Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	enzyme regulator activity	DOCK10 MOB3B RGPD2 PPP2R1A PPP2R1B VAV3 LLGL1 CD33 WNT11 EIF2B2	4.63e-04	1418	41	10	GO:0030234
GeneOntologyMolecularFunction	small GTPase binding	DOCK10 RGPD2 XPO1 LLGL1 CYFIP2	4.85e-04	321	41	5	GO:0031267
GeneOntologyMolecularFunction	nucleoside-triphosphatase regulator activity	DOCK10 RGPD2 VAV3 LLGL1 WNT11 EIF2B2	5.50e-04	507	41	6	GO:0060589
GeneOntologyMolecularFunction	GTPase regulator activity	DOCK10 RGPD2 VAV3 LLGL1 WNT11 EIF2B2	5.50e-04	507	41	6	GO:0030695
GeneOntologyMolecularFunction	GTPase binding	DOCK10 RGPD2 XPO1 LLGL1 CYFIP2	8.14e-04	360	41	5	GO:0051020
GeneOntologyMolecularFunction	protein phosphatase regulator activity	PPP2R1A PPP2R1B CD33	1.13e-03	100	41	3	GO:0019888
GeneOntologyMolecularFunction	phosphatidylinositol phospholipase C activity	PLCG2 EDNRA	1.30e-03	26	41	2	GO:0004435
GeneOntologyMolecularFunction	phosphatase regulator activity	PPP2R1A PPP2R1B CD33	1.61e-03	113	41	3	GO:0019208
GeneOntologyMolecularFunction	phospholipase C activity	PLCG2 EDNRA	1.61e-03	29	41	2	GO:0004629
GeneOntologyMolecularFunction	enzyme activator activity	MOB3B RGPD2 VAV3 LLGL1 CD33 WNT11	2.07e-03	656	41	6	GO:0008047
GeneOntologyMolecularFunction	GTPase activator activity	RGPD2 VAV3 LLGL1 WNT11	2.52e-03	279	41	4	GO:0005096
GeneOntologyMolecularFunction	protein tyrosine kinase activity	MET CLK1 EDNRA	3.27e-03	145	41	3	GO:0004713
Domain	PP2A_A_meta	PPP2R1A PPP2R1B	4.94e-06	2	42	2	IPR031090
Domain	HEAT	PPP2R1A PPP2R1B CLASP2 XPO1	8.58e-06	58	42	4	IPR000357
Domain	HEAT_REPEAT	PPP2R1A PPP2R1B CLASP2 XPO1	1.82e-05	70	42	4	PS50077
Domain	HEAT	PPP2R1A PPP2R1B CLASP2	1.70e-04	48	42	3	PF02985
Domain	ARM-like	DOCK10 PPP2R1A PPP2R1B CLASP2 XPO1	3.34e-04	270	42	5	IPR011989
Domain	HEAT_type_2	PPP2R1A PPP2R1B	6.57e-04	17	42	2	IPR021133
Domain	ARM-type_fold	PPP2R1A PPP2R1B CLASP2 XPO1 NOC2L	9.38e-04	339	42	5	IPR016024
Domain	-	PPP2R1A PPP2R1B CLASP2 XPO1	1.53e-03	222	42	4	1.25.10.10
Pathway	REACTOME_AMPLIFICATION_OF_SIGNAL_FROM_THE_KINETOCHORES	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1	2.81e-06	100	32	5	MM14561
Pathway	REACTOME_MITOTIC_PROMETAPHASE	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1 EML4	5.34e-06	202	32	6	MM15362
Pathway	REACTOME_MITOTIC_SPINDLE_CHECKPOINT	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1	6.08e-06	117	32	5	MM15387
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DOCK10 RGPD2 PPP2R1A PPP2R1B CLASP2 VAV3 XPO1 RHOBTB1 CYFIP2	9.50e-06	649	32	9	MM15690
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1	9.80e-06	129	32	5	MM14894
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1	1.51e-05	141	32	5	MM15266
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1 CYFIP2	2.11e-05	257	32	6	MM14755
Pathway	REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	PPP2R1A PPP2R1B XPO1	2.36e-05	25	32	3	MM15379
Pathway	REACTOME_CYCLIN_A_B1_B2_ASSOCIATED_EVENTS_DURING_G2_M_TRANSITION	PPP2R1A PPP2R1B XPO1	2.36e-05	25	32	3	M808
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1	6.81e-05	193	32	5	MM14890
Pathway	REACTOME_MITOTIC_PROMETAPHASE	PPP2R1A PPP2R1B CLASP2 XPO1 EML4	8.85e-05	204	32	5	M4217
Pathway	REACTOME_PP2A_MEDIATED_DEPHOSPHORYLATION_OF_KEY_METABOLIC_FACTORS	PPP2R1A PPP2R1B	1.04e-04	7	32	2	M26992
Pathway	REACTOME_MITOTIC_SPINDLE_CHECKPOINT	PPP2R1A PPP2R1B CLASP2 XPO1	1.10e-04	111	32	4	M27673
Pathway	REACTOME_SIGNALING_BY_RHO_GTPASES_MIRO_GTPASES_AND_RHOBTB3	DOCK10 PPP2R1A PPP2R1B CLASP2 VAV3 XPO1 RHOBTB1 CYFIP2	1.57e-04	720	32	8	M41838
Pathway	REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1	1.69e-04	234	32	5	MM14898
Pathway	REACTOME_RESOLUTION_OF_SISTER_CHROMATID_COHESION	PPP2R1A PPP2R1B CLASP2 XPO1	1.86e-04	127	32	4	M27181
Pathway	REACTOME_M_PHASE	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1 EML4	2.04e-04	387	32	6	MM15364
Pathway	REACTOME_MASTL_FACILITATES_MITOTIC_PROGRESSION	PPP2R1A PPP2R1B	2.22e-04	10	32	2	M27176
Pathway	REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1	PPP2R1A PPP2R1B	2.22e-04	10	32	2	MM14509
Pathway	REACTOME_RHO_GTPASES_ACTIVATE_FORMINS	PPP2R1A PPP2R1B CLASP2 XPO1	2.70e-04	140	32	4	M27550
Pathway	REACTOME_REGULATION_OF_GLYCOLYSIS_BY_FRUCTOSE_2_6_BISPHOSPHATE_METABOLISM	PPP2R1A PPP2R1B	3.25e-04	12	32	2	M27950
Pathway	REACTOME_CELL_CYCLE_CHECKPOINTS	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1	3.33e-04	271	32	5	MM15388
Pathway	REACTOME_CELL_CYCLE	RGPD2 PPP2R1A PPP2R1B CLASP2 XPO1 FBXL7 EML4	3.34e-04	603	32	7	MM14635
Pathway	REACTOME_INHIBITION_OF_REPLICATION_INITIATION_OF_DAMAGED_DNA_BY_RB1_E2F1	PPP2R1A PPP2R1B	3.83e-04	13	32	2	M1015
Pathway	REACTOME_ERKS_ARE_INACTIVATED	PPP2R1A PPP2R1B	3.83e-04	13	32	2	MM14811
Pathway	REACTOME_ERKS_ARE_INACTIVATED	PPP2R1A PPP2R1B	3.83e-04	13	32	2	M8410
Pathway	REACTOME_SIGNALING_BY_CTNNB1_PHOSPHO_SITE_MUTANTS	PPP2R1A PPP2R1B	5.15e-04	15	32	2	M27407
Pathway	KEGG_MEDICUS_REFERENCE_COHESIN_DISSOCIATION_IN_PROPHASE	PPP2R1A PPP2R1B	5.87e-04	16	32	2	M47870
Pathway	REACTOME_DARPP_32_EVENTS	PPP2R1A PPP2R1B	5.87e-04	16	32	2	MM14699
Pathway	REACTOME_PLATELET_SENSITIZATION_BY_LDL	PPP2R1A PPP2R1B	6.65e-04	17	32	2	MM15096
Pathway	REACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE	PPP2R1A PPP2R1B	6.65e-04	17	32	2	M27083
Pathway	REACTOME_PLATELET_SENSITIZATION_BY_LDL	PPP2R1A PPP2R1B	6.65e-04	17	32	2	M919
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	PPP2R1A PPP2R1B CLASP2 XPO1 CYFIP2	7.41e-04	323	32	5	M27080
Pathway	REACTOME_BETA_CATENIN_PHOSPHORYLATION_CASCADE	PPP2R1A PPP2R1B	7.47e-04	18	32	2	MM14759
Pathway	REACTOME_MITOTIC_G2_G2_M_PHASES	PPP2R1A PPP2R1B XPO1 FBXL7	7.59e-04	184	32	4	MM15145
