Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionGTPase activator activity

RAP1GAP ARHGAP40 TAGAP STXBP5L SIPA1L3 BCR ANKRD27 ARHGAP6 LLGL2 PLCB1 ARHGAP25

2.26e-0527916611GO:0005096
GeneOntologyMolecularFunctiontranscription corepressor activity

CASP8AP2 TBL1Y BCORL1 CBX4 PRDM8 SNW1 YAP1 RERE LCOR

1.31e-042291669GO:0003714
GeneOntologyMolecularFunctionnucleoside-triphosphatase regulator activity

RAP1GAP ARHGAP40 NET1 TAGAP STXBP5L SIPA1L3 BCR ANKRD27 ARHGAP6 LLGL2 PLEKHG3 PLCB1 ARHGAP25

3.30e-0450716613GO:0060589
GeneOntologyMolecularFunctionGTPase regulator activity

RAP1GAP ARHGAP40 NET1 TAGAP STXBP5L SIPA1L3 BCR ANKRD27 ARHGAP6 LLGL2 PLEKHG3 PLCB1 ARHGAP25

3.30e-0450716613GO:0030695
DomainPeptidase_M43

PAPPA2 PAPPA

7.39e-0521612IPR008754
DomainPeptidase_M43

PAPPA2 PAPPA

7.39e-0521612PF05572
DomainZnF_C2HC

FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10

1.10e-04551615SM00343
DomainZnf_CCHC

FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A10

1.10e-04551615IPR001878
DomainCAC1F_C

CACNA1C CACNA1F

2.20e-0431612IPR031688
DomainMyxo_disulph_rpt

PAPPA2 PAPPA

2.20e-0431612IPR011936
DomainCAC1F_C

CACNA1C CACNA1F

2.20e-0431612PF16885
DomainLLGL

STXBP5L LLGL2

4.38e-0441612PF08366
DomainLamGL

PAPPA2 PAPPA

4.38e-0441612SM00560
DomainLamG-like

PAPPA2 PAPPA

4.38e-0441612IPR006558
DomainVDCC_L_a1su

CACNA1C CACNA1F

4.38e-0441612IPR005446
DomainLethal2_giant

STXBP5L LLGL2

4.38e-0441612IPR000664
DomainLLGL2

STXBP5L LLGL2

4.38e-0441612IPR013577
Pubmed

Characterization and evolution of the novel gene family FAM90A in primates originated by multiple duplication and rearrangement events.

FAM90A17 FAM90A19 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

3.20e-1325173817684299
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TCF20 TBL1Y NHSL2 SYNE1 SIPA1L3 APC2 SH3KBP1 ANKS1B DDN ZNF318 PEX5L BCR CCDC177 ADAM22 STOX2 PBRM1 SNW1 DST CASKIN1 SVIL ZNF516 PLCB1 NAV1 AFDN HOMER2 PRRC2B SMG6

3.80e-139631732728671696
Pubmed

Analysis of the multi-copy gene family FAM90A as a copy number variant in different ethnic backgrounds.

FAM90A17 FAM90A19 FAM90A7 FAM90A9 FAM90A8 FAM90A16 FAM90A10

1.53e-1123173718602769
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

RAP1GAP TCF20 NET1 CEP162 POTEF SIPA1L3 CBX4 BCR ANKRD27 USP31 NHSL1 STOX2 DST SLF2 YAP1 PLEKHG3 STARD9 SVIL NAV1 AFDN BOD1L1

2.33e-098611732136931259
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

WASHC2C VWA8 SIPA1L3 GPATCH8 ATP10A PLEKHG3 PLCB1 KATNIP PRRC2B

3.02e-0910517399628581
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WASHC2C TCF20 TRO SYNE1 RBM10 DDN GPATCH8 USP31 STARD9 NAV1 KATNIP BOD1L1 RERE PRRC2B

1.93e-084071731412693553
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

CASP8AP2 WASHC2C BCORL1 RNF40 TACC2 ZNF318 CBX4 MORC4 BCR POTEE SLF2 YAP1 ZNF516 NAV1 CFAP44 PRRC2B

4.75e-085881731638580884
Pubmed

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

COL7A1 POTEF SIPA1L3 DYNC2I1 POTEE TTBK2 SLF2 KATNIP TGS1

6.50e-08149173922664934
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

CACNA1C TIGAR STXBP5L SDCCAG8 SIPA1L3 DYNC2I1 CHD9 PPHLN1 LARP4 BCR TRRAP ATP10A CASZ1 PTK7 ARHGAP6 PLEKHG3 EEPD1 NAV1 AFF1 KATNIP BOD1L1 RERE LCOR DAGLA SMG6

1.06e-0714891732528611215
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

TCF20 ING1 RBM10 RNF40 MORC4 CASZ1 PBRM1 YAP1 RERE ZNF281 PRRC2B

1.16e-072681731133640491
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

CASP8AP2 TCF20 ING1 FOS RBM10 BCORL1 NUP43 PPHLN1 RNF40 ZNF318 CBX4 GPATCH8 TRRAP CASZ1 ARL6IP4 PBRM1 SNW1 DST SLF2 YAP1 ZNF281 LCOR C1orf174

1.33e-0712941732330804502
Pubmed

Human transcription factor protein interaction networks.

FLG TCF20 ING1 TBL1Y FOS RBM10 SH3KBP1 BCORL1 ZNF318 GPATCH8 MORC4 LARP4 TRRAP PBRM1 SNW1 DST ZFHX4 YAP1 SVIL ZNF516 PAX2 RERE ZNF281 PRRC2B

1.95e-0714291732435140242
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

CASP8AP2 TCF20 BCORL1 COPG2 RNF40 ZNF318 MORC4 BCR DST ZFHX4 ZNF516 NAV1 RERE

2.01e-074181731334709266
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

CASP8AP2 VWA8 CEP162 RNF40 BCR ANKRD27 STOX2 DST CASKIN1 ZNF516 PLCB1 LCOR DAGLA SMG6

4.73e-075291731414621295
Pubmed

Gene expression in the developing mouse retina by EST sequencing and microarray analysis.

CASP8AP2 PRSS23 DST AJAP1 ZFHX4 AFF1 AFDN DAGLA

6.07e-07142173811812828
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RAP1GAP SIPA1L3 TOGARAM1 GPRIN3 ATP10A CASZ1 CCDC85A AMIGO1 TRPM3 PLEKHG3 EEPD1 ARHGAP25 FHDC1

1.28e-064931731315368895
Pubmed

Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.

TCF20 CHD9 PPHLN1 ZNF318 CBX4 SNW1 SLF2 ZNF516 ZNF281

1.87e-06222173937071664
Pubmed

A synaptic temperature sensor for body cooling.

TRPV1 FOS TRPM3

2.39e-066173334672983
Pubmed

High-Confidence Interactome for RNF41 Built on Multiple Orthogonal Assays.

SIPA1L3 TACC2 NAV1 ZNF281 HOMER2

5.08e-0650173529560723
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

NUP85 VWA8 SIPA1L3 RNF40 BCR TRRAP CASZ1 NHSL1 HEG1 LLGL2 DST CASKIN1 ZNF516 SCN8A NAV1 PAX2 PRRC2B SMG6

1.11e-0511051731835748872
Pubmed

Interaction network of human early embryonic transcription factors.

TCF20 BCORL1 NUP43 MORC4 PBRM1 ZFHX4 ZNF516 RERE ZNF281 PRRC2B

1.14e-053511731038297188
Pubmed

Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.

TCF20 NUP85 SYNE1 SH3KBP1 ANO1 GPATCH8 TTLL6

1.18e-05152173734299191
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

TCF20 RBM10 RNF40 TRRAP CASZ1 PBRM1 SNW1 RERE

1.56e-05220173835785414
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

CASP8AP2 SYNE1 SIPA1L3 TOGARAM1 DST PLCB1 DAGLA SMG6

1.83e-05225173812168954
Pubmed

Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.

TCEANC FAM90A17 FAM90A19 FAM90A7 FAM90A9 FAM90A8 FAM90A10

1.93e-05164173722967998
Pubmed

Evolutionary diversification of the BetaM interactome acquired through co-option of the ATP1B4 gene in placental mammals.

TOR1AIP2 SYNE1 SNW1

1.94e-0511173326939788
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

TCF20 CAMLG DYNC2I1 PPHLN1 RNF40 GPATCH8 LARP4 BCR VIPAS39 YAP1 ARNT2 NAV1 BOD1L1 TGS1

1.99e-057331731434672954
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

WASHC2C NUP85 SYNE1 SIPA1L3 SH3KBP1 CEP170P1 NUP43 DYNC2I1 TACC2 FANCE TTBK2 STOX2 LLGL2 PBRM1 SNW1 SVIL PRRC2B TGS1

2.00e-0511551731820360068
Pubmed

SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.

