Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2 ITPR3

3.60e-0731433GO:0005220
GeneOntologyMolecularFunctionG-protein beta/gamma-subunit complex binding

GNA14 GNA11 GNAQ GNAS GNAZ

8.31e-07251435GO:0031683
GeneOntologyMolecularFunctionsemaphorin receptor activity

PLXNA3 PLXNA1 PLXNA2 PLXNB1

1.19e-06121434GO:0017154
GeneOntologyMolecularFunctionalkylglycerophosphoethanolamine phosphodiesterase activity

GNA11 GNAQ GNAS

3.56e-0651433GO:0047391
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH3 DNAH10 DYNC2H1 DNAH14

7.14e-06181434GO:0008569
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH3 DNAH10 DYNC2H1 DNAH14

4.52e-05281434GO:0051959
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2 ITPR3

1.24e-04141433GO:0070679
GeneOntologyMolecularFunctionATP-dependent activity

DNAH3 DNAH10 ATG7 MYO6 ABCA12 DYNC2H1 MYO18A ATP10B ABCC6 DNAH14 ATAD1 ABCA6 HFM1 ABCC2

1.35e-0461414314GO:0140657
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH3 DNAH10 DYNC2H1 DNAH14

1.39e-04371434GO:0045505
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

DNAH3 DNAH10 ABCA12 DYNC2H1 MYO18A ATP10B ABCC6 GNA14 ATAD1 ABCA6 HFM1 GNA11 GNAQ GNAS ABCC2 GNAZ

1.40e-0477514316GO:0017111
GeneOntologyMolecularFunctioncytoskeletal motor activity

DNAH3 DNAH10 MYO6 DYNC2H1 MYO18A DNAH14

2.07e-041181436GO:0003774
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2 ITPR3

2.71e-04181433GO:0015278
GeneOntologyMolecularFunctioncytoskeletal protein binding

RHCG MYO6 DCTN2 KTN1 NCKIPSD MYO18A ARFGEF1 NUF2 SPAG5 TTLL7 KIFAP3 DST LRRC27 SCN5A KCNMA1 CCR5 GNAS IQGAP3 MYBPC2

3.23e-04109914319GO:0008092
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH3 DNAH10 ABCA12 DYNC2H1 MYO18A ATP10B ABCC6 ATAD1 ABCA6 HFM1 ABCC2

3.41e-0444114311GO:0016887
GeneOntologyMolecularFunctionpyrophosphatase activity

DNAH3 DNAH10 ABCA12 DYNC2H1 MYO18A ATP10B ABCC6 GNA14 ATAD1 ABCA6 HFM1 GNA11 GNAQ GNAS ABCC2 GNAZ

3.42e-0483914316GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

DNAH3 DNAH10 ABCA12 DYNC2H1 MYO18A ATP10B ABCC6 GNA14 ATAD1 ABCA6 HFM1 GNA11 GNAQ GNAS ABCC2 GNAZ

3.47e-0484014316GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

DNAH3 DNAH10 ABCA12 DYNC2H1 MYO18A ATP10B ABCC6 GNA14 ATAD1 ABCA6 HFM1 GNA11 GNAQ GNAS ABCC2 GNAZ

3.47e-0484014316GO:0016818
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA12 ABCC6 ABCA6 ABCC2

4.16e-04491434GO:0140359
GeneOntologyMolecularFunctionnuclear retinoic acid receptor binding

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

6.48e-04551434GO:0042974
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC6 ABCC2

1.39e-0381432GO:0015431
GeneOntologyMolecularFunctionligand-gated calcium channel activity

ITPR1 ITPR2 ITPR3

1.40e-03311433GO:0099604
GeneOntologyMolecularFunctionmicrotubule motor activity

DNAH3 DNAH10 DYNC2H1 DNAH14

1.60e-03701434GO:0003777
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

ITPR1 ITPR2 ITPR3

1.68e-03331433GO:0005217
GeneOntologyMolecularFunctionadenylate cyclase regulator activity

GNAS GNAZ

1.77e-0391432GO:0010854
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC6 ABCC2

2.21e-03101432GO:0043225
GeneOntologyMolecularFunctionneuropeptide Y receptor activity

NPY1R PROKR1

2.68e-03111432GO:0004983
GeneOntologyMolecularFunctionubiquitin-like ligase-substrate adaptor activity

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.86e-03821434GO:1990756
GeneOntologyBiologicalProcessphospholipase C-activating dopamine receptor signaling pathway

GNA14 GNA11 GNAQ

2.50e-0591403GO:0060158
GeneOntologyBiologicalProcessmicrotubule-based process

SEMG1 SEMG2 DNAH3 SPAG1 DNAH10 DYNC2H1 DCTN2 KTN1 CNTRL RTTN HAUS3 NUF2 ARMCX3 DNAH14 SPAG5 TTLL7 KIFAP3 GDA DST CFAP69

3.14e-05105814020GO:0007017
GeneOntologyBiologicalProcessolfactory nerve formation

PLXNA3 PLXNA1

4.57e-0521402GO:0021628
GeneOntologyBiologicalProcessforebrain neuron development

PLXNA3 ATG7 GNAQ PLXNA1

4.86e-05301404GO:0021884
GeneOntologyBiologicalProcesscentral nervous system neuron development

PLXNA3 ARHGEF28 ATG7 SLIT2 GNAQ PLXNA1

5.86e-05991406GO:0021954
GeneOntologyBiologicalProcession channel modulating, G protein-coupled receptor signaling pathway

ITPR1 GNA11 GNAQ

6.44e-05121403GO:0099105
GeneOntologyBiologicalProcessphospholipase C-activating G protein-coupled acetylcholine receptor signaling pathway

ITPR1 GNA11 GNAQ

8.33e-05131403GO:0007207
GeneOntologyBiologicalProcessgerm cell development

SEMG1 SEMG2 CNTRL PRAMEF1 PRAMEF2 PRAMEF13 PIK3CA PRAMEF14 HFM1 GNAS CFAP69 VPS13B

1.13e-0448214012GO:0007281
GeneOntologyBiologicalProcesspositive regulation of serine-type peptidase activity

SEMG1 SEMG2

1.37e-0431402GO:1902573
GeneOntologyBiologicalProcessolfactory nerve morphogenesis

PLXNA3 PLXNA1

1.37e-0431402GO:0021627
GeneOntologyBiologicalProcesspositive regulation of serine-type endopeptidase activity

SEMG1 SEMG2

1.37e-0431402GO:1900005
GeneOntologyBiologicalProcessG protein-coupled dopamine receptor signaling pathway

GNA14 GNA11 GNAQ GNAS

2.24e-04441404GO:0007212
GeneOntologyBiologicalProcessregulation of hormone levels

NPY1R CYP26B1 ATG7 ABCA12 RDH13 ITPR1 SLC5A5 DHRS9 KCNMA1 GNA11 GNAQ GNAS ABCC2 GNAZ

2.36e-0468414014GO:0010817
GeneOntologyBiologicalProcesscellular process involved in reproduction in multicellular organism

SEMG1 SEMG2 CNTRL PRAMEF1 PRAMEF2 PRAMEF13 PIK3CA PRAMEF14 HFM1 GNAS CFAP69 VPS13B

2.57e-0452714012GO:0022412
GeneOntologyBiologicalProcessnegative regulation of cilium-dependent cell motility

SEMG1 SEMG2

2.72e-0441402GO:1902020
GeneOntologyBiologicalProcessnegative regulation of cilium movement

SEMG1 SEMG2

2.72e-0441402GO:0003354
GeneOntologyBiologicalProcessnegative regulation of flagellated sperm motility

SEMG1 SEMG2

2.72e-0441402GO:1901318
GeneOntologyBiologicalProcessmating plug formation

SEMG1 SEMG2

2.72e-0441402GO:0042628
GeneOntologyCellularComponentsemaphorin receptor complex

PLXNA3 PLXNA1 PLXNA2 PLXNB1

1.39e-06131424GO:0002116
GeneOntologyCellularComponentheterotrimeric G-protein complex

GNA14 GNA11 GNAQ GNAS GNAZ

3.71e-06351425GO:0005834
GeneOntologyCellularComponentGTPase complex

GNA14 GNA11 GNAQ GNAS GNAZ

8.30e-06411425GO:1905360
GeneOntologyCellularComponentcilium

DNAH3 EVC2 PTCHD3 DNAH10 ATG7 DYNC2H1 CNTRL RTTN PRAMEF1 PRAMEF2 PRAMEF13 DNAH14 SPAG5 TTLL7 KIFAP3 GNA11 GNAQ USP48 CFAP69

1.10e-0589814219GO:0005929
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2 ITPR3

2.50e-0591423GO:0031095
GeneOntologyCellularComponentdynein complex

DNAH3 DNAH10 DYNC2H1 DCTN2 DNAH14

3.26e-05541425GO:0030286
GeneOntologyCellularComponentextrinsic component of cytoplasmic side of plasma membrane

GNA14 GNA11 GNAQ GNAS GNAZ

3.90e-05561425GO:0031234
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2 ITPR3

4.87e-05111423GO:0031094
GeneOntologyCellularComponentacrosomal vesicle

SEMG1 SEMG2 PRAMEF1 PRAMEF2 PRAMEF13 ARSA PLA1A VPS13B

8.43e-052061428GO:0001669
GeneOntologyCellularComponentmicrotubule associated complex

DNAH3 DNAH10 DYNC2H1 DCTN2 HAUS3 DNAH14 KIFAP3

1.17e-041611427GO:0005875
GeneOntologyCellularComponentcytoplasmic side of membrane

ALG2 ITPR3 DST GNA14 GNA11 GNAQ GNAS GNAZ

1.80e-042301428GO:0098562
GeneOntologyCellularComponentCul2-RING ubiquitin ligase complex

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.90e-04471424GO:0031462
GeneOntologyCellularComponentplasma membrane bounded cell projection cytoplasm

DNAH3 DNAH10 ATG7 DYNC2H1 CNTRL ARMCX3 KIFAP3 DST CFAP69

3.24e-043171429GO:0032838
GeneOntologyCellularComponentextrinsic component of plasma membrane

ARSA GNA14 GNA11 GNAQ GNAS GNAZ

3.50e-041371426GO:0019897
GeneOntologyCellularComponentsecretory granule

SEMG1 SEMG2 CAB39 NPY1R ATG7 ABCA12 PRAMEF1 PRAMEF2 PRAMEF13 STK11IP CLEC12A ITPR1 ITPR2 ITPR3 ARSA PLA1A VPS13B

5.31e-04101414217GO:0030141
GeneOntologyCellularComponentaxoneme

DNAH3 DNAH10 ATG7 DYNC2H1 CNTRL KIFAP3 CFAP69

5.43e-042071427GO:0005930
GeneOntologyCellularComponentciliary plasm

DNAH3 DNAH10 ATG7 DYNC2H1 CNTRL KIFAP3 CFAP69

5.59e-042081427GO:0097014
GeneOntologyCellularComponentmotile cilium

DNAH3 PTCHD3 DNAH10 DYNC2H1 PRAMEF1 PRAMEF2 PRAMEF13 DNAH14 CFAP69

7.33e-043551429GO:0031514
GeneOntologyCellularComponentsecretory vesicle

SEMG1 SEMG2 CAB39 NPY1R ATG7 ABCA12 NTF3 PRAMEF1 PRAMEF2 PRAMEF13 STK11IP CLEC12A ITPR1 ITPR2 ITPR3 ARSA PLA1A ANP32E VPS13B

7.85e-04124614219GO:0099503
GeneOntologyCellularComponentcytoplasmic region

DNAH3 DNAH10 ATG7 DYNC2H1 CNTRL ARMCX3 KIFAP3 DST CFAP69

8.09e-043601429GO:0099568
GeneOntologyCellularComponentextrinsic component of membrane

ARSA GNA14 PIK3CA GNA11 GNAQ GNAS GNAZ

1.01e-032301427GO:0019898
GeneOntologyCellularComponentcytoplasmic side of plasma membrane