Pathway	KEGG_MEDICUS_REFERENCE_PP2A_AKT_SIGNALING_PATHWAY	PPP2R1A PPP2R1B	8.33e-04	19	32	2	M47525
Pathway	KEGG_MEDICUS_REFERENCE_TCR_PLCG_ITPR_SIGNALING_PATHWAY	VAV3 PLCG2	8.33e-04	19	32	2	M47733
Pathway	REACTOME_ERK_MAPK_TARGETS	PPP2R1A PPP2R1B	8.33e-04	19	32	2	MM14780
Pathway	REACTOME_SEPARATION_OF_SISTER_CHROMATIDS	PPP2R1A PPP2R1B CLASP2 XPO1	8.73e-04	191	32	4	M29614
Pathway	KEGG_MEDICUS_REFERENCE_CONDENSIN_LOADING	PPP2R1A PPP2R1B	9.25e-04	20	32	2	M47876
Pathway	REACTOME_CTLA4_INHIBITORY_SIGNALING	PPP2R1A PPP2R1B	1.02e-03	21	32	2	M5876
Pathway	REACTOME_CTLA4_INHIBITORY_SIGNALING	PPP2R1A PPP2R1B	1.02e-03	21	32	2	MM14996
Pathway	REACTOME_MITOTIC_G2_G2_M_PHASES	PPP2R1A PPP2R1B XPO1 FBXL7	1.04e-03	200	32	4	M864
Pathway	REACTOME_E2F_MEDIATED_REGULATION_OF_DNA_REPLICATION	PPP2R1A PPP2R1B	1.12e-03	22	32	2	M6768
Pathway	KEGG_MEDICUS_REFERENCE_CD80_CD86_CTLA4_PP2A_SIGNALING_PATHWAY	PPP2R1A PPP2R1B	1.12e-03	22	32	2	M47919
Pathway	REACTOME_ERK_MAPK_TARGETS	PPP2R1A PPP2R1B	1.12e-03	22	32	2	M13408
Pathway	REACTOME_DARPP_32_EVENTS	PPP2R1A PPP2R1B	1.34e-03	24	32	2	M751
Pathway	REACTOME_CELL_CYCLE_MITOTIC	PPP2R1A PPP2R1B CLASP2 XPO1 FBXL7 EML4	1.45e-03	561	32	6	M5336
Pathway	WP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY	PPP2R1A PPP2R1B WNT11	1.52e-03	101	32	3	MM15829
Pathway	WP_WNT_SIGNALING_AND_PLURIPOTENCY	PPP2R1A PPP2R1B WNT11	1.52e-03	101	32	3	M39387
Pathway	REACTOME_NUCLEAR_EVENTS_KINASE_AND_TRANSCRIPTION_FACTOR_ACTIVATION	PPP2R1A PPP2R1B	1.69e-03	27	32	2	MM14779
Pathway	REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES	PPP2R1A PPP2R1B	1.82e-03	28	32	2	MM15132
Pathway	REACTOME_MITOTIC_METAPHASE_AND_ANAPHASE	PPP2R1A PPP2R1B CLASP2 XPO1	1.91e-03	236	32	4	M27185
Pathway	REACTOME_DAP12_SIGNALING	VAV3 PLCG2	1.95e-03	29	32	2	M27171
Pathway	REACTOME_SIGNALING_BY_WNT	PPP2R1A PPP2R1B XPO1 WNT11	2.00e-03	239	32	4	MM14756
Pathway	PID_CDC42_REG_PATHWAY	DOCK10 VAV3	2.09e-03	30	32	2	M83
Pathway	REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	MET PPP2R1A PPP2R1B	2.10e-03	113	32	3	MM14783
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	VAV3 PLCG2 CYFIP2	2.15e-03	114	32	3	MM14814
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	PPP2R1A PPP2R1B	2.23e-03	31	32	2	M27400
Pathway	REACTOME_DISASSEMBLY_OF_THE_DESTRUCTION_COMPLEX_AND_RECRUITMENT_OF_AXIN_TO_THE_MEMBRANE	PPP2R1A PPP2R1B	2.23e-03	31	32	2	MM15154
Pathway	REACTOME_MAPK_TARGETS_NUCLEAR_EVENTS_MEDIATED_BY_MAP_KINASES	PPP2R1A PPP2R1B	2.23e-03	31	32	2	M15195
Pathway	REACTOME_DAP12_SIGNALING	VAV3 PLCG2	2.23e-03	31	32	2	MM14886
Pathway	REACTOME_M_PHASE	PPP2R1A PPP2R1B CLASP2 XPO1 EML4	2.30e-03	417	32	5	M27662
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	MET PPP2R1A PPP2R1B VAV3 CYFIP2	2.33e-03	418	32	5	MM15587
Pathway	REACTOME_NEGATIVE_REGULATION_OF_THE_PI3K_AKT_NETWORK	MET PPP2R1A PPP2R1B	2.38e-03	118	32	3	M713
Pathway	REACTOME_TOLL_LIKE_RECEPTOR_4_TLR4_CASCADE	PPP2R1A PPP2R1B PLCG2	2.61e-03	122	32	3	MM14640
Pathway	REACTOME_SIGNALING_BY_WNT_IN_CANCER	PPP2R1A PPP2R1B	2.68e-03	34	32	2	M27405
Pathway	REACTOME_RAF_ACTIVATION	PPP2R1A PPP2R1B	2.68e-03	34	32	2	M27556
Pathway	WP_GLYCOGEN_METABOLISM	PPP2R1A PPP2R1B	2.68e-03	34	32	2	MM15985
Pathway	WP_COHESIN_COMPLEX_CORNELIA_DE_LANGE_SYNDROME	PPP2R1A PPP2R1B	2.68e-03	34	32	2	M42555
Pathway	REACTOME_RAF_ACTIVATION	PPP2R1A PPP2R1B	2.83e-03	35	32	2	MM15271
Pathway	REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	VAV3 PLCG2	2.83e-03	35	32	2	MM14512
Pathway	REACTOME_GPVI_MEDIATED_ACTIVATION_CASCADE	VAV3 PLCG2	2.83e-03	35	32	2	M773
Pathway	REACTOME_REGULATION_OF_TP53_DEGRADATION	PPP2R1A PPP2R1B	3.00e-03	36	32	2	MM15339
Pathway	REACTOME_REGULATION_OF_TP53_EXPRESSION_AND_DEGRADATION	PPP2R1A PPP2R1B	3.16e-03	37	32	2	M27641
Pathway	KEGG_TIGHT_JUNCTION	PPP2R1A PPP2R1B LLGL1	3.26e-03	132	32	3	M11355
Pathway	REACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT	MET TRPM1 XPO1	3.62e-03	137	32	3	M48232
Pathway	WP_GLYCOGEN_SYNTHESIS_AND_DEGRADATION	PPP2R1A PPP2R1B	3.69e-03	40	32	2	M39595
Pathway	WP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY	VAV3 PLCG2	3.69e-03	40	32	2	M39695
Pathway	PID_ECADHERIN_STABILIZATION_PATHWAY	MET CYFIP2	3.87e-03	41	32	2	M232
Pathway	REACTOME_CELL_CYCLE_CHECKPOINTS	PPP2R1A PPP2R1B CLASP2 XPO1	4.06e-03	291	32	4	M16647
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	PPP2R1A PPP2R1B	4.06e-03	42	32	2	MM15274
Pathway	REACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS	VAV3 PLCG2 CYFIP2	4.09e-03	143	32	3	M27107
Pathway	REACTOME_CELL_CYCLE	PPP2R1A PPP2R1B CLASP2 XPO1 FBXL7 EML4	4.21e-03	694	32	6	M543
Pathway	REACTOME_NEGATIVE_REGULATION_OF_MAPK_PATHWAY	PPP2R1A PPP2R1B	4.25e-03	43	32	2	M27560
Pathway	REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1	PPP2R1A PPP2R1B	4.45e-03	44	32	2	MM15377
Pathway	KEGG_WNT_SIGNALING_PATHWAY	PPP2R1A PPP2R1B WNT11	4.76e-03	151	32	3	M19428
Pathway	REACTOME_DAP12_INTERACTIONS	VAV3 PLCG2	4.85e-03	46	32	2	M27151
Pathway	WP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY	VAV3 PLCG2	4.85e-03	46	32	2	MM15837
Pathway	REACTOME_ADAPTIVE_IMMUNE_SYSTEM	PPP2R1A TRIM71 PPP2R1B PLCG2 FBXL7 CD33	5.01e-03	719	32	6	MM14540
Pathway	REACTOME_CYCLIN_D_ASSOCIATED_EVENTS_IN_G1	PPP2R1A PPP2R1B	5.06e-03	47	32	2	M29724
Pathway	REACTOME_TOLL_LIKE_RECEPTOR_CASCADES	PPP2R1A PPP2R1B PLCG2	5.12e-03	155	32	3	MM14665
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY	PPP2R1A PPP2R1B NOC2L	5.30e-03	157	32	3	MM15226
Pathway	WP_CANCER_PATHWAYS	MET PLCG2 EML4 EDNRA WNT11	5.32e-03	507	32	5	M48302
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	PPP2R1A PPP2R1B XPO1	5.40e-03	158	32	3	MM14791
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	MET PPP2R1A PPP2R1B XPO1	5.55e-03	318	32	4	MM15278
