Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	triplex DNA binding	DDX12P DDX11L8 DDX11	2.66e-07	4	82	3	GO:0045142
GeneOntologyMolecularFunction	5'-3' DNA helicase activity	DDX12P DDX11L8 DDX11	1.08e-05	11	82	3	GO:0043139
GeneOntologyMolecularFunction	G-quadruplex DNA binding	DDX12P DDX11L8 DDX11	2.35e-05	14	82	3	GO:0051880
GeneOntologyMolecularFunction	DNA replication origin binding	DDX12P DDX11L8 DDX11	5.21e-05	18	82	3	GO:0003688
GeneOntologyMolecularFunction	4 iron, 4 sulfur cluster binding	DDX12P DDX11L8 DDX11	9.50e-04	47	82	3	GO:0051539
GeneOntologyMolecularFunction	calcium ion binding	CACNA1E NAALADL1 PCDHGB6 OTOF PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	9.70e-04	749	82	10	GO:0005509
GeneOntologyMolecularFunction	ADP binding	MYO18A PRKAG2 NOD2	1.01e-03	48	82	3	GO:0043531
GeneOntologyMolecularFunction	single-stranded RNA binding	CPEB2 DDX12P DDX11L8 DDX11	1.13e-03	111	82	4	GO:0003727
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	8.88e-06	187	81	7	GO:0007156
GeneOntologyBiologicalProcess	establishment of sister chromatid cohesion	DDX12P DDX11L8 DDX11	9.41e-06	11	81	3	GO:0034085
GeneOntologyCellularComponent	microtubule organizing center	HAUS8 TTBK2 CCDC13 DDX12P HK2 MCPH1 CENPF PDE4DIP MYO18A OBSL1 RASSF10 CEP152 TACC2 DDX11L8 DDX11	2.13e-06	919	81	15	GO:0005815
GeneOntologyCellularComponent	Ctf18 RFC-like complex	DDX12P DDX11L8 DDX11	6.60e-06	10	81	3	GO:0031390
GeneOntologyCellularComponent	centrosome	HAUS8 CCDC13 DDX12P HK2 MCPH1 CENPF PDE4DIP OBSL1 RASSF10 CEP152 TACC2 DDX11L8 DDX11	7.72e-06	770	81	13	GO:0005813
GeneOntologyCellularComponent	spindle pole	HAUS8 DDX12P CENPF RASSF10 DDX11L8 DDX11	1.46e-04	205	81	6	GO:0000922
HumanPheno	Lumbar hyperlordosis	KY COL6A3 VAC14 PIEZO2 OBSL1 POMK	2.30e-05	99	31	6	HP:0002938
MousePheno	increased allantois apoptosis	DDX12P DDX11L8 DDX11	5.79e-06	8	67	3	MP:0003891
MousePheno	absent paraxial mesoderm	DDX12P DDX11L8 DDX11	8.66e-06	9	67	3	MP:0012184
MousePheno	decreased paraxial mesoderm size	DDX12P DDX11L8 DDX11	2.24e-05	12	67	3	MP:0012183
MousePheno	abnormal circulating interleukin-2 level	IL10RA FOXN1 NOD2	3.69e-05	14	67	3	MP:0008598
MousePheno	small allantois	DDX12P DDX11L8 DDX11	5.64e-05	16	67	3	MP:0004559
MousePheno	increased acetylcholine level	CPEB2 CHAT	6.77e-05	3	67	2	MP:0030676
MousePheno	placental labyrinth hypoplasia	DDX12P DDX11L8 DDX11	1.13e-04	20	67	3	MP:0001715
MousePheno	abnormal acetylcholine level	CPEB2 CHAT	1.35e-04	4	67	2	MP:0030675
MousePheno	abnormal amniotic cavity morphology	DDX12P DDX11L8 DDX11	2.24e-04	25	67	3	MP:0011199
Domain	Cadherin_CS	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	3.26e-07	109	77	7	IPR020894
Domain	CADHERIN_1	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	4.17e-07	113	77	7	PS00232
Domain	Cadherin	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	4.17e-07	113	77	7	PF00028
Domain	CADHERIN_2	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	4.43e-07	114	77	7	PS50268
Domain	-	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	4.43e-07	114	77	7	2.60.40.60
Domain	CA	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	4.70e-07	115	77	7	SM00112
Domain	Cadherin-like	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	4.99e-07	116	77	7	IPR015919
Domain	Cadherin	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1 CDH11 CDH15	5.60e-07	118	77	7	IPR002126
Domain	Cadherin_2	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1	7.11e-06	65	77	5	PF08266
Domain	Cadherin_N	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1	7.11e-06	65	77	5	IPR013164
Domain	Cadherin_tail	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	1.59e-05	37	77	4	PF15974
Domain	Cadherin_CBD	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	1.59e-05	37	77	4	IPR031904
Domain	Calcineurin-like_Pesterase	MPPED2 MPPED1	1.68e-05	2	77	2	IPR024201
Domain	Cadherin_C	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	2.65e-05	42	77	4	IPR032455
Domain	Cadherin_C_2	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	2.65e-05	42	77	4	PF16492
Domain	FN3_dom	IL10RA COL6A3 COL7A1 OBSL1 LRIT1	1.72e-03	209	77	5	IPR003961
Domain	-	COL6A3 COL7A1	2.46e-03	18	77	2	4.10.410.10
Domain	Prtase_inh_Kunz-CS	COL6A3 COL7A1	2.46e-03	18	77	2	IPR020901
Domain	BPTI_KUNITZ_2	COL6A3 COL7A1	2.74e-03	19	77	2	PS50279
Domain	Kunitz_BPTI	COL6A3 COL7A1	2.74e-03	19	77	2	PF00014
Domain	BPTI_KUNITZ_1	COL6A3 COL7A1	2.74e-03	19	77	2	PS00280
Domain	Kunitz_BPTI	COL6A3 COL7A1	4.01e-03	23	77	2	IPR002223
Domain	Cadherin_cytoplasmic-dom	CDH11 CDH15	4.73e-03	25	77	2	IPR000233
Domain	Cadherin_C	CDH11 CDH15	4.73e-03	25	77	2	PF01049
Domain	Calcineurin-like_PHP_ApaH	MPPED2 MPPED1	5.92e-03	28	77	2	IPR004843
Domain	Metallophos	MPPED2 MPPED1	5.92e-03	28	77	2	PF00149
Domain	Catenin_binding_dom	CDH11 CDH15	6.34e-03	29	77	2	IPR027397
Domain	-	CDH11 CDH15	6.34e-03	29	77	2	4.10.900.10
Domain	Metallo-depent_PP-like	MPPED2 MPPED1	6.77e-03	30	77	2	IPR029052
Domain	-	MPPED2 MPPED1	6.77e-03	30	77	2	3.60.21.10
