Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionDNA-binding transcription activator activity, RNA polymerase II-specific

FOXO1 HOXA10 NANOGP8 HOXC10 EGR2 NANOG NR4A3 NR4A1 MEF2D FOXF2

3.53e-055607310GO:0001228
GeneOntologyMolecularFunctionDNA-binding transcription activator activity

FOXO1 HOXA10 NANOGP8 HOXC10 EGR2 NANOG NR4A3 NR4A1 MEF2D FOXF2

3.86e-055667310GO:0001216
GeneOntologyMolecularFunctionRNA polymerase II sequence-specific DNA-binding transcription factor recruiting activity

NANOGP8 NANOG

7.87e-054732GO:0001010
GeneOntologyMolecularFunctiontranscription factor binding

FOXO1 NANOGP8 EGR2 BCAS3 NANOG NR4A3 UBA3 NR4A1 MEF2D FOXF2

3.97e-047537310GO:0008134
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

FOXO1 HOXA10 NANOGP8 RPS6KA4 HOXC10 EGR2 CES1 BCAS3 NANOG NR4A3 NR4A1 PCBP1 NIPBL MEF2D NR2F1 FOXF2

2.24e-0513907316GO:0045944
GeneOntologyCellularComponentchromatin

FOXO1 HOXA10 FANCB NANOGP8 HOXC10 INCENP EGR2 BCAS3 NANOG SUPT16H SMARCC2 NR4A3 NR4A1 NIPBL MEF2D FOXF2

4.88e-0514807416GO:0000785
DomainSUZ

ARPP21 R3HDM2 R3HDM1

2.29e-074733IPR024771
DomainSUZ

ARPP21 R3HDM2 R3HDM1

2.29e-074733PS51673
DomainR3H

ARPP21 R3HDM2 R3HDM1

4.73e-069733SM00393
DomainR3H

ARPP21 R3HDM2 R3HDM1

9.24e-0611733PS51061
DomainR3H

ARPP21 R3HDM2 R3HDM1

9.24e-0611733PF01424
Domain-

ARPP21 R3HDM2 R3HDM1

9.24e-06117333.30.1370.50
DomainR3H_dom

ARPP21 R3HDM2 R3HDM1

9.24e-0611733IPR001374
DomainSUZ

ARPP21 R3HDM1

4.51e-053732PF12752
DomainNuc_orph_rcpt

NR4A3 NR4A1

4.51e-053732IPR003070
Domainzf-C4

NR4A3 NR4A1 NR2F1

7.71e-0446733PF00105
DomainZnf_hrmn_rcpt

NR4A3 NR4A1 NR2F1

7.71e-0446733IPR001628
DomainNuclear_hrmn_rcpt

NR4A3 NR4A1 NR2F1

7.71e-0446733IPR001723
DomainNUCLEAR_REC_DBD_2

NR4A3 NR4A1 NR2F1

7.71e-0446733PS51030
DomainNUCLEAR_REC_DBD_1

NR4A3 NR4A1 NR2F1

7.71e-0446733PS00031
DomainZnF_C4

NR4A3 NR4A1 NR2F1

7.71e-0446733SM00399
Domain-

NR4A3 NR4A1 NR2F1

8.21e-04477331.10.565.10
DomainHOLI

NR4A3 NR4A1 NR2F1

8.73e-0448733SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR4A3 NR4A1 NR2F1

8.73e-0448733IPR000536
DomainHormone_recep

NR4A3 NR4A1 NR2F1

8.73e-0448733PF00104
DomainDynein_heavy_chain_D4_dom

DNAH3 DYNC1H1

1.33e-0314732IPR024317
DomainDynein_HC_stalk

DNAH3 DYNC1H1

1.33e-0314732IPR024743
DomainDynein_heavy_dom-2

DNAH3 DYNC1H1

1.33e-0314732IPR013602
DomainDHC_N2

DNAH3 DYNC1H1

1.33e-0314732PF08393
DomainMT

DNAH3 DYNC1H1

1.33e-0314732PF12777
DomainAAA_8

DNAH3 DYNC1H1

1.33e-0314732PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DYNC1H1

1.33e-0314732IPR011704
DomainAAA_5

DNAH3 DYNC1H1

1.33e-0314732PF07728
Domain-

NR4A3 NR4A1 NR2F1

1.44e-03577333.30.50.10
DomainZnf_NHR/GATA

NR4A3 NR4A1 NR2F1

1.52e-0358733IPR013088
DomainDHC_fam

DNAH3 DYNC1H1

1.53e-0315732IPR026983
DomainDynein_heavy_dom

DNAH3 DYNC1H1

1.53e-0315732IPR004273
DomainDynein_heavy

DNAH3 DYNC1H1

1.53e-0315732PF03028
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

FOXO1 HOXA10 NANOGP8 HOXC10 NANOG NR4A3 NR4A1 NR2F1 FOXF2

5.08e-0926374920932939
Pubmed

Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.

FOXO1 HOXA10 SH3TC1 BCAS3 SMARCC2 ZFR MEF2D NR2F1 DYNC1H1 CYFIP2 FOXF2

1.94e-06857741125609649
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

ARHGAP32 TULP4 EGR2 ZFR TSG101 WNK1 DYNC1H1 GAB1

3.78e-0643074835044719
Pubmed

Neddylation contributes to CD4+ T cell-mediated protective immunity against blood-stage Plasmodium infection.

FOXO1 UBA3

4.47e-06274230462731
Pubmed

Neural crest patterning: autoregulatory and crest-specific elements co-operate for Krox20 transcriptional control.

EGR2 NR4A1

4.47e-06274212538520
Pubmed

The orphan nuclear receptor Nor1/Nr4a3 is a negative regulator of β-cell mass.

NR4A3 NR4A1

4.47e-06274230696767
Pubmed

Anterior migration of lateral plate mesodermal cells during embryogenesis of the pufferfish Takifugu niphobles: insight into the rostral positioning of pelvic fins.

HOXA10 HOXC10

4.47e-06274226018586
Pubmed

Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis.

NR4A3 NR4A1

4.47e-06274220411565
Pubmed

NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes.

NR4A3 NR4A1

4.47e-06274228249906
Pubmed

Molecular signatures of thyroid follicular neoplasia.

NR4A3 NR4A1

4.47e-06274220668010
Pubmed

Nur77 promotes embryo adhesion by transcriptionally regulating HOXA10 expression.

HOXA10 NR4A1

4.47e-06274231574241
Pubmed

The nuclear orphan receptor NR4A1 and NR4A3 as tumor suppressors in hematologic neoplasms.

NR4A3 NR4A1

4.47e-06274225410408
Pubmed

Deficiency of the NR4A neuron-derived orphan receptor-1 attenuates neointima formation after vascular injury.

NR4A3 NR4A1

4.47e-06274219153266
Pubmed

Functional evidence that the self-renewal gene NANOG regulates human tumor development.

NANOGP8 NANOG

4.47e-06274219415763
Pubmed

HDAC inhibition by SNDX-275 (Entinostat) restores expression of silenced leukemia-associated transcription factors Nur77 and Nor1 and of key pro-apoptotic proteins in AML.