WASHC2C NUP85 NET1 VWA8 RBM10 NUP43 PPHLN1 ANKRD27 YAP1 AFDN

2.16e-053781731034315543
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

GATD3 PMS2 RAP1GAP SYNE1 CAMLG SIPA1L3 APC2 ANKS1B NUP43 DYNC2I1 CHD9 RNF40 ADAM22 CCDC85A DST SLF2 RETREG1 AFDN LCOR

2.40e-0512851731935914814
Pubmed

Heterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defects.

YAP1 PAX2

2.46e-052173224462371
Pubmed

A primate-specific POTE-actin fusion protein plays a role in apoptosis.

POTEF POTEE

2.46e-052173219669888
Pubmed

Pregnancy-associated plasma protein-A2 (PAPP-A2): tissue expression and biological consequences of gene knockout in mice.

PAPPA2 PAPPA

2.46e-052173221586553
Pubmed

The Catalytic Efficiency of Lipin 1β Increases by Physically Interacting with the Proto-oncoprotein c-Fos.

FOS LPIN1

2.46e-052173226475860
Pubmed

Mutational analysis of the proteolytic domain of pregnancy-associated plasma protein-A (PAPP-A): classification as a metzincin.

PAPPA2 PAPPA

2.46e-052173211513734
Pubmed

Nuclear phospholipase C-β1 and diacylglycerol LIPASE-α in brain cortical neurons.

PLCB1 DAGLA

2.46e-052173224076015
Pubmed

CIN85 is localized at synapses and forms a complex with S-SCAM via dendrin.

SH3KBP1 DDN

2.46e-052173216751601
Pubmed

Mouse models of congenital cataract.

PITX3 PAX2

2.46e-052173210627821
Pubmed

Pregnancy associated plasma protein-A as a prognostic biomarker of all-cause mortality and cardiovascular events in patients presenting with chest pain: a systematic review.

PAPPA2 PAPPA

2.46e-052173229144175
Pubmed

Yes-associated protein (YAP) promotes cell survival by inhibiting proapoptotic dendrin signaling.

DDN YAP1

2.46e-052173223667252
Pubmed

Diacylglycerol lipase alpha promotes hepatocellular carcinoma progression and induces lenvatinib resistance by enhancing YAP activity.

YAP1 DAGLA

2.46e-052173237414748
Pubmed

Pain-enhancing mechanism through interaction between TRPV1 and anoctamin 1 in sensory neurons.

TRPV1 ANO1

2.46e-052173225848051
Pubmed

Association of CACNA1C and SYNE1 in offspring of patients with psychiatric disorders.

CACNA1C SYNE1

2.46e-052173227620326
Pubmed

Senescent cells perturb intestinal stem cell differentiation through Ptk7 induced noncanonical Wnt and YAP signaling.

PTK7 YAP1

2.46e-052173236631445
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

TCF20 ING1 EML4 RBM10 BCORL1 COPG2 PPHLN1 ZNF318 CBX4 SNW1 SLF2 AFDN BOD1L1 ZNF281 LCOR C1orf174

2.47e-059541731636373674
Pubmed

USP7 Regulates Cytokinesis through FBXO38 and KIF20B.

RNF40 GPATCH8 MORC4 TRRAP ZNF281 PRRC2B

2.62e-05116173630804394
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

CACNA1C FLG TTC24 NUP85 NHSL2 MYH7B TRO POTEF SYNE1 SIPA1L3 ANKS1B ZNF318 PTK7 POTEE PRDM8 DST STARD9 RETREG1 BOD1L1 PRRC2B

3.57e-0514421732035575683
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

WASHC2C TCF20 EML4 RBM10 ZNF318 GPATCH8 TRRAP MYO3A YAP1 SVIL ZNF516 AFF1 AFDN RERE

3.60e-057741731415302935
Pubmed

Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.

SYNE1 SH3KBP1 ANKS1B DDN ADAM22 CASKIN1 PLCB1 HOMER2

3.99e-05251173827507650
Pubmed

Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.

RBM10 SIPA1L3 ZNF318 SNW1 SVIL NAV1 ZNF281

4.02e-05184173732908313
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

POTEF SYNE1 RBM10 TRRAP DST PLCB1 CFAP44

4.46e-05187173726460568
Pubmed

Genomic analysis of mouse retinal development.

TOR1AIP2 PMS2 WASHC2C EML4 TACC2 PEX5L CASZ1 FANCE PRDM8 VIPAS39 DST ZFHX4 TRPM3 RP1L1 KATNIP PRRC2B

4.65e-0510061731615226823
Pubmed

Monoallelic yet combinatorial expression of variable exons of the protocadherin-alpha gene cluster in single neurons.

PCDHA7 PCDHA6 PCDHA1

5.27e-0515173315640798
Pubmed

Coordinated histone modifications mediated by a CtBP co-repressor complex.

CBX4 ZNF516 LCOR

5.27e-0515173312700765
Pubmed

EZH2 and BCL6 Cooperate to Assemble CBX8-BCOR Complex to Repress Bivalent Promoters, Mediate Germinal Center Formation and Lymphomagenesis.

BCORL1 CBX4 MORC4 ZNF281

6.87e-0544173427505670
Pubmed

Solution structure of AF-6 PDZ domain and its interaction with the C-terminal peptides from Neurexin and Bcr.

BCR AFDN

7.36e-053173215684424
Pubmed

The Bcr kinase downregulates Ras signaling by phosphorylating AF-6 and binding to its PDZ domain.

BCR AFDN

7.36e-053173212808105
Pubmed

Co- and post-transcriptional regulation of Rbm5 and Rbm10 in mouse cells as evidenced by tissue-specific, developmental and disease-associated variation of splice variant and protein expression levels.

RBM10 DST

7.36e-053173226784654
Pubmed

CREB, AP-1, ternary complex factors and MAP kinases connect transient receptor potential melastatin-3 (TRPM3) channel stimulation with increased c-Fos expression.

FOS TRPM3

7.36e-053173226493679
Pubmed

Degradation of Intrinsically Disordered Proteins by the NADH 26S Proteasome.

FOS YAP1

7.36e-053173233297334
Pubmed

The Barrier Molecules Junction Plakoglobin, Filaggrin, and Dystonin Play Roles in Melanoma Growth and Angiogenesis.

FLG DST

7.36e-053173231425296
Pubmed

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.

CACNA1C SDCCAG8

7.36e-053173222614287
Pubmed

Increased levels of pregnancy-associated plasma protein-A2 in the serum of pre-eclamptic patients.

PAPPA2 PAPPA

7.36e-053173218805800
Pubmed

TRPM3 is a nociceptor channel involved in the detection of noxious heat.

TRPV1 TRPM3

7.36e-053173221555074
Pubmed

Placental expression of PAPPA, PAPPA-2 and PLAC-1 in pregnacies is associated with FGR.

PAPPA2 PAPPA

7.36e-053173229532882
Pubmed

Altered placental expression of PAPPA2 does not affect birth weight in mice.

PAPPA2 PAPPA

7.36e-053173220642865
Pubmed

Crystal structure of human nuclear pore complex component NUP43.

NUP85 NUP43

7.36e-053173226391640
Pubmed

Evolution and expression of chimeric POTE-actin genes in the human genome.

POTEF POTEE

7.36e-053173217101985
Pubmed

Upregulation of TRPM3 in nociceptors innervating inflamed tissue.

TRPV1 TRPM3

7.36e-053173232880575
Pubmed

A TRP channel trio mediates acute noxious heat sensing.

TRPV1 TRPM3

7.36e-053173229539642
Pubmed

Activation of TRPM3 by a potent synthetic ligand reveals a role in peptide release.

TRPV1 TRPM3

7.36e-053173225733887
Pubmed

The calcium-activated chloride channel anoctamin 1 acts as a heat sensor in nociceptive neurons.

TRPV1 ANO1

7.36e-053173222634729
Pubmed

Alpha protocadherins and Pyk2 kinase regulate cortical neuron migration and cytoskeletal dynamics via Rac1 GTPase and WAVE complex in mice.

PCDHA7 PCDHA6 PCDHA1

7.81e-0517173329911975
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

TOR1AIP2 TCF20 BCORL1 MORC4 CASZ1 CCDC85A TTBK2 PBRM1 ZNF516 PLCB1 ZNF281 PRRC2B

9.14e-056381731231182584
Pubmed

Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia.

TRPV1 ANO1 TRPM3

9.34e-0518173331911949
Pubmed

CNR/Pcdhalpha family in subplate neurons, and developing cortical connectivity.

