Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	5-diphosphoinositol pentakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	2.49e-06	2	32	2	GO:0033857
GeneOntologyMolecularFunction	inositol hexakisphosphate 3-kinase activity	PPIP5K1 PPIP5K2	1.49e-05	4	32	2	GO:0052724
GeneOntologyMolecularFunction	inositol hexakisphosphate 1-kinase activity	PPIP5K1 PPIP5K2	1.49e-05	4	32	2	GO:0052723
GeneOntologyMolecularFunction	inositol hexakisphosphate 5-kinase activity	PPIP5K1 PPIP5K2	2.48e-05	5	32	2	GO:0000832
GeneOntologyMolecularFunction	diphosphoinositol pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.48e-05	5	32	2	GO:0000829
GeneOntologyMolecularFunction	inositol hexakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.48e-05	5	32	2	GO:0000828
GeneOntologyMolecularFunction	inositol-1,3,4,5,6-pentakisphosphate kinase activity	PPIP5K1 PPIP5K2	2.48e-05	5	32	2	GO:0000827
GeneOntologyMolecularFunction	RNA polymerase II cis-regulatory region sequence-specific DNA binding	SOX1 ETV4 HOXB6 POU5F1B HOXC9 MED12 GLIS1 NFKB2 FOXF2	1.04e-04	1244	32	9	GO:0000978
GeneOntologyMolecularFunction	cis-regulatory region sequence-specific DNA binding	SOX1 ETV4 HOXB6 POU5F1B HOXC9 MED12 GLIS1 NFKB2 FOXF2	1.23e-04	1271	32	9	GO:0000987
GeneOntologyMolecularFunction	inositol phosphate kinase activity	PPIP5K1 PPIP5K2	1.36e-04	11	32	2	GO:0180030
GeneOntologyMolecularFunction	DNA-binding transcription activator activity, RNA polymerase II-specific	SOX1 ETV4 POU5F1B GLIS1 NFKB2 FOXF2	2.31e-04	560	32	6	GO:0001228
GeneOntologyMolecularFunction	DNA-binding transcription activator activity	SOX1 ETV4 POU5F1B GLIS1 NFKB2 FOXF2	2.44e-04	566	32	6	GO:0001216
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	SOX1 ETV4 HOXB6 POU5F1B HOXC9 MED12 GLIS1 NFKB2 FOXF2	3.48e-04	1459	32	9	GO:0000977
GeneOntologyMolecularFunction	semaphorin receptor binding	SEMA4A SEMA7A	6.16e-04	23	32	2	GO:0030215
GeneOntologyMolecularFunction	chemorepellent activity	SEMA4A SEMA7A	9.83e-04	29	32	2	GO:0045499
GeneOntologyMolecularFunction	DNA-binding transcription factor activity, RNA polymerase II-specific	SOX1 ETV4 HOXB6 POU5F1B HOXC9 GLIS1 NFKB2 FOXF2	1.39e-03	1412	32	8	GO:0000981
GeneOntologyMolecularFunction	phosphotransferase activity, phosphate group as acceptor	PPIP5K1 PPIP5K2	1.96e-03	41	32	2	GO:0016776
GeneOntologyMolecularFunction	basal RNA polymerase II transcription machinery binding	ZNF326 FOXF2	5.01e-03	66	32	2	GO:0001099
GeneOntologyMolecularFunction	basal transcription machinery binding	ZNF326 FOXF2	5.01e-03	66	32	2	GO:0001098
GeneOntologyMolecularFunction	ubiquitin-like ligase-substrate adaptor activity	PEF1 PDCD6	7.63e-03	82	32	2	GO:1990756
GeneOntologyMolecularFunction	enzyme-substrate adaptor activity	PEF1 PDCD6	1.01e-02	95	32	2	GO:0140767
GeneOntologyMolecularFunction	calcium-dependent protein binding	PEF1 PDCD6	1.07e-02	98	32	2	GO:0048306
GeneOntologyBiologicalProcess	stem cell differentiation	ETV4 PEF1 POU5F1B SEMA4A PDCD6 SEMA7A	6.65e-06	306	32	6	GO:0048863
GeneOntologyBiologicalProcess	neural crest cell development	PEF1 SEMA4A PDCD6 SEMA7A	1.06e-05	89	32	4	GO:0014032
GeneOntologyBiologicalProcess	stem cell development	PEF1 SEMA4A PDCD6 SEMA7A	1.75e-05	101	32	4	GO:0048864
GeneOntologyBiologicalProcess	neural crest cell differentiation	PEF1 SEMA4A PDCD6 SEMA7A	1.97e-05	104	32	4	GO:0014033
GeneOntologyBiologicalProcess	mesenchyme development	ERBB3 PEF1 SEMA4A PDCD6 SEMA7A FOXF2	2.01e-05	372	32	6	GO:0060485
GeneOntologyBiologicalProcess	positive regulation of protein monoubiquitination	PEF1 PDCD6	2.33e-05	5	32	2	GO:1902527
GeneOntologyBiologicalProcess	regulation of protein monoubiquitination	PEF1 PDCD6	3.48e-05	6	32	2	GO:1902525
GeneOntologyBiologicalProcess	mesenchymal cell differentiation	PEF1 SEMA4A PDCD6 SEMA7A FOXF2	8.62e-05	296	32	5	GO:0048762
GeneOntologyBiologicalProcess	inositol metabolic process	PPIP5K1 PPIP5K2	1.04e-04	10	32	2	GO:0006020
GeneOntologyBiologicalProcess	anatomical structure formation involved in morphogenesis	GLUL PEF1 POFUT1 POU5F1B SEMA4A PDCD6 MED12 CYP19A1 NFKB2	3.09e-04	1483	32	9	GO:0048646
GeneOntologyBiologicalProcess	neural crest formation	PEF1 PDCD6	3.13e-04	17	32	2	GO:0014029
GeneOntologyBiologicalProcess	chordate embryonic development	HOXB6 PEF1 POFUT1 POU5F1B HOXC9 PDCD6 MED12	3.96e-04	906	32	7	GO:0043009
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	HOXB6 PEF1 POFUT1 POU5F1B HOXC9 PDCD6 MED12	4.60e-04	929	32	7	GO:0009792
GeneOntologyBiologicalProcess	hormone catabolic process	DIO3 CYP19A1	4.81e-04	21	32	2	GO:0042447
GeneOntologyBiologicalProcess	anterior/posterior pattern specification	HOXB6 POFUT1 HOXC9 MED12	5.54e-04	247	32	4	GO:0009952
GeneOntologyBiologicalProcess	embryonic skeletal system morphogenesis	HOXB6 HOXC9 MED12	6.37e-04	109	32	3	GO:0048704
