Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionG protein-coupled receptor activity

TPRA1 HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 ADGRL1 TSHR ADGRV1 GRM7 GALR2 GNRHR2 OR51Q1 LPAR6 TAS1R2 ADGRL2 GPR132

7.60e-0788410518GO:0004930
GeneOntologyMolecularFunctiontransporter activity

HTR1B ATP7B ATP8A2 SLC44A2 SLC6A15 SLC44A4 SLC7A6 GRM7 ATP8B2 SVOPL SLC2A5 ITPR1 ITPR2 SFXN1 SLC6A8 SLC9A3 ATP8A1 KCNT2 SLC12A4 SFXN3 LRP2 NIPA1

7.61e-07128910522GO:0005215
GeneOntologyMolecularFunctionorganic cation transmembrane transporter activity

SLC44A2 SLC44A4 SLC7A6 SFXN1 SLC6A8 SFXN3

4.98e-06831056GO:0015101
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

TPRA1 HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 ADGRL1 TSHR ADGRV1 GRM7 GALR2 GNRHR2 SORT1 TGFBR2 OR51Q1 LPAR6 TAS1R2 PTCH2 ADGRL2 GPR132

6.34e-06135310521GO:0004888
GeneOntologyMolecularFunctioncholine transmembrane transporter activity

SLC44A2 SLC44A4 SLC6A8

7.76e-0681053GO:0015220
GeneOntologyMolecularFunctiontransmembrane transporter activity

HTR1B ATP7B SLC44A2 SLC6A15 SLC44A4 SLC7A6 GRM7 SVOPL SLC2A5 ITPR1 ITPR2 SFXN1 SLC6A8 SLC9A3 ATP8A1 KCNT2 SLC12A4 SFXN3 NIPA1

1.13e-05118010519GO:0022857
GeneOntologyMolecularFunctionlatrotoxin receptor activity

ADGRL1 ADGRL2

2.74e-0521052GO:0016524
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT1A10 UGT2A2 UGT1A9 UGT2A1

3.33e-05351054GO:0015020
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

HTR1B ATP7B SLC6A15 GRM7 ITPR1 ITPR2 SLC6A8 SLC9A3 KCNT2 SLC12A4 NIPA1

3.38e-0546510511GO:0046873
GeneOntologyMolecularFunctionserotonin binding

HTR1A HTR1B HTR1D

3.89e-05131053GO:0051378
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP8A2 ATP8B2 ATP8A1

4.93e-05141053GO:0140333
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

HTR1B ATP7B SLC6A15 GRM7 ITPR1 ITPR2 SFXN1 SLC6A8 SLC9A3 ATP8A1 KCNT2 SLC12A4 SFXN3 NIPA1

6.96e-0579310514GO:0015075
GeneOntologyMolecularFunctionfloppase activity

ATP8A2 ATP8B2 ATP8A1

7.53e-05161053GO:0140328
GeneOntologyMolecularFunctioninositol 1,4,5-trisphosphate-gated calcium channel activity

ITPR1 ITPR2

8.19e-0531052GO:0005220
GeneOntologyMolecularFunctionflippase activity

ATP8A2 ATP8B2 ATP8A1

9.11e-05171053GO:0140327
GeneOntologyMolecularFunctionadenylate cyclase inhibitor activity

ADGRV1 GRM7

1.63e-0441052GO:0010855
GeneOntologyMolecularFunctiongalanin receptor activity

GALR3 GALR2

1.63e-0441052GO:0004966
GeneOntologyMolecularFunctionamine binding

HTR1A HTR1B HTR1D

1.75e-04211053GO:0043176
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

HTR1B ATP7B SLC6A15 GRM7 ITPR1 ITPR2 SLC6A8 SLC9A3 ATP8A1 KCNT2 SLC12A4 NIPA1

1.92e-0466410512GO:0008324
GeneOntologyMolecularFunctionG protein-coupled serotonin receptor activity

HTR1A HTR1B HTR1D

2.02e-04221053GO:0004993
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC6A15 SLC7A6 SFXN1 SLC6A8 SFXN3

2.32e-041051055GO:0015171
GeneOntologyMolecularFunctionphosphatidylserine flippase activity

ATP8A2 ATP8A1

2.71e-0451052GO:0140346
GeneOntologyMolecularFunctioncyclase inhibitor activity

ADGRV1 GRM7

2.71e-0451052GO:0010852
GeneOntologyMolecularFunctionlysophosphatidic acid receptor activity

LPAR4 LPAR6

2.71e-0451052GO:0070915
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP8A2 ATP8B2 ATP8A1

4.21e-04281053GO:0140326
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

HTR1B ATP7B SLC6A15 GRM7 ITPR1 ITPR2 SLC6A8 SLC9A3 KCNT2 SLC12A4 NIPA1

4.61e-0462710511GO:0022890
GeneOntologyMolecularFunctionaminophospholipid flippase activity

ATP8A2 ATP8A1

5.65e-0471052GO:0015247
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ATP7B SLC44A2 SLC6A15 SLC44A4 SLC7A6 SLC6A8 SLC9A3 ATP8A1 SLC12A4

9.30e-044771059GO:0022804
GeneOntologyMolecularFunctionL-serine transmembrane transporter activity

SFXN1 SFXN3

9.63e-0491052GO:0015194
GeneOntologyMolecularFunctionadenylate cyclase regulator activity

ADGRV1 GRM7

9.63e-0491052GO:0010854
GeneOntologyMolecularFunctionphosphatidylserine floppase activity

ATP8A2 ATP8A1

9.63e-0491052GO:0090556
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC44A2 SLC6A15 SLC44A4 SLC7A6 SLC6A8 SLC9A3 SLC12A4

9.67e-042961057GO:0015291
GeneOntologyMolecularFunctionG protein-coupled amine receptor activity

HTR1A HTR1B HTR1D

1.30e-03411053GO:0008227
GeneOntologyMolecularFunctioncalcium ion binding

DSC1 SYT2 ADGRV1 GRM7 LRP1B ITPR1 ITPR2 SYT8 LRP2 SYT5 CDH18

1.95e-0374910511GO:0005509
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

HTR1B ATP7B SLC6A15 GRM7 ITPR1 ITPR2 SLC6A8 SLC9A3 KCNT2 SLC12A4 NIPA1

2.14e-0375810511GO:0015318
GeneOntologyMolecularFunctioninositol 1,4,5 trisphosphate binding

ITPR1 ITPR2

2.39e-03141052GO:0070679
GeneOntologyMolecularFunctionintramembrane lipid transporter activity

ATP8A2 ATP8B2 ATP8A1

2.45e-03511053GO:0140303
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1B LRP2

3.13e-03161052GO:0005041
GeneOntologyMolecularFunctionbioactive lipid receptor activity

LPAR4 LPAR6

3.13e-03161052GO:0045125
GeneOntologyMolecularFunctioncalcium-dependent phospholipid binding

SYT2 SYT8 SYT5

3.89e-03601053GO:0005544
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

ITPR1 ITPR2

3.97e-03181052GO:0015278
GeneOntologyMolecularFunctioncyclase regulator activity

ADGRV1 GRM7

3.97e-03181052GO:0010851
GeneOntologyMolecularFunctionPDZ domain binding

GRM7 SLC9A3 LRP2 ADGRL2

4.06e-031231054GO:0030165
GeneOntologyMolecularFunctionglycosyltransferase activity

UGT1A10 UGT2A2 UGT1A9 ST6GAL1 ALG9 UGT2A1

4.18e-032881056GO:0016757
GeneOntologyMolecularFunctionclathrin binding

SYT2 SYT8 SYT5

4.46e-03631053GO:0030276
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC6A15 SLC44A4 SLC7A6 SFXN1 SLC6A8 SFXN3

4.54e-032931056GO:0008514
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC6A15 SLC7A6 SFXN1 SLC6A8 SFXN3

4.77e-032071055GO:0046943
GeneOntologyMolecularFunctioncalcium channel activity

HTR1B GRM7 ITPR1 ITPR2

4.81e-031291054GO:0005262
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC6A15 SLC7A6 SFXN1 SLC6A8 SFXN3

4.86e-032081055GO:0005342
GeneOntologyMolecularFunctionhexosyltransferase activity

UGT1A10 UGT2A2 UGT1A9 ALG9 UGT2A1

5.17e-032111055GO:0016758
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP7B SLC6A15 SLC6A8 SLC9A3 ATP8A1 SLC12A4

5.17e-033011056GO:0022853
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1B LRP2

5.39e-03211052GO:0030228
GeneOntologyMolecularFunctionprotein-hormone receptor activity

TSHR GNRHR2

5.91e-03221052GO:0016500
GeneOntologyMolecularFunctionantiporter activity

SLC44A2 SLC44A4 SLC7A6 SLC9A3

6.09e-031381054GO:0015297
GeneOntologyMolecularFunctionL-amino acid transmembrane transporter activity

SLC7A6 SFXN1 SFXN3

6.23e-03711053GO:0015179
GeneOntologyMolecularFunctionchloride:monoatomic cation symporter activity

SLC6A8 SLC12A4

6.45e-03231052GO:0015377
GeneOntologyMolecularFunctionamino acid:sodium symporter activity

SLC6A15 SLC6A8

6.45e-03231052GO:0005283
GeneOntologyMolecularFunctionphosphatidylserine binding

SYT2 SYT8 SYT5

6.73e-03731053GO:0001786
GeneOntologyMolecularFunctionphospholipid transporter activity

ATP8A2 ATP8B2 ATP8A1

6.99e-03741053GO:0005548
GeneOntologyBiologicalProcessregulation of lyase activity

GALR3 TSHR ADGRV1 GALR2 ADCY3 MTRR

2.17e-06731076GO:0051339
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

TPRA1 HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 ADGRL1 TSHR ADGRV1 GRM7 GALR2 ADCY3 ITPR1 GNRHR2 SORT1 OR51Q1 LPAR6 TAS1R2 ADGRL2 GPR132 HTT

2.31e-06139510722GO:0007186
GeneOntologyBiologicalProcessadenylate cyclase-modulating G protein-coupled receptor signaling pathway

HTR1A HTR1B HTR1D GALR3 ADGRL1 TSHR GRM7 GALR2 ADCY3 ADGRL2

2.41e-0628610710GO:0007188
GeneOntologyBiologicalProcesscellular glucuronidation

UGT1A10 UGT2A2 UGT1A9 UGT2A1

3.83e-06211074GO:0052695
GeneOntologyBiologicalProcessnegative regulation of lyase activity

GALR3 ADGRV1 GALR2 MTRR

4.66e-06221074GO:0051350
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting serotonin receptor signaling pathway

HTR1A HTR1B HTR1D

4.68e-0671073GO:0007198
GeneOntologyBiologicalProcessmonoatomic ion transport

HTR1A HTR1B ATP7B LMTK2 SLC6A15 GALR2 ATP8B2 AMIGO1 ITPR1 ITPR2 SFXN1 SLC6A8 SLC9A3 ATP8A1 KCNT2 SLC12A4 SFXN3 LRP2 CD63 NIPA1 HTT

6.66e-06137410721GO:0006811
GeneOntologyBiologicalProcessamino acid transport

HTR1A HTR1B SLC6A15 SLC7A6 GRM7 SFXN1 SLC6A8 SFXN3

8.10e-061951078GO:0006865
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT1A10 UGT2A2 UGT1A9 UGT2A1

9.37e-06261074GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT1A10 UGT2A2 UGT1A9 UGT2A1

9.37e-06261074GO:0006063
GeneOntologyBiologicalProcessregulation of adenylate cyclase activity

GALR3 TSHR ADGRV1 GALR2 ADCY3

1.37e-05591075GO:0045761
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger

HTR1A HTR1B HTR1D GALR3 TSHR

1.61e-05611075GO:0007187
GeneOntologyBiologicalProcessgalanin-activated signaling pathway

GALR3 GALR2

2.67e-0521072GO:0090663
GeneOntologyBiologicalProcessregulation of cyclase activity

GALR3 TSHR ADGRV1 GALR2 ADCY3

2.95e-05691075GO:0031279
GeneOntologyBiologicalProcessmetal ion transport

ATP7B LMTK2 SLC6A15 GALR2 AMIGO1 ITPR1 ITPR2 SFXN1 SLC6A8 SLC9A3 KCNT2 SLC12A4 LRP2 CD63 NIPA1 HTT

5.65e-05100010716GO:0030001
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

ATP7B SLC6A15 GALR2 ATP8B2 AMIGO1 ITPR1 ITPR2 SFXN1 SLC6A8 SLC9A3 ATP8A1 KCNT2 SLC12A4 SFXN3 CD63 NIPA1 HTT

5.88e-05111510717GO:0034220
GeneOntologyBiologicalProcessserine import into mitochondrion

SFXN1 SFXN3

7.97e-0531072GO:0140300
GeneOntologyBiologicalProcessmonoatomic cation transport

ATP7B LMTK2 SLC6A15 GALR2 AMIGO1 ITPR1 ITPR2 SFXN1 SLC6A8 SLC9A3 ATP8A1 KCNT2 SLC12A4 LRP2 CD63 NIPA1 HTT

9.26e-05115710717GO:0006812
GeneOntologyBiologicalProcessnegative regulation of adenylate cyclase activity

GALR3 ADGRV1 GALR2

1.05e-04181073GO:0007194
GeneOntologyBiologicalProcessorganic cation transport

SLC44A2 SLC6A15 SLC44A4 SLC7A6 SFXN1 SFXN3

1.10e-041451076GO:0015695
GeneOntologyBiologicalProcessnegative regulation of cyclase activity

GALR3 ADGRV1 GALR2

1.24e-04191073GO:0031280
GeneOntologyBiologicalProcessnegative regulation of amino acid transport

HTR1A HTR1B GRM7

1.69e-04211073GO:0051956
GeneOntologyBiologicalProcessfeeding behavior

HTR1A HTR1B GALR3 ATP8A2 GRM7 GALR2

2.01e-041621076GO:0007631
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC6A15 SLC7A6 SFXN1 SLC6A8 SFXN3 LRP2

2.08e-041631076GO:1905039
GeneOntologyBiologicalProcessG protein-coupled serotonin receptor signaling pathway

HTR1A HTR1B HTR1D

2.23e-04231073GO:0098664
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC6A15 SLC7A6 SFXN1 SLC6A8 SFXN3 LRP2

2.37e-041671076GO:1903825
GeneOntologyBiologicalProcessestrogen catabolic process

UGT1A10 UGT1A9

2.64e-0451072GO:0006711
GeneOntologyBiologicalProcessneutral amino acid transport

SLC6A15 SLC7A6 SFXN1 SFXN3

2.67e-04601074GO:0015804
GeneOntologyBiologicalProcesscarboxylic acid transport

HTR1A HTR1B SLC6A15 SLC7A6 GRM7 SFXN1 SLC6A8 SFXN3 LRP2

2.86e-044101079GO:0046942
GeneOntologyBiologicalProcesscalcium ion-regulated exocytosis of neurotransmitter

