Pubmed	Formation of molecular complexes by N-methyl-D-aspartate receptor subunit NR2B and ryanodine receptor 2 in neonatal rat myocard.	GRIN2B RYR2	1.18e-05	2	120	2	15010472
Pubmed	AXL and MET receptor tyrosine kinases are essential for lung cancer metastasis.	AXL MET	1.18e-05	2	120	2	28260071
Pubmed	Modulation of NMDA receptor-dependent calcium influx and gene expression through EphB receptors.	EPHB2 GRIN2B	1.18e-05	2	120	2	11799243
Pubmed	Role of the mTOR‑FOXO1 pathway in obesity‑associated renal tubulointerstitial inflammation.	FOXO1 MTOR	1.18e-05	2	120	2	30535458
Pubmed	Dissecting the role of SWI/SNF component ARID1B in steady-state hematopoiesis.	ARID1A ARID1B	1.18e-05	2	120	2	37611161
Pubmed	Subunits of ARID1 serve as novel biomarkers for the sensitivity to immune checkpoint inhibitors and prognosis of advanced non-small cell lung cancer.	ARID1A ARID1B	1.18e-05	2	120	2	32791957
Pubmed	Role of CBP and SATB-1 in aging, dietary restriction, and insulin-like signaling.	CREBBP SATB1	1.18e-05	2	120	2	19924292
Pubmed	aFGF Promotes Neurite Growth by Regulating GSK3β-CRMP2 Signaling Pathway in Cortical Neurons Damaged by Amyloid-β.	DPYSL2 GSK3B	1.18e-05	2	120	2	31561361
Pubmed	Potential role of FoxO1 and mTORC1 in the pathogenesis of Western diet-induced acne.	FOXO1 MTOR	1.18e-05	2	120	2	23614736
Pubmed	EphB receptors regulate dendritic spine development via intersectin, Cdc42 and N-WASP.	EPHB2 ITSN1	1.18e-05	2	120	2	12389031
Pubmed	Hepatic conditional knockout of ATF6 exacerbates liver metabolic damage by repressing autophage through MTOR pathway.	ATF6 MTOR	1.18e-05	2	120	2	30236984
Pubmed	HIV-1 Rev-binding protein accelerates cellular uptake of iron to drive Notch-induced T cell leukemogenesis in mice.	CREBBP AGFG1	1.18e-05	2	120	2	20516639
Pubmed	Chromatin accessibility underlies synthetic lethality of SWI/SNF subunits in ARID1A-mutant cancers.	ARID1A ARID1B	1.18e-05	2	120	2	28967863
Pubmed	Hirschsprung's disease: m6A methylase VIRMA suppresses cell migration and proliferation by regulating GSK3β.	VIRMA GSK3B	1.18e-05	2	120	2	38658662
Pubmed	DPYSL2/CRMP2 isoform B knockout in human iPSC-derived glutamatergic neurons confirms its role in mTOR signaling and neurodevelopmental disorders.	DPYSL2 MTOR	1.18e-05	2	120	2	37479784
Pubmed	Genetic variants in the FOXO1 and ZNF469 genes are associated with keratoconus in Sweden: a case-control study.	FOXO1 ZNF469	1.18e-05	2	120	2	38267912
Pubmed	Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.	RHOXF2 RHOXF2B	1.18e-05	2	120	2	16465597
Pubmed	Inhibition of glycogen synthase kinase-3 ameliorates β-amyloid pathology and restores lysosomal acidification and mammalian target of rapamycin activity in the Alzheimer disease mouse model: in vivo and in vitro studies.	GSK3B MTOR	1.18e-05	2	120	2	23155049
Pubmed	Cloning and characterization of the 5'-flanking region of the Ehox gene.	RHOXF2 RHOXF2B	1.18e-05	2	120	2	16414020
Pubmed	The increase of mTOR expression is consistent with FoxO1 decrease at gene level in acne but not in psoriasis.	FOXO1 MTOR	1.18e-05	2	120	2	31367853
Pubmed	Dual ARID1A/ARID1B loss leads to rapid carcinogenesis and disruptive redistribution of BAF complexes.	ARID1A ARID1B	1.18e-05	2	120	2	34386776
Pubmed	Convergence of the mammalian target of rapamycin complex 1- and glycogen synthase kinase 3-β-signaling pathways regulates the innate inflammatory response.	GSK3B MTOR	1.18e-05	2	120	2	21422248
Pubmed	Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma.	ARID1A ARID1B	1.18e-05	2	120	2	23202128
Pubmed	Role of the Akt/GSK-3β/CRMP-2 pathway in axon degeneration of dopaminergic neurons resulting from MPP+ toxicity.	DPYSL2 GSK3B	1.18e-05	2	120	2	25150591
Pubmed	Localized changes to glycogen synthase kinase-3 and collapsin response mediator protein-2 in the Huntington's disease affected brain.	DPYSL2 GSK3B	1.18e-05	2	120	2	24634145
Pubmed	ARID1 proteins: from transcriptional and post-translational regulation to carcinogenesis and potential therapeutics.	ARID1A ARID1B	1.18e-05	2	120	2	33890484
Pubmed	Norcantharidin inhibits proliferation and promotes apoptosis via c-Met/Akt/mTOR pathway in human osteosarcoma cells.	MET MTOR	1.18e-05	2	120	2	30520540
Pubmed	MET Oncogene Controls Invasive Growth by Coupling with NMDA Receptor.	GRIN2B MET	1.18e-05	2	120	2	36139568
Pubmed	ARID1B is a specific vulnerability in ARID1A-mutant cancers.	ARID1A ARID1B	1.18e-05	2	120	2	24562383
Pubmed	Common genetic variants near the Brittle Cornea Syndrome locus ZNF469 influence the blinding disease risk factor central corneal thickness.	FOXO1 ZNF469	1.18e-05	2	120	2	20485516
Pubmed	Emodin Alleviates Hydrogen Peroxide-Induced Inflammation and Oxidative Stress via Mitochondrial Dysfunction by Inhibiting the PI3K/mTOR/GSK3β Pathway in Neuroblastoma SH-SY5Y Cells.	GSK3B MTOR	1.18e-05	2	120	2	32832542
Pubmed	Functional variants in DPYSL2 sequence increase risk of schizophrenia and suggest a link to mTOR signaling.	DPYSL2 MTOR	1.18e-05	2	120	2	25416705
Pubmed	The relationship between preptin, Forkhead box protein O1 and mechanistic target of rapamycin levels in prediabetic patients.	FOXO1 MTOR	1.18e-05	2	120	2	28685544
Pubmed	Overexpression of EphB2 in hippocampus rescues impaired NMDA receptors trafficking and cognitive dysfunction in Alzheimer model.	EPHB2 GRIN2B	1.18e-05	2	120	2	28358367
Pubmed	ARID1B as a Potential Therapeutic Target for ARID1A-Mutant Ovarian Clear Cell Carcinoma.	ARID1A ARID1B	1.18e-05	2	120	2	29890703
Pubmed	GSK3β Controls mTOR and Prosurvival Signaling in Neurons.	GSK3B MTOR	1.18e-05	2	120	2	29143288
Pubmed	SWI/SNF factors required for cellular resistance to DNA damage include ARID1A and ARID1B and show interdependent protein stability.	ARID1A ARID1B	1.18e-05	2	120	2	24788099
Pubmed	Rhox homeobox gene cluster: recent duplication of three family members.	RHOXF2 RHOXF2B	1.18e-05	2	120	2	16496311