Pathway	REACTOME_REGULATION_OF_TP53_ACTIVITY	PPP2R1A PPP2R1B NOC2L	5.59e-03	160	32	3	M27498
Pathway	REACTOME_MAPK_FAMILY_SIGNALING_CASCADES	MET PPP2R1A PPP2R1B XPO1	6.12e-03	327	32	4	M27565
Pathway	REACTOME_SIGNALING_BY_WNT	PPP2R1A PPP2R1B XPO1 WNT11	6.32e-03	330	32	4	M7847
Pathway	REACTOME_SIGNALING_BY_RECEPTOR_TYROSINE_KINASES	MET PPP2R1A PPP2R1B VAV3 CYFIP2	6.51e-03	532	32	5	M27870
Pubmed	Infrequent mutations of the PPP2R1A and PPP2R1B genes in patients with ovarian cancer.	PPP2R1A PPP2R1B	1.42e-06	2	42	2	23588898
Pubmed	alpha- and beta-forms of the 65-kDa subunit of protein phosphatase 2A have a similar 39 amino acid repeating structure.	PPP2R1A PPP2R1B	1.42e-06	2	42	2	2159327
Pubmed	ATG5 is required for B cell polarization and presentation of particulate antigens.	RGPD2 PPP2R1A CLASP2 PLCG2 MYO1D EML4 CYFIP2 EIF2B2	1.69e-06	701	42	8	30196744
Pubmed	PP4R4/KIAA1622 forms a novel stable cytosolic complex with phosphoprotein phosphatase 4.	PPP2R1A PPP2R1B CCT4	1.84e-06	20	42	3	18715871
Pubmed	The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.	PPP2R1A PPP2R1B INTS11	3.70e-06	25	42	3	34004147
Pubmed	Interaction between protein phosphatase 2A and members of the importin beta superfamily.	PPP2R1A PPP2R1B	4.27e-06	3	42	2	12670497
Pubmed	Hypoxia-activated Smad3-specific dephosphorylation by PP2A.	PPP2R1A PPP2R1B	8.53e-06	4	42	2	19951945
Pubmed	Neutrophil-mediated oxidative burst and host defense are controlled by a Vav-PLCgamma2 signaling axis in mice.	VAV3 PLCG2	8.53e-06	4	42	2	17932569
Pubmed	CRL4-DCAF1 ubiquitin E3 ligase directs protein phosphatase 2A degradation to control oocyte meiotic maturation.	PPP2R1A PPP2R1B	8.53e-06	4	42	2	26281983
Pubmed	Interaction of the protein phosphatase 2A with the regulatory domain of the cystic fibrosis transmembrane conductance regulator channel.	PPP2R1A PPP2R1B	8.53e-06	4	42	2	15936019
Pubmed	The novel ubiquitin ligase complex, SCF(Fbxw4), interacts with the COP9 signalosome in an F-box dependent manner, is mutated, lost and under-expressed in human cancers.	PPP2R1A PPP2R1B CCT4	1.14e-05	36	42	3	23658844
Pubmed	C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.	PPP2R1A CCT4 CLASP2 XPO1	1.32e-05	119	42	4	35776542
Pubmed	Vav1 and vav3 have critical but redundant roles in mediating platelet activation by collagen.	VAV3 PLCG2	1.42e-05	5	42	2	15456756
Pubmed	Analysis of EGFR, EML4-ALK, KRAS, and c-MET mutations in Chinese lung adenocarcinoma patients.	MET EML4	1.42e-05	5	42	2	23919423
Pubmed	Protein phosphatase 2A interacts with and directly dephosphorylates RelA.	PPP2R1A PPP2R1B	1.42e-05	5	42	2	11591705
Pubmed	Generation and annotation of the DNA sequences of human chromosomes 2 and 4.	DOCK10 RGPD2 CCT4 XPO1 CSRNP3 EML4	1.45e-05	442	42	6	15815621
Pubmed	The dependence receptor UNC5H2/B triggers apoptosis via PP2A-mediated dephosphorylation of DAP kinase.	PPP2R1A PPP2R1B	2.13e-05	6	42	2	21172653
Pubmed	A PP2A phosphatase high density interaction network identifies a novel striatin-interacting phosphatase and kinase complex linked to the cerebral cavernous malformation 3 (CCM3) protein.	PPP2R1A PPP2R1B CCT4	2.40e-05	46	42	3	18782753
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DOCK10 PPP2R1A CCT4 PLCG2 XPO1 LLGL1 NOC2L EML4 INTS11	2.78e-05	1353	42	9	29467282
Pubmed	PLK1 is a binding partner and a negative regulator of FOXO3 tumor suppressor.	PPP2R1A PPP2R1B	3.97e-05	8	42	2	26280018
Pubmed	Type 2A protein phosphatase, the complex regulator of numerous signaling pathways.	PPP2R1A PPP2R1B	3.97e-05	8	42	2	11007961
Pubmed	Characterization of the Aalpha and Abeta subunit isoforms of protein phosphatase 2A: differences in expression, subunit interaction, and evolution.	PPP2R1A PPP2R1B	3.97e-05	8	42	2	12370081
Pubmed	Differential expression of the catalytic subunits for PP-1 and PP-2A and the regulatory subunits for PP-2A in mouse eye.	PPP2R1A PPP2R1B	5.10e-05	9	42	2	18432318
Pubmed	Caveolin-1 maintains activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A.	PPP2R1A PPP2R1B	5.10e-05	9	42	2	14645548
Pubmed	The zinc finger cluster domain of RanBP2 is a specific docking site for the nuclear export factor, exportin-1.	RGPD2 XPO1	5.10e-05	9	42	2	10601307
Pubmed	USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.	PPP2R1A PPP2R1B CCT4 XPO1 MYO1D NOC2L	5.71e-05	565	42	6	33567341
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	PPP2R1A PPP2R1B CCT4 XPO1	5.97e-05	175	42	4	25756610
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	MET PPP2R1A PPP2R1B CCT4 XPO1 INTS11	6.18e-05	573	42	6	28330616
Pubmed	The RanBP2/RanGAP1*SUMO1/Ubc9 SUMO E3 ligase is a disassembly machine for Crm1-dependent nuclear export complexes.	RGPD2 XPO1	6.37e-05	10	42	2	27160050
Pubmed	Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics.	PPP2R1A PPP2R1B XPO1 EIF2B2	7.10e-05	183	42	4	23956138
Pubmed	Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.	PPP2R1A LLGL1 CYFIP2	7.77e-05	68	42	3	14676191
Pubmed	The adaptor SAP controls NK cell activation by regulating the enzymes Vav-1 and SHIP-1 and by enhancing conjugates with target cells.	VAV3 PLCG2	7.78e-05	11	42	2	22683124
Pubmed	Streamlined analysis schema for high-throughput identification of endogenous protein complexes.	PPP2R1A PPP2R1B INTS11	8.84e-05	71	42	3	20133760
Pubmed	Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis.	PPP2R1A PPP2R1B CCT4 XPO1	9.08e-05	195	42	4	17110338
Pubmed	Protein phosphatase 2A protects centromeric sister chromatid cohesion during meiosis I.	PPP2R1A PPP2R1B	9.32e-05	12	42	2	16541024
Pubmed	Enhanced prediction of Src homology 2 (SH2) domain binding potentials using a fluorescence polarization-derived c-Met, c-Kit, ErbB, and androgen receptor interactome.	MET VAV3 PLCG2	9.60e-05	73	42	3	24728074