PCDHA7 PCDHA6 PCDHA1

9.34e-0518173315570159
Pubmed

Genomic organization of the family of CNR cadherin genes in mice and humans.

PCDHA7 PCDHA6 PCDHA1

9.34e-0518173310662547
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

RAP1GAP NUP85 EML4 BCR ANKRD27 PTK7 CDC45 LPIN1 LLGL2 DST AFDN PRRC2B

1.09e-046501731238777146
Pubmed

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

CACNA1C SYNE1 ARNT2

1.11e-0419173318711365
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TOR1AIP2 PMS2 WASHC2C NET1 TAGAP CEP162 CAMLG COPG2 TACC2 ZNF318 GPATCH8 TUB TTBK2 AFF1 BOD1L1 TGS1

1.11e-0410841731611544199
Pubmed

Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.

CASP8AP2 NHSL1 STOX2 STARD9 CASKIN1 BOD1L1

1.22e-04153173610718198
Pubmed

Loss of inhibitory interneurons in the dorsal spinal cord and elevated itch in Bhlhb5 mutant mice.

FOS PRDM8 PAX2

1.30e-0420173320346763
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

WASHC2C GPRIN3 RNF40 CCDC177 TUB PBRM1 CASKIN1 SCN8A PLCB1 PRRC2B

1.44e-044751731031040226
Pubmed

ANO1 in intramuscular interstitial cells of Cajal plays a key role in the generation of slow waves and tone in the internal anal sphincter.

CACNA1C ANO1

1.47e-044173228054347
Pubmed

PAX2 protein induces expression of cyclin D1 through activating AP-1 protein and promotes proliferation of colon cancer cells.

FOS PAX2

1.47e-044173223135283
Pubmed

Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.

CACNA1C CACNA1F

1.47e-044173220937870
Pubmed

Homer 2 tunes G protein-coupled receptors stimulus intensity by regulating RGS proteins and PLCbeta GAP activities.

PLCB1 HOMER2

1.47e-044173212860966
Pubmed

Homer2 regulates alcohol and stress cross-sensitization.

PLCB1 HOMER2

1.47e-044173225916683
Pubmed

Joint morphogenetic cells in the adult mammalian synovium.

FOXN1 YAP1

1.47e-044173228508891
Pubmed

Prognostic impact of KMT2A-AFF1-positivity in 926 BCR-ABL1-negative B-lineage acute lymphoblastic leukemia patients treated in GIMEMA clinical trials since 1996.

BCR AFF1

1.47e-044173234048072
Pubmed

AF-6 controls integrin-mediated cell adhesion by regulating Rap1 activation through the specific recruitment of Rap1GTP and SPA-1.

RAP1GAP AFDN

1.47e-044173212590145
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

TCF20 GPATCH8 PBRM1 SNW1 ZFHX4

1.70e-04103173532744500
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

TCF20 SYNE1 RBM10 CASZ1 LPIN1 DST STARD9

1.76e-04233173737704626
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

NET1 TBL1Y SYNE1 SIPA1L3 COPG2 PPHLN1 EXOSC5 ZNF318 CBX4 GPATCH8 TRRAP CASZ1 POTEE PBRM1 DST PLEKHG3 AFDN ZNF281 SMG6

1.79e-0414971731931527615
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

TCF20 BCORL1 MORC4 CASZ1 PBRM1 ZFHX4 ZNF516 LCOR HOMER2

1.83e-04398173935016035
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

WASHC2C VWA8 STXBP5L CAMLG SH3KBP1 ANKS1B TACC2 BCR ADAM22 PTK7 NHSL1 VIPAS39 CASKIN1 PLCB1 NAV1 AFDN

1.94e-0411391731636417873
Pubmed

Genome-wide association study identifies five new schizophrenia loci.

CACNA1C SDCCAG8 RERE

1.99e-0423173321926974
Pubmed

Genome-wide association analysis identifies 13 new risk loci for schizophrenia.

CACNA1C SDCCAG8 ARL6IP4 PBRM1 SMG6

2.21e-04109173523974872
Pubmed

Developmental epigenetic modification regulates stochastic expression of clustered protocadherin genes, generating single neuron diversity.

PCDHA7 PCDHA6 PCDHA1

2.27e-0424173324698270
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

ING1 CHD9 CBX4 GPATCH8 ZNF281

2.31e-04110173526841866
InteractionYWHAH interactions

RAP1GAP TCF20 NET1 ING1 NHSL2 CEP162 POTEF SIPA1L3 PPHLN1 CBX4 BCR ANKRD27 USP31 NHSL1 STOX2 DST SLF2 YAP1 PLEKHG3 STARD9 SVIL NAV1 MTBP AFDN BOD1L1

2.00e-06110216025int:YWHAH
InteractionSP7 interactions

TCF20 ING1 RBM10 ZNF318 GPATCH8 MORC4 PBRM1 ZFHX4 ZNF516 RERE ZNF281 PRRC2B

5.90e-0630416012int:SP7
InteractionPHF21A interactions

CASP8AP2 BCORL1 NUP43 RNF40 ZNF318 MORC4 BCR LLGL2 DST ZFHX4 ZNF516 NAV1

1.97e-0534316012int:PHF21A
InteractionMTMR10 interactions

PTK7 PBRM1 PLEKHG3 SVIL LCOR

1.99e-05421605int:MTMR10
InteractionHNF1B interactions

ING1 MORC4 TRRAP PBRM1 ZFHX4 YAP1 PAX2 ZNF281 PRRC2B

2.16e-051901609int:HNF1B
InteractionNUP43 interactions

CASP8AP2 TCF20 NUP85 NUP43 CHD9 PPHLN1 ZNF318 GPATCH8 ARL6IP4 PBRM1 DST SLF2 BOD1L1 RERE ZNF281 LCOR

3.94e-0562516016int:NUP43
InteractionYWHAZ interactions

RAP1GAP ING1 CEP162 POTEF SIPA1L3 TACC2 CBX4 BCR ANKRD27 ADAM22 SLC3A1 USP31 NHSL1 MYO3A STOX2 ADRA2B DST YAP1 PLEKHG3 STARD9 SVIL NAV1 MTBP AFDN KATNIP

4.33e-05131916025int:YWHAZ
InteractionYWHAB interactions

RAP1GAP ING1 CEP162 POTEF SIPA1L3 CBX4 BCR TRRAP ADAM22 USP31 NHSL1 STOX2 VIPAS39 DST YAP1 PLEKHG3 STARD9 SVIL NAV1 MTBP AFDN

5.45e-05101416021int:YWHAB
InteractionDDN interactions

SH3KBP1 DDN YAP1

5.66e-05101603int:DDN
Cytoband8p23.1

FAM90A17 RP1L1 FAM90A19 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

8.23e-0915417398p23.1
CytobandEnsembl 112 genes in cytogenetic band chr8p23

FAM90A17 RP1L1 FAM90A19 FAM90A7 FAM90A18 FAM90A9 FAM90A8 FAM90A16 FAM90A10

2.99e-072341739chr8p23
GeneFamilyPappalysins|Sushi domain containing

PAPPA2 PAPPA

3.15e-0521022897
GeneFamilyRho GTPase activating proteins|BCH domain containing

ARHGAP40 TAGAP ARHGAP6 ARHGAP25

1.80e-04501024721
GeneFamilyAnkyrin repeat domain containing

TRPV1 POTEF BCORL1 ANKS1B ANKRD27 POTEE CASKIN1

4.43e-042421027403
GeneFamilyWD repeat domain containing

TBL1Y STXBP5L EML4 NUP43 DYNC2I1 LLGL2 CFAP44

7.10e-042621027362
GeneFamilyEF-hand domain containing|Plakins

EVPL DST

8.63e-0481022939
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEF POTEE

2.36e-03131022685
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

CACNA1C APC2 SH3KBP1 ANKS1B PCDHA7 GPRIN3 ZNF318 CBX4 PEX5L CASZ1 CCDC85A LPIN1 STOX2 PRDM8 AJAP1 ZFHX4 CASKIN1 ARNT2 SCN8A RETREG1 NAV1 PAPPA BOD1L1 PRRC2B

1.24e-07110616524M39071
CoexpressionGSE19401_PLN_VS_PEYERS_PATCH_FOLLICULAR_DC_UP

GATD3 ING1 SYNE1 ADAM22 GFRA2 BTD ZNF516 RERE VEGFD

4.46e-061961659M7666
CoexpressionGSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_DN