SYT2 SYT8 SYT5

2.87e-04251073GO:0048791
GeneOntologyBiologicalProcessorganic acid transport

HTR1A HTR1B SLC6A15 SLC7A6 GRM7 SFXN1 SLC6A8 SFXN3 LRP2

2.96e-044121079GO:0015849
GeneOntologyBiologicalProcessorganic anion transport

HTR1A HTR1B SLC6A15 SLC44A4 SLC7A6 GRM7 SFXN1 SLC6A8 SFXN3 LRP2

3.48e-0451510710GO:0015711
GeneOntologyBiologicalProcessendocytosis

GAPVD1 HTR1B HEATR5A SYT2 LRP1B SORT1 TGFBR2 SLC9A3 ATP8A1 SYT8 LRP2 CD63 SYT5

3.52e-0482710713GO:0006897
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

ATP7B SLC6A15 GALR2 AMIGO1 ITPR1 ITPR2 SLC6A8 SLC9A3 ATP8A1 KCNT2 SLC12A4 CD63 NIPA1 HTT

3.64e-0494210714GO:0098655
GeneOntologyBiologicalProcessphenylpropanoid catabolic process

UGT1A10 UGT1A9

3.95e-0461072GO:0046271
GeneOntologyBiologicalProcesscoumarin catabolic process

UGT1A10 UGT1A9

3.95e-0461072GO:0046226
GeneOntologyBiologicalProcesspositive regulation of phospholipid translocation

ATP8A2 ATP8A1

3.95e-0461072GO:0061092
GeneOntologyBiologicalProcessnegative regulation of gamma-aminobutyric acid secretion

HTR1A HTR1B

3.95e-0461072GO:0014053
GeneOntologyBiologicalProcessflavone metabolic process

UGT1A10 UGT1A9

3.95e-0461072GO:0051552
GeneOntologyBiologicalProcessgamma-aminobutyric acid transport

HTR1A HTR1B SLC6A8

4.05e-04281073GO:0015812
GeneOntologyBiologicalProcessneurotransmitter transport

HTR1B HTR1D SLC6A15 SYT2 SLC6A8 SYT8 SYT5

4.07e-042591077GO:0006836
GeneOntologyBiologicalProcessimport into cell

GAPVD1 HTR1B HEATR5A SYT2 LRP1B SLC2A5 SORT1 TGFBR2 SLC9A3 ATP8A1 SLC12A4 SYT8 LRP2 CD63 SYT5

4.27e-04107410715GO:0098657
GeneOntologyBiologicalProcesssynaptic vesicle exocytosis

HTR1B HTR1D SYT2 SYT8 SYT5

4.90e-041251075GO:0016079
GeneOntologyBiologicalProcessregulation of phospholipid translocation

ATP8A2 ATP8A1

5.50e-0471072GO:0061091
GeneOntologyBiologicalProcessaminophospholipid translocation

ATP8A2 ATP8A1

5.50e-0471072GO:0140331
GeneOntologyBiologicalProcessinner ear morphogenesis

ATP8A2 TSHR SLC44A4 TMIE FGF10

5.65e-041291075GO:0042472
GeneOntologyBiologicalProcessnegative regulation of organic acid transport

HTR1A HTR1B GRM7

6.03e-04321073GO:0032891
GeneOntologyBiologicalProcessneurotrophin TRK receptor signaling pathway

ZFYVE27 LMTK2 SORT1

7.23e-04341073GO:0048011
GeneOntologyBiologicalProcessaminophospholipid transport

ATP8A2 ATP8A1

9.37e-0491072GO:0015917
GeneOntologyBiologicalProcessL-serine transport

SFXN1 SFXN3

9.37e-0491072GO:0015825
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

ATP7B SLC6A15 GALR2 AMIGO1 ITPR1 ITPR2 SLC6A8 SLC9A3 KCNT2 SLC12A4 CD63 NIPA1 HTT

9.71e-0492210713GO:0098662
GeneOntologyBiologicalProcessadenylate cyclase-inhibiting G protein-coupled receptor signaling pathway

HTR1A HTR1B HTR1D GRM7

1.05e-03861074GO:0007193
GeneOntologyBiologicalProcessresponse to fructose

SREBF1 SLC2A5

1.17e-03101072GO:0009750
GeneOntologyBiologicalProcessphenylpropanoid metabolic process

UGT1A10 UGT1A9

1.17e-03101072GO:0009698
GeneOntologyBiologicalProcesscoumarin metabolic process

UGT1A10 UGT1A9

1.17e-03101072GO:0009804
GeneOntologyBiologicalProcessL-leucine transport

SLC6A15 SLC7A6

1.17e-03101072GO:0015820
GeneOntologyBiologicalProcesscholine transport

SLC44A2 SLC44A4

1.17e-03101072GO:0015871
GeneOntologyCellularComponentsecretory granule membrane

DSC1 SLC44A2 SYT2 SLC2A5 ITPR1 ITPR2 FAM170B CMTM6 ATP8A1 CD63 SYT5

1.10e-0632910811GO:0030667
GeneOntologyCellularComponentcytoplasmic vesicle membrane

ZFYVE27 DSC1 ATP8A2 SREBF1 SLC44A2 SYT2 TLR8 SLC2A5 ITPR1 ITPR2 SORT1 FAM170B CMTM6 SLC9A3 ATP8A1 SYT8 LRP2 CD63 SYT5 ATM HTT

2.90e-06130710821GO:0030659
GeneOntologyCellularComponentvesicle membrane

ZFYVE27 DSC1 ATP8A2 SREBF1 SLC44A2 SYT2 TLR8 SLC2A5 ITPR1 ITPR2 SORT1 FAM170B CMTM6 SLC9A3 ATP8A1 SYT8 LRP2 CD63 SYT5 ATM HTT

3.60e-06132510821GO:0012506
GeneOntologyCellularComponentphospholipid-translocating ATPase complex

ATP8A2 ATP8B2 ATP8A1

4.68e-05141083GO:1990531
GeneOntologyCellularComponenttransport vesicle

SREBF1 CACFD1 SYT2 ITPR1 SORT1 SSPN NRSN2 ATP8A1 SYT8 SYT5 ATM

7.83e-0551910811GO:0030133
GeneOntologyCellularComponentendosome

GAPVD1 ZFYVE27 ATP7B ATP8A2 LMTK2 CACFD1 WDFY4 PANK1 TLR8 SORT1 CMTM6 SLC9A3 LRP2 CD63 SYT5 NIPA1 HTT

9.84e-05116710817GO:0005768
GeneOntologyCellularComponentrecycling endosome

ZFYVE27 LMTK2 CACFD1 PANK1 CMTM6 SLC9A3 SYT5

1.56e-042221087GO:0055037
GeneOntologyCellularComponentdense core granule

HTR1D SYT2 SYT8 SYT5

2.01e-04561084GO:0031045
GeneOntologyCellularComponentendoplasmic reticulum membrane

RNF186 ZFYVE27 UGT1A10 SREBF1 UGT2A2 UGT1A9 CACFD1 ATP8B2 TLR8 ITPR1 ITPR2 SORT1 ERGIC1 ALG9 UGT2A1 PIGW HSD17B3

3.32e-04129310817GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

RNF186 ZFYVE27 UGT1A10 SREBF1 UGT2A2 UGT1A9 CACFD1 ATP8B2 TLR8 ITPR1 ITPR2 SORT1 ERGIC1 ALG9 UGT2A1 PIGW HSD17B3

3.51e-04129910817GO:0098827
GeneOntologyCellularComponentplatelet dense granule membrane

ITPR1 CD63

3.91e-0461082GO:0031088
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

RNF186 ZFYVE27 UGT1A10 SREBF1 UGT2A2 UGT1A9 CACFD1 ATP8B2 TLR8 ITPR1 ITPR2 SORT1 ERGIC1 ALG9 UGT2A1 PIGW HSD17B3

4.48e-04132710817GO:0042175
GeneOntologyCellularComponentaxon

HTR1A HTR1B ZFYVE27 LMTK2 ADGRL1 SYT2 GRM7 AMIGO1 ITPR2 SYT8 LRP2 SYT5 HTT

6.85e-0489110813GO:0030424
GeneOntologyCellularComponenttransport vesicle membrane

SREBF1 SYT2 ITPR1 ATP8A1 SYT8 SYT5 ATM

8.26e-042931087GO:0030658
GeneOntologyCellularComponentreceptor complex

HTR1B TSHR ADGRV1 GRM7 LRP1B ITPR2 TGFBR2 TRBV19 TAS1R2 LRP2

8.59e-0458110810GO:0043235
GeneOntologyCellularComponentchromaffin granule membrane

SYT2 ATP8A1

9.30e-0491082GO:0042584
GeneOntologyCellularComponentplatelet dense tubular network membrane

ITPR1 ITPR2

9.30e-0491082GO:0031095
GeneOntologyCellularComponentspecific granule membrane

SLC44A2 SLC2A5 CMTM6 ATP8A1

1.28e-03911084GO:0035579
GeneOntologyCellularComponentplatelet dense tubular network

ITPR1 ITPR2

1.41e-03111082GO:0031094
GeneOntologyCellularComponentsecretory vesicle

HTR1D DSC1 SLC44A2 CACFD1 SYT2 SLC2A5 ITPR1 ITPR2 FAM170B CMTM6 ATP8A1 SYT8 CD63 SYT5 ATM

1.85e-03124610815GO:0099503
GeneOntologyCellularComponentpresynapse

HTR1A HTR1B ADGRL1 CACFD1 SYT2 GRM7 ITPR1 ATP8A1 SYT8 SYT5 ATM HTT

2.08e-0388610812GO:0098793
GeneOntologyCellularComponentsecretory granule

HTR1D DSC1 SLC44A2 SYT2 SLC2A5 ITPR1 ITPR2 FAM170B CMTM6 ATP8A1 SYT8 CD63 SYT5

2.20e-03101410813GO:0030141
GeneOntologyCellularComponentexocytic vesicle membrane

SYT2 ATP8A1 SYT8 SYT5 ATM

2.38e-031791085GO:0099501
GeneOntologyCellularComponentsynaptic vesicle membrane

SYT2 ATP8A1 SYT8 SYT5 ATM

2.38e-031791085GO:0030672
GeneOntologyCellularComponentchromaffin granule

SYT2 ATP8A1

2.66e-03151082GO:0042583
GeneOntologyCellularComponentcoated vesicle

SREBF1 SYT2 PANK1 SORT1 ERGIC1 LRP2 HTT

2.67e-033601087GO:0030135
GeneOntologyCellularComponentrecycling endosome membrane

ZFYVE27 CMTM6 SLC9A3 SYT5

2.73e-031121084GO:0055038
GeneOntologyCellularComponentlysosomal membrane

SLC44A2 TLR8 SORT1 CMTM6 ATP8A1 SLC12A4 LRP2 CD63

2.75e-034621088GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

SLC44A2 TLR8 SORT1 CMTM6 ATP8A1 SLC12A4 LRP2 CD63

2.75e-034621088GO:0098852
GeneOntologyCellularComponentsynaptic membrane

HTR1A HTR1B ADGRL1 GRM7 ITPR1 SLC6A8 SSPN ADGRL2 HTT

3.25e-035831089GO:0097060
GeneOntologyCellularComponentearly endosome

LMTK2 CACFD1 WDFY4 SORT1 CMTM6 SLC9A3 NIPA1 HTT

3.51e-034811088GO:0005769
GeneOntologyCellularComponentazurophil granule membrane

CMTM6 ATP8A1 CD63

3.53e-03591083GO:0035577
GeneOntologyCellularComponentsynaptic vesicle

CACFD1 SYT2 ATP8A1 SYT8 SYT5 ATM

4.68e-033001086GO:0008021
GeneOntologyCellularComponentvacuolar membrane

SLC44A2 TLR8 SORT1 CMTM6 ATP8A1 SLC12A4 LRP2 CD63

4.81e-035071088GO:0005774
GeneOntologyCellularComponentplatelet dense granule

ITPR1 CD63

5.21e-03211082GO:0042827
GeneOntologyCellularComponentexocytic vesicle

CACFD1 SYT2 ATP8A1 SYT8 SYT5 ATM

6.37e-033201086GO:0070382
Domain5HT_rcpt

HTR1A HTR1B HTR1D

1.42e-0591053IPR002231
Domain-

ATP7B ATP8A2 ATP8B2 ATP8A1

3.00e-053210543.40.1110.10
Domain-

ATP7B ATP8A2 ATP8B2 ATP8A1

3.00e-053210542.70.150.10
DomainMDFI

MDFIC MDFI

3.13e-0521052PF15316
DomainMDFI/MDFIC

MDFIC MDFI

3.13e-0521052IPR026134
DomainATPase_P-typ_cyto_domN

ATP7B ATP8A2 ATP8B2 ATP8A1

4.32e-05351054IPR023299
DomainP_typ_ATPase

ATP7B ATP8A2 ATP8B2 ATP8A1

4.84e-05361054IPR001757
DomainATPase_P-typ_P_site

ATP7B ATP8A2 ATP8B2 ATP8A1

4.84e-05361054IPR018303
DomainATPASE_E1_E2

ATP7B ATP8A2 ATP8B2 ATP8A1

4.84e-05361054PS00154
DomainATPase_P-typ_transduc_dom_A

ATP7B ATP8A2 ATP8B2 ATP8A1

5.40e-05371054IPR008250
DomainE1-E2_ATPase

ATP7B ATP8A2 ATP8B2 ATP8A1

5.40e-05371054PF00122
DomainP_typ_ATPase_c

ATP8A2 ATP8B2 ATP8A1

6.01e-05141053IPR032630
DomainP-type_ATPase_N

ATP8A2 ATP8B2 ATP8A1

6.01e-05141053IPR032631
DomainP-type_ATPase_IV

ATP8A2 ATP8B2 ATP8A1

6.01e-05141053IPR006539
DomainPhoLip_ATPase_C

ATP8A2 ATP8B2 ATP8A1

6.01e-05141053PF16212
DomainPhoLip_ATPase_N

ATP8A2 ATP8B2 ATP8A1

6.01e-05141053PF16209
DomainInsP3_rcpt-bd

ITPR1 ITPR2

9.36e-0531052IPR000493
DomainGalanin_rcpt

GALR3 GALR2

9.36e-0531052IPR000405
DomainLatrophilin

ADGRL1 ADGRL2

9.36e-0531052PF02354
DomainGPCR_2_latrophilin_rcpt_C

ADGRL1 ADGRL2

9.36e-0531052IPR003334
DomainSynaptotagmin

SYT2 SYT8 SYT5

1.84e-04201053IPR001565
DomainUDPGT

UGT1A10 UGT1A9 UGT2A1

2.13e-04211053PF00201
DomainUDPGT

UGT1A10 UGT1A9 UGT2A1

2.13e-04211053PS00375
DomainUDP_glucos_trans

UGT1A10 UGT1A9 UGT2A1

2.13e-04211053IPR002213
DomainGPCR_2_latrophilin

ADGRL1 ADGRL2

3.10e-0451052IPR003924
DomainMtc

SFXN1 SFXN3

3.10e-0451052PF03820
DomainLectin_gal-bd_dom

ADGRL1 ADGRL2

3.10e-0451052IPR000922
DomainGal_Lectin

ADGRL1 ADGRL2

3.10e-0451052PF02140
DomainCholine_transpo

SLC44A2 SLC44A4

3.10e-0451052PF04515
DomainSUEL_LECTIN

ADGRL1 ADGRL2

3.10e-0451052PS50228
DomainMtc

SFXN1 SFXN3

3.10e-0451052IPR004686
DomainCholine_transptr-like

SLC44A2 SLC44A4

3.10e-0451052IPR007603
Domain7tm_1

HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 TSHR GALR2 GNRHR2 OR51Q1 LPAR6 GPR132

