Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
MousePheno	increased ornithine level	OAT BCS1L SLC3A1	4.95e-06	5	112	3	MP:0030647
MousePheno	abnormal ornithine level	OAT BCS1L SLC3A1	1.71e-05	7	112	3	MP:0030646
MousePheno	increased circulating ornithine level	OAT BCS1L	6.36e-05	2	112	2	MP:0030650
MousePheno	abnormal arginine level	OAT BCS1L SLC3A1	7.88e-05	11	112	3	MP:0030663
Domain	Glycoside_hydrolase_SF	GLB1L3 NAGLU MYORG SLC3A1 GUSB	5.41e-05	53	144	5	IPR017853
Domain	FN3	INSRR MYOM3 DSCAML1 IFNLR1 ANOS1 CSF2RB CNTN5 MYOM2	1.58e-04	199	144	8	PS50853
Domain	Glyco_hydro_catalytic_dom	DPEP1 GLB1L3 SLC3A1 GUSB	2.04e-04	38	144	4	IPR013781
Domain	FN3_dom	INSRR MYOM3 DSCAML1 IFNLR1 ANOS1 CSF2RB CNTN5 MYOM2	2.20e-04	209	144	8	IPR003961
Domain	fn3	INSRR MYOM3 DSCAML1 ANOS1 CSF2RB CNTN5 MYOM2	2.64e-04	162	144	7	PF00041
Domain	DDT	BAZ2B BAZ2A	3.51e-04	4	144	2	PF02791
Domain	DDT	BAZ2B BAZ2A	5.81e-04	5	144	2	SM00571
Domain	DDT_dom	BAZ2B BAZ2A	5.81e-04	5	144	2	IPR018501
Domain	WHIM2_dom	BAZ2B BAZ2A	5.81e-04	5	144	2	IPR028941
Domain	WSD	BAZ2B BAZ2A	5.81e-04	5	144	2	PF15613
Domain	FN3	INSRR MYOM3 DSCAML1 ANOS1 CSF2RB CNTN5 MYOM2	5.87e-04	185	144	7	SM00060
Domain	NUDIX_BOX	TRPM2 NUDT11 NUDT10	8.07e-04	24	144	3	PS00893
Domain	DDT	BAZ2B BAZ2A	8.68e-04	6	144	2	PS50827
Domain	NUDIX	TRPM2 NUDT11 NUDT10	1.02e-03	26	144	3	PS51462
Domain	APC_su10/DOC_dom	HECTD3 CUL7	1.21e-03	7	144	2	IPR004939
Domain	RPEL	PHACTR3 PHACTR1	1.21e-03	7	144	2	PS51073
Domain	RPEL	PHACTR3 PHACTR1	1.21e-03	7	144	2	SM00707
Domain	DOC	HECTD3 CUL7	1.21e-03	7	144	2	PS51284
Domain	ANAPC10	HECTD3 CUL7	1.21e-03	7	144	2	PF03256
Domain	RPEL	PHACTR3 PHACTR1	1.21e-03	7	144	2	PF02755
Domain	RPEL_repeat	PHACTR3 PHACTR1	1.21e-03	7	144	2	IPR004018
Domain	APC10	HECTD3 CUL7	1.21e-03	7	144	2	SM01337
Domain	-	TRPM2 NUDT11 NUDT10	1.28e-03	28	144	3	3.90.79.10
Domain	NUDIX_hydrolase_dom-like	TRPM2 NUDT11 NUDT10	1.28e-03	28	144	3	IPR015797
Domain	NUDIX_hydrolase_dom	TRPM2 NUDT11 NUDT10	1.42e-03	29	144	3	IPR000086
Domain	-	BAZ2B BAZ2A	1.60e-03	8	144	2	3.30.890.10
Domain	-	DNHD1 NUGGC ABCA2 NOA1 RNF213 BCS1L OPA1 ARL4D DNAH12 ABCA6 SUPV3L1 YLPM1 SMG9 NLRC5	1.90e-03	746	144	14	3.40.50.300
Domain	zf-C2H2_11	ZNF354A ZNF354B	2.05e-03	9	144	2	PF16622
Domain	P-loop_NTPase	DNHD1 NUGGC ABCA2 NOA1 RNF213 BCS1L OPA1 ARL4D DNAH12 ABCA6 STARD9 SUPV3L1 YLPM1 SMG9 NLRC5	2.33e-03	848	144	15	IPR027417
Domain	-	HECTD3 GLB1L3 CUL7 GUSB	2.44e-03	73	144	4	2.60.120.260
Domain	-	GLB1L3 SLC3A1 GUSB	2.45e-03	35	144	3	3.20.20.80
Domain	MBD	BAZ2B BAZ2A	3.10e-03	11	144	2	SM00391
Domain	MBD	BAZ2B BAZ2A	3.10e-03	11	144	2	PS50982
Domain	Methyl_CpG_DNA-bd	BAZ2B BAZ2A	3.10e-03	11	144	2	IPR001739
Domain	MBD	BAZ2B BAZ2A	3.10e-03	11	144	2	PF01429
Domain	DNA-bd_dom	BAZ2B BAZ2A	3.10e-03	11	144	2	IPR016177
Domain	ABC_A	ABCA2 ABCA6	3.70e-03	12	144	2	IPR026082
Domain	NUDIX_hydrolase_CS	NUDT11 NUDT10	3.70e-03	12	144	2	IPR020084
Domain	SAM_2	STARD13 PPFIBP2 INPPL1	4.42e-03	43	144	3	PF07647
Domain	BTB-kelch_protein	KLHL31 KLHL21 KLHL34	4.42e-03	43	144	3	IPR017096
Domain	Dynein_heavy_dom-2	DNHD1 DNAH12	5.06e-03	14	144	2	IPR013602
Domain	DHC_N2	DNHD1 DNAH12	5.06e-03	14	144	2	PF08393
Domain	AAA	ABCA2 RNF213 BCS1L DNAH12 ABCA6	5.19e-03	144	144	5	SM00382
Domain	AAA+_ATPase	ABCA2 RNF213 BCS1L DNAH12 ABCA6	5.19e-03	144	144	5	IPR003593
Domain	DHC_fam	DNHD1 DNAH12	5.80e-03	15	144	2	IPR026983
Domain	Dynamin_GTPase	NUGGC OPA1	5.80e-03	15	144	2	IPR001401
Domain	START_lipid-bd_dom	STARD13 STARD9	5.80e-03	15	144	2	IPR002913
Domain	Dynamin_SF	NUGGC OPA1	5.80e-03	15	144	2	IPR022812
Domain	Dynein_heavy	DNHD1 DNAH12	5.80e-03	15	144	2	PF03028
Domain	START	STARD13 STARD9	5.80e-03	15	144	2	PF01852
Domain	Dynamin_N	NUGGC OPA1	5.80e-03	15	144	2	PF00350
Domain	Dynein_heavy_dom	DNHD1 DNAH12	5.80e-03	15	144	2	IPR004273
Domain	START	STARD13 STARD9	5.80e-03	15	144	2	PS50848
Domain	Galactose-bd-like	HECTD3 GLB1L3 CUL7 GUSB	6.05e-03	94	144	4	IPR008979
Domain	SAM_DOMAIN	STARD13 PPFIBP2 INPPL1 BFAR	6.27e-03	95	144	4	PS50105
Domain	KRAB	ZNF354A ZNF337 ZNF354B ZNF785 ZNF41 ZNF436 ZNF558 ZNF778	6.65e-03	358	144	8	PS50805
Domain	KRAB	ZNF354A ZNF337 ZNF354B ZNF785 ZNF41 ZNF436 ZNF558 ZNF778	6.65e-03	358	144	8	PF01352
Domain	SAM	STARD13 PPFIBP2 INPPL1 BFAR	6.75e-03	97	144	4	IPR001660
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SEMA6B ABCA2 MAN2B1 INPPL1 TSNARE1 NLRX1 NAGLU MYOM3 IFNLR1 MYORG C2CD3 SND1 ADAMTS7 KLHL21 A4GALT NLRC5	1.62e-05	1105	145	16	35748872
Pubmed	PCSK9 Induces CD36 Degradation and Affects Long-Chain Fatty Acid Uptake and Triglyceride Metabolism in Adipocytes and in Mouse Liver.	CD36 PCSK9	1.73e-05	2	145	2	26494228
Pubmed	Hepatic cholesterol synthesis and lipoprotein levels impaired by dietary fructose and saturated fatty acids in mice: Insight on PCSK9 and CD36.	CD36 PCSK9	1.73e-05	2	145	2	32862122