ING1 SYNE1 ANKS1B TRRAP ANKRD27 LPIN1 ADRA2B PLEKHG3 ZNF281

4.65e-061971659M5475
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HDA1

CACNA1C PCDHA7 TUB ADAM22 CCDC85A LPIN1 PRDM8 AJAP1 ZFHX4 PITX3 SCN8A RETREG1 PLCB1 NAV1 PAPPA

4.66e-0658416515M39068
CoexpressionZHOU_INFLAMMATORY_RESPONSE_FIMA_DN

TIGAR C9orf40 CHD9 CCDC85A FANCE NHSL1 VIPAS39 TRPM3 SLF2 SCN8A

1.17e-0527916510M250
CoexpressionGSE10463_CD40L_AND_VA347_VS_CD40L_IN_DC_UP

EVPL BCR VIPAS39 TXLNB ZFHX4 TTLL6 GYG2 SMG6

3.44e-051951658M3098
CoexpressionGSE3982_MAST_CELL_VS_TH2_UP

MYH7B CAMLG EVPL ANKRD27 LPIN1 PLEKHG3 ZNF516 AFF1

3.84e-051981658M5455
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_ALVEOLAR_FIBROBLAST

ANKS1B AFDN VEGFD

3.89e-05111653M45666
CoexpressionGSE36392_TYPE_2_MYELOID_VS_EOSINOPHIL_IL25_TREATED_LUNG_UP

TOR1AIP2 PMS2 STXBP5L CAMLG SH3KBP1 LPIN1 BTD BOD1L1

3.98e-051991658M5270
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HNBML5

PAPPA2 APC2 ANKS1B CASZ1 CCDC85A LPIN1 AJAP1 ZFHX4 CASKIN1 SCN8A NAV1 PAPPA

4.12e-0546516512M39066
CoexpressionGSE34392_ST2_KO_VS_WT_DAY8_LCMV_EFFECTOR_CD8_TCELL_UP

CBX4 ARL6IP4 LPIN1 NHSL1 ARHGAP6 STARD9 SVIL RERE

4.12e-052001658M8653
CoexpressionLAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2

VWA8 ANKS1B DYNC2I1 CHD9 ARHGAP6 TRPM3 AFDN RERE

8.31e-052211658M39222
CoexpressionHE_LIM_SUN_FETAL_LUNG_C0_ACTC_POS_SMC_CELL

CACNA1C NET1 TAGAP ANO1 PODXL2 TACC2 CASZ1 ZFHX4 EEPD1 SVIL ZNF516 FHDC1 HOMER2

9.64e-0558916513M45662
CoexpressionAtlasFacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_100

RAP1GAP APC2 GPATCH8 USP31 ARHGAP6 PLCB1 FHDC1

8.10e-06971587Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_100
ToppCellpdx|World / Sample and Cell Type and Tumor Cluster (all cells)

TCF20 MYH7B SIPA1L3 GPATCH8 PTK7 LLGL2 SLF2 YAP1 PLCB1 RERE SMG6

1.21e-1018616611de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCellpdx-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

TCF20 MYH7B SIPA1L3 GPATCH8 PTK7 LLGL2 SLF2 YAP1 PLCB1 RERE SMG6

1.21e-10186166110b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 PRSS23 ARHGAP6 AJAP1 SVIL ARNT2 RETREG1 PLCB1

4.42e-0819116699032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 PRSS23 ARHGAP6 AJAP1 SVIL ARNT2 RETREG1 PLCB1

4.42e-0819116695717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellHematolymphoid-Endothelial-NOSTRIN|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C SYNE1 BCR ATP10A STOX2 HEG1 YAP1 ARNT2 RETREG1

6.56e-082001669032df80aa5c40991e1c1e80f9d8da106e6aeaee2
ToppCellHematolymphoid-Endothelial-NOSTRIN---|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C SYNE1 BCR ATP10A STOX2 HEG1 YAP1 ARNT2 RETREG1

6.56e-08200166968fce28690246895fd33354b30960ebcc31aa4cc
ToppCellHematolymphoid-Endothelial-NOSTRIN-|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C SYNE1 BCR ATP10A STOX2 HEG1 YAP1 ARNT2 RETREG1

6.56e-082001669376b19ab5a7cd2c85f726d8ba41337d4525863e5
ToppCellHematolymphoid-Endothelial-NOSTRIN--|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C SYNE1 BCR ATP10A STOX2 HEG1 YAP1 ARNT2 RETREG1

6.56e-0820016697fa54370221ed61bac0e09e6bcf1f3dff202a846
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NET1 EVPL PRSS23 CASZ1 LLGL2 DST PTPRZ1 YAP1 AFDN

6.56e-082001669ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellHematolymphoid-Endothelial-NOSTRIN----L2-6|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C SYNE1 BCR ATP10A STOX2 HEG1 YAP1 ARNT2 RETREG1

6.56e-082001669878bbbe32e3602723aa14ef32877ab2453b8c6e5
ToppCellHematolymphoid-Endothelial|Hematolymphoid / cells hierarchy compared to all cells using T-Statistic

CACNA1C SYNE1 BCR ATP10A STOX2 HEG1 YAP1 ARNT2 RETREG1

6.56e-0820016697136936d05ab344a560cf159684c881063b5430d
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP ANKS1B PCDHA6 PEX5L AJAP1 TRPM3 PTPRZ1 ARNT2

4.30e-071821668d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCellpdx-Tumor_cells-T6|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

RNF19A MYH7B ATP10A LPIN1 ZFHX4 TRPM3 PAX2 RERE

4.30e-0718216687b24a4f712e1ae1525e8f1c8ec4e1fc43489cbee
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP ANKS1B PCDHA6 PEX5L AJAP1 TRPM3 PTPRZ1 ARNT2

4.30e-071821668e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 ANKS1B TACC2 ARHGAP6 AFF1 PAPPA AFDN PAX2

6.19e-0719116683e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

VWA8 EML4 CHD9 GPRIN3 ATP10A DST SVIL RETREG1

6.19e-071911668a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ANKS1B TACC2 ARHGAP6 AFF1 PAPPA AFDN PAX2 TGS1

6.97e-07194166869bff17df4a760ccf081cf52ff04af02c14f448d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 ARHGAP40 LLGL2 DST SVIL ARNT2 PLCB1

7.24e-071951668938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 ARHGAP40 LLGL2 DST SVIL ARNT2 PLCB1

7.24e-071951668d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C STXBP5L SYNE1 ANKS1B COPG2 ADAM22 SCN8A PLCB1

7.53e-071961668676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RAP1GAP SIPA1L3 CASZ1 ARHGAP6 LLGL2 ARNT2 PAX2 RERE

7.53e-071961668eea66711a16134f86e6c533a5a837ff2e0d7ca7f
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C STXBP5L SYNE1 ANKS1B COPG2 ADAM22 SCN8A PLCB1

8.12e-071981668c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C STXBP5L SYNE1 ANKS1B COPG2 ADAM22 SCN8A PLCB1

8.12e-0719816686d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C STXBP5L SYNE1 ANKS1B COPG2 ADAM22 SCN8A PLCB1

8.12e-0719816688ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NET1 EVPL PRSS23 CASZ1 LLGL2 DST PTPRZ1 AFDN

8.76e-07200166897f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1C STXBP5L SYNE1 ANKS1B COPG2 ADAM22 SCN8A PLCB1

8.76e-07200166848d801219bc771d6c7e151dc88ca4c179988de85
ToppCell3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16|GI_small-bowel / Manually curated celltypes from each tissue

SYNE1 PRSS23 BCR CASZ1 CDC45 FCRL3 PLEKHG3

3.84e-061721667701de463f85aaad3a4b36a0d5fbc416406620089
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1C PEX5L ADAM22 USP31 DST TRPM3 AFF1

4.82e-061781667fcbbcc44271515de1969b4732b6441c012693d5f
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVPL PEX5L GFRA2 ZFHX4 PTPRZ1 MTBP PAPPA

5.18e-061801667da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVPL PEX5L GFRA2 ZFHX4 PTPRZ1 MTBP PAPPA

5.18e-0618016675b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EVPL PEX5L GFRA2 ZFHX4 PTPRZ1 MTBP PAPPA

5.18e-06180166750758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM22 CASZ1 ARHGAP6 TRPM3 AFF1 PAPPA PAX2

5.37e-061811667aa233b652921848af2257cc3687a7a09c3acfb67
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP ANKS1B PCDHA6 PEX5L AJAP1 TRPM3 PTPRZ1

5.57e-06182166782ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP ANKS1B PEX5L AJAP1 TRPM3 PTPRZ1 ARNT2

5.99e-0618416679f8cd5ab5af6c35a1be25d70a125b9a3f4dd667a
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APC2 PODXL2 PEX5L GFRA2 ZFHX4 PTPRZ1 DAGLA