GeneOntologyBiologicalProcess	regionalization	SOX1 HOXB6 POFUT1 HOXC9 MED12	7.86e-04	478	32	5	GO:0003002
GeneOntologyBiologicalProcess	vesicle targeting, rough ER to cis-Golgi	PEF1 PDCD6	7.99e-04	27	32	2	GO:0048207
GeneOntologyBiologicalProcess	COPII vesicle coating	PEF1 PDCD6	7.99e-04	27	32	2	GO:0048208
GeneOntologyBiologicalProcess	spinal cord development	SOX1 SCYL1 MED12	8.22e-04	119	32	3	GO:0021510
GeneOntologyBiologicalProcess	inositol phosphate biosynthetic process	PPIP5K1 PPIP5K2	1.05e-03	31	32	2	GO:0032958
GeneOntologyCellularComponent	vesicle coat	SCYL1 PEF1 PDCD6	1.46e-04	67	32	3	GO:0030120
GeneOntologyCellularComponent	COPII vesicle coat	PEF1 PDCD6	2.69e-04	16	32	2	GO:0030127
GeneOntologyCellularComponent	membrane coat	SCYL1 PEF1 PDCD6	5.65e-04	106	32	3	GO:0030117
GeneOntologyCellularComponent	coated membrane	SCYL1 PEF1 PDCD6	5.65e-04	106	32	3	GO:0048475
GeneOntologyCellularComponent	chromatin	SOX1 ETV4 HOXB6 POU5F1B HOXC9 AKAP8 NFKB2 FOXF2	1.40e-03	1480	32	8	GO:0000785
GeneOntologyCellularComponent	Cul3-RING ubiquitin ligase complex	PEF1 PDCD6	1.62e-03	39	32	2	GO:0031463
GeneOntologyCellularComponent	coated vesicle membrane	SCYL1 PEF1 PDCD6	4.27e-03	215	32	3	GO:0030662
GeneOntologyCellularComponent	ER to Golgi transport vesicle membrane	PEF1 PDCD6	4.31e-03	64	32	2	GO:0012507
Domain	ZF_C2H2_AKAP95	ZNF326 AKAP8	7.48e-06	3	30	2	PS51799
Domain	AKAP95	ZNF326 AKAP8	7.48e-06	3	30	2	IPR007071
Domain	AKAP95	ZNF326 AKAP8	7.48e-06	3	30	2	PF04988
Domain	Plexin_repeat	SEMA4A SEMA7A ATRNL1	1.80e-05	32	30	3	IPR002165
Domain	PSI	SEMA4A SEMA7A ATRNL1	1.80e-05	32	30	3	PF01437
Domain	Acid_Pase_AS	PPIP5K1 PPIP5K2	3.73e-05	6	30	2	IPR033379
Domain	PSI	SEMA4A SEMA7A ATRNL1	4.74e-05	44	30	3	IPR016201
Domain	HIS_ACID_PHOSPHAT_2	PPIP5K1 PPIP5K2	5.21e-05	7	30	2	PS00778
Domain	HIS_ACID_PHOSPHAT_1	PPIP5K1 PPIP5K2	5.21e-05	7	30	2	PS00616
Domain	PSI	SEMA4A SEMA7A ATRNL1	5.42e-05	46	30	3	SM00423
Domain	His_Pase_clade-2	PPIP5K1 PPIP5K2	6.94e-05	8	30	2	IPR000560
Domain	His_Phos_2	PPIP5K1 PPIP5K2	6.94e-05	8	30	2	PF00328
Domain	Semaphorin	SEMA4A SEMA7A	4.65e-04	20	30	2	IPR027231
Domain	His_PPase_superfam	PPIP5K1 PPIP5K2	4.65e-04	20	30	2	IPR029033
Domain	-	PPIP5K1 PPIP5K2	4.65e-04	20	30	2	3.40.50.1240
Domain	SEMA	SEMA4A SEMA7A	1.13e-03	31	30	2	PS51004
Domain	Sema	SEMA4A SEMA7A	1.13e-03	31	30	2	SM00630
Domain	Semap_dom	SEMA4A SEMA7A	1.13e-03	31	30	2	IPR001627
Domain	Sema	SEMA4A SEMA7A	1.13e-03	31	30	2	PF01403
Domain	Homeobox_CS	HOXB6 POU5F1B HOXC9	3.24e-03	186	30	3	IPR017970
Domain	Homeobox	HOXB6 POU5F1B HOXC9	6.14e-03	234	30	3	PF00046
Domain	HOMEOBOX_1	HOXB6 POU5F1B HOXC9	6.29e-03	236	30	3	PS00027
Domain	HOX	HOXB6 POU5F1B HOXC9	6.36e-03	237	30	3	SM00389
Domain	Homeobox_dom	HOXB6 POU5F1B HOXC9	6.51e-03	239	30	3	IPR001356
Domain	HOMEOBOX_2	HOXB6 POU5F1B HOXC9	6.51e-03	239	30	3	PS50071
Domain	EF-hand_7	PEF1 PDCD6	8.20e-03	85	30	2	PF13499
Domain	Homeobox_metazoa	HOXB6 HOXC9	9.15e-03	90	30	2	IPR020479
Domain	-	HOXB6 POU5F1B HOXC9	1.03e-02	283	30	3	1.10.10.60
Domain	Homeodomain-like	HOXB6 POU5F1B HOXC9	1.58e-02	332	30	3	IPR009057
Pathway	REACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL	PPIP5K1 PPIP5K2	9.44e-05	10	21	2	M27051
Pathway	REACTOME_SYNTHESIS_OF_PYROPHOSPHATES_IN_THE_CYTOSOL	PPIP5K1 PPIP5K2	9.44e-05	10	21	2	MM14709
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	SEMA4A SEMA7A	1.90e-04	14	21	2	MM15047
Pathway	WP_CLASSICAL_PATHWAY_OF_STEROIDOGENESIS_WITH_GLUCOCORTICOID_AND_MINERALOCORTICOID_METABOLISM	HSD11B2 CYP19A1	2.50e-04	16	21	2	M39815
Pathway	REACTOME_OTHER_SEMAPHORIN_INTERACTIONS	SEMA4A SEMA7A	3.56e-04	19	21	2	M10959
Pubmed	Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons.	ETV4 HOXB6 HOXC9	5.72e-07	18	32	3	23359544
Pubmed	Structural analysis and detection of biological inositol pyrophosphates reveal that the family of VIP/diphosphoinositol pentakisphosphate kinases are 1/3-kinases.	PPIP5K1 PPIP5K2	8.20e-07	2	32	2	18981179
Pubmed	Purification, sequencing, and molecular identification of a mammalian PP-InsP5 kinase that is activated when cells are exposed to hyperosmotic stress.	PPIP5K1 PPIP5K2	8.20e-07	2	32	2	17702752
Pubmed	ALG-2 and peflin regulate COPII targeting and secretion in response to calcium signaling.	PEF1 PDCD6	8.20e-07	2	32	2	34762908
Pubmed	Th1 cells promote neurite outgrowth from cortical neurons via a mechanism dependent on semaphorins.	SEMA4A SEMA7A	8.20e-07	2	32	2	20946887
Pubmed	The Significance of the Bifunctional Kinase/Phosphatase Activities of Diphosphoinositol Pentakisphosphate Kinases (PPIP5Ks) for Coupling Inositol Pyrophosphate Cell Signaling to Cellular Phosphate Homeostasis.	PPIP5K1 PPIP5K2	8.20e-07	2	32	2	28126903
Pubmed	Both ALG-2 and peflin, penta-EF-hand (PEF) proteins, are stabilized by dimerization through their fifth EF-hand regions.	PEF1 PDCD6	8.20e-07	2	32	2	11883899