Pubmed	PP2A1 binding, cell transducing and apoptotic properties of Vpr(77-92): a new functional domain of HIV-1 Vpr proteins.	PPP2R1A PPP2R1B	1.10e-04	13	42	2	21072166
Pubmed	Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.	DOCK10 TRPM1 XPO1 MYO1D	1.16e-04	208	42	4	33230847
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	CCT4 XPO1 LLGL1 MYO1D EML4	1.19e-04	401	42	5	25852190
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	RGPD2 PPP2R1A PPP2R1B CCT4 XPO1 MYO1D	1.20e-04	647	42	6	26618866
Pubmed	Direct activation of protein phosphatase-2A0 by HIV-1 encoded protein complex NCp7:vpr.	PPP2R1A PPP2R1B	1.28e-04	14	42	2	9013886
Pubmed	Increasing the ratio of PP2A core enzyme to holoenzyme inhibits Tat-stimulated HIV-1 transcription and virus production.	PPP2R1A PPP2R1B	1.28e-04	14	42	2	9400615
Pubmed	Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry.	PPP2R1A PPP2R1B CCT4 MYO1D NOC2L	1.34e-04	411	42	5	36652389
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	GPR161 PPP2R1A PPP2R1B CCT4 CLASP2	1.68e-04	432	42	5	23455922
Pubmed	Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.	TMEFF1 TRIM71 FBXL7 LY75 CLK1	1.68e-04	432	42	5	7671812
Pubmed	c-Met and NF-κB-dependent overexpression of Wnt7a and -7b and Pax2 promotes cystogenesis in polycystic kidney disease.	MET WNT11	1.69e-04	16	42	2	22677559
Pubmed	Regulation of HIV-1 transcription by protein phosphatase 1.	PPP2R1A PPP2R1B	1.91e-04	17	42	2	17266553
Pubmed	[Action of protein phosphatase-1 on Tat-dependent HIV-1 transcription and its related inhibitors].	PPP2R1A PPP2R1B	1.91e-04	17	42	2	21351466
Pubmed	ARHGAP24 represses β-catenin transactivation-induced invasiveness in hepatocellular carcinoma mainly by acting as a GTPase-independent scaffold.	DOCK10 PPP2R1A CCT4 XPO1 NOC2L	2.05e-04	451	42	5	36168627
Pubmed	The planar cell polarity gene Vangl2 is required for mammalian kidney-branching morphogenesis and glomerular maturation.	MET FRAS1 WNT11	2.10e-04	95	42	3	20843830
Pubmed	SLFN11 Inactivation Induces Proteotoxic Stress and Sensitizes Cancer Cells to Ubiquitin Activating Enzyme Inhibitor TAK-243.	PPP2R1A CCT4 MYO1D	2.10e-04	95	42	3	33863777
Pubmed	Molecular mechanisms involved in HIV-1-Tat mediated inhibition of telomerase activity in human CD4(+) T lymphocytes.	PPP2R1A PPP2R1B	2.15e-04	18	42	2	23287597
Pubmed	Proteomic screening of glutamatergic mouse brain synaptosomes isolated by fluorescence activated sorting.	PPP2R1A PPP2R1B	2.15e-04	18	42	2	24413018
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PPP2R1A CCT4 CLASP2 XPO1 MYO1D CYFIP2 INTS11	2.39e-04	1049	42	7	27880917
Pubmed	Ppp2r2a Knockout Mice Reveal That Protein Phosphatase 2A Regulatory Subunit, PP2A-B55α, Is an Essential Regulator of Neuronal and Epidermal Embryonic Development.	PPP2R1A PPP2R1B	2.40e-04	19	42	2	32582689
Pubmed	Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14.	CCT4 XPO1	2.40e-04	19	42	2	12174196
Pubmed	Shugoshin collaborates with protein phosphatase 2A to protect cohesin.	PPP2R1A PPP2R1B	2.40e-04	19	42	2	16541025
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PPP2R1A CCT4 CLASP2 XPO1 MYO1D NOC2L CYFIP2 INTS11	2.65e-04	1425	42	8	30948266
Pubmed	Selected reaction monitoring mass spectrometry reveals the dynamics of signaling through the GRB2 adaptor.	CLASP2 VAV3 CYFIP2	2.66e-04	103	42	3	21706016
Pubmed	Protein phosphatase 2A catalytic subunit α (PP2Acα) maintains survival of committed erythroid cells in fetal liver erythropoiesis through the STAT5 pathway.	PPP2R1A PPP2R1B	2.67e-04	20	42	2	21514445
Pubmed	An integrated workflow for charting the human interaction proteome: insights into the PP2A system.	PPP2R1A PPP2R1B CCT4	2.82e-04	105	42	3	19156129
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	PPP2R1A CCT4 XPO1 MYO1D NOC2L	2.84e-04	484	42	5	31995728
Pubmed	Identification of FBXO25-interacting proteins using an integrated proteomics approach.	CCT4 XPO1 MYO1D	3.41e-04	112	42	3	20473970
Pubmed	Sema4C-Plexin B2 signalling modulates ureteric branching in developing kidney.	MET WNT11	3.54e-04	23	42	2	21035938
Pubmed	The B-cell antigen receptor signals through a preformed transducer module of SLP65 and CIN85.	VAV3 PLCG2	3.86e-04	24	42	2	21822214
Pubmed	SARS-CoV-2 NSP12 associates with TRiC and the P323L substitution acts as a host adaption.	PPP2R1A CCT4 XPO1	4.17e-04	120	42	3	37929963
Pubmed	In vivo validation of late-onset Alzheimer's disease genetic risk factors.	CLASP2 PLCG2	4.20e-04	25	42	2	38687251
Pubmed	HIV-1 Vpr induces cell cycle G2 arrest in fission yeast (Schizosaccharomyces pombe) through a pathway involving regulatory and catalytic subunits of PP2A and acting on both Wee1 and Cdc25.	PPP2R1A PPP2R1B	4.54e-04	26	42	2	11531413
Pubmed	A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.	PPP2R1A CCT4 XPO1	4.70e-04	125	42	3	21654808
Pubmed	MHC class II-associated proteins in B-cell exosomes and potential functional implications for exosome biogenesis.	DOCK10 CCT4 PLCG2 LY75 CYFIP2	5.76e-04	565	42	5	20458337
Pubmed	The E3 ubiquitin ligase and RNA-binding protein ZNF598 orchestrates ribosome quality control of premature polyadenylated mRNAs.	CCT4 CLASP2 XPO1 EIF2B2	5.98e-04	320	42	4	28685749
Pubmed	Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis.	MET WNT11	6.47e-04	31	42	2	19898483
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	PPP2R1A CCT4 CLASP2 XPO1 PEX11B MYO1D CYFIP2	6.73e-04	1247	42	7	27684187
Pubmed	LINC01554-Mediated Glucose Metabolism Reprogramming Suppresses Tumorigenicity in Hepatocellular Carcinoma via Downregulating PKM2 Expression and Inhibiting Akt/mTOR Signaling Pathway.	PPP2R1A CCT4 XPO1	6.81e-04	142	42	3	30809309