Pubmed	Paralogous murine Nudt10 and Nudt11 genes have differential expression patterns but encode identical proteins that are physiologically competent diphosphoinositol polyphosphate phosphohydrolases.	NUDT11 NUDT10	1.73e-05	2	145	2	12689335
Pubmed	Immunocytochemistry for MUC4 and MUC16 is a useful adjunct in the diagnosis of pancreatic adenocarcinoma on fine-needle aspiration cytology.	MUC16 MUC4	1.73e-05	2	145	2	23544943
Pubmed	Long noncoding RNA FER1L4 regulates rheumatoid arthritis via targeting NLRC5.	FER1L4 NLRC5	1.73e-05	2	145	2	31694750
Pubmed	Class switching and meiotic defects in mice lacking the E3 ubiquitin ligase RNF8.	RNF8 TP53BP1	1.73e-05	2	145	2	20385748
Pubmed	An adjacent pair of human NUDT genes on chromosome X are preferentially expressed in testis and encode two new isoforms of diphosphoinositol polyphosphate phosphohydrolase.	NUDT11 NUDT10	1.73e-05	2	145	2	12105228
Pubmed	RNF8-dependent and RNF8-independent regulation of 53BP1 in response to DNA damage.	RNF8 TP53BP1	1.73e-05	2	145	2	18337245
Pubmed	RNF8 regulates active epigenetic modifications and escape gene activation from inactive sex chromosomes in post-meiotic spermatids.	RNF8 TP53BP1	1.73e-05	2	145	2	23249736
Pubmed	Characterization of the mouse Kid1 gene and identification of a highly related gene, Kid2.	ZNF354A ZNF354B	1.73e-05	2	145	2	10564808
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SYNM BAZ2B RNF8 CILK1 RNF213 CUL7 MYORG C2CD5 PHF2 ZNF436	4.48e-05	493	145	10	15368895
Pubmed	Regulation of 53BP1 protein stability by RNF8 and RNF168 is important for efficient DNA double-strand break repair.	RNF8 TP53BP1	5.16e-05	3	145	2	25337968
Pubmed	Microbial products alter the expression of membrane-associated mucin and antimicrobial peptides in a three-dimensional human endocervical epithelial cell model.	MUC16 MUC4	5.16e-05	3	145	2	23053434
Pubmed	CRIF1 enhances p53 activity via the chromatin remodeler SNF5 in the HCT116 colon cancer cell lines.	GADD45GIP1 SMARCB1	5.16e-05	3	145	2	28235567
Pubmed	Integrative analysis of the cancer genome atlas and cancer cell lines encyclopedia large-scale genomic databases: MUC4/MUC16/MUC20 signature is associated with poor survival in human carcinomas.	MUC16 MUC4	5.16e-05	3	145	2	30236127
Pubmed	Lysosomal dysfunction results in altered energy balance.	NAGLU GUSB	5.16e-05	3	145	2	17911106
Pubmed	Functional Consequences of Differential O-glycosylation of MUC1, MUC4, and MUC16 (Downstream Effects on Signaling).	MUC16 MUC4	5.16e-05	3	145	2	27483328
Pubmed	MicroRNA-200c modulates the expression of MUC4 and MUC16 by directly targeting their coding sequences in human pancreatic cancer.	MUC16 MUC4	5.16e-05	3	145	2	24204560
Pubmed	Expression of the transmembrane mucins, MUC1, MUC4 and MUC16, in normal endometrium and in endometriosis.	MUC16 MUC4	5.16e-05	3	145	2	24939955
Pubmed	Distinct versus overlapping functions of MDC1 and 53BP1 in DNA damage response and tumorigenesis.	RNF8 TP53BP1	5.16e-05	3	145	2	18504301
Pubmed	Regulation of membrane-associated mucins in the human corneal epithelial cells by dexamethasone.	MUC16 MUC4	5.16e-05	3	145	2	17592322
Pubmed	PCSK9 (Proprotein Convertase Subtilisin/Kexin 9) Enhances Platelet Activation, Thrombosis, and Myocardial Infarct Expansion by Binding to Platelet CD36.	CD36 PCSK9	5.16e-05	3	145	2	32988222
Pubmed	Structural basis of molecular recognition of helical histone H3 tail by PHD finger domains.	BAZ2B BAZ2A	5.16e-05	3	145	2	28341809
Pubmed	Cloning and characterisation of hAps1 and hAps2, human diadenosine polyphosphate-metabolising Nudix hydrolases.	NUDT11 NUDT10	5.16e-05	3	145	2	12121577
Pubmed	The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination.	RNF8 TP53BP1	5.16e-05	3	145	2	20080757
Pubmed	Genome-wide bidirectional CRISPR screens identify mucins as host factors modulating SARS-CoV-2 infection.	MUC16 MUC4	5.16e-05	3	145	2	35879412
Pubmed	Give me a break, but not in mitosis: the mitotic DNA damage response marks DNA double-strand breaks with early signaling events.	RNF8 TP53BP1	5.16e-05	3	145	2	21412056
Pubmed	TGFβ attenuates cartilage extracellular matrix degradation via enhancing FBXO6-mediated MMP14 ubiquitination.	ABCA2 MAN2B1 NAGLU B3GNT3 MYORG CHPF2	6.79e-05	164	145	6	32409323
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	HECTD3 RNF213 CUL7 OPA1 GADD45GIP1 C2CD5 NUFIP1 PHF2 BAZ2A KLHL21 NT5DC2 PANK4 NFRKB SMARCB1 CHPF2	7.00e-05	1116	145	15	31753913
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PLK2 ABCA2 PDE9A STAG1 SYNM ADAM9 USP25 OAT DSCAML1 ZNF785 NUFIP1 P4HTM SUPV3L1 YLPM1 ZNF558 SH3BP5	9.70e-05	1285	145	16	35914814
Pubmed	Accumulation of Pax2 transactivation domain interaction protein (PTIP) at sites of DNA breaks via RNF8-dependent pathway is required for cell survival after DNA damage.	RNF8 TP53BP1	1.03e-04	4	145	2	19124460