6.20e-061851667ca69499ba8c39b7ed6717d05685d6f70066a77bd
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_Arw_fibro_(16)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CACNA1C NHSL2 PRSS23 GFRA2 STOX2 AJAP1 SVIL

6.42e-0618616674d68ee3d32f7ef884faf402ef92b31b0eb4656f1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNE1 STOX2 TRPM3 TMEM132D RETREG1 PLCB1 PAX2

6.42e-061861667f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellhuman_hepatoblastoma-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

TCF20 SIPA1L3 COPG2 CASZ1 RETREG1 PAX2 RERE

6.89e-061881667b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 ARHGAP40 DST SVIL RETREG1 PLCB1

7.13e-061891667aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 DST SVIL ARNT2 PLCB1 HOMER2

7.13e-0618916678c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 ARHGAP40 DST SVIL RETREG1 PLCB1

7.13e-0618916678977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 DST SVIL ARNT2 PLCB1 HOMER2

7.13e-0618916675d902a4660a27548764bf04c6de152b565da835c
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TBL1Y ANO1 MYO3A HEG1 SYTL5 EEPD1 HOMER2

7.38e-06190166756cc761e50fddfb5366391518b4d8e16589b6b42
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TBL1Y ANO1 MYO3A HEG1 SYTL5 EEPD1 HOMER2

7.38e-06190166725d4b591f75c26e404a34c42f1742d580af6598d
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

CACNA1C VWA8 MYH7B TACC2 CASZ1 DST SVIL

7.38e-061901667fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

CACNA1C VWA8 MYH7B TACC2 DST SVIL RETREG1

7.64e-06191166725f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 ARHGAP40 LLGL2 SVIL ARNT2 PLCB1

7.64e-0619116675a67ff17fb4b9eff641176dff07830c9cd73754e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 ARHGAP40 LLGL2 SVIL ARNT2 PLCB1

7.64e-06191166755ab2854a02cdcfc395e49870ccb7290b5e5471d
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ARHGAP40 SYNE1 LLGL2 SVIL PLCB1 AFDN

8.18e-061931667f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 LLGL2 AJAP1 SVIL ARNT2 PLCB1

8.18e-061931667263d185af6ed80e639f864e4966268e0862c61dc
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 LLGL2 AJAP1 SVIL ARNT2 PLCB1

8.18e-06193166780e058c224749b5fe0ba3e944b48317c2371cb63
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 COL7A1 LLGL2 AJAP1 SVIL ARNT2 PLCB1

8.18e-061931667b991fbbb4618401624f0b3045f0e81a606d3a763
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 TACC2 ARHGAP6 LLGL2 TRPM3 AFDN PAX2

8.18e-0619316673866667dd221612589ae50f5c52f73a183a49ce6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ARHGAP40 SYNE1 LLGL2 SVIL PLCB1 AFDN

8.18e-06193166742df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TACC2 ARHGAP6 AFF1 PAPPA AFDN PAX2 TGS1

8.46e-06194166704bfc555743f7d8821439d05ae442d15e9886c59
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ANKS1B ADAM22 ARHGAP6 DST ZFHX4 ARNT2 RERE

8.46e-061941667b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 SYNE1 STOX2 LLGL2 SVIL PLCB1 AFDN

8.46e-061941667e577d9e88390b36b5a09b97fe1026089892275a3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CASZ1 SLC3A1 ARHGAP6 LLGL2 TRPM3 ARNT2 PAX2

8.46e-06194166793c68c31e39fa44c1d05d7d4997f4f086da4e738
ToppCellParenchymal-NucSeq-Stromal-Mesofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRO PEX5L ZFHX4 PTPRZ1 PLCB1 GYG2 PAPPA

8.74e-061951667a52685f76eca269a7d2de8dfc317439483e233fa
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 CASZ1 ARHGAP6 LLGL2 AFDN PAX2 RERE

8.74e-0619516676477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCellParenchymal-NucSeq-Stromal-Mesofibroblastic-Mesothelia|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TRO PEX5L ZFHX4 PTPRZ1 PLCB1 GYG2 PAPPA

8.74e-061951667224deeba2f60def6543a55bb4f5ee6c7fdab3f02
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 TACC2 LLGL2 ZFHX4 PLEKHG3 AFDN PAX2

9.04e-061961667c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SIPA1L3 CASZ1 SLC3A1 ARHGAP6 LLGL2 ARNT2 PAX2

9.04e-0619616676ce74aa3f0ce3ca284b67e5a4660ffd2cc9611e0
ToppCellmild-low-quality_cells|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

SYNE1 GPRIN3 ADAM22 CASZ1 LPIN1 LLGL2 STARD9

9.35e-061971667e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C STXBP5L SYNE1 COPG2 ADAM22 SCN8A PLCB1

9.66e-0619816674ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1C NHSL2 CCDC85A HEG1 STARD9 PLCB1 NAV1

9.66e-0619816678689090bce9ab6e8f122426a404037e572c6713b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1C STXBP5L ANKS1B COPG2 ADAM22 SCN8A PLCB1

9.66e-0619816670ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STXBP5L TRO SYNE1 TACC2 TMEM132D ARNT2 NAV1

9.98e-061991667333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STXBP5L TRO SYNE1 TACC2 TMEM132D ARNT2 NAV1

9.98e-06199166719a97e27a4758e794ce7246d295e112b47931a48
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

STXBP5L TRO SYNE1 TACC2 TMEM132D ARNT2 NAV1

9.98e-061991667e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NET1 ANKS1B ANO1 CASZ1 PTPRZ1 PLCB1 HOMER2

1.03e-052001667030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_only / Treatment groups by lineage, cell group, cell type

PAPPA2 RAP1GAP SYNE1 ANO1 TACC2 DST SVIL

1.03e-052001667593bf6a7c557437db9a9249a5058a46014179ef6
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

SYNE1 ANO1 TACC2 ADAM22 DST ZFHX4 SVIL

1.03e-05200166708bf8c00eee6468215edb3611296bfc8784c4d56
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ANO1 TACC2 CASZ1 STOX2 LLGL2 SVIL HOMER2

1.03e-0520016670eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCellLPS-IL1RA-Lymphocytic_NKT-iNKT/MAIT-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TAGAP TCEANC PEX5L SLC3A1 VIPAS39 ARNT2

1.07e-0513316662ec3490cbf60152c3cece95eb566d749c9666517
ToppCellSevere-B_naive-1|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

WASHC2C TCF20 ZNF318 SLF2 RETREG1 LCOR

2.95e-0515916662881b054bbeb479221ee3c38bbd9b0815b123579
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma|TCGA-Brain / Sample_Type by Project: Shred V9

NET1 TUB LPIN1 DST EEPD1 PLCB1

3.16e-051611666347edb0de10850b7d16c40945751033289289c9b
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CACNA1F TOGARAM1 GPRIN3 VIPAS39 BOD1L1

3.48e-05991665a815a887094204de30b299e8907e81ad9a39c016
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYH7B GPRIN3 PEX5L CCDC85A PRDM8 ARNT2

3.88e-051671666e1b1a952fce27ab9cf16919b290625ff4a75261e
ToppCell343B-Myeloid-Dendritic-cDC_proliferating_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

COL7A1 OOEP LCT CDC45 TRBV7-3 PLCB1

3.88e-0516716663461d14e36f09ddc6ee5549ca4797e16d3f37fcc
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-Glial_immature-Glia_2_(ELN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDHA1 DST TRPM3 PTPRZ1 PAPPA FHDC1

4.01e-051681666af82e07d1eec51fc6530155f37addbce6221885d
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

MYO3A STOX2 TRPM3 TMEM132D ARNT2 PAX2

4.01e-051681666a086c306be430adf0632ba53e98cd8014d2de330
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell_prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CASP8AP2 SYNE1 CDC45 NHSL1 HEG1 NAV1

4.73e-051731666f193c63cc536d891c9d23043765e320252bb6e65
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C NET1 ANO1 MYO3A PLCB1 PAPPA

4.88e-051741666015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CACNA1C CBX4 ADAM22 PLEKHG3 MTBP DAGLA

5.04e-051751666bde785ff0c854646d7ab8571359e9d69a7bf013f
ToppCellPND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CASP8AP2 PODXL2 GFRA2 KEL VEGFD DAGLA

5.20e-051761666d30241fb8119834d6e7b59efec3f92fc7a3d1247
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-Glia_3_(BCAN+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAP1GAP ANKS1B DST PTPRZ1 ARNT2 DAGLA

5.37e-051771666d05497d2c80a66ec6a4e1733fea3a5534877a6a7
ToppCell10x5'v1-week_17-19-Lymphocytic_NK-T_NK-mature_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SYNE1 GPRIN3 PRSS23 PRDM8 HEG1 FCRL3