NR4A3 NR4A1

4.47e-06274223247046
Pubmed

Nanog1 in NTERA-2 and recombinant NanogP8 from somatic cancer cells adopt multiple protein conformations and migrate at multiple M.W species.

NANOGP8 NANOG

4.47e-06274224598770
Pubmed

Differential expression of nanog1 and nanogp8 in colon cancer cells.

NANOGP8 NANOG

4.47e-06274222079639
Pubmed

Abrogation of nuclear receptors Nr4a3 and Nr4a1 leads to development of acute myeloid leukemia.

NR4A3 NR4A1

4.47e-06274217515897
Pubmed

Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice.

NR4A3 NR4A1

4.47e-06274221205929
Pubmed

Cholinergic Grb2-Associated-Binding Protein 1 Regulates Cognitive Function.

CHAT GAB1

4.47e-06274228591834
Pubmed

Perturbation of transcription factor Nur77 expression mediated by myocyte enhancer factor 2D (MEF2D) regulates dopaminergic neuron loss in response to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP).

NR4A1 MEF2D

4.47e-06274223536182
Pubmed

Expression of NANOG and NANOGP8 in a variety of undifferentiated and differentiated human cells.

NANOGP8 NANOG

4.47e-06274221136380
Pubmed

Endofin is required for HD-PTP and ESCRT-0 interdependent endosomal sorting of ubiquitinated transmembrane cargoes.

ARHGAP32 UBAP1 TSG101 WNK1

8.41e-066074434761192
Pubmed

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

NANOGP8 NANOG

1.34e-05374219447925
Pubmed

The pluripotency factor NANOG controls primitive hematopoiesis and directly regulates Tal1.

NANOGP8 NANOG

1.34e-05374230814124
Pubmed

The molecular logic of Nanog-induced self-renewal in mouse embryonic stem cells.

NANOGP8 NANOG

1.34e-05374230846691
Pubmed

Generation of germline-competent induced pluripotent stem cells.

NANOGP8 NANOG

1.34e-05374217554338
Pubmed

Multiple phases in regulation of Nanog expression during pre-implantation development.

NANOGP8 NANOG

1.34e-05374226660234
Pubmed

Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.

NANOGP8 NANOG

1.34e-05374218177668
Pubmed

Nuclear receptors of the NR4a family are not required for the development and function of follicular T helper cells.

NR4A3 NR4A1

1.34e-05374225899083
Pubmed

Expression of Nanog gene promotes NIH3T3 cell proliferation.

NANOGP8 NANOG

1.34e-05374216259959
Pubmed

A novel NK-type homeobox gene, ENK (early embryo specific NK), preferentially expressed in embryonic stem cells.

NANOGP8 NANOG

1.34e-05374212609610
Pubmed

Cutting edge: Hypoxia-induced Nanog favors the intratumoral infiltration of regulatory T cells and macrophages via direct regulation of TGF-β1.

NANOGP8 NANOG

1.34e-05374224227785
Pubmed

NR4A nuclear receptors support memory enhancement by histone deacetylase inhibitors.

NR4A3 NR4A1

1.34e-05374222996661
Pubmed

Genome-wide profiling reveals transcriptional repression of MYC as a core component of NR4A tumor suppression in acute myeloid leukemia.

NR4A3 NR4A1

1.34e-05374223552735
Pubmed

Altered NR4A Subfamily Gene Expression Level in Peripheral Blood of Parkinson's and Alzheimer's Disease Patients.

NR4A3 NR4A1

1.34e-05374227159982
Pubmed

Nanog co-regulated by Nodal/Smad2 and Oct4 is required for pluripotency in developing mouse epiblast.

NANOGP8 NANOG

1.34e-05374224929238
Pubmed

Inhibition of adipocyte differentiation by Nur77, Nurr1, and Nor1.

NR4A3 NR4A1

1.34e-05374218945812
Pubmed

Nanog and transcriptional networks in embryonic stem cell pluripotency.

NANOGP8 NANOG

1.34e-05374217211451
Pubmed

The pluripotency factor nanog promotes breast cancer tumorigenesis and metastasis.

NANOGP8 NANOG

1.34e-05374223770853
Pubmed

The stem cell pluripotency factor NANOG activates transcription with two unusually potent subdomains at its C terminus.

NANOGP8 NANOG

1.34e-05374215502159
Pubmed

The nuclear receptors NUR77, NURR1 and NOR1 in obesity and during fat loss.

NR4A3 NR4A1

1.34e-05374222143616
Pubmed

Nuclear receptors Nur77, Nurr1, and NOR-1 expressed in atherosclerotic lesion macrophages reduce lipid loading and inflammatory responses.

NR4A3 NR4A1

1.34e-05374216873729
Pubmed

Nanog variability and pluripotency regulation of embryonic stem cells--insights from a mathematical model analysis.

NANOGP8 NANOG

1.34e-05374220574542
Pubmed

lincRNAs act in the circuitry controlling pluripotency and differentiation.

NANOGP8 NANOG

1.34e-05374221874018
Pubmed

Cell signalling regulates dynamics of Nanog distribution in embryonic stem cell populations.

NANOGP8 NANOG

1.34e-05374223054952
Pubmed

Nanog-independent reprogramming to iPSCs with canonical factors.

NANOGP8 NANOG

1.34e-05374224527385
Pubmed

Aromatic residues in the C-terminal domain 2 are required for Nanog to mediate LIF-independent self-renewal of mouse embryonic stem cells.

NANOGP8 NANOG

1.34e-05374218086680
Pubmed

The orphan nuclear receptor Nur77 is a determinant of myofiber size and muscle mass in mice.

NR4A3 NR4A1

1.34e-05374225605333
Pubmed

Regulation of Nanog expression by phosphoinositide 3-kinase-dependent signaling in murine embryonic stem cells.

NANOGP8 NANOG

1.34e-05374217204467
Pubmed

CrxOS maintains the self-renewal capacity of murine embryonic stem cells.

NANOGP8 NANOG

1.34e-05374219800316
Pubmed

Chromatin decondensation and nuclear softening accompany Nanog downregulation in embryonic stem cells.

NANOGP8 NANOG

1.34e-05374223200040
Pubmed

Selenium Augments microRNA Directed Reprogramming of Fibroblasts to Cardiomyocytes via Nanog.

NANOGP8 NANOG

1.34e-05374226975336
Pubmed

Nanog suppresses cell migration by downregulating thymosin β4 and Rnd3.

NANOGP8 NANOG

1.34e-05374223329853
Pubmed

NANOG alone induces germ cells in primed epiblast in vitro by activation of enhancers.

NANOGP8 NANOG

1.34e-05374226751055
Pubmed

Epigenetic regulation of Nanog gene in embryonic stem and trophoblast stem cells.

NANOGP8 NANOG

1.34e-05374217352742
Pubmed

OCT4/SOX2-independent Nanog autorepression modulates heterogeneous Nanog gene expression in mouse ES cells.

NANOGP8 NANOG

1.34e-05374223178592
Pubmed

Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency.

NANOGP8 NANOG

1.34e-05374225005472
Pubmed

Induction of NR4A orphan nuclear receptor expression in macrophages in response to inflammatory stimuli.