Pubmed	PTIP regulates 53BP1 and SMC1 at the DNA damage sites.	RNF8 TP53BP1	1.03e-04	4	145	2	19414588
Pubmed	RNF8 regulates assembly of RAD51 at DNA double-strand breaks in the absence of BRCA1 and 53BP1.	RNF8 TP53BP1	1.03e-04	4	145	2	22865450
Pubmed	TRPV4 activation in human corneal epithelial cells promotes membrane mucin production.	MUC16 MUC4	1.03e-04	4	145	2	39024979
Pubmed	ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport.	ABCA2 ABCA6	1.03e-04	4	145	2	10639163
Pubmed	Nudix hydrolases that degrade dinucleoside and diphosphoinositol polyphosphates also have 5-phosphoribosyl 1-pyrophosphate (PRPP) pyrophosphatase activity that generates the glycolytic activator ribose 1,5-bisphosphate.	NUDT11 NUDT10	1.03e-04	4	145	2	12370170
Pubmed	A viral E3 ligase targets RNF8 and RNF168 to control histone ubiquitination and DNA damage responses.	RNF8 TP53BP1	1.03e-04	4	145	2	20075863
Pubmed	Interaction of human papillomavirus type 16 L2 with cellular proteins: identification of novel nuclear body-associated proteins.	MAN2B1 GADD45GIP1	1.03e-04	4	145	2	12482659
Pubmed	Chromosomal localization of the genes for five zinc finger proteins expressed in mouse lens.	ZNF354A ZNF436 GABRA1	1.03e-04	22	145	3	7590745
Pubmed	Acetylation-Mimic Mutation of TRIM28-Lys304 to Gln Attenuates the Interaction with KRAB-Zinc-Finger Proteins and Affects Gene Expression in Leukemic K562 Cells.	ZNF354A ZNF354B ZNF785 ZNF41 ZNF558 ZNF778	1.17e-04	181	145	6	37372979
Pubmed	A mitochondrial protein compendium elucidates complex I disease biology.	ACLY NOA1 NLRX1 MRPL54 OAT MTFP1 BCS1L OPA1 GADD45GIP1 HARS2 SND1 SUPV3L1 SLC22A4 SLC25A28	1.30e-04	1047	145	14	18614015
Pubmed	Genetic variants in nuclear-encoded mitochondrial genes influence AIDS progression.	ACLY NOA1 NLRX1 MRPL54 OAT MTFP1 BCS1L OPA1 HARS2 SND1 SUPV3L1 SLC22A4 SLC25A28	1.42e-04	926	145	13	20877624
Pubmed	Myomesin 3, a novel structural component of the M-band in striated muscle.	MYOM3 MYOM2	1.71e-04	5	145	2	18177667
Pubmed	Ubiquitinated CD36 sustains insulin-stimulated Akt activation by stabilizing insulin receptor substrate 1 in myotubes.	CUL7 CD36	1.71e-04	5	145	2	29269414
Pubmed	Single-cell transcriptomics identifies potential cells of origin of MYC rhabdoid tumors.	DPPA3 SMARCB1	1.71e-04	5	145	2	35318328
Pubmed	Common sequence variants on 2p15 and Xp11.22 confer susceptibility to prostate cancer.	NUDT11 NUDT10	1.71e-04	5	145	2	18264098
Pubmed	A novel family of bromodomain genes.	BAZ2B BAZ2A	1.71e-04	5	145	2	10662543
Pubmed	Genome-wide association study of coronary and aortic calcification implicates risk loci for coronary artery disease and myocardial infarction.	ADAMTS7 PHACTR1	1.71e-04	5	145	2	23561647
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	SYNM NOA1 MRPL54 RNF213 OAT CUL7 BCS1L OPA1 GADD45GIP1 PTPN2 HARS2 SND1 BAZ2A NT5DC2 SUPV3L1 PANK4 SEC23A	1.74e-04	1496	145	17	32877691
Pubmed	Functional proteomics mapping of a human signaling pathway.	STARD13 MAN2B1 STAG1 USP25 CILK1 ZNF106 MTMR11 ZNF41 PHACTR3 YLPM1	1.98e-04	591	145	10	15231748
Pubmed	A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.	BFAR ANOS1 NUDT11 NUDT10 NLRC5 ARHGAP27	2.30e-04	205	145	6	12040188
Pubmed	A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome.	NOA1 MRPL54 OAT GADD45GIP1 HARS2 SUPV3L1	2.42e-04	207	145	6	20186120
Pubmed	The proximity ligation assay reveals that at DNA double-strand breaks WRAP53β associates with γH2AX and controls interactions between RNF8 and MDC1.	RNF8 TP53BP1	2.56e-04	6	145	2	26734725
Pubmed	RNF8 ubiquitylates histones at DNA double-strand breaks and promotes assembly of repair proteins.	RNF8 TP53BP1	2.56e-04	6	145	2	18001824
Pubmed	Regulation of MHC Class I Expression in Lung Epithelial Cells during Inflammation.	IFNLR1 NLRC5	2.56e-04	6	145	2	35173036
Pubmed	In vivo CRISPR screening identifies BAZ2 chromatin remodelers as druggable regulators of mammalian liver regeneration.	BAZ2B BAZ2A	2.56e-04	6	145	2	35090595
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ADAM9 CAMTA2 ZSWIM6 SPATA2 OPA1 BAZ2A STARD9 CHPF2	3.25e-04	407	145	8	12693553
Pubmed	Phactrs 1-4: A family of protein phosphatase 1 and actin regulatory proteins.	PHACTR3 PHACTR1	3.58e-04	7	145	2	15107502
Pubmed	RNF8 transduces the DNA-damage signal via histone ubiquitylation and checkpoint protein assembly.	RNF8 TP53BP1	3.58e-04	7	145	2	18001825
Pubmed	Different expression patterns of Phactr family members in normal and injured mouse brain.	PHACTR3 PHACTR1	3.58e-04	7	145	2	22766235
Pubmed	Characterization of the Cardiac Overexpression of HSPB2 Reveals Mitochondrial and Myogenic Roles Supported by a Cardiac HspB2 Interactome.	MTFP1 OPA1 NT5DC2 CD36 MYOM2	3.90e-04	147	145	5	26465331