Domain	FN3	COL6A3 COL7A1 OBSL1 LRIT1	7.19e-03	185	77	4	SM00060
Domain	Sema	SEMA3B PLXNA4	7.22e-03	31	77	2	SM00630
Domain	Semap_dom	SEMA3B PLXNA4	7.22e-03	31	77	2	IPR001627
Domain	Sema	SEMA3B PLXNA4	7.22e-03	31	77	2	PF01403
Domain	SEMA	SEMA3B PLXNA4	7.22e-03	31	77	2	PS51004
Domain	PSI	SEMA3B PLXNA4	7.68e-03	32	77	2	PF01437
Domain	Plexin_repeat	SEMA3B PLXNA4	7.68e-03	32	77	2	IPR002165
Pubmed	Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.	DDX12P DDX11L8 DDX11	1.26e-08	3	82	3	17611414
Pubmed	Mammalian ChlR1 has a role in heterochromatin organization.	DDX12P DDX11L8 DDX11	1.26e-08	3	82	3	21854770
Pubmed	The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis.	DDX12P DDX11L8 DDX11	7.01e-07	8	82	3	22678773
Pubmed	Cadherin superfamily genes: functions, genomic organization, and neurologic diversity.	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1	9.13e-07	74	82	5	10817752
Pubmed	Phylogenetic analysis of the cadherin superfamily allows identification of six major subfamilies besides several solitary members.	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1	1.11e-06	77	82	5	10835267
Pubmed	Analysis of mouse embryonic patterning and morphogenesis by forward genetics.	TTBK2 DDX12P DDX11L8 DDX11	1.11e-06	33	82	4	15755804
Pubmed	Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes.	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1	1.35e-06	80	82	5	10716726
Pubmed	Congenital hydrocephalus in hy3 mice is caused by a frameshift mutation in Hydin, a large novel gene.	VAC14 HYDIN	5.49e-06	2	82	2	12719380
Pubmed	The 239AB gene on chromosome 22: a novel member of an ancient gene family.	MPPED2 MPPED1	5.49e-06	2	82	2	9266672
Pubmed	Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion.	DDX12P DDX11	5.49e-06	2	82	2	32855419
Pubmed	cDNA sequence, genomic organization, and evolutionary conservation of a novel gene from the WAGR region.	MPPED2 MPPED1	5.49e-06	2	82	2	8666403
Pubmed	Localization of chi1-related helicase genes to human chromosome regions 12p11 and 12p13: similarity between parts of these genes and conserved human telomeric-associated DNA.	DDX12P DDX11	5.49e-06	2	82	2	8833153
Pubmed	Characterization of putative human homologues of the yeast chromosome transmission fidelity gene, CHL1.	DDX12P DDX11	5.49e-06	2	82	2	9013641
Pubmed	Comparative DNA sequence analysis of mouse and human protocadherin gene clusters.	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	2.08e-05	68	82	4	11230163
Pubmed	Tfap2a and 2b act downstream of Ptf1a to promote amacrine cell differentiation during retinogenesis.	CHAT POU4F2 TFAP2A	2.16e-05	23	82	3	25966682
Pubmed	A striking organization of a large family of human neural cadherin-like cell adhesion genes.	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	2.61e-05	72	82	4	10380929
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	CACNA1E BBX PCDHGB6 CENPF PCDHGA10 PCDHGA5 PCDHGA2 SCG3 MYO18A PLXNA4 SPDEF BAHCC1 DDX11	3.15e-05	1442	82	13	35575683
Pubmed	Genetic mapping of the mouse neuromuscular mutation kyphoscoliosis.	KY COL7A1	3.28e-05	4	82	2	7774920
Pubmed	Cadherins M, 11, and 6 expression patterns suggest complementary roles in mouse neuromuscular axis development.	CDH11 CDH15	3.28e-05	4	82	2	9675053
Pubmed	A tripartite complex containing MRCK modulates lamellar actomyosin retrograde flow.	LURAP1 MYO18A	3.28e-05	4	82	2	18854160
Pubmed	The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis.	AP1M2 TFAP2A	3.28e-05	4	82	2	18843039
Pubmed	Complementary expression and regulation of cadherins 6 and 11 during specific steps of motoneuron differentiation.	CHAT CDH11	3.28e-05	4	82	2	12139922
Pubmed	Temporal requirements for ISL1 in sympathetic neuron proliferation, differentiation, and diversification.	CENPF SCG3 PLXNA4 CHAT	3.41e-05	77	82	4	29445148
Pubmed	Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.	CHAT POU4F2 TFAP2A	4.90e-05	30	82	3	30127719
Pubmed	Polycomb repression complex 2 is required for the maintenance of retinal progenitor cells and balanced retinal differentiation.	CHAT POU4F2 TFAP2A	4.90e-05	30	82	3	29137925
Pubmed	New mouse lines for the analysis of neuronal morphology using CreER(T)/loxP-directed sparse labeling.	CHAT POU4F2	5.47e-05	5	82	2	19924248
Pubmed	Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.	CHAT POU4F2 TFAP2A	7.17e-05	34	82	3	26949938
Pubmed	The ulcerative colitis marker protein WAFL interacts with accessory proteins in endocytosis.	TTBK2 TFAP2A	8.19e-05	6	82	2	20376207
Pubmed	An action potential initiation mechanism in distal axons for the control of dopamine release.	CACNA1E CHAT	8.19e-05	6	82	2	35324301
Pubmed	AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle.	POU4F2 TFAP2A	8.19e-05	6	82	2	9918694
Pubmed	Brn3b/Brn3c double knockout mice reveal an unsuspected role for Brn3c in retinal ganglion cell axon outgrowth.	CHAT POU4F2	8.19e-05	6	82	2	11807038