NR4A3 NR4A1

1.34e-05374215964844
Pubmed

Relevance of the NR4A sub-family of nuclear orphan receptors in trophoblastic BeWo cell differentiation.

NR4A3 NR4A1

1.34e-05374228808448
Pubmed

Roles of the Nanog protein in murine F9 embryonal carcinoma cells and their endoderm-differentiated counterparts.

NANOGP8 NANOG

1.34e-05374216773043
Pubmed

Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.

NANOGP8 NANOG

1.34e-05374223665121
Pubmed

Ectopic overexpression of Nanog induces tumorigenesis in non-tumorous fibroblasts.

NANOGP8 NANOG

1.34e-05374226733157
Pubmed

mNanog possesses dorsal mesoderm-inducing ability by modulating both BMP and Activin/nodal signaling in Xenopus ectodermal cells.

NANOGP8 NANOG

1.34e-05374223071603
Pubmed

Overexpression of NANOG in human ES cells enables feeder-free growth while inducing primitive ectoderm features.

NANOGP8 NANOG

1.34e-05374216501172
Pubmed

Regulated fluctuations in nanog expression mediate cell fate decisions in embryonic stem cells.

NANOGP8 NANOG

1.34e-05374219582141
Pubmed

The NR4A receptors Nurr1 and Nur77 are increased in human placenta from women with gestational diabetes.

NR4A3 NR4A1

1.34e-05374225199433
Pubmed

NANOG induction of fetal liver kinase-1 (FLK1) transcription regulates endothelial cell proliferation and angiogenesis.

NANOGP8 NANOG

1.34e-05374221119109
Pubmed

Pluripotency factor NANOG promotes germ cell maintenance in vitro without triggering dedifferentiation of spermatogonial stem cells.

NANOGP8 NANOG

1.34e-05374232145514
Pubmed

Nanog is the gateway to the pluripotent ground state.

NANOGP8 NANOG

1.34e-05374219703398
Pubmed

Nanog safeguards pluripotency and mediates germline development.

NANOGP8 NANOG

1.34e-05374218097409
Pubmed

Nanog Fluctuations in Embryonic Stem Cells Highlight the Problem of Measurement in Cell Biology.

NANOGP8 NANOG

1.34e-05374228636920
Pubmed

Heterogeneities in Nanog Expression Drive Stable Commitment to Pluripotency in the Mouse Blastocyst.

NANOGP8 NANOG

1.34e-05374225753417
Pubmed

NR4A1 and NR4A3 restrict HSC proliferation via reciprocal regulation of C/EBPα and inflammatory signaling.

NR4A3 NR4A1

1.34e-05374229343483
Pubmed

A distinct expression pattern in mammalian testes indicates a conserved role for NANOG in spermatogenesis.

NANOGP8 NANOG

1.34e-05374220539761
Pubmed

Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genes.

NANOGP8 NANOG

1.34e-05374218584034
Pubmed

Alternative splicing produces Nanog protein variants with different capacities for self-renewal and pluripotency in embryonic stem cells.

NANOGP8 NANOG

1.34e-05374221969378
Pubmed

Regulation of insulin-like growth factor binding protein-1 promoter activity by FKHR and HOXA10 in primate endometrial cells.

FOXO1 HOXA10

1.34e-05374212493691
Pubmed

The phosphoinositide-3-kinase/Akt pathway mediates the transient increase in Nanog expression during differentiation of F9 cells.

NANOGP8 NANOG

1.34e-05374220661723
Pubmed

NANOG restores the impaired myogenic differentiation potential of skeletal myoblasts after multiple population doublings.

NANOGP8 NANOG

1.34e-05374229245050
Pubmed

Cancer vaccination drives Nanog-dependent evolution of tumor cells toward an immune-resistant and stem-like phenotype.

NANOGP8 NANOG

1.34e-05374222337995
Pubmed

The pluripotency rheostat Nanog functions as a dimer.

NANOGP8 NANOG

1.34e-05374218290762
Pubmed

Reprogramming of mouse fibroblasts into induced pluripotent stem cells with Nanog.

NANOGP8 NANOG

1.34e-05374223333380
Pubmed

NR4A nuclear receptors in immunity and atherosclerosis.

NR4A3 NR4A1

1.34e-05374224005216
Pubmed

Deficiency of the NR4A orphan nuclear receptor NOR1 decreases monocyte adhesion and atherosclerosis.

NR4A3 NR4A1

1.34e-05374220558821
Pubmed

Aggregation of embryonic stem cells induces Nanog repression and primitive endoderm differentiation.

NANOGP8 NANOG

1.34e-05374215494369
Pubmed

Structure-based discovery of NANOG variant with enhanced properties to promote self-renewal and reprogramming of pluripotent stem cells.

NANOGP8 NANOG

1.34e-05374225825768
Pubmed

Epithelial cell senescence induces pulmonary fibrosis through Nanog-mediated fibroblast activation.

NANOGP8 NANOG

1.34e-05374231891567
Pubmed

Minireview: What is Known about SUMOylation Among NR4A Family Members?

NR4A3 NR4A1

1.34e-05374234437889
Pubmed

Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog.

NANOGP8 NANOG

1.34e-05374214728807
Pubmed

Isolation and characterization of the murine Nanog gene promoter.

NANOGP8 NANOG

1.34e-05374215916719
Pubmed

Stress and glucocorticoid regulation of NR4A genes in mice.

NR4A3 NR4A1

1.34e-05374224753204
Pubmed

Nanog retrotransposed genes with functionally conserved open reading frames.

NANOGP8 NANOG

1.34e-05374216845474
Pubmed

Nanog overcomes reprogramming barriers and induces pluripotency in minimal conditions.

NANOGP8 NANOG

1.34e-05374221194951
Pubmed

Identification and regulation of a stage-specific stem cell niche enriched by Nanog-positive spermatogonial stem cells in the mouse testis.

NANOGP8 NANOG

1.34e-05374222388986
Pubmed

NANOG changes in mouse kidneys with age.

NANOGP8 NANOG

1.34e-05374216313224
Pubmed

Functional redundancy of the Nur77 and Nor-1 orphan steroid receptors in T-cell apoptosis.

NR4A3 NR4A1

1.34e-0537429155013
Pubmed

Nanog promotes transfer of pluripotency after cell fusion.

NANOGP8 NANOG

1.34e-05374216791199
Pubmed

Differential regulation of Nr4a subfamily nuclear receptors following mast cell activation.

NR4A3 NR4A1

1.34e-05374221621845
Pubmed

Effect of Nanog overexpression on the metastatic potential of a mouse melanoma cell line B16-BL6.