Pubmed	CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle function.	MYOM3 MYOM2	4.75e-04	8	145	2	20215401
Pubmed	IFN-λ Enhances Constitutive Expression of MHC Class I Molecules on Thymic Epithelial Cells.	IFNLR1 NLRC5	4.75e-04	8	145	2	32690660
Pubmed	Primary structure and chromosomal localization of human and mouse rod photoreceptor cGMP-gated cation channel.	GUSB CNGA1	4.75e-04	8	145	2	1372902
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	ABCA2 MAN2B1 ACLY ADAM9 TMEM161B NAGLU RNF213 MYORG P4HTM GUSB A4GALT DPY19L4 CHPF2 PCSK9	5.20e-04	1201	145	14	35696571
Pubmed	Chromosome mapping of the rod photoreceptor cGMP phosphodiesterase beta-subunit gene in mouse and human: tight linkage to the Huntington disease region (4p16.3).	GUSB CNGA1	6.10e-04	9	145	2	1315306
Pubmed	BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.	RNF8 TP53BP1	6.10e-04	9	145	2	30704900
Pubmed	Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks.	RNF8 TP53BP1	6.10e-04	9	145	2	20016603
Pubmed	Update on the Kelch-like (KLHL) gene family.	KLHL31 KLHL21 KLHL34	6.74e-04	41	145	3	23676014
Pubmed	Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease.	ADAMTS7 PCSK9 PHACTR1	8.86e-04	45	145	3	21378990
Pubmed	Multiple newly identified loci associated with prostate cancer susceptibility.	NUDT11 NUDT10	9.26e-04	11	145	2	18264097
Pubmed	53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair.	RNF8 TP53BP1	9.26e-04	11	145	2	20081839
Pubmed	Quantitative high-confidence human mitochondrial proteome and its dynamics in cellular context.	NOA1 NLRX1 MRPL54 OAT MTFP1 BCS1L OPA1 GADD45GIP1 HARS2 NT5DC2 SUPV3L1 SLC22A4 SLC25A28	9.76e-04	1136	145	13	34800366
Pubmed	Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition.	AMHR2 HECTD3 INSRR CILK1 FBXO4 NFRKB KLHL34	9.90e-04	372	145	7	22939624
Pubmed	Characterization of the Cullin7 E3 ubiquitin ligase--heterodimerization of cullin substrate receptors as a novel mechanism to regulate cullin E3 ligase activity.	CUL7 FBXO4	1.11e-03	12	145	2	21946088
Pubmed	TRIM28 functions as a negative regulator of aggresome formation.	ACLY SND1	1.11e-03	12	145	2	33783327
Pubmed	The Oncogenic PRL Protein Causes Acid Addiction of Cells by Stimulating Lysosomal Exocytosis.	CADM4 SMARCB1 MYOM2	1.14e-03	49	145	3	32918875
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	NUGGC F2 OPA1 ZNF106 DNAH12 SMARCB1 MYOM2 MUC4	1.19e-03	497	145	8	36774506
Pubmed	FAAP100 is required for the resolution of transcription-replication conflicts in primordial germ cells.	DPPA3 TP53BP1	1.31e-03	13	145	2	37580696
Pubmed	The Ubiquitin E3/E4 Ligase UBE4A Adjusts Protein Ubiquitylation and Accumulation at Sites of DNA Damage, Facilitating Double-Strand Break Repair.	RNF8 TP53BP1	1.31e-03	13	145	2	29499138
Pubmed	Testis determination requires insulin receptor family function in mice.	AMHR2 INSRR	1.31e-03	13	145	2	14628051
Pubmed	MCM8 interacts with DDX5 to promote R-loop resolution.	DPPA3 TP53BP1	1.31e-03	13	145	2	38858601
Pubmed	DNA repair protein FANCD2 has both ubiquitination-dependent and ubiquitination-independent functions during germ cell development.	DPPA3 TP53BP1	1.31e-03	13	145	2	36642183
Pubmed	Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags.	STARD13 RNF8 MTFP1 F2 BCS1L A4GALT BHMT2 SMARCB1	1.40e-03	510	145	8	16712791
Pubmed	The protein network surrounding the human telomere repeat binding factors TRF1, TRF2, and POT1.	ACLY LLGL1 NT5DC2 NFRKB MYOM2	1.46e-03	197	145	5	20811636
Pubmed	Mutant p53 interactome identifies nardilysin as a p53R273H-specific binding partner that promotes invasion.	CUL7 TP53BP1	1.52e-03	14	145	2	22653443
Pubmed	FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.	RNF8 TP53BP1	1.52e-03	14	145	2	26123487
Pubmed	Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.	NLRX1 NLRC5	1.52e-03	14	145	2	26320999
Pubmed	Tankyrases inhibit innate antiviral response by PARylating VISA/MAVS and priming it for RNF146-mediated ubiquitination and degradation.	NLRX1 OPA1	1.52e-03	14	145	2	35733260
Pubmed	Structural basis for SMAC-mediated antagonism of caspase inhibition by the giant ubiquitin ligase BIRC6.	HARS2 NT5DC2 SUPV3L1	1.59e-03	55	145	3	36758106
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	UTP6 MRPL54 RIOX1 OPA1 ZNF106 BAZ2A YLPM1	1.73e-03	410	145	7	26949251
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	UTP6 ACLY OAT CUL7 SND1 BAZ2A YLPM1 SEC23A TP53BP1	1.74e-03	653	145	9	22586326
Pubmed	Validation of genome-wide prostate cancer associations in men of African descent.	NUDT11 NUDT10	1.75e-03	15	145	2	21071540
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	UTP6 MAN2B1 ZNF337 GADD45GIP1 GUSB SUPV3L1 NUDT10	1.95e-03	419	145	7	33001583
Pubmed	Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants.	PCSK9 PHACTR1	1.99e-03	16	145	2	19198609