5.37e-0517716660f2616a81f8fbede77c860b2126e3fa826672da3
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

NET1 SYNE1 BCR TUB ADAM22 DST

5.37e-051771666e8ab340b20cd41554c3841fe980e078e878af35f
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAP1GAP ANKS1B PEX5L TRPM3 PTPRZ1 ARNT2

5.54e-051781666ef490b45901b2e6dedb519540fa3ae4e4db3a9ba
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS23 PEX5L GFRA2 AJAP1 ZFHX4 PTPRZ1

5.54e-0517816663e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs|Myeloid_cells / Location, Cell class and cell subclass

NET1 MORC4 NHSL1 ARNT2 NAV1 HOMER2

5.71e-0517916665f7e6670a0e906a0a5bc75735408361d88e78fa2
ToppCellFF-Differ-KC|World / shred by cell class for mouse tongue

FOXN1 ARHGAP40 PRSS23 NHSL1 ZFHX4 HOMER2

5.71e-0517916661526a130565a97c291a25a7a988089bffc1515c1
ToppCellCOVID-19-kidney-PCT-S2|COVID-19 / Disease (COVID-19 only), tissue and cell type

SLC3A1 STOX2 TRPM3 RETREG1 PAPPA PAX2

5.89e-051801666358923e4228035a3e90e2957392089219e90dcd7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS23 PEX5L GFRA2 AJAP1 PTPRZ1 PAPPA

5.89e-051801666d9c9399df3e2d9f23dbbfffb6cbe8404bf01e2b7
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS23 PEX5L GFRA2 AJAP1 PTPRZ1 PAPPA

5.89e-051801666dad458398683ff80a6e207bdc08e257d1bb757d6
ToppCelldroplet-Marrow-nan-3m-Hematologic-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CASP8AP2 EML4 FOS SH3KBP1 CHD9 BOD1L1

6.26e-051821666e78ba2c5cae480c16a596ce7c3bf2d480becacf4
ToppCelldroplet-Limb_Muscle-nan-21m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ANKS1B PEX5L AJAP1 TRPM3 PTPRZ1 FHDC1

6.26e-051821666a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS23 PEX5L GFRA2 AJAP1 PTPRZ1 PAPPA

6.26e-051821666812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell3'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RAP1GAP ANKS1B DST TRPM3 PTPRZ1 ARNT2

6.26e-051821666ecb5624c9074cc6449fad961df54c926c2681d54
ComputationalGenes in the cancer module 459.

CEP162 FOS SIPA1L3 CHD9 ZNF318 BCR AMIGO1 PRDM8 PTPRZ1 KATNIP RERE HOMER2

2.64e-044319112MODULE_459
ComputationalGenes in the cancer module 378.

CEP162 FOS SIPA1L3 CHD9 ZNF318 BCR AMIGO1 PRDM8 PTPRZ1 KATNIP RERE HOMER2

2.87e-044359112MODULE_378
ComputationalGenes in the cancer module 317.

CEP162 FOS SIPA1L3 CHD9 ZNF318 BCR AMIGO1 PRDM8 PTPRZ1 KATNIP RERE HOMER2

3.19e-044409112MODULE_317
ComputationalGenes in the cancer module 255.

CEP162 FOS SIPA1L3 CHD9 ZNF318 BCR AMIGO1 PRDM8 PTPRZ1 KATNIP RERE HOMER2

3.91e-044509112MODULE_255
ComputationalBlood cells and cancer expression cancer.

CEP162 FOS SIPA1L3 CHD9 ZNF318 BCR AMIGO1 PRDM8 PTPRZ1 KATNIP RERE HOMER2

5.56e-044689112MODULE_179
ComputationalBlood cells and cancer expression clusters.

CEP162 FOS SIPA1L3 CHD9 ZNF318 AMIGO1 PRDM8 PTPRZ1 KATNIP RERE HOMER2

6.21e-044079111MODULE_532
DrugLeucomisine [17946-87-1]; Up 200; 16.2uM; PC3; HT_HG-U133A

COL7A1 TRPV1 RAP1GAP SYNE1 BCORL1 DDN RNF40 ARHGAP6 RERE HOMER2 PRRC2B

2.08e-07199163117125_UP
Diseasepulse pressure measurement

PAPPA2 ING1 SDCCAG8 ANO1 PCDHA7 PCDHA6 PCDHA1 ZNF318 GPATCH8 LARP4 CASZ1 PRDM8 ADRA2B PBRM1 ZFHX4 TRPM3 TTLL6 YAP1 EEPD1 ZNF516 NAV1 PAX2 SMG6

1.38e-06139215723EFO_0005763
Diseasevital capacity

PAPPA2 TCF20 MYH7B CEP162 SYNE1 CAMLG PCDHA7 GPRIN3 PCDHA6 PCDHA1 LCT CASZ1 FANCE LLGL2 DST PLCB1 AFF1 PAX2 DAGLA HOMER2 SMG6

2.70e-06123615721EFO_0004312
Diseasebipolar I disorder

CACNA1C SYNE1 ANKS1B PCDHA1 TTBK2 PBRM1 STARD9

1.10e-051411577EFO_0009963
DiseaseMalignant neoplasm of breast

COL7A1 RAP1GAP NET1 FOS SYNE1 APC2 BCORL1 PPHLN1 TACC2 ZNF318 LLGL2 PBRM1 FCRL3 YAP1 PLCB1 AFF1 BOD1L1 ZNF281

1.77e-05107415718C0006142
Diseaseneuroticism measurement, cognitive function measurement

CACNA1C SDCCAG8 ANKS1B DDN PCDHA7 PCDHA6 PCDHA1 CCDC85A GFRA2 AMIGO1 NAV1 RERE

5.41e-0556615712EFO_0007660, EFO_0008354
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1C CACNA1F

1.68e-0441572DOID:0060173 (implicated_via_orthology)
DiseaseAnophthalmia-microphthalmia syndrome

GATD3 PITX3 PAX2

1.83e-04211573cv:C5680330
DiseaseCerebellar Ataxia

SYNE1 SCN8A

2.78e-0451572C0007758
Diseaseaortic root size

CACNA1C ANO1 SMG6

3.51e-04261573EFO_0005037
Diseaseage at menarche

PAPPA2 ARHGAP40 DDN CCDC85A PTK7 DST ZFHX4 TRPM3 PLCB1 PAX2 RERE

3.56e-0459415711EFO_0004703
Diseaserenal overload-type gout

SPATA31C2 SPATA31C1

4.16e-0461572EFO_0021525
Diseaseneutrophil count

PAPPA2 WASHC2C TAGAP BCORL1 CHD9 PCDHA7 PCDHA6 PCDHA1 LCT CASZ1 RP1L1 ZNF516 PLCB1 AFF1 ARHGAP25 RERE SMG6 TGS1

4.20e-04138215718EFO_0004833
Disease1,5 anhydroglucitol measurement

PCDHA7 PCDHA6 PCDHA1

4.88e-04291573EFO_0008009
Diseasemigraine disorder

FAM47A CASZ1 GFRA2 TRPM3 YAP1 SVIL PAPPA SMG6

6.80e-043571578MONDO_0005277
Diseaseblood urea nitrogen measurement

CHD9 GPRIN3 PPHLN1 ZNF318 PRSS23 CASZ1 PRDM8 SLF2 PLCB1

7.38e-044521579EFO_0004741
Diseaseeosinophil cationic protein measurement

SPATA31C2 SPATA31C1

7.71e-0481572EFO_0010913
Diseasecoloboma (implicated_via_orthology)

YAP1 PAX2

7.71e-0481572DOID:12270 (implicated_via_orthology)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1C CACNA1F EML4

9.28e-04361573DOID:11723 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

CACNA1C TIGAR SDCCAG8 ANO1 PPHLN1 CASZ1 PTK7 TRPM3 SVIL NAV1 AFF1

9.59e-0467015711EFO_0006335, EFO_0006336
Diseasepost-traumatic stress disorder symptom measurement

SYNE1 PCDHA7 PCDHA6 PCDHA1

9.77e-04821574EFO_0008535
Diseaselongitudinal alcohol consumption measurement

SPATA31C2 SPATA31C1

9.88e-0491572EFO_0007645
Diseasecholesteryl ester 20:4 measurement

CASZ1 NHSL1 DAGLA

1.67e-03441573EFO_0010348
Diseasemicrophthalmia (implicated_via_orthology)