Pubmed	Secondary Placental Defects in Cxadr Mutant Mice.	MET WNT11	6.90e-04	32	42	2	31338035
Pubmed	The tumor suppressor PP2A Abeta regulates the RalA GTPase.	PPP2R1A PPP2R1B	6.90e-04	32	42	2	17540176
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	MET PPP2R1A VAV3 CLK1 EML4 CYFIP2	7.41e-04	910	42	6	36736316
Pubmed	RUFY1 binds Arl8b and mediates endosome-to-TGN CI-M6PR retrieval for cargo sorting to lysosomes.	PPP2R1A PPP2R1B CCT4 XPO1	7.83e-04	344	42	4	36282215
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	CCT4 VAV3 PLCG2 XPO1	7.83e-04	344	42	4	30333137
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	MOB3B MET PPP2R1A CLASP2 MYO1D NOC2L EML4	8.00e-04	1284	42	7	17353931
Pubmed	Deployment of the human immunodeficiency virus type 1 protein arsenal: combating the host to enhance viral transcription and providing targets for therapeutic development.	PPP2R1A PPP2R1B	8.74e-04	36	42	2	22422068
Pubmed	Cell-Type-Specific Alternative Splicing Governs Cell Fate in the Developing Cerebral Cortex.	CLASP2 EML4	9.23e-04	37	42	2	27565344
Pubmed	Control of APC/C-dependent ubiquitin chain elongation by reversible phosphorylation.	PPP2R1A CCT4	9.23e-04	37	42	2	26811472
Pubmed	Identification of UHRF1/2 as new N-methylpurine DNA glycosylase-interacting proteins.	CLASP2 NOC2L	9.74e-04	38	42	2	23537643
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	PPP2R1A CCT4 CLASP2 XPO1 EML4	9.93e-04	638	42	5	33239621
Pubmed	Transcription factor Foxp3 and its protein partners form a complex regulatory network.	RGPD2 CCT4 CLASP2 NOC2L	1.03e-03	370	42	4	22922362
Pubmed	Interactome profiling reveals interaction of SARS-CoV-2 NSP13 with host factor STAT1 to suppress interferon signaling.	PPP2R1A CCT4 XPO1	1.07e-03	166	42	3	34687317
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	DOCK10 FRAS1 LLGL1 FHIP2A EML4	1.08e-03	650	42	5	38777146
Pubmed	Dynamic circadian protein-protein interaction networks predict temporal organization of cellular functions.	PPP2R1A PPP2R1B	1.08e-03	40	42	2	23555304
Pubmed	Deubiquitinating enzyme PSMD14 promotes tumor metastasis through stabilizing SNAIL in human esophageal squamous cell carcinoma.	PPP2R1A CCT4 XPO1 MYO1D	1.16e-03	383	42	4	29331416
Pubmed	Deubiquitinase FAM/USP9X interacts with the E3 ubiquitin ligase SMURF1 protein and protects it from ligase activity-dependent self-degradation.	PPP2R1A CCT4 CLASP2	1.18e-03	172	42	3	23184937
Pubmed	Merkel cell polyomavirus recruits MYCL to the EP400 complex to promote oncogenesis.	PPP2R1A PPP2R1B	1.19e-03	42	42	2	29028833
Interaction	SERTAD2 interactions	PPP2R1A PPP2R1B IGFN1 XPO1	1.15e-06	39	41	4	int:SERTAD2
Interaction	SH3BP2 interactions	MET VAV3 PLCG2 XPO1	2.69e-06	48	41	4	int:SH3BP2
Interaction	PPP4C interactions	PPP2R1A PPP2R1B CCT4 CLASP2 XPO1	9.89e-06	142	41	5	int:PPP4C
Interaction	NABP1 interactions	PPP2R1A XPO1 INTS11	1.97e-05	26	41	3	int:NABP1
Interaction	TRAF3IP3 interactions	PPP2R1A PPP2R1B MINAR1 XPO1	2.53e-05	84	41	4	int:TRAF3IP3
Interaction	PABIR1 interactions	PPP2R1A PPP2R1B XPO1	3.38e-05	31	41	3	int:PABIR1
Interaction	C11orf52 interactions	MET CCT4 XPO1 LLGL1 MYO1D NOC2L	3.67e-05	311	41	6	int:C11orf52
Interaction	FGFR1OP2 interactions	PPP2R1A PPP2R1B CCT4 CYFIP2	3.94e-05	94	41	4	int:FGFR1OP2
Interaction	FAM43A interactions	PPP2R1A PPP2R1B CLASP2	5.33e-05	36	41	3	int:FAM43A
Interaction	PTTG1 interactions	PPP2R1A PLCG2 XPO1 NOC2L	8.37e-05	114	41	4	int:PTTG1
Interaction	CDCA4 interactions	PPP2R1A PPP2R1B XPO1	1.05e-04	45	41	3	int:CDCA4
Interaction	TDRD9 interactions	PPP2R1A CLK1	1.44e-04	9	41	2	int:TDRD9
Interaction	SYK interactions	MET PPP2R1A PPP2R1B PLCG2 NOC2L	1.50e-04	251	41	5	int:SYK
Cytoband	2p15	CCT4 XPO1	3.74e-04	31	42	2	2p15
Cytoband	3p22.3	TRIM71 CLASP2	3.74e-04	31	42	2	3p22.3
Cytoband	Ensembl 112 genes in cytogenetic band chr2p15	CCT4 XPO1	7.54e-04	44	42	2	chr2p15
Cytoband	1p36.33	NOC2L INTS11	2.29e-03	77	42	2	1p36.33
GeneFamily	Protein phosphatase 2 scaffold subunits\|STRIPAK complex	PPP2R1A PPP2R1B	3.23e-06	2	33	2	1266
GeneFamily	Protein phosphatase catalytic subunits\|STRIPAK complex	PPP2R1A PPP2R1B	6.01e-04	20	33	2	1371
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	MYO1D CSRNP3 NOC2L	4.32e-03	181	33	3	694
GeneFamily	G protein-coupled receptors, Class A orphans	GPR161 GPR26	8.90e-03	78	33	2	262
GeneFamily	Ring finger proteins\|Tripartite motif containing\|ARF GTPase family	TRIM71 TRIM62	1.30e-02	95	33	2	59
GeneFamily	SH2 domain containing	VAV3 PLCG2	1.46e-02	101	33	2	741
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET VAV3 RHOBTB1 FAM162B EDNRA	6.55e-07	176	42	5	40993c41c1017b53039a337174fc56632b278609
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR161 MET VAV3 GPR26 EDNRA	9.55e-07	190	42	5	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 LY75 CYFIP2 WNT11	1.48e-05	158	42	4	90ca742739a208d457db087655ba3d1c18a9da57
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 LY75 CYFIP2 WNT11	1.55e-05	160	42	4	e9e52532131cdc3fb01e81cfc046e3f670cc8e75
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 LY75 CYFIP2 WNT11	1.55e-05	160	42	4	8dae9b0cf90a09acb196223f45a14680102630b2
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR161 MET VAV3 GPR26	1.92e-05	169	42	4	319cba07263bf41fcbcbfecd117f91b729394241
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET RHOBTB1 GPR26 FAM162B	1.97e-05	170	42	4	3174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET RHOBTB1 GPR26 FAM162B	1.97e-05	170	42	4	5de2f7d16a05af74ebfb1ca42d0f9c3c3524692d