4.18e-0467710512PF00001
Domain7TM_GPCR_Srsx

HTR1A HTR1B HTR1D LPAR4 GALR2

4.25e-041121055SM01381
Domain-

ATP7B ATP8A2 ATP8B2 ATP8A1

4.62e-046410543.40.50.1000
DomainRIH_assoc

ITPR1 ITPR2

4.63e-0461052PF08454
DomainRIH_assoc-dom

ITPR1 ITPR2

4.63e-0461052IPR013662
DomainRIH_dom

ITPR1 ITPR2

4.63e-0461052IPR000699
DomainIns145_P3_rcpt

ITPR1 ITPR2

4.63e-0461052IPR014821
DomainRyanodine_recept-rel

ITPR1 ITPR2

4.63e-0461052IPR015925
Domain-

ITPR1 ITPR2

4.63e-04610521.25.10.30
DomainRYDR_ITPR

ITPR1 ITPR2

4.63e-0461052PF01365
DomainIns145_P3_rec

ITPR1 ITPR2

4.63e-0461052PF08709
DomainG_PROTEIN_RECEP_F1_1

HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 TSHR GALR2 GNRHR2 OR51Q1 LPAR6 GPR132

4.65e-0468510512PS00237
DomainG_PROTEIN_RECEP_F1_2

HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 TSHR GALR2 GNRHR2 OR51Q1 LPAR6 GPR132

5.02e-0469110512PS50262
DomainGPCR_Rhodpsn

HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 TSHR GALR2 GNRHR2 OR51Q1 LPAR6 GPR132

5.09e-0469210512IPR000276
DomainGPS

ADGRL1 ADGRV1 ADGRL2

9.10e-04341053SM00303
DomainGPS

ADGRL1 ADGRV1 ADGRL2

9.91e-04351053PF01825
DomainHAD-like_dom

ATP7B ATP8A2 ATP8B2 ATP8A1

1.03e-03791054IPR023214
DomainGPS

ADGRL1 ADGRV1 ADGRL2

1.08e-03361053PS50221
DomainPtc/Disp

PTCHD1 PTCH2

1.10e-0391052IPR003392
DomainPatched

PTCHD1 PTCH2

1.10e-0391052PF02460
DomainGPS

ADGRL1 ADGRV1 ADGRL2

1.17e-03371053IPR000203
DomainGPCR_Rhodpsn_7TM

HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 TSHR GALR2 OR51Q1 LPAR6 GPR132

1.37e-0367010511IPR017452
DomainMIR

ITPR1 ITPR2

1.37e-03101052PS50919
DomainMIR

ITPR1 ITPR2

1.37e-03101052PF02815
DomainMIR

ITPR1 ITPR2

1.37e-03101052SM00472
DomainMIR_motif

ITPR1 ITPR2

1.37e-03101052IPR016093
DomainG_PROTEIN_RECEP_F2_1

ADGRL1 ADGRV1 ADGRL2

1.47e-03401053PS00649
DomainGPCR_2_extracellular_dom

ADGRL1 ADGRV1 ADGRL2

1.47e-03401053IPR001879
DomainG_PROTEIN_RECEP_F2_3

ADGRL1 ADGRV1 ADGRL2

1.47e-03401053PS50227
DomainGAIN_dom_N

ADGRL1 ADGRL2

1.67e-03111052IPR032471
DomainGAIN

ADGRL1 ADGRL2

1.67e-03111052PF16489
DomainNCD3G

GRM7 TAS1R2

2.35e-03131052PF07562
DomainOLF

ADGRL1 ADGRL2

2.35e-03131052PS51132
DomainGPCR_3_9-Cys_dom

GRM7 TAS1R2

2.35e-03131052IPR011500
DomainSSD

PTCHD1 PTCH2

2.35e-03131052IPR000731
DomainSSD

PTCHD1 PTCH2

2.35e-03131052PS50156
DomainOlfac-like_dom

ADGRL1 ADGRL2

2.35e-03131052IPR003112
DomainOLF

ADGRL1 ADGRL2

2.35e-03131052SM00284
DomainOLF

ADGRL1 ADGRL2

2.35e-03131052PF02191
DomainLdl_recept_b

LRP1B LRP2

2.73e-03141052PF00058
DomainLDLRB

LRP1B LRP2

2.73e-03141052PS51120
DomainGPCR_3_CS

GRM7 TAS1R2

2.73e-03141052IPR017979
DomainG_PROTEIN_RECEP_F2_2

ADGRL1 ADGRV1 ADGRL2

2.79e-03501053PS00650
Domain7tm_2

ADGRL1 ADGRV1 ADGRL2

2.79e-03501053PF00002
DomainARM-type_fold

USP34 HEATR5A WDFY4 ITPR1 ITPR2 ATM HTT

3.04e-033391057IPR016024
DomainLY

LRP1B LRP2

3.13e-03151052SM00135
DomainLDLR_classB_rpt

LRP1B LRP2

3.13e-03151052IPR000033
DomainNA_NEUROTRAN_SYMP_2

SLC6A15 SLC6A8

4.52e-03181052PS00754
DomainGPCR_2_secretin-like

ADGRL1 ADGRV1 ADGRL2

4.68e-03601053IPR000832
DomainGPCR_2-like

ADGRL1 ADGRV1 ADGRL2

4.68e-03601053IPR017981
DomainG_PROTEIN_RECEP_F2_4

ADGRL1 ADGRV1 ADGRL2

4.91e-03611053PS50261
DomainSNF

SLC6A15 SLC6A8

5.03e-03191052PF00209
DomainNA_NEUROTRAN_SYMP_1

SLC6A15 SLC6A8

5.03e-03191052PS00610
DomainNA_NEUROTRAN_SYMP_3

SLC6A15 SLC6A8

5.03e-03191052PS50267
DomainNa/ntran_symport

SLC6A15 SLC6A8

5.03e-03191052IPR000175
PathwayWP_GPCRS_NONODORANT

HTR1A HTR1B HTR1D LPAR4 ADGRL1 TSHR GRM7 GALR2 LPAR6 ADGRL2 GPR132

2.55e-072667911MM15843
PathwayREACTOME_ASPIRIN_ADME

GLYAT UGT1A10 UGT2A2 UGT1A9 UGT2A1

4.98e-0645795MM15694
PathwayREACTOME_SIGNALING_BY_GPCR

HTR1A HTR1B HTR1D LPAR4 GALR3 TSHR GRM7 GALR2 ADCY3 ITPR1 ITPR2 LPAR6 TAS1R2 PTCH2 GPR132

6.80e-067027915M746
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT2A2 UGT1A9 UGT2A1

8.91e-0624794MM14599
PathwayREACTOME_GPCR_LIGAND_BINDING

HTR1A HTR1B HTR1D LPAR4 GALR3 TSHR GRM7 GALR2 LPAR6 TAS1R2 PTCH2 GPR132

9.49e-064637912M507
PathwayREACTOME_GLUCURONIDATION

UGT1A10 UGT2A2 UGT1A9 UGT2A1

1.06e-0525794M17787
PathwayWP_GLUCURONIDATION

UGT1A10 UGT2A2 UGT1A9 UGT2A1

1.06e-0525794MM15820
PathwayREACTOME_SIGNALING_BY_GPCR

HTR1A HTR1B HTR1D LPAR4 GALR3 TSHR GRM7 GALR2 ADCY3 ITPR1 ITPR2 LPAR6 TAS1R2 GPR132

1.23e-056467914MM14962
PathwayWP_GLUCURONIDATION

UGT1A10 UGT2A2 UGT1A9 UGT2A1

1.24e-0526794M39404
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

HTR1A HTR1B HTR1D LPAR4 GALR3 TSHR GRM7 GALR2 LPAR6

2.05e-05272799M13380
PathwayREACTOME_GPCR_LIGAND_BINDING

HTR1A HTR1B HTR1D LPAR4 GALR3 TSHR GRM7 GALR2 LPAR6 TAS1R2 GPR132

2.61e-054307911MM15160
PathwayREACTOME_SEROTONIN_RECEPTORS

HTR1A HTR1B HTR1D

2.71e-0511793MM15008
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

GLYAT UGT1A10 UGT2A2 UGT1A9 UGT2A1 MTRR

2.95e-05107796MM14595
PathwayREACTOME_PHASE_II_CONJUGATION_OF_COMPOUNDS

GLYAT UGT1A10 UGT2A2 UGT1A9 UGT2A1 MTRR

3.27e-05109796M18788
PathwayREACTOME_SEROTONIN_RECEPTORS

HTR1A HTR1B HTR1D

3.59e-0512793M6034
PathwayWP_SEROTONIN_HTR1_GROUP_AND_FOS_PATHWAY

HTR1A HTR1B HTR1D ITPR1

5.24e-0537794M42558
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

HTR1B HTR1D GALR3 GRM7 GALR2 ADCY3 ITPR1 ITPR2 TAS1R2

6.30e-05314799M600
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

HTR1A HTR1B HTR1D LPAR4 GALR3 TSHR GALR2 LPAR6 GPR132

9.23e-05330799M18334
PathwayREACTOME_CLASS_A_1_RHODOPSIN_LIKE_RECEPTORS

HTR1A HTR1B HTR1D LPAR4 GALR3 TSHR GALR2 LPAR6 GPR132

9.88e-05333799MM14963
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

HTR1A HTR1B HTR1D LPAR4 GALR3 GPR85 GALR2 LPAR6

1.01e-04260798M39397
PathwayREACTOME_ASPIRIN_ADME

GLYAT UGT2A2 UGT1A9 UGT2A1

1.05e-0444794M45014
PathwayKEGG_STEROID_HORMONE_BIOSYNTHESIS

UGT1A10 UGT1A9 UGT2A1 HSD17B3

2.51e-0455794M14933
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP7B ATP8A2 ATP8B2 ATP8A1

2.51e-0455794M971
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2 HTT

2.77e-0423793M47676
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP7B ATP8A2 ATP8B2 ATP8A1

2.88e-0457794MM15643
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKN_TO_MGLUR1_SIGNALING_PATHWAY

ITPR1 ITPR2

3.07e-045792M49000
PathwayWP_ESTROGEN_METABOLISM_WP5276

UGT1A10 UGT2A2 HSD17B3

3.15e-0424793M46445
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

UGT1A10 UGT1A9 UGT2A1

3.56e-0425793M605
PathwayREACTOME_DRUG_ADME

GLYAT UGT1A10 UGT2A2 UGT1A9 UGT2A1

3.61e-04109795M45012
PathwayKEGG_MEDICUS_REFERENCE_CA2_PLCD_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2

4.58e-046792M47960
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT1A10 UGT1A9 UGT2A1

5.02e-0428793M19580
PathwayREACTOME_DRUG_ADME

GLYAT UGT1A10 UGT2A2 UGT1A9 UGT2A1

5.40e-04119795MM15692
PathwayWP_GPCRS_CLASS_A_RHODOPSINLIKE

HTR1A HTR1B HTR1D GALR3 TSHR GALR2

6.09e-04186796MM15994
PathwayWP_MONOAMINE_GPCRS

HTR1A HTR1B HTR1D

6.80e-0431793MM15871
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP7B ATP8A2 SLC44A2 SLC6A15 SLC44A4 SLC7A6 ADCY3 ATP8B2 SLC9A3 ATP8A1 SLC12A4 NIPA1

7.66e-047367912M27287
PathwayWP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY

ITPR1 ITPR2 TGFBR2 SSPN

7.81e-0474794M48080
PathwayWP_MONOAMINE_GPCRS

HTR1A HTR1B HTR1D

8.19e-0433793M39585
PathwayWP_PEPTIDE_GPCRS

GALR3 TSHR GALR2 ATP8A1

8.21e-0475794M39696
PathwayKEGG_MEDICUS_REFERENCE_HEDGEHOG_SIGNALING_PATHWAY_PTCH_CORECEPTOR

PTCH2 LRP2

1.09e-039792M47893
PathwayKEGG_MEDICUS_REFERENCE_BCR_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2

1.09e-039792M47852
PathwayWP_NRF2_PATHWAY

UGT1A9 SLC6A15 SLC2A5 SLC6A8 TGFBR2

1.16e-03141795M39454
PathwayREACTOME_G_ALPHA_I_SIGNALLING_EVENTS

HTR1B HTR1D GALR3 GRM7 GALR2 ADCY3 TAS1R2

1.16e-03289797MM15057
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_SPTBN2_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

1.36e-0310792M47661
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP7B ATP8A2 SLC44A2 SLC6A15 SLC44A4 SLC7A6 ATP8B2 SLC9A3 ATP8A1 SLC12A4 NIPA1

1.39e-036817911MM14985
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

GLYAT UGT1A10 UGT2A2 UGT1A9 UGT2A1 MTRR

1.42e-03219796MM14838
PathwayREACTOME_BIOLOGICAL_OXIDATIONS

GLYAT UGT1A10 UGT2A2 UGT1A9 UGT2A1 MTRR

1.45e-03220796M10320
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT1A10 UGT1A9 UGT2A1

1.55e-0341793M7399
PathwayREACTOME_DAG_AND_IP3_SIGNALING

ADCY3 ITPR1 ITPR2

1.55e-0341793M512
PathwayREACTOME_P2Y_RECEPTORS

LPAR4 LPAR6

1.65e-0311792MM15049
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKCG_TO_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

1.65e-0311792M49033
PathwayWP_NUCLEOTIDE_GPCRS

LPAR4 LPAR6

1.65e-0311792M39422
PathwayREACTOME_CLEC7A_DECTIN_1_INDUCES_NFAT_ACTIVATION

ITPR1 ITPR2

1.65e-0311792M27466
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

HTR1A HTR1B HTR1D

1.66e-0342793M5868
PathwayREACTOME_AMINE_LIGAND_BINDING_RECEPTORS

HTR1A HTR1B HTR1D

1.66e-0342793MM14971
PathwayREACTOME_P2Y_RECEPTORS

LPAR4 LPAR6

1.97e-0312792M10960
PathwayWP_NUCLEOTIDE_GPCRS

LPAR4 LPAR6

1.97e-0312792MM15953
PathwayWP_IRINOTECAN_PATHWAY

UGT1A10 UGT1A9

1.97e-0312792M39611
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC44A2 SLC6A15 SLC44A4 SLC7A6 SLC9A3 SLC12A4