Pubmed	Establishment and characterization of VOA1066 cells: An undifferentiated endometrial carcinoma cell line.	ARID1A ARID1B	1.18e-05	2	120	2	33052929
Pubmed	Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.	ARID1A ARID1B	1.18e-05	2	120	2	27562491
Pubmed	Numb is an endocytic protein.	DPYSL2 NUMB	1.18e-05	2	120	2	11121447
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	ILRUN FOXO1 ARCN1 GSK3B MRTFB AP2A1 MTOR RNF10 AGFG1 NUMB MPHOSPH9 ARL14EP GNAS CNOT4	1.45e-05	1038	120	14	26673895
Pubmed	Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.	GRIN2B CUBN ZNF292 DNAH11	1.50e-05	43	120	4	21116278
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	UBQLN4 MRTFB SALL1 SATB1 BRCA2 RAB3GAP2 ARL14EP MGA NPAT	1.55e-05	418	120	9	34709266
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	DPYSL2 UBQLN4 CUL7 RAB3GAP2 POLI GNAS CDH13 TBCD	1.69e-05	322	120	8	26514267
Pubmed	Homozygous loss of BHD causes early embryonic lethality and kidney tumor development with activation of mTORC1 and mTORC2.	FOXO1 GSK3B MTOR	1.77e-05	15	120	3	19850877
Pubmed	Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.	EPHB2 DPYSL2 ZNF207 ARID1A ARCN1 MRTFB AP2A1 IGHA1 MTOR SUPT16H C1QBP SERPINB1 TMPO NUMB GNAS TBCD	1.97e-05	1367	120	16	32687490
Pubmed	Hdac2 regulates the cardiac hypertrophic response by modulating Gsk3 beta activity.	FOXO1 GSK3B MTOR	2.63e-05	17	120	3	17322895
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DPYSL2 SYT3 ITSN1 GRIN2B VIRMA GSK3B AP2A1 MTOR SUPT16H STON2 MGA UNC79 NUP153	2.96e-05	963	120	13	28671696
Pubmed	Human variation in alcohol response is influenced by variation in neuronal signaling genes.	NLGN1 GRIN2B ENTPD4 GNAS CDH13 FOXC2	2.97e-05	171	120	6	20201926
Pubmed	Human transcription factor protein interaction networks.	NCOA6 CUL7 ARID1A CREBBP PCF11 ARID1B TADA1 SALL1 UBN1 SATB1 C1QBP HELZ TAF2 MGA TRAPPC9 NPAT	3.36e-05	1429	120	16	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	DPYSL2 SYT3 ITSN1 BCAN GRIN2B ARID1A VIRMA ARCN1 GSK3B AP2A1 STON2 TMPO PLEKHA7 TRAPPC9 SDCBP DNAH11	3.42e-05	1431	120	16	37142655
Pubmed	Two Pairs of ON and OFF Retinal Ganglion Cells Are Defined by Intersectional Patterns of Transcription Factor Expression.	SALL1 SATB1 PITX3 CDH13	3.46e-05	53	120	4	27210758
Pubmed	Hydrogen peroxide/ceramide/Akt signaling axis play a critical role in the antileukemic potential of sanguinarine.	GSK3B MTOR	3.53e-05	3	120	2	27154977
Pubmed	miR-199a-3p displays tumor suppressor functions in papillary thyroid carcinoma.	MET MTOR	3.53e-05	3	120	2	24810336
Pubmed	FOXO1 Suppression is a Determinant of Acquired Lapatinib-Resistance in HER2-Positive Gastric Cancer Cells Through MET Upregulation.	FOXO1 MET	3.53e-05	3	120	2	28343375
Pubmed	Dynamics of expression of ARID1A and ARID1B subunits in mouse embryos and in cells during the cell cycle.	ARID1A ARID1B	3.53e-05	3	120	2	21647563
Pubmed	A PI3K- and GTPase-independent Rac1-mTOR mechanism mediates MET-driven anchorage-independent cell growth but not migration.	MET MTOR	3.53e-05	3	120	2	32576681
Pubmed	Decreased ZMIZ1 suppresses melanogenesis in vitiligo by regulating mTOR/AKT/GSK-3β-mediated glucose uptake.	GSK3B MTOR	3.53e-05	3	120	2	38117454
Pubmed	The rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development.	RHOXF2 RHOXF2B	3.53e-05	3	120	2	18562707
Pubmed	MiR-1 inhibits prostate cancer PC3 cells proliferation through the Akt/mTOR signaling pathway by binding to c-Met.	MET MTOR	3.53e-05	3	120	2	30551391
Pubmed	Dioscin ameliorates cardiac hypertrophy through inhibition of the MAPK and Akt/GSK3β/mTOR pathways.	GSK3B MTOR	3.53e-05	3	120	2	30125581
Pubmed	GSK-3α/β-mediated phosphorylation of CRMP-2 regulates activity-dependent dendritic growth.	DPYSL2 GSK3B	3.53e-05	3	120	2	23470087
Pubmed	GD3 synthase regulates epithelial-mesenchymal transition and metastasis in breast cancer.	MET FOXC2	3.53e-05	3	120	2	25109336
Pubmed	Phosphorylation by Rho kinase regulates CRMP-2 activity in growth cones.	DPYSL2 NUMB	3.53e-05	3	120	2	16260611
Pubmed	A human SPT3-TAFII31-GCN5-L acetylase complex distinct from transcription factor IID.	TADA1 TAF2	3.53e-05	3	120	2	9726987
Pubmed	The miR-491-3p/mTORC2/FOXO1 regulatory loop modulates chemo-sensitivity in human tongue cancer.	FOXO1 MTOR	3.53e-05	3	120	2	25749387
Pubmed	Insulin-like growth factor-1 (IGF-1) inversely regulates atrophy-induced genes via the phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) pathway.	FOXO1 MTOR	3.53e-05	3	120	2	15550386
Pubmed	Forkhead box protein O1 negatively regulates skeletal myocyte differentiation through degradation of mammalian target of rapamycin pathway components.	FOXO1 MTOR	3.53e-05	3	120	2	18079193
Pubmed	The AKT-independent MET-V-ATPase-MTOR axis suppresses liver cancer vaccination.	MET MTOR	3.53e-05	3	120	2	32764535
Interaction	NUP35 interactions	NCOA6 ZNF207 CUL7 BCAR1 ARID1A CREBBP NCOA5 PCF11 ARID1B NUP210 TMPO HELZ NUP153	1.24e-06	424	118	13	int:NUP35
Interaction	NUP43 interactions	NCOA6 CUL7 ARID1A VIRMA RYR2 ARID1B MRTFB BRCA2 RAB3GAP2 SUPT16H TAF2 MGA NUP153 ZNF292 NPAT	3.78e-06	625	118	15	int:NUP43
Interaction	SOX7 interactions	ARID1A CREBBP ARID1B SALL1 ZNF518B ZNF292	8.64e-06	82	118	6	int:SOX7
Interaction	PPARGC1A interactions	FOXO1 NCOA6 VIRMA CREBBP GSK3B USF2	8.64e-06	82	118	6	int:PPARGC1A
Interaction	SEPTIN6 interactions	EPHB2 DPYSL2 AXL GRIN2B CUL7 VIRMA	1.30e-05	88	118	6	int:SEPTIN6
Interaction	TLE3 interactions	ZNF207 ARID1A VIRMA CREBBP ARCN1 GSK3B ARID1B SALL1 BRCA2 HELZ CNOT4	1.33e-05	376	118	11	int:TLE3
Interaction	H4C2 interactions	CUL7 VIRMA SUPT16H TMPO NPAT	1.59e-05	54	118	5	int:H4C2
Interaction	H4C12 interactions	CUL7 VIRMA SUPT16H TMPO NPAT	1.59e-05	54	118	5	int:H4C12
Interaction	EPS15L1 interactions	AXL ITSN1 VIRMA AP2A1 STON2 AGFG1 NUMB	1.70e-05	138	118	7	int:EPS15L1
Interaction	HYOU1 interactions	EPHB2 TMEM67 AXL CUL7 BCAR1 VIRMA MET DNAJC10 IGHA1 TMPO	1.75e-05	317	118	10	int:HYOU1