Pubmed	A Chrnb3-Cre BAC transgenic mouse line for manipulation of gene expression in retinal ganglion cells.	CHAT TFAP2A	1.14e-04	7	82	2	31087513
Pubmed	Requirement for math5 in the development of retinal ganglion cells.	CHAT POU4F2	1.14e-04	7	82	2	11156601
Pubmed	Abnormalities of caudal pharyngeal pouch development in Pbx1 knockout mice mimic loss of Hox3 paralogs.	FOXN1 TFAP2A	1.14e-04	7	82	2	15581866
Pubmed	Humanized mice in translational biomedical research.	FOXN1 MCPH1	1.14e-04	7	82	2	17259968
Pubmed	Fras1 deficiency results in cryptophthalmos, renal agenesis and blebbed phenotype in mice.	COL6A3 COL7A1	1.52e-04	8	82	2	12766770
Pubmed	Dlx2 homeobox gene transcriptional regulation of Trkb neurotrophin receptor expression during mouse retinal development.	CHAT POU4F2	1.96e-04	9	82	2	18086710
Pubmed	Pou3f1 orchestrates a gene regulatory network controlling contralateral retinogeniculate projections.	CHAT POU4F2	1.96e-04	9	82	2	37590135
Pubmed	Semaphorin 6A in Retinal Ganglion Cells Regulates Functional Specialization of the Inner Retina.	PLXNA4 CHAT	1.96e-04	9	82	2	38014224
Pubmed	Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae.	MOGS CHAT POU4F2	2.15e-04	49	82	3	31609468
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	CACNA1E BBX HGH1 PDE4DIP AKAP12	2.32e-04	233	82	5	37704626
Pubmed	Characterization of retinal ganglion cell, horizontal cell, and amacrine cell types expressing the neurotrophic receptor tyrosine kinase Ret.	CHAT POU4F2	2.44e-04	10	82	2	29218725
Pubmed	Forkhead Box Protein P1 Is Dispensable for Retina but Essential for Lens Development.	CHAT POU4F2	2.44e-04	10	82	2	28384713
Pubmed	Deficiency of CPEB2-Confined Choline Acetyltransferase Expression in the Dorsal Motor Nucleus of Vagus Causes Hyperactivated Parasympathetic Signaling-Associated Bronchoconstriction.	CPEB2 CHAT	2.44e-04	10	82	2	27810937
Pubmed	An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.	SEMA3B PLXNA4 CHAT	2.57e-04	52	82	3	26633812
Pubmed	GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing.	OTOF CHAT	2.98e-04	11	82	2	30275816
Pubmed	Requirement for Brn-3.0 in differentiation and survival of sensory and motor neurons.	CHAT POU4F2	2.98e-04	11	82	2	8955272
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	KY TBC1D4 MOGS MCPH1 CENPF FAM120C PLXNA4 GAL3ST2	3.48e-04	736	82	8	29676528
Pubmed	Progesterone induced Warburg effect in HEK293 cells is associated with post-translational modifications and proteasomal degradation of progesterone receptor membrane component 1.	TTBK2 PGRMC1 MPRIP	3.55e-04	58	82	3	31067491
Pubmed	On and off retinal circuit assembly by divergent molecular mechanisms.	PLXNA4 CHAT	3.57e-04	12	82	2	24179230
Pubmed	Differential expression of Sonic hedgehog along the anterior-posterior axis regulates patterning of pharyngeal pouch endoderm and pharyngeal endoderm-derived organs.	FOXN1 TFAP2A	3.57e-04	12	82	2	15680353
Pubmed	Deletion of Sema3a or plexinA1/plexinA3 causes defects in sensory afferent projections of statoacoustic ganglion neurons.	SEMA3B PLXNA4	3.57e-04	12	82	2	23991118
Pubmed	AP-2alpha knockout mice exhibit optic cup patterning defects and failure of optic stalk morphogenesis.	POU4F2 TFAP2A	3.57e-04	12	82	2	20150232
Pubmed	Loss of LMO4 in the retina leads to reduction of GABAergic amacrine cells and functional deficits.	CHAT POU4F2	3.57e-04	12	82	2	20949055
Pubmed	Functional assembly of accessory optic system circuitry critical for compensatory eye movements.	PLXNA4 POU4F2	4.21e-04	13	82	2	25959730
Pubmed	Cyclin-dependent kinase 5/p35 contributes synergistically with Reelin/Dab1 to the positioning of facial branchiomotor and inferior olive neurons in the developing mouse hindbrain.	CHAT POU4F2	4.21e-04	13	82	2	12019323
Pubmed	An Airway Protection Program Revealed by Sweeping Genetic Control of Vagal Afferents.	PIEZO2 CHAT	4.21e-04	13	82	2	32259485
Pubmed	Dynamic expression of transcription factor Brn3b during mouse cranial nerve development.	CHAT POU4F2	4.21e-04	13	82	2	26356988
Pubmed	Ikaros confers early temporal competence to mouse retinal progenitor cells.	IKZF2 POU4F2	4.21e-04	13	82	2	18940586
Pubmed	Deficiency of the neurodevelopmental disorder-associated gene Cyfip2 alters the retinal ganglion cell properties and visual acuity.	CHAT TFAP2A	4.21e-04	13	82	2	34508581
Pubmed	Localization of human cadherin genes to chromosome regions exhibiting cancer-related loss of heterozygosity.	CDH11 CDH15	4.21e-04	13	82	2	9615235
Pubmed	Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool.	PDE4DIP TACC2	4.21e-04	13	82	2	17920017
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	CACNA1E CCDC13 CENPF FAM120C SVIL PDE4DIP CDH11 AKAP12 MPRIP	4.43e-04	963	82	9	28671696
Pubmed	DDX39B facilitates the malignant progression of hepatocellular carcinoma via activation of SREBP1-mediated de novo lipid synthesis.	SVIL MYO18A MPRIP	4.53e-04	63	82	3	37052853
Pubmed	DSCAM and DSCAML1 function in self-avoidance in multiple cell types in the developing mouse retina.	CHAT POU4F2	4.91e-04	14	82	2	19945391