2.16e-03238796MM15076
PathwayKEGG_MEDICUS_REFERENCE_MGLUR1_TRPC3_SIGNALING_PATHWAY

ITPR1 ITPR2

2.32e-0313792M47656
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_PSEN1_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

2.32e-0313792M47696
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_SIGMAR1_TO_CA2_APOPTOTIC_PATHWAY

ITPR1 ITPR2

2.32e-0313792M47751
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2

2.32e-0313792MM14553
PathwayWP_CODEINE_AND_MORPHINE_METABOLISM

UGT1A10 UGT1A9

2.70e-0314792M39328
PathwayREACTOME_SLC_MEDIATED_TRANSMEMBRANE_TRANSPORT

SLC44A2 SLC6A15 SLC44A4 SLC7A6 SLC9A3 SLC12A4

2.71e-03249796M5988
PathwayKEGG_DRUG_METABOLISM_OTHER_ENZYMES

UGT1A10 UGT1A9 UGT2A1

2.91e-0351793M17726
PathwayKEGG_STARCH_AND_SUCROSE_METABOLISM

UGT1A10 UGT1A9 UGT2A1

3.07e-0352793M14171
PathwayPID_LPA4_PATHWAY

LPAR4 ADCY3

3.11e-0315792M56
PathwayREACTOME_COBALAMIN_CBL_VITAMIN_B12_TRANSPORT_AND_METABOLISM

LRP2 MTRR

3.11e-0315792MM14762
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A15 SLC7A6 SLC9A3 SLC12A4

3.15e-03108794M823
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

ADCY3 ITPR1 ITPR2 SYT5

3.15e-03108794M17034
PathwayREACTOME_TRANSPORT_OF_INORGANIC_CATIONS_ANIONS_AND_AMINO_ACIDS_OLIGOPEPTIDES

SLC6A15 SLC7A6 SLC9A3 SLC12A4

3.26e-03109794MM15074
PathwayREACTOME_G_PROTEIN_MEDIATED_EVENTS

ADCY3 ITPR1 ITPR2

3.42e-0354793M26911
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

LPAR4 LPAR6

3.54e-0316792MM15050
PathwayREACTOME_ELEVATION_OF_CYTOSOLIC_CA2_LEVELS

ITPR1 ITPR2

3.54e-0316792M26945
PathwayREACTOME_NUCLEOTIDE_LIKE_PURINERGIC_RECEPTORS

LPAR4 LPAR6

3.54e-0316792M6786
PathwayKEGG_MEDICUS_REFERENCE_RTK_PLCG_ITPR_SIGNALING_PATHWAY

ITPR1 ITPR2 FGF10

3.60e-0355793M47952
PathwayWP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II

GLYAT UGT1A10 UGT2A2 UGT1A9 UGT2A1

3.62e-03183795M39588
Pubmed

Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins.

TSHR ADGRV1 GRM7 LRP1B ITPR2 TAS1R2 LRP2

3.09e-08101108723382219
Pubmed

Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development.

HTR1A HTR1B HTR1D

1.16e-074108316824687
Pubmed

Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases.

ATP8A2 ATP8B2 ATP8A1

1.01e-067108320947505
Pubmed

Dissociation of heterotrimeric g proteins in cells.

HTR1A HTR1B HTR1D GALR3 GALR2 GNRHR2 LPAR6

1.53e-06179108718577758
Pubmed

Oligomerization of G-protein-coupled receptors shown by selective co-immunoprecipitation.

HTR1A HTR1B HTR1D

1.61e-068108311854302
Pubmed

Comprehensive copy number variant (CNV) analysis of neuronal pathways genes in psychiatric disorders identifies rare variants within patients.

HTR1B GALR3 GRM7 GNRHR2 NIPA1

2.18e-0667108520398908
Pubmed

Reviews in molecular biology and biotechnology: transmembrane signaling by G protein-coupled receptors.

HTR1A HTR1B HTR1D LPAR4 TSHR GNRHR2 LPAR6

3.20e-06200108718240029
Pubmed

The type 4 subfamily of P-type ATPases, putative aminophospholipid translocases with a role in human disease.

ATP8A2 ATP8B2 ATP8A1

3.44e-0610108315919184
Pubmed

Serotonin genes and gene-gene interactions in borderline personality disorder in a matched case-control study.

HTR1A HTR1B HTR1D

3.44e-0610108319032968
Pubmed

Variants of dopamine and serotonin candidate genes as predictors of response to risperidone treatment in first-episode schizophrenia.

HTR1A HTR1B HTR1D

4.72e-0611108318855532
Pubmed

SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms.

SYT2 SYT8 SYT5

4.72e-0611108310734137
Pubmed

Differential expression of putative transbilayer amphipath transporters.

ATP8A2 ATP8B2 ATP8A1

8.14e-0613108311015572
Pubmed

UGT1A1 is a major locus influencing bilirubin levels in African Americans.

UGT1A10 UGT1A9 ADGRL2

8.14e-0613108322085899
Pubmed

Maternal effects in infant and adult phenotypes of 5HT1A and 5HT1B receptor knockout mice.

HTR1A HTR1B

9.55e-062108212555283
Pubmed

Effects of galanin receptor 2 and receptor 3 knockout in mouse models of acute seizures.

GALR3 GALR2

9.55e-062108230298565
Pubmed

The phe-124-Cys and A-161T variants of the human 5-HT1B receptor gene are not major determinants of the clinical response to sumatriptan.

HTR1B HTR1D

9.55e-062108217501853
Pubmed

Mouse 5HT1B serotonin receptor: cloning, functional expression, and localization in motor control centers.

HTR1B HTR1D

9.55e-06210821557407
Pubmed

Molecular cloning of a human serotonin receptor (S12) with a pharmacological profile resembling that of the 5-HT1D subtype.

HTR1A HTR1B

9.55e-06210821559993
Pubmed

Targeting ATM ameliorates mutant Huntingtin toxicity in cell and animal models of Huntington's disease.

ATM HTT

9.55e-062108225540325
Pubmed

Serotonin receptor 1A knockout: an animal model of anxiety-related disorder.

HTR1A HTR1B

9.55e-06210829826725
Pubmed

Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.

HTR1B HTR1D

9.55e-062108225170871
Pubmed

Primary structure and functional characterization of a human 5-HT1D-type serotonin receptor.

HTR1B HTR1D

9.55e-06210821652050
Pubmed

Functional polymorphisms of the 5-HT1A and 5-HT1B receptor are associated with clinical symptoms in migraineurs.

HTR1A HTR1B

9.55e-062108217417740
Pubmed

Immunolocalization of type 2 inositol 1,4,5-trisphosphate receptors in cardiac myocytes from newborn mice.

ITPR1 ITPR2

9.55e-062108215201137
Pubmed

Sulphide signalling potentiates apoptosis through the up-regulation of IP3 receptor types 1 and 2.

ITPR1 ITPR2

9.55e-062108223582047
Pubmed

Characterization of 5-HT(1A/1B)-/- mice: an animal model sensitive to anxiolytic treatments.

HTR1A HTR1B

9.55e-062108221333660
Pubmed

Decreased G-protein coupling of serotonin 5-HT(1A) receptors in the brain of 5-HT(1B) knockout mouse.

HTR1A HTR1B

9.55e-062108212069904
Pubmed

Genetic association of 5-HT1A and 5-HT1B gene polymorphisms with migraine in a Turkish population.

HTR1A HTR1B

9.55e-062108223375453
Pubmed

Down-regulation of 5-HT1B and 5-HT1D receptors inhibits proliferation, clonogenicity and invasion of human pancreatic cancer cells.

HTR1B HTR1D

9.55e-062108225268648
Pubmed

Knockout mice reveal opposite roles for serotonin 1A and 1B receptors in prepulse inhibition.

HTR1A HTR1B

9.55e-062108210788764
Pubmed

Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.

ATM HTT

9.55e-062108228017939
Pubmed

Serotonin receptor knockouts: a moody subject.

HTR1A HTR1B

9.55e-06210829860934
Pubmed

Molecular cloning and functional characterization of a human 5-HT1B serotonin receptor: a homologue of the rat 5-HT1B receptor with 5-HT1D-like pharmacological specificity.

HTR1B HTR1D

9.55e-06210821315531
Pubmed

Type 1 and 2 IP3 receptors respond differently to catecholamines and stress.

ITPR1 ITPR2

9.55e-062108219120126
Pubmed

The HTR1A and HTR1B receptor genes influence stress-related information processing.

HTR1A HTR1B

9.55e-062108220638825
Pubmed

Specific association of megalin and the Na+/H+ exchanger isoform NHE3 in the proximal tubule.

SLC9A3 LRP2

9.55e-062108210364184
Pubmed

Altered serotonin and dopamine metabolism in the CNS of serotonin 5-HT(1A) or 5-HT(1B) receptor knockout mice.

HTR1A HTR1B

9.55e-062108211080193
Pubmed

Mutations of the Huntington's disease protein impact on the ATM-dependent signaling and repair pathways of the radiation-induced DNA double-strand breaks: corrective effect of statins and bisphosphonates.

ATM HTT

9.55e-062108224277524
Pubmed

5-HT1B receptor knockout, but not 5-HT1A receptor knockout mice, show reduced startle reactivity and footshock-induced sensitization, as measured with the acoustic startle response.

HTR1A HTR1B

9.55e-062108211164514
Pubmed

Galanin and its three receptors in human pituitary adenoma.

GALR3 GALR2

9.55e-062108222889491
Pubmed

Differential addressing of 5-HT1A and 5-HT1B receptors in epithelial cells and neurons.

HTR1A HTR1B

9.55e-062108210036246
Pubmed

Lack of association or linkage disequilibrium between schizophrenia and polymorphisms in the 5-HT1Dalpha and 5-HT1Dbeta autoreceptor genes: family-based association study.

HTR1A HTR1B

9.55e-062108215211620
Pubmed

Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes.

LPAR4 LPAR6

9.55e-062108226714589
Pubmed

Acute serotonin 1B/1A receptor activation impairs behavioral flexibility in C57BL/6J mice.

HTR1A HTR1B

9.55e-062108235367298
Pubmed

[Association study of HTR1A and HTR1B with adolescent idiopathic scoliosis].

HTR1A HTR1B

9.55e-062108220388441
Pubmed

SSRI response in depression may be influenced by SNPs in HTR1B and HTR1A.

HTR1A HTR1B

9.55e-062108219829169
Pubmed

Differences in the glucuronidation of bisphenols F and S between two homologous human UGT enzymes, 1A9 and 1A10.

UGT1A10 UGT1A9

9.55e-062108225547628
Pubmed

Operant learning and differential-reinforcement-of-low-rate 36-s responding in 5-HT1A and 5-HT1B receptor knockout mice.

HTR1A HTR1B

9.55e-062108212742250
Pubmed

Thyrotropin increases hepatic triglyceride content through upregulation of SREBP-1c activity.

SREBF1 TSHR

9.55e-062108225016220
Pubmed

Ubiquitin-specific protease 34 in macrophages limits CD8 T cell-mediated onset of vitiligo in mice.

USP34 ATM

9.55e-062108237043976
Pubmed

Sucrose intake and fasting glucose levels in 5-HT(1A) and 5-HT(1B) receptor mutant mice.

HTR1A HTR1B

9.55e-062108218155098
Pubmed

Involvement of Neuropeptide Galanin Receptors 2 and 3 in Learning, Memory and Anxiety in Aging Mice.

GALR3 GALR2

9.55e-062108233915732
Pubmed

An antidepressant behaviour in mice carrying a gene-specific InsP3R1, InsP3R2 and InsP3R3 protein knockdown.

ITPR1 ITPR2

9.55e-062108218708078
Pubmed

Regional patterns of compensation following genetic deletion of either 5-hydroxytryptamine(1A) or 5-hydroxytryptamine(1B) receptor in the mouse.

HTR1A HTR1B

9.55e-062108211504806
Pubmed

Genetic regulation of extracellular serotonin by 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) autoreceptors in different brain regions of the mouse.

HTR1A HTR1B

9.55e-062108211504805
Pubmed

Antidepressant-like behavioral effects in 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(1B) receptor mutant mice.

HTR1A HTR1B

9.55e-062108211504807
Pubmed

Human serotonin 1D receptor is encoded by a subfamily of two distinct genes: 5-HT1D alpha and 5-HT1D beta.

HTR1B HTR1D

9.55e-06210821565658
Pubmed

HTR1A/1B DNA methylation may predict escitalopram treatment response in depressed Chinese Han patients.

HTR1A HTR1B

9.55e-062108229275155
Pubmed

Regional changes in density of serotonin transporter in the brain of 5-HT1A and 5-HT1B knockout mice, and of serotonin innervation in the 5-HT1B knockout.

HTR1A HTR1B

9.55e-062108211483665
Pubmed

Identification of UDP-glucuronosyltransferases responsible for the glucuronidation of darexaban, an oral factor Xa inhibitor, in human liver and intestine.

UGT1A10 UGT1A9

9.55e-062108222031623
Pubmed

Elevated expression of galanin receptors in childhood neuroblastic tumors.

GALR3 GALR2

9.55e-062108211867941
Pubmed

The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste.

UGT2A2 UGT2A1

9.55e-062108235039640
Pubmed

Lysophosphatidic Acid Receptor 4 Activation Augments Drug Delivery in Tumors by Tightening Endothelial Cell-Cell Contact.

LPAR4 LPAR6

9.55e-062108228854359
Pubmed

Rat olfactory bulb and epithelium UDP-glucuronosyltransferase 2A1 (UGT2A1) expression: in situ mRNA localization and quantitative analysis.

UGT2A2 UGT2A1

9.55e-062108211376859
Pubmed

Reappraisal of the serotonin 5-HT(1B) receptor gene in alcoholism: of mice and men.

HTR1A HTR1B

9.55e-062108211827742
Pubmed

Galanin receptor 3 attenuates inflammation and influences the gut microbiota in an experimental murine colitis model.

GALR3 GALR2

9.55e-062108233436730
Pubmed

5-HT1A/1B receptors as targets for optimizing pigmentary responses in C57BL/6 mouse skin to stress.

HTR1A HTR1B

9.55e-062108224586946
Pubmed

How many and which amino acids are responsible for the large activity differences between the highly homologous UDP-glucuronosyltransferases (UGT) 1A9 and UGT1A10?

UGT1A10 UGT1A9

9.55e-062108220089735
Pubmed

Sex differences in the regulation of serotonergic transmission and behavior in 5-HT receptor knockout mice.

HTR1A HTR1B

9.55e-062108215688089
Pubmed

Cloning and characterization of a novel human olfactory UDP-glucuronosyltransferase.

UGT2A2 UGT2A1

9.55e-062108210359671
Pubmed

Exploring the molecular structures that confer ligand selectivity for galanin type II and III receptors.