Pubmed	Cloning and characterization of two human VIP1-like inositol hexakisphosphate and diphosphoinositol pentakisphosphate kinases.	PPIP5K1 PPIP5K2	8.20e-07	2	32	2	17690096
Pubmed	Peflin and ALG-2, members of the penta-EF-hand protein family, form a heterodimer that dissociates in a Ca2+-dependent manner.	PEF1 PDCD6	8.20e-07	2	32	2	11278427
Pubmed	A census of human transcription factors: function, expression and evolution.	SOX1 ETV4 HOXB6 POU5F1B HOXC9 GLIS1 NFKB2 FOXF2	1.26e-06	908	32	8	19274049
Pubmed	PPIP5K2 and PCSK1 are Candidate Genetic Contributors to Familial Keratoconus.	PPIP5K1 PPIP5K2	2.46e-06	3	32	2	31852976
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	GLUL TNS2 PPIP5K1 HOXB6 ZNF326 HOXC9 HSD11B2 AKAP8	3.02e-06	1021	32	8	26760575
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	SOX1 ETV4 HOXB6 ZNF326 POU5F1B GLIS1 NFKB2	7.22e-06	808	32	7	20412781
Pubmed	Oct4 is required ~E7.5 for proliferation in the primitive streak.	SOX1 POU5F1B	8.19e-06	5	32	2	24244203
Pubmed	The PEF family proteins sorcin and grancalcin interact in vivo and in vitro.	PEF1 PDCD6	8.19e-06	5	32	2	12804766
Pubmed	Quiescent Oct4+ Neural Stem Cells (NSCs) Repopulate Ablated Glial Fibrillary Acidic Protein+ NSCs in the Adult Mouse Brain.	SOX1 POU5F1B	8.19e-06	5	32	2	28733998
Pubmed	The penta-EF-hand domain of ALG-2 interacts with amino-terminal domains of both annexin VII and annexin XI in a Ca2+-dependent manner.	PEF1 PDCD6	8.19e-06	5	32	2	12445460
Pubmed	Generation of conditional Hoxc8 loss-of-function and Hoxc8-->Hoxc9 replacement alleles in mice.	ETV4 HOXC9	1.23e-05	6	32	2	19621436
Pubmed	Genetic interaction of Pax3 mutation and canonical Wnt signaling modulates neural tube defects and neural crest abnormalities.	SOX1 ERBB3	1.23e-05	6	32	2	34490995
Pubmed	The expression profile of the tumor suppressor gene Lzts1 suggests a role in neuronal development.	SOX1 POU5F1B	2.29e-05	8	32	2	22419569
Pubmed	Expression patterns of long noncoding RNAs from Dlk1-Dio3 imprinted region and the potential mechanisms of Gtl2 activation during blastocyst development.	DIO3 POU5F1B	3.67e-05	10	32	2	26005002
Pubmed	A role for neuregulin1 signaling in muscle spindle differentiation.	ETV4 ERBB3	3.67e-05	10	32	2	12495620
Pubmed	Noggin and chordin have distinct activities in promoting lineage commitment of mouse embryonic stem (ES) cells.	SOX1 POU5F1B	4.49e-05	11	32	2	11969257
Pubmed	Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape.	HOXB6 HOXC9	5.38e-05	12	32	2	27856734
Pubmed	The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.	HOXB6 HOXC9	6.36e-05	13	32	2	8887324
Pubmed	Activin/nodal signaling and NANOG orchestrate human embryonic stem cell fate decisions by controlling the H3K4me3 chromatin mark.	SOX1 POU5F1B	6.36e-05	13	32	2	25805847
Pubmed	Organization and expression of mouse Hox3 cluster genes.	HOXB6 HOXC9	7.41e-05	14	32	2	8099712
Pubmed	Dlk1-Dio3 locus-derived lncRNAs perpetuate postmitotic motor neuron cell fate and subtype identity.	ETV4 DIO3	7.41e-05	14	32	2	30311912
Pubmed	The function of growth/differentiation factor 11 (Gdf11) in rostrocaudal patterning of the developing spinal cord.	ETV4 HOXC9	7.41e-05	14	32	2	16790475
Pubmed	Blocking PPARγ interaction facilitates Nur77 interdiction of fatty acid uptake and suppresses breast cancer progression.	ZNF326 MCCC2 AKAP8	7.87e-05	90	32	3	33087562
Pubmed	Tcf7l1 prepares epiblast cells in the gastrulating mouse embryo for lineage specification.	SOX1 POU5F1B	8.55e-05	15	32	2	23487311
Pubmed	Stem cell factor Sox2 and its close relative Sox3 have differentiation functions in oligodendrocytes.	GLUL SOX1	9.76e-05	16	32	2	24257626
Pubmed	Hox patterning of the vertebrate rib cage.	HOXB6 HOXC9	1.11e-04	17	32	2	17626057
Pubmed	Oct4 regulates the embryonic axis and coordinates exit from pluripotency and germ layer specification in the mouse embryo.	SOX1 POU5F1B	1.11e-04	17	32	2	29915126
Pubmed	Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment.	SOX1 POU5F1B	1.11e-04	17	32	2	20573702
Pubmed	Changes in thyroid status during perinatal development of MCT8-deficient male mice.	DIO3 SEMA7A	1.24e-04	18	32	2	23696569
Pubmed	Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice.	HOXB6 HOXC9	1.24e-04	18	32	2	9639506
Pubmed	Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Müller Glia Dedifferentiation in a Murine Model of Retinal Injury.	GLUL POU5F1B	1.24e-04	18	32	2	27895551
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ETV4 HOXB6 HOXC9 GLIS1 NFKB2	1.31e-04	544	32	5	28473536
Pubmed	Neurites from trigeminal ganglion explants grown in vitro are repelled or attracted by tooth-related tissues depending on developmental stage.	SEMA4A SEMA7A	1.39e-04	19	32	2	15051154