NANOGP8 NANOG

1.34e-05374233665763
GeneFamilyESCRT-I

UBAP1 TSG101

2.67e-0495021116
GeneFamilyNuclear hormone receptors

NR4A3 NR4A1 NR2F1

3.35e-044950371
CoexpressionGSE26495_NAIVE_VS_PD1HIGH_CD8_TCELL_UP

FOXO1 PABPC3 OBSCN HAPLN3 OXNAD1 GPRASP2

1.80e-05193746M4654
CoexpressionGSE23984_CTRL_VS_HYPOCALEMIC_VITAMIND_ANALOG_TCELL_UP

RPS6KA4 EGR2 RC3H1 SUN1 SLC13A3 GAB1

2.20e-05200746M8051
CoexpressionBUSSLINGER_GASTRIC_IMMUNE_CELLS

PCNX2 FOXO1 WWC3 TMC6 ELP1 TMEM131L OXNAD1 ZFR WNK1 PCBP1 NIPBL MEF2D DYNC1H1 CYFIP2

6.44e-0514927414M40023
CoexpressionYAGI_AML_WITH_INV_16_TRANSLOCATION

FOXO1 DNAH3 NR4A3 NR4A1 DYNC1H1 GAB1 USP19

1.61e-04411747M1047
CoexpressionGSE19941_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_UP

INCENP POLE2 SUN1 PCBP1 AHDC1

1.67e-04182745M8126
CoexpressionHADDAD_B_LYMPHOCYTE_PROGENITOR

SECISBP2L FOXO1 ARPP21 SH3TC1 TMEM131L CYFIP2

1.72e-04290746M939
CoexpressionGSE37605_FOXP3_FUSION_GFP_VS_IRES_GFP_TREG_C57BL6_UP

EGR2 OXNAD1 NR4A3 NR4A1 GAB1

1.80e-04185745M8792
CoexpressionGSE21063_CTRL_VS_ANTI_IGM_STIM_BCELL_NFATC1_KO_3H_DN

TULP4 EGR2 RC3H1 NR4A3 GPRASP2

1.99e-04189745M8275
CoexpressionGSE17974_CTRL_VS_ACT_IL4_AND_ANTI_IL12_2H_CD4_TCELL_UP

PCNX2 OXNAD1 R3HDM2 MEF2D GPRASP2

2.19e-04193745M4185
CoexpressionGSE9509_LPS_VS_LPS_AND_IL10_STIM_IL10_KO_MACROPHAGE_30MIN_DN

FOXO1 FANCB ARPP21 GAB1 CYFIP2

2.19e-04193745M6903
CoexpressionGSE16385_IL4_VS_ROSIGLITAZONE_STIM_MACROPHAGE_UP

ARHGAP32 PIGT CENPT TULP4 SUN1

2.25e-04194745M8017
CoexpressionGSE26495_NAIVE_VS_PD1LOW_CD8_TCELL_UP

FOXO1 ARHGAP32 OBSCN OXNAD1 GPRASP2

2.30e-04195745M4658
CoexpressionGSE29618_LAIV_VS_TIV_FLU_VACCINE_DAY7_MDC_UP

ARHGAP32 VGLL3 INCENP NR4A3 STK38L

2.41e-04197745M5020
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_IL4_AND_ROSIGLITAZONE_STIM_DN

RC3H1 HAPLN3 ZFR MEF2D GAB1

2.41e-04197745M7921
CoexpressionGSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP

FOXO1 WWC3 OBSCN CHAT NIPBL

2.47e-04198745M4432
CoexpressionGSE17974_0H_VS_2H_IN_VITRO_ACT_CD4_TCELL_UP

PCNX2 ARHGAP32 OXNAD1 R3HDM2 GPRASP2

2.53e-04199745M4158
CoexpressionGSE21379_WT_VS_SAP_KO_CD4_TCELL_DN

SECISBP2L FOXO1 ARPP21 RC3H1 TMEM131L

2.53e-04199745M7511
CoexpressionGSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_DN

FOXO1 TULP4 INCENP RC3H1 WNK1

2.53e-04199745M6964
CoexpressionGSE43956_WT_VS_SGK1_KO_TH17_DIFFERENTIATED_CD4_TCELL_DN

TULP4 TSG101 NR4A1 NIPBL DYNC1H1

2.59e-04200745M9628
CoexpressionGSE42021_TREG_PLN_VS_CD24HI_TREG_THYMUS_UP

EGR2 TMC6 UBA3 NR4A1 MEF2D

2.59e-04200745M9610
CoexpressionGSE17721_CTRL_VS_GARDIQUIMOD_2H_BMDC_DN

SECISBP2L TULP4 SH3TC1 TNFRSF8 FOXF2

2.59e-04200745M3779
CoexpressionGSE16522_ANTI_CD3CD28_STIM_VS_UNSTIM_MEMORY_CD8_TCELL_UP

TULP4 RC3H1 SLC13A3 NR4A1 STK38L

2.59e-04200745M3663
CoexpressionGSE40666_NAIVE_VS_EFFECTOR_CD8_TCELL_UP

TULP4 EGR2 NR4A3 MEF2D GPRASP2

2.59e-04200745M9203
CoexpressionGSE2770_UNTREATED_VS_ACT_CD4_TCELL_2H_DN

UBAP1 OXNAD1 UBA3 PCBP1 IFNLR1

2.59e-04200745M6020
CoexpressionGSE7460_CTRL_VS_TGFB_TREATED_ACT_FOXP3_MUT_TCONV_DN

HOXA10 CES1 BCAS3 NR4A3 STK38L

2.59e-04200745M5699
CoexpressionGSE20715_0H_VS_48H_OZONE_LUNG_UP

BCAS3 ELP1 TMEM131L GAB1 FOXF2

2.59e-04200745M4368
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#2_top-relative-expression-ranked_100

EGR2 NR4A3 NR4A1

5.55e-0611703gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_100_k2
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#4_top-relative-expression-ranked_200

EGR2 NR4A3 NR4A1

1.52e-0515703gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_200_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_emap-30875_k-means-cluster#1_top-relative-expression-ranked_200

EGR2 NR4A3 NR4A1

5.05e-0522703gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr epithel_200_k1
CoexpressionAtlasDevelopingKidney_e15.5_Peripheral blastema_emap-27731_k-means-cluster#1_top-relative-expression-ranked_1000

HOXC10 EGR2 POLE2 FIGN NIPBL NR2F1

6.74e-05210706gudmap_developingKidney_e15.5_Peripheral blastema_1000_k1
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

ARHGAP32 PIGT MYO10 SUPT16H UBAP1 TMEM131L R3HDM2 TSG101 NIPBL NR2F1 CYFIP2

8.10e-058317011Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_k-means-cluster#3_top-relative-expression-ranked_1000

EGR2 POLE2 NR4A3 NR4A1 GAB1

1.70e-04157705gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#4_top-relative-expression-ranked_100

EGR2 NR4A1

2.23e-047702gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100_k4
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder epithelial cells_emap-30875_top-relative-expression-ranked_1000

FANCB VGLL3 LACTB2 EGR2 POLE2 NR4A3 NR4A1 CDCP1 IFNLR1 GAB1

2.28e-047807010gudmap_developingLowerUrinaryTract_e13.5_bladder epithelial cells_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_100

EGR2 NR4A3 NR4A1 FOXF2

2.33e-0491704gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

ARHGAP32 ARPP21 EGR2 NR4A3 NR4A1 R3HDM1 NR2F1

8.89e-0915974718e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO10 VASN OBSCN FIGN NR2F1 FOXF2

6.75e-07186746888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO10 VASN OBSCN FIGN NR2F1 FOXF2