Pubmed	Transcription-replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability.	DPPA3 TP53BP1	2.25e-03	17	145	2	35969748
Pubmed	A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease.	ADAMTS7 PHACTR1	2.25e-03	17	145	2	21378988
Pubmed	A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.	NOA1 NLRX1 MTFP1 BCS1L GADD45GIP1 HARS2 LLGL1 GUSB NT5DC2	2.42e-03	686	145	9	28380382
Pubmed	Variability in Streptavidin-Sepharose Matrix Quality Can Significantly Affect Proximity-Dependent Biotinylation (BioID) Data.	NOA1 OAT MTFP1 BCS1L HARS2 NT5DC2 SUPV3L1	2.50e-03	438	145	7	32628020
Interaction	IL5RA interactions	SEMA6B MAN2B1 NAGLU P4HTM CSF2RB ADAMTS7 GUSB CHPF2 PCSK9	2.52e-07	124	143	9	int:IL5RA
Interaction	C1QB interactions	SEMA6B MAN2B1 NAGLU B3GNT3 ADAMTS7 GUSB CHPF2 PCSK9	3.51e-07	94	143	8	int:C1QB
Interaction	LYZL1 interactions	MAN2B1 HECTD3 ADAM9 NAGLU ADAMTS7 GUSB CHPF2 PCSK9	2.00e-06	118	143	8	int:LYZL1
Interaction	SDF2L1 interactions	SEMA6B ABCA2 MAN2B1 ADAM9 NAGLU RIOX1 B3GNT3 P4HTM ADAMTS7 GUSB CHPF2 PCSK9	3.31e-06	322	143	12	int:SDF2L1
Interaction	FBXO2 interactions	SEMA6B ABCA2 KRT16 MAN2B1 IL25 CADM4 ADAM9 NAGLU B3GNT3 CUL7 MYORG ADAMTS7 GUSB	7.61e-06	411	143	13	int:FBXO2
Interaction	CRISP2 interactions	SEMA6B NAGLU ADAMTS7 CHPF2 PCSK9	9.03e-06	40	143	5	int:CRISP2
Interaction	FIBIN interactions	MAN2B1 ADAM9 ADAMTS7 GUSB CHPF2 PCSK9	1.13e-05	71	143	6	int:FIBIN
Interaction	NCR3 interactions	MAN2B1 ADAM9 NAGLU P4HTM ADAMTS7 GUSB PCSK9	2.38e-05	120	143	7	int:NCR3
Interaction	SFTPC interactions	SEMA6B ABCA2 CADM4 ADAM9 B3GNT3 MYORG LSMEM2 P4HTM CHPF2	3.02e-05	222	143	9	int:SFTPC
Interaction	CBLN4 interactions	SEMA6B ADAM9 NAGLU P4HTM ADAMTS7 GUSB PCSK9	3.44e-05	127	143	7	int:CBLN4
Interaction	TRGV3 interactions	NAGLU ADAMTS7 GUSB CHPF2 PCSK9	4.39e-05	55	143	5	int:TRGV3
Interaction	LY6H interactions	ADAM9 ADAMTS7 GUSB CD36 CHPF2	7.25e-05	61	143	5	int:LY6H
Interaction	NCEH1 interactions	MAN2B1 CADM4 MTFP1 CD1E P4HTM GUSB	9.85e-05	104	143	6	int:NCEH1
GeneFamily	Fibronectin type III domain containing	INSRR MYOM3 DSCAML1 ANOS1 CSF2RB CNTN5 MYOM2	2.63e-05	160	98	7	555
GeneFamily	Phosphatase and actin regulators	PHACTR3 PHACTR1	1.73e-04	4	98	2	679
GeneFamily	Nudix hydrolase family	TRPM2 NUDT11 NUDT10	2.88e-04	24	98	3	667
GeneFamily	Fibronectin type III domain containing\|I-set domain containing\|Myosin binding proteins	MYOM3 MYOM2	7.97e-04	8	98	2	658
GeneFamily	Kelch like\|BTB domain containing	KLHL31 KLHL21 KLHL34	1.52e-03	42	98	3	617
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	BAZ2B BAZ2A	1.55e-03	11	98	2	1025
GeneFamily	ATP binding cassette subfamily A	ABCA2 ABCA6	2.54e-03	14	98	2	805
GeneFamily	StAR related lipid transfer domain containing	STARD13 STARD9	2.92e-03	15	98	2	759
GeneFamily	Immunoglobulin like domain containing	CADM4 MYOM3 DSCAML1 CNTN5 MYOM2	4.01e-03	193	98	5	594
GeneFamily	CD molecules\|Mucins	MUC16 MUC4	5.71e-03	21	98	2	648
Coexpression	GSE3982_MAST_CELL_VS_TH1_UP	AMHR2 IL25 ZNF337 SPATA2 BCS1L HARS2 CD36 YLPM1	1.57e-05	199	145	8	M5453
Coexpression	GSE15930_STIM_VS_STIM_AND_TRICHOSTATINA_72H_CD8_T_CELL_UP	ACLY NLRX1 LGI4 PTPN2 BAZ2A SMARCB1 SLC25A28 SEC23A	1.63e-05	200	145	8	M3648
ToppCell	3'-Distal_airway-Epithelial-Airway_epithelium-respiratory_basal_cell-Basal_resting-Basal_resting_L.0.0.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DENND2A NOA1 CADM4 LMNTD2 ZNF354B ZNF785 AOPEP	1.56e-06	172	145	7	80b565f6e37f38629f4cf89d5b053b3b8517244e
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	KRT16 CADM4 MUC16 OAT ARL4D A4GALT MUC4	3.59e-06	195	145	7	24d226f89dd337c22728688e4b40ca082a0e1fe1
ToppCell	facs-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACLY INSRR CHGB GADD45GIP1 MUC4 PCSK9 PHACTR1	3.59e-06	195	145	7	58b769da05a8f6b05aeb08d4f8b112941087ad00
ToppCell	Parenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_systemic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	SYNM PPFIBP2 LGI4 RPP25 NT5DC2 CNGA1	6.92e-06	141	145	6	dcc56aef1b31bfe0de84cb0b5c77d242681cf19c
ToppCell	droplet-Liver-Hepatocytes-18m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BAZ2B TRPM2 USP25 DPPA3 C2CD3 ZNF558	1.23e-05	156	145	6	d72c2f5f72d269e29033f8728d924e0d4c8772c7
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_mature_unknown_2\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MYOM3 FBXO4 PHACTR3 FAM167A FSCN2 PYGM	1.42e-05	160	145	6	68b477525eeef99430382ff0a6745cac91364bc2
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAG1 TRPM2 RPP25 FBXO4 ZNF436 PHACTR3	1.64e-05	164	145	6	b895674ed2df87db8fbfb30b7e31620945588491
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGI4 ANOS1 STARD9 NT5DC2 PYGM MYOM2	1.69e-05	165	145	6	9de841c1c95967c562720feba930246debc626fd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGI4 ANOS1 STARD9 NT5DC2 PYGM MYOM2	1.69e-05	165	145	6	a612a7d3a5415ecacc3df8fbff0ce498f982aad0