Interaction	EP300 interactions	FOXO1 NCOA6 ARID1A VIRMA CREBBP ARCN1 ZNF469 UBN1 SATB1 AP2A1 BRCA2 SETSIP MTOR SUPT16H STON2 POLI C1QBP TMPO MAML2 USF2 CNOT4 NPAS2	1.88e-05	1401	118	22	int:EP300
Interaction	TPRX2 interactions	NCOA6 ARID1A CREBBP ARID1B SALL1	1.90e-05	56	118	5	int:TPRX2
Interaction	YAP1 interactions	FOXO1 NCOA6 DPYSL2 ARID1A CREBBP GSK3B ARID1B MRTFB DNAJC10 RAB3GAP2 SUPT16H RNF38 TMPO NUMB TAF2 GNAS MGA CNOT4 SDCBP	1.95e-05	1095	118	19	int:YAP1
Interaction	FGFR1 interactions	DOCK1 ITSN1 BCAN BCAR1 VIRMA CREBBP ARCN1 TGFBR3 MET AP2A1 RAB3GAP2 AGFG1 PLEKHA7 TRAPPC9	2.00e-05	632	118	14	int:FGFR1
Interaction	MEA1 interactions	RALGAPB BCAR1 AP2A1 NUP153	2.05e-05	28	118	4	int:MEA1
Interaction	SOX9 interactions	NCOA6 ARID1A VIRMA CREBBP GSK3B ARID1B	2.27e-05	97	118	6	int:SOX9
Interaction	PCDH8 interactions	UBQLN4 GRIN2B MET	2.28e-05	10	118	3	int:PCDH8
Interaction	DTX2 interactions	RHOXF2 UBQLN4 NCOA5 PCF11 PITX3 SUPT16H TMPO NUMB PLEKHA7 NUP153	2.47e-05	330	118	10	int:DTX2
Interaction	FEV interactions	NCOA6 ARID1A CREBBP ARID1B SALL1 SATB1 TAF2 MGA	2.62e-05	203	118	8	int:FEV
Interaction	TNRC6A interactions	NCOA6 ARID1A GSK3B PCF11 AP2A1 GLDC HELZ MPHOSPH9 CNOT4	4.05e-05	280	118	9	int:TNRC6A
Interaction	SEPTIN3 interactions	EPHB2 DPYSL2 GRIN2B CREBBP SDCBP	4.25e-05	66	118	5	int:SEPTIN3
Interaction	SMARCC2 interactions	ITSN1 ARID1A VIRMA CREBBP ARID1B UBN1 GLDC RAB3GAP2 SUPT16H NUP153	4.37e-05	353	118	10	int:SMARCC2
Interaction	H4C6 interactions	CUL7 SUPT16H TMPO GNAS NPAT	5.27e-05	69	118	5	int:H4C6
Interaction	YWHAH interactions	FOXO1 NCOA6 RALGAPB BCAR1 VIRMA CREBBP FAM83B MTOR RAB3GAP2 RNF10 AGFG1 C1QBP NUMB MPHOSPH9 ARL14EP PLEKHA7 TRAPPC9 CNOT4	7.24e-05	1102	118	18	int:YWHAH
Interaction	NUP210 interactions	CUL7 BCAR1 VIRMA MET DNAJC10 NUP210 NUP153	7.47e-05	174	118	7	int:NUP210
Interaction	AP1B1 interactions	DPYSL2 ITSN1 VIRMA CREBBP GSK3B AP2A1 STON2 NUMB	7.83e-05	237	118	8	int:AP1B1
Interaction	GPR158 interactions	GRIN2B VIRMA MET	8.46e-05	15	118	3	int:GPR158
Interaction	YWHAQ interactions	FOXO1 NCOA6 UBQLN4 CUL7 BCAR1 VIRMA FAM83B MTOR AGFG1 C1QBP TMPO NUMB MPHOSPH9 ARL14EP PLEKHA7 UNC79 CNOT4 TBCD	8.70e-05	1118	118	18	int:YWHAQ
Interaction	RNF138 interactions	ARID1A ARID1B SMPDL3B GLDC TMPO TRAPPC9	9.44e-05	125	118	6	int:RNF138
Interaction	CLTB interactions	DPYSL2 ITSN1 FAM83B AP2A1 STON2 AGFG1 NUMB	1.10e-04	185	118	7	int:CLTB
Interaction	SMG7 interactions	NCOA6 ARID1A CREBBP GSK3B PCF11 ARID1B SALL1 AP2A1 HELZ	1.10e-04	319	118	9	int:SMG7
Interaction	CLTC interactions	DPYSL2 ITSN1 GRIN2B CUL7 VIRMA GSK3B FAM83B AP2A1 GLDC STON2 TMPO NUMB HELZ	1.22e-04	655	118	13	int:CLTC
Interaction	MAML2 interactions	VIRMA CREBBP MAML2	1.25e-04	17	118	3	int:MAML2
Interaction	CRX interactions	RHOXF2 ARID1A CREBBP ARID1B SALL1 MGA SDCBP NPAS2	1.26e-04	254	118	8	int:CRX
Interaction	SHC2 interactions	AXL GRIN2B MET AP2A1	1.27e-04	44	118	4	int:SHC2
Interaction	IRF1 interactions	ARID1A CREBBP GSK3B ARID1B MGA	1.27e-04	83	118	5	int:IRF1
Interaction	HNF1B interactions	ARID1A CREBBP ARID1B UBN1 SATB1 TMPO MGA	1.29e-04	190	118	7	int:HNF1B
Interaction	SLX4 interactions	BCAR1 VIRMA CREBBP GSK3B SALL1 UBN1 AP2A1 BRCA2 SUPT16H ZNF518B MGA NUP153	1.35e-04	572	118	12	int:SLX4
Interaction	ABL1 interactions	EPHB2 BCAR1 VIRMA AP2A1 BRCA2 MTOR STON2 TMPO	1.45e-04	259	118	8	int:ABL1
Interaction	PHIP interactions	CUL7 BCAR1 VIRMA SUPT16H TMPO HELZ TAF2	1.62e-04	197	118	7	int:PHIP
Interaction	TNRC6C interactions	ITSN1 BCAR1 VIRMA AP2A1 HELZ MPHOSPH9	1.63e-04	138	118	6	int:TNRC6C
Interaction	RALBP1 interactions	DOCK1 ITSN1 AP2A1 RAB3GAP2 TMPO NUMB GNAS	1.67e-04	198	118	7	int:RALBP1
Interaction	SRF interactions	NCOA6 CREBBP ATF6 MRTFB TMPO ZNF292	1.69e-04	139	118	6	int:SRF
Interaction	KDM5C interactions	DEF8 VIRMA BRCA2 MTOR MGA CNOT4	1.69e-04	139	118	6	int:KDM5C
Interaction	GATA2 interactions	NCOA6 ARID1A CREBBP ARID1B SALL1 SATB1 TRAPPC9	1.72e-04	199	118	7	int:GATA2
Interaction	KCNH1 interactions	CUL7 BCAR1 SDCBP	1.77e-04	19	118	3	int:KCNH1
Interaction	SDC2 interactions	EPHB2 DOCK1 VIRMA TGFBR3 TMPO SDCBP	1.97e-04	143	118	6	int:SDC2
Interaction	ICOSLG interactions	AXL VIRMA UPK3BL1	2.07e-04	20	118	3	int:ICOSLG
Interaction	H4C3 interactions	CUL7 VIRMA TMPO NPAT	2.09e-04	50	118	4	int:H4C3
Interaction	SGIP1 interactions	ITSN1 RALGAPB GRIN2B AP2A1	2.09e-04	50	118	4	int:SGIP1
Interaction	HNF4A interactions	FOXO1 NCOA6 ARID1A CREBBP ARID1B TADA1 UBN1 MGA	2.18e-04	275	118	8	int:HNF4A
Interaction	DNAJB11 interactions	AXL ITSN1 UBQLN4 CUL7 VIRMA MET DNAJC10 NUP210 TMPO	2.25e-04	351	118	9	int:DNAJB11
Interaction	SMC5 interactions	NCOA6 ZNF207 BCAR1 ARID1A PCF11 ARID1B SALL1 UBN1 BRCA2 SUPT16H AGFG1 C1QBP TMPO MGA NUP153 NPAT	2.39e-04	1000	118	16	int:SMC5
Interaction	HOXA11 interactions	FOXO1 CREBBP ZNF292	2.41e-04	21	118	3	int:HOXA11
Interaction	EWSR1 interactions	NCOA6 RHOXF2 ZNF207 CUL7 ARID1A VIRMA CREBBP GSK3B PCF11 BRCA2 GLDC NUP210 SUPT16H SDCBP ZNF292	2.64e-04	906	118	15	int:EWSR1
Interaction	ATG9A interactions	DOCK1 ITSN1 FAM83B DNAJC10 AP2A1 STON2 AGFG1 TMPO NUMB TRAPPC9	2.90e-04	445	118	10	int:ATG9A
Interaction	TFCP2L1 interactions	UBQLN4 ARID1A SALL1 SUPT16H MGA	2.92e-04	99	118	5	int:TFCP2L1
Interaction	SMAD3 interactions	FOXO1 NCOA6 UBQLN4 ARID1A CREBBP GSK3B ARID1B BRCA2 TAF2 NUP153	3.01e-04	447	118	10	int:SMAD3
Interaction	KDM5B interactions	GRIN2B VIRMA ARID1B TAF2 FOXC2	3.05e-04	100	118	5	int:KDM5B
Interaction	GPR179 interactions	FOXO1 BRCA2	3.36e-04	5	118	2	int:GPR179
Interaction	YWHAG interactions	FOXO1 NCOA6 RALGAPB CUL7 BCAR1 VIRMA FAM83B MTOR AGFG1 C1QBP NUMB HELZ MPHOSPH9 ARL14EP GNAS PLEKHA7 TRAPPC9 CNOT4	3.39e-04	1248	118	18	int:YWHAG
Interaction	RHOJ interactions	RALGAPB CUL7 FAM83B MET MTOR SUPT16H STON2 AGFG1 TMPO NUMB GNAS SDCBP	3.42e-04	633	118	12	int:RHOJ
Interaction	AP2B1 interactions	ITSN1 RALGAPB VIRMA GSK3B AP2A1 STON2 AGFG1 TMPO NUMB	3.52e-04	373	118	9	int:AP2B1
Interaction	OTUD7A interactions	ITSN1 GRIN2B BCAR1 VIRMA	3.71e-04	58	118	4	int:OTUD7A