GALR3 GALR2

9.55e-062108232231393
Pubmed

Depressive-like state sensitizes 5-HT1A and 5-HT1B auto-receptors in the dorsal raphe nucleus sub-system.

HTR1A HTR1B

9.55e-062108232360167
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

USP34 TM9SF3 SREBF1 SLC6A15 ST6GAL1 LRP1B ITPR1 ITPR2 SORT1 ERGIC1 SLC6A8 ALG9 ATM HTT

2.16e-0512011081435696571
Pubmed

Association study of the serotoninergic system in migraine in the Spanish population.

HTR1A HTR1B HTR1D

2.30e-0518108319455600
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

USP34 ATP7B TM9SF3 SLC6A15 SLC7A6 ATP8B2 SORT1 TGFBR2 NRSN2 SLC12A4 INTS2 NIPA1 ATM

2.61e-0510611081333845483
Pubmed

[Development of serotonergic neurons of dorsal raphe nuclei in mice with knockout of monoamine oxidase A and 5-HT1A and 5-HT1B autoreceptor].

HTR1A HTR1B

2.86e-053108219705758
Pubmed

Evidence that type I, II, and III inositol 1,4,5-trisphosphate receptors can occur as integral plasma membrane proteins.

ITPR1 ITPR2

2.86e-053108210874040
Pubmed

A family of heptahelical receptors with adhesion-like domains: a marriage between two super families.

ADGRL1 ADGRL2

2.86e-053108210994649
Pubmed

Abnormal distribution of inositol 1,4,5-trisphosphate receptors in human muscle can be related to altered calcium signals and gene expression in Duchenne dystrophy-derived cells.

ITPR1 ITPR2

2.86e-053108220395455
Pubmed

Inositol 1,4,5-trisphosphate receptors are autoantibody target antigens in patients with Sjögren's syndrome and other systemic rheumatic diseases.

ITPR1 ITPR2

2.86e-053108217437169
Pubmed

Sustained signalling by PTH modulates IP3 accumulation and IP3 receptors through cyclic AMP junctions.

ADCY3 ITPR1

2.86e-053108225431134
Pubmed

Adaption of the serotoninergic neuronal phenotype in the absence of 5-HT autoreceptors or the 5-HT transporter: involvement of BDNF and cAMP.

HTR1A HTR1B

2.86e-053108215009141
Pubmed

5-Hydroxytryptamine(1B/1D) and 5-hydroxytryptamine1F receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis.

HTR1B HTR1D

2.86e-053108212110114
Pubmed

Glucuronidation of psilocin and 4-hydroxyindole by the human UDP-glucuronosyltransferases.

UGT1A10 UGT1A9

2.86e-053108220007669
Pubmed

Decreased olfactory mucus secretion and nasal abnormality in mice lacking type 2 and type 3 IP3 receptors.

ITPR1 ITPR2

2.86e-053108218547250
Pubmed

Inositol 1,4,5-trisphosphate receptor gene variants are related to the risk of breast cancer in a Chinese population.

ITPR1 ITPR2

2.86e-053108236350267
Pubmed

Inositol 1,4,5-trisphosphate receptors are essential for fetal-maternal connection and embryo viability.

ITPR1 ITPR2

2.86e-053108232320395
Pubmed

The versatility and universality of calcium signalling.

ITPR1 ITPR2

2.86e-053108211413485
Pubmed

Expression of serotonin receptors in mouse oocytes and preimplantation embryos.

HTR1B HTR1D

2.86e-053108212678665
Pubmed

Using concatenated subunits to investigate the functional consequences of heterotetrameric inositol 1,4,5-trisphosphate receptors.

ITPR1 ITPR2

2.86e-053108226009177
Pubmed

Receptor-activated single channels in intact human platelets.

ITPR1 ITPR2

2.86e-05310821693919
Pubmed

Functional inositol 1,4,5-trisphosphate receptors assembled from concatenated homo- and heteromeric subunits.

ITPR1 ITPR2

2.86e-053108223955339
Pubmed

Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells.

ITPR1 ITPR2

2.86e-053108231979185
Pubmed

Tsg101 regulates PI(4,5)P2/Ca(2+) signaling for HIV-1 Gag assembly.

ITPR1 ITPR2

2.86e-053108224904548
Pubmed

[Comparative Analysis of Polymorphisms of the Serotonin Receptor Genes HTR1A, HTR2A, and HTR1B in Hadza and Datoga Males].

HTR1A HTR1B

2.86e-053108226845861
Pubmed

No association between polymorphisms in four serotonin receptor genes, serotonin transporter gene and alcohol-related suicide.

HTR1A HTR1B

2.86e-053108221169892
Pubmed

[Involvement of prefrontal serotonergic neurons in methamphetamine-induced behavioral sensitization].

HTR1A HTR1B

2.86e-053108218516987
Pubmed

Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import.

SREBF1 HTT

2.86e-053108231875875
Pubmed

Palmitate and Nitric Oxide Regulate the Expression of Spexin and Galanin Receptors 2 and 3 in Hypothalamic Neurons.

GALR3 GALR2

2.86e-053108231730796
Pubmed

Sterol regulatory element-binding proteins are regulators of the NIS gene in thyroid cells.

SREBF1 TSHR

2.86e-053108223542164
InteractionHTR1D interactions

HTR1A HTR1B HTR1D

5.17e-0741033int:HTR1D
InteractionSYT1 interactions

TSHR SYT2 LRP1B LRP2 CD63 SYT5 HTT

1.12e-061051037int:SYT1
InteractionSLC17A2 interactions

ADCY3 ATP8A1 KCNT2 SLC12A4 ALG9

9.82e-06561035int:SLC17A2
InteractionHTR1A interactions

HTR1A HTR1B HTR1D TGFBR2

2.35e-05331034int:HTR1A
InteractionTTYH1 interactions

ATP7B ADGRL1 ADCY3 ATP8B2 ATP8A1 KCNT2 SLC12A4 ALG9 PIGW

2.35e-053001039int:TTYH1
InteractionATM interactions

USP34 LPAR4 POLR2A SREBF1 AMIGO1 LPAR6 MTRR ATM RBM47

5.30e-053331039int:ATM
InteractionSLC22A4 interactions

SLC7A6 ATP8B2 SLC6A8 ALG9 SFXN3 PIGW ATM

5.85e-051921037int:SLC22A4
InteractionCNPY3 interactions

ATP8A2 LRRC32 TLR8 AMIGO1 ITPR1 ITPR2 BRICD5

6.66e-051961037int:CNPY3
InteractionSYT5 interactions

SYT2 SYT5 HTT

8.37e-05171033int:SYT5
InteractionTSPAN15 interactions

ZFYVE27 TM9SF3 ADGRL1 SLC7A6 CMTM6 LPAR6 PIGW CD63

8.64e-052761038int:TSPAN15
InteractionGPR17 interactions

ZFYVE27 HEATR5A ITPR2 CMTM6 SLC6A8 INTS2 ATM HTT

1.03e-042831038int:GPR17
GeneFamilyUDP glucuronosyltransferases

UGT1A10 UGT2A2 UGT1A9 UGT2A1

1.35e-0532834363
GeneFamily5-hydroxytryptamine receptors, G protein-coupled

HTR1A HTR1B HTR1D

2.58e-0513833170
GeneFamilyATPase phospholipid transporting

ATP8A2 ATP8B2 ATP8A1

4.08e-05158331210
GeneFamilySynaptotagmins

SYT2 SYT8 SYT5

6.06e-0517833765
GeneFamilyInositol 1,4,5-triphosphate receptors|Protein phosphatase 1 regulatory subunits

ITPR1 ITPR2

6.23e-053832297
GeneFamilyGalanin receptors

GALR3 GALR2

6.23e-053832226
GeneFamilySolute carriers

SLC25A34 SLC44A2 SLC6A15 SLC44A4 SLC7A6 SLC2A5 SLC6A8 SLC9A3 SLC12A4

8.17e-05395839752
GeneFamilyAdhesion G protein-coupled receptors, subfamily L

ADGRL1 ADGRL2

1.24e-044832918
GeneFamilySideroflexins

SFXN1 SFXN3

2.06e-045832746
GeneFamilyLysophosphatidic acid receptors

LPAR4 LPAR6

3.09e-046832205
GeneFamilyCKLF like MARVEL transmembrane domain containing

CMTM1 CMTM6

5.73e-048832978
GeneFamilyLow density lipoprotein receptors

LRP1B LRP2

1.57e-0313832634
CoexpressionMACAEVA_PBMC_RESPONSE_TO_IR

POLR2A SPATA18 SLC7A6 PANK1 ITPR2 FGF10

4.92e-061061076M52
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

ZFYVE27 TM9SF3 SREBF1 SLC44A2 LMTK2 SLC7A6 ERGIC1 CMTM6 SLC12A4 ALG9 ADGRL2 HTT

2.24e-0568110712M5314
CoexpressionMILI_PSEUDOPODIA_HAPTOTAXIS_DN

ZFYVE27 TM9SF3 SREBF1 SLC44A2 LMTK2 SLC7A6 ERGIC1 CMTM6 SLC12A4 ALG9 ADGRL2 HTT

3.06e-0570310712MM1055
CoexpressionMEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3

PAQR9 MDFIC HTR1A HTR1B ATP7B GALR3 SYT2 ADGRV1 TGFBR2 SLC9A3 SLC12A4 PTCH2 LRP2 CD63 PLD5

3.10e-05107410715M1941
CoexpressionAtlasDevelopingKidney_e15.5_early proxim tubul_emap-28005_k-means-cluster#1_top-relative-expression-ranked_200

PAQR9 GLYAT UGT1A10 SLC44A4 LRP2

2.07e-06441015gudmap_developingKidney_e15.5_early proxim tubul_200_k1
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#2

HTR1A HTR1D LPAR4 CNFN ATP8A2 SYT2 ADGRV1 SLC44A4 TMEM132B PTCHD1 KCNT2 RBM47

1.28e-0555410112Arv_SC_fibroblast_1000_K2
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#1

HTR1A HTR1D LPAR4 CNFN ATP8A2 SYT2 ADGRV1 SLC44A4 TMEM132B PTCHD1 KCNT2 RBM47

1.35e-0555710112Arv_SC-HD_1000_K1
CoexpressionAtlasDevelopingKidney_e15.5_S-shaped body_emap-27855_k-means-cluster#5_top-relative-expression-ranked_200

GLYAT UGT1A10 LRP2 RBM47

6.18e-05451014gudmap_developingKidney_e15.5_S-shaped body_200_k5
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_200

GLYAT UGT1A10 SLC6A15 SLC44A4 LRP2 RBM47

7.90e-051491016gudmap_developingKidney_e15.5_Proximal Tubules_200
ToppCell10x5'-Liver-Lymphocytic_B-ABC_aged-B_memory|Liver / Manually curated celltypes from each tissue

CNFN ST6GAL1 WDFY4 SSPN RNFT2 SHOC1 TNFRSF13B

2.04e-071711087eb47f4a09a630ed14a0898377039ed50ef7cc292
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 LRP1B KCNT2 LRP2 FGF10 PLD5

2.61e-061601086c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADGRV1 LRP1B KCNT2 LRP2 FGF10 PLD5

2.61e-06160108625c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8|blood / Manually curated celltypes from each tissue

USP34 ZFYVE27 ATP8B2 ITPR1 SFXN1 ATM

2.81e-061621086b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

POLR2A ADGRV1 LRP1B LRP2 CD63 PLD5

3.58e-06169108612bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LANCL3 DSC1 ATP8A2 MDFI GALR2 SYT8

4.38e-061751086f1394aacc8a94ca555dd19aaed5a18da99c6bf40
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LANCL3 DSC1 ATP8A2 MDFI GALR2 SYT8

4.38e-0617510867bf1194d93fbe2dbf9d953e0a32b2a6d88251ed1
ToppCellControl-B_cells-B_cells|Control / group, cell type (main and fine annotations)

ST6GAL1 WDFY4 ITPR1 SSPN TNFRSF13B ATM

4.52e-061761086d2c353783bd78dc24f28e00d917b88d8294fb5df
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT SFXN1 SLC6A8 LRP2 CD63 CDH18

4.67e-0617710869c7c6824b9011363851f084a500d665f025b026e
ToppCellfacs-Kidney-nan-24m-Epithelial-kidney_collecting_duct_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT SFXN1 SLC6A8 LRP2 CD63 CDH18

4.67e-0617710862bf639e9e801e5144462ffc957f5739e0dfcd500
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 LRP1B SVOPL ITPR1 ITPR2 SLC9A3

6.02e-061851086898a093757f86be3e18d2ef1f16a71f50ef81dc3
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.40e-06187108623a42c172d5cc36cb8793c0bc2ce357c6c8e5d39
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.40e-0618710865ce7cf02990465b6f793205e4be07e8337b3570a
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.40e-06187108617a37fc3a1d62fef3137e5ff26a84c0b8c80e124
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.40e-0618710861b0eb29394040555516677b9de75c15e769c4c53
ToppCelldroplet-Kidney-nan-18m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT ITPR1 SLC6A8 LRP2 CD63 RBM47

6.40e-061871086236e9857729670e87eed30fad58f49e1f56e4a85
ToppCellprimary_auditory_cortex_(A1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.40e-06187108611c773cf3dc1e725b7e4d8edd676c8a94a231d2a
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.60e-061881086c65fb9a3c910dd6166853f4f3a2f2c2411ccf03b
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.81e-061891086389ccb68acb82893709f256315111470cf4beed3
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.81e-06189108658465b9407fbce91cca8f199950d6e0054c38fbc
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid-Micro|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

6.81e-0618910867ac78441a15a82218deaafd47accff2ea5c8de20
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Endothelial_Myeloid|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ST6GAL1 WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

7.01e-061901086d4f954e0748898df69e1710df558564db703dd61
ToppCellCOVID-19-kidney-Technical/muscle_(PCT)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP8A2 GRM7 LRP1B LRP2 CDH18

2.26e-051391085a1945b07f177cde40e7eea03a19236ce76165857
ToppCellCOVID-19-kidney-Technical/muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP8A2 GRM7 LRP1B TMEM132B CDH18

2.26e-05139108513247bcb21c57c808657e0f543d6f134eeea7cc1
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SVOPL AMIGO1 FBXO24 PIGW CD63

2.68e-051441085121853910eeea1ea0642b3cc99f9200015480368
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP8A2 GRM7 LRP1B TMEM132B CDH18

3.05e-051481085d6ac5972267254651dfbe16bb4e9a62228093cc7
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HTR1B LRRC32 FAM170B KCNT2 TRIM60

3.05e-051481085dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar-Club_cell|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF186 GPR85 SLC44A4 BRICD5 TRIM60

3.15e-05149108582edfecb7981d8c336cf9da7aa7e2b3f7a017a3f
ToppCellE18.5-samps-Epithelial-Epithelial-non_alveolar|E18.5-samps / Age Group, Lineage, Cell class and subclass