Pubmed	A midline switch of receptor processing regulates commissural axon guidance in vertebrates.	SEMA3B PLXNA4	4.91e-04	14	82	2	20159958
Pubmed	Expression of the LIM-homeodomain protein Isl1 in the developing and mature mouse retina.	CHAT POU4F2	4.91e-04	14	82	2	17480014
Pubmed	Identification of novel Ack1-interacting proteins and Ack1 phosphorylated sites in mouse brain by mass spectrometry.	SVIL MYO18A MPRIP	5.43e-04	67	82	3	29254152
Pubmed	Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice.	FOXN1 TFAP2A	5.65e-04	15	82	2	21177346
Pubmed	Formation of retinal direction-selective circuitry initiated by starburst amacrine cell homotypic contact.	CHAT TFAP2A	5.65e-04	15	82	2	29611808
Pubmed	Trio controls the mature organization of neuronal clusters in the hindbrain.	POU4F2 CDH11	5.65e-04	15	82	2	17898204
Pubmed	Cas adaptor proteins organize the retinal ganglion cell layer downstream of integrin signaling.	CHAT POU4F2	5.65e-04	15	82	2	24559672
Pubmed	Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice.	FOXN1 TFAP2A	5.65e-04	15	82	2	19855134
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	SEMA3B OBSL1 CHAT LRIT1	5.98e-04	162	82	4	25826454
Pubmed	Pushing the envelope of retinal ganglion cell genesis: context dependent function of Math5 (Atoh7).	POU4F2 TFAP2A	6.45e-04	16	82	2	22609278
Pubmed	Leucine-Rich Repeats and Transmembrane Domain 2 Controls Protein Sorting in the Striatal Projection System and Its Deficiency Causes Disturbances in Motor Responses and Monoamine Dynamics.	ADORA2A CHAT	6.45e-04	16	82	2	35615067
Pubmed	Cadherin expression in the developing mouse olfactory system.	CDH11 CDH15	6.45e-04	16	82	2	17278136
Pubmed	Optic chiasm presentation of Semaphorin6D in the context of Plexin-A1 and Nr-CAM promotes retinal axon midline crossing.	SEMA3B PLXNA4	6.45e-04	16	82	2	22632726
Pubmed	The circadian clock gene Bmal1 is required to control the timing of retinal neurogenesis and lamination of Müller glia in the mouse retina.	CHAT POU4F2	6.45e-04	16	82	2	31002540
Pubmed	Piezo2 senses airway stretch and mediates lung inflation-induced apnoea.	PIEZO2 CHAT	6.45e-04	16	82	2	28002412
Pubmed	Expression of the semaphorins Sema 3D and Sema 3F in the developing parathyroid and thymus.	SEMA3B PLXNA4	6.45e-04	16	82	2	18489001
Pubmed	Primary Autosomal Recessive Microcephalies and Seckel Syndrome Spectrum Disorders – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY	MCPH1 CEP152	6.45e-04	16	82	2	20301772
Pubmed	Balance between BDNF and Semaphorins gates the innervation of the mammary gland.	SEMA3B PLXNA4	6.45e-04	16	82	2	30628891
Pubmed	BARHL2 differentially regulates the development of retinal amacrine and ganglion neurons.	CHAT POU4F2	6.45e-04	16	82	2	19339595
Pubmed	Jmjd3 Plays Pivotal Roles in the Proper Development of Early-Born Retinal Lineages: Amacrine, Horizontal, and Retinal Ganglion Cells.	POU4F2 TFAP2A	7.30e-04	17	82	2	32986815
Pubmed	Semaphorin signaling facilitates cleft formation in the developing salivary gland.	SEMA3B PLXNA4	7.30e-04	17	82	2	17626059
Pubmed	Ezh2 maintains retinal progenitor proliferation, transcriptional integrity, and the timing of late differentiation.	POU4F2 TFAP2A	8.20e-04	18	82	2	25989023
Pubmed	Frizzled3 is required for the development of multiple axon tracts in the mouse central nervous system.	CHAT POU4F2	8.20e-04	18	82	2	24799694
Pubmed	Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons.	POU4F2 TFAP2A	8.20e-04	18	82	2	18987029
Pubmed	Onecut1 and Onecut2 transcription factors operate downstream of Pax6 to regulate horizontal cell development.	POU4F2 TFAP2A	8.20e-04	18	82	2	25794677
Pubmed	A multidimensional coding architecture of the vagal interoceptive system.	PIEZO2 CHAT	8.20e-04	18	82	2	35296859
Pubmed	Loss of the neurodevelopmental gene Zswim6 alters striatal morphology and motor regulation.	ADORA2A CHAT	9.15e-04	19	82	2	28433741
Pubmed	E-cadherin and APC compete for the interaction with beta-catenin and the cytoskeleton.	CDH11 CDH15	1.01e-03	20	82	2	7806582
Pubmed	Genetic dissection of the function of hindbrain axonal commissures.	CHAT POU4F2	1.01e-03	20	82	2	20231872
Pubmed	Runx1 expression defines a subpopulation of displaced amacrine cells in the developing mouse retina.	CHAT POU4F2	1.01e-03	20	82	2	16026391
Pubmed	Altered visual function and interneuron survival in Atrx knockout mice: inference for the human syndrome.	CHAT POU4F2	1.01e-03	20	82	2	19088125
Pubmed	The LIM homeobox gene Isl1 is required for the correct development of the striatonigral pathway in the mouse.	IKZF2 CHAT	1.01e-03	20	82	2	24082127
Pubmed	Subtype specification of GABAergic amacrine cells by the orphan nuclear receptor Nr4a2/Nurr1.	POU4F2 TFAP2A	1.12e-03	21	82	2	19692620
Pubmed	Prdm13 regulates subtype specification of retinal amacrine interneurons and modulates visual sensitivity.	POU4F2 TFAP2A	1.12e-03	21	82	2	25995483
Pubmed	Immunomic analysis of human sarcoma.	HAUS8 TBC1D4	1.12e-03	21	82	2	12601173