Interaction	H4C13 interactions	CUL7 SUPT16H TMPO NPAT	3.71e-04	58	118	4	int:H4C13
Interaction	NFYA interactions	BCAR1 CREBBP ATF6 SERPINB1 USF2	3.83e-04	105	118	5	int:NFYA
Interaction	PPP1CC interactions	DPYSL2 GRIN2B CUL7 VIRMA CREBBP GSK3B RYR2 FAM83B NCOA5 AP2A1 SUPT16H TMPO NUP153	3.88e-04	738	118	13	int:PPP1CC
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	EPHB2 DOCK1 ITSN1 CREBBP GSK3B PCF11 TGFBR3 BRCA2 AGFG1 NUMB HELZ MPHOSPH9 CNOT4 NUP153 ZNF292 NPAT	1.70e-06	856	119	16	M4500
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	FOXO1 CREBBP PCF11 SATB1 HELZ CNOT4 NUP153 NPAS2 NPAT	9.62e-06	300	119	9	M8702
Coexpression	GSE14415_FOXP3_KO_NATURAL_TREG_VS_TCONV_DN	TGFBR3 SATB1 POLI RNF38 MGA DSE ZNF292	1.45e-05	173	119	7	M2953
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_top-relative-expression-ranked_1000	DOCK1 DPYSL2 NPAS3 ZNF207 HHIP SPPL2A SALL1 SATB1 PROKR2 SUPT16H RNF38 ZNF518B CRISPLD1 UPK3BL1 ZNF292	3.34e-05	806	116	15	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	EPHB2 NCOA6 POGK NPAS3 NLGN1 VIRMA MRTFB BRCA2 NUP210 SUPT16H RNF38 MPHOSPH9 ARL14EP CNOT4 ZNF292	4.73e-05	831	116	15	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#5_top-relative-expression-ranked_500	NPAS3 HHIP PROKR2 AGFG1 CHSY3 CRISPLD1	7.69e-05	129	116	6	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_500_k5
CoexpressionAtlas	dev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500	ISLR TGFBR3 HHIP PROKR2 SERPINB1 DSE	8.02e-05	130	116	6	gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k-means-cluster#2_top-relative-expression-ranked_1000	DOCK1 ZNF207 CREBBP GSK3B RYR2 HHIP SPPL2A RNF38 ZNF518B	8.42e-05	330	116	9	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_k2_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500	EPHB2 NPAS3 NLGN1 SALL1 BRCA2 GLDC NUP210 SUPT16H STON2 MPHOSPH9 USF2	9.06e-05	498	116	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000	EPHB2 ILRUN NCOA6 POGK NPAS3 NLGN1 SALL1 DNAJC10 BRCA2 GLDC NUP210 SUPT16H STON2 MPHOSPH9 USF2 ZNF292	9.50e-05	989	116	16	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_top-relative-expression-ranked_1000	DOCK1 NPAS3 ZNF207 CREBBP GSK3B RYR2 HHIP SPPL2A SALL1 PROKR2 RNF38 CHSY3 ZNF518B CRISPLD1	1.51e-04	818	116	14	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-6689_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder mesenchyme_emap-3087_k-means-cluster#4_top-relative-expression-ranked_1000	NPAS3 PROKR2 TMPO CHSY3 ARL14EP DSE ZNF292	1.76e-04	214	116	7	gudmap_developingLowerUrinaryTract_e13.5_bladder mesenchyme_1000_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ Genital tubercle M_emap-6706_top-relative-expression-ranked_1000	NPAS3 PCF11 PHEX SALL1 SATB1 PROKR2 SUPT16H TMPO CHSY3 ZNF518B TAF2 CRISPLD1 DSE ZNF292	1.89e-04	836	116	14	gudmap_developingLowerUrinaryTract_e14.5_ Genital tubercle M_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k-means-cluster#3_top-relative-expression-ranked_1000	DOCK1 DPYSL2 ZNF207 HHIP SPPL2A SUPT16H RNF38 ZNF518B ZNF292	1.95e-04	369	116	9	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30902_k3_1000
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	FOXO1 NLGN1 DNAAF9 CUBN ARID1B MAML2 PLEKHA7 TRAPPC9	5.31e-08	192	120	8	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 DOCK1 DCDC1 NLGN1 MET MAML2 PLEKHH2	8.83e-07	191	120	7	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_myofibroblast\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FOXO1 CDHR3 NPAS3 ISLR RYR2 TGFBR3 PLEKHH2	1.09e-06	197	120	7	6d0d68d460243a0259ada93ebda40fa7b3088eeb
ToppCell	Parenchyma_Control_(B.)\|World / Sample group, Lineage and Cell type	DPYSL2 AXL PCF11 ARID1B AGFG1 GNAS USF2	1.20e-06	200	120	7	220b6e5f936b3d08b031d6cabc5793213b98b8e2
ToppCell	E18.5-samps-Mesenchymal-Myofibroblast\|E18.5-samps / Age Group, Lineage, Cell class and subclass	TMEM67 ITSN1 NPAS3 NLGN1 TGFBR3 HHIP	1.04e-05	183	120	6	de08f9ea02b7244d5a8788064631d10f06565337
ToppCell	facs-BAT-Fat-3m\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXO1 ZNF207 PCF11 SPPL2A SATB1 SDCBP	1.25e-05	189	120	6	7ce71f9c81512ed38c804f025908746b4af3aab1
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FOXO1 ARID1B MAML2 PLEKHA7 TRAPPC9 EPB42	1.40e-05	193	120	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	LV-01._Fibroblast_I\|LV / Chamber and Cluster_Paper	FOXO1 AXL NPAS3 TGFBR3 MAML2 PLEKHH2	1.40e-05	193	120	6	dc17f3b9758936d428cf17f77a1ce6d4c479b165
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NLGN1 CUBN MET GLDC PLEKHA7 NPAS2	1.44e-05	194	120	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	facs-Lung-3m\|Lung / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	AXL GSK3B TGFBR3 HHIP ARID1B DSE	1.49e-05	195	120	6	c4648c0332c3826776f9ad3f5f803dbac2b4c0c0
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MET UBN1 PITX3 C1QBP GNAS SLC38A3	1.53e-05	196	120	6	3dc6394c5de1f875a19ad0e8799827fad29f8f02
ToppCell	facs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GRIN2B CUBN RYR2 CAPN11 BRCA2	5.06e-05	148	120	5	5983c4546f527a0b599cfcbd8a6cb937a1d6f895
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TMEM67 BCAN ATF6 ARL14EP MAML2	9.22e-05	168	120	5	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	TGFBR3 TMPO PLEKHH2 CNOT4 ZNF292	9.48e-05	169	120	5	84b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NLGN1 CUBN RYR2 UNC79 DNAH11	9.48e-05	169	120	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	TCGA-Brain-Primary_Tumor\|TCGA-Brain / Sample_Type by Project: Shred V9	NPAS3 BCAN GLDC MAML2 CNOT4	1.06e-04	173	120	5	f6ba22661e67c17d49d1058d4170ba8f36bf47f0
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FOXO1 TGFBR3 MAML2 PLEKHH2 DSE	1.12e-04	175	120	5	1799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	NLGN1 CUBN MET SATB1 NPAS2	1.15e-04	176	120	5	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM67 TGFBR3 HHIP SALL1 PLEKHH2	1.18e-04	177	120	5	e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell	3'_v3\|World / Manually curated celltypes from each tissue	DPYSL2 ARID1B IGHA1 GNAS UPK3BL1	1.21e-04	178	120	5	42502f14d9c756df8104900ac6484477b885d3d9