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LGI4 ANOS1 STARD9 NT5DC2 PYGM MYOM2	1.69e-05	165	145	6	cdc94a640ec01c6892521bcd6f0ee0a66ff23866
ToppCell	B_cells-pDCs\|World / Immune cells in Kidney/Urine in Lupus Nephritis	KCTD19 CADM4 RPP25 DNAH12 CSF2RB CD36	1.88e-05	168	145	6	dc8f94424f60ab56facdcffa969e7f3466ee1b6e
ToppCell	3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADAM9 MUC16 B3GNT3 SLC3A1 PHACTR3 MUC4	1.94e-05	169	145	6	40b557549fe08c5dc9dba359af35993d68d1640a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNM ANOS1 NT5DC2 CNTN5 MYOM2 SH3BP5	2.01e-05	170	145	6	99dd734c0972a40d5381e8e2d96bdaa31f6d06e6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal--glomerular_mesenchymal_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNM ANOS1 NT5DC2 CNTN5 MYOM2 SH3BP5	2.01e-05	170	145	6	3a14eeae221b8bb0bd0dadcb8e7a603431240a1e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNM ANOS1 NT5DC2 CNTN5 MYOM2 SH3BP5	2.01e-05	170	145	6	cdb6fad277f284c3fd5a6f45672a8edc24715882
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC75B IL25 CADM4 LGI4 BHMT2 GABRA1	3.33e-05	186	145	6	ea936e66ae4b7b40564711fad60ac0137327995f
ToppCell	Nasal_Brush-Immune-Neutrophils\|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X	TMEM53 ZNF354A HECTD3 P4HTM SLC22A4 DPY19L4	3.33e-05	186	145	6	f5aa91dbef29f7efa2b9a728c6539d7541340cd4
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLK2 PDE9A B3GNT3 ARL4D CD36 GABRA1	3.43e-05	187	145	6	6cf7be5401b81a4eeb30840fb3733d61a24af539
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC75B IL25 CADM4 LGI4 BHMT2 GABRA1	3.43e-05	187	145	6	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC75B IL25 CADM4 LGI4 BHMT2 GABRA1	3.43e-05	187	145	6	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	PND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PLK2 PDE9A B3GNT3 ARL4D CD36 GABRA1	3.43e-05	187	145	6	63834420db930df91b62494c9d7aaa9a25bca530
ToppCell	E12.5-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|E12.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	CADM4 CHGB LGI4 CNTN5 PHACTR3 PHACTR1	3.64e-05	189	145	6	620d30bb6211fff6adab0638d0d994f547167a29
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Inner_Medullary_Collecting_Duct_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PDE9A ZSWIM6 ANOS1 CD36 CNGA1 PHACTR1	3.86e-05	191	145	6	3e828cffa24ded19f591a7ed6c1fe88ad57fdcac
ToppCell	MS-Treg-exh_CD4\|MS / Condition, Cell_class and T cell subcluster	MAN2B1 STAG1 NUFIP1 PHF2 SMG9 PYGM	3.97e-05	192	145	6	c6722bf142c84ccedd99c1a3344085aecb4cbab4
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DENND2A RNF213 DSCAML1 AOPEP PHACTR3 PHACTR1	4.21e-05	194	145	6	e577d9e88390b36b5a09b97fe1026089892275a3
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KRT16 MUC16 OAT ARL4D A4GALT MUC4	4.71e-05	198	145	6	6e047de63ef59dcb47e4fc06b173b2a02fdcf4c9
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-Plasma_B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DPEP1 NUGGC KRT16 KLHL31 FER1L4 A4GALT	4.71e-05	198	145	6	96236fa22545f6f4ff3aa8dc002963db8a3468ce
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DPEP1 MUC16 SLC3A1 PLEKHG4B DNAH12 MUC4	4.71e-05	198	145	6	1fe60443c11d34b6d2671af8f06e0dedc8d1558b
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DPEP1 NUGGC KRT16 KLHL31 FER1L4 A4GALT	4.71e-05	198	145	6	9e0fdd63069d17430cdc25bf4ffc762afd5e1728
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-Plasma_B-Plasma_B\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DPEP1 NUGGC KRT16 KLHL31 FER1L4 A4GALT	4.71e-05	198	145	6	7eb521af938c2609a85d27e2aa7d4317ad6e1e44
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KRT16 OAT ARL4D AOPEP A4GALT MUC4	4.85e-05	199	145	6	974f71b56f66243c78f2f297a1540e0e186df530
ToppCell	Biopsy_Control_(H.)-Epithelial-Basal\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	KRT16 CHGB ANOS1 AOPEP PHACTR3 GABRA1	4.85e-05	199	145	6	6a274a5db02c55bbf31d602b9d5c8394241acdca
ToppCell	Parenchymal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	PLK2 CADM4 MYOM3 CILK1 ZNF106 CSF2RB	4.98e-05	200	145	6	a8b59e6fe04271fef61db911a286b5c48438bb84
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL25 LMNTD2 KLHL31 BHMT2 FSCN2	6.01e-05	127	145	5	25d0b28c9df2d10fbcdb0aca47b75bf5c7c9c430
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL25 LMNTD2 KLHL31 BHMT2 FSCN2	6.01e-05	127	145	5	352d44233a93c926aeb7c5fad49965fd82b873ca
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)--\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL25 LMNTD2 KLHL31 BHMT2 FSCN2	6.01e-05	127	145	5	ca77f85502dd66f3cb4b15cf80f755104ca1e6ff
ToppCell	Hippocampus-Macroglia-CSF_related-CHOROID_PLEXUS-Choroid_Plexus.Ttr_(Ttr)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	IL25 LMNTD2 KLHL31 BHMT2 FSCN2	6.01e-05	127	145	5	b27d5141e661a4c6924aa6d7c5b046f9ae49955d