DST GNA14 GNA11 GNAQ GNAS GNAZ

1.68e-031851426GO:0009898
GeneOntologyCellularComponentinner dynein arm

DNAH3 DNAH10

1.99e-03101422GO:0036156
GeneOntologyCellularComponentsupramolecular fiber

CAB39 DNAH3 DNAH10 MYO6 DYNC2H1 DCTN2 NCKIPSD MYO18A HAUS3 DNAH14 SPAG5 TTLL7 KIFAP3 DST LRRC27 SCN5A MYBPC2

2.70e-03117914217GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

CAB39 DNAH3 DNAH10 MYO6 DYNC2H1 DCTN2 NCKIPSD MYO18A HAUS3 DNAH14 SPAG5 TTLL7 KIFAP3 DST LRRC27 SCN5A MYBPC2

2.90e-03118714217GO:0099081
GeneOntologyCellularComponentaxon

NPY1R ATG7 MYO6 DCTN2 NTF3 N4BP3 ARMCX3 ITPR2 SLIT2 DST SACS SCN5A KCNMA1 WDFY3

3.02e-0389114214GO:0030424
GeneOntologyCellularComponentmicrotubule

DNAH3 DNAH10 DYNC2H1 DCTN2 HAUS3 DNAH14 SPAG5 TTLL7 KIFAP3 DST

3.53e-0353314210GO:0005874
MousePhenoabnormal male germ cell apoptosis

CYP26B1 RAD21L1 PRAMEF1 PRAMEF2 PRAMEF13 ELMO1 RAD51AP2 ARSA PRAMEF14 VPS13B

1.95e-0523611210MP:0008280
MousePhenoabnormal male germ cell physiology

CYP26B1 RAD21L1 PRAMEF1 PRAMEF2 PRAMEF13 ELMO1 RAD51AP2 ARSA PRAMEF14 VPS13B

2.60e-0524411210MP:0020362
MousePhenoabnormal germ cell physiology

CYP26B1 RAD21L1 PRAMEF1 PRAMEF2 PRAMEF13 ELMO1 RAD51AP2 ARSA PRAMEF14 VPS13B

5.58e-0526711210MP:0020363
Domain-

CNTRL SLITRK4 KERA CPN2 PRAMEF1 PRAMEF2 SHOC2 PRAMEF13 STK11IP TLR10 SLIT2 LRRC27 ANP32E LRRC8B LRRD1

2.12e-08321141153.80.10.10
DomainL_dom-like

CNTRL SLITRK4 KERA CPN2 PRAMEF1 PRAMEF2 SHOC2 PRAMEF13 STK11IP TLR10 SLIT2 LRRC27 ANP32E LRRC8B LRRD1

2.82e-0832814115IPR032675
DomainLRR

CNTRL SLITRK4 KERA CPN2 SHOC2 STK11IP TLR10 SLIT2 LRRC27 ANP32E LRRC8B LRRD1

4.11e-0820114112PS51450
DomainARM-type_fold

CAB39 SMG1 RTTN ARFGEF1 IPO4 ARMCX3 ELMO1 ITPR1 ITPR2 KIFAP3 PIK3CA UTP20 WDFY3 CFAP69 XPO7

4.36e-0833914115IPR016024
DomainGproteinA_insert

GNA14 GNA11 GNAQ GNAS GNAZ

9.33e-08161415IPR011025
Domain-

GNA14 GNA11 GNAQ GNAS GNAZ

9.33e-081614151.10.400.10
DomainG-alpha

GNA14 GNA11 GNAQ GNAS GNAZ

9.33e-08161415PF00503
DomainG_alpha

GNA14 GNA11 GNAQ GNAS GNAZ

9.33e-08161415SM00275
DomainGprotein_alpha_su

GNA14 GNA11 GNAQ GNAS GNAZ

1.31e-07171415IPR001019
DomainPlexin_cytopl

PLXNA3 PLXNA1 PLXNA2 PLXNB1

3.81e-0791414PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA3 PLXNA1 PLXNA2 PLXNB1

3.81e-0791414IPR013548
DomainPlexin

PLXNA3 PLXNA1 PLXNA2 PLXNB1

3.81e-0791414IPR031148
DomainInsP3_rcpt-bd

ITPR1 ITPR2 ITPR3

4.21e-0731413IPR000493
DomainLRR_1

CNTRL SLITRK4 KERA CPN2 SHOC2 TLR10 SLIT2 LRRC27 ANP32E LRRC8B LRRD1

8.69e-0721914111PF00560
DomainLRR_TYP

CNTRL SLITRK4 KERA CPN2 SHOC2 TLR10 SLIT2 LRRC27 LRRC8B LRRD1

9.59e-0717714110SM00369
DomainLeu-rich_rpt_typical-subtyp

CNTRL SLITRK4 KERA CPN2 SHOC2 TLR10 SLIT2 LRRC27 LRRC8B LRRD1

9.59e-0717714110IPR003591
DomainARM-like

CAB39 SMG1 RTTN ARFGEF1 IPO4 ARMCX3 ELMO1 KIFAP3 UTP20 WDFY3 CFAP69 XPO7

9.95e-0727014112IPR011989
DomainLeu-rich_rpt

CNTRL SLITRK4 KERA CPN2 SHOC2 STK11IP TLR10 SLIT2 LRRC27 ANP32E LRRC8B LRRD1

1.03e-0627114112IPR001611
DomainGprotein_alpha_Q

GNA14 GNA11 GNAQ

1.68e-0641413IPR000654
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH10 DYNC2H1 DNAH14

2.94e-06141414IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH10 DYNC2H1 DNAH14

2.94e-06141414IPR024743
DomainMT

DNAH3 DNAH10 DYNC2H1 DNAH14

2.94e-06141414PF12777
DomainAAA_8

DNAH3 DNAH10 DYNC2H1 DNAH14

2.94e-06141414PF12780
DomainDHC_fam

DNAH3 DNAH10 DYNC2H1 DNAH14

3.98e-06151414IPR026983
DomainDynein_heavy

DNAH3 DNAH10 DYNC2H1 DNAH14

3.98e-06151414PF03028
DomainDynein_heavy_dom

DNAH3 DNAH10 DYNC2H1 DNAH14

3.98e-06151414IPR004273
DomainLRR_8

SLITRK4 KERA CPN2 SHOC2 TLR10 SLIT2 LRRC27 LRRC8B LRRD1

6.09e-061711419PF13855
Domain-

CAB39 RTTN ARFGEF1 IPO4 ARMCX3 ELMO1 KIFAP3 UTP20 WDFY3 CFAP69

7.31e-06222141101.25.10.10
DomainRIH_assoc-dom

ITPR1 ITPR2 ITPR3

8.29e-0661413IPR013662
DomainIns145_P3_rec

ITPR1 ITPR2 ITPR3

8.29e-0661413PF08709
DomainRIH_assoc

ITPR1 ITPR2 ITPR3

8.29e-0661413PF08454
DomainRIH_dom

ITPR1 ITPR2 ITPR3

8.29e-0661413IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2 ITPR3

8.29e-0661413IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2 ITPR3

8.29e-0661413IPR015925
Domain-

ITPR1 ITPR2 ITPR3

8.29e-06614131.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2 ITPR3

8.29e-0661413PF01365
Domain-

DNAH3 SAMD9 DNAH10 ABCA12 DYNC2H1 MYO18A ABCC6 DNAH14 TRANK1 GNA14 ATAD1 ABCA6 HFM1 GNA11 GNAQ GNAS ABCC2 GNAZ

1.33e-05746141183.40.50.300
DomainAAA

DNAH3 DNAH10 ABCA12 DYNC2H1 ABCC6 ATAD1 ABCA6 ABCC2

1.37e-051441418SM00382
DomainAAA+_ATPase

DNAH3 DNAH10 ABCA12 DYNC2H1 ABCC6 ATAD1 ABCA6 ABCC2

1.37e-051441418IPR003593
DomainP-loop_NTPase

DNAH3 SAMD9 DNAH10 MYO6 ABCA12 DYNC2H1 MYO18A ABCC6 DNAH14 TRANK1 GNA14 ATAD1 ABCA6 HFM1 GNA11 GNAQ GNAS ABCC2 GNAZ

2.12e-0584814119IPR027417
DomainIPT

PLXNA3 PLXNA1 PLXNA2 PLXNB1

4.77e-05271414SM00429
DomainMIR

ITPR1 ITPR2 ITPR3

4.86e-05101413PF02815
DomainMIR_motif

ITPR1 ITPR2 ITPR3

4.86e-05101413IPR016093
DomainMIR

ITPR1 ITPR2 ITPR3

4.86e-05101413PS50919
DomainMIR

ITPR1 ITPR2 ITPR3

4.86e-05101413SM00472
DomainRho_GTPase_activation_prot

PLXNA3 IQGAP3 PLXNA1 PLXNA2 PLXNB1 ARHGAP19

5.42e-05881416IPR008936
DomainTMEM131-like

TMEM131L TMEM131

5.66e-0521412IPR022113
DomainTMEM131_like

TMEM131L TMEM131

5.66e-0521412PF12371
DomainSemenogelin

SEMG1 SEMG2

5.66e-0521412PF05474
DomainSemenogelin

SEMG1 SEMG2

5.66e-0521412IPR008836
DomainSemap_dom

PLXNA3 PLXNA1 PLXNA2 PLXNB1

8.36e-05311414IPR001627
DomainSEMA

PLXNA3 PLXNA1 PLXNA2 PLXNB1

8.36e-05311414PS51004
DomainTIG

PLXNA3 PLXNA1 PLXNA2 PLXNB1

8.36e-05311414PF01833
DomainSema

PLXNA3 PLXNA1 PLXNA2 PLXNB1

8.36e-05311414SM00630
DomainSema

PLXNA3 PLXNA1 PLXNA2 PLXNB1

8.36e-05311414PF01403
DomainIPT

PLXNA3 PLXNA1 PLXNA2 PLXNB1

9.50e-05321414IPR002909
DomainPlexin_repeat

PLXNA3 PLXNA1 PLXNA2 PLXNB1

9.50e-05321414IPR002165
DomainPSI

PLXNA3 PLXNA1 PLXNA2 PLXNB1

9.50e-05321414PF01437
DomainDynein_heavy_dom-2

DNAH3 DNAH10 DYNC2H1

1.44e-04141413IPR013602
DomainDHC_N2

DNAH3 DNAH10 DYNC2H1

1.44e-04141413PF08393
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH10 DYNC2H1

1.44e-04141413IPR011704
DomainAAA_5

DNAH3 DNAH10 DYNC2H1

1.44e-04141413PF07728
DomainRasGAP_dom

PLXNA3 IQGAP3 PLXNB1

3.16e-04181413IPR001936
DomainPSI

PLXNA3 PLXNA1 PLXNA2 PLXNB1

3.34e-04441414IPR016201
DomainMultidrug-R_assoc

ABCC6 ABCC2

3.36e-0441412IPR005292
DomainPRAME_family

PRAMEF1 PRAMEF2 PRAMEF13

3.74e-04191413IPR026271
DomainPSI

PLXNA3 PLXNA1 PLXNA2 PLXNB1

3.97e-04461414SM00423
DomainABC_tran

ABCA12 ABCC6 ABCA6 ABCC2

4.68e-04481414PF00005
DomainABC_TRANSPORTER_2

ABCA12 ABCC6 ABCA6 ABCC2

4.68e-04481414PS50893
DomainABC_TRANSPORTER_1

ABCA12 ABCC6 ABCA6 ABCC2

5.07e-04491414PS00211
DomainABC_transporter-like

ABCA12 ABCC6 ABCA6 ABCC2

5.48e-04501414IPR003439
DomainLRRNT

SLITRK4 KERA CPN2 SLIT2

6.84e-04531414PF01462
DomainDHC_N1

DNAH10 DYNC2H1

1.54e-0381412PF08385
DomainDynein_heavy_dom-1

DNAH10 DYNC2H1

1.54e-0381412IPR013594
DomainTPR_REGION

ST13P4 SPAG1 DNAH10 ZFC3H1 TRANK1 TTC7B

1.59e-031651416PS50293
DomainTPR

ST13P4 SPAG1 DNAH10 ZFC3H1 TRANK1 TTC7B

1.59e-031651416PS50005
DomainIon_trans_dom

ITPR1 ITPR2 ITPR3 SCN5A KCNMA1

1.74e-031141415IPR005821
DomainIon_trans

ITPR1 ITPR2 ITPR3 SCN5A KCNMA1

1.74e-031141415PF00520
DomainNPY_rcpt

NPY1R PROKR1

1.97e-0391412IPR000611
DomainTPR-like_helical_dom

ST13P4 SPAG1 SAMD9 ZFC3H1 ZHX1-C8orf76 TRANK1 TTC7B

1.98e-032331417IPR011990
DomainIQ

MYO6 MYO18A SCN5A IQGAP3

3.30e-03811414SM00015
DomainABC_A

ABCA12 ABCA6

3.55e-03121412IPR026082
DomainABC_transporter_CS

ABCA12 ABCC6 ABCC2

3.90e-03421413IPR017871
DomainCys-rich_flank_reg_C

SLITRK4 CPN2 TLR10 SLIT2

4.82e-03901414IPR000483
DomainLRRCT

SLITRK4 CPN2 TLR10 SLIT2

4.82e-03901414SM00082
DomainIQ_motif_EF-hand-BS

MYO6 MYO18A SCN5A IQGAP3

4.82e-03901414IPR000048
DomainIMPORTIN_B_NT

IPO4 XPO7

4.85e-03141412PS50166
DomainIQ

MYO6 MYO18A SCN5A IQGAP3

5.41e-03931414PS50096
DomainPI3/4_kinase_CS

SMG1 PIK3CA

5.57e-03151412IPR018936
DomainIBN_N

IPO4 XPO7

5.57e-03151412PF03810
DomainTPR-contain_dom

ST13P4 SPAG1 ZFC3H1 TRANK1 TTC7B

5.64e-031501415IPR013026
Domain-

SMG1 PIK3CA

6.34e-031614121.10.1070.11
DomainIBN_N

IPO4 XPO7

6.34e-03161412SM00913
DomainPI3Kc

SMG1 PIK3CA

6.34e-03161412SM00146
Domain-

PLXNA3 IQGAP3

6.34e-031614121.10.506.10
DomainLRRNT

SLITRK4 KERA CPN2 SLIT2

6.50e-03981414IPR000372
DomainLRRNT

SLITRK4 KERA CPN2 SLIT2

6.50e-03981414SM00013
DomainImportin-beta_N

IPO4 XPO7

7.15e-03171412IPR001494
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ GNAS

3.05e-07611047MM15071
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 GNAQ

5.67e-07101044M47661
PathwayKEGG_LONG_TERM_DEPRESSION

ITPR1 ITPR2 ITPR3 GNA11 GNAQ GNAS GNAZ

7.94e-07701047M8232
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 GNAQ

8.87e-07111044M49033
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ GNAS

9.64e-07721047MM14631
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ GNAS

1.67e-06781047M1921
PathwayKEGG_MEDICUS_REFERENCE_GPCR_PLCB_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ