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	NPAS3 GRIN2B PKD1L3 STON2 FOXC2	1.21e-04	178	120	5	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RALGAPB CUL7 BCAR1 TGFBR3 MGA	1.24e-04	179	120	5	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	356C-Myeloid-Macrophage-SPP1+_Macrophage_2\|356C / Donor, Lineage, Cell class and subclass (all cells)	EPHB2 AXL VHLL USF2 DSE	1.27e-04	180	120	5	b94618c1c2592ecf7da3535294aee9243755247a
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CDHR3 NLGN1 CUBN MET GLDC	1.27e-04	180	120	5	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ISLR RYR2 TGFBR3 PLEKHH2 EPB42	1.31e-04	181	120	5	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 BCAN MAML2 PLEKHH2 DNAH11	1.34e-04	182	120	5	8a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 BCAN MAML2 PLEKHH2 DNAH11	1.34e-04	182	120	5	a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 BCAN MAML2 PLEKHH2 DNAH11	1.34e-04	182	120	5	831b5ce46b41efe01c4db6016c2f43148611373d
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NLGN1 CUBN FAM83B MET GLDC	1.34e-04	182	120	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 BCAN MAML2 PLEKHH2 DNAH11	1.34e-04	182	120	5	e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CDHR3 NLGN1 CUBN SALL1 PLEKHA7	1.38e-04	183	120	5	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 TGFBR3 MET HHIP FOXC2	1.38e-04	183	120	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 BCAN MAML2 PLEKHH2 DNAH11	1.45e-04	185	120	5	efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 BCAN MAML2 PLEKHH2 DNAH11	1.45e-04	185	120	5	2e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	EPHB2 ITSN1 NPAS3 STON2 AGFG1	1.45e-04	185	120	5	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 BCAN MAML2 PLEKHH2 DNAH11	1.45e-04	185	120	5	7aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 BCAN MAML2 PLEKHH2 DNAH11	1.45e-04	185	120	5	fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1A ARID1B GLDC MPHOSPH9 TRAPPC9	1.48e-04	186	120	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC1 NLGN1 MAML2 PLEKHH2 DNAH11	1.48e-04	186	120	5	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	NPAS3 NLGN1 GRIN2B SALL1 UNC79	1.48e-04	186	120	5	bdc87e4631a8ea73e262e541aa84a28f24c94b00
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARID1A ARID1B GLDC MPHOSPH9 TRAPPC9	1.48e-04	186	120	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_1_/_Segment_2\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NLGN1 CUBN PLEKHA7 NPAS2	1.48e-04	186	120	5	5784d255e9ca449d375d81938d0fbbd8a7eb44f6
ToppCell	3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	AXL HHIP PLEKHH2 SLC38A3 DSE	1.48e-04	186	120	5	d3509a579871ba6a8c4edd6137b28f271c9dbe70
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	NLGN1 CUBN GLDC PLEKHA7 NPAS2	1.48e-04	186	120	5	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	FOXO1 AXL TGFBR3 MAML2 PLEKHH2	1.52e-04	187	120	5	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NLGN1 CUBN FAM83B GLDC PLEKHA7	1.52e-04	187	120	5	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NLGN1 TGFBR3 HHIP PLEKHH2 CDH13	1.52e-04	187	120	5	173f029dcf32af008f517912f6d110a33a9e98cf
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	NPAS3 GRIN2B PKD1L3 STON2 FOXC2	1.52e-04	187	120	5	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FOXO1 RYR2 TGFBR3 RNF38 CDH13	1.56e-04	188	120	5	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FOXO1 RYR2 TGFBR3 RNF38 CDH13	1.56e-04	188	120	5	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FOXO1 RYR2 TGFBR3 RNF38 CDH13	1.56e-04	188	120	5	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NPAS3 GRIN2B BCAR1 STON2 FOXC2	1.56e-04	188	120	5	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	NCOA6 RALGAPB ISLR NCOA5 ZNF469	1.56e-04	188	120	5	14bc73cf79c79c9f208369fd8d498e5b26e0114d
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	DOCK1 ITSN1 GSK3B MAML2 UNC79	1.56e-04	188	120	5	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC1 NLGN1 MAML2 PLEKHH2 DNAH11	1.60e-04	189	120	5	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC1 CDHR3 NLGN1 MET PLEKHA7	1.60e-04	189	120	5	3b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK1 ARID1B MAML2 PLEKHH2 PLEKHA7	1.60e-04	189	120	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC1 CDHR3 NLGN1 CUBN MET	1.60e-04	189	120	5	28b502611829e4a24caff2562545c7db97686099
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 STON2 MAML2 PLEKHA7 SLC38A3	1.64e-04	190	120	5	78cc6c28b31de041c24175a98f47da256ecc15a2
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FOXO1 STON2 PLEKHA7 SLC38A3	1.64e-04	190	120	5	3a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro1_(4)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	NPAS3 ISLR RYR2 PHEX TGFBR3	1.64e-04	190	120	5	7986586b7c82e91c71102cc8c4d7a689ae63ab4d
ToppCell	Control-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	FOXO1 NLGN1 MET MRTFB NPAS2	1.64e-04	190	120	5	4e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	NPAS3 GRIN2B PKD1L3 STON2 FOXC2	1.64e-04	190	120	5	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Astro-Astrocyte\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 STON2 MAML2 PLEKHA7 SLC38A3	1.64e-04	190	120	5	e67d9400467b438592690b23d681e6c2fb8f09fd
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK1 FOXO1 STON2 PLEKHA7 SLC38A3	1.64e-04	190	120	5	1c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NLGN1 CUBN PLEKHA7 NPAS2	1.68e-04	191	120	5	3c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CDHR3 NLGN1 CUBN PLEKHA7 NPAS2	1.68e-04	191	120	5	1c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RYR2 PHEX TGFBR3 HHIP PLEKHH2	1.68e-04	191	120	5	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_adventitial_fibro_(10)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	EPHB2 ISLR GRIN2B RYR2 PHEX	1.68e-04	191	120	5	156b467187331ac6ca390d6ca861d9670bb7b956