RNF186 GPR85 SLC44A4 BRICD5 TRIM60

3.15e-05149108514a01ae540db8a350ea26a350b2e6ce6c07639d9
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 ATP8B2 PTCHD1 ATP8A1 TNFRSF13B

3.15e-05149108548fca6ae33d7722c024b43ce04f4dbce7b6b424b
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

ATP8A2 GRM7 TMEM132B PLD5 CDH18

4.30e-0515910855335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCell368C-Fibroblasts-Fibroblast-E|368C / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 GRM7 ATP8B2 SSPN PLD5

4.70e-051621085e17632778a57c71d6005d3abca3a0443a92040e7
ToppCell368C-Fibroblasts-Fibroblast-E-|368C / Donor, Lineage, Cell class and subclass (all cells)

SPATA18 GRM7 ATP8B2 SSPN PLD5

4.70e-051621085ac4a80fd72c9311ea2b3e574c6284bbce4f2756c
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_naive|bone_marrow / Manually curated celltypes from each tissue

CNFN ST6GAL1 WDFY4 SSPN TNFRSF13B

4.70e-05162108544832055b11a789e320c802aadb345e065defc8f
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 ADCY3 SORT1 FBXO24 ATP8A1

4.84e-0516310858dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tfh|GI_large-bowel / Manually curated celltypes from each tissue

LANCL3 SREBF1 ADGRV1 GALR2 ATP8B2

4.84e-0516310854104d3b9748b39cb0744c9be76db21bdda566a0d
ToppCelldroplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDFY4 ADCY3 SORT1 FBXO24 ATP8A1

4.84e-051631085fd243ca223079033be480a24817a399f281fa4d4
ToppCell10x5'-bone_marrow-Lymphocytic_B-ABC_aged-B_memory|bone_marrow / Manually curated celltypes from each tissue

CNFN ST6GAL1 WDFY4 SSPN TNFRSF13B

4.98e-051641085746833f74095c0f25ce76baf1069f1848c231933
ToppCellControl-B_cells-Activated_B_cells|Control / group, cell type (main and fine annotations)

ST6GAL1 WDFY4 SSPN TNFRSF13B ATM

5.59e-051681085a7159a35fe37f8c241cf8d391debe271e0698105
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B-Memory_B_cells|GI_small-bowel / Manually curated celltypes from each tissue

SLC6A15 ST6GAL1 WDFY4 SSPN TNFRSF13B

5.59e-0516810858e025bb0541746e232b77ac0e31412ae71420c47
ToppCell3'_v3-GI_small-bowel-Lymphocytic_B|GI_small-bowel / Manually curated celltypes from each tissue

SLC6A15 ST6GAL1 WDFY4 SSPN TNFRSF13B

5.59e-0516810855535c1b8b7fde7b59a1bc0580cebdfa963aa1c39
ToppCellP15-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RNF186 ATP7B ATP8A1 LRP2 RBM47

5.91e-0517010856c0619cbe2f01a6de18da0a137f92bda0cbdf075
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_B|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ST6GAL1 WDFY4 SSPN TNFRSF13B ATM

5.91e-051701085a965e3ee6818790a4a6916824fde64333d9b11b7
ToppCellP28-Epithelial-epithelial_progenitor_cell-epithelial_progenitor_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RNF186 ATP7B ATP8A1 LRP2 RBM47

5.91e-051701085d0ed3a8a7ad96c05641ec409b0a69c4fb094893c
ToppCellChildren_(3_yrs)-Immune-B_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ST6GAL1 WDFY4 ITPR1 SSPN TNFRSF13B

5.91e-051701085e421f9eedf74baffda1d03707a710ece4b777f29
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TM9SF3 ST6GAL1 SLC44A4 UGT2A1 CD63

6.42e-0517310853aa1d28d4814798a772808ed29e1dbbdf92abd03
ToppCellfacs-Trachea-nan-24m-Mesenchymal-chondrocyte|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATP8A2 MDFI GALR2 SYT8 TAS1R2

6.42e-0517310852226505610af1becc253d0a5550627144ef0ed6b
ToppCellBL-critical-LOC-Lymphoid-PC|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TSHR SLC2A5 SSPN ALG9 TNFRSF13B

6.42e-05173108590700a876d997f7c0f7b3899dffcda7fdafee547
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TM9SF3 ST6GAL1 SLC44A4 UGT2A1 CD63

6.42e-051731085e8afef5ae68983eb8d6515b43952636a47e9d3d4
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell-B_c04-SOX5-TNFRSF1B|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CNFN ST6GAL1 WDFY4 SSPN TNFRSF13B

6.60e-051741085ebe6ce173ad12d4a2afa39f8d6185c0e4f97fb1e
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_II_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

RNF186 ATP7B ATP8A1 LRP2 RBM47

6.78e-0517510858a4ed775ff973123dbcfe9c809959d11a62450c9
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DSC1 ADGRV1 LRP1B KCNT2 LRP2

6.78e-051751085887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCellControl-B_cells|Control / group, cell type (main and fine annotations)

ST6GAL1 WDFY4 SSPN TNFRSF13B ATM

6.96e-0517610859125caa27bf790f6b1b960a86c09b4bcb1b58641
ToppCellCOVID-19-lung-B_cells|lung / Disease (COVID-19 only), tissue and cell type

ST6GAL1 WDFY4 ITPR1 SSPN TNFRSF13B

7.15e-051771085f54691e5558091c1734ab15153a10bff15ed171e
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

ST6GAL1 WDFY4 ITPR1 SSPN TNFRSF13B

7.15e-051771085653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CNFN WDFY4 PTCHD1 SSPN TNFRSF13B

7.35e-051781085be1d991c5a0a5be22f14f57d34ee1330f1a12963
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT RNF186 TMEM132B SLC2A5 LRP2

7.35e-05178108558857bb8c13e0e1c6d9f5c1258f00fff62063d68
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT RNF186 TMEM132B SLC2A5 LRP2

7.35e-0517810858b7df6ab8709d9ab9dff97677cc4561aec2745bc
ToppCelldroplet-Fat-BAT+GAT+MAT-30m-Epithelial-epithelial_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT RNF186 TMEM132B SLC2A5 LRP2

7.35e-051781085b0baf5667e3301898b3e45e974b8a8530af6a338
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CNFN ST6GAL1 WDFY4 SSPN TNFRSF13B

7.54e-051791085a28a1de500a74c6dcc43481abf9ec0f7e7a300a9
ToppCellChildren_(3_yrs)-Immune-B_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC44A2 ST6GAL1 WDFY4 SSPN TNFRSF13B

7.74e-05180108540a12eb852373ae3d7c8d9bca376b0ae99f724b3
ToppCell5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Multiciliated_(nasal)-Multiciliated_(nasal)_L.0.3.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SPATA18 SLC44A4 GRM7 SYT8 RNFT2

7.74e-0518010851f1af4474f3f0ac3c0d6b1a6c875c354d36d8eec
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B-B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ST6GAL1 WDFY4 ITPR1 TNFRSF13B ATM

7.95e-0518110858d8cc4dae2c8bd5f4b1c159f2a52edc4c9449c86
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TM9SF3 ST6GAL1 CACFD1 SLC44A4 CD63

8.16e-05182108594e70746e35a3062015d4b83ee545f4f84f47420
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY3 SORT1 TGFBR2 CD63 TMEM64

8.16e-051821085be48ce85991bceeff938ba080e6bf9cc62176b05
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 LRP1B PANK1 ITPR2 SLC9A3

8.16e-051821085041bc819e6cf2618bf86bce8dfe2df673f392ba3
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT RNF186 SFXN1 LRP2 CD63

8.37e-05183108592f54c267135cb5edbcacd26a0f29e62469bb7e5
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GLYAT ADGRV1 SLC44A4 UGT2A1 LRP2

8.37e-051831085d73cac83cde82665f110baad7cf28db75f9ffe52
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 LRP1B ITPR1 ITPR2 SLC9A3

8.37e-05183108531ab55d5f3639f5964541d5eae23044dbda3356e
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ATP7B SLC44A4 ATP8A1 TMIE LRP2

8.37e-05183108523e55f88a802a9299d2773f9394970e86e8bbfaa
ToppCellPND07-28-samps-Epithelial-Alveolar_epithelial-AT2|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ATP7B SLC44A4 ATP8A1 TMIE LRP2

8.37e-0518310850a69e22750dd8b66ab988cf36d0dd2b59e2f7d26
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____kidney_proximal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GLYAT RNF186 SFXN1 LRP2 CD63

8.37e-0518310855c4f7d02ba3a3c4a22ac71302e7c9a47e205eef5
ToppCellnucseq-Immune-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ST6GAL1 WDFY4 SSPN TNFRSF13B ATM

8.59e-051841085911658e7bb499c1bbc8419eec8ff88729bc39a75
ToppCelldroplet-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITPR1 SLC6A8 LRP2 CD63 RBM47

8.59e-051841085e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ToppCelldroplet-Marrow-nan-3m-Lymphocytic-late_pro-B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ST6GAL1 ERGIC1 SYT5 ADGRL2 RBM47

8.59e-05184108542cadfdb5d29a50bd7e901ddd14d42b39e8474f0
ToppCellnucseq-Immune-Lymphocytic_B-Lymphocytic_B|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ST6GAL1 WDFY4 SSPN TNFRSF13B ATM

8.59e-051841085942b58ae7172bb5f97e55b032db9329d161854af
ToppCell10x5'-Liver-Lymphocytic_B_plasma-Plasma_cells|Liver / Manually curated celltypes from each tissue

ST6GAL1 TSHR SLC2A5 SSPN TNFRSF13B

8.59e-0518410856f70d8f8ab8362d51f8a58735d42223e06566397
ToppCellCOPD-Lymphoid-B|COPD / Disease state, Lineage and Cell class

USP34 ST6GAL1 WDFY4 SSPN TNFRSF13B

8.81e-051851085925e79c35c381dd44ec5fb921dca09ce43140135
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.04e-051861085e41f14aee8cfbf76b8d0d4695a6170e2cd92aec8
ToppCellChildren_(3_yrs)-Immune-B_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

ST6GAL1 WDFY4 ITPR1 SSPN TNFRSF13B

9.04e-051861085aa576748921a318798b911a611f05319b95e8d5e
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.04e-051861085b3633cd4e360c5b45060c50b4f606d483e03a89a
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Endothelial_Myeloid-Micro|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.04e-0518610859dd31dc9af1704f35c74de726a6c27fa21e9a014
ToppCellControl-Lymphoid-B_Plasma|Lymphoid / Disease state, Lineage and Cell class

ST6GAL1 SSPN PTCH2 TNFRSF13B RBM47

9.04e-051861085a08a50bff4e629588faa22440d57334b1df0e8df
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

GRM7 LRP1B SVOPL ADGRL2 GPR132

9.27e-05187108577886f99c229610abd28c4c370d2c7d1536c9782
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

ST6GAL1 WDFY4 ITPR1 SSPN TNFRSF13B

9.27e-051871085af1327559f7e01bec070881cae52834917c3da65
ToppCelldroplet-Kidney-nan-18m-Epithelial-Pecam____Kidney_cortex_artery_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRRC32 PTCHD1 SSPN KCNT2 SYT8

9.27e-051871085e93cad16a087d1443cbf4e1690dc1b35d7a84c41
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.50e-05188108526c0a94951236a5d17a169920b0a8a9d0dd7d0ed
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.50e-051881085af300574c4e95505f56bf716bcee1e4777944e8e
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.50e-0518810855df5a0890e17d19f55770525345a656253696887
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Endothelial_Myeloid-Micro|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.50e-051881085e169e9bb85892e52880ee949d0f691d0ea0c8dc9
ToppCellmild_COVID-19-CD8+_T_naive|mild_COVID-19 / disease group, cell group and cell class (v2)

DSC1 ATP8A2 SFXN1 TGFBR2 ATM

9.50e-05188108560d27014e5f9e562efe2a602482ea1d07efd0331
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 LRP1B SVOPL ITPR1 SLC9A3

9.50e-0518810852ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.50e-0518810859e923b0d79495ee1a3a097741a877f25d439eda3
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-6|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CNFN ST6GAL1 WDFY4 SSPN TNFRSF13B

9.50e-05188108518d16e3f095a109b6a690f46fe7fcd5674c3636b
ToppCellMid-temporal_gyrus_(MTG)-Non-neuronal-Endothelial_Myeloid-Micro|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

WDFY4 SLC2A5 TGFBR2 LPAR6 RBM47

9.50e-05188108514dbc985abc2012c9f53deb243d465e4175f419f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RNF186 TM9SF3 ST6GAL1 SLC44A4 UGT2A1

9.50e-0518810855901b276f2379abf486b8285957277e95f08464e
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ST6GAL1 TSHR ATP8B2 SLC2A5 TNFRSF13B

9.50e-051881085567b08514d9d84cbb40f9b7a679eec304f023428
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRV1 GRM7 LRP1B SVOPL SLC9A3

9.50e-0518810853cee9916399e2e7580cecbcbb27424a71e7e7ac0
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ADCY3 SORT1 TGFBR2 CD63 TMEM64

9.74e-05189108598f517af255ef234eefc3ed7e6c1d63331ab8af0
ToppCell10x5'-Liver-Lymphocytic_B|Liver / Manually curated celltypes from each tissue

CNFN ST6GAL1 WDFY4 SSPN TNFRSF13B

9.74e-0518910851ebff8185060d78f27f8d887e9adaa5f8faf2196
Drugspirilene

HTR1A HTR1B HTR1D

1.04e-0731083CID006436870
Drugsumatriptan

HTR1A HTR1B HTR1D LPAR4 ADCY3 LPAR6 MTRR

1.06e-07801087CID000005358
DrugZolmitriptan

HTR1A HTR1B HTR1D

4.14e-0741083DB00315
DrugIs 159

HTR1A HTR1B HTR1D

4.14e-0741083CID000196859
DrugPD 158771

HTR1A HTR1B HTR1D

4.14e-0741083CID003075615
DrugNaratriptan

HTR1A HTR1B HTR1D

4.14e-0741083DB00952
DrugLY206130

HTR1A HTR1B HTR1D

4.14e-0741083CID000124433
DrugSumatriptan

HTR1A HTR1B HTR1D

4.14e-0741083DB00669
DrugPD 118717

HTR1A HTR1B HTR1D

4.14e-0741083CID000128518
DrugSKF 99101H

HTR1A HTR1B HTR1D

4.14e-0741083CID000182576
Drugsodium cholate

UGT1A10 GPR85 SREBF1 UGT1A9 LRP1B CMTM1 SLC12A4 UGT2A1 LRP2 MTRR HSD17B3 HTT

5.53e-0740810812CID000000303
Drugacotiamide

HTR1A HTR1B HTR1D UGT1A10 UGT1A9

8.45e-07371085CID005282338
DrugTrelibet

HTR1A HTR1B HTR1D

1.03e-0651083CID000065975
Drugeptapirone

HTR1A HTR1B HTR1D

1.03e-0651083CID000208928
DrugCP-135,807

HTR1A HTR1B HTR1D

1.03e-0651083CID005487088
Drug4-amino-5-chloro-2-methoxybenzamide

HTR1A HTR1B HTR1D

1.03e-0651083CID009834239
DrugI 370

HTR1A HTR1B HTR1D

1.03e-0651083CID000089576
Drugcentbutindole

HTR1A HTR1B HTR1D

1.03e-0651083CID000068663
DrugCP-132,484

HTR1A HTR1B HTR1D

1.03e-0651083CID000132564
DrugAC1LCKBJ

HTR1A HTR1B HTR1D

1.03e-0651083CID000601768
DrugSan 21009

HTR1A HTR1B HTR1D ADCY3

1.09e-06171084CID000152662
DrugDP-5-CT

HTR1A HTR1B HTR1D MTRR

1.39e-06181084CID000156314
Drug8-OH-DPAT

HTR1A HTR1B HTR1D GALR3 GALR2 ADCY3 MTRR

1.43e-061171087CID000001220
DrugNeurotensin (1-6)