ToppCell	Immune-dendritic_cell\|World / Lineage, Cell type, age group and donor	DOCK10 VAV3 ENOX1 CYFIP2	2.01e-05	171	42	4	6a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR161 RHOBTB1 GPR26 MYO1D	2.11e-05	173	42	4	8335b77f730ed43fc348a005566e73a103c6774b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET RHOBTB1 GPR26 FAM162B	2.16e-05	174	42	4	b3cd22e717d178269e6d5bd5ed7b2d945cd8ea25
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET RHOBTB1 FAM162B EDNRA	2.16e-05	174	42	4	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET VAV3 RHOBTB1 GPR26	2.31e-05	177	42	4	f902600c639087664316b3cf30cab243bc3d1c5c
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	GPR161 FBXL7 ENOX1 EDNRA	2.41e-05	179	42	4	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET VAV3 GPR26 EDNRA	2.46e-05	180	42	4	a407376209d80177bf7fc4200219030c83cb5f14
ToppCell	COVID-19-T_cells-Tregs\|COVID-19 / group, cell type (main and fine annotations)	DOCK10 VAV3 LY75 CYFIP2	2.52e-05	181	42	4	534659cf754326c6a73c0daa30e9d610612a0292
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 MET VAV3 EML4	2.57e-05	182	42	4	bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell	COVID-19-APC-like-Dendritic_cells\|COVID-19 / group, cell type (main and fine annotations)	DOCK10 VAV3 ENOX1 LY75	2.63e-05	183	42	4	703364836b42aa6ac6c68b42b700ac23c4a1afc7
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_CCDC168\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET VAV3 GPR26 EDNRA	2.74e-05	185	42	4	5a0340c25196453f19e424d346efbf66d2c53ac3
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	MOB3B ENOX1 FAM162B EDNRA	2.80e-05	186	42	4	cb1fc4b9140666b43415e21c9b434dc9b144e9d0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1-6_LAMP5_CA13_(Lamp5_Lhx6_1)\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 GPR161 VAV3 FBXL7	2.80e-05	186	42	4	77592a6397b44b2b59a4fc39d7224dd95343efe6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 MYO1D FAM162B EDNRA	2.86e-05	187	42	4	15d6e158562d7d85af3ceaf955439b379c8fce81
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 MYO1D FAM162B EDNRA	2.86e-05	187	42	4	f62074b631fd45ad299c69d71b09267b04d656ee
ToppCell	PSB-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	MOB3B PLCG2 EDNRA WNT11	3.10e-05	191	42	4	8f4637e801554e2343b974fe7794f01dd2151418
ToppCell	Control-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	HAPLN2 MYO1D EDNRA CYFIP2	3.10e-05	191	42	4	2da83c493e60ad0278848957645277d76737a188
ToppCell	human_hepatoblastoma-Hepatic_Stellate_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	MOB3B ENOX1 FAM162B EDNRA	3.10e-05	191	42	4	78c3c2fdb68c3407f2436f90e1e6a780bbf8b79e
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	RGPD2 PLCG2 CLK1 EML4	3.10e-05	191	42	4	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	renal_papilla_nuclei-Adult_normal_reference\|renal_papilla_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 FBXL7 CSRNP3 CYFIP2	3.17e-05	192	42	4	6c106b91e46eabbe686a52a65a9c94ad9cbe9390
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET VAV3 GPR26 EDNRA	3.17e-05	192	42	4	25460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	DOCK10 CLASP2 CLK1 EML4	3.17e-05	192	42	4	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MOB3B MET MYO1D SLC15A1	3.37e-05	195	42	4	938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MOB3B MET MYO1D SLC15A1	3.37e-05	195	42	4	d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)\|Adult / Lineage, Cell type, age group and donor	DOCK10 MOB3B VAV3 EML4	3.37e-05	195	42	4	55e25f702af19146a161861cfd15f40bbda1dc35
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GPR161 MET VAV3 GPR26	3.37e-05	195	42	4	787e95fb59c40bba784544b662fac37606ae1427
ToppCell	ILEUM-non-inflamed-(8)_Pericytes\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HAPLN2 CSRNP3 FAM162B EDNRA	3.43e-05	196	42	4	b98fe1519e420d8b03c66e164bf4544f3dbb2e44
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MET FRAS1 VAV3 CYFIP2	3.43e-05	196	42	4	c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCell	ILEUM-inflamed-(8)_Pericytes\|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HAPLN2 CSRNP3 FAM162B EDNRA	3.50e-05	197	42	4	e04ac8575f66d798ddf2fd6d55d397a163b40732
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	DOCK10 MOB3B VAV3 EML4	3.57e-05	198	42	4	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	Adult-Immune-alveolar_macrophage_(MARCO_positive)-D231\|Adult / Lineage, Cell type, age group and donor	DOCK10 MOB3B VAV3 EML4	3.57e-05	198	42	4	79a415e19cedde13a88f5043d71557363f102322
ToppCell	Fetal_29-31_weeks\|World / Lineage, Cell type, age group and donor	FRAS1 FBXL7 ENOX1 EDNRA	3.64e-05	199	42	4	5b9d355795dd03a22f0961dfd143425c367a4654
ToppCell	Macroglial-Oligodendrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DOCK10 HAPLN2 MOB3B MYO1D	3.72e-05	200	42	4	4dbac2f2587e87ca5a0622f50439bb5447e93c7f
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MOB3B MET RHOBTB1 FAM162B	3.72e-05	200	42	4	f75d95376a340d467c4392b872b2a2dbdd184556
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1--L3-4\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MOB3B MET RHOBTB1 FAM162B	3.72e-05	200	42	4	47791c93d03ee17c1ce17e27f075be4fc6f2590e
ToppCell	Neuronal-Excitatory-eC(RORB)-eC_1-CARM1P1-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	MOB3B MET RHOBTB1 FAM162B	3.72e-05	200	42	4	fae26560ba3b0b638b6bcf92f05330824b31d21b
ToppCell	Macroglial-Oligodendrocytes-OPALIN---\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DOCK10 HAPLN2 MOB3B MYO1D	3.72e-05	200	42	4	1314664c1721e9ecb1e2c3482a039044b0fe50a9
ToppCell	Macroglial-Oligodendrocytes-OPALIN-\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DOCK10 HAPLN2 MOB3B MYO1D	3.72e-05	200	42	4	8b229f095fc113aecfc94b64862a9e0fdcc363ce