1.70e-06501046M47951
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 GNAQ

1.90e-06131044M47656
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ

2.70e-06541046M26911
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.86e-0651043M49000
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

7.68e-0661043M47960
PathwayPID_ER_NONGENOMIC_PATHWAY

GNA14 PIK3CA GNA11 GNAQ GNAZ

1.06e-05401045M41
PathwayKEGG_MEDICUS_REFERENCE_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 GNAQ

1.24e-05201044M47688
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ GNAS

1.47e-051081047M17034
PathwayPID_S1P_META_PATHWAY

GNA14 GNA11 GNAQ GNAZ

1.52e-05211044M155
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MACHR_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 GNAQ

1.52e-05211044M47689
PathwayPID_THROMBIN_PAR1_PATHWAY

GNA14 PIK3CA GNA11 GNAQ GNAZ

1.53e-05431045M238
PathwayWP_RENINANGIOTENSINALDOSTERONE_SYSTEM_RAAS

ITPR1 ITPR2 ITPR3 GNAQ CREB3L3

1.71e-05441045M39845
PathwayWP_PKCGAMMA_CALCIUM_SIGNALING_IN_ATAXIA

ITPR1 GNA14 GNA11 GNAQ

1.85e-05221044M39795
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 GNAQ

1.85e-05221044M47690
PathwayKEGG_MEDICUS_REFERENCE_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 GNAQ

1.85e-05221044M47675
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

NPY1R SUCNR1 ITPR1 ITPR2 ITPR3 GNA14 GNA11 CCR5 GNAQ GNAS GNAZ

1.99e-0531410411M600
PathwayREACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION

GNA14 GNA11 GNAQ

2.13e-0581043MM15032
PathwayREACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION

GNA14 GNA11 GNAQ

2.13e-0581043M27356
PathwayREACTOME_FATTY_ACIDS_BOUND_TO_GPR40_FFAR1_REGULATE_INSULIN_SECRETION

GNA14 GNA11 GNAQ

2.13e-0581043MM15100
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

ITPR1 ITPR2 ITPR3 KCNMA1 GNA11 GNAQ GNAS

2.21e-051151047M9387
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3 GNAQ

2.22e-05231044M47676
PathwayPID_S1P_S1P2_PATHWAY

GNA14 GNA11 GNAQ GNAZ

2.65e-05241044M268
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA1 PLXNA2

3.17e-0591043MM15030
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.17e-0591043M47852
PathwayREACTOME_ACETYLCHOLINE_REGULATES_INSULIN_SECRETION

GNA14 GNA11 GNAQ

4.51e-05101043M1825
PathwayREACTOME_OPIOID_SIGNALLING

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ

5.26e-05901046M6467
PathwayKEGG_GAP_JUNCTION

ITPR1 ITPR2 ITPR3 GNA11 GNAQ GNAS

5.26e-05901046M4013
PathwayWP_G_PROTEIN_SIGNALING_PATHWAYS

ITPR1 GNA14 GNA11 GNAQ GNAS GNAZ

5.26e-05901046MM15882
PathwayWP_G_PROTEIN_SIGNALING

ITPR1 GNA14 GNA11 GNAQ GNAS GNAZ

5.60e-05911046M39426
PathwayPID_S1P_S1P3_PATHWAY

GNA14 GNA11 GNAQ GNAZ

5.76e-05291044M55
PathwayREACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION

GNA14 GNA11 GNAQ

6.17e-05111043M27317
PathwayREACTOME_FREE_FATTY_ACIDS_REGULATE_INSULIN_SECRETION

GNA14 GNA11 GNAQ

6.17e-05111043MM15035
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2 ITPR3

6.17e-05111043M27466
PathwayREACTOME_SIGNALING_BY_GPCR

NPY1R MC2R SUCNR1 ITPR1 ITPR2 ITPR3 PROKR1 GNA14 PIK3CA GNA11 CCR5 GNAQ GNAS GNAZ PLXNB1

7.56e-0564610415MM14962
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3 GNAS

8.58e-05321044MM14983
PathwayKEGG_GNRH_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 GNA11 GNAQ GNAS

1.00e-041011046M1979
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.06e-04131043M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

1.06e-04131043M47751
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

1.06e-04131043MM14553
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

ITPR1 ITPR2 ITPR3 GNA11 GNAQ GNAS GNAZ

1.06e-041471047MM15854
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

ITPR1 ITPR2 ITPR3 GNA11 GNAQ GNAS GNAZ

1.26e-041511047M39329
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PLXNA1 PLXNA2

1.34e-04141043MM15029
PathwayREACTOME_SEMA3A_PLEXIN_REPULSION_SIGNALING_BY_INHIBITING_INTEGRIN_ADHESION

PLXNA3 PLXNA1 PLXNA2

1.34e-04141043M7578
PathwaySIG_PIP3_SIGNALING_IN_B_LYMPHOCYTES

ITPR1 ITPR2 ITPR3 PIK3CA

1.37e-04361044M1315
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

ITPR1 ITPR2 ITPR3 PROKR1 GNA14 PIK3CA GNA11 GNAQ

1.61e-042101048MM15043
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA3 PLXNA1 PLXNA2

1.66e-04151043MM15031
PathwayPID_THROMBIN_PAR4_PATHWAY

GNA14 GNA11 GNAQ

1.66e-04151043M138
PathwayREACTOME_SIGNALING_BY_GPCR

NPY1R MC2R SUCNR1 ITPR1 ITPR2 ITPR3 PROKR1 GNA14 PIK3CA GNA11 CCR5 GNAQ GNAS GNAZ PLXNB1

1.90e-0470210415M746
PathwayREACTOME_G_ALPHA_Q_SIGNALLING_EVENTS

ITPR1 ITPR2 ITPR3 PROKR1 GNA14 PIK3CA GNA11 GNAQ

2.01e-042171048M18437
PathwayREACTOME_SEMA3A_PAK_DEPENDENT_AXON_REPULSION

PLXNA3 PLXNA1 PLXNA2

2.04e-04161043M16498
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2 ITPR3

2.04e-04161043M26945
PathwayREACTOME_CRMPS_IN_SEMA3A_SIGNALING

PLXNA3 PLXNA1 PLXNA2

2.04e-04161043M8245
PathwayREACTOME_GLUCAGON_LIKE_PEPTIDE_1_GLP1_REGULATES_INSULIN_SECRETION

ITPR1 ITPR2 ITPR3 GNAS

2.52e-04421044M791
PathwayREACTOME_SIGNALING_BY_CYTOSOLIC_FGFR1_FUSION_MUTANTS

CNTRL MYO18A PIK3CA

2.94e-04181043M673
PathwayKEGG_ABC_TRANSPORTERS

ABCA12 ABCC6 ABCA6 ABCC2

3.02e-04441044M11911
PathwayWP_VASOPRESSINREGULATED_WATER_REABSORPTION

DYNC2H1 DCTN2 CREB3L3 GNAS

3.02e-04441044M42554
PathwayKEGG_VASOPRESSIN_REGULATED_WATER_REABSORPTION

DYNC2H1 DCTN2 CREB3L3 GNAS

3.02e-04441044M9011
PathwaySIG_CHEMOTAXIS

ITPR1 ITPR2 ITPR3 PIK3CA

3.30e-04451044M5193
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ GNAS

3.45e-041781047M2890
PathwayREACTOME_VEGFR2_MEDIATED_CELL_PROLIFERATION

ITPR1 ITPR2 ITPR3

3.47e-04191043M27423
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 ITPR3

3.47e-04191043M47760
PathwayKEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3

3.47e-04191043M47733
PathwaySIG_BCR_SIGNALING_PATHWAY

ITPR1 ITPR2 ITPR3 PIK3CA

3.60e-04461044M8626
PathwayREACTOME_RHO_GTPASE_CYCLE

ARHGEF28 KCTD13 MYO6 KTN1 ARMCX3 DST PIK3CA IQGAP3 PLXNA1 PLXNB1 ARHGAP19

3.89e-0443910411MM15595
PathwayREACTOME_PLATELET_HOMEOSTASIS

ITPR1 ITPR2 ITPR3 KCNMA1 GNAS

4.30e-04861045M916
PathwayREACTOME_RHO_GTPASE_CYCLE

ARHGEF28 KCTD13 MYO6 KTN1 ARMCX3 DST PIK3CA IQGAP3 PLXNA1 PLXNB1 ARHGAP19

4.79e-0445010411M27078
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

PLXNA3 PLXNA1 PLXNA2 PLXNB1

5.35e-04511044MM14967
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

CYP26B1 RDH13 DHRS9

5.42e-04221043M27445
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

NCKIPSD ELMO1 ITPR1 ITPR2 ITPR3 PIK3CA

6.59e-041431046M27107
PathwayREACTOME_G_PROTEIN_ACTIVATION

GNA14 GNA11 GNAQ

7.05e-04241043M13115
PathwayREACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR

GNA14 GNA11 GNAQ

7.05e-04241043MM15088
PathwayREACTOME_THROMBOXANE_SIGNALLING_THROUGH_TP_RECEPTOR

GNA14 GNA11 GNAQ

7.05e-04241043M18308
PathwayREACTOME_G_PROTEIN_ACTIVATION

GNA14 GNA11 GNAQ

7.05e-04241043MM14794
PathwayKEGG_MEDICUS_PATHOGEN_HCMV_UL33_TO_GNAQ_PLCB_G_CALCINEURIN_SIGNALING_PATHWAY

GNA11 GNAQ

7.93e-0461042M47548
PathwayREACTOME_ACTIVATED_NTRK3_SIGNALS_THROUGH_PI3K

NTF3 PIK3CA

7.93e-0461042M27929
PathwayREACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1

GNA14 GNA11 GNAQ

7.97e-04251043MM15056
PathwayREACTOME_ADP_SIGNALLING_THROUGH_P2Y_PURINOCEPTOR_1

GNA14 GNA11 GNAQ

7.97e-04251043M811
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 ITPR3

7.97e-04251043MM14511
PathwayREACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3

ARHGEF28 KCTD13 MYO6 KTN1 NCKIPSD NUF2 ARMCX3 DST PIK3CA IQGAP3 PLXNA1 PLXNB1 ARHGAP19

9.56e-0464910413MM15690
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

1.00e-03271043MM15053
PathwayREACTOME_EFFECTS_OF_PIP2_HYDROLYSIS

ITPR1 ITPR2 ITPR3

1.00e-03271043M12123
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SOD1_TO_RETROGRADE_AXONAL_TRANSPORT

DNAH3 DNAH10 DCTN2

1.00e-03271043M47755
PathwayREACTOME_SIGNALING_BY_VEGF

ELMO1 ITPR1 ITPR2 ITPR3 PIK3CA

1.11e-031061045M27077
PathwayREACTOME_RA_BIOSYNTHESIS_PATHWAY

CYP26B1 RDH13 DHRS9

1.12e-03281043MM15188
PathwayREACTOME_PLATELET_CALCIUM_HOMEOSTASIS

ITPR1 ITPR2 ITPR3

1.12e-03281043M924
PathwayREACTOME_LEISHMANIA_INFECTION

NCKIPSD ELMO1 ITPR1 ITPR2 ITPR3 GNAS GNAZ

1.18e-032191047M29836
PathwayPID_ENDOTHELIN_PATHWAY

GNA14 GNA11 GNAQ GNAZ

1.19e-03631044M8
PathwayREACTOME_SEMAPHORIN_INTERACTIONS

PLXNA3 PLXNA1 PLXNA2 PLXNB1

1.26e-03641044M7923
PathwayPID_LYSOPHOSPHOLIPID_PATHWAY

GNA14 GNA11 GNAQ GNAZ

1.34e-03651044M15
PathwayWP_GPR143_IN_MELANOCYTES_AND_RETINAL_PIGMENT_EPITHELIUM_CELLS

ITPR1 GNAQ GNAS

1.37e-03301043M42578
PathwayREACTOME_FGFR1_MUTANT_RECEPTOR_ACTIVATION

CNTRL MYO18A PIK3CA

1.51e-03311043M661
PathwayKEGG_MEDICUS_VARIANT_CYP11B1_CYP11B2_FUSION_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

MC2R CREB3L3 GNAS

1.51e-03311043M47507
PathwayREACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS

GNA14 GNA11 GNAQ

1.66e-03321043M861
PathwayREACTOME_THROMBIN_SIGNALLING_THROUGH_PROTEINASE_ACTIVATED_RECEPTORS_PARS

GNA14 GNA11 GNAQ

1.66e-03321043MM15148
Pubmed

Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle.

ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ

2.30e-1115145628578927
Pubmed

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

2.90e-10414548570614
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

2.00e-088145415661641
Pubmed

The role of neuropilins in cell signalling.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

3.59e-089145419909241
Pubmed

Analysis of G protein alpha subunit mRNA abundance in preimplantation mouse embryos using a rapid, quantitative RT-PCR approach.

GNA14 GNA11 GNAQ GNAS

5.97e-081014548588930
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2 ITPR3

7.10e-083145310874040
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2 ITPR3

7.10e-083145320395455
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2 ITPR3

7.10e-083145317437169
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2 ITPR3

7.10e-083145318547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2 ITPR3

7.10e-083145336350267
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2 ITPR3

7.10e-083145311413485
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

7.10e-083145326009177
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2 ITPR3

7.10e-08314531693919
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2 ITPR3

7.10e-083145323955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2 ITPR3

7.10e-083145331979185
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2 ITPR3

7.10e-083145324904548
Pubmed

High frequency of GNA14, GNAQ, and GNA11 mutations in cherry hemangioma: a histopathological and molecular study of 85 cases indicating GNA14 as the most commonly mutated gene in vascular neoplasms.