Pubmed	Post-gastrulation synthetic embryos generated ex utero from mouse naive ESCs.	SOX1 POU5F1B	1.39e-04	19	32	2	35988542
Pubmed	Oct4 Is a Key Regulator of Vertebrate Trunk Length Diversity.	HOXB6 POU5F1B	1.39e-04	19	32	2	27453501
Pubmed	HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo.	SOX1 POU5F1B	1.54e-04	20	32	2	10498685
Pubmed	Proteomic dissection of cell type-specific H2AX-interacting protein complex associated with hepatocellular carcinoma.	PEF1 POFUT1 PDCD6	1.63e-04	115	32	3	20000738
Pubmed	NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis.	ERBB3 POU5F1B	1.70e-04	21	32	2	30040984
Pubmed	Motor neurons use push-pull signals to direct vascular remodeling critical for their connectivity.	SEMA4A SEMA7A	1.70e-04	21	32	2	36240771
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	PEF1 C5orf24 AKAP8 PDCD6 NFKB2 FOXF2	1.72e-04	922	32	6	27609421
Pubmed	Organization of human class I homeobox genes.	HOXB6 HOXC9	1.87e-04	22	32	2	2576652
Pubmed	Ets2 is necessary in trophoblast for normal embryonic anteroposterior axis development.	SOX1 POU5F1B	1.87e-04	22	32	2	16481355
Pubmed	Co-adaptor driven assembly of a CUL3 E3 ligase complex.	PEF1 PDCD6	1.87e-04	22	32	2	35120648
Pubmed	The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities.	SOX1 POU5F1B	1.87e-04	22	32	2	21896659
Pubmed	Genome-wide microarray comparison reveals downstream genes of Pax6 in the developing mouse cerebellum.	HSD11B2 SEMA7A	2.05e-04	23	32	2	22817342
Pubmed	Divergent Hox Coding and Evasion of Retinoid Signaling Specifies Motor Neurons Innervating Digit Muscles.	ETV4 HOXC9	2.05e-04	23	32	2	28190640
Pubmed	BMP signalling inhibits premature neural differentiation in the mouse embryo.	SOX1 POU5F1B	2.24e-04	24	32	2	17699604
Pubmed	The absence of Prep1 causes p53-dependent apoptosis of mouse pluripotent epiblast cells.	SOX1 POU5F1B	2.24e-04	24	32	2	20826531
Pubmed	Dimerization quality control ensures neuronal development and survival.	PEF1 PDCD6	2.24e-04	24	32	2	30190310
Pubmed	Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.	HOXB6 HOXC9	2.24e-04	24	32	2	9367423
Pubmed	A semaphorin code defines subpopulations of spinal motor neurons during mouse development.	ETV4 SEMA7A	2.24e-04	24	32	2	15869472
Pubmed	Spry1 and Spry2 are necessary for lens vesicle separation and corneal differentiation.	SOX1 ETV4	2.43e-04	25	32	2	21743007
Pubmed	Transcriptional regulatory networks in epiblast cells and during anterior neural plate development as modeled in epiblast stem cells.	SOX1 POU5F1B	2.63e-04	26	32	2	22992956
Pubmed	Fine mapping of human HOX gene clusters.	HOXB6 HOXC9	2.63e-04	26	32	2	8646877
Pubmed	Multipotent peripheral glial cells generate neuroendocrine cells of the adrenal medulla.	SOX1 ERBB3	2.63e-04	26	32	2	28684471
Pubmed	Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast.	SOX1 POU5F1B	3.05e-04	28	32	2	11412024
Pubmed	Mediator and cohesin connect gene expression and chromatin architecture.	POU5F1B MED12	3.05e-04	28	32	2	20720539
Pubmed	Noggin is required for correct guidance of dorsal root ganglion axons.	SEMA4A SEMA7A	3.28e-04	29	32	2	12435358
Pubmed	The human HOX gene family.	HOXB6 HOXC9	3.28e-04	29	32	2	2574852
Pubmed	GDE2 regulates subtype-specific motor neuron generation through inhibition of Notch signaling.	ETV4 HOXC9	3.51e-04	30	32	2	21943603
Pubmed	Critical role of the p400/mDomino chromatin-remodeling ATPase in embryonic hematopoiesis.	HOXB6 HOXC9	4.00e-04	32	32	2	17535249
Pubmed	Dgcr8 functions in the secondary heart field for outflow tract and right ventricle development in mammals.	ERBB3 FOXF2	4.00e-04	32	32	2	38110169
Pubmed	Sf3b4 regulates chromatin remodeler splicing and Hox expression.	HOXB6 HOXC9	4.00e-04	32	32	2	37167859
Pubmed	Hox repertoires for motor neuron diversity and connectivity gated by a single accessory factor, FoxP1.	ETV4 HOXC9	4.25e-04	33	32	2	18662545
Pubmed	Selective neuronal lineages derived from Dll4-expressing progenitors/precursors in the retina and spinal cord.	GLUL SOX1	4.25e-04	33	32	2	25179941
Pubmed	Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.	SOX1 POU5F1B	4.52e-04	34	32	2	18539113
Pubmed	Lrp4 and Wise interplay controls the formation and patterning of mammary and other skin appendage placodes by modulating Wnt signaling.	ETV4 ERBB3	4.52e-04	34	32	2	23293290
Pubmed	MEGF10 and MEGF11 mediate homotypic interactions required for mosaic spacing of retinal neurons.	GLUL SEMA7A	4.79e-04	35	32	2	22407321
Pubmed	An Oct4-centered protein interaction network in embryonic stem cells.	POU5F1B AKAP8 MED12	4.87e-04	167	32	3	20362541
Pubmed	Global control of motor neuron topography mediated by the repressive actions of a single hox gene.	ETV4 HOXC9	5.07e-04	36	32	2	20826310