7.89e-071917461626b23a57429f835fddc052e3c57f63a4e5b8bb
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO10 VASN OBSCN FIGN NR2F1 FOXF2

7.89e-07191746716dfa7fccbd62b5f574792e68a26dc6c45511dc
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

EGR2 CES1 VASN NR4A3 NR4A1

5.33e-06151745a937e3e5a63bfeb37d2cabb3177760ec583dbf11
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_8|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

EGR2 CES1 VASN NR4A3 NR4A1

5.33e-06151745cba0939a6dd3519f6890695f5b237266ca1a7941
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRRC25 CES1 VASN PLA2G3 WNK1

5.86e-06154745dcbc6705e91ec744801b621e5d0733a78a7a90ca
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP32 ARPP21 EGR2 R3HDM2 R3HDM1

1.09e-05175745ff0789f5913c9f3c49159e40b1ec3d2ff175ec9f
ToppCellFrontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

ARHGAP32 ARPP21 EGR2 R3HDM2 R3HDM1

1.09e-0517574521f8f11a8b874d4f7c47931010a2535f2a5a3373
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Pro-B/Pre-B_transition|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

FOXO1 ARPP21 SH3TC1 GAB1 CYFIP2

1.09e-05175745f86d2d212f8314b2410d5d84ef092b0b38607ea4
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

VASN NR4A1 FIGN NR2F1 FOXF2

1.15e-05177745452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCellB_cell_maturation-CD34+_pre-plamsa|World / Lineage and Cell class

ARPP21 SH3TC1 VASN AHDC1 GAB1

1.15e-051777453ff06100deee9bee852a52078666999a9f7beaf1
ToppCellPosterior_cortex-Neuronal-Excitatory|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCNX2 ARHGAP32 ARPP21 NR4A3 R3HDM1

1.39e-0518474525ccf08a8a26d7e7827b6357f33a53aaf423577d
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 OBSCN FIGN NR2F1 FOXF2

1.54e-05188745ee151792c7ac9afe820f1a281c6dab383799f358
ToppCell10x3'2.3-week_17-19-Lymphocytic_B-B_lineage-pro_B_progenitor|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

FOXO1 ARPP21 SH3TC1 VASN GAB1

1.66e-0519174540813c397f533c2f4a6359a77757f736b6d9e07d
ToppCellAdult-Immune-T_lymphocyte-D175|Adult / Lineage, Cell type, age group and donor

PCNX2 FOXO1 TMEM131L OXNAD1 CYFIP2

1.66e-051917450b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCellBLOOD--(3)_MNP-(3)_Non_classical_monocytes|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

LRRC25 TNFRSF8 TMC6 NR4A1 CYFIP2

1.79e-05194745f80433c7dd7590ca8c49630d2cd018b63438fd92
ToppCellCOVID-19_Severe-Non-classical_Monocyte-|COVID-19_Severe / Disease condition and Cell class

LRRC25 TNFRSF8 TMC6 NR4A1 CYFIP2

1.79e-05194745d70b9039fd2fef3e4be086513b94fb7e9bc1f670
ToppCelldroplet-Marrow-nan-3m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOXO1 ARPP21 SUPT16H TMEM131L NIPBL

1.79e-051947458ef0b71fef5b84cfd04973f891215333e7035d1d
ToppCellCOVID-19_Severe-Non-classical_Monocyte|COVID-19_Severe / Disease condition and Cell class

LRRC25 TNFRSF8 TMC6 NR4A1 CYFIP2

1.79e-051947455151546812678ae85cb22224084d27b29e3c4724
ToppCellCOVID-19_Mild-Non-classical_Monocyte|COVID-19_Mild / Disease condition and Cell class

LRRC25 TNFRSF8 TMC6 NR4A1 CYFIP2

1.84e-05195745dd00facd20a661ef23fa7fd9a02ee377b8f2d1b9
ToppCell10x5'|World / Manually curated celltypes from each tissue

TMEM131L NR4A3 NR4A1 PCBP1 CYFIP2

1.84e-05195745de28b998793271c4f69ce9e183c3e62d809e9cc8
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TULP4 MYO10 ZFR DYNC1H1 CYFIP2

1.84e-051957457796ea9247f4c63762f0de8490fed08b9717fa23
ToppCellCOVID-19_Mild-Non-classical_Monocyte-|COVID-19_Mild / Disease condition and Cell class

LRRC25 TNFRSF8 TMC6 NR4A1 CYFIP2

1.84e-051957450295d9897830987eec74f51178e14fb0a83723dc
ToppCellSevere-NK|Severe / Disease group and Cell class

HOXA10 EGR2 NR4A3 NR4A1 GAB1

1.88e-0519674566130d38b67e51e2385de8a89227759fd137999c
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

FOXO1 POLE2 HAPLN3 PLCD4 WNK1

1.98e-05198745ee71543559836fd59adc0da877b2ca538cba60cb
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

VGLL3 CES1 MYO10 NR2F1 FOXF2

2.02e-05199745212e89d097753790061310373a1fafba773488b6
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

VGLL3 CES1 MYO10 NR2F1 FOXF2

2.02e-0519974514b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellParenchyma_Control_(B.)-Stromal-TX-Smooth_muscle-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

MYO10 OBSCN FIGN NR2F1 FOXF2

2.07e-052007450c648941447c738caf62f2d71e296d6cca492c8b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial|GW16 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC1 TMC6 NR4A3 NR4A1 FOXF2

2.07e-0520074525f4c051c2e869481f33c22ad54de97efac444ad
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MYO10 OBSCN FIGN NR2F1 FOXF2

2.07e-05200745522a51a284d2992d519c4669e1a48c8ebcc08c80
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

FOXO1 SH3TC1 EGR2 TMC6 CDCP1

2.07e-052007455c638c80661017c85f9390f1b398ac7728c8f001
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Mesenchymal-BMP_responsible_cell|GW10 / Sample Type, Dataset, Time_group, and Cell type.

FOXO1 SH3TC1 EGR2 TMC6 CDCP1

2.07e-05200745604a88633d4162337e394155c7346dbdef8b9f5a
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Smooth_muscle-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MYO10 OBSCN FIGN NR2F1 FOXF2

2.07e-0520074594f1fa61aa82eb9f411b2b1cb759476939ab5db7
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC1 TMC6 NR4A3 NR4A1 FOXF2

2.07e-05200745da45a85a4667965b24ba824af871157af5b4cd19
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SH3TC1 EGR2 TMC6 NR4A3 NR4A1

2.07e-0520074574ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-3|TCGA-Breast / Sample_Type by Project: Shred V9

VGLL3 EGR2 NR4A3 NR4A1

8.02e-051377443218c787a6b087f74b0804cec14b5ebb713391b7
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Rrad|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARPP21 EGR2 NR4A3 NR4A1

8.25e-05138744b3a040c5d0e1cc94d9b19155bca8700edba2d243
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCNX2 ARHGAP32 ARPP21 R3HDM1

9.47e-051437445fb5a4ea93e5cce55d427e3b4a50a979504fad3c
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(Neuron.Gad1Gad2.Ttn)|Thalamus / BrainAtlas - Mouse McCarroll V32