GNA14 GNA11 GNAQ

7.10e-083145331189994
Pubmed

Differential distribution of inositol trisphosphate receptor isoforms in mouse oocytes.

ITPR1 ITPR2 ITPR3

7.10e-08314539858485
Pubmed

G(q/11)α and G(s)α mediate distinct physiological responses to central melanocortins.

GNA11 GNAQ GNAS

7.10e-083145326595811
Pubmed

Expression of inositol 1,4,5-trisphosphate receptors in mouse oocytes and early embryos: the type I isoform is upregulated in oocytes and downregulated after fertilization.

ITPR1 ITPR2 ITPR3

7.10e-08314539808793
Pubmed

Identification of plexin family molecules in mice.

PLXNA3 PLXNA1 PLXNA2

7.10e-08314538806646
Pubmed

Gqα/G11α deficiency in dorsomedial hypothalamus leads to obesity resulting from decreased energy expenditure and impaired sympathetic nerve activity.

GNA11 GNAQ GNAS

7.10e-083145333166186
Pubmed

Type 2 and type 3 inositol 1,4,5-trisphosphate (IP3) receptors promote the differentiation of granule cell precursors in the postnatal cerebellum.

ITPR1 ITPR2 ITPR3

7.10e-083145318194433
Pubmed

IP3 receptors regulate vascular smooth muscle contractility and hypertension.

ITPR1 ITPR2 ITPR3

7.10e-083145327777977
Pubmed

Differential expression of plexin-A subfamily members in the mouse nervous system.

PLXNA3 PLXNA1 PLXNA2

7.10e-083145311241833
Pubmed

Differential inositol 1,4,5-trisphosphate receptor signaling in a neuronal cell line.

ITPR1 ITPR2 ITPR3

7.10e-083145317581770
Pubmed

Predominant role of type 1 IP3 receptor in aortic vascular muscle contraction.

ITPR1 ITPR2 ITPR3

7.10e-083145318241669
Pubmed

Granulosa cells express three inositol 1,4,5-trisphosphate receptor isoforms: cytoplasmic and nuclear Ca2+ mobilization.

ITPR1 ITPR2 ITPR3

7.10e-083145319068129
Pubmed

Molecular basis of the isoform-specific ligand-binding affinity of inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

7.10e-083145317327232
Pubmed

Nuclear inositol 1,4,5-trisphosphate receptors regulate local Ca2+ transients and modulate cAMP response element binding protein phosphorylation.

ITPR1 ITPR2 ITPR3

7.10e-083145316014380
Pubmed

Knockdown of the type 2 and 3 inositol 1,4,5-trisphosphate receptors suppresses muscarinic antinociception in mice.

ITPR1 ITPR2 ITPR3

7.10e-083145317890015
Pubmed

GNAS, GNAQ, and GNA11 alterations in patients with diverse cancers.

GNA11 GNAQ GNAS

7.10e-083145330204251
Pubmed

Inositol 1, 4, 5-trisphosphate receptors and human left ventricular myocytes.

ITPR1 ITPR2 ITPR3

7.10e-083145323983250
Pubmed

Activation of the inositol (1,4,5)-triphosphate calcium gate receptor is required for HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

7.10e-083145320427533
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

PLXNA3 SLIT2 PLXNA1 PLXNA2 PLXNB1

1.07e-0728145518617019
Pubmed

G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development.

GNA14 GNA11 GNAQ GNAS GNAZ

1.07e-072814558858601
Pubmed

Diversity of the G-protein family: sequences from five additional alpha subunits in the mouse.

GNA14 GNA11 GNAS GNAZ

1.40e-071214542508088
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

1.40e-0712145421270798
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

2.01e-0713145410520995
Pubmed

Loss of IP3R-dependent Ca2+ signalling in thymocytes leads to aberrant development and acute lymphoblastic leukemia.

ITPR1 ITPR2 ITPR3

2.83e-074145325215520
Pubmed

Promiscuous coupling of receptors to Gq class alpha subunits and effector proteins in pancreatic and submandibular gland cells.

GNA14 GNA11 GNAQ

2.83e-07414539765251
Pubmed

Chromosome assignment of four plexin A genes (Plxna1, Plxna2, Plxna3, Plxna4) in mouse, rat, Syrian hamster and Chinese hamster.

PLXNA3 PLXNA1 PLXNA2

2.83e-074145311306810
Pubmed

PlexinA polymorphisms mediate the developmental trajectory of human corpus callosum microstructure.

PLXNA3 PLXNA1 PLXNA2

2.83e-074145325518740
Pubmed

Deletion of Gαq/11 or Gαs Proteins in Gonadotropes Differentially Affects Gonadotropin Production and Secretion in Mice.

GNA11 GNAQ GNAS

2.83e-074145334864945
Pubmed

Determination of cell adhesion sites of neuropilin-1.

PLXNA3 PLXNA1 PLXNA2

2.83e-074145310725340
Pubmed

Alternative splice variants of hTrp4 differentially interact with the C-terminal portion of the inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2 ITPR3

2.83e-074145311163362
Pubmed

Stabilization of cortical actin induces internalization of transient receptor potential 3 (Trp3)-associated caveolar Ca2+ signaling complex and loss of Ca2+ influx without disruption of Trp3-inositol trisphosphate receptor association.

ITPR1 ITPR3 GNA11

2.83e-074145311524429
Pubmed

Inositol 1, 4, 5-trisphosphate receptor interacts with the SNARE domain of syntaxin 1B.

ITPR1 ITPR2 ITPR3

2.83e-074145321424589
Pubmed

Embryonic cardiomyocyte hypoplasia and craniofacial defects in G alpha q/G alpha 11-mutant mice.

GNA14 GNA11 GNAQ

2.83e-07414539687499
Pubmed

Loss of IP3 Receptor-Mediated Ca2+ Release in Mouse B Cells Results in Abnormal B Cell Development and Function.

ITPR1 ITPR2 ITPR3

2.83e-074145328615414
Pubmed

Distinct localization and function of (1,4,5)IP(3) receptor subtypes and the (1,3,4,5)IP(4) receptor GAP1(IP4BP) in highly purified human platelet membranes.

ITPR1 ITPR2 ITPR3

2.83e-074145310828023
Pubmed

IP3R-mediated Ca2+ signals govern hematopoietic and cardiac divergence of Flk1+ cells via the calcineurin-NFATc3-Etv2 pathway.

ITPR1 ITPR2 ITPR3

2.83e-074145328419336
Pubmed

IP3R-mediated Ca2+ signaling controls B cell proliferation through metabolic reprogramming.

ITPR1 ITPR2 ITPR3

2.83e-074145335494252
Pubmed

Cloning and characterization of the human phosphoinositide-specific phospholipase C-beta 1 (PLC beta 1).

GNA14 GNA11 GNAQ GNAZ

3.82e-0715145411118617
Pubmed

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

5.07e-0716145417356169
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

6.61e-0717145411683995
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

6.61e-0717145417626059
Pubmed

Receptor Activity-modifying Protein-directed G Protein Signaling Specificity for the Calcitonin Gene-related Peptide Family of Receptors.

GNA11 GNAQ GNAS

7.05e-075145327566546
Pubmed

Semaphorin 5A inhibits synaptogenesis in early postnatal- and adult-born hippocampal dentate granule cells.

PLXNA3 PLXNA1 PLXNA2

7.05e-075145325313870
Pubmed

Loss of gq/11 genes does not abolish melanopsin phototransduction.

GNA14 GNA11 GNAQ

7.05e-075145324870805
Pubmed

An Acetate-Specific GPCR, FFAR2, Regulates Insulin Secretion.

ITPR1 GNA11 GNAQ

7.05e-075145326075576
Pubmed

Protein kinase A-mediated phosphorylation of serine 357 of the mouse prostacyclin receptor regulates its coupling to G(s)-, to G(i)-, and to G(q)-coupled effector signaling.

GNA11 GNAQ GNAS

7.05e-075145311443126
Pubmed

InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.

ITPR1 ITPR2 ITPR3

7.05e-075145321568942
Pubmed

The heterotrimeric G protein subunits Gα(q) and Gβ(1) have lysophospholipase D activity.

GNA11 GNAQ GNAS

7.05e-075145321812758
Pubmed

The promoter of the oocyte-specific gene, Oog1, functions in both male and female meiotic germ cells in transgenic mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

8.48e-0718145423894331
Pubmed

Oogenesin is a novel mouse protein expressed in oocytes and early cleavage-stage embryos.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

8.48e-0718145412890732
Pubmed

Oocyte-specific gene Oog1 suppresses the expression of spermatogenesis-specific genes in oocytes.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

8.48e-0718145429731491
Pubmed

Identification of a new expanding family of genes characterized by atypical LRR domains. Localization of a cluster preferentially expressed in oocyte.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

8.48e-0718145414675769
Pubmed

Pramel7 mediates ground-state pluripotency through proteasomal-epigenetic combined pathways.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.07e-0619145428604677
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

DNAH10 DYNC2H1 RTTN MYO18A ZFC3H1 DST SCN5A PLXNA1

1.28e-06187145826460568
Pubmed

Preferentially Expressed Antigen in Melanoma (PRAME) and the PRAME Family of Leucine-Rich Repeat Proteins.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.33e-0620145426694250
Pubmed

Oog1, an oocyte-specific protein, interacts with Ras and Ras-signaling proteins during early embryogenesis.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.33e-0620145416580637
Pubmed

Pramel7 mediates LIF/STAT3-dependent self-renewal in embryonic stem cells.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

1.33e-0620145421425410
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

ITPR1 ITPR2 ITPR3

1.41e-066145323463619
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

ITPR1 ITPR2 ITPR3

1.41e-066145325966694
Pubmed

Expression and function of semaphorin 3A and its receptors in human monocyte-derived macrophages.

PLXNA3 PLXNA1 PLXNA2

1.41e-066145319480842
Pubmed

D1-D2 dopamine receptor heterooligomers with unique pharmacology are coupled to rapid activation of Gq/11 in the striatum.

GNA11 GNAQ GNAS

1.41e-066145317194762
Pubmed

Sprouty2 regulates PI(4,5)P2/Ca2+ signaling and HIV-1 Gag release.

ITPR1 ITPR2 ITPR3

1.41e-066145321762810
Pubmed

Using siRNA to define functional interactions between melanopsin and multiple G Protein partners.

GNA14 GNA11 GNAQ

1.41e-066145324958088
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

ITPR1 ITPR2 ITPR3

1.41e-066145320519450
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

ITPR1 ITPR2 ITPR3

1.41e-066145316844763
Pubmed

C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.

KTN1 ARFGEF1 STK11IP ARMCX3 ITPR1 ITPR2 ITPR3 DST TMEM131L TMEM131 PLXNA1 VPS13B

1.49e-065041451234432599
Pubmed

TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.

PLXNA3 SLIT2 PLXNA1 PLXNA2 PLXNB1

1.57e-0647145535462405
Pubmed

Evolution of the mammalian G protein alpha subunit multigene family.

GNA14 GNA11 GNAQ GNAS GNAZ

1.93e-064914551302014
Pubmed

Sertoli cell-only phenotype and scRNA-seq define PRAMEF12 as a factor essential for spermatogenesis in mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.00e-0622145431729367
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCA12 ABCC6 ABCA6 ABCC2

2.00e-062214548894702
Pubmed

Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

2.41e-0623145419480014
Pubmed

Semaphorin-6A controls guidance of corticospinal tract axons at multiple choice points.

PLXNA3 PLXNA1 PLXNA2

2.45e-067145319063725
Pubmed

Increased proximal bifurcation of CA1 pyramidal apical dendrites in sema3A mutant mice.

PLXNA3 PLXNA1 PLXNA2

2.45e-067145319655386
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

ITPR1 ITPR2 ITPR3

2.45e-067145311860456
Pubmed

Inositol-1,4,5-trisphosphate receptor regulates hepatic gluconeogenesis in fasting and diabetes.

ITPR1 ITPR2 ITPR3

2.45e-067145322495310
Pubmed

Plexin-neuropilin-1 complexes form functional semaphorin-3A receptors.

PLXNA3 PLXNA1 PLXNA2

2.45e-067145310520994
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

PLXNA3 DPY19L3 MAN2A1 KTN1 SLITRK4 ARFGEF1 NEK9 SPAG5 ITPR1 ITPR2 MGAT5 ARSA TMEM131L UTP20 TMEM131 USP48 PLXNA1 PLXNB1

2.86e-0612011451835696571
Pubmed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

PLXNA3 PLXNA1 PLXNA2 PLXNB1

2.89e-0624145428893946
Pubmed

Incomplete reactivation of Oct4-related genes in mouse embryos cloned from somatic nuclei.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

3.42e-0625145412620990
Pubmed

MAGE-B4, a binding partner of PRAMEF12, is dispensable for spermatogenesis and male fertility in mice.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

3.42e-0625145437451217
Pubmed

Integration of opposing semaphorin guidance cues in cortical axons.

PLXNA3 PLXNA1 PLXNA2

3.91e-068145322368082
Pubmed

Expression profiling in transgenic FVB/N embryonic stem cells overexpressing STAT3.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

4.03e-0626145418500982
Pubmed

Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

5.49e-0628145425089626
Pubmed

Protease-activated receptors in hemostasis, thrombosis and vascular biology.