Pubmed	Genetic variation in the estrogen metabolic pathway and mammographic density as an intermediate phenotype of breast cancer.	HSD11B2 CYP19A1	5.65e-04	38	32	2	20214802
Pubmed	Atlas of Hox gene expression in the developing kidney.	HOXB6 HOXC9	5.65e-04	38	32	2	15042701
Pubmed	Complete mutation analysis panel of the 39 human HOX genes.	HOXB6 HOXC9	5.65e-04	38	32	2	11857506
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	POU5F1B MCCC2 MED12 USP24	5.67e-04	418	32	4	34709266
Pubmed	Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.	HOXB6 HOXC9	5.95e-04	39	32	2	33257809
Pubmed	Quantification of Hox and surfactant protein-B transcription during murine lung development.	HOXB6 HOXC9	6.26e-04	40	32	2	19204410
Pubmed	NOTCH activation interferes with cell fate specification in the gastrulating mouse embryo.	SOX1 POU5F1B	6.26e-04	40	32	2	26534985
Pubmed	Cdx and T Brachyury Co-activate Growth Signaling in the Embryonic Axial Progenitor Niche.	ETV4 HOXC9	6.26e-04	40	32	2	28009287
Pubmed	Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.	POFUT1 MED12	6.58e-04	41	32	2	8724849
Pubmed	Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates.	HOXB6 HOXC9	6.58e-04	41	32	2	32479258
Pubmed	Reduction of Hox gene expression by histone H1 depletion.	HOXB6 HOXC9	7.23e-04	43	32	2	22701719
Pubmed	Nomenclature for human homeobox genes.	HOXB6 HOXC9	7.57e-04	44	32	2	1973146
Pubmed	Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice.	ETV4 PPIP5K1	7.92e-04	45	32	2	28973166
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	PEF1 ZNF326 AKAP8 MED12	8.23e-04	462	32	4	31138677
Pubmed	NANOG initiates epiblast fate through the coordination of pluripotency genes expression.	ETV4 POU5F1B	8.28e-04	46	32	2	35729116
Pubmed	Vertebrate homeobox gene nomenclature.	HOXB6 HOXC9	8.64e-04	47	32	2	1358459
Pubmed	The emergent landscape of the mouse gut endoderm at single-cell resolution.	HOXB6 HOXC9	9.01e-04	48	32	2	30959515
Interaction	KLHL12 interactions	SCYL1 PEF1 PDCD6 MED12	1.89e-05	104	31	4	int:KLHL12
Cytoband	1p32.3	GLIS1 USP24	8.40e-04	61	32	2	1p32.3
Cytoband	Ensembl 112 genes in cytogenetic band chr12q13	TNS2 ERBB3 HOXC9	3.16e-03	423	32	3	chr12q13
GeneFamily	Immunoglobulin like domain containing\|Semaphorins	SEMA4A SEMA7A	3.43e-04	20	25	2	736
GeneFamily	HOXL subclass homeoboxes	HOXB6 HOXC9	2.33e-03	52	25	2	518
Coexpression	GSE37301_HEMATOPOIETIC_STEM_CELL_VS_RAG2_KO_NK_CELL_UP	POFUT1 AKAP8 ATRNL1 USP24	5.83e-05	174	32	4	M8885
Coexpression	GSE27786_LSK_VS_NKTCELL_DN	ETV4 HSD11B2 MED12 USP24	9.62e-05	198	32	4	M4756
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	SOX1 ERBB3 SEMA7A FOXF2	1.21e-04	210	32	4	M2010
Coexpression	MEISSNER_NPC_HCP_WITH_H3K27ME3	DIO3 HOXB6 AJM1	1.23e-04	79	32	3	M1932
Coexpression	MEISSNER_NPC_HCP_WITH_H3K27ME3	DIO3 HOXB6 AJM1	1.27e-04	80	32	3	MM817
Coexpression	MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3	SOX1 ERBB3 SEMA7A FOXF2	1.37e-04	217	32	4	MM861
Coexpression	SMID_BREAST_CANCER_RELAPSE_IN_BRAIN_DN	ERBB3 MCCC2 CRIP1	1.37e-04	82	32	3	M244
Coexpression	SWEET_LUNG_CANCER_KRAS_DN	GLUL TNS2 SEMA7A CRIP1 FOXF2	1.49e-04	422	32	5	M7396
Coexpression	SMID_BREAST_CANCER_BASAL_DN	PPIP5K1 HOXB6 ERBB3 MCCC2 ATRNL1 CRIP1	1.76e-04	699	32	6	M4960
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	DIO3 HOXC9 HSD11B2 SEMA7A AJM1	1.77e-04	438	32	5	M1954
Coexpression	MIKKELSEN_MCV6_HCP_WITH_H3K27ME3	DIO3 HOXC9 HSD11B2 SEMA7A AJM1	1.81e-04	440	32	5	MM832
Coexpression	SWEET_LUNG_CANCER_KRAS_DN	GLUL TNS2 SEMA7A CRIP1 FOXF2	1.88e-04	444	32	5	MM1051
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GLUL ETV4 ERBB3 CRIP1	1.19e-05	198	32	4	2ada078be27588ab46f2d4e53d20f8e9bc8761df
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Fibroblasts-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	DIO3 GLIS1 ATRNL1 FOXF2	1.24e-05	200	32	4	16a3685c41194a0a4a772e4eee372160263480e0
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNS2 ERBB3 ATRNL1	1.85e-04	155	32	3	77fdae85d36efb776db977eb424b32487ef222e4
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TNS2 CRIP1 FOXF2	1.85e-04	155	32	3	d8b5145258f075b15080f8739f537f48dd22225e
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell-Peri-Peri_Kcnj8\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TNS2 CRIP1 FOXF2	1.85e-04	155	32	3	ced64e26962c5c6e6d539f361fe57ab0b399e999
ToppCell	primary_visual_cortex-Non-neuronal-pericyte_cell\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	TNS2 CRIP1 FOXF2	1.85e-04	155	32	3	0f24ef6486aef354f0911c06932cb01d1a0525ac
ToppCell	TCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Papillary_Muscle_Invasive_Urothelial_Carcinoma\|TCGA-Bladder / Sample_Type by Project: Shred V9	PPIP5K1 HOXB6 ERBB3	1.96e-04	158	32	3	dc559503bab3ec1b9ea54ef2e896d1be33e5344c