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Grin2c_(SNc)-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	KCTD19 PLA2G4D F2 KLHL34	6.01e-05	65	145	4	acc541e5a0e4be5ddd5702f191185c5b405b8762
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Th-Inhibitory_Neuron.Th.Grin2c_(SNc)\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	KCTD19 PLA2G4D F2 KLHL34	6.01e-05	65	145	4	b8ab40d75b4078123cdffec2f5326cff65f67578
Disease	phospholipids in very small VLDL measurement	FAM83E ABCA6 TP53BP1 PCSK9	1.11e-04	51	143	4	EFO_0022300
Disease	mastiha supplement exposure measurement, interleukin-6 measurement	TRPM2 SND1	1.39e-04	4	143	2	EFO_0004810, EFO_0600067
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	ZNF106 LLGL1 SLC22A4 TP53BP1 PCSK9	3.16e-04	121	143	5	EFO_0008595, EFO_0020943
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	ZNF106 ABCA6 SLC22A4 TP53BP1 PCSK9	3.94e-04	127	143	5	EFO_0008595, EFO_0020947
Disease	Vasodilators used in cardiac diseases use measurement	RNF213 PCSK9 PHACTR1	5.97e-04	34	143	3	EFO_0009926
Disease	Juvenile Myoclonic Epilepsy	CILK1 GABRA1	6.41e-04	8	143	2	C0270853
Disease	free cholesterol to total lipids in large VLDL percentage	ABCA6 NLRC5 PCSK9	7.67e-04	37	143	3	EFO_0022281
Disease	triglycerides:total lipids ratio, low density lipoprotein cholesterol measurement	ZNF106 ABCA6 SLC22A4 TP53BP1 PCSK9	8.40e-04	150	143	5	EFO_0004611, EFO_0020947
Disease	triglycerides to total lipids in large VLDL percentage	ABCA6 NLRC5 PCSK9	8.96e-04	39	143	3	EFO_0022332
Disease	free cholesterol to total lipids in very small VLDL percentage	ABCA6 TP53BP1 PCSK9	1.19e-03	43	143	3	EFO_0022290
Disease	cholesterol to total lipids in large VLDL percentage	ABCA6 NLRC5 PCSK9	1.36e-03	45	143	3	EFO_0022236
Disease	major depressive episode	BAZ2B FREM3 CNTN5	1.55e-03	47	143	3	EFO_0007634
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	ZNF106 LLGL1 TP53BP1 PCSK9	1.61e-03	103	143	4	EFO_0008595, EFO_0020944
Disease	cholesteryl ester measurement	STAG1 FAM83E ABCA6 NLRC5 TP53BP1 PCSK9	1.63e-03	257	143	6	EFO_0010351
Disease	apolipoprotein B to apolipoprotein A1 ratio	ABCA6 NLRC5 PCSK9	1.74e-03	49	143	3	EFO_0021897
Disease	cholesteryl esters to total lipids in small VLDL percentage	ABCA6 NLRC5 PCSK9	1.74e-03	49	143	3	EFO_0022256
Disease	triglycerides to total lipids in medium LDL percentage	ABCA6 TP53BP1 PCSK9	1.85e-03	50	143	3	EFO_0022334
Disease	cholesterol to total lipids in small VLDL percentage	ABCA6 NLRC5 PCSK9	1.96e-03	51	143	3	EFO_0022242
Disease	sickle cell anemia (is_marker_for)	F2 CD36	2.04e-03	14	143	2	DOID:10923 (is_marker_for)
Disease	Antithrombotic agent use measurement	AOPEP PCSK9 PHACTR1	2.43e-03	55	143	3	EFO_0009925
Disease	free cholesterol to total lipids in medium VLDL percentage	ABCA6 TP53BP1 PCSK9	2.69e-03	57	143	3	EFO_0022284
Disease	phospholipids in small VLDL measurement	ABCA6 TP53BP1 PCSK9	3.12e-03	60	143	3	EFO_0022146
Disease	angina pectoris	RNF213 ADAMTS7 PCSK9 PHACTR1	3.26e-03	125	143	4	EFO_0003913
Disease	migraine disorder, systolic blood pressure	RNF213 PHACTR1	3.39e-03	18	143	2	EFO_0006335, MONDO_0005277
Disease	triglycerides to total lipids in IDL percentage	ABCA6 TP53BP1 PCSK9	3.58e-03	63	143	3	EFO_0022329
Disease	triglycerides to total lipids in medium VLDL percentage	ABCA6 TP53BP1 PCSK9	3.58e-03	63	143	3	EFO_0022335
Disease	cholesterol to total lipids in medium VLDL percentage	ABCA6 TP53BP1 PCSK9	3.58e-03	63	143	3	EFO_0022239
Disease	Disorder of eye	ADAM9 OAT OPA1 FSCN2 CNGA1	3.81e-03	212	143	5	C0015397
Disease	Coronary Arteriosclerosis	ADAMTS7 PCSK9 PHACTR1	3.91e-03	65	143	3	C0010054
Disease	Coronary Artery Disease	ADAMTS7 PCSK9 PHACTR1	3.91e-03	65	143	3	C1956346
Disease	phospholipids:total lipids ratio, intermediate density lipoprotein measurement	ZNF106 LLGL1 TP53BP1	4.26e-03	67	143	3	EFO_0008595, EFO_0020946
Disease	cholesterol to total lipids in very small VLDL percentage	ABCA6 TP53BP1 PCSK9	4.26e-03	67	143	3	EFO_0022245
Disease	stroke, coronary artery disease	ADAMTS7 PHACTR1	4.61e-03	21	143	2	EFO_0000712, EFO_0001645
Disease	triglycerides to total lipids in very small VLDL percentage	ABCA6 TP53BP1 PCSK9	4.62e-03	69	143	3	EFO_0022341
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	ZNF106 ABCA6 NLRC5 TP53BP1 PCSK9	4.62e-03	222	143	5	EFO_0008317, EFO_0020943

Protein segments in the cluster

Peptide	Gene	Start	Entry
EKLRPLWRSYTRRTD	ARL4D	81	P49703
LRELFRDTPLADWYA	A4GALT	146	Q9NPC4
EDSKPYWEARRVARQ	SH3BP5	96	O60239
TEISYEITPRIRVWR	BAZ2A	1631	Q9UIF9
DERELRIPLEYGWQR	BAZ2B	741	Q9UIF8
LEVPARDRSYAWLLS	BCS1L	51	Q9Y276
ETVRDPILWRYFLLR	FBXO4	91	Q9UKT5
DPFSRDQVWSLLRER	ABCA6	646	Q8N139
IREDITYQQPRLTAW	ALKBH3	121	Q96Q83