Interaction	TMOD1 interactions	HAUS8 TBC1D4 SVIL MYO18A CEP152 TFAP2A MPRIP	3.26e-06	161	79	7	int:TMOD1
Cytoband	5q31	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	5.62e-05	115	82	4	5q31
Cytoband	Ensembl 112 genes in cytogenetic band chr5q31	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 PCDH1	2.02e-04	298	82	5	chr5q31
GeneFamily	Clustered protocadherins	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	2.47e-05	64	48	4	20
Coexpression	LIU_OVARIAN_CANCER_TUMORS_AND_XENOGRAFTS_XDGS_UP	DDX12P PLXNA4 RASSF10 POMK DDX11L8 DDX11	1.16e-06	108	82	6	MM1334
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	PRUNE2 COL6A3 PDE3A PLXNA4 CDH11 AKAP12	1.28e-06	187	82	6	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	LA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PRUNE2 CACNA1E SVIL PDE4DIP TACC2 PRKAG2	1.32e-06	188	82	6	6d249fe92d51a19da19ec14bb2262d394255d577
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL7A1 LURAP1 RASSF10 MPPED2 TFAP2A MPPED1	1.63e-06	195	82	6	6c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KY CENPF PRKAG2 MPPED2 TFAP2A	1.00e-05	155	82	5	8b524c65fa5c901f70c7caae4ec7fd2859eaf227
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_low-phase\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	KY CENPF PRKAG2 MPPED2 TFAP2A	1.00e-05	155	82	5	7fe8b8c0c8a9e3190cfd52d3934509e6780e1717
ToppCell	368C-Myeloid-Monocyte-CD16+_Monocyte\|368C / Donor, Lineage, Cell class and subclass (all cells)	COL7A1 AP1M2 RASSF10 PCDH1 NOD2	1.03e-05	156	82	5	25b0936960be4955b6a6d6b8a867fdd4be548f05
ToppCell	Multiple_Sclerosis-Lymphocyte-T_NK-Treg\|Multiple_Sclerosis / Disease, Lineage and Cell Type	IL10RA RNF214 IKZF2 TBC1D4 MPRIP	1.24e-05	162	82	5	975d52e3cc101e7592425128e1099d30847a8a42
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL6A3 PIEZO2 PCDHGA5 CDH11 AKAP12	1.40e-05	166	82	5	65dafed953b01a9830b54309af75c7a561e88336
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	PRUNE2 PDE3A LURAP1 MPPED2 AKAP12	1.44e-05	167	82	5	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	Bronchial_Biopsy-Immune-Mast_cells\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	PCDHGA10 MYO18A PLXNA4 CDH11 AKAP12	1.48e-05	168	82	5	45ccc0cb42d21f4853190e8e9ed9a54aefefe738
ToppCell	(7)_MNP-(7)_DC_activated\|(7)_MNP / Spleen cell shreds - cell class (v1) and cell subclass (v1)	ADORA2A PIEZO2 TBC1D4 GPR153 TMCC2	1.57e-05	170	82	5	4ab495b38a071fa8207331df2ce0d78a2dcd034e
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	IL10RA CENPF SCG3 ARHGAP45 NOD2	1.66e-05	172	82	5	ef33b5e0515c6d29fb6d9a673011c1b68ef264f3
ToppCell	droplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TBC1D4 PDE4DIP PLXNA4 GAL3ST2 BAHCC1	1.75e-05	174	82	5	7be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCell	droplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TBC1D4 PDE4DIP PLXNA4 GAL3ST2 BAHCC1	1.80e-05	175	82	5	1b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 HK2 CDH11 AKAP12 MPRIP	1.80e-05	175	82	5	910a075ccaf79de22338ecf321fa0a867f3d7d75
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 HK2 CDH11 AKAP12 MPRIP	1.80e-05	175	82	5	f0c2eb82e17e8aec2cfa5d83169178f409cc1abc
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TBX15 COL6A3 COL7A1 PCDHGA5 SCG3	2.01e-05	179	82	5	98c0c5c8034ae8a4b3ceea7fd1d0386ee5f89d09
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PIEZO2 CDH11 MPPED1 AKAP12	2.06e-05	180	82	5	280ff5c8f292be1b88120db5ff1788b750644856
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PIEZO2 CDH11 MPPED1 AKAP12	2.06e-05	180	82	5	fdbd7c22044d9328a1e06e2f9a4451529d1df767
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	PRUNE2 PDE3A SVIL CDH11 AKAP12	2.06e-05	180	82	5	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	3'_v3-bone_marrow-Mast-Mast_cells\|bone_marrow / Manually curated celltypes from each tissue	KY PDE3A IKZF2 OBSL1 AKAP12	2.12e-05	181	82	5	30ec4635474ee0f0ea1415ec0ba7f008d97e8c1a
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNK1 CACNA1E CCDC13 CENPF SVIL	2.17e-05	182	82	5	d1c3cc2942faec7527a3c25869fd65c17899e5e4
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNK1 CACNA1E CCDC13 CENPF SVIL	2.17e-05	182	82	5	92f83f29e358000cd86a709eb8b6199761ffe8bd
ToppCell	5'-Airway_Nasal-Epithelial-Airway_epithelium-brush_cell_of_trachebronchial_tree-Tuft-Tuft_L.0.7.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TNK1 CACNA1E CCDC13 CENPF SVIL	2.17e-05	182	82	5	02baca9a72c7b559c3e452693b3b134af804c868
ToppCell	wk_15-18-Mesenchymal-Myofibro_&_SMC-Early_airway_SMC_2\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PRUNE2 SVIL PLXNA4 POU4F2 TACC2	2.23e-05	183	82	5	a1d4f25e13f5b9e92a9ca0a804a7bed5df8fb2fe
ToppCell	LV-15._Ventricular_Cardiomyocyte_III\|LV / Chamber and Cluster_Paper	PDE3A TBC1D4 SVIL PDE4DIP TACC2	2.29e-05	184	82	5	ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCell	facs-BAT-Fat-24m-Epithelial-Epcam+\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNF186 HK2 SPDEF CHAT GAL3ST2	2.41e-05	186	82	5	b18d7398279a2d42414318aeb70514fd402f5a0a