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FOXO1 AXL STON2 PLEKHA7 SLC38A3	1.72e-04	192	120	5	43beaac1de99b9c1a6dab4a450b4e81286987b64
ToppCell	Fibroblasts-CD55+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	AXL ISLR MET HHIP CDH13	1.76e-04	193	120	5	8f4bf9a2fbedae35432dad96730b00c70185874c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 FOXO1 DCDC1 NLGN1 MET	1.76e-04	193	120	5	ca7c0a4ceb05bced90f6cdc53d278e547fb241e9
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TMEM67 DCDC1 CDHR3 MRTFB DNAH11	1.76e-04	193	120	5	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FOXO1 RYR2 PHEX TGFBR3 PLEKHH2	1.81e-04	194	120	5	e93de9428c986b8943fc169258847c650cfab0e5
ToppCell	LV-02._Fibroblast_II\|LV / Chamber and Cluster_Paper	FOXO1 AXL TGFBR3 MAML2 PLEKHH2	1.81e-04	194	120	5	014d2feb5db2a6a35ef759761a41e466e108c3c1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DCDC1 MET MAML2 PLEKHH2 PLEKHA7	1.81e-04	194	120	5	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	PND07-28-samps-Mesenchymal\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	DPYSL2 ISLR PHEX TGFBR3 PLEKHH2	1.81e-04	194	120	5	68bcc1fe8dc8d5f23a12154fc9b41362fdef0b1d
ToppCell	LA-02._Fibroblast_II\|LA / Chamber and Cluster_Paper	FOXO1 AXL NLGN1 TGFBR3 MAML2	1.81e-04	194	120	5	234d1494c114cce77c619708bbcd8d5ce805f19b
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 ISLR GSK3B TGFBR3 GNAS	1.85e-04	195	120	5	4d63e0dca30ae57960459d2fbcba09122273e37b
ToppCell	medial-2-Hematologic-IGSF21+_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EPHB2 NPAS3 PKD1L3 STON2 PLEKHA7	1.85e-04	195	120	5	bb612979360b2322289545dda3d3c343d005ee6f
ToppCell	LA-02._Fibroblast_II\|World / Chamber and Cluster_Paper	FOXO1 AXL TGFBR3 MAML2 PLEKHH2	1.85e-04	195	120	5	a78b605b49acd8c9d68716266ca269dafcd910b9
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 ISLR GSK3B TGFBR3 GNAS	1.85e-04	195	120	5	661af601a3561fe3aacf2444ad7b8927fa88b48a
ToppCell	COVID-19-T_cells-Cycling_NK/T_cells\|COVID-19 / group, cell type (main and fine annotations)	BRCA2 NUP210 TMPO MPHOSPH9 EPB42	1.85e-04	195	120	5	764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCell	RA-02._Fibroblast_II\|RA / Chamber and Cluster_Paper	FOXO1 AXL TGFBR3 ARID1B MAML2	1.85e-04	195	120	5	6a02ebbeb3199447ddce64d92d8809436e040eba
ToppCell	medial-Hematologic-IGSF21+_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EPHB2 NPAS3 PKD1L3 STON2 PLEKHA7	1.85e-04	195	120	5	779130c2cfcbc603955b0c0332b855b22ab6e9e6
ToppCell	medial-Hematologic-IGSF21+_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	EPHB2 NPAS3 PKD1L3 STON2 PLEKHA7	1.85e-04	195	120	5	330b688d703d53cb7feb29373b5a6e6e529169ec
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIN2B RYR2 MRTFB CHSY3 UNC79	1.89e-04	196	120	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EPHB2 DCDC1 NLGN1 MET PLEKHA7	1.94e-04	197	120	5	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	facs-Diaphragm-Limb_Muscle-3m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DPYSL2 ZNF207 GSK3B PCF11 SDCBP	1.94e-04	197	120	5	b0e2ea81308bce289cb7cbea0e27de1d01afeed2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIN2B RYR2 MRTFB CHSY3 UNC79	1.99e-04	198	120	5	6d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIN2B RYR2 MRTFB GNAS UNC79	1.99e-04	198	120	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GRIN2B RYR2 MRTFB CHSY3 UNC79	1.99e-04	198	120	5	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK1 ARID1B MAML2 PLEKHA7 TRAPPC9	1.99e-04	198	120	5	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ISLR HHIP SALL1 PLEKHH2 CDH13	1.99e-04	198	120	5	75d104eead681f6bf47c4dd24913cc768c9a1717
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ISLR RYR2 PHEX PLEKHH2 CDH13	1.99e-04	198	120	5	f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ISLR RYR2 PHEX TGFBR3 PLEKHH2	2.03e-04	199	120	5	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	mild-MAIT\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	RHOXF2 TGFBR3 SATB1 HELZ PLEKHA7	2.03e-04	199	120	5	cbe1fb6d2c5fca7a1baf1ad20afcdf8e8e11bd84
ToppCell	343B-Fibroblasts-Fibroblast-G\|343B / Donor, Lineage, Cell class and subclass (all cells)	ISLR RYR2 PHEX PLEKHH2 CDH13	2.03e-04	199	120	5	f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell	343B-Fibroblasts-Fibroblast-G-\|343B / Donor, Lineage, Cell class and subclass (all cells)	ISLR RYR2 PHEX PLEKHH2 CDH13	2.03e-04	199	120	5	9c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	NPAS3 ISLR TGFBR3 PLEKHH2 CRISPLD1	2.03e-04	199	120	5	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
Drug	irinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A	FOXO1 ITSN1 CREBBP GSK3B MRTFB AGFG1 NUMB CNOT4 NPAT	3.16e-07	174	118	9	7530_DN
Drug	Camptothecine (S,+) [7689-03-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	ARID1A CREBBP MRTFB BRCA2 MGA CNOT4 NUP153 ZNF292 NPAT	5.07e-07	184	118	9	2321_DN
Drug	fluphenazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	EPHB2 TAF1C ATF6 NUP210 TMPO HELZ MGA TBCD NPAT	8.61e-07	196	118	9	1662_DN
Drug	Fenbufen [36330-85-5]; Down 200; 15.8uM; PC3; HT_HG-U133A	EPHB2 FOXO1 MET ATF6 BRCA2 AGFG1 CNOT4 ZNF292	7.05e-06	191	118	8	4279_DN
Drug	Nisoxetine hydrochloride [57754-86-6]; Up 200; 13uM; MCF7; HT_HG-U133A	TAF1C NPAS3 ENTPD4 TLR8 RYR2 PHEX MTOR CNOT4	9.18e-06	198	118	8	6496_UP
Disease	Malignant neoplasm of prostate	EPHB2 FOXO1 ITSN1 BCAR1 ARID1A CREBBP GSK3B MET DNAJC10 BRCA2 PITX3 MGA CDH13 ZNF292	1.19e-07	616	114	14	C0376358
Disease	Prostatic Neoplasms	FOXO1 ITSN1 BCAR1 ARID1A CREBBP GSK3B MET DNAJC10 BRCA2 PITX3 MGA CDH13 ZNF292	7.95e-07	616	114	13	C0033578
Disease	RS-6-hydroxywarfarin measurement	ITSN1 RYR2 ARID1B KIR3DL3 TRAPPC9 CDH13	3.19e-05	155	114	6	EFO_0803328
Disease	Neuroblastoma	ARID1A MET ARID1B GNAS	3.32e-05	47	114	4	C0027819