HTR1B HTR1D SORT1

2.05e-0661083CID000137323
Drugpyrrolo(1,2-a)quinoxaline

HTR1A HTR1B HTR1D

2.05e-0661083CID000067476
Drug(125i)gti

HTR1A HTR1B HTR1D

2.05e-0661083CID000131670
DrugR 28935

HTR1A HTR1B HTR1D

2.05e-0661083CID000093307
Drugniaprazine

HTR1A HTR1B ATM

2.05e-0661083CID000071919
Drug5-aminotryptamine

HTR1A HTR1B HTR1D

2.05e-0661083CID003083677
DrugNDO 008

HTR1A HTR1B HTR1D

2.05e-0661083CID000131001
Drugclonidine

GLYAT HTR1A HTR1B HTR1D LPAR4 GALR3 GALR2 ADCY3 LPAR6

2.19e-062401089CID000002803
DrugGSK835726

HTR1A GALR3 GALR2 ADCY3

3.28e-06221084CID005311268
Drugalpha-methylserotonin

HTR1A HTR1B HTR1D MTRR

3.28e-06221084CID000115292
DrugGR127935

HTR1A HTR1B HTR1D MTRR

3.28e-06221084CID000107780
Drugadafenoxate

HTR1A HTR1B HTR1D

3.58e-0671083CID000064517
DrugEletriptan

HTR1A HTR1B HTR1D

3.58e-0671083DB00216
DrugBRL 34778

HTR1A HTR1B HTR1D

3.58e-0671083CID000135770
DrugNAD-299

HTR1A HTR1B HTR1D

3.58e-0671083CID000451066
Drug2,2'-pyridylisatogen

HTR1A HTR1B ATP8A2

3.58e-0671083CID000124333
DrugLY334370

HTR1A HTR1B HTR1D

3.58e-0671083CID005311258
Drug[18f]fbway 1,3 N

HTR1A HTR1B HTR1D

3.58e-0671083CID005352127
Drugbaclofen

GLYAT HTR1A HTR1B HTR1D GRM7 ADCY3 ITPR1 MTRR

3.64e-061911088CID000002284
DrugBP-554

HTR1A HTR1B HTR1D

5.71e-0681083CID000134117
DrugAC1L5AAF

HTR1A HTR1B HTR1D

5.71e-0681083CID000173615
DrugSB 216641

HTR1A HTR1B HTR1D

5.71e-0681083CID003292447
Drugcinitapride

HTR1A HTR1B HTR1D

5.71e-0681083CID000068867
Drugcarmoxirole

HTR1A HTR1B HTR1D

5.71e-0681083CID000057364
DrugS 14489

HTR1A HTR1B HTR1D

5.71e-0681083CID000182595
Drug5-OHIP

HTR1A HTR1B HTR1D

5.71e-0681083CID000182581
Drug5-fluoro-alpha-methyltryptamine

HTR1A HTR1B HTR1D

5.71e-0681083CID000012834
Drugmirtazapine

HTR1A HTR1B HTR1D GPR85 SLC2A5

5.75e-06541085CID000004205
Drug5-CT

HTR1A HTR1B HTR1D ADCY3 MTRR

6.30e-06551085CID000001809
Drugcyproheptadine

HTR1A HTR1B HTR1D UGT1A10 UGT1A9 MTRR

6.49e-06961086CID000002913
Drugnorclozapine

HTR1A HTR1B HTR1D UGT1A10 UGT1A9

7.53e-06571085CID000002820
DrugAC1NB8R3

GLYAT HTR1B HTR1D ATP7B GRM7 CD63 ATM HTT

8.12e-062131088CID004489307
Drugmelantonin

HTR1A HTR1B HTR1D

8.54e-0691083CID000077899
DrugCQ 32-084

HTR1A HTR1B HTR1D

8.54e-0691083CID000068847
DrugAHPP

HTR1A HTR1B HTR1D

8.54e-0691083CID000128891
DrugS 15931

HTR1A HTR1B HTR1D

8.54e-0691083CID000182596
DrugU91356A

HTR1A HTR1B HTR1D

8.54e-0691083CID000132955
DrugL-741,626

HTR1A HTR1B HTR1D CD63

8.98e-06281084CID000133633
Drug5-OH-DPAT

HTR1A HTR1B HTR1D

1.22e-05101083CID000172267
DrugCM 29-712

HTR1A HTR1B HTR1D

1.22e-05101083CID000159842
DrugYohimbine

HTR1A HTR1B HTR1D

1.22e-05101083DB01392
DrugBIMT 17 BS

HTR1A HTR1B HTR1D

1.22e-05101083CID006918248
Drug5-HTQ

HTR1A HTR1B HTR1D

1.22e-05101083CID000656705
Drug2-(di-n-propylamino)tetralin

HTR1A HTR1B HTR1D

1.22e-05101083CID000090285
Drugseganserin

HTR1A HTR1B HTR1D

1.22e-05101083CID000071767
DrugS 14671

HTR1A HTR1B HTR1D

1.22e-05101083CID000131907
DrugS 14297

HTR1A HTR1B HTR1D

1.22e-05101083CID000115007
DrugLY344864

HTR1A HTR1B HTR1D

1.22e-05101083CID005311097
DrugAC1L1CCX

HTR1A HTR1B HTR1D

1.22e-05101083CID000001840
DrugU-86170F

HTR1A HTR1B HTR1D

1.22e-05101083CID000131559
DrugSDZ 208-912

HTR1A HTR1B HTR1D

1.22e-05101083CID000058145
DrugYM-09151-2

HTR1A HTR1B HTR1D MTRR

1.55e-05321084CID000004452
Drug3-nitro-4-hydroxyphenylacetic acid

GLYAT HTR1B HTR1D TSHR PTCH2 ATM

1.58e-051121086CID000447364
Drugbefloxatone

HTR1A HTR1B HTR1D

1.67e-05111083CID000060824
Drugalniditan

HTR1A HTR1B HTR1D

1.67e-05111083CID000066004
DrugAC1Q6F2A

HTR1A HTR1B HTR1D

1.67e-05111083CID000060621
Drugiodocyanopindolol

HTR1A HTR1B HTR1D ADCY3

1.76e-05331084CID000068618
Drughaloperidol

HTR1A HTR1B HTR1D GRM7 ADCY3 SORT1 CMTM1 MTRR SYT5 HTT

1.84e-0539410810CID000003559
Drugphenylbiguanide

HTR1A HTR1B HTR1D MTRR

1.99e-05341084CID000004780
DrugBRL15572

HTR1A HTR1B HTR1D

2.21e-05121083CID003654103
DrugAMN082

HTR1B HTR1D GRM7

2.21e-05121083CID001894360
Drugxestospongin C

ITPR1 ITPR2 HTT

2.21e-05121083ctd:C511704
Drugsergolexole

HTR1A HTR1B HTR1D

2.21e-05121083CID000060262
Drugocaperidone

HTR1A HTR1B HTR1D

2.21e-05121083CID000071351
Drug6,7-DHT

HTR1B HTR1D

2.23e-0521082CID000039719
Drug8-methoxy-2'-chloro-PAT

HTR1A HTR1B

2.23e-0521082CID000125955
DrugG-6-M

GLYAT ATM

2.23e-0521082CID000065891
Drug5-methoxy 3-(1,2,3,6-tetrahydro-4-pyridinyl)1H indole

HTR1A HTR1B

2.23e-0521082ctd:C025145
DrugJMC-181

HTR1B HTR1D

2.23e-0521082CID000134385
Drug8-Azabicyclo[3.2.1]oct-2-ene

HTR1A HTR1B

2.23e-0521082CID000138546
DrugN,N-dipropyl-6,7-ADTN

HTR1B HTR1D

2.23e-0521082CID000125246
DrugFrovatriptan

HTR1B HTR1D

2.23e-0521082DB00998
DrugAlmotriptan

HTR1B HTR1D

2.23e-0521082DB00918
Drug3-(4-piperidyl)-1H-indole

HTR1A HTR1B

2.23e-0521082CID000702235
Drugtertatolol

HTR1A HTR1B

2.23e-0521082ctd:C005632
DrugPD 128483

HTR1B HTR1D

2.23e-0521082CID000130792
Drugnaratriptan

HTR1B HTR1D

2.23e-0521082ctd:C106783
Diseasecongenital myasthenic syndrome 7 (implicated_via_orthology)

SYT2 SYT8 SYT5

1.70e-0741043DOID:0110659 (implicated_via_orthology)
Diseaseneuromuscular junction disease (implicated_via_orthology)

SYT2 SYT8 SYT5

4.23e-0751043DOID:439 (implicated_via_orthology)
Diseasegeneralized anxiety disorder (implicated_via_orthology)

HTR1A HTR1B HTR1D

2.35e-0681043DOID:14320 (implicated_via_orthology)
DiseaseProstatic Neoplasms

ATP7B SPATA18 LMTK2 LRP1B ITPR1 TGFBR2 RNASEL LRP2 FGF10 ATM HSD17B3

1.16e-0561610411C0033578
DiseaseMalignant neoplasm of prostate

ATP7B SPATA18 LMTK2 LRP1B ITPR1 TGFBR2 RNASEL LRP2 FGF10 ATM HSD17B3

1.16e-0561610411C0376358
DiseaseInherited neuropathies

ZFYVE27 ITPR1 NIPA1 ATM

1.21e-05401044C0598589
DiseaseHypoxic Brain Damage

ITPR1 ITPR2

1.23e-0521042C1140716
DiseaseAnoxic Encephalopathy

ITPR1 ITPR2

1.23e-0521042C0003132
DiseaseBrain Hypoxia

ITPR1 ITPR2

1.23e-0521042C1527348
DiseaseAnoxia of brain

ITPR1 ITPR2

1.23e-0521042C0995195
DiseaseAbnormality of the sense of smell, COVID-19 symptoms measurement, ageusia

UGT2A2 UGT2A1

1.23e-0521042EFO_0600019, EFO_1001758, HP_0004408
Diseasecongenital myasthenic syndrome (implicated_via_orthology)

SYT2 SYT8 SYT5

2.30e-05161043DOID:3635 (implicated_via_orthology)
DiseaseMajor Depressive Disorder

HTR1A HTR1B ATP7B GALR3 SLC6A15 GRM7 GALR2

2.54e-052431047C1269683
Diseaseindole-3-carboxylate measurement

UGT1A10 UGT1A9

3.68e-0531042EFO_0800043
Diseaseblood 4-oxo-retinoic acid measurement

UGT1A10 UGT1A9

3.68e-0531042EFO_0022216
Diseasehepcidin:ferritin ratio

GLYAT LRRC32 LRP1B AMIGO1

4.33e-05551044EFO_0007901
DiseaseN-acetyl-4-chlorophenylalanine measurement

UGT1A10 UGT1A9

1.22e-0451042EFO_0801060
Disease5-hydroxyindole sulfate measurement

UGT1A10 UGT1A9

1.22e-0451042EFO_0800085
Diseasenuclear receptor subfamily 1 group D member 2 measurement

UGT1A10 UGT1A9

1.22e-0451042EFO_0801853
Diseaseattention deficit hyperactivity disorder (implicated_via_orthology)

ADGRL1 PTCHD1 ADGRL2

1.31e-04281043DOID:1094 (implicated_via_orthology)
Diseasexanthurenate measurement

UGT1A10 UGT1A9 GRM7

1.45e-04291043EFO_0010551
DiseaseChild Development Disorders, Specific

WDFY4 SLC6A8 LRP2

1.45e-04291043C0085997
DiseaseChild Development Deviations

WDFY4 SLC6A8 LRP2

1.45e-04291043C0085996
DiseaseDevelopmental Disabilities

WDFY4 SLC6A8 LRP2

1.61e-04301043C0008073
Diseasetype 2 diabetes mellitus (biomarker_via_orthology)

UGT1A10 SREBF1 UGT1A9 TGFBR2 HSD17B3

1.77e-041471045DOID:9352 (biomarker_via_orthology)
Disease3-carboxy-4-methyl-5-pentyl-2-furanpropionate (3-CMPFP) measurement

UGT1A10 UGT1A9

1.83e-0461042EFO_0800566
Diseaseglucagon measurement

GRM7 ITPR1 PLD5 ADGRL2 NLRP8

2.20e-041541045EFO_0008463
DiseaseX-21339 measurement

UGT1A10 UGT1A9

2.55e-0471042EFO_0800808
DiseaseUnipolar Depression

HTR1A HTR1B ATP7B SLC6A15 GRM7 GALR2

3.19e-042591046C0041696
DiseaseAutistic Disorder

HTR1B HTR1D WDFY4 SLC6A8 PTCHD1 PLD5

3.33e-042611046C0004352
DiseaseX-11793--oxidized bilirubin measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0021260
DiseaseSuccinimide measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0022118
DiseaseX-11530 measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0021249
Diseasesulfate of piperine metabolite C16H19NO3 (2) measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0801034
Diseasecholelithiasis, bilirubin measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0004570, EFO_0004799
DiseaseX-11522 measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0800696
DiseaseX-10458 measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0800692
DiseaseX-24849 measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0800909
Diseaseserum N-desmethylclozapine measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0600043
Diseaseplasma clozapine measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0600038
Diseasemembrane-associated progesterone receptor component 1 measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0802740
DiseaseX-16946 measurement

UGT1A10 UGT1A9

3.40e-0481042EFO_0800766
DiseaseX-11442 measurement

UGT1A10 UGT1A9

4.36e-0491042EFO_0021236
DiseaseX-11441 measurement

UGT1A10 UGT1A9

4.36e-0491042EFO_0021235
Diseasecirculating cell free DNA measurement

UGT1A10 UGT1A9

4.36e-0491042EFO_0004739
Diseasesulfate of piperine metabolite C18H21NO3 (3) measurement

UGT1A10 UGT1A9

4.36e-0491042EFO_0801037
Diseasesulfate of piperine metabolite C18H21NO3 (1) measurement