TNFRSF8 TSSK4 IFNLR1

1.11e-0456743cc072782b296e75e1bb11e62d280ca199b73481e
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(Neuron.Gad1Gad2.Ttn)--|Thalamus / BrainAtlas - Mouse McCarroll V32

TNFRSF8 TSSK4 IFNLR1

1.11e-04567430c137f6263626df9837e5c00fa6ba6201bfebf52
ToppCellThalamus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Ttn_(Neuron.Gad1Gad2.Ttn)-|Thalamus / BrainAtlas - Mouse McCarroll V32

TNFRSF8 TSSK4 IFNLR1

1.11e-0456743435fdc82c2c078e5f37a60de36ce80ca0c3aade8
ToppCell10x5'-bone_marrow-Lymphocytic_B-Pro-B|bone_marrow / Manually curated celltypes from each tissue

ARPP21 SH3TC1 VASN GAB1

1.26e-041547448a8c3851888ab86ca2b13ccc042cde1fef8d88f8
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_4|390C / Donor, Lineage, Cell class and subclass (all cells)

FOXO1 INCENP TNFRSF8 HAPLN3

1.26e-04154744a90c4c45685eae8d21d03479cfd5a23f6ed3ca07
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

SH3TC1 HAPLN3 NR4A3 NR4A1

1.26e-04154744874b1220337276489a89fcc9a39bc81ba6b68baf
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_2|Macrophage / Donor, Lineage, Cell class and subclass (all cells)

PABPC3 NR4A3 NR4A1 STK38L

1.36e-041577447ceae5fe00c91d4feb8c314d3a31f027c03fa56f
ToppCell356C-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CES1 MYO10 PLCD4 FOXF2

1.46e-041607440293b244c063a62819690bf22bbc2681f8d15252
ToppCell356C-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

CES1 MYO10 PLCD4 FOXF2

1.46e-041607443eaae86fa08f7651021316f8e5811bf48055591e
ToppCellPBMC-Control-Myeloid-Neutrophil-Neutrophil-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MYO10 TNFRSF8 TSSK4 GAB1

1.46e-0416074470f3637dd0bcfcef421aa114f946fff0048f192e
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

PCNX2 ARHGAP32 ARPP21 R3HDM1

1.50e-04161744ba7ce599b173cf81c8323e7c96dc3d57379f1ed6
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TNFRSF8 CHAT NMS

1.51e-04627433eec7f31de7cc24762c5b180475650676437dc76
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TNFRSF8 CHAT NMS

1.51e-0462743f5f5441f5be00ab80a7827c4af1afbe45c552c2e
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nefm-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Nefm_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

TNFRSF8 CHAT NMS

1.51e-04627436e81a37b9defa96528654bee1b23152108d9c0b7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

INCENP OXNAD1 TSSK4 CYFIP2

1.53e-04162744af9999e5fcd28ff1f401d52fd220315752c40027
ToppCellPosterior_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

ARPP21 OBSCN NR4A3 CDCP1

1.57e-04163744218b9ba099cb27aa91c6b73bf89b44895f5dddc3
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARPP21 R3HDM2 NR4A1 R3HDM1

1.57e-041637441e8ab00ecc2d2ba35aa6745c0ed38663e26312e8
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L4-L4_IT_VISp_Rspo1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARPP21 R3HDM2 NR4A1 R3HDM1

1.57e-04163744431221a41d396b09170476179590eaf8a55266d8
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-E|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SH3TC1 EGR2 NR4A3 NR4A1

1.57e-04163744a6e272e043859858084b8d4d96fa4ff9e6eca454
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PCNX2 HAPLN3 NR4A1 GAB1

1.64e-04165744a379fa981db51bec01adea7b1e55e133e15ec383
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-5|TCGA-Ovary / Sample_Type by Project: Shred V9

PCNX2 RC3H1 OBSCN USP19

1.68e-0416674432d2eaf8a5d03881bf74d680825af2d5110b082d
ToppCell343B-Lymphocytic-ILC|343B / Donor, Lineage, Cell class and subclass (all cells)

PCNX2 HOXA10 OXNAD1 UBA3

1.68e-04166744a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|Myeloid / Condition, Lineage and Cell class

EGR2 NR4A3 NR4A1 STK38L

1.76e-04168744ea465152ea31391b63c02425beafa9a4f51f6703
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ARPP21 INCENP EGR2 PLCD4

1.76e-04168744a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCellfacs-Heart-LV-18m-Myeloid|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACP7 LRRC25 INCENP SLC13A3

1.84e-041707444eaa22040e475100061475123aefa32b56481464
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACP7 LRRC25 INCENP SLC13A3

1.84e-0417074460041b2e57e958f300a5bc76851705c8baf297c2
ToppCellfacs-Heart-LV-18m-Myeloid-monocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACP7 LRRC25 INCENP SLC13A3

1.84e-04170744793dde64f5517538b66de5f461a445c4ad6dd7b3
ToppCellIIH-CD8-naive_CD4|IIH / Condition, Cell_class and T cell subcluster

PIGT TULP4 OBSCN USP19

1.97e-041737444f2843371d18af766c1892529ce286f56c956fde
ToppCellCOVID-19-Myeloid-MoAM5,_CCL3L1|COVID-19 / Condition, Lineage and Cell class

EGR2 NR4A3 NR4A1 STK38L

1.97e-04173744502f888b7684ed39f5c577eedcacf673ae81d39e
ToppCellCOPD-Myeloid-pDC|World / Disease state, Lineage and Cell class

ARPP21 NR4A3 GAB1 CYFIP2

2.01e-04174744be8227398300711ccda5ecc41ad34064bb246b19
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FOXO1 VGLL3 NR2F1 FOXF2

2.06e-041757441799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

VGLL3 PLCD4 NR2F1 FOXF2

2.15e-041777448220cc2fc0ee8764a67a3be51d75248be2453040
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VASN PLCD4 AHDC1 NR2F1

2.15e-041777447c3d46ebd7e8726be6871aa9763e281fc0ec6ac8
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

VGLL3 PLCD4 NR2F1 FOXF2

2.15e-041777447617270f49cd6b7ba66db72d20560cee985012b2
ToppCellfacs-Heart-RV-18m-Mesenchymal-valve_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VASN PLCD4 AHDC1 NR2F1

2.15e-04177744e7b1f3092e6b8d0d580f82648035f5ad12be6961
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NANOGP8 PLA2G3 PLCD4 WNK1

2.15e-04177744c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCellCOPD-Myeloid-pDC|COPD / Disease state, Lineage and Cell class

ARPP21 NR4A3 GAB1 CYFIP2

2.15e-04177744415aa023195a7f961c09529f65cdcc7bb90eaf5d
ToppCellChildren_(3_yrs)-Mesenchymal-pericyte_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO10 OBSCN FIGN NR2F1

2.20e-04178744185b44700f06ec58b3c09c80520502166c965fd6
ToppCellIPF-Myeloid-pDC|IPF / Disease state, Lineage and Cell class