Disease	Endocrine System Diseases	MTOR GNAS	4.43e-05	3	114	2	C0014130
Disease	Autistic Disorder	TAF1C NLGN1 GRIN2B CUL7 MET ZNF292 NPAS2	7.19e-05	261	114	7	C0004352
Disease	keratoconus	FOXO1 GRIN2B ZNF469 MAML2	1.27e-04	66	114	4	MONDO_0015486
Disease	Malignant Neoplasms	ARID1A MET DNAJC10 MTOR GNAS	1.43e-04	128	114	5	C0006826
Disease	whole-brain volume	CUBN DNAH11	1.47e-04	5	114	2	EFO_0005089
Disease	MENTAL RETARDATION, AUTOSOMAL DOMINANT 12	ARID1A ARID1B	1.47e-04	5	114	2	C3281201
Disease	Profound Mental Retardation	GRIN2B ARL14EP TAF2 GNAS TBCD	2.10e-04	139	114	5	C0020796
Disease	Mental Retardation, Psychosocial	GRIN2B ARL14EP TAF2 GNAS TBCD	2.10e-04	139	114	5	C0025363
Disease	Mental deficiency	GRIN2B ARL14EP TAF2 GNAS TBCD	2.10e-04	139	114	5	C0917816
Disease	ascending aortic diameter	DCDC1 RYR2 CRISPLD1 TRAPPC9 CDH13	2.17e-04	140	114	5	EFO_0021787
Disease	diastolic blood pressure, systolic blood pressure	DCDC1 AXL RYR2 MET ARID1B TAF2 TRAPPC9 SDCBP CDH13 NPAS2	2.79e-04	670	114	10	EFO_0006335, EFO_0006336
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	DCDC1 NPAS3 NLGN1 RYR2 MET ARID1B DNAJC10 RAB3GAP2 HELZ UNC79 CDH13	2.80e-04	801	114	11	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	substance-related disorder (implicated_via_orthology)	GSK3B CDH13	3.07e-04	7	114	2	DOID:303 (implicated_via_orthology)
Disease	Intellectual Disability	GRIN2B MTOR SUPT16H ARL14EP TAF2 GNAS TBCD ZNF292	3.54e-04	447	114	8	C3714756
Disease	heart disease (implicated_via_orthology)	GSK3B RYR2 CNOT4	4.29e-04	38	114	3	DOID:114 (implicated_via_orthology)
Disease	Neoplasm of uncertain or unknown behavior of breast	ARID1A ARID1B BRCA2	5.38e-04	41	114	3	C0496956
Disease	Breast adenocarcinoma	ARID1A ARID1B BRCA2	5.38e-04	41	114	3	C0858252
Disease	Bipolar Disorder	DPYSL2 NPAS3 NLGN1 GRIN2B GSK3B PROKR2 BRCA2 NPAS2	5.43e-04	477	114	8	C0005586
Disease	Schizophrenia	NPAS3 NLGN1 GRIN2B GSK3B MET MTOR PITX3 STON2 GNAS MAGEC1 NPAS2	6.34e-04	883	114	11	C0036341
Disease	neuroblastoma (is_implicated_in)	ARID1A ARID1B	6.52e-04	10	114	2	DOID:769 (is_implicated_in)
Disease	urate measurement, bone density	NPAS3 THAP9 ENTPD4 SALL1 MAML2 SLC38A3 CDH13 NUP153 DNAH11	6.83e-04	619	114	9	EFO_0003923, EFO_0004531
Disease	Malignant neoplasm of kidney	AXL MET BRCA2	7.08e-04	45	114	3	C0740457
Disease	Endogenous depression	CREBBP GSK3B GNAS	7.55e-04	46	114	3	C0011573
Disease	Lymphoma, Lymphocytic, Intermediate	GSK3B MTOR	7.95e-04	11	114	2	C0751958
Disease	serum gamma-glutamyl transferase measurement	ILRUN NUP210L AXL ARID1A RYR2 MET SPPL2A SALL1 SPATA21 CNOT4 ZNF292	8.40e-04	914	114	11	EFO_0004532
Disease	corneal topography	FOXO1 ZNF469 MTOR STON2	8.60e-04	109	114	4	EFO_0004345
Disease	Depressive disorder	DPYSL2 GRIN2B GSK3B PITX3 CDH13 NPAS2	9.23e-04	289	114	6	C0011581
Disease	Malignant neoplasm of breast	MAGEA1 NCOA6 SYT3 BCAR1 CUBN ARID1A FSCB ARID1B BRCA2 MTOR SPATA21 C1QBP	9.29e-04	1074	114	12	C0006142
Disease	alcohol use disorder (implicated_via_orthology)	ARID1A CREBBP RYR2 ARID1B UNC79	9.82e-04	195	114	5	DOID:1574 (implicated_via_orthology)
Disease	Coffin-Siris syndrome	ARID1A ARID1B	1.12e-03	13	114	2	C0265338
Disease	pallidum volume change measurement	TRAPPC9 CDH13	1.12e-03	13	114	2	EFO_0021494
Disease	Malformations of Cortical Development	MTOR TBCD	1.31e-03	14	114	2	C1955869
Disease	Cortical Dysplasia	MTOR TBCD	1.31e-03	14	114	2	C0431380
Disease	high grade glioma (biomarker_via_orthology)	BCAN MET	1.50e-03	15	114	2	DOID:3070 (biomarker_via_orthology)
Disease	schizophrenia (biomarker_via_orthology)	GRIN2B GSK3B	1.50e-03	15	114	2	DOID:5419 (biomarker_via_orthology)
Disease	creatinine measurement	DCDC1 CUBN PKD1L3 ARID1A FAM83B SPPL2A NUMB GNAS PLEKHH2 PLEKHA7 CDH13	1.66e-03	995	114	11	EFO_0004518
Disease	Cardiovascular Abnormalities	ZNF292 FOXC2	1.71e-03	16	114	2	C0243050
Disease	T-Cell Lymphoma	ARID1A MGA	1.71e-03	16	114	2	C0079772
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	GSK3B MTOR	1.71e-03	16	114	2	C0334634
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	TMEM67 MTOR	1.71e-03	16	114	2	DOID:0110861 (implicated_via_orthology)
Disease	severe acute respiratory syndrome, COVID-19	EPHB2 TGFBR3 GLDC NUP210 CHSY3 MAML2 CDH13	1.79e-03	447	114	7	EFO_0000694, MONDO_0100096
Disease	cortical surface area measurement	DPYSL2 DCDC1 NPAS3 DNAAF9 HHIP ZNF469 ARID1B RAB3GAP2 AGFG1 MPHOSPH9 PLEKHA7 CNOT4 DNAH11	2.09e-03	1345	114	13	EFO_0010736
Disease	Tachycardia	RYR2 GNAS	2.17e-03	18	114	2	C0039231
Disease	Tachyarrhythmia	RYR2 GNAS	2.17e-03	18	114	2	C0080203
Disease	Malignant neoplasm of urinary bladder	ARID1A CREBBP BRCA2 MTOR	2.22e-03	141	114	4	C0005684
Disease	squamous cell carcinoma	DEF8 BRCA2 DNAH11	2.25e-03	67	114	3	EFO_0000707
Disease	polycystic kidney disease (biomarker_via_orthology)	MTOR GNAS	2.42e-03	19	114	2	DOID:0080322 (biomarker_via_orthology)
Disease	C-reactive protein measurement	ILRUN NCOA6 NUP210L CDHR3 NLGN1 TLR8 ZNF469 SALL1 RNF10 NUMB ARL14EP DNAH11	2.46e-03	1206	114	12	EFO_0004458
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	CUL7 ARID1A MET MTOR	2.65e-03	148	114	4	C0279702
Disease	neutrophil count	FOXO1 NUP210L UBQLN4 ARID1A CREBBP GSK3B MET ATF6 TADA1 SPPL2A SALL1 POLI ZNF292	2.65e-03	1382	114	13	EFO_0004833
Disease	Cleft palate	VIRMA PHEX TRAPPC9	2.65e-03	71	114	3	HP_0000175
Disease	corneal hysteresis	FOXO1 ZNF469	2.69e-03	20	114	2	EFO_0010066
Disease	Adenocarcinoma of prostate	EPHB2 BRCA2	2.69e-03	20	114	2	C0007112
Disease	breast cancer (is_implicated_in)	NCOA6 ARID1A BRCA2 CDH13	2.78e-03	150	114	4	DOID:1612 (is_implicated_in)
Disease	melanoma	MAGEA1 CUBN MET BRCA2 MAGEC1	2.81e-03	248	114	5	C0025202
Disease	risk-taking behaviour	DCDC1 UBQLN4 NLGN1 GRIN2B PKD1L3 RYR2 ARID1B UNC79 CDH13	2.89e-03	764	114	9	EFO_0008579
Disease	autism spectrum disorder (implicated_via_orthology)	NLGN1 CREBBP MET ARID1B	2.91e-03	152	114	4	DOID:0060041 (implicated_via_orthology)
Disease	Amphetamine-Related Disorders	CUBN PROKR2 CDH13	3.10e-03	75	114	3	C0236733