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D2\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	SCYL1 TNS2 ERBB3	2.07e-04	161	32	3	58381131e651744b5141b202f9d6063f55432db5
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNS2 HSD11B2 FOXF2	2.10e-04	162	32	3	c5eee02836efde2108534679850c28d2b2cfce3f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GLUL SEMA7A NFKB2	2.43e-04	170	32	3	be2a34c70665d8d11332b1a70eda03d77cb7f7dd
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV4 POU5F1B ZAN	2.64e-04	175	32	3	2fbffcb843f364645b99d1211698d96092abc5ef
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-stromal_related-Germ\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV4 POU5F1B ZAN	2.64e-04	175	32	3	d0d5ae2a9357aa183ab720c891d86b80c9822930
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DIO3 HOXB6 FOXF2	2.78e-04	178	32	3	8ec2a25dda96c9cc9c2904b6cb18f75a293f4969
ToppCell	cellseq2-Mesenchymal-Fibroblastic-Fibroblastic_2\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DIO3 HOXB6 FOXF2	2.78e-04	178	32	3	6c91331196696e0cf239d105f458e3230659fa38
ToppCell	P03-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ETV4 HOXB6 FOXF2	2.78e-04	178	32	3	7975bf0a3146ee0efa4f547af5977e6bf0ba71fd
ToppCell	nucseq-Epithelial-Epithelial_Glandular\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ERBB3 HOXC9 CYP19A1	2.82e-04	179	32	3	859cd8ee414ad6207c046ada2e655e49322dd01c
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ETV4 DIO3 POFUT1	2.87e-04	180	32	3	c3d1521ac90f2e3fc31158e6e61907e05c37af39
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ERBB3 HOXC9 CYP19A1	2.87e-04	180	32	3	3dc80bc636bf0e6ffc9762853132a9fe59fd1f66
ToppCell	nucseq-Epithelial-Epithelial_Glandular-Goblet-Goblet\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ERBB3 HOXC9 CYP19A1	2.87e-04	180	32	3	668a2d8e1d5a390309d5eb62c836f5903144bea9
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-NK_bright-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HOXC9 SEMA7A CRIP1	2.91e-04	181	32	3	4795833e0ec49287bd7809ecfe523fc527565fba
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DIO3 HOXB6 FOXF2	2.91e-04	181	32	3	eea943fdcbef0bbaa8578f3296923e874893b405
ToppCell	systemic_lupus_erythematosus-treated-Lymphocytic_NK-NK_bright\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HOXC9 SEMA7A CRIP1	2.91e-04	181	32	3	208cdccc2f0d0f2d8ec321064c63aed206d46c32
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DIO3 HOXB6 FOXF2	2.91e-04	181	32	3	9c157de9d3403e092c907599f2a2c16db5b21131
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DIO3 HOXB6 FOXF2	3.01e-04	183	32	3	bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCell	5'-GW_trimst-1-SmallIntestine-Neuronal-neuron_precursor-Neuroblast\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV4 ERBB3 CYP19A1	3.06e-04	184	32	3	7aa245b73e10fd73d292e822de6b72920aa12355
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Pericyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TNS2 CRIP1 FOXF2	3.11e-04	185	32	3	0e26a71fea526ebfe3b2d1c8d0d6d9b70282bbe9
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Mesenchymal-Mes-Pericyte-Peri_L1-6_MUSTN1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TNS2 CRIP1 FOXF2	3.11e-04	185	32	3	b3320b794b22e654a33f28b575c9f00023baf5f0
ToppCell	Thalamus-Endothelial\|Thalamus / BrainAtlas - Mouse McCarroll V32	TNS2 CRIP1 FOXF2	3.16e-04	186	32	3	dcc6e4417c4123d5ca6b96fa8ca4874626aaebdb
ToppCell	Frontal_cortex-Endothelial\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	TNS2 CRIP1 FOXF2	3.26e-04	188	32	3	a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCell	droplet-Kidney-nan-21m-Epithelial-kidney_collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ETV4 HOXB6 HSD11B2	3.26e-04	188	32	3	315ce1736e3a84a63a8d5dfa70d411b501cb2532
ToppCell	Entopeduncular-Endothelial\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	TNS2 CRIP1 FOXF2	3.26e-04	188	32	3	94774652fd42bad5012356672ffac8b6d2c22d37
ToppCell	Substantia_nigra-Endothelial\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	TNS2 CRIP1 FOXF2	3.31e-04	189	32	3	bef8234bd9c4d6e3cdef0791d8066b39ba56ebba
ToppCell	Globus_pallidus-Endothelial\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	TNS2 CRIP1 FOXF2	3.31e-04	189	32	3	ad7dc9d25edd68fb624380a082c389fe7d640e7d
ToppCell	Striatum-Endothelial\|Striatum / BrainAtlas - Mouse McCarroll V32	TNS2 CRIP1 FOXF2	3.31e-04	189	32	3	95ee3b6d7fbbfcf91c780dfcd0926acec05f0a2d
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SOX1 ERBB3 ATRNL1	3.36e-04	190	32	3	6c7e1086c0a274cd5527c3104106e372811c9905
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GLUL ETV4 CRIP1	3.36e-04	190	32	3	5eaf03a98ab24d7cfd471cb035aa1d2ec6e6e28c
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ETV4 HOXB6 ATRNL1	3.36e-04	190	32	3	71a00f63fdd4eb4cc6f190d37e7a0417cdaafacb