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteochondral_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TBX15 COL6A3 PCDHGA2 CDH11 CDH15	2.54e-05	188	82	5	ed92cddf47defea2f904d36c7ae05ffa323349a9
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E PDE3A RASSF10 CDH11 DNAH1	2.60e-05	189	82	5	8e583ec4df0f5b79ce5211cc99ecd8616d180bde
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.60e-05	189	82	5	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	MS-Treg-CD4_Treg\|MS / Condition, Cell_class and T cell subcluster	IL10RA RNF214 IKZF2 TBC1D4 MPRIP	2.60e-05	189	82	5	b1310eed6113b3536868340a5b2b2587ad377fa9
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	PDE3A TBC1D4 SVIL PDE4DIP TACC2	2.60e-05	189	82	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	MS-Treg\|MS / Condition, Cell_class and T cell subcluster	IL10RA RNF214 IKZF2 TBC1D4 MPRIP	2.60e-05	189	82	5	3fa79242fb3dba4a3f52276da0124ba260423fb6
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|World / Chamber and Cluster_Paper	PDE3A SVIL PDE4DIP TACC2 PRKAG2	2.60e-05	189	82	5	0a82931b5f6c0a6427ca3edd5e2235ac49099d40
ToppCell	droplet-Heart-nan-3m-Endothelial-endocardial_endothelial_cells\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1E PDE3A RASSF10 CDH11 DNAH1	2.60e-05	189	82	5	fb2253b8463d08b3d28e952a31a23dea2c2d986b
ToppCell	RV-15._Ventricular_Cardiomyocyte_III\|RV / Chamber and Cluster_Paper	PDE3A SVIL PDE4DIP TACC2 PRKAG2	2.67e-05	190	82	5	93c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_anti-infl-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	IL10RA HGH1 NANS DNAH1 BAHCC1	2.67e-05	190	82	5	63018acb7ad80415e861643162abdc2e55968ee4
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.67e-05	190	82	5	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	Control-Fibroblasts\|Control / group, cell type (main and fine annotations)	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	2.67e-05	190	82	5	3a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	PDE3A TBC1D4 SVIL PDE4DIP TACC2	2.67e-05	190	82	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.67e-05	190	82	5	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.74e-05	191	82	5	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	PDE3A TBC1D4 SVIL PDE4DIP TACC2	2.74e-05	191	82	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	CACNA1E SVIL PDE4DIP TACC2 PRKAG2	2.74e-05	191	82	5	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.81e-05	192	82	5	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.81e-05	192	82	5	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.81e-05	192	82	5	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.81e-05	192	82	5	3d0cb19f037f604253d7d728689aeaa94251e92b
ToppCell	LPS-IL1RA-Stromal_mesenchymal\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.81e-05	192	82	5	4e47a02007f562f29ba5910df64d32a0167d0bd1
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIEZO2 TBC1D4 MYO18A ARHGAP45 HYDIN	2.81e-05	192	82	5	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.81e-05	192	82	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_SST-Inh_L3-5_SST_MAFB\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL7A1 NEK3 PIEZO2 OTOF MPPED1	2.88e-05	193	82	5	c7e9e6e4bf5e07c9cbdf1aa7c8828f4b2500e3ff
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-basal_intermediate_\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	FOXN1 COL7A1 SPDEF TFAP2A MPPED1	2.88e-05	193	82	5	83d2dd823808a2b5ca1a6889eefb541ec042b24c
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.88e-05	193	82	5	fb28717fadd06c3840636d25409ce80c9254bd34
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A PLXNA4 CDH11 AKAP12	2.95e-05	194	82	5	cf0244a29934e515446ac917d3c30672b460fb04
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	2.95e-05	194	82	5	240d122dcb9dd1ab2867503ad85869853adcacae
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.95e-05	194	82	5	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	2.95e-05	194	82	5	ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell	RA-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PRUNE2 SVIL PDE4DIP TACC2 PRKAG2	2.95e-05	194	82	5	89812fb164065041357bb37a3c2d87028ec3de4e
ToppCell	LPS-antiTNF-Stromal_mesenchymal\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.95e-05	194	82	5	6e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	2.95e-05	194	82	5	90efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	2.95e-05	194	82	5	df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 PDE3A PIEZO2 PLXNA4 CDH11	2.95e-05	194	82	5	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A PLXNA4 CDH11 AKAP12	2.95e-05	194	82	5	ba7f971fb9a19423602da60770f23d9fead4a451
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	TBC1D4 SVIL PDE4DIP TACC2 PRKAG2	2.95e-05	194	82	5	c3535f7cc0076653c72db582047cff053c322397