GNA14 GNA11 GNAQ

5.85e-069145316102047
InteractionRHOA interactions

CNKSR1 ARHGEF28 KCTD13 MYO6 KTN1 SLITRK4 MYO18A IPO4 STK11IP ARMCX3 ITPR1 ITPR2 ITPR3 ATAD1 UTP20 GNA11 GNAS USP48 IQGAP3 PLXNA1 VPS13B PLXNB1 PMAIP1 ARHGAP19

3.29e-06119914224int:RHOA
InteractionRIC8A interactions

ATG7 DCTN2 SPAG5 GNA11 GNAQ GNAS GNAZ

5.25e-06961427int:RIC8A
InteractionCAPZA2 interactions

KCTD13 MYO6 DCTN2 KTN1 NCKIPSD MYO18A N4BP3 ITPR1 ITPR2 ITPR3 DST NUDCD1 USP48

1.14e-0543014213int:CAPZA2
InteractionSEMA5A interactions

PLXNA3 PLXNA1 PLXNA2

1.17e-0571423int:SEMA5A
InteractionTPPP interactions

SEMG1 SEMG2 KCTD13 SHOC2 USP48

1.96e-05471425int:TPPP
InteractionGNG3 interactions

GNA11 GNAQ GNAS GNAZ

2.25e-05241424int:GNG3
InteractionGNGT1 interactions

GNA11 GNAQ GNAS GNAZ

3.13e-05261424int:GNGT1
InteractionGNAO1 interactions

KCTD13 DCTN2 KIFAP3 GNA11 CCR5 GNAQ USP48

4.21e-051321427int:GNAO1
InteractionTAFA4 interactions

ITPR1 ITPR2 ITPR3 PLXNA1 PLXNA2

4.24e-05551425int:TAFA4
InteractionGNAQ interactions

KCTD13 KIFAP3 PIK3CA GNA11 CCR5 GNAQ GNAS

4.86e-051351427int:GNAQ
InteractionCNPY3 interactions

MAN2A1 SLITRK4 ALG2 ITPR1 ITPR2 TLR10 ARSA PLA1A

7.66e-051961428int:CNPY3
InteractionISG20 interactions

GNAQ GNAZ PLXNB1

9.30e-05131423int:ISG20
InteractionSCGB2A1 interactions

PLXNA3 MAN2A1 RDH13 MGAT5 PIK3CA WDFY3

9.48e-051041426int:SCGB2A1
InteractionCCDC22 interactions

PLXNA3 ATG7 DCTN2 SPAG5 ARSA COMMD4 XPO7

1.03e-041521427int:CCDC22
InteractionIRAG1 interactions

ITPR1 ITPR2 ITPR3

1.18e-04141423int:IRAG1
InteractionDEFA5 interactions

RDH13 PIK3CA PLXNA1 PLXNA2 ARHGAP19

1.36e-04701425int:DEFA5
InteractionFIBIN interactions

PLXNA3 MAN2A1 MGAT5 TMEM131 PLXNA1

1.45e-04711425int:FIBIN
InteractionSEMA5B interactions

PLXNA3 PLXNA1 PLXNA2

1.46e-04151423int:SEMA5B
InteractionCTRB2 interactions

CTRB2 CTRB1

1.47e-0431422int:CTRB2
InteractionEDNRB interactions

MMS22L ARFGEF1 GNA11 XPO7

1.60e-04391424int:EDNRB
InteractionNPTN interactions

SMG1 MMS22L GCFC2 KCTD13 DYNC2H1 ARFGEF1 IPO4 UTP20 XPO7

1.61e-042781429int:NPTN
InteractionRAB7A interactions

KCTD13 ATG7 KTN1 CNTRL ARFGEF1 TRIM39 STK11IP ARMCX3 ITPR1 ITPR2 ITPR3 DST TMEM131L TMEM131 PLXNA1 VPS13B PMAIP1

1.70e-0488614217int:RAB7A
InteractionTESPA1 interactions

ITPR1 ITPR2 ITPR3

1.79e-04161423int:TESPA1
InteractionARHGEF12 interactions

ARHGEF28 KCTD13 MYO6 DCTN2 GNAQ PLXNB1

1.81e-041171426int:ARHGEF12
Cytoband1p36.21

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

4.92e-056314541p36.21
GeneFamilyPlexins

PLXNA3 PLXNA1 PLXNA2 PLXNB1

6.48e-089884683
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2 ITPR3

1.11e-073883297
GeneFamilyPRAME family

PRAMEF1 PRAMEF2 PRAMEF13 PRAMEF14

5.17e-0624884686
GeneFamilyDyneins, axonemal

DNAH3 DNAH10 DNAH14

7.21e-0517883536
GeneFamilyATP binding cassette subfamily C

ABCC6 ABCC2

1.76e-0313882807
GeneFamilyATP binding cassette subfamily A

ABCA12 ABCA6

2.05e-0314882805
CoexpressionGSE3920_UNTREATED_VS_IFNA_TREATED_ENDOTHELIAL_CELL_DN

RDH13 ITPR1 TTC7B TBRG1 ANP32E GNAS ARHGAP19 XPO7

3.99e-061651458M6685
CoexpressionGRYDER_PAX3FOXO1_ENHANCERS_IN_TADS

DPY19L3 MAN2A1 MYO18A NUF2 N4BP3 ELMO1 TTLL7 ITPR1 SACS KCNMA1 TMEM131L WDFY3 GNAS GNAZ PLXNA1 VPS13B PLXNA2 XPO7

1.24e-05100914518M157
CoexpressionHAMAI_APOPTOSIS_VIA_TRAIL_UP

MYO6 CWC27 ICE2 KTN1 ARFGEF1 HAUS3 NUF2 ARMCX3 TTLL7 ITPR1 ITPR2 SACS PIK3CA USP48

1.77e-0565614514M18979
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

MAN2A1 ARFGEF1 SHOC2 ITPR1 KIFAP3 SLIT2 MGAT5 DST SACS TMEM131L UTP20 TMEM131 GNAQ WDFY3 VPS13B ARHGAP19

2.22e-0585614516M4500
CoexpressionGSE10147_IL3_VS_IL3_AND_CPG_STIM_PDC_DN

CCDC125 CWC27 R3HCC1 RDM1 KIFAP3 PLXNA1 PMAIP1

3.84e-051651457M353
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUF2 CLEC12A SPAG5 GDA ANP32E IQGAP3 ARHGAP19

1.33e-0616914474db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-dn_T|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP10B HAVCR2 TRANK1 CCR5 CREB3L3 SMIM43

2.26e-061171446e74dd01ccb6cc630759146655fccec359f725b1d
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-dn_T-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP10B HAVCR2 TRANK1 CCR5 CREB3L3 SMIM43

2.26e-0611714463c67e8a184b5a8302cba584e5ee97006f6cd267f
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-dn_T-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ATP10B HAVCR2 TRANK1 CCR5 CREB3L3 SMIM43

2.38e-061181446d95344ef24a1a838232186c02725f556c5fd51ac
ToppCellPBMC-Mild-Lymphocyte-T/NK-Other_T-dn_T|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

ATP10B HAVCR2 TRANK1 CCR5 CREB3L3 SMIM43

2.38e-061181446c234ea1969726356ee47d9364b716044cfbd125a
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

ARHGEF28 ITPR2 MGAT5 KCNMA1 GNAQ WDFY3 VPS13B

3.92e-06199144794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-dn_T|COVID-19_Mild / Disease, condition lineage and cell class

SAMD9 CNTRL ITPR3 HAVCR2 TRANK1 CCR5 CREB3L3

3.92e-061991447f307d4887b28cf60a591439e278fd668409cb104
ToppCellileum-BEST4+_Enterocytes|ileum / shred on tissue and cell subclass

MMS22L NPY1R SAMD9 PHTF2 ITPR2 PLA1A

1.10e-051541446608e9c982125e0c2c15b86b1920813845a0db81f
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPN2 ABCC6 ABCA6 PLA1A CREB3L3 ABCC2

1.19e-051561446e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCellE18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUF2 CLEC12A HAVCR2 GDA CCR5 IQGAP3

1.23e-051571446904cd98ae85ed6459e0663f077ac462842bf12df
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 DNAH10 SLC5A5 KCNMA1 CREB3L3 PLXNA2

1.27e-051581446f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCellfacs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP26B1 DNAH10 SLC5A5 KCNMA1 CREB3L3 PLXNA2

1.27e-0515814468c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCellfacs-Spleen-nan-3m-Hematologic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUCNR1 CLEC12A HAVCR2 GDA WDFY3 PMAIP1

1.42e-05161144645591addc765760db6029ac19e80573373d1d917
ToppCellfacs-Spleen-nan-3m-Hematologic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUCNR1 CLEC12A HAVCR2 GDA WDFY3 PMAIP1

1.42e-0516114468741b91a62c9a8ce377ef6533d323b65beb93c63
ToppCellfacs-Spleen-nan-3m-Hematologic-proerythroblast|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SUCNR1 CLEC12A HAVCR2 GDA WDFY3 PMAIP1

1.42e-0516114469cf1dcf0e7ca9e35c46c094a6b78f98d1f6b9276
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMS22L RDM1 NUF2 SPAG5 IQGAP3 ARHGAP19

2.66e-051801446334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell368C-Myeloid-Dendritic-cDC_proliferating_1|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

GCFC2 IPO4 STK11IP CLEC12A KCNMA1 XPO7

3.20e-0518614465cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

MYO6 RTTN ELMO1 TTLL7 ITPR1 KCNMA1

3.40e-051881446b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellControl-Endothelial-Endothelial-FOXM1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMS22L NUF2 SPAG5 ANP32E IQGAP3 ARHGAP19

3.50e-0518914461e1499b062d9c647c8f38b0c4e0d871d159be5dd
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ATG7 ELMO1 ITPR2 MGAT5 DHRS9 KCNMA1

3.60e-051901446f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-myeloid-myeloid_monocytic-intermediate_monocyte|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CCDC125 DNAH10 ARFGEF1 CLEC12A DHRS9 GNAQ

3.60e-051901446896b5825edb30fe62cbbed6078570c1f8057a99e
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTRL NUF2 SPAG5 ANP32E IQGAP3 ARHGAP19

3.60e-051901446cd37ccd30c27cf65eda0a9165f35b7672f5acaf6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R ITPR1 DST GNA14 ABCA6 KCNMA1

3.71e-051911446806b94f567ea09a9f443cd4091e70cdb1253ac08
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO6 ABCC6 DNAH14 ITPR3 FHIP1A PLXNA2

3.71e-051911446ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellCOVID-19_Mild-dn_T|COVID-19_Mild / Disease condition and Cell class

ATP10B HAVCR2 CCR5 CREB3L3 SMIM43

3.78e-05116144579c918f3bebfd5e0b865d2c7673af9ee3bc48779
ToppCellControl-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DNAH10 DYNC2H1 GNA14 DZIP3 CFAP69

3.93e-0519314460e37d454f3735edd936ee9a5f5f516ac3aad400e
ToppCellIPF-Epithelial-Ciliated|Epithelial / Disease state, Lineage and Cell class

DNAH3 DNAH10 DYNC2H1 GNA14 DZIP3 CFAP69

3.93e-051931446ad58f5080e0ba65c845056ea6b79037b636e9c64
ToppCellCOVID-19_Mild-Lymphoid_T/NK-dn_T|COVID-19_Mild / Disease group, lineage and cell class

HAVCR2 TRANK1 CCR5 CREB3L3 SMIM43

3.93e-0511714459d417dd137c27f8fe9e57842cd5515fdc2f2dc06
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ENOSF1 ARHGEF28 MYO6 DNAH14 GDA FHIP1A

4.05e-0519414467002937e8903e037332a215d00fbc7c7843b33f2
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SPAG1 DNAH10 DYNC2H1 DZIP3 CFAP69

4.05e-0519414464a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell3'-GW_trimst-1-LargeIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CNTRL NUF2 SPAG5 ANP32E GNAS ARHGAP19

4.16e-051951446742c82c86487314cdb3178012004adb1164bcbdb
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO6 DYNC2H1 ARFGEF1 TTLL7 RAD51AP2 DST

4.16e-0519514463e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYO6 DYNC2H1 ARFGEF1 TTLL7 RAD51AP2 DST

4.16e-0519514467796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DNAH3 SPAG1 DNAH10 DYNC2H1 DZIP3 CFAP69

4.28e-051961446de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellIPF-Epithelial|IPF / Disease state, Lineage and Cell class

DNAH3 DNAH10 DYNC2H1 GNA14 CFAP69 FHIP1A

4.28e-05196144687d9881cfec461a5d89b688a83749b618c519485
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SPAG1 DNAH10 DYNC2H1 DZIP3 CFAP69

4.41e-05197144691637bdeab85024b5a02d1066f76cb803a2d6420
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SPAG1 DNAH10 DYNC2H1 DZIP3 CFAP69

4.41e-05197144622c87dd15dc57bd0aa98a204c9fc9b3b9b573b45
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SPAG1 DNAH10 DYNC2H1 DZIP3 CFAP69

4.41e-0519714463bbf068d2ad8196fbc85d3f311a7c54c9aece856
ToppCellmild-dn_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CNTRL HAVCR2 TRANK1 CCR5 SMIM43 PMAIP1

4.41e-05197144607a1f59c83b748825e0708cd1cc7b63a2cb856cc
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 SPAG1 DNAH10 DYNC2H1 DZIP3 CFAP69

4.41e-05197144687db09f341e2b20eb6e1c3e917cb5c960387b3e9
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DNAH3 DNAH10 DYNC2H1 CNTRL DZIP3 CFAP69

4.53e-051981446ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellsevere-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

MMS22L NUF2 SUCNR1 SACS ANP32E IQGAP3

4.53e-051981446e36303628af3139310c1d7a84d2919b7319bbda4
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

SPAG1 SAMD9 KTN1 CNTRL DZIP3 GNAS

4.66e-05199144661b1ed2db71b96157b92b7535d1955a4033098da
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-2M-Proliferating-cycling_dorsal_progenitors|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.