Disease	Amphetamine Abuse	CUBN PROKR2 CDH13	3.10e-03	75	114	3	C0236807
Disease	Amphetamine Addiction	CUBN PROKR2 CDH13	3.10e-03	75	114	3	C0236804
Disease	intellectual disability (implicated_via_orthology)	ITSN1 CAPN11 TRAPPC9	3.10e-03	75	114	3	DOID:1059 (implicated_via_orthology)
Disease	Mental Depression	DPYSL2 GRIN2B GSK3B CDH13 NPAS2	3.11e-03	254	114	5	C0011570
Disease	Non-Small Cell Lung Carcinoma	AXL MET MTOR CDH13	3.20e-03	156	114	4	C0007131
Disease	renal system measurement, blood urea nitrogen measurement	DCDC1 GNAS	3.25e-03	22	114	2	EFO_0004741, EFO_0004742
Disease	body weight	DOCK1 ILRUN FOXO1 NLGN1 VIRMA GSK3B HHIP MTOR GNAS MGA UNC79 CDH13	3.52e-03	1261	114	12	EFO_0004338
Disease	Renal glomerular disease	CREBBP SALL1	3.55e-03	23	114	2	C0268731
Disease	Glomerulopathy Assessment	CREBBP SALL1	3.55e-03	23	114	2	C4521256
Disease	sciatic neuropathy (implicated_via_orthology)	GSK3B MTOR	3.55e-03	23	114	2	DOID:11446 (implicated_via_orthology)
Disease	body surface area	ILRUN FOXO1 HHIP UBN1 MTOR GNAS UNC79 CDH13	3.55e-03	643	114	8	EFO_0022196
Disease	Liver carcinoma	MAGEA1 ARID1A MET HHIP ARID1B MTOR CDH13	3.60e-03	507	114	7	C2239176
Disease	Neoplasm of the genitourinary tract	MET BRCA2	3.86e-03	24	114	2	cv:C0042065
Disease	Intrahepatic Cholangiocarcinoma	ARID1A GNAS	3.86e-03	24	114	2	C0345905
Disease	Extrahepatic Cholangiocarcinoma	ARID1A GNAS	3.86e-03	24	114	2	C3805278
Disease	triacylglycerol 56:4 measurement	NLGN1 MAGEC1	3.86e-03	24	114	2	EFO_0010431
Disease	West Syndrome	GRIN2B TBCD	3.86e-03	24	114	2	C0037769

Protein segments in the cluster

Peptide	Gene	Start	Entry
TNQDIPAPANFSQRG	UPK3BL1	101	B0FP48
GLFFSNFERNPPENT	EPB42	546	P16452
VTFNINNSIPPTFDG	C1QBP	131	Q07021
AVDAFFTAVATNQPP	BCAR1	761	P56945
SLQFTNPGRQTEFAP	ARL14EP	151	Q8N8R7
VQFQNFSPTVVHPGD	AP2A1	786	O95782
SQFLPQNQFPSSSGA	CREBBP	791	Q92793
FQQQAFAPSILRSGP	DNAH11	2666	Q96DT5
QRFAGQNQHPSGATP	ARID1B	486	Q8NFD5
QRNQTNTFFGSPPAA	ATF6	641	P18850
NPGQSFEIHTNPQTN	CDH13	406	P55290
FTGGVAQSFQLQRPP	CAPN11	241	Q9UMQ6
AQSQTVFQNPDAHPA	NPAS2	706	Q99743
QNGNNFSTPPRQVLH	NPAT	956	Q14207
PQNQFPFQFGRDRVS	ARID1A	1451	O14497
PNQTGFPNKHSRFNV	BCAN	336	Q96GW7
PFGNSQGPSRVAQFL	RAB3GAP2	451	Q9H2M9
GITNHQNPFSFGNAV	NUP210	1191	Q8TEM1
QNPFSFGNAVPGLTF	NUP210	1196	Q8TEM1
EGFPINFNCTSQQIP	DCDC1	631	M0R2J8
QGGHFPTIFSTNPNL	FAM166C	66	A6NJV1
QSPQGASAFPTTINF	MAGEA1	56	P43355
AQSAFEGFPQSPLQI	MAGEC1	431	O60732
IQLNGPGVHTFTFPQ	MGA	216	Q8IWI9
FASEHPEFQPATNSN	FSCB	191	Q5H9T9
QQAPPVRNLHQSGFS	DPYSL2	526	Q16555
DFHPKNQFPAGSNNI	SMPDL3B	136	Q92485
HFVPNFNGPNAIRQF	FAM83B	361	Q5T0W9
PVASSQPRFQAFANG	ISLR	296	O14498
VNGVTDQSPFSPQFA	EPHB2	411	P29323
ASPSVAAGNTPNQNF	NCOA5	451	Q9HCD5
QEAVFNPQSRGPAFF	CUL7	1076	Q14999
RVNGTFQANFPLGPV	KIR3DL3	271	Q8N743
PQQFVVQHSLFGSPV	MRTFB	851	Q9ULH7
FSQASNVTSQLPGFP	MPHOSPH9	341	Q99550
EHPDQNSFTFAPNGV	DSE	451	Q9UL01
PGHTFAAQQQTFPNV	FOXC2	436	Q99958
TNQVNPFSNFLHVDP	TMPO	436	P42167
NATSQFPQPQHFDSF	POGK	136	Q9P215
NTIPGIQPLHTFNTF	NLGN1	826	Q8N2Q7
GPNNAFFNSAVAHRP	HELZ	1426	P42694
FERPFSTPAGHVTNQ	PLEKHH2	1271	Q8IVE3
PQRFDGPQHQQASRF	PCF11	1091	O94913
QFQRHEQIFDSPQGP	PCF11	1151	O94913
PANSKRPNGFVDNSF	MAML2	186	Q8IZL2
NFPSPNQSSRAFQGT	MAML2	1086	Q8IZL2
AAQSNARPQFITPVF	NCOA6	1646	Q14686
AVHFEQPFQIPNGDS	CUBN	2131	O60494
QPHRKVEGNFNPFAS	ILRUN	201	Q9H6K1
VEGNFNPFASPQKNR	ILRUN	206	Q9H6K1
NFDNVLPNQSFPHSV	FOXO1	631	Q12778
QHFIPFQPVAGENDF	DOCK1	346	Q14185
ISNSNNFEVGPPAFR	BRCA2	1831	P51587
PQATGFSPTQAVVHF	FAM83C	136	Q9BQN1
IGPGNVNNHFTFSPN	CDHR3	606	Q6ZTQ4
FQNGIFSESLQNPPG	CRISPLD1	476	Q9H336
NFFFQSGLPQPVLAQ	ITSN1	46	Q15811
QGVTARNFPPSQDAS	IGHA1	46	P01876
PNGRDTPALFNFTTQ	GSK3B	351	P49841
NSPNRQPFVLFGNHS	DNAAF9	281	Q5TEA3
FRQAHLNPFNKQSGP	DEF8	71	Q6ZN54
ENNPAGNIFISPFSI	SERPINB1	21	P30740
VNSHVTTLGPQNFPA	DNAJC10	451	Q8IXB1
PQHRFPATGLQQEEF	BMP2KL	136	Q5H9B9
PQGFHFTNSNPAVSA	POLI	641	Q9UNA4
IQAQTAFSANPANPA	SDCBP	16	O00560
FEPSSNLGPNQNSAV	SALL1	1061	Q9NSC2
PAVFAQATSPNVFQF	RYR2	1541	Q92736
PFAFNSVNVGPLASQ	PITX3	171	O75364
FSIAGQPNDFFPVQV	ARCN1	456	P48444
PSQLNVNFAGPAAHF	CROT	96	Q9UKG9
GGPQPQSIVHFSISN	NUP210L	1106	Q5VU65
PRFLQAQTFSFPFQQ	TMEM67	31	Q5HYA8
AISVPTFFFQQVQPF	MTOR	176	P42345
VVAPQSPTFQANGTD	NUMB	356	P49757
TFPEDQFPNSSQNGS	MET	1006	P08581
NPVFNETFQFSVPLA	SYT3	361	Q9BQG1
TNQDIPAPANFSQRG	UPK3BL2	101	E5RIL1
GQFVPFQTQQSRSPL	RNF38	291	Q9H0F5
PLPPNFNNTTGNFSH	SLC38A3	241	Q99624
PDIRSPFFQSGSQGN	SPATA21	436	Q7Z572
HRFQPQNPLSGAQQF	TADA1	111	Q96BN2
HFQEVVLTPGDNPQF	TAF1C	241	Q15572
ANNPSSHPQLVGFQN	TAF2	1021	Q6P1X5
SHPQLVGFQNPFSSS	TAF2	1026	Q6P1X5
PNFQVLNPAFREAGA	GNAS	76	Q5JWF2
TSLNGVYQPPIHFQN	ENTPD4	411	Q9Y227
FQNNNSLGFKVPPTV	PKD1L3	341	Q7Z443
AFRHPVTGQFSPENS	PLEKHA7	81	Q6IQ23
IPNFGVTTFVNHPQV	SETSIP	101	P0DME0
PNAHAVNFVDVNSPG	NPAS3	846	Q8IXF0
ELFVPSSNVNGQPVF	VHLL	116	Q6RSH7
GNAQQPNVHAFTPLQ	RHOXF2B	131	P0C7M4
FHAQGSAVLGQQSPP	SEC31B	781	Q9NQW1
RNEGNIFPNPEATFV	SUPT16H	581	Q9Y5B9
SNPHFNSTNQPPEVF	HHIP	411	Q96QV1
HVNFGQQPVPGNTAE	SATB1	266	Q01826
QDVQPSPINPFSAFF	STON2	321	Q8WXE9
FSGSFQQPAFPAQAA	AGFG1	486	P52594
PAQAAFPQQTAFSQQ	AGFG1	496	P52594
FPQQTAFSQQPNGAG	AGFG1	501	P52594
GRVEFFSSQQPPNAG	CHSY3	201	Q70JA7
NSTFSVLPQRFPQFQ	CNOT4	466	O95628
NSIFFIGPNQFENLP	TLR8	491	Q9NR97
PSPGFNSNIFSFLQR	THAP9	251	Q9H5L6
DNSDRVPVPSFQNSF	RNF10	751	Q8N5U6
NNSVLFPPSGNRSEF	SPPL2A	116	Q8TCT8
LPNTFPRSGVTNFNT	ZNF292	1466	O60281
PPENISATRNGSQAF	AXL	336	P30530
SPPQFRVNGAISNFE	PHEX	711	P78562
GNTSFTPNFNPPQDH	PROKR2	6	Q8NFJ6
PQAGNFVLVFPFNEA	TTLL2	551	Q9BWV7
GNAQQPNVHAFTPLQ	RHOXF2	131	Q9BQY4
FPFNQSPAAFTVGSN	NUP153	1436	P49790
FPLAVIQNPFSNGGS	USF2	141	Q15853
QPLGNEQNDFFPSVT	RALGAPB	961	Q86X10
AFTNGPLVFAFHQPQ	ZNF469	296	Q96JG9
FPSTAQAQAAVQGPV	ZNF207	286	O43670
VFHAGTQQQKNFTPP	UBN1	806	Q9NPG3
AQQAPEFSATQVFPR	TBCD	591	Q9BTW9
GPFALTVVPFQDHQN	TRAPPC9	1056	Q96Q05
SQVHPTVSNPFGINA	UBQLN4	356	Q9NRR5
HSQNRFFTPPASKGN	VIRMA	1701	Q69YN4
QVRNPSSFQEQPHGN	TGFBR3	576	Q03167
FHQLAPNGIFPQLFQ	UNC79	2086	Q9P2D8
LGAAPPNFHFVSNNS	ZNF518B	91	Q9C0D4
FANIHPFVPLDQAQG	GLDC	576	P23378
RVTQNPFIPTFGDDQ	GRIN2B	1381	Q13224