UGT1A10 UGT1A9

4.36e-0491042EFO_0801036
DiseaseX-11880 measurement

UGT1A10 UGT1A9

4.36e-0491042EFO_0800698
Diseaseprotein-tyrosine kinase 6 measurement

UGT1A10 UGT1A9

4.36e-0491042EFO_0020691
Diseasetestis-specific chromodomain protein Y 1 measurement

UGT1A10 UGT1A9

4.36e-0491042EFO_0802127
Diseasebilirubin measurement, response to xenobiotic stimulus

UGT1A10 UGT1A9

4.36e-0491042EFO_0004570, GO_0009410
Diseasebilirubin measurement, response to tenofovir

UGT1A10 UGT1A9

5.44e-04101042EFO_0004570, EFO_0009279
Diseaseindoleacetate measurement

UGT1A10 UGT1A9

5.44e-04101042EFO_0021015
DiseaseX-21448 measurement

UGT1A10 UGT1A9

5.44e-04101042EFO_0800816
DiseaseUDP-glucuronosyltransferase 1-6 measurement

UGT1A10 UGT1A9

5.44e-04101042EFO_0802185
DiseaseX-23974 measurement

UGT1A10 UGT1A9

5.44e-04101042EFO_0800867
DiseaseDepressive disorder

HTR1A HTR1B HTR1D GRM7 GALR2 HTT

5.70e-042891046C0011581
Diseaseapolipoprotein B measurement

PAQR9 UGT1A10 SLC44A2 UGT1A9 AMIGO1 SORT1 CMTM6 RBM47 HTT

5.71e-046631049EFO_0004615
Diseasepregnenetriol sulfate measurement

UGT1A10 UGT1A9

6.63e-04111042EFO_0800586
Diseaseplasma N-desmethylclozapine measurement

UGT1A10 UGT1A9

6.63e-04111042EFO_0600039
Diseasehistidine betaine (hercynine) measurement

UGT1A10 UGT1A9

6.63e-04111042EFO_0800972
DiseaseX-21796 measurement

UGT1A10 UGT1A9

6.63e-04111042EFO_0800825
Diseaseinsomnia, bilirubin measurement

UGT1A10 UGT1A9

6.63e-04111042EFO_0004570, EFO_0004698
Diseasealdosterone measurement

UGT1A10 UGT1A9

6.63e-04111042EFO_0010219
Diseaseautosomal dominant cerebellar ataxia (implicated_via_orthology)

ITPR1 ITPR2

7.94e-04121042DOID:1441 (implicated_via_orthology)
Diseasep-cresol glucuronide measurement

UGT1A10 UGT1A9

7.94e-04121042EFO_0800079
Diseasebiliverdin measurement

UGT1A10 UGT1A9

7.94e-04121042EFO_0021033
Diseasecreatinine measurement, glomerular filtration rate

SLC7A6 SORT1 LRP2 ADGRL2

7.95e-041171044EFO_0004518, EFO_0005208
Diseasemetabolite measurement

UGT1A10 SREBF1 UGT1A9 SLC7A6 WDFY4 SVOPL ITPR2 TGFBR2

8.38e-045601048EFO_0004725
DiseaseHypotension

HTR1B HTR1D SLC9A3

8.77e-04531043C0020649
Diseasepregnenetriol disulfate measurement

UGT1A10 UGT1A9

9.36e-04131042EFO_0800587
DiseaseX-24588 measurement

UGT1A10 UGT1A9

9.36e-04131042EFO_0800898
Diseaseretinol dehydrogenase 16 measurement

UGT1A10 UGT1A9

9.36e-04131042EFO_0802007
Diseasetrimethylamine-N-oxide measurement

ITPR2 TAS1R2

1.09e-03141042EFO_0010541
Diseaseurate measurement, spine bone mineral density

UGT1A10 UGT1A9 ADGRL1

1.14e-03581043EFO_0004531, EFO_0007701
Diseaselow density lipoprotein cholesterol measurement, body fat percentage

UGT1A10 UGT1A9

1.62e-03171042EFO_0004611, EFO_0007800
DiseaseX-21441 measurement

UGT1A10 UGT1A9

1.62e-03171042EFO_0800814
Diseaseangiopoietin-related protein 1 measurement

UGT1A10 UGT1A9

1.81e-03181042EFO_0801382
Diseasemigraine disorder, endometriosis

POLR2A GRM7 LRP1B

2.21e-03731043EFO_0001065, MONDO_0005277
Diseasekidney disease (biomarker_via_orthology)

SREBF1 TGFBR2

2.47e-03211042DOID:557 (biomarker_via_orthology)
Diseasetissue factor measurement

UGT1A10 UGT1A9

2.47e-03211042EFO_0010623
Diseaseunipolar depression, bipolar disorder, schizophrenia, sex interaction measurement

LRP1B AMIGO1 SORT1

2.48e-03761043EFO_0003761, EFO_0008343, MONDO_0004985, MONDO_0005090
DiseaseParkinson's disease (is_implicated_in)

MTRR ATM HTT

2.48e-03761043DOID:14330 (is_implicated_in)
DiseaseAlcoholic Intoxication, Chronic

HTR1A HTR1B GALR3 GRM7 CDH18

2.64e-032681045C0001973
Diseaseanxiety disorder (implicated_via_orthology)

HTR1A HTR1B

2.71e-03221042DOID:2030 (implicated_via_orthology)
Diseasecomplement factor H-like 1 protein measurement

ATP8A2 KCNT2

2.71e-03221042EFO_0600092
DiseaseNonsyndromic Deafness

ADGRV1 SLC44A4 TMIE

2.97e-03811043C3711374
DiseaseMood Disorders

HTR1A HTR1B ADCY3 HTT

3.00e-031681044C0525045
Diseaseantiphospholipid syndrome

TSHR CDH18

3.23e-03241042EFO_0002689
DiseaseLynch syndrome (is_implicated_in)

TGFBR2 RNASEL

3.23e-03241042DOID:3883 (is_implicated_in)
Diseasesnoring measurement

POLR2A ADGRV1 ATP8A1

3.30e-03841043EFO_0008341
Diseasesquamous cell lung carcinoma, family history of lung cancer

SPATA18 SVOPL PLD5

3.41e-03851043EFO_0000708, EFO_0006953
DiseaseInvolutional paraphrenia

GALR3 GALR2

3.50e-03251042C1571983
DiseasePsychosis, Involutional

GALR3 GALR2

3.50e-03251042C1571984
DiseaseInvolutional Depression

GALR3 GALR2

3.50e-03251042C0011574

Protein segments in the cluster

PeptideGeneStartEntry
TCCTASILHLCVIAL

HTR1B

131

P28222
VVSCPAACLCASNIL

AMIGO1

31

Q86WK6
LAKCLDVPFAICDCT

CLPX

306

O76031
LIYLCIDICFPSNIC

BRICD5

236

Q6PL45
AFQTSITVLCIACPC

ATP7B

971

P35670
SLVCLAICISTFCFL

ADGRL1

871

O94910
FLRCLLAFVSCICEL

ALG9

141

Q9H6U8
MNAFILLLCEAPFCC

CACFD1

66

Q9UGQ2
CISGLCLAVLSHIFC

ADGRV1

5916

Q8WXG9
VISLVCLAICIFTFC

ADGRL2

856

O95490
FLDLALSCKAVICCR

ATP8A1

761

Q9Y2Q0
FLDLALSCKAVICCR

ATP8A2

781

Q9NTI2
LEFLETACACKAVIC

ATP8B2

791

P98198
LLGVCCSVDNCRLFI

RBM47

141

A0AV96
LVCETLQFLDCICGS

ITPR2

1951

Q14571
VLLLAFCACAVGLIA

CD63

16

P08962
CLDLACEFLCLLNPS

LRP1B

4176

Q9NZR2
ILACLFCEFLTLCNI

MDFIC

171

Q9P1T7
NLVCETLQFLDCICG

ITPR1

2006

Q14643
QILELENCLFTSICC

NLRP8

956

Q86W28
TLCLATLNCCFDPFI

LPAR4

296

Q99677
VDFCLLSDFIQEICC

SPATA18

411

Q8TC71
CACLLDLLLAFPSCQ

MTRR

421

Q9UBK8
FIERCIQTFPTCCLL

GLYAT

196

Q6IB77
CTDLLLACFICPAVV

GAPVD1

306

Q14C86
ICCCVLAVLPSLFLL

OR51Q1

151

Q8NH59
AIISICCCLFILFLF

ERGIC1

26

Q969X5
CCCLFILFLFLSELT

ERGIC1

31

Q969X5
LLCNLREVQCLICCL

INTS2

986

Q9H0H0
RALCAVCAPVSFLEC

LANCL3

151

Q6ZV70
CVCSLIILIVLIANC

LMTK2

51

Q8IWU2
TLCIAVSNCCFDPIV

LPAR6

276

P43657
AAVACTLLLALVACL

LRP2

6

P98164
LLCLIFTCICGIQHL

KCNT2

206

Q6UVM3
ALCVAAGVLLAICLF

NRSN2

121

Q9GZP1
CVACCRVLPSLDALL

FAM170B

206

A6NMN3
VAFVLAVACTVACCK

PAQR9

216

Q6ZVX9
LVSAILLTTLAACCC

LRRC32

636

Q14392
IICTLSAIVCCIQIF

FAM189B

186

P81408
NLGVADLCFILCCVP

GALR2

66

O43603
DLCFILCCVPFQATI

GALR2

71

O43603
ILNLAVADLCFILCC

GALR3

61

O60755
VADLCFILCCVPFQA

GALR3

66

O60755
CPAVCCLTLALTTSI

ATM

536

Q13315
CEALCLLSTAFPVCI

HTT

1026

P42858
VSCLCVNLCSPYLLL

HEATR5A

1066

Q86XA9
QVTCDLFIALDVLCC

HTR1A

106

P08908
DVLCCTSSILHLCAI

HTR1A

116

P08908
CCTASILHLCVIALD

HTR1D

121

P28221
FSCSCVVLLCTALVE

ADCY3

636

O60266
CLFCEFLTLCNIVLD

MDFI

171

Q99750
FLTLCNIVLDCATCG

MDFI

176

Q99750
LQVKVPLCACALCAT

FBXO24

456

O75426
TSCICPVLVCLCFVQ

CDH18

6

Q13634
SVLLLCILFTCFCVT

DSC1

701

Q08554
FPCCVLEVLLCALAA

GRM7

16

Q14831
DLCCSDILRSAICFP

GPR85

61

P60893
CTDIICCVFLLLAIV

SLC44A2

31

Q8IWA5
SCTDVICCVLFLLFI

SLC44A4

31

Q53GD3
CCCFLLLFLVSSVPV

FGF10

21

O15520
LTGLLVCLACLAKCV

HSD17B3

11

P37058
ALCLCLVLLAVLGCS

NIPA1

226

Q7RTP0
LCCLLTGCETFEEAL

PANK1

446

Q8TE04
LFLCCISCDRFVAVV

GPR132

131

Q9UNW8
AFCAICLKLLLCVQD

RNF186

61

Q9NXI6
ILLCQHVFCEECLCL

RNFT2

396

Q96EX2
VAGLLLLTCCFCICK

SYT2

71

Q8N9I0
VLVSGLLIFSCCFCL

SYT5

36

O00445
LAAGVLLVSCLLCAA

SYT8

56

Q8NBV8
KQPSICLCSLEDFLC

SORT1

661

Q99523
ILTVICCLLAFCIGL

SLC6A15

496

Q9H2J7
CCLLAFCIGLIFVQR

SLC6A15

501

Q9H2J7
VGFCLVFATPLCCAL

SFXN3

271

Q9BWM7
LVGFCLVFATPLCCA

SFXN1

271

Q9H9B4
QKCIVIFALVCCFAI

PLD5

66

Q8N7P1
CVFCLAILVFLINCV

TMEM132B

906

Q14DG7
ACCLACVFTNPLEVV

SLC25A34

16

Q6PIV7
IEAARIFCCNSCIAI

PTCHD1

396

Q96NR3
LLGFSICLIACCVLT

SLC2A5

346

P22732
ICLIACCVLTAALAL

SLC2A5

351

P22732
LAVCILLVCTFLVCA

PTCH2

966

Q9Y6C5
FCCLFLLPLTAMAIC

GNRHR2

121

Q96P88
LSAILAITFCGICCQ

SLC9A3

306

P48764
FVCVTLCEQTLEACL

RNASEL

431

Q05823
CQAFCLLEAAASPIL

SHOC1

591

Q5VXU9
SCCVLVFLLFAVICV

ST6GAL1

11

P15907
LTCCLCDFGLSLRLD

TGFBR2

391

P37173
LNLVCGLVCLLACFV

SSPN

201

Q14714
SVALCCALCFVIDLS

SLC6A8

446

P48029
IVLICCCCTLLTAIS

SLC12A4

156

Q9UP95
ALCLFSSVCVVCAIS

SVOPL

461

Q8N434
EITQGLCFPAFCILC

PIGW

21

Q7Z7B1
CTLVFLCLSCNPLAS

SREBF1

491

P36956
CLTAVIVCCIDAFVV

CMTM1

116

Q8IZ96
LAFICEEVVSQCTLC

CMTM6

51

Q9NX76
AALTFCLPCALCQMA

CNFN

91

Q9BYD5
LTCIFLLISGSCELC

TLR8

11

Q9NR97
RSLVLVCVLAALCFA

TMEM64

121

Q6YI46
VCVLAALCFASLALV

TMEM64

126

Q6YI46
SVLLCFDIIEGLCCV

TPRA1

246

Q86W33
NLICETDRSLLCFLC

TRIM77

101

I1YAP6
LICCLLTCLLVDCFS

PP632

71

Q6XCG6
PLCVCLLLTCGFAEA

UGT1A10

11

Q9HAW8
FVLSIIITLCCVFNC

TMIE

66

Q8NEW7
VLRCVCFFCSKLLVD

POLR2A

106

P24928
LLIATTCLREHSCCF

WDFY4

221

Q6ZS81
PLCVCLLLTCGFAEA

UGT1A9

11

O60656
LFCVKDLEILCTQCS

TRIM60

106

Q495X7
LFPLCFTICISCIAV

TAS1R2

636

Q8TE23
VAVCCICFFVILPLN

TM9SF3

396

Q9HD45
TLGLCLCAVLCCFLV

TNFRSF13B

166

O14836
CRLLAAACICLLTFV

SLC7A6

166

Q92536
LEAFLSRLCCTCEAA

ZFYVE27

156

Q5T4F4
CLACLLKLICQFAVD

USP34

1521

Q70CQ2
LVCVTTAIFLVIQCC

UGT2A1

496

P0DTE4
LCCVVLCLLGANTVD

TRBV19

6

A0A075B6N1
VCVTTAIFLVIQCCL

UGT2A2

506

P0DTE5
VLTLNIVAFVIVCCC

TSHR

586

P16473