CNTRL RDM1 NUF2 SPAG5 ANP32E IQGAP3

4.66e-051991446ca17e8c0f5bc2c41ce28351a7418d934404e563b
ToppCellLPS_IL1RA-Endothelial-Endothelial-FOXM1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MMS22L CNTRL RDM1 NUF2 SPAG5 IQGAP3

4.66e-051991446be2276c9a1994579ba1d2998b49bf549c1324d44
ToppCellLPS_IL1RA_TNF-Endothelial-Endothelial-FOXM1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

CNTRL RDM1 NUF2 SPAG5 ANP32E IQGAP3

4.79e-0520014464cfe08878a6981bf7b3567f9e82192d8f060ddde
ToppCellLPS-antiTNF-Unknown-Endothelial-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH10 RDM1 NUF2 SPAG5 IQGAP3

6.99e-05132144502491930097b75aaeedab9e8200711b0dc610944
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGEF28 CTRB2 RDM1 FHIP1A PLXNA2

7.25e-0513314455bf5e654653e2c340891f51e3f2a30441b7b6b2b
ToppCellfacs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 NUF2 TRANK1 KCNMA1 IQGAP3

9.55e-0514114454aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCellfacs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 NUF2 TRANK1 KCNMA1 IQGAP3

9.55e-051411445e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCellfacs-Heart-Unknown-3m-Endothelial|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA12 NUF2 TRANK1 KCNMA1 IQGAP3

9.87e-051421445759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell15-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

RDM1 NUF2 CCR5 CREB3L3 IQGAP3

1.12e-041461445ca722a89c6601e78f253d9484d01931f26161820
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CNKSR1 NUF2 GDA ABCC2 MYBPC2

1.12e-04146144545d7cb73776e60d22f335a651845e21e16948fcc
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5-Dad1_(Cspg5)-|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RHCG SUCNR1 PLA2G4C ABCA6

1.19e-0478144483d308b15cb3c0820a27b95c8bc85afadf98370e
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P3-Tnr-Polydendrocyte.Tnr.Cspg5-Dad1_(Cspg5)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

RHCG SUCNR1 PLA2G4C ABCA6

1.19e-04781444387e7e07a5a509dc8415a7cb83a2c3940ca1ec85
ToppCell10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-T_lymphocytic_-_developing-DN4_thymocyte|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

RDM1 NUF2 SPAG5 CREB3L3 SMIM43

1.24e-04149144589faa84af68d4727180f39718964bb3bc65d8fe6
ToppCell367C-Myeloid-Macrophage-FABP4+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ARHGEF28 RAD51AP2 GDA DST TTC7B

1.44e-0415414456c1e7682c43c40b58b371c58deb10b839700ebcc
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

EVC2 ARHGEF28 NTF3 SPAG5 ALOX12B

1.53e-0415614452cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PHTF2 STK11IP SPAG5 GDA LUZP2

1.58e-041571445370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-lymphocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC12A HAVCR2 PLA2G4C ABCA6 CCR5

1.68e-0415914453bab00f8fb7d9232538e50f83dd0fd70ddd16819
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_Cytotoxic_T_cells|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HAVCR2 CCR5 GNAQ FHIP1A SMIM43

1.68e-0415914452060e7ed5627976b48fea4a2328762b6fa308db1
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-CD45|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLEC12A HAVCR2 PLA2G4C ABCA6 CCR5

1.73e-0416014455bec867def73fa8531f8dad611679f4b44f573bd
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 RTTN HAVCR2 PLXNA1 ARHGAP19

1.88e-0416314458dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAH10 RTTN HAVCR2 PLXNA1 ARHGAP19

1.88e-041631445fd243ca223079033be480a24817a399f281fa4d4
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NUF2 CLEC12A HAVCR2 CCR5 IQGAP3

1.94e-0416414455638d95c7cc5e59c4a7bda30268a904a01861a5f
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IPO4 MGAT5 PLA1A SACS HERC3

1.99e-0416514450c80abf13409767825ef8a507b498afafa7e89c5
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IPO4 MGAT5 PLA1A SACS HERC3

1.99e-041651445cced77f2d74b07010307d7f4788b8cf3fdaeb91a
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NUF2 SPAG5 PLA2G4C IQGAP3 ARHGAP19

1.99e-04165144596f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCelllung-Ciliated_Epithelia|lung / shred on tissue and cell subclass

DNAH3 SPAG1 DYNC2H1 DHRS9 CFAP69

2.11e-04167144526cf1cfa58ee74794449a87eb19cd896e1ec8892
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A1 TTC7B PLA2G4C PLA1A LRRD1

2.11e-041671445528493896aebe7d03d4b6ad2341b12927859e2e4
ToppCellfacs-Marrow-Granulocytes-18m-Lymphocytic-naive_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAN2A1 TTC7B PLA2G4C PLA1A LRRD1

2.11e-041671445a82e85caf79395baa48380786d9df32a86dfd1ce
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_G2M|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HAUS3 NUF2 SPAG5 ANP32E ARHGAP19

2.11e-041671445d21635df8b74189e3309eaf435af381fbe412574
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-nan|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPY1R GDA DST PLA1A FHIP1A

2.16e-04168144504a7810f95196a21325356b42084f96c11af5964
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells-mDC|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUCNR1 CLEC12A TLR10 HAVCR2 DHRS9

2.16e-0416814452dca1c4a33b6da9357fa3b2a523af19baab1c21c
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMS22L RDM1 NUF2 SPAG5 IQGAP3

2.23e-041691445e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ENOSF1 DNAH3 DNAH10 DYNC2H1 CFAP69

2.23e-041691445fba841664939c771881ba97f14ef1df6635c04ff
ToppCell390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2|390C / Donor, Lineage, Cell class and subclass (all cells)

PHTF2 HAUS3 SPAG5 TMEM131L HERC3

2.23e-041691445cfc9ff103d13a2d5eacc457e800f53fdd29f7738
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 DYNC2H1 DZIP3 CFAP69

2.23e-04169144514aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellLPS-antiTNF-Myeloid-Dendritic_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUCNR1 CLEC12A TLR10 HAVCR2 DHRS9

2.29e-0417014453cbeea6bfa500928c413b1c6129f6dedc769cd1e
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA12 ATP10B SLC5A5 GDA DHRS9

2.35e-04171144525c1979e972c959e1ce4c57804f976f53a247ad7
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA12 ATP10B SLC5A5 GDA DHRS9

2.35e-041711445fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells-mDC|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUCNR1 CLEC12A TLR10 HAVCR2 DHRS9

2.41e-041721445cc0e2a45fa74ee19e41612c3615729462474003a
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHCG KCTD13 PTCHD3 NUF2

2.45e-0494144400b932421d77f0fd8d6ffe439c992ebc95ad7c94
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLXNA3 NUF2 STK11IP SPAG5 IQGAP3

2.55e-04174144572df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PLXNA3 NUF2 STK11IP SPAG5 IQGAP3

2.55e-041741445c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellASK452-Immune-B_cell|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

MMS22L ELMO1 SPAG5 ITPR2 LRRC27

2.55e-04174144569723f5666abc3af5f0431901a60246c9915ef81
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Macroglial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RHCG KCTD13 PTCHD3 NUF2

2.56e-04951444a09443e527d37adb637a66ca857525dab1c39a9b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

RHCG N4BP3 ITPR1 ITPR2 SLIT2

2.61e-04175144577c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 TTLL7 SCN5A KCNMA1 TMEM131L

2.61e-041751445d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellNS-moderate-d_0-4-Epithelial-Ionocyte|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MAN2A1 ITPR2 DST PLA2G4C KCNMA1

2.61e-041751445a1e0a15c69211d6db2edeb101476f0f6e08b90c8
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NTF3 TTLL7 SCN5A KCNMA1 TMEM131L

2.61e-041751445454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CLEC12A SPAG5 GDA ANP32E ARHGAP19

2.68e-04176144590f8bb11f339f67f08692a0c33dd420f5cda2861
ToppCellLPS-IL1RA-Myeloid-Dendritic_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SUCNR1 CLEC12A TLR10 HAVCR2 DHRS9

2.68e-041761445f3bbe8c1a8d132705eac360cf531261271d84588
ToppCell(01)_Cycling_Basal_(homeostasis)|World / shred by cell type and Timepoint

NUF2 SPAG5 ANP32E IQGAP3 ARHGAP19

2.75e-04177144505c57578142a6662f18b294d5cc11e6efd6b0f8e
ToppCell3'_v3-lymph-node_spleen-Myeloid_Mac-Intestinal_macrophages|lymph-node_spleen / Manually curated celltypes from each tissue

DYNC2H1 PROKR1 TTC7B DHRS9 ARHGAP19

2.75e-04177144552c2ba74a8605260a2623e7d151286e504ac4d19
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SMG1 GNA14 CCR5 NUDCD1 PLXNA1

2.83e-041781445c87945146b2734141f07b39d268e0d8086ee0364
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 DNAH10 DYNC2H1 WDR97 CFAP69

2.90e-0417914455e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellSomatosensory_Cortex_(S1)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CCDC168 ELMO1 ITPR2 SLIT2 GNA14

2.90e-04179144582348bf56a4525b2f485696cab5b2ea6e96c2f91
ToppCell(05)_Ciliated-(4)_1wkpi|(05)_Ciliated / shred by cell type and Timepoint

ARHGEF28 DNAH10 DHRS9 NUDCD1 CFAP69

2.98e-04180144585fc9b164147b28545e2397d32302eea03ef6346
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAH10 PEAK3 CLEC12A ELMO1 DHRS9

3.05e-041811445338c7362d258a87f1a6b1a65376f5394d4b2b4b2
Drugestradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A

DCTN2 ATP10B N4BP3 NEK9 TRANK1 SCN5A CFAP69 PLXNA2 PMAIP1

5.63e-0620014595601_UP
DrugNs 004

ITPR1 ITPR3 KCNMA1

1.38e-0581453CID000162750
DrugPhenoxybenzamine hydrochloride [63-92-3]; Down 200; 11.8uM; PC3; HT_HG-U133A

ARFGEF1 ITPR1 GNA14 TMEM131L GNAZ PLXNA1 VPS13B ARHGAP19

1.83e-0517714584652_DN
Drugmagnesium fluoride

MAN2A1 GNA14 GNAQ GNAS GNAZ

2.19e-05531455CID000024546
Drugcaged InsP3

NTF3 ITPR1 ITPR3 KCNMA1

3.31e-05291454CID000122248
Drug17-AAG; Up 200; 1uM; PC3; HG-U133A

DNAH3 NPY1R ARHGEF28 KTN1 KIFAP3 ARSA GNA14 GNA11

3.67e-051951458450_UP
DrugVitexin [3681-93-4]; Up 200; 9.2uM; MCF7; HT_HG-U133A

PLXNA3 NTF3 CNTRL MGAT5 LRRC8B WDFY3 ABCC2 VPS13B

3.95e-0519714582810_UP
Drug8-amino-cADPR

ITPR1 ITPR3 GNAQ

4.02e-05111453CID003081323
DrugBOCPheONP

CTRB2 CTRB1

4.03e-0521452CID000111308
DrugMPM-06

CTRB2 CTRB1

4.03e-0521452CID000161546
DrugNSC-374899

CTRB2 CTRB1

4.03e-0521452CID000435726
Drugadenophostin A

ITPR2 ITPR3

4.03e-0521452ctd:C085029
DrugIsocaffeine

ITPR1 ITPR3

4.03e-0521452CID000001326
Drugmethylbenzenebutanoate

CTRB2 CTRB1

4.03e-0521452CID000281254
DrugAsp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu

CTRB2 CTRB1

4.03e-0521452CID004418081
Drugadenophostin B

ITPR1 ITPR3

4.03e-0521452CID000656722
Drugc189

CTRB2 CTRB1

4.03e-0521452CID000248048
Drugdansyl-D-arginine methyl ester

CTRB2 CTRB1

4.03e-0521452CID000191369
Drugmethyl 6-phenylhexanoate

CTRB2 CTRB1

4.03e-0521452CID011820300
Drug5-aminotetrazole

CTRB2 CTRB1

4.03e-0521452CID000020467
Drug2-bromoisobutyric acid

CTRB2 CTRB1

4.03e-0521452CID000074924
Drugp-toluamidine

CTRB2 CTRB1

4.03e-0521452CID000122753
DrugN-acetyl-alpha-azaphenylalanine phenyl ester

CTRB2 CTRB1

4.03e-0521452CID000191275
Drugbenzene 1,2,4-trisphosphate

ITPR1 ITPR3

4.03e-0521452CID000192376
Drugisobutyl sulfide

CTRB2 CTRB1

4.03e-0521452CID000011607
DrugCP-690334-01 [459212-38-5]; Up 200; 1uM; MCF7; HT_HG-U133A