ARHGAP6 TRPM3

1.79e-03121572DOID:10629 (implicated_via_orthology)
DiseaseDisease Exacerbation

COL7A1 RAP1GAP ING1 EXOSC5 YAP1

1.94e-031651575C0235874
Diseasecryptic phenotype measurement

CASZ1 PRDM8 PLCB1

2.02e-03471573EFO_0021487
Diseasesystolic blood pressure, alcohol consumption measurement

CASZ1 PRDM8 RP1L1

2.02e-03471573EFO_0006335, EFO_0007878
Diseaseattention deficit hyperactivity disorder, unipolar depression, bipolar disorder, autism spectrum disorder, schizophrenia

CACNA1C SYNE1 ANKS1B RERE

2.11e-031011574EFO_0003756, EFO_0003761, EFO_0003888, MONDO_0004985, MONDO_0005090
Diseaseegg allergy measurement, parental genotype effect measurement

SPATA31C2 SPATA31C1

2.11e-03131572EFO_0005939, EFO_0007018
Diseaseglycodeoxycholate measurement

COL7A1 SVIL

2.45e-03141572EFO_0010493
Diseasemean arterial pressure, alcohol consumption measurement

CASZ1 PRDM8 RP1L1

2.70e-03521573EFO_0006340, EFO_0007878
DiseaseIntellectual Disability

TCF20 SYNE1 SDCCAG8 APC2 TRRAP ADRA2B TRPM3 SCN8A

2.80e-034471578C3714756
Diseaseresponse to olanzapine

CACNA1C ANKS1B

2.82e-03151572GO_0097333
DiseaseAntihypertensive use measurement

CACNA1C ZNF318 CASZ1 PRDM8 PLCB1 SMG6

3.03e-032651576EFO_0009927
Diseasecardiovascular disease

LINC00322 ZNF318 CASZ1 PRDM8 PLCB1 NAV1 PAX2 RERE

3.20e-034571578EFO_0000319
Diseaseamygdala volume change measurement

SPATA31C2 SPATA31C1

3.21e-03161572EFO_0021490
DiseaseBeta blocking agent use measurement

CASZ1 PRDM8 PLCB1 SMG6

3.27e-031141574EFO_0009929
Diseasefacial morphology measurement

SIPA1L3 DYNC2I1 BCR CASZ1 NHSL1 ARHGAP6 TMEM132D SMG6

3.60e-034661578EFO_0007841
Diseasebipolar disorder

CACNA1C TCF20 SYNE1 ANKS1B DDN PEX5L PBRM1 STARD9 HOMER2

3.87e-035771579MONDO_0004985
DiseaseTourette syndrome, schizophrenia

TCF20 RERE

4.07e-03181572EFO_0004895, MONDO_0005090
Diseasecleft lip

SYNE1 ZNF318 CCDC85A DST TMEM132D SVIL

4.25e-032841576EFO_0003959
Diseaseemphysema pattern measurement

VWA8 SVIL

4.53e-03191572EFO_0005850
Diseasecarcinoma (implicated_via_orthology)

ING1 LLGL2 YAP1

4.86e-03641573DOID:305 (implicated_via_orthology)
Diseasesystolic blood pressure, alcohol drinking

ZNF318 CASZ1 PRDM8 RP1L1

4.94e-031281574EFO_0004329, EFO_0006335
Diseasemyelodysplastic syndrome (is_marker_for)

RAP1GAP PLCB1

5.02e-03201572DOID:0050908 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
RSKSQDADSPGSSGA