ARPP21 NR4A3 GAB1 CYFIP2

2.20e-041787448d9e28492e1f157bac3308aa947fd864ca16d277
ToppCellwk_20-22-Hematologic_Lymphocytic-B-Late_pro-B|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARPP21 SH3TC1 GAB1 CYFIP2

2.20e-041787444e28a8bd5a603518bfe993712ab785308691b5ff
ToppCellB_cells-Naive_B_cells_|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

FOXO1 ARHGAP32 WWC3 CYFIP2

2.20e-0417874471ac2eca5cf13a91f86b80690748b0788392dcfc
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HAPLN3 NR4A3 NR4A1 STK38L

2.24e-0417974442f3c040f504a91cc69292d39d22b5715c12526f
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_7|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HAPLN3 NR4A3 NR4A1 STK38L

2.24e-04179744063c05753ef1b4a18bc1ebbcae62c8cd25d11070
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MYO10 VASN OBSCN FOXF2

2.24e-04179744dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellCOPD-Myeloid-pDC|Myeloid / Disease state, Lineage and Cell class

ARPP21 NR4A3 GAB1 CYFIP2

2.24e-0417974429b058c5e33fda9f0d738c074bdb67ff16b9b6d5
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA10 CES1 NR4A3 NR4A1

2.39e-0418274437547b36264090b49a193a8ef3a8d88e647f0b79
ToppCelldroplet-Heart-4Chambers-18m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CENPT HAPLN3 NR4A3 GPRASP2

2.44e-041837446c4a09c02e30e1f24dde39f8cb8c5b453826ee2e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HAPLN3 NR4A3 NR4A1 STK38L

2.44e-04183744bd78e5c2670e67b4363078e3ca5a5b7081d24b7e
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_1|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HAPLN3 NR4A3 NR4A1 STK38L

2.44e-04183744d1bf3abf42eb9d7facf775becf1338d1faadd647
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SECISBP2L ARHGAP32 FIGN CYFIP2

2.54e-041857440d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ARHGAP32 ARPP21 R3HDM2 R3HDM1

2.60e-0418674456c139e679d640ea901ead657a8e8887e0fca098
ToppCellwk_20-22-Hematologic_Lymphocytic-B-pre-B-I_cell|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ARPP21 TMEM131L GAB1 CYFIP2

2.60e-04186744d708e8f3e371c8249e8e8f7458b352af7be412e6
ToppCellIPF-Myeloid-DC_Mature|IPF / Disease state, Lineage and Cell class

TMEM131L HAPLN3 NR4A3 GAB1

2.65e-0418774463e0304a0183b69aebb0d1a4640a506a0d6fb6e9
ToppCell5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HOXA10 VASN NR4A3 NR4A1

2.65e-041877446820bfbe552ea5e62cfe699687b051a17d9fda61
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP32 FIGN CDCP1 CYFIP2

2.70e-041887444bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellwk_15-18-Hematologic_Lymphocytic-B-Late_pro-B|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

ARPP21 SH3TC1 GAB1 CYFIP2

2.70e-041887441f24bb9cac5e74323ef93770442a869a89e07cf1
ToppCellIPF-Lymphoid-T_Regulatory|Lymphoid / Disease state, Lineage and Cell class

FOXO1 TULP4 TNFRSF8 HAPLN3

2.76e-041897447a260485c2a7c743c14d048e5e480ae0a9b8e32c
ToppCell343B-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PCNX2 HOXA10 OXNAD1 UBA3

2.76e-04189744c26428871dc3261327d89cacaba6e21e004ff1f3
ToppCellIPF-Myeloid-DC_Mature|Myeloid / Disease state, Lineage and Cell class

HAPLN3 OXNAD1 NR4A3 GAB1

2.76e-0418974449e67d298d045f29136919b7d9971b6502b0efaa
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FOXO1 MYO10 NR4A1 CYFIP2

2.76e-04189744a48df46274d51e84ffb40264646de7346104efb9
ToppCell10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_II-Z|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

EGR2 PABPC3 NR4A3 NR4A1

2.81e-041907444d401b73c0e7eb38e95d0851a128bf12bb0d3a9f
DrugClopamide [636-54-4]; Up 200; 11.6uM; MCF7; HT_HG-U133A

VGLL3 TNFRSF8 TMC6 NR4A1 WNK1 MEF2D NR2F1 USP19

1.82e-071977185402_UP
DrugChloramphenicol [56-75-7]; Down 200; 12.4uM; HL60; HT_HG-U133A

DNAH3 CENPT RPS6KA4 LACTB2 TMC6 WNK1 MEF2D

2.54e-061957171837_DN
Drugdiclofenac sodium; Down 200; 10uM; PC3; HG-U133A

RPS6KA4 MYO10 SUN1 SMARCC2 SLC13A3 NIPBL CYFIP2

2.81e-06198717445_DN
DrugFluticasone propionate [80474-14-2]; Down 200; 8uM; HL60; HT_HG-U133A

DNAH3 MYO10 TMC6 NR4A3 WNK1 USP19

2.77e-051897162928_DN
DrugOzagrel hydrochloride [78712-43-3]; Up 200; 15.2uM; HL60; HT_HG-U133A

PCNX2 FOXO1 RPS6KA4 TMC6 NIPBL GAB1

3.30e-051957162942_UP
Drugfluphenazine dihydrochloride; Up 200; 10uM; MCF7; HG-U133A

TMC6 SMARCC2 CHAT ZFR SLC13A3 CYFIP2

3.39e-05196716490_UP
DrugBuflomedil hydrochloride [35543-24-9]; Up 200; 11.6uM; HL60; HT_HG-U133A

FOXO1 CENPT RPS6KA4 SUN1 CDCP1 MEF2D

3.39e-051967161338_UP
DrugNifenazone [2139-47-1]; Down 200; 13uM; MCF7; HT_HG-U133A

CENPT HOXC10 MYO10 PLA2G3 NR4A1 CYFIP2

3.59e-051987166016_DN
DrugChlorthalidone [77-36-1]; Up 200; 11.8uM; MCF7; HT_HG-U133A

HOXA10 TULP4 TMC6 UBAP1 NR2F1 GAB1

3.59e-051987166800_UP
DrugWY-14643; Down 200; 100uM; PC3; HG-U133A

FOXO1 CHAT ZFR SLC13A3 NIPBL MEF2D

3.59e-05198716481_DN
DrugAntipyrine [60-80-0]; Up 200; 21.2uM; MCF7; HT_HG-U133A

PCNX2 HOXA10 HOXC10 NR4A1 R3HDM1 GAB1

3.59e-051987161489_UP
Drugionomycin calcium salt; Down 200; 2uM; MCF7; HT_HG-U133A_EA

FOXO1 ARHGAP32 RPS6KA4 HOXC10 ELP1 NIPBL

3.59e-05198716871_DN
DrugBetonicine [515-25-3]; Down 200; 25.2uM; MCF7; HT_HG-U133A

HOXA10 SH3TC1 TNFRSF8 NR4A1 WNK1 FOXF2

3.59e-051987163642_DN
DrugFlucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; HL60; HT_HG-U133A