ARHGEF28 CYP26B1 ABCC6 TTLL7 ITPR1 PLA2G4C HERC3 ALOX12B

4.09e-0519814584383_UP
DrugCaffeic acid [3331-39-5]; Up 200; 22.2uM; HL60; HT_HG-U133A

CPN2 NEK9 ITPR2 ITPR3 TRANK1 PLA2G4C GNA11 GNAZ

4.09e-0519814583053_UP
DrugEthosuximide [77-67-8]; Up 200; 28.4uM; PC3; HT_HG-U133A

NPY1R KCTD13 MYO6 ATP10B NEK9 DHRS9 WDFY3 PLXNA2

4.24e-0519914587308_UP
DrugS 2484

GCFC2 CTRB2 CTRB1

8.75e-05141453CID000135164
DrugClorgyline

SAMD9 MYO6 DYNC2H1 KTN1 SHOC2 DST NUDCD1

1.03e-041681457ctd:D003010
DrugMX-68

ABCC6 WDFY3 ABCC2

1.09e-04151453CID006918310
DrugAHBs

CTRB2 CCR5 CTRB1

1.09e-04151453CID000193414
Drughexaconazole

ARHGEF28 CYP26B1 MYO6 SLC5A5 SLIT2 PMAIP1

1.16e-041191456ctd:C409722
Drug5-deoxy-5-fluoro-myo-inositol

ITPR1 ITPR3

1.20e-0431452CID000195110
DrugN-acetylbenzotriazole

CTRB2 CTRB1

1.20e-0431452CID000087784
Drugphotophor

CTRB2 CTRB1

1.20e-0431452CID000014780
Drugdibutyl iodomethaneboronate

CTRB2 CTRB1

1.20e-0431452CID000098591
Drugzinc;dipicolinate

CTRB2 CTRB1

1.20e-0431452CID004309911
Drug2-oxobut-3-ynoate

CTRB2 CTRB1

1.20e-0431452CID000171547
DrugAFMeq

CTRB2 CTRB1

1.20e-0431452CID000194069
DrugBz-Cti-otbu

CTRB2 CTRB1

1.20e-0431452CID006452691
Drugn-(2-oxoethyl)benzamide

CTRB2 CTRB1

1.20e-0431452CID000188995
DrugAC1L49DM

CTRB2 CTRB1

1.20e-0431452CID000152933
Drugc140

CTRB2 CTRB1

1.20e-0431452CID002783250
DrugBenzamidomethaneboronic acid

CTRB2 CTRB1

1.20e-0431452CID000127677
Drugphenyl hippurate

CTRB2 CTRB1

1.20e-0431452CID000076323
DrugFK-386

CTRB2 CTRB1

1.20e-0431452CID000135044
DrugFK-375

CTRB2 CTRB1

1.20e-0431452CID000135042
Drugcarbostyril-124

CTRB2 CTRB1

1.20e-0431452CID000088277
DrugN-trifluoroacetyl-4-fluorophenylalanine

CTRB2 CTRB1

1.20e-0431452CID000328214
DrugC18 4

CTRB2 CTRB1

1.20e-0431452CID000077248
Drugtaraxastane

CTRB2 CTRB1

1.20e-0431452CID006429404
DrugPhe-phe-ome

CTRB2 CTRB1

1.20e-0431452CID000151728
Drugphenylethaneboronic acid

CTRB2 CTRB1

1.20e-0431452CID000065389
Drug3-amino-2-pyridone

CTRB2 CTRB1

1.20e-0431452CID000322353
DrugASA-BMPA

CTRB2 CTRB1

1.20e-0431452CID003035649
Drugp-nitrophenyl benzoate

CTRB2 CTRB1

1.20e-0431452CID000070396
DrugZ-Phe-OMe

CTRB2 CTRB1

1.20e-0431452CID003082435
Drug3-methylcoumarin

CTRB2 CTRB1

1.20e-0431452CID000017130
Drug2-propyl methylphosphonochloridate

CTRB2 CTRB1

1.20e-0431452CID000102124
DrugFK-316

CTRB2 CTRB1

1.20e-0431452CID000133688
DrugAC1L19T8

CTRB2 CTRB1

1.20e-0431452CID000000694
DrugMarinostatin D

CTRB2 CTRB1

1.20e-0431452CID000132206
Drug1FD7

CTRB2 CTRB1

1.20e-0431452CID000445579
DrugGlt-leu-phe-nh-meq

CTRB2 CTRB1

1.20e-0431452CID000194914
DrugAC1L4Z4F

CTRB2 CTRB1

1.20e-0431452CID000194913
DrugGlt-Phe-NH-FMeq

CTRB2 CTRB1

1.20e-0431452CID000194912
Drugdiacetyl trimer

CTRB2 CTRB1

1.20e-0431452CID000193527
DrugFK-448

CTRB2 CTRB1

1.20e-0431452CID006917869
DrugAc-Phe-OMe

CTRB2 CTRB1

1.20e-0431452CID000097805
Drugthiobenzyl N-heptafluorobutyrylanthranilate

CTRB2 CTRB1

1.20e-0431452CID000133906
Drughp 5B

GNAQ GNAS GNAZ

2.27e-04191453CID000123651
Drugretinoic acid; Up 200; 1uM; MCF7; HG-U133A

DNAH3 CNKSR1 CYP26B1 DHRS9 GNA11 HERC3 PLXNB1

2.28e-041911457224_UP
DrugFludrocortisone acetate [514-36-3]; Down 200; 9.4uM; PC3; HT_HG-U133A

NPY1R KCTD13 PHTF2 ITPR1 LRRC8B PLXNB1 XPO7

2.36e-0419214574342_DN
DrugBenzoyl-dl-leucine

CTRB2 CTRB1

2.40e-0441452CID000294887
DrugAcafcek

CTRB2 CTRB1

2.40e-0441452CID000197677
DrugB-1,3-od

CTRB2 CTRB1

2.40e-0441452CID011971053
Drugfluorexon

ABCC6 ABCC2

2.40e-0441452ctd:C007740
Drugdehydromerodesmosine

CTRB2 CTRB1

2.40e-0441452CID006443540
Drugalpha-amyrin palmitate

CTRB2 CTRB1

2.40e-0441452CID000185477
Drugpoly-THIQ

CTRB2 CTRB1

2.40e-0441452CID006453487
DrugN-(4-carboxycyclohexylmethyl)-maleimide

CTRB2 CTRB1

2.40e-0441452CID011548799
DrugG2505_sigma

CTRB2 CTRB1

2.40e-0441452CID000111098
Drugp-fluorobenzenesulfonyl chloride

CTRB2 CTRB1

2.40e-0441452CID000009588
DrugBSSDA

CTRB2 CTRB1

2.40e-0441452CID003081106
DrugCHEBI:697555

ITPR1 ITPR3

2.40e-0441452CID009578246
DrugAC1L2HV6

CTRB2 CTRB1

2.40e-0441452CID000047328
DrugAC1L4X1Z

CTRB2 CTRB1

2.40e-0441452CID000193815
DrugNSC-676827

CTRB2 CTRB1

2.40e-0441452CID000385555
Drug6-amino-1,2-benzopyrone

CTRB2 CTRB1

2.40e-0441452CID000046152
Drugnitrophenylethanol

CTRB2 CTRB1

2.40e-0441452CID000097851
DrugMethyl benzethonium chloride [25155-18-4]; Down 200; 8.6uM; MCF7; HT_HG-U133A

NPY1R PHTF2 ATP10B SLIT2 KCNMA1 GNAZ VPS13B

2.43e-0419314573943_DN
DrugGuanfacine hydrochloride [29110-48-3]; Up 200; 14.2uM; PC3; HT_HG-U133A

KCTD13 DCTN2 MC2R KERA ITPR2 COMMD4 KCNMA1

2.51e-0419414574660_UP
DrugMedrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A

NPY1R SAMD9 PHTF2 NEK9 COMMD4 PLA2G4C GNAS

2.51e-0419414574727_DN
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

MC2R KERA ATP10B COMMD4 LRRC8B WDFY3 USP48

2.51e-0419414572223_UP
DrugClomiphene citrate (Z,E) [50-41-9]; Up 200; 6.6uM; MCF7; HT_HG-U133A

TTLL7 ITPR1 ABCA6 DHRS9 ABCC2 PLXNA2 PMAIP1

2.59e-0419514572624_UP
DrugGBR 12909 dihydrochloride [67469-78-7]; Down 200; 7.6uM; MCF7; HT_HG-U133A

SAMD9 CNTRL PHTF2 N4BP3 DZIP3 ABCC2 USP48

2.59e-0419514575702_DN
DrugPromazine hydrochloride [53-60-1]; Down 200; 12.4uM; HL60; HT_HG-U133A

KCTD13 PHTF2 NEK9 DZIP3 GNA11 WDFY3 PLXNA1

2.59e-0419514572173_DN
DrugPentamidine isethionate [140-64-7]; Down 200; 6.8uM; MCF7; HT_HG-U133A

ENOSF1 COMMD4 GNA14 DZIP3 LRRC8B WDFY3 PLXNA1

2.59e-0419514574396_DN
DrugTimolol maleate salt [26921-17-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A

DCTN2 MC2R PHTF2 NEK9 ITPR1 KCNMA1 WDFY3

2.67e-0419614576483_UP
Diseaseobesity (implicated_via_orthology)

NPY1R DNAH10 ITPR1 ITPR2 ITPR3 GNA14 GNA11 GNAQ PLXNB1

7.36e-072151369DOID:9970 (implicated_via_orthology)
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2 ITPR3

2.04e-05121363DOID:1441 (implicated_via_orthology)
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

2.11e-0521362C1140716
Diseaselevel of chymotrypsinogen B2 in blood serum

CTRB2 CTRB1

2.11e-0521362OBA_2041192
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

2.11e-0521362C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

2.11e-0521362C1527348
DiseasePhakomatosis cesioflammea

GNA11 GNAQ

2.11e-0521362C3838883
DiseaseAnoxia of brain

ITPR1 ITPR2

2.11e-0521362C0995195
DiseaseCongenital hemangioma

GNA11 GNAQ

2.11e-0521362C0235753
DiseasePort-wine stain with oculocutaneous melanosis

GNA11 GNAQ

2.11e-0521362C1274879
Diseasechymotrypsinogen B measurement

CTRB2 CTRB1

6.31e-0531362EFO_0801477
DiseaseIchthyosis Congenita I

ABCA12 ALOX12B

1.26e-0441362C4551630
DiseaseHarlequin Fetus

ABCA12 ALOX12B

1.26e-0441362C0239849
DiseaseIchthyosis Congenita II

ABCA12 ALOX12B

1.26e-0441362C3536797
DiseaseCollodion Fetus

ABCA12 ALOX12B

1.26e-0441362C3543867
Diseasecalcium measurement

ICE2 MYO18A PHTF2 ABCC6 ITPR1 ABCA6 HFM1 GNA11 TMEM131 GNAQ GNAS

1.64e-0462813611EFO_0004838
DiseaseCongenital ichthyosis

ABCA12 ALOX12B

2.09e-0451362C0020758
DiseaseMalignant melanoma of iris

GNA11 GNAQ

2.09e-0451362C0346373
DiseaseMalignant melanoma of choroid

GNA11 GNAQ

2.09e-0451362C0346388
DiseaseX-11423--O-sulfo-L-tyrosine measurement

ARSA PLXNA2

3.13e-0461362EFO_0021231
Diseasemental or behavioural disorder, substance abuse

HFM1 LUZP2

3.13e-0461362EFO_0000677, MONDO_0002491
DiseaseColorectal Carcinoma

DNAH3 EVC2 ABCA12 ARFGEF1 ABCC6 ATAD1 ABCA6 SACS PIK3CA GNAS ABCC2

4.23e-0470213611C0009402
Diseaseable to hear with hearing aids

ARHGEF28 MYO6

4.36e-0471362EFO_0009720
Diseasehepatitis A virus cellular receptor 2 measurement

ABCC6 HAVCR2

5.80e-0481362EFO_0008151
DiseaseUveal melanoma

GNA11 GNAQ

5.80e-0481362C0220633
DiseaseCutaneous Melanoma

PIK3CA GNA11 GNAQ

8.98e-04411363C0151779
Diseasequality of life during menstruation measurement, aggressive behavior

ATP10B PMAIP1

9.26e-04101362EFO_0003015, EFO_0009366
DiseaseCongenital Nonbullous Ichthyosiform Erythroderma

ABCA12 ALOX12B

1.13e-03111362C0079154
DiseaseCongenital ichthyosis of skin

ABCA12 ALOX12B

1.13e-03111362cv:C0020758
Diseasetrypsin-2 measurement

CTRB2 CTRB1

1.13e-03111362EFO_0008305
Diseasepancreatic cancer (is_marker_for)

CAB39 NUF2 GNAS ABCC2

1.25e-031011364DOID:1793 (is_marker_for)
Diseaseresponse to carboplatin, methylcobalamin deficiency type cblE, response to antineoplastic agent

ELMO1 LRRC8B

1.35e-03121362GO_0097327, GO_0097328, MONDO_0009354
DiseaseAdenocarcinoma Of Esophagus