ToppCell	COVID-19-Heart-CM_1\|Heart / Disease (COVID-19 only), tissue and cell type	PDE3A TBC1D4 SVIL PDE4DIP TACC2	3.02e-05	195	82	5	f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	PDE3A TBC1D4 SVIL PDE4DIP TACC2	3.02e-05	195	82	5	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCG3 PLXNA4 POU4F2 PCDH1 TFAP2A	3.02e-05	195	82	5	9fea1ddb68da83ca43dd8006c9e51295b1817f0e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.02e-05	195	82	5	44d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SCG3 PLXNA4 POU4F2 PCDH1 TFAP2A	3.10e-05	196	82	5	9afd0a7135028a446f06bb68f334e79b8f171b45
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.10e-05	196	82	5	2b36b9a40fe415917afccff99ad9c3474e087d0d
ToppCell	Children_(3_yrs)-Mesenchymal\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.10e-05	196	82	5	bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 PRUNE2 COL6A3 PDE3A AKAP12	3.18e-05	197	82	5	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL7A1 LURAP1 MPPED2 TFAP2A MPPED1	3.18e-05	197	82	5	107cb153ea7fc74bbd244dbb9d0499c0a8506724
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 PIEZO2 SVIL CDH11 AKAP12	3.18e-05	197	82	5	6668f0da54f3bf96769275e668cd57e00b8a5ef9
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	COL6A3 PDE3A CDH11 AKAP12 MPRIP	3.18e-05	197	82	5	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 PIEZO2 SVIL CDH11 AKAP12	3.18e-05	197	82	5	7c275a2ac24a9a4f83fceda93a067e754837102f
ToppCell	Adult-Mesenchymal\|Adult / Lineage, Cell type, age group and donor	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.25e-05	198	82	5	26e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCell	Fetal_29-31_weeks-Mesenchymal\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.25e-05	198	82	5	21cf4d81386761d09d0f6829c01c198e5524176d
ToppCell	18-Airway-Mesenchymal-Mesenchyme_RSPO2+\|Airway / Age, Tissue, Lineage and Cell class	COL6A3 PIEZO2 CENPF CDH11 AKAP12	3.33e-05	199	82	5	7ac35e8f45dcdc702422dabd8f3e4d03e2bf61af
ToppCell	Mesenchymal\|World / Lineage, Cell type, age group and donor	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.33e-05	199	82	5	4bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_perichondrial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	KY COL6A3 PDE3A MPPED2 CDH11	3.33e-05	199	82	5	abd6117f8a3d7e798d8471c16d97b34aaf50fc9c
ToppCell	Bronchial-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.41e-05	200	82	5	389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCell	wk_20-22-Mesenchymal-Fibroblast-intermediate_fibro\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	COL6A3 PIEZO2 PGRMC1 CDH11 AKAP12	3.41e-05	200	82	5	d769723f8fcb37d9b86589e0c41c1d7f16393cfe
ToppCell	Parenchymal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.41e-05	200	82	5	cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	PRUNE2 COL6A3 SVIL PLXNA4 TACC2	3.41e-05	200	82	5	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	Tracheal-NucSeq-Stromal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.41e-05	200	82	5	c318d14bd6fd6f42c597eb55ac9e2f48008aeb9b
ToppCell	MS-Multiple_Sclerosis-Lymphocyte-T/NK-Treg\|Multiple_Sclerosis / Disease, condition lineage and cell class	IL10RA RNF214 IKZF2 TBC1D4 MPRIP	3.41e-05	200	82	5	8702758a62fa923c2e9012c0aa8b3b492a44f8fb
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.41e-05	200	82	5	311fab076f2ceb258e3970eb21e39344b894042a
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TBX15 COL6A3 PDE3A AKAP12 MPRIP	3.41e-05	200	82	5	fc2fc3bfcf1ad9bfb9fe07bbed8068126930bee6
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	TBX15 COL6A3 PIEZO2 SCG3 CDH11	3.41e-05	200	82	5	07641f476cb1a131c2a50258b88cc13bb38c8379
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-3\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	TBX15 COL6A3 PIEZO2 SCG3 CDH11	3.41e-05	200	82	5	343fa6ba1f52d816d2e41466f674ff8360aecd81
ToppCell	Parenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL6A3 PDE3A PIEZO2 CDH11 AKAP12	3.41e-05	200	82	5	74e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TBX15 COL6A3 PIEZO2 SCG3 CDH11	3.41e-05	200	82	5	d0c00cdd52c2e001aec9b935f4e981ba77d0386a
ToppCell	RV-03._Atrial_Cardiomyocyte\|World / Chamber and Cluster_Paper	PDE3A SVIL PDE4DIP TACC2	7.64e-05	122	82	4	1cb1dd03b2aaedbe04f3ed907568c3b7f54767b3
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TBX15 PCDHGB6 PCDHGA10 TFAP2A	8.66e-05	126	82	4	f1f24b06d301c266226d1a59dd28585f5ac68f29
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TBX15 PCDHGB6 PCDHGA10 TFAP2A	8.66e-05	126	82	4	fe6900eb37e4f09465a1276586c73dd38545fa2a
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TBX15 PCDHGB6 PCDHGA10 TFAP2A	8.66e-05	126	82	4	3d507f829882d043f633db2612b76936e2042445
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TBX15 PCDHGB6 PCDHGA10 TFAP2A	8.66e-05	126	82	4	1ac4cc747e466bc79e33b97608b19ad29a7a6a41