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ETV4 ATRNL1 FOXF2	3.46e-04	192	32	3	c4efc170852abbcf0c53c2b0f8a0cc9fe7f116c8
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ETV4 ATRNL1 FOXF2	3.46e-04	192	32	3	4c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCell	ILEUM-inflamed-(3)_MNP-(3)_mature_DC\|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	SEMA7A CRIP1 NFKB2	3.52e-04	193	32	3	d9be4d1de863fffc2240d6fd1a2f8dfb2d2bc916
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TNS2 HOXC9 HSD11B2	3.52e-04	193	32	3	cf2461af78f65616ce40d552ee9452295e3895ed
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	ETV4 ATRNL1 FOXF2	3.52e-04	193	32	3	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo-stroma-adipo-CAR\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TNS2 HOXC9 HSD11B2	3.52e-04	193	32	3	e4ea7ce011a80b81b841c907719aa532bed39d2e
ToppCell	10x5'v1-week_12-13-Mesenchymal_adipo\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	TNS2 HOXC9 HSD11B2	3.52e-04	193	32	3	6ef9007c9d18fb775d08fb20cdf954a28d54d7eb
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ETV4 ATRNL1 FOXF2	3.57e-04	194	32	3	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	LAM-LAM\|LAM / Condition, Lineage and Cell class	HOXC9 GLIS1 ATRNL1	3.57e-04	194	32	3	4c6561a64711c72c4ef4a3e67c41d2e8d31fba57
ToppCell	LAM-LAM-LAM+\|LAM / Condition, Lineage and Cell class	HOXC9 GLIS1 ATRNL1	3.57e-04	194	32	3	4ba73a9145ed44896e359f6df9c1f32bbe24a189
ToppCell	Mild/Remission-B_memory-0\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SEMA7A CRIP1 NFKB2	3.57e-04	194	32	3	4866093b50cdf895f06b60684cc3aaa9769aa4dc
ToppCell	Cerebellum-Endothelial\|Cerebellum / BrainAtlas - Mouse McCarroll V32	TNS2 CRIP1 FOXF2	3.62e-04	195	32	3	2192fd9b4682054776f0716933aed5a4a9412657
ToppCell	PCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ERBB3 HSD11B2 CRIP1	3.62e-04	195	32	3	98dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCell	Posterior_cortex-Endothelial\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TNS2 CRIP1 FOXF2	3.62e-04	195	32	3	988e3449691cc228cb55e5e30355136c97b12262
ToppCell	normal_Lymph_Node-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	SEMA4A CRIP1 NFKB2	3.62e-04	195	32	3	5de6841fa04f6fe6f0c2aa6c300667a25ae6d52e
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSD11B2 CRIP1 FOXF2	3.68e-04	196	32	3	40e6900a0d56088a40d37ec312f53207ea952602
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSD11B2 CRIP1 FOXF2	3.68e-04	196	32	3	cb5860f580b477bfa52b22cdc21b808e1371e6e0
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_prolif\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSD11B2 CRIP1 FOXF2	3.68e-04	196	32	3	9a420a4eb46cb554bec641726fea5398ff60f630
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM1-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	GLUL SEMA4A CYP19A1	3.68e-04	196	32	3	bcd274db4955ea76ca26267a272c7d1929db24f4
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM1\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GLUL SEMA4A CYP19A1	3.68e-04	196	32	3	80b9139d91dda4de69830d2d443859e047ab5503
ToppCell	facs-Skin-nan-18m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNS2 HOXC9 CRIP1	3.68e-04	196	32	3	81f9754567bbfa67edd304b9ef7b03e7bd9a3b52
ToppCell	Mild_COVID-19-Myeloid-MoAM1\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	GLUL SEMA4A CYP19A1	3.68e-04	196	32	3	ea3fbe81b4ecb6ccc8031f6d99da93c9f9f8c1aa
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSD11B2 CRIP1 FOXF2	3.68e-04	196	32	3	73f029d2b276776d6c24356b14c6592c9cb74bd5
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSD11B2 CRIP1 FOXF2	3.68e-04	196	32	3	0b247cf981981ae61aca5de82ef687e8d783c9ef
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM1\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	GLUL SEMA4A CYP19A1	3.68e-04	196	32	3	7c8aa5853d7096628e35af665097c0299c329753
ToppCell	BAL-Mild-Myeloid-MoAM-MoAM1-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GLUL SEMA4A CYP19A1	3.68e-04	196	32	3	f60b220ed117bcc33e0f7bbf5b53d3b1422ebaca
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	DIO3 HOXB6 FOXF2	3.73e-04	197	32	3	16758f181ef07c60aee63072e1da9572c5c85414
ToppCell	tumor_Lung-T/NK_cells-CD4+_Th\|T/NK_cells / Location, Cell class and cell subclass	SEMA4A CRIP1 NFKB2	3.73e-04	197	32	3	0379d67beeba5864b5ffe5d282643204a112754f
ToppCell	(4)_Endothelial_cells-(41)_EC-arteriolar\|(4)_Endothelial_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	GLUL SEMA7A CRIP1	3.73e-04	197	32	3	482e3f8926880afed88ed37553ed2b5ed58b8c99
ToppCell	P03-Mesenchymal-myocytic_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	HOXB6 CRIP1 FOXF2	3.73e-04	197	32	3	079db904a08743b3c555cb7b3f5fb5c978dde25a