AFDN

1771

P55196
HRPGSGAEEESQTKS

CAMLG

51

P49069
HPRSSQGTESGKDSE

SMG6

861

Q86US8
GKLRAQASGSAHSTP

RNF40

516

O75150
RGVEKPSSHQGDSLS

AMIGO1

401

Q86WK6
SSSPHLSSKGRGSRD

BCR

461

P11274
KRADAGSHTEGSPSQ

CASZ1

46

Q86V15
QSPGKRADSHEEGSL

BCORL1

1191

Q5H9F3
KSTFNGNRPSSSDRH

AJAP1

381

Q9UKB5
PHNDDAKTGITLSGN

ADAM22

716

Q9P0K1
ASAREVNGHSKSTGE

ADRA2B

241

P18089
RKDKQSGDGSRHSGS

FLG

1221

P20930
QSHKESARGQSGESS

FLG

1421

P20930
SRHSQVGQGESAGSK

FLG

1571

P20930
SHKESARGQSGESSG

FLG

2071

P20930
NSGSDSHPQAKATGS

DDN

326

O94850
SHPQAKATGSAGTEI

DDN

331

O94850
TQDASSEAKSEGNHP

CASP8AP2

1741

Q9UKL3
NPDKEEQLTTSGSGH

CFAP44

281

Q96MT7
DAGSQESSPSNGHGK

EEPD1

366

Q7L9B9
PNGKGSTESSEHLRV

FAM90A10

131

A6NDY2
AQGRLPKDSGTEHSS

ATP10A

1326

O60312
PKDSGTEHSSGRTVK

ATP10A

1331

O60312
DGEGPSKFSRENHSE

ARNT2

56

Q9HBZ2
PEKSSLFHQGGRSST

NUP43

296

Q8NFH3
QSADGHKETGAPSKE

RBM10

621

P98175
PNGKGSTESSEHLRV

FAM90A7

131

A6NKC0
NSDGSHSKGDGIPDR

IGLV4-69

71

A0A075B6H9
HSKGDGIPDRFSGSS

IGLV4-69

76

A0A075B6H9
ESGQAPKASSRASVG

PCDHA6

671

Q9UN73
NGSTEEEKPSGHKLS

KIAA1107

236

Q9UPP5
RGDHRSPASAQKFSS

NET1

126

Q7Z628
LPAQSGSHAAEKGNS

ANKRD27

986

Q96NW4
QARKGGHSSTLPESF

ANKS1B

1191

Q7Z6G8
ESGQAPKASSRASLG

PCDHA7

671

Q9UN72
GATKSRHEDSGDQAS

PODXL2

216

Q9NZ53
DPSHGKRGSADSLVE

CACNA1F

1886

O60840
SSFAHKPQASGGQEE

FHDC1

596

Q9C0D6
RESGKSNVGTSGDHD

POTEF

36

A5A3E0
AQGPRDSAAEKSTGS

CASKIN1

1396

Q8WXD9
TGPSHSKGSLGEERN

PBRM1

311

Q86U86
PQSGKSAVSRHSSFG

KIAA0100

551

Q14667
DSAETKNHRPGNGAG

LLGL2

936

Q6P1M3
AAHRKGSSSNEPSSD

FOS

356

P01100
ISNTSGEDEKTHPGF

DST

2316

Q03001
GSRKDAGSSSHGDDQ

KATNIP

856

O60303
GTDDEKASHAGPANT

HOMER2

146

Q9NSB8
DHTKGQPSEGESRNV

GATD3B

91

A0A0B4J2D5
GASSKRDGTSSQHAE

DYNC2I1

301

Q8WVS4
AKSSSQGDHGSAAER

NHSL1

1146

Q5SYE7
HGSETEDTGRSLPSK

GPATCH8

651

Q9UKJ3
HFGPSGKLASADIDS

MYH7B

296

A7E2Y1
QDGTREGFGHSTSLK

LCOR

136

Q96JN0
SADVLGSENPSKHDS

NUP85

181

Q9BW27
SSEHRSQPELSGGKS

PEX5L

211

Q8IYB4
RTHDAKQGSESPAQA

EVPL

896

Q92817
SDEERAAAKPSNAGH

LPIN1

601

Q14693
THTPGSNVKDNATGD

LCT

936

P09848
LDTGSPESSGKHSER

LMNTD2

246

Q8IXW0
SDTPSGARSVKQDHP

ANO1

86

Q5XXA6
HTDAKIRAENGTGSS

EXOSC5

6

Q9NQT4
TSGKSHAASDAPENL

HEG1

146

Q9ULI3
PNGKGSTESSDHLRV

FAM90A17

131

P0DV74
SSDGSEHSLEGQKFP

PTPRZ1

136

P23471
KDGSSPKVEFSNAHG

PAPPA

301

Q13219
PNGKGSTESSDHLRV

FAM90A16

131

P0DV73
PNGKGSTESSDHLRV

FAM90A19

131

P0DV76
PNGDSQSGVDSLRKH

PAX2

236

Q02962
EHEGKVDSPKRTSSG

PPP4R3C

756

Q6ZMV5
ESGQAPKASSRASVG

PCDHA1

671

Q9Y5I3
VGHLSSSKSRESSPG

ARHGAP6

706

O43182
RESGKSNVGTSGDHD

POTEE

36

Q6S8J3
GAAESQRGKQTPAHS

OOEP

6

A6NGQ2
PNGKGSTESSDHLRV

FAM90A8

131

A6NJQ4
KSVQAGEARASPGHT

GYG2

296

O15488
HTGRSKPDTEGNAVS

PAPPA2

91

Q9BXP8
TLNHKEEGSGNTAPD

BOD1L1

161

Q8NFC6
HGSGPSKDSFGELSR

APC2

111

O95996
TGSNSFSPHRGIKQE

CHD9

306

Q3L8U1
SPEKDGSGTDHFIQA

CDC45

386

O75419
TQQHGEEPGKAVSSS

BRME1

56

Q0VDD7
AGSSQGDTESPSHEK

CACNA1C

1781

Q13936
SGTGADPVVSAKSNH

GFRA2

146

O00451
SSPFSGHSDENKATG

LINC00322

166

Q6ZN03
KHRSPGNTTTGERAT

CENPJ

201

Q9HC77
SGEVAEGEARSPSHK

CBX4

281

O00257
GAENATGETDPSHSK

BTD

346

P43251
VHSKTPEGNNGRSGD

CEP170P1

81

Q96L14
SQGRKASTAPGAEAS

ARL6IP4

41

Q66PJ3
HSSKGNANSFPGTLD

CEP162

1141

Q5TB80
ESGSGSNPFQHLEKS

COPG2

11

Q9UBF2
SGSPEHFQKHRSGSS

CCDC85A

311

Q96PX6
KKTHPDDSAGEASSR

FCRL3

696

Q96P31
KPQFRSSGGSEHSTE

LARP4

376

Q71RC2
ADKIRTSTPTGHGAS

DAGLA

1016

Q9Y4D2
DHTKGQPSEGESRNV

GATD3

91

P0DPI2
RGSSLHAEPSKTGVS

FAM47A

371

Q5JRC9
SAHGPEKSQLVSGEA

COL7A1

721

Q02388
PAGSRTGRKSHSLDS

CCDC177

221

Q9NQR7
GSGANRKPSHTSAVS

EML4

86

Q9HC35
HKSLESLADGGSASP

FANCE

236

Q9HB96
SKRRDSGDNSAPSGQ

C9orf40

71

Q8IXQ3
GSISKADHSGSLDPT

GPRIN3

516

Q6ZVF9
ADHSGSLDPTNKGDA

GPRIN3

521

Q6ZVF9
VPKHSAGSGAEESNS

C1orf174

141

Q8IYL3
QEHSDSEKASASLPG

PITX3

36

O75364
GRKDSPHSRSGSSVS

PPHLN1

136

Q8NEY8
GEGKFPSAASREAEH

MTBP

11

Q96DY7
SKVPDLHATSSASGG

NAV1

821

Q8NEY1
SDTSPVAGKKASHDG

SYTL5

166

Q8TDW5
PSDKVGRADAHLGSS

TOR1AIP2

121

Q8NFQ8
HSSKVNSDSGIPGLA

TIGAR

176

Q9NQ88
EVGKRTPDGASRSSH

SPATA31C2

131

B4DYI2
SNDHGSLKAPTAGQE

SPATA31C2

751

B4DYI2
HSAFDRVPSKAAGST

SVIL

346

O95425
EGGKAPASSLHTQEA

SVIL

1151

O95425
AGSGKSQDFTRDHVP

TAGAP

526

Q8N103
QHSAAETSGDAGEKP

SYNE1

6261

Q8NF91
DANPNTSDSRHTGAG

TMEM132D

801

Q14C87
GGRTSSHSPIKNTAE

NHSL2

1136

Q5HYW2
DSGHRPSKETQSAAG

RETREG1

381

Q9H6L5
SSEAPAKNGAGSLRS

PLEKHG3

41

A1L390
GSEKGLARHGSATDS

PLEKHG3

646

A1L390
SGVGETSKRPFSHDN

SDCCAG8

196

Q86SQ7
SSNHDHDDGASGTPK

ING1

306

Q9UK53
RPSSGNSGDADKVAT

OR5L1

261

Q8NGL2
EAAASSPGRFLKGSH

FOXN1

106

O15353
DGAQHRDSGSSGKSR

PRSS23

111

O95084
GGSSAKPSTDFHNLA

PRDM8

251

Q9NQV8
PNGKGSTESSDHLRV

FAM90A9

131

A6NNJ1
PEGENSHDKSSSERS

MORC4

606

Q8TE76
HTRGDSPKIDLAGSS

SH3KBP1

431

Q96B97
GLESVSSSGTPHKRD

RAP1GAP

591

P47736
AGSSGNKHPSRQDAA

SIPA1L3

1236

O60292
DPGSSTDNLKHSTRG

SLC3A1

36

Q07837
AKASSSAHEGRLSDP

RERE

1206

Q9P2R6
STAHAAAGKRTESPG

SLF2

31

Q8IX21
TTQTRGAKGLADPSH

STARD9

971

Q9P2P6
SSNDHGSLKAPTAGQ

SPATA31C1

756

P0DKV0
LKHKSQTDSPDGSSG

OSER1

106

Q9NX31
VEPEGSKRTDAQGHS

SLC28A2

31

O43868
GEASAGKASRSLAQH

STXBP5L

1101

Q9Y2K9
SSEHKGSSGDTANPF

AFF1

926

P51825
PKSGQADGTSEESLH

SWI5

146

Q1ZZU3
GSEVHTTSADAPKQG

ZNF516

1131

Q92618
TTSADAPKQGRDHSN

ZNF516

1136

Q92618
KDSATAAHPSEIARG

ZFHX4

566

Q86UP3
TPAKAGSSTAGVQHR

TTC24

436

A2A3L6
FTEHLSPGSKGQEDS

ARHGAP40

551

Q5TG30
RGNKEENSGPSHDPS

TCEANC

96

Q8N8B7
SPDAHSGGRDSSIKS

RBMXL3

956

Q8N7X1
KFRHNSGSSSVDDGS

RNF19A

626

Q9NV58
NDHVLGDTRSPDAKS

RP1L1

2316

Q8IWN7
TAKAAQGSQSPTGHE

TRO

146

Q12816
DGKNDSLPSESTSHR

TRPV1

601

Q8NER1
TRVSKGDPSDGSHLD

STOX2

376

Q9P2F5
SHPSSDSEENEAKGR

TRPM3

1616

Q9HCF6
SPSSEAKAGEGHRRT

ARHGAP25

471

P42331
ADHTGAGVSQTPSNK

TRBV7-3

16

A0A075B6L6
TNEAVGHKTTGSPSD

TTBK2

566

Q6IQ55
PKSHSRQASTDAGTA

YAP1

101

P46937
IVKGATSAEPGSSNH

ZNF281

371

Q9Y2X9
ANSSTTTLEDKGPGH

PRRC2B

996

Q5JSZ5
ENGGTHREKKESTPS

SCN8A

1926

Q9UQD0
DTSPFAKSLGHSRGE

WASHC2C

1091

Q9Y4E1
SHPGFKDQGADSSQI

TACC2

861

O95359
EEAKQHGGSKRPSDS

SNW1

506

Q13573
GNSGSTHEGREQLKS

VIPAS39

76

Q9H9C1
HGLAEATQSSKPGSV

TCF20

1221

Q9UGU0
REGGHDVPSNKDVTS

TBL1Y

226

Q9BQ87
PGECHSRSDSSGEKR

TTLL6

761

Q8N841
GKISEDSNHGSAPLS

PLCB1

1171

Q9NQ66
ASSPGDRGSQEHVDS

PMS2

521

P54278
SSSLPSHNGLEKEDG

TXLNB

21

Q8N3L3
KADSSSRGSGRHSSP

USP31

1076

Q70CQ4
QKSSDPTGRNHGENS

TOGARAM1

871

Q9Y4F4
NTSKDRPHASGTDGD

TGS1

396

Q96RS0
GSSNEHGPVKRSSQS

VEGFD

21

O43915
ADHTGAGVSQSPSNK

TRBV7-2

16

A0A1B0GXF2
NRDSGEDVSSPKHGK

VWA8

1541

A3KMH1
SLGSGPAATNKRHST

PTK7

771

Q13308
THKGGQRSDGNESIS

TRRAP

1481

Q9Y4A5
HKGTSGPAALAEDKS

TUB

131

P50607
ARSSVSSHRPKDDGG

ZNF318

6

Q5VUA4
TPFTSKGHRTGSNSD

TEX13B

291

Q9BXU2
PNGKGSTESSDHLRV

FAM90A18

131

P0DV75
LGGDPSKVQEHSSLS

KEL

261

P23276
SLLKHDSSPSGNGDE

MYO3A

696

Q8NEV4