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR-\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DOCK10 GPR161 FRAS1 FBXL7	3.72e-05	200	42	4	d416a7be1a4e6232fb58a9687774da24821f1fdd
ToppCell	Macroglial-Oligodendrocytes-OPALIN----L1-6\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DOCK10 HAPLN2 MOB3B MYO1D	3.72e-05	200	42	4	272909f4354f3ae22e2b2f8f35970e6b0e92cfe2
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DOCK10 GPR161 FRAS1 FBXL7	3.72e-05	200	42	4	862db57d043bdf3cb059fbfc8b29bc1eafdf64ec
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-B-B_cell-B_naive\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 VAV3 PLCG2 CYFIP2	3.72e-05	200	42	4	4f7be296be0cd54cfc62cc93263fde26210c61f4
ToppCell	Macroglial-Oligodendrocytes-OPALIN--\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DOCK10 HAPLN2 MOB3B MYO1D	3.72e-05	200	42	4	26b989e30bbbaf30904ced03f6aae3dea25c732c
ToppCell	Macroglial-Oligodendrocytes-OPALIN\|Macroglial / cells hierarchy compared to all cells using T-Statistic	DOCK10 HAPLN2 MOB3B MYO1D	3.72e-05	200	42	4	5f75a9b8bcd49d9bbb1e9ce2de730eaec96369ca
ToppCell	Neuronal-Inhibitory-iA-iA_1(SST_PAX6)-NMBR--L1\|Neuronal / cells hierarchy compared to all cells using T-Statistic	DOCK10 GPR161 FRAS1 FBXL7	3.72e-05	200	42	4	a91345f268f13170c27309333603eb82400c9947
ToppCell	facs-Heart-Unknown-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 IGFN1 GPR26	3.16e-04	141	42	3	4aa4b3476dc5abefbd348353cfe711cd5fe3d52f
ToppCell	facs-Heart-Unknown-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 IGFN1 GPR26	3.16e-04	141	42	3	e40c6f1b7fbaa46b3eaa55f1b37ef360b04370a8
ToppCell	facs-Heart-Unknown-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 IGFN1 GPR26	3.23e-04	142	42	3	759fbbd15b4fb313bd6269b7f087edafebd530ef
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FBXL7 EDNRA WNT11	3.36e-04	144	42	3	1c001a5a3bbe4ecbce8305f8b260e933033550dd
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nptxr\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	FRAS1 IGFN1 GPR26	3.64e-04	148	42	3	223d6a640f3c34e73646a615593b9c0b4a4cbd6f
ToppCell	368C-Lymphocytic-CD4_T-cell-Treg_cell_1\|368C / Donor, Lineage, Cell class and subclass (all cells)	RGPD2 LY75 CYFIP2	3.64e-04	148	42	3	80470353e12599440f711b6e107730763376d04d
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-7\|TCGA-Bladder / Sample_Type by Project: Shred V9	DOCK10 IGFN1 CD33	3.79e-04	150	42	3	3ab17045b2c43bb4f0ebba6aa0cfb22e076a24f9
ToppCell	Fetal_29-31_weeks-Immune-dendritic_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	VAV3 PLCG2 CYFIP2	4.17e-04	155	42	3	9f937ae48767fdcf1a944af4de0530d9c0ab441d
ToppCell	COVID-19_Moderate-multiplets\|World / disease group, cell group and cell class	PLCG2 ENOX1 EML4	4.25e-04	156	42	3	afdc025fa75e7926b1cc182c4a33654a2186abb1
ToppCell	COVID-19-Myeloid-Dendritic_cells\|COVID-19 / group, cell type (main and fine annotations)	DOCK10 MOB3B VAV3	4.25e-04	156	42	3	a07a9096799e4ba663841c70035b4b32c1fda4f9
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 PLCG2 EDNRA	4.33e-04	157	42	3	c17c5c01fcb65c453690c265ec4f300ecdfefd34
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D FAM162B EDNRA	4.49e-04	159	42	3	5ca96db4281abb5f646150ccf36adc66ab201c78
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK10 CD33 TRIM62	4.49e-04	159	42	3	0c2437da5443fc3aff66f8ef311f02aa434a1fb0
ToppCell	Posterior_cortex\|World / BrainAtlas - Mouse McCarroll V32	MET IGFN1 GPR26	4.49e-04	159	42	3	18e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	VAV3 ENOX1 CYFIP2	4.58e-04	160	42	3	03b88dc7ad41c6ae443cab7e77ec666340bf432e
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2\|Thalamus / BrainAtlas - Mouse McCarroll V32	TRPM1 GPR26 WNT11	4.58e-04	160	42	3	fe5fb0e7a79862f63529721f0a82f4f6d231d3ca
ToppCell	Thalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7\|Thalamus / BrainAtlas - Mouse McCarroll V32	TRPM1 GPR26 WNT11	4.58e-04	160	42	3	7d34159363d274019e14549d1186c629ce990691
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	MET FRAS1 GPR26	4.66e-04	161	42	3	ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCell	E18.5-samps-Myeloid-Macrophage-macrophage_-_intermediate_-_unactivated\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DOCK10 PLCG2 CD33	4.75e-04	162	42	3	60d3fe1f5cec4285b8774ff078ebcc6bfaec26ed
ToppCell	E18.5-samps-Myeloid\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DOCK10 PLCG2 CD33	4.75e-04	162	42	3	18e4a807e25f754a69e9eaaddfde40f8de9b8512
ToppCell	E18.5-samps-Myeloid-Macrophage\|E18.5-samps / Age Group, Lineage, Cell class and subclass	DOCK10 PLCG2 CD33	4.75e-04	162	42	3	0970e4eda60e3f015335e2726e6d565fb2f43372
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	DOCK10 CLK1 EML4	4.75e-04	162	42	3	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical-aged\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 MYO1D EDNRA	4.92e-04	164	42	3	f6a961fa2002da7d9679f32af99e1314c0593ef9
ToppCell	PND01-03-samps-Myeloid-Macrophage\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	DOCK10 LY75 CD33	4.92e-04	164	42	3	49733a9d3d95f05056b5b01916060ff20a8de3cf
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Lymphocytic-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 ENOX1 EDNRA	5.01e-04	165	42	3	475905d608fac628960188ae4a18010b8097417e
ToppCell	Control-B_cells-Activated_B_cells\|Control / group, cell type (main and fine annotations)	DOCK10 PLCG2 CYFIP2	5.27e-04	168	42	3	a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK10 CD33 TRIM62	5.37e-04	169	42	3	305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCell	BL-critical-LOC-Epithelial-Ionocyte\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CSRNP3 EDNRA WNT11	5.46e-04	170	42	3	b465df2dac6b4e98b4ede6ad0c6347656757885c