ELMO1 PIK3CA

1.85e-03141362C0279628
DiseaseHMG CoA reductase inhibitor use measurement

CTRB2 ITPR3 ABCA6 HERC3 CTRB1

1.87e-031891365EFO_0009932
DiseaseObesity

NPY1R CYP26B1 KCNMA1 GNAS VPS13B

2.66e-032051365C0028754
DiseaseQT interval

ARHGEF28 CWC27 ELMO1 ITPR2 TTC7B SCN5A TMEM131L XPO7

3.41e-035341368EFO_0004682
Diseaseage at onset, smoking initiation

GCFC2 ITPR2

3.43e-03191362EFO_0004847, EFO_0005670
Diseaseovarian neoplasm

ATG7 SLC5A5 PIK3CA ALOX12B

3.49e-031341364C0919267
DiseaseGrand Mal Status Epilepticus

NTF3 KCNMA1 ABCC2

3.70e-03671363C0311335
DiseaseStatus Epilepticus, Subclinical

NTF3 KCNMA1 ABCC2

3.70e-03671363C0751522
DiseaseSimple Partial Status Epilepticus

NTF3 KCNMA1 ABCC2

3.70e-03671363C0751524
DiseaseNon-Convulsive Status Epilepticus

NTF3 KCNMA1 ABCC2

3.70e-03671363C0751523
DiseasePetit mal status

NTF3 KCNMA1 ABCC2

3.70e-03671363C0270823
DiseaseComplex Partial Status Epilepticus

NTF3 KCNMA1 ABCC2

3.70e-03671363C0393734
DiseaseMalignant neoplasm of ovary

ATG7 SLC5A5 PIK3CA ALOX12B

3.78e-031371364C1140680
DiseaseStatus Epilepticus

NTF3 KCNMA1 ABCC2

3.86e-03681363C0038220
Diseasegestational age

CWC27 SLIT2 MGAT5 GNAQ

3.88e-031381364EFO_0005112
DiseaseBMI-adjusted waist-hip ratio, physical activity measurement

DNAH10 CTRB2 CTRB1

4.02e-03691363EFO_0007788, EFO_0008002
Diseasecholangiocarcinoma (is_implicated_in)

GNAS ABCC2

4.59e-03221362DOID:4947 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
NLLKNIELFDKLALR

KCTD13

191

Q8WZ19
KFSILTVNNDITLLK

CTRB2

111

Q6GPI1
LTKQDNLALIKSLNL

CNTRL

91

Q7Z7A1
LFQNLSKLELLSLSK

CPN2

356

P22792
LKQNKEVLELAFSIL

ELMO1

631

Q92556
LALLNQFKSKLTQAI

CWC27

386

Q6UX04
NLSLLEQLKKLQAIV

CREB3L3

296

Q68CJ9
FSLRLLINESLIKKL

ABCA12

2201

Q86UK0
LLLFLTKVLKISDNR

ARFGEF1

1781

Q9Y6D6
LLKKAVLTNLVVFLL

ABCA6

321

Q8N139
ILDILLKNQAKLIEF

CAB39

291

Q9Y376
VEALQNLKNLKSLDL

ANP32E

106

Q9BTT0
VLCLTLFLNNIIKKI

DPY19L3

351

Q6ZPD9
LFLNNIIKKILNLKS

DPY19L3

356

Q6ZPD9
VLLAKQLAALKQQLV

DCTN2

136

Q13561
KNFQTLKIVILGLVL

CCR5

191

P51681
NEETKLQVLKLLLNL

ARMCX3

256

Q9UH62
IQQLFQKLKLLSLSQ

ATP10B

621

O94823
LDRFLLQKQLSKVLL

R3HCC1

26

Q9Y3T6
LDILLKTNIAFLLNN

RAD51AP2

576

Q09MP3
LVLKKQLAIELSQSA

RAD21L1

526

Q9H4I0
NSSVILFLNKKDLLE

GNAQ

266

P50148
LVLQLKNNASKLLLA

ITPR2

2036

Q14571
ETKLKILEILQFILN

ITPR3

966

Q14573
LFVLTTKNLFLIKVN

NUDCD1

566

Q96RS6
IQKALSDAFQKLLIV

RDM1

206

Q8NG50
LALLLTDVLLFLQEK

ARHGEF28

1106

Q8N1W1
NKLTFLAVEIFQLLK

LRRD1

336

A4D1F6
LQFLNILKTSNSIKL

KCNMA1

286

Q12791
DIKTLNIFLTKANLI

NEK9

176

Q8TD19
LVQKLLNKFIVESLT

MAN2A1

1096

Q16706
DLKKTLAVLLDNILQ

MGAT5

81

Q09328
DLVLELKNNASKLLL

ITPR1

2091

Q14643
KQLVKLTRLLFNLSE

MMS22L

851

Q6ZRQ5
LVLKNTQAAEALVKL

DST

1176

Q03001
VTKEFFLLLLKELLN

HERC3

746

Q15034
LAKLFLKVLAVELAS

CYP26B1

446

Q9NR63
VIFKQLLQAKALQFL

ENOSF1

311

Q7L5Y1
GVLKQLLSDLIEKNL

PLXNA1

1406

Q9UIW2
ALKLFAQLINNKVFL

PLXNA2

1351

O75051
GLLKQLLADLIEKNL

PLXNA3

1381

P51805
LSNLLNSKLFLTKFI

PLXNB1

1606

O43157
KLKSQEIFLNLKTAL

NUF2

416

Q9BZD4
LLQDSQKKIISNLFL

MYO18A

961

Q92614
VALLLLQLSAALKFL

PEAK3

281

Q6ZS72
QISKDIIALLLKNLT

EVC2

401

Q86UK5
NLLKAQLNETLTKLR

KTN1

1256

Q86UP2
VLLKSFLLKLVNDIF

ABCC2

321

Q92887
LKQLQLLKAQLDAAV

ARSA

456

P15289
LNSLIIKLIQADILK

NTF3

31

P20783
LIEKINFLLSALVIL

OR6M1

191

Q8NGM8
QSKQFDLCLLLALIK

DZIP3

461

Q86Y13
LLQLFKTALQEEIKS

IQGAP3

1006

Q86VI3
NVNLLIFLLNKKFLR

IQGAP3

1616

Q86VI3
DNLLVRFLLKKALTN

PIK3CA

646

P42336
ALAFLEENLKILRLK

LRRC8B

481

Q6P9F7
FLLTNLLLDKLKASA

RDH13

151

Q8NBN7
AQEKKFAVLLNSLIL

HFM1

901

A2PYH4
SGNLALIIIILKQKE

NPY1R

56

P25929
TLDVVVLLLALAKKN

PLA2G4C

496

Q9UP65
DLIQKLFDLLVLSLK

DYNC2H1

921

Q8NCM8
LFDLLVLSLKKSIQA

DYNC2H1

926

Q8NCM8
LNFRQKLLNLISKLF

PMAIP1

36

Q13794
KLVVLLNQLCSILAK

FHIP1A

161

Q05DH4
EKLSALKISNLFNIL

ICE2

831

Q659A1
LFNILQHILKKLSSL

ICE2

841

Q659A1
INTSLILFLNKKDLL

GNAZ

261

P19086
VLLNKFLLLTFADLK

ATG7

126

O95352
LLLQLKQELEILQKS

CCDC125

301

Q86Z20
ELILTFKTLLNSKRQ

DNAH3

2656

Q8TD57
LILVKIKALNQAESF

GCFC2

751

P16383
NSSVILFLNKKDLLE

GNA11

266

P29992
SVILFLNKQDLLAEK

GNAS

286

P63092
QLIKQKASFELLQLS

HAUS3

376

Q68CZ6
LSADKFQVLLAELKQ

COMMD4

176

Q9H0A8
ALLIVANSFLKEKVN

DNAH14

2176

Q0VDD8
LLFKAQQLTDLEQKL

LUZP2

171

Q86TE4
ILINFKATKFLNLNL

ALOX12B

186

O75342
NILLINKVNEKSLTL

GDA

351

Q9Y2T3
DLKAKQLLLSDILNT

CCDC168

5031

Q8NDH2
KSNFALLLKLSEELL

CYP20A1

136

Q6UW02
NNLETLLKRDFLKLL

FBXW2

46

Q9UKT8
IFLLLDLLALNQKKF

CFAP69

611

A5D8W1
DLLALNQKKFCNLIL

CFAP69

616

A5D8W1
LQDFLLLKQKAELAN

DHRS9

301

Q9BPW9
VLTKLILKNLQSFNS

DNAH10

871

Q8IVF4
LQQTNLKLFHSLKLL

SACS

3121

Q9NZJ4
KAALLLLLTFLAKQH

IPO4

1041

Q8TEX9
KFSILTVNNDITLLK

CTRB1

111

P17538
NFELLILVVSFLKKL

KIFAP3

316

Q92845
LLDQFTNIKNILALK

PTCHD3

346

Q3KNS1
LEHLQLLKIKLITFF

PRAMEF13

266

Q5VWM6
LNSSVILFLNKKDLL

GNA14

261

O95837
QLQKELIALFDTLLL

RTTN

1206

Q86VV8
VFQTQLALKLLQCLK

RTTN

1236

Q86VV8
QFLFDVLQKTLSLKL

STK11IP

76

Q8N1F8
KLKVLILNDNLISFL

SLITRK4

156

Q8IW52
EALAILAKLILNKAA

UTP20

441

O75691
LQKAIDLFTDAIKLN

ST13P4

126

Q8IZP2
ELTLVNNVLKLATKL

PHTF2

721

Q8N3S3
FALRKILKQLIADVT

TRIM39

326

Q9HCM9
LQSLTLFLQTKLKEK

SPAG5

881

Q96R06
NAKTSVLLLNKVDLL

TLR10

241

Q9BXR5
LKLAVKDIAINLFTN

TMEM131L

456

A2VDJ0
LQDEVLKLKLGLTLN

LRRC27

476

Q9C0I9
KAFVTLTVLNILNKA

ABCC6

566

O95255
SVFLRLEHLQLLKIK

PRAMEF14

261

Q5SWL7
LEHLQLLKIKLITFF

PRAMEF14

266

Q5SWL7
QSKEKLNFILANIIL

SAMD9

1381

Q5K651
ILFLNKQDLLAEKVL

GNAS

931

Q5JWF2
KEKIQNLSLISLANL

HAVCR2

231

Q8TDQ0
INKLLNKLFLINEQS

NEPRO

251

Q6NW34
NKLVLVKQLDNILAA

SMG1

181

Q96Q15
ALSQLKKLLFLFLED

KERA

116

O60938
IFVLSLLLILEKQAA

SEMG1

6

P04279
KINILAKINLLFVAI

SCN5A

1556

Q14524
LFLLLFVVIKQLKNS

SMIM43

21

Q4W5P6
SLEVLILSNNLLKKL

SHOC2

426

Q9UQ13
LFVLSLLLILEKQAA

SEMG2

6

Q02383
SVFLRLEHLQLLKIK

PRAMEF1

261

O95521
LEHLQLLKIKLITFF

PRAMEF1

266

O95521
EQLKILNLRFLGKLL

SUPT5H

1071

O00267
SVFLRLEHLQLLKIK

PRAMEF2

261

O60811
LEHLQLLKIKLITFF

PRAMEF2

266

O60811
AALQELLSKGLIKLV

RPS25

86

P62851
ANVKIFSEKLLLLLN

NCKIPSD

581

Q9NZQ3
ENLIVLLAVFKNKNL

MC2R

41

Q01718
RKKNLTLALEALVQL

ALG2

236

Q9H553
QKLAAAVFSLAIKLQ

ATAD1

171

Q8NBU5
ASLLKINNKNALEFI

CLEC12A

166

Q5QGZ9
LQSTLKAKLQELQVL

CNKSR1

626

Q969H4
KKLRNLTNLLIANLA

PROKR1

91

Q8TCW9
LKDLAFLKNQLESLQ

SLC35A4

11

L0R6Q1
VIKLSLEISLFLNKL

PLA1A

136

Q53H76
LVVLLSNQSILIKFK

WDFY3

1691

Q8IZQ1
KLLIDFIIQLIAQSK

WDFY3

2066

Q8IZQ1
KQAKLALLINQVGLF

SLC5A5

276

Q92911
QTQKKFVILALQLLL

WDR97

1266

A6NE52
LLLIQSLKNNLIEKD

SPAG1

851

Q07617
KLSLQTLNADIFLKQ

TMEM131

1581

Q92545
LFSLQLLLLNANKIN

SLIT2

371

O94813
NLLKLLLDLLYQTAK

ARHGAP19

241

Q14CB8
HLLQKKEFAILISLA

SUCNR1

131

Q9BXA5
LFAVNEFILLNLLKV

RHCG

161

Q9UBD6
ENFILLFSKVKLQSL

TTC7B

581

Q86TV6
LKANLSFTKLDQINL

VPS13B

2051

Q7Z7G8
SFTKLDQINLFLKKI

VPS13B

2056

Q7Z7G8
LDNALQTFIKLLLSI

XPO7

861

Q9UIA9
NLNLTVTLQDKLLKL

ZBED9

1216

Q6R2W3
LLDLLVKFDINFNLK

TRANK1

566

O15050
ALLVSANQTLKELKI

USP48

946

Q86UV5
ELQLRLLALQSASKK

ZFC3H1

371

O60293
LLKKLLQLQALTEGE

TBRG1

76

Q3YBR2
LQNLEKTIFCLQKLI

ZHX1-C8orf76

111

Q96EF9
LLNALKLLNIRTSDK

TTLL7

371

Q6ZT98
ISVGNKFKTQLNLLL

MYO6

641

Q9UM54
LAQKLAEIFSLKTQL

N4BP3

391

O15049
ALSLSAKLNFLEIKV

MYBPC2

516

Q14324