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSD11B2 CRIP1 FOXF2	3.73e-04	197	32	3	12370ee857fddf1cf26196b23c21b68dcea48eb3
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-mature_enterocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV4 ERBB3 CRIP1	3.73e-04	197	32	3	755a53d4206354583bc5b76b63a0b1c9892b7382
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSD11B2 CRIP1 FOXF2	3.73e-04	197	32	3	af819b0561c8db582c5b466d804153d69d3297e0
ToppCell	BAL-Mild-Myeloid-MoAM\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	GLUL SEMA4A CYP19A1	3.73e-04	197	32	3	0f40dd3530eb8d02e79b32f942efe3b65b8f6ee6
ToppCell	11.5-Distal-Epithelial\|Distal / Age, Tissue, Lineage and Cell class	ERBB3 HSD11B2 CRIP1	3.73e-04	197	32	3	ae9505ae7e6c5e8c280f9bfb1ba79ab5bd8895e3
ToppCell	BAL-Mild-Myeloid-MoAM\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	GLUL SEMA4A CYP19A1	3.73e-04	197	32	3	a6aa5991d566c28440f7e24a30933e69669064f2
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV4 ERBB3 CRIP1	3.79e-04	198	32	3	ad9fb53cd216af9bc9998d6b3bd0255b45e0dbfb
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.0.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLUL HOXB6 CRIP1	3.79e-04	198	32	3	a41d0a6e5f9f30a48bb7fed431a3e8257f62f955
ToppCell	distal-Hematologic-Alveolar_Macrophage-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GLUL HOXB6 CRIP1	3.79e-04	198	32	3	cd56124ff98a194ec030588dac684535a31cb5e4
ToppCell	3'_v3-GI_small-bowel-Mast-Mast_cells\|GI_small-bowel / Manually curated celltypes from each tissue	GLUL HOXB6 SEMA4A	3.79e-04	198	32	3	920d2e6603a06c2e8dcb6be127202d222c662bca
ToppCell	mLN-T_cell-Th17\|T_cell / Region, Cell class and subclass	SEMA4A CRIP1 NFKB2	3.79e-04	198	32	3	efdc9515dd9fb20ef9c8ddc106d88cbdde7d6ea2
ToppCell	distal-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GLUL HOXB6 CRIP1	3.79e-04	198	32	3	6aef5f5f89b508b214e1ab1876a743dedda0553b
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV4 ERBB3 CRIP1	3.79e-04	198	32	3	7c4993be089979e79ca1a160c0c4059c422eac6d
ToppCell	3'_v3-GI_small-bowel-Mast\|GI_small-bowel / Manually curated celltypes from each tissue	GLUL HOXB6 SEMA4A	3.79e-04	198	32	3	807e3ed34739eca159dd0970f884b073e588c649
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ETV4 ERBB3 CRIP1	3.79e-04	198	32	3	edf3e1c2be9df5690492b9c8fc25e7e48ed5c92c
ToppCell	Caecum-T_cell-Th1\|T_cell / Region, Cell class and subclass	TNS2 MED12 CRIP1	3.85e-04	199	32	3	13a80e6d3cf9c831edbe0644545071153e35f82b
ToppCell	(04)_Interm._basal>secr.\|World / shred by cell type by condition	GLUL ERBB3 HSD11B2	3.85e-04	199	32	3	ed399244433f781fc291a9bff16825b8a3ca294f
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GLIS1 ATRNL1 FOXF2	3.90e-04	200	32	3	fb53be20392a8309a7393774c774a1b1aec6e676
Disease	Alcohol withdrawal syndrome	GLUL CYP19A1	2.98e-05	8	31	2	C0236663
Disease	Neoplasm Metastasis	ETV4 DIO3 ERBB3 CYP19A1	7.66e-05	217	31	4	C0027627
Disease	Malignant neoplasm of breast	ETV4 DIO3 ERBB3 AKAP8 PDCD6 MED12 CYP19A1	1.01e-04	1074	31	7	C0006142
Disease	Mammary Neoplasms, Human	ETV4 DIO3 ERBB3 MED12 CYP19A1	2.03e-04	525	31	5	C1257931
Disease	Mammary Carcinoma, Human	ETV4 DIO3 ERBB3 MED12 CYP19A1	2.03e-04	525	31	5	C4704874
Disease	Mammary Neoplasms	ETV4 DIO3 ERBB3 MED12 CYP19A1	2.06e-04	527	31	5	C1458155
Disease	Breast Carcinoma	ETV4 DIO3 ERBB3 MED12 CYP19A1	2.27e-04	538	31	5	C0678222
Disease	Nephrotic Syndrome	TNS2 HSD11B2	3.69e-04	27	31	2	C0027726
Disease	obesity (implicated_via_orthology)	GLUL ETV4 MED12	1.48e-03	215	31	3	DOID:9970 (implicated_via_orthology)
Disease	Major Depressive Disorder	ERBB3 AKAP8 MED12	2.09e-03	243	31	3	C1269683

Protein segments in the cluster

Peptide	Gene	Start	Entry
GPGGDYAAMGACPAS	ERBB3	1271	P21860
MQGAGGYDSTMPYGC	AKAP8	261	O43823
GYDSTMPYGCGRSQP	AKAP8	266	O43823
SGPSPRRMGGYYAGE	AJM1	316	C9J069
AGDMPYPCLGAYGTS	HSD11B2	221	P80365
CYAAMFGPKGFGRGG	CRIP1	56	P50238
SGPSPGDGAMGYGYE	ETV4	286	P43268
PYELCGGMAYCGPQV	POU5F1B	66	Q06416
GPGEGRSYPDYMYGS	HOXC9	131	P31274
GAGNYGMCGRAYSPR	MCCC2	446	Q9HCC0
SGTIMYQGGRGPDGY	DIO3	266	P55073
MAAYSYRPGPGAGPG	PDCD6	1	O75340
MAEYYRPGPAGSGGC	MED12	201	Q93074
DYGMGPGRSGPYGVT	MED12	1801	Q93074
MASYPYRQGCPGAAG	PEF1	1	Q9UBV8
PAGGGYGRAAPCDYG	HOXB6	61	P17509
YGCGTAAFPYPMMHG	C5orf24	156	Q7Z6I8
YEGTSSIPGPGYCMG	CYP19A1	41	P11511
QDCMPGYYGDPTNGG	ATRNL1	1041	Q5VV63
PYGDCYRMAEPAAGG	GLIS1	526	Q8NBF1
PAGYLLYCPCMGRFG	POFUT1	31	Q9H488
GGYGGLDMMPAGYDA	FOXF2	241	Q12947
GPQGPYYCGVGADRA	GLUL	156	P15104
DYMYSAQGNGGGPPR	SCYL1	161	Q96KG9
AGGGGQGPMPRVRYY	SEMA4A	31	Q9H3S1
MSASPSGYGGLPYGA	SOX1	266	O00570
YGGGCHGCLMSRDPY	SEMA7A	496	O75326
PGLDYGGYEPMDSGG	USP24	46	Q9UPU5
RCMYPGGQGDYAGFP	PPIP5K2	531	O43314
TMCPEGRYGHPGYPA	TNS2	771	Q63HR2
AFRCMYPGGQGDYAG	PPIP5K1	541	Q6PFW1
GPDGDFSSPGSGCYM	ZAN	246	Q9Y493
GMDRDYGPGSYGGMD	ZNF326	21	Q5BKZ1
SPYQSGAGPMGCYPG	NFKB2	386	Q00653