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D FAM162B EDNRA	5.46e-04	170	42	3	876b84740e15399bfff2b9c7f0b80fd759bbdb3f
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOB3B PPP2R1B CYFIP2	5.46e-04	170	42	3	8e774af244cfe787fa0ea2b6be0c3c2d00bfe4fc
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MYO1D FAM162B EDNRA	5.46e-04	170	42	3	1f8738acf439d893880db7e1fdc9b3615ca00c39
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MOB3B PPP2R1B CYFIP2	5.46e-04	170	42	3	f5140eb9313c0d1bb31f8a761d9c062c56733a61
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGFN1 FAM162B EDNRA	5.46e-04	170	42	3	d9ed257d0938442d0bb280e4c4b0c9b657511b46
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_ACHE\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DOCK10 FAM162B EDNRA	5.46e-04	170	42	3	36dbbdb13f69307afd2122ff051b2980850c1f00
ToppCell	Control-Fibroblasts-Pericytes\|Control / group, cell type (main and fine annotations)	ENOX1 FAM162B EDNRA	5.55e-04	171	42	3	080003f698f867935c2bfc55d241d3650f45a0ab
ToppCell	LV-13._Vascular_Smooth_Muscle\|LV / Chamber and Cluster_Paper	DOCK10 MYO1D EDNRA	5.55e-04	171	42	3	e99ecae66530d1ae09330cee408c8f3950b87e67
ToppCell	metastatic_Brain-Myeloid_cells-CD207+CD1a+_LCs\|Myeloid_cells / Location, Cell class and cell subclass	MOB3B MYO1D EDNRA	5.65e-04	172	42	3	38d17e769fe8eac8b57b820490d4ddd969243ee7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 FAM162B EDNRA	5.65e-04	172	42	3	553701349444eb366df3c11f54bb093434f153c6
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-angiogenic_pericyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	IGFN1 FAM162B EDNRA	5.65e-04	172	42	3	107417cfab7775bc1f80807115047abfb50b7a7e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK10 FAM162B EDNRA	5.65e-04	172	42	3	08a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FBXL7 EDNRA WNT11	5.74e-04	173	42	3	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	facs-Aorta-Heart-3m-Myeloid\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 PLCG2 CYFIP2	5.74e-04	173	42	3	513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCell	facs-Spleen-nan-24m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEFF1 MET FRAS1	5.74e-04	173	42	3	e07e126e9dac6f1160cb3191d2e8374f39155d0d
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MET RHOBTB1 FAM162B	5.74e-04	173	42	3	9a2d42f8d9cb834856522661d524abb91c4637c5
ToppCell	facs-Trachea-nan-3m-Myeloid-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 PLCG2 CD33	5.74e-04	173	42	3	e4eb2ac2cee16bfa8eabc938f8030ee161c972c5
ToppCell	facs-Trachea-nan-3m-Myeloid\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 PLCG2 CD33	5.74e-04	173	42	3	371515471459307a3b2adce735263b4aac828956
ToppCell	facs-Trachea-nan-3m-Myeloid-macrophage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK10 PLCG2 CD33	5.74e-04	173	42	3	4e9b6c71030ae0d63d54e7255e4a10b25970fcc4
Drug	endothall	MET PPP2R1A PPP2R1B EDNRA	5.64e-07	36	42	4	CID000003225
Drug	Furaltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A	MOB3B PPP2R1B FBXL7 EML4 EDNRA	2.81e-05	194	42	5	3932_DN
Drug	Betamethasone [378-44-9]; Down 200; 10.2uM; PC3; HT_HG-U133A	DOCK10 VAV3 FBXL7 MYO1D TRIM62	2.95e-05	196	42	5	6728_DN
Drug	Scopolamine hydrochloride [55-16-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A	MOB3B PPP2R1B FRAS1 ENOX1 EDNRA	3.02e-05	197	42	5	3357_UP
Drug	Biperiden hydrochloride [1235-82-1]; Up 200; 11.4uM; PC3; HT_HG-U133A	DOCK10 MET PPP2R1A LLGL1 SLC15A1	3.10e-05	198	42	5	4684_UP
Disease	sleep latency	FRAS1 VAV3	1.28e-03	37	42	2	EFO_0005280
Disease	Facial wrinkling	PPP2R1B VAV3	1.28e-03	37	42	2	HP_0009762
Disease	Congenital small ears	FRAS1 EDNRA	1.57e-03	41	42	2	C0152423
Disease	pancreatic carcinoma	MYO1D NOC2L EDNRA	1.95e-03	174	42	3	EFO_0002618
Disease	Chronic Lymphocytic Leukemia	PLCG2 XPO1	2.80e-03	55	42	2	C0023434
Disease	chronic obstructive pulmonary disease	DOCK10 FRAS1 LLGL1 EML4 TRIM62	2.83e-03	688	42	5	EFO_0000341
Disease	IGA glomerulonephritis	DOCK10 VAV3	3.11e-03	58	42	2	EFO_0004194

Protein segments in the cluster

Peptide	Gene	Start	Entry
AEVRAAASHKVKEFC	PPP2R1A	296	P30153
CEAEVRAAAAHKVKE	PPP2R1B	306	P30154
EHLKQRREVAKTVFC	EDNRA	296	P25101
RHVAVKIVKNVDRYC	CLK1	186	P49759
AHEGCRVRKVALATF	LLGL1	851	Q15334
CKKILCRLFRVFVHV	MOB3B	151	Q86TA1
RFHVRCVAKAVDKVG	FRAS1	3266	Q86XX4
AVTARHKKALEEREC	TRIM71	366	Q2Q1W2
AHAACRRRGAVVAKV	HAPLN2	261	Q9GZV7
CRERDFLKKVHETVE	INTS11	216	Q5TA45
CLIFFIVKTHRRKAA	CD33	276	P20138
REKRLRTKNVHFSCV	CSRNP3	56	Q8WYN3
LKVARFHCKRIDVIT	GPR26	196	Q8NDV2
CYKVFHAERIVRKRN	LY75	656	O60449
AITFRARGKVKHCRI	PLCG2	681	P16885
KAIERFCSEVKRLCH	CYFIP2	131	Q96F07
VLAFLVLSRVCRHKK	NOC2L	311	Q9Y3T9
FVFKTRACKERTVHE	DOCK10	951	Q96BY6
VSVEALRFVKRHCKR	FBXL7	466	Q9UJT9
IFRVARVKARKVHCG	GPR161	211	Q8N6U8
GKEVAHSFRIRVAAC	IGFN1	1026	Q86VF2
RKVIAVADDFCKVHL	EML4	801	Q9HC35
AARKRKFHVIVAECA	EIF2B2	181	P49770
KTAAVALAKAVHERF	FHIP2A	376	Q5W0V3
AKRAVHLSDVVLRFC	PEX11B	71	O96011
VAKCIGFAIKNRFRH	SLC15A1	236	P46059
IRKSKKNFCHIRFAE	ENOX1	171	Q8TC92
CFAVIVSAKRAVERH	FAM162B	121	Q5T6X4
EAEFRRAKVCKIAAL	MINAR1	881	Q9UPX6
RAKVCKIAALIAAAA	MINAR1	886	Q9UPX6
ASKKFVHRDLAARNC	MET	1196	P08581
VEKRFVHEAEKFRPC	SAXO1	216	Q8IYX7
SNKRLKDAVARCHEA	RGPD2	176	P0DJD1
HDALCVIRCLVKKRA	CCT4	406	P50991
AFHVRKANRIKECLS	RHOBTB1	466	O94844
VRKACVFCLVAVHAV	CLASP2	1236	O75122
DTFIKIAQKCRRHFV	XPO1	586	O14980
CLKLAVAAKHRDFIA	TRPM1	711	Q7Z4N2
HAAREVMKACRRAFA	WNT11	71	O96014
ECFLRRAACKHQKEI	TMEFF1	121	Q8IYR6
RAACKHQKEITVIAR	TMEFF1	126	Q8IYR6
ARRAARPCQAHDKVK	TRIM62	86	Q9BVG3
HIFLFDLAVIVCKRK	VAV3	421	Q9UKW4
CHVRKVNRFSKVEDR	MYO1D	861	O94832