MYO10 TNFRSF8 ELP1 NR4A3 GAB1 CYFIP2

3.69e-051997163128_DN
DrugDrofenine hydrochloride [548-66-3]; Down 200; 11.4uM; PC3; HT_HG-U133A

SECISBP2L PCNX2 HOXA10 ARHGAP32 PIGT NIPBL

3.80e-052007167129_DN
DrugAntigen-Antibody Complex

EGR2 NR4A3 NR4A1

5.61e-0524713ctd:D000936
DrugTi 3

ARHGAP32 SUPT16H

5.73e-054712CID000448087
DrugAmphoterin

RPS6KA4 EGR2 SUPT16H TSG101 AHDC1

7.43e-05139715CID003496889
Diseasetriacylglycerol 56:10 measurement

EGR2 NR4A1

9.00e-056732EFO_0010428
Diseasecolon cancer (implicated_via_orthology)

NANOGP8 NANOG

3.27e-0411732DOID:219 (implicated_via_orthology)
Diseasefacial asymmetry measurement

MYO10 POLE2

1.00e-0319732EFO_0009751
Diseasegout

RPS6KA4 BCAS3 R3HDM2 SLC13A3

1.44e-03196734EFO_0004274

Protein segments in the cluster

PeptideGeneStartEntry
TSYPPMCTQDPKAGQ

CES1

81

P23141
TYRPFQGTMGVCPPS

CDCP1

761

Q9H5V8
IMFAGYSPAPPTCFI

POLE2

306

P56282
CDFIGPYSMNPSTPS

AHDC1

1341

Q5TGY3
KFFVTSCYPCPGPNM

BCAS3

216

Q9H6U6
SLPATGMPVYCNVTP

ARPP21

756

Q9UBL0
GMPVYCNVTPPTPQN

ARPP21

761

Q9UBL0
QSPQQSGYIMTAAPP

R3HDM1

576

Q15032
QQPSPQMPACYCAPG

R3HDM1

636

Q15032
YSMIPPAQQNGTSPS

R3HDM2

651

Q9Y2K5
CSPPQMPQQYSGVSP

R3HDM2

686

Q9Y2K5
GMYYTPPPQCVSRFV

RC3H1

611

Q5TC82
EPYPTSRYGSQCMQP

NR2F1

196

P10589
PMIPDYPGFFPSQCQ

EGR2

221

P11161
MPCIQAQYGTPAPSP

NR4A1

1

P22736
EPVAASLPYMTCPGN

ACP7

191

Q6ZNF0
PSLNSEAVYPMNCVP

FIGN

111

Q5HY92
IPYQPMPASSPVICA

PCBP1

181

Q15365
TVQYPIMLPRQPCGG

HAPLN3

221

Q96S86
CFCMLQIPSSGFPQP

NMS

16

Q5H8A3
ANATYQLPPCMPPLD

IFNLR1

141

Q8IU57
CTSYQMTPQGHRAPP

INCENP

801

Q9NQS7
PIQEANYVPMTPGTF

GAB1

466

Q13480
CPSTPDYENMFVGQP

LRRC25

236

Q8N386
CDQPLGYPMYVSPLT

PCNX2

1821

A6NKB5
CNPGPMTLQGTNTYL

LACTB2

21

Q53H82
PVQCVPYLIAMGTDP

NIPBL

2316

Q6KC79
PVICGPEENYPSLQM

NANOG

26

Q9H9S0
STYCMPQNAGDLPSP

MYO10

1071

Q9HD67
QTVVPPPMCTYQLLF

ELP1

406

O95163
SPGVPMQTPCFTLQY

RPS6KA4

561

O75676
GYLLPSPNYPTTMSC

HOXA10

6

P31260
QPCIEPPPSSIMYQA

CYFIP2

26

Q96F07
MTPNCQYRPQSVPPH

ARHGAP32

1496

A7KAX9
AVPNQRAPPSGYFMT

PABPC3

391

Q9H361
STNPFPAPYLMPCEI

FANCB

531

Q8NB91
YPVSFDCVVTGQPMP

OBSCN

5141

Q5VST9
YICGPPPMTDFFSKQ

OXNAD1

281

Q96HP4
GTMMQQTPCYSFAPP

FOXO1

396

Q12778
LNPTCAVFITMNPGY

DNAH3

1521

Q8TD57
TQPFSQPMVGSPNVY

CENPT

241

Q96BT3
QPMVGSPNVYHSLPC

CENPT

246

Q96BT3
MTCPRNVTPNSYAEP

HOXC10

1

Q9NYD6
KPNTPVLMCSVPGYD

DYNC1H1

4036

Q14204
YMPVPCQPSTCVFSS

KRTAP29-1

221

A8MX34
PFMGILPSNKVCPQY

SLC13A3

71

Q8WWT9
YGSTVPAPNFAMPVT

MEF2D

131

Q14814
IPAMCIYLQPPSGNS

OR2J3

256

O76001
MSPNPGSTYMASCPV

FOXF2

276

Q12947
MPCVQAQYSPSPPGS

NR4A3

1

Q92570
MLIGYPPFCSETPQE

STK38L

316

Q9Y2H1
FNPACLPIYQDMTQP

PLCD4

281

Q9BRC7
CNPMTVNSLPQYAEP

TMEM131L

1371

A2VDJ0
PVICGPEENYPSLQM

NANOGP8

26

Q6NSW7
MPVAVGPYGQSQPSC

ROMO1

1

P60602
APPYPNLNMIETFIC

GPRASP2

666

Q96D09
PMNFTSYIVPVCLPS

PRSS47P

181

A8MTI9
GTPPCQMGVYPTDLT

SH3TC1

71

Q8TE82
PYCMTPVSQGSPASS

SECISBP2L

641

Q93073
PSTVEMCYPPIIQSG

SUPT16H

236

Q9Y5B9
PSEPLRGPMSFYNQC

PLA2G3

476

Q9NZ20
YQPIPFSQSGNPVMS

SMARCC2

661

Q8TAQ2
PTTTEMFCCYGPVVP

CHAT

661

P28329
PYNPPICFVKPTSSM

TSG101

81

Q99816
ELYPPQVNFPMCTIA

UBA3

226

Q8TBC4
YSACPPMQNPQGTLP

TULP4

1266

Q9NRJ4
YSVSVFQPPFQPGRM

USP19

866

O94966
KMVPSNQPVGCSPSY

TSSK4

171

Q6SA08
QVPNMPSCPQAYSEL

UBAP1

371

Q9NZ09
NLPTPDFSMPYNVIC

PIGT

516

Q969N2
YRCPMGLFPTQQCPQ

TNFRSF8

46

P28908
RPNATYSVCVMPLGP

VASN

526

Q6EMK4
MIPICPVVSFTYVPS

ZFR

1

Q96KR1
SQCTPRVGGLPYNMP

TMC6

326

Q7Z403
LHMYSPPQCVPENTG

SUN1

6

O94901
FTKSMCPPQQYGFPA

WNK1

2316

Q9H4A3
SQYLPNPMAATTCPT

VGLL3

16

A8MV65
NPMAATTCPTAYYQP

VGLL3

21

A8MV65
TQTSPPYPEPCCMGI

WWC3

826

Q9ULE0