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_TIP-Dcn_1-Dcn_1_1-Endothelial_Tip.Dcn_(Dcn)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TBX15 PCDHGB6 PCDHGA10 TFAP2A	8.66e-05	126	82	4	2de551d7a8765afec1da8852727c79fec90f45f8
Disease	Warsaw breakage syndrome (implicated_via_orthology)	DDX12P DDX11L8 DDX11	1.78e-08	3	78	3	DOID:0060535 (implicated_via_orthology)
Disease	mental development measurement	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	5.48e-07	25	78	4	EFO_0008230
Disease	progression free survival, chronic lymphocytic leukemia	SPDEF TACC2	6.90e-06	2	78	2	EFO_0000095, EFO_0004920
Disease	childhood trauma measurement, alcohol consumption measurement	PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2	3.84e-05	71	78	4	EFO_0007878, EFO_0007979
Disease	Primary ciliary dyskinesia	CENPF HYDIN DNAH1	1.19e-04	36	78	3	cv:C0008780
Disease	mean platelet volume	TBC1D4 BBX PCDHGB6 PCDHGA10 PCDHGA5 PCDHGA2 TMCC2 SVIL ARHGAP45 MPRIP	3.49e-04	1020	78	10	EFO_0004584
Disease	cognitive function measurement	IL10RA CACNA1E RNF214 NEK3 VAC14 BBX PCDHGA5 SCG3 PLXNA4 PRKAG2 PCDH1 HYDIN	3.68e-04	1434	78	12	EFO_0008354
Disease	unipolar depression, multiple sclerosis	BBX RASSF10	4.48e-04	12	78	2	EFO_0003761, MONDO_0005301
Disease	glycodeoxycholate measurement	COL7A1 SVIL	6.15e-04	14	78	2	EFO_0010493
Disease	Autosomal recessive primary microcephaly	MCPH1 CEP152	7.08e-04	15	78	2	cv:C3711387
Disease	hydrocephalus (implicated_via_orthology)	POMK HYDIN	1.15e-03	19	78	2	DOID:10908 (implicated_via_orthology)
Disease	Hodgkins lymphoma	DDX12P CHAT PGRMC1	1.35e-03	82	78	3	EFO_0000183
Disease	Seckel syndrome	CENPF CEP152	1.54e-03	22	78	2	C0265202
Disease	Primary microcephaly	MCPH1 CEP152	1.54e-03	22	78	2	C0431350
Disease	Autosomal Recessive Primary Microcephaly	MCPH1 CEP152	1.54e-03	22	78	2	C3711387
Disease	Sarcosine measurement	PCDHGA5 PCDHGA2	1.68e-03	23	78	2	EFO_0021668
Disease	nevus count, cutaneous melanoma	TMCC2 CDH15 AKAP12	1.83e-03	91	78	3	EFO_0000389, EFO_0004632

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLLDGDLEGSGKHSS	PRKAG2	46	Q9UGJ0
GGPRSTHALDLEAEE	BAHCC1	741	Q9P281
GIHPSDSEGELNIEL	CEP152	491	O94986
GLPSLGVSDHKAEVD	C16orf86	276	Q6ZW13
EEEGALAPLLSHGQV	AP1M2	41	Q9Y6Q5
LLLAGEHALGTPEVS	BBX	211	Q8WY36
AGGLDEADTPLVLPH	CACNA1E	996	Q15878
GNTGLPDVELLSHEL	ADORA2A	376	P29274
GETLEPAGAHLVLEE	AKAP12	1441	Q02952
GTKSVPEDDGHALLA	AKAP12	1671	Q02952
EDLLHGPHALSSGLG	TFAP2A	131	P05549
LSLADKGSLPAGEHS	ARRDC1	71	Q8N5I2
LHTLELTVAPDGAPG	RASSF10	436	A6NK89
DGGNPSLSTDAHILL	PCDHGA2	426	Q9Y5H1
TVHDLLLTALDGGDP	PCDHGA5	206	Q9Y5G8
RSHSLILTALDGGDP	PCDHGB6	206	Q9Y5F9
PADGAEHGLLLTAAL	OBSL1	61	O75147
EHGLLLTAALPTDAG	OBSL1	66	O75147
LLHTGDFTELGLPSE	MPPED2	81	Q15777
IAPVHLSSEDGGDRL	MPRIP	656	Q6WCQ1
EGAGPDVVEDISHLL	ARHGAP45	106	Q92619
KGHDDDLTPLEGSLE	MCPH1	536	Q8NEM0
EHQLEPGDTLAGLAL	LYSMD1	41	Q96S90
NVLASLHGDDGPITE	KY	491	Q8NBH2
TPDGTEHGEFLALDL	HK2	71	P52789
HELTSDLDGAGIPFL	PLXNA4	1301	Q9HCM2
IHHLVLTASDGGDPL	PCDHGA10	211	Q9Y5H3
LGHSLDTPLDIDIAG	PCDH1	826	Q08174
ELDLPSGDHCEAGLL	MYO18A	1071	Q92614
GEDHLLSLPAAGVVL	PDE3A	181	Q14432
GEAHGLITDLLADPS	PDE3A	351	Q14432
ADPSDLESGGLLHEI	PGRMC1	11	O00264
GEALPAHSGAPLLVE	CTDSP1	51	Q9GZU7
GSGEDLAALAHLVLP	GPR153	416	Q6NV75
LGVPLEEEEGLLSSH	LMLN2	371	A0A1B0GTW7
GALLLPGASSTGHDL	LURAP1	41	Q96LR2
PELKNLDLHGSTDSG	IL10RA	306	Q13651
EEEARLLETGTGPLH	DDX11	71	Q96FC9
LLETGTGPLHDEKDE	DDX11	76	Q96FC9
DVLIHAGDFTELGLP	MPPED1	111	O15442
LLEGHGTAPPDLDLS	HAUS8	91	Q9BT25
IRGHDEGSSLEEPLI	IKZF2	71	Q9UKS7
TLLGLPAVSHLDSGD	LRIT1	311	Q9P2V4
VDGGHDSVILDPERL	NEK3	456	P51956
EHLGEAEVAAELGPL	MOGS	616	Q13724
SEEEEAEHGLLLGQP	NOL7	26	Q9UMY1
EFLLLGLSDGPHTEQ	OR2D2	11	Q9H210
LHSDLELDTPLFGGQ	GAL3ST2	31	Q9H3Q3
SGDPLLESVGLHEPL	DNAH1	711	Q9P2D7
AHLDPENITLSGEGI	HYDIN	1476	Q4G0P3
SSLFPIDDGLLDDGH	CPEB2	291	Q7Z5Q1
DDSGLLHGELVEDIP	CENPF	1351	P49454
LEVSDGLSLLHAGEP	CCDC13	51	Q8IYE1
DGHSKDGLALPSAEL	COL6A3	151	P12111
EEEARLLETGTGPLH	DDX11L8	71	A8MPP1
LLETGTGPLHDEKDE	DDX11L8	76	A8MPP1
EASLGDGEPHIPSLL	FAM120C	571	Q9NX05
PVLVGRLHSDIDSGD	CDH11	71	P55287
EEARLLETGTGPLHD	DDX12P	91	Q92771
SSTPLGELFDHGLDS	SELENOI	116	Q9C0D9
VLGPELSSYHLDGLE	COL7A1	911	Q02388
LLLGATDEDLPPHGA	CDH15	501	P55291
DHLAIRLGDGLDPDS	OTOF	206	Q9HC10
DPGLHETLLAADPGL	HGH1	91	Q9BTY7
PADLAAGHPSLVGED	RNF186	126	Q9NXI6
GPLDGPDLQASHSEL	VAC14	481	Q08AM6
LGHSEVGDPSLDARD	PRUNE2	2636	Q8WUY3
EDGAGLEDAASHLPG	TMCC2	16	O75069
ALHVGDGSSDPEVLL	SVIL	186	O95425
QALEGELLEHLSPGL	POU4F2	186	Q12837
HDTLLPDGDLGTDLD	FOXN1	516	O15353
GPLGDTEDAAAHGLE	TBX15	51	Q96SF7
KGSDHSASLEPGELA	NANS	246	Q9NR45
PDISSFLLGHIEGSD	POMK	286	Q9H5K3
DAPGGVELSDTHRAL	CHAT	391	P28329
AGEEGDTSLRESLHP	RNF214	116	Q8ND24
DEEERASVLLGHSPG	NOD2	11	Q9HC29
LGLEELFSTPGHLND	NOD2	276	Q9HC29
GSRPSAEGLLLEELH	SEMA3B	466	Q13214
DLVPGGLTLEEHSLE	SPDEF	106	O95238
SEDLPGHQGDLSTFL	TTBK2	886	Q6IQ55
RESGLDTIDEHPGAA	PIEZO2	1716	Q9H5I5
ELAHLAGPGSPEAEE	TSSC4	256	Q9Y5U2
TAEADASGLPHKLGE	TACC2	651	O95359
CLPEEADGTDTHLGL	TBC1D4	266	O60343
SHLEGLLQEAGPSEA	TNK1	371	Q13470
DGLHQLDGTPLTAED	SCG3	136	Q8WXD2
DLGALLEQHSISLGP	NAALADL1	606	Q9UQQ1
SKPTGADLLEEHLGE	PDE4DIP	1836	Q5VU43