PERLRWNTNEEIASY	CAMTA2	36	O94983
LVTLPANRWREQLDY	AOPEP	191	Q8N6M6
LCREYPELETRWQDL	DNHD1	3766	Q96M86
VQVYPELESRRERWE	ADAMTS7	206	Q9UKP4
DELWALAVQERRRPY	AMHR2	451	Q16671
YTPRWRLFLEALVDS	NAGLU	671	P54802
PSYRWLRNGTEIDLE	CNTN5	131	O94779
QPEWALDRAYRDARV	P4HTM	486	Q9NXG6
DEVLLVSSSRYPDRW	NUDT10	31	Q8NFP7
WFLTDRRIREDYPQV	RIMKLA	6	Q8IXN7
ELDTQRRWQPLYLEI	PTPN2	11	P17706
GWREYPESVIRLIEE	TIPARP	356	Q7Z3E1
ILEIPALTEAVRWYR	KCTD19	241	Q17RG1
INWPRDATQASYRIR	LLGL1	951	Q15334
ERVQLTDIRPSRWYQ	ANOS1	246	P23352
PRLDREQLYWELSQL	MUC16	13716	Q8WXI7
REERPNYRLECLQWL	MUC4	4551	Q99102
IERYDPGADQWTRLR	KLHL34	541	Q8N239
SLSRDILYRDPENGW	KLHL31	331	Q9H511
LNPLLYTWRNEEFRR	GPR88	331	Q9GZN0
PEEREWRTQQRYLKV	NFRKB	181	Q6P4R8
FVAYQSSPTRRRWRE	IFNLR1	56	Q8IU57
RYFWVPNRILDSEVR	MTMR11	231	A4FU01
WDALSYLNEPVRSRQ	GLB1L3	421	Q8NCI6
LSEILAFPRAWYRRS	KIAA1109	4261	Q2LD37
RFDYLPTEREVSVWR	FER1L4	1556	A9Z1Z3
WNLERITPPRYRADE	PCSK9	156	Q8NBP7
QPLWESRDRYEELKR	PDE9A	541	O76083
PEYQIRWLILRRGDE	CUL7	36	Q14999
AARLAYPESARRDWV	DNAH12	1086	Q6ZR08
DPAARYRNVLEALWR	SLC25A28	106	Q96A46
EVKIRDWYQRQRPSE	KRT16	146	P08779
APYERRVRWLREIQS	LRRC75B	26	Q2VPJ9
PRGAERDLYRDTWVR	MTFP1	6	Q9UDX5
YPTWRRTLLRRAKEE	MICAL1	906	Q8TDZ2
RAEVVYEWTREPARS	GABRA1	191	P14867
RLEDVDWNSVARRYP	LMNTD2	211	Q8IXW0
DEVLLVSSSRYPDRW	NUDT11	31	Q96G61
LAEWFSRLPREERQF	NLRX1	86	Q86UT6
WLRSVDLAEYAPNLR	PPFIBP2	726	Q8ND30
LFSLRVQEPWADRAR	NLRC5	1381	Q86WI3
RKLQERPWLVDSYSE	PANK4	591	Q9NVE7
AQDYDRRADKPWTRL	PHACTR1	531	Q9C0D0
TEWKNNYPRLRELDR	OPA1	576	O60313
QTPVWTEYESILRRA	FUOM	91	A2VDF0
RGDVLPNADETWYLR	CD1E	256	P15812
ALEPSTRYWARVRVR	CSF2RB	401	P32927
EAAYQLALRWVRADP	KLHL21	196	Q9UJP4
PWASLYRERFLSERV	BFAR	196	Q9NZS9
ARARREYWENLLPAS	BHMT2	336	Q9H2M3
TRGPSLLWYFREERL	C2CD3	1476	Q4AC94
RPWDRSLENVYRGSE	DENND2A	241	Q9ULE3
IRWYRNTELVLPDEA	DSCAML1	346	Q8TD84
QVRTLRELLWGYRDP	CD36	171	P16671
VDWKTYTSSDRRLRP	GAS2L2	321	Q8NHY3
YEREVILPERWTQDL	GUSB	101	P08236
RPAATLRWYRDRKEL	CADM4	151	Q8NFZ8
DTTRIEYSIPLRENW	DPY19L4	206	Q7Z388
FTEKTNEIRRAYWRP	ABCA2	631	Q9BZC7
SSYEIITPWRLTRER	ADAM9	41	Q13443
SPSNYVRRELLRRTW	B3GNT3	116	Q9Y2A9
EILERRRDYRPTWKL	MAN2B1	751	O00754
LRPYLTEEARPWDEL	LSMEM2	61	Q8N112
ADRILLRWERYEPLE	INSRR	496	P14616
LRWERYEPLEARDLL	INSRR	501	P14616
QLRELEAEEREWYPS	GADD45GIP1	81	Q8TAE8
AISPWRYELDRDLNR	IL25	86	Q9H293
PDRELQSQWLRAYLE	ETNK1	361	Q9HBU6
YPDLIAELLRRNWTE	DPEP1	321	P16444
PRWLISQRRFREAED	SLC22A4	281	Q9H015
VQAPEDLEWERYRGR	CHGB	351	P05060
YQWIDRIRTPRASNE	C2CD5	176	Q86YS7
LREIEDEWLYSRRGV	DPPA3	71	Q6W0C5
DAPGYRQRLRERLWE	NOA1	256	Q8NC60
WSQRDLEGPIRYARE	PLA2G4D	376	Q86XP0
VPEEDRIWLYLQGRS	NOXRED1	16	Q6NXP6
RLRYRSVREVWQSLP	RPP25	96	Q9BUL9
KLRLETRRPSYLEWQ	FAM167A	36	Q96KS9
TRRPSYLEWQARLEE	FAM167A	41	Q96KS9
SRYLRSDGRLVWEPE	FSCN2	191	O14926
QDYDRRADKPWTRLS	PHACTR3	511	Q96KR7
WRVRIIPDNEYETSE	FREM3	1841	P0C091
PLTWDYVARRELEIE	UTP6	271	Q9NYH9
RRWSRVDDLYTLLPR	STARD13	151	Q9Y3M8
DPYIRTQRRDWDGEA	NUGGC	246	Q68CJ6
VWRRESPTIVQGRYR	HARS2	156	P49590
IRPASANISLYERWR	PHF2	271	O75151
WLNRARLEPLRVYSI	RNF8	86	O76064
RRWATRELYIPSGES	SYNM	1066	O15061
SLRWYQHPTEEELRI	TMEM161B	36	Q8NDZ6
LDLVDAATRRWVPVY	FAM83E	171	Q2M2I3
AATRRWVPVYLLLDR	FAM83E	176	Q2M2I3
LILSWDYSLQRFRPE	LGI4	246	Q8N135
PLEYWNSSVQDDLRR	PTCHD4	526	Q6ZW05
PNERYRLLRRSTEHW	ARHGAP27	31	Q6ZUM4
YIAPWERERRDASEE	SMG9	41	Q9H0W8
TERLGTRERLYEWIS	INPPL1	876	O15357
RRLRIWRDYVAPTAN	SND1	321	Q7KZF4
RYPSLWRRLATVEER	SMARCB1	46	Q12824
RYRIPREILFWLTVA	SLC3A1	81	Q07837
IWDLDLPSRRREYLQ	STARD9	4296	Q9P2P6
QYSRNEPLTFAWLRR	SUPV3L1	596	Q8IYB8
RTGRWLAVDYENVRP	OAT	271	P04181
DRERALSVYGLPIRW	RIOX1	516	Q9H6W3
IYRAETEEGPDVLRW	SEC23A	531	Q15436
YARVTPDTDWARLLQ	ACLY	31	P53396
STRWYRAPEVLLRST	CILK1	161	Q9UPZ9
ELERRYPGTRLAWLA	CHPF2	551	Q9P2E5
WNYPEIRLNRLLRFS	CNGA1	261	P29973
RFRPQWSLRDTLVSY	RNF213	5151	Q63HN8
TELRYQRKLTWRSNP	SEMA6B	96	Q9H3T3
TYRRQDALRPDVWLL	SPATA2	346	Q9UM82
WTLLDPSQRDLYRDV	ZNF778	56	Q96MU6
EEWRPLDAAQRDLYR	ZNF436	26	Q9C0F3
EPTRRYRVWSRILQA	TSNARE1	156	Q96NA8
IARWREERRKNYPTL	NUFIP1	236	Q9UHK0
YAREIWGVEPSRQRL	PYGM	821	P11217
TLEELDPESREYWRR	MRPL54	106	Q6P161
DPESREYWRRLRKQN	MRPL54	111	Q6P161
DLWLQYPQTRLRLEE	PLEKHG4B	586	Q96PX9
ASIRWQVVDRRIPLY	TRPM2	1471	O94759
EWALLDPAQRTLYRD	ZNF558	56	Q96NG5
DRLQDAGSRWPELYL	TMEM53	201	Q6P2H8
RTPTEVWRDSRNPYD	USP25	146	Q9UHP3
VWRDSRNPYDRKRQD	USP25	151	Q9UHP3
ERREDVWLPLISYRN	STAG1	1036	Q8WVM7
GYSLEEQRILDWQPR	TP53BP1	1851	Q12888
DFLRLTEWRGPRVLY	NT5DC2	341	Q9H857
LRIREYPERGDTWRE	YLPM1	1371	P49750
QRRIVYWSFPRSERE	ZSWIM6	106	Q9HCJ5
LDPAQRRLYWDVTLE	ZNF41	86	P51814
PRYNWRENLDRDIAL	F2	451	P00734
SVTDIRRPRLYLLQW	PLK2	591	Q9NYY3
DEWRKLAPSQRNLYR	ZNF354A	26	O60765
DEWRKLAPSQRNLYR	ZNF354B	26	Q96LW1
PQWRREDRIPYQDRE	ZNF106	101	Q9H2Y7
EEWECLRPAQRALYR	ZNF785	41	A8K8V0
WRLLSPAQRALYREV	ZNF337	26	Q9Y3M9
DYRPVLRWEQVVDLT	HECTD3	171	Q5T447
WQYRTGRLADPTRRT	LEG1	96	Q6P5S2
DLKRVQPRAEWYRDD	MYOM2	306	P54296
TWYKNDTRIDPRLFR	MYOM3	186	Q5VTT5
GDVPERELYIRWLEV	MYORG	566	Q6NSJ0