Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	D-glucose binding	HK3 GYS2 UGP2	7.90e-05	14	123	3	GO:0005536
Domain	EIF3C_N_dom	EIF3CL EIF3C	4.30e-05	2	123	2	IPR008905
Domain	eIF-3c_N	EIF3CL EIF3C	4.30e-05	2	123	2	PF05470
Domain	EIF3C	EIF3CL EIF3C	4.30e-05	2	123	2	IPR027516
Domain	LY	LRP1B LRP2 ROS1	1.20e-04	15	123	3	SM00135
Domain	LDLR_classB_rpt	LRP1B LRP2 ROS1	1.20e-04	15	123	3	IPR000033
Domain	-	APEH LRP1B LRP2 ROS1	1.23e-04	39	123	4	2.120.10.30
Domain	Ryanodine_rcpt	RYR1 RYR2	1.29e-04	3	123	2	IPR003032
Domain	Ryanrecept_TM4-6	RYR1 RYR2	1.29e-04	3	123	2	IPR009460
Domain	RyR	RYR1 RYR2	1.29e-04	3	123	2	PF02026
Domain	RR_TM4-6	RYR1 RYR2	1.29e-04	3	123	2	PF06459
Domain	Ryan_recept	RYR1 RYR2	1.29e-04	3	123	2	IPR013333
Domain	Importin-beta_N	IPO5 XPO6 XPOT	1.77e-04	17	123	3	IPR001494
Domain	6-blade_b-propeller_TolB-like	APEH LRP1B LRP2 ROS1	2.36e-04	46	123	4	IPR011042
Domain	ER_TARGET	ERP44 UGGT1 P3H1 RCN3	2.57e-04	47	123	4	PS00014
Domain	RIH_assoc-dom	RYR1 RYR2	6.34e-04	6	123	2	IPR013662
Domain	Xpo1	XPO6 XPOT	6.34e-04	6	123	2	PF08389
Domain	Ins145_P3_rec	RYR1 RYR2	6.34e-04	6	123	2	PF08709
Domain	RIH_assoc	RYR1 RYR2	6.34e-04	6	123	2	PF08454
Domain	RIH_dom	RYR1 RYR2	6.34e-04	6	123	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR2	6.34e-04	6	123	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR2	6.34e-04	6	123	2	IPR015925
Domain	-	RYR1 RYR2	6.34e-04	6	123	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR2	6.34e-04	6	123	2	PF01365
Domain	Exportin-1/Importin-b-like	XPO6 XPOT	6.34e-04	6	123	2	IPR013598
Domain	Calx_beta	FREM3 SLC8A3	1.17e-03	8	123	2	SM00237
Domain	EF-hand_8	RYR1 RYR2 RCN3	1.44e-03	34	123	3	PF13833
Domain	Calx_beta	FREM3 SLC8A3	1.50e-03	9	123	2	IPR003644
Domain	Cl-channel_core	CLCN3 CLCN4	1.50e-03	9	123	2	IPR014743
Domain	-	CLCN3 CLCN4	1.50e-03	9	123	2	1.10.3080.10
Domain	Voltage_CLC	CLCN3 CLCN4	1.50e-03	9	123	2	PF00654
Domain	Cl-channel_volt-gated	CLCN3 CLCN4	1.50e-03	9	123	2	IPR001807
Domain	Calx-beta	FREM3 SLC8A3	1.50e-03	9	123	2	PF03160
Domain	MIR	RYR1 RYR2	1.87e-03	10	123	2	PF02815
Domain	MIR_motif	RYR1 RYR2	1.87e-03	10	123	2	IPR016093
Domain	Rap_GAP	RALGAPA1 RALGAPA2	1.87e-03	10	123	2	PF02145
Domain	MIR	RYR1 RYR2	1.87e-03	10	123	2	PS50919
Domain	MIR	RYR1 RYR2	1.87e-03	10	123	2	SM00472
Domain	Rap_GAP_dom	RALGAPA1 RALGAPA2	2.28e-03	11	123	2	IPR000331
Domain	RAPGAP	RALGAPA1 RALGAPA2	2.28e-03	11	123	2	PS50085
Domain	Peptidase_S9	APEH DPP8	2.28e-03	11	123	2	PF00326
Domain	Peptidase_S9	APEH DPP8	2.28e-03	11	123	2	IPR001375
Domain	ELM2_dom	MIER3 MIER1	3.20e-03	13	123	2	IPR000949
Domain	ELM2	MIER3 MIER1	3.20e-03	13	123	2	PF01448
Domain	ELM2	MIER3 MIER1	3.20e-03	13	123	2	PS51156
Domain	ELM2	MIER3 MIER1	3.20e-03	13	123	2	SM01189
Domain	IMPORTIN_B_NT	IPO5 XPO6	3.72e-03	14	123	2	PS50166
Domain	Ldl_recept_b	LRP1B LRP2	3.72e-03	14	123	2	PF00058
Domain	LDLRB	LRP1B LRP2	3.72e-03	14	123	2	PS51120
Domain	IBN_N	XPO6 XPOT	4.27e-03	15	123	2	PF03810
Domain	SANT	BDP1 MIER3 MIER1	4.36e-03	50	123	3	SM00717
Domain	CBS	CLCN3 CLCN4	4.86e-03	16	123	2	SM00116
Domain	IBN_N	XPO6 XPOT	4.86e-03	16	123	2	SM00913
Domain	PINT	EIF3CL EIF3C	4.86e-03	16	123	2	SM00088
Domain	SANT/Myb	BDP1 MIER3 MIER1	4.87e-03	52	123	3	IPR001005
Domain	PCI_dom	EIF3CL EIF3C	5.48e-03	17	123	2	IPR000717
Domain	PCI	EIF3CL EIF3C	5.48e-03	17	123	2	PF01399
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	THOC1 AFTPH HUWE1 RFX7 MIER1 CIC EIF3CL ZC3H4 XPO6 CBFA2T2 EIF3C CTNNA1 OGA MAP4K4 MED13 ZMYM4 TP53BP1	2.24e-09	774	123	17	15302935
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	IPO5 RPGRIP1L NUP107 L1TD1 HUWE1 CCDC141 GTF3C5 ZC3H4 CTNNA1 HYDIN ZMYM4 TP53BP1	1.17e-07	469	123	12	27634302
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	THOC1 IPO5 RIOK1 ERP44 NUP107 UGGT1 GARS1 KIAA0586 HUWE1 DIS3 GTF3C5 EIF3CL MRPL4 PNPLA8 EIF3C MAP4K4 SEC23A SYNCRIP XPOT NPAS2	1.40e-07	1425	123	20	30948266
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	IPO5 ERP44 UGGT1 GARS1 APEH HUWE1 DPP8 DIS3 EIF3CL P3H1 UGP2 EIF3C CTNNA1 HERC1 OGA PRPF39 SEC23A SFN SYNCRIP XPOT	1.96e-07	1455	123	20	22863883
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	RAF1 CASP8AP2 ERP44 NUP107 HUWE1 CIC GTF3C5 EIF4ENIF1 LRP2 UTRN ZMYM4	3.06e-07	418	123	11	34709266
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	RALGAPA1 RIOK1 RPGRIP1L ERP44 UGGT1 HUWE1 GTF3C5 EIF4ENIF1 AKAP13 CEP295 PRR14L TTC13 PATJ MAP4K4	3.51e-07	733	123	14	34672954
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 PITPNM2 CASP8AP2 PIEZO1 LRRK1 MIER1 DIS3 ZC3H4 OGA MAP4K4 MED13 ZMYM4	4.22e-07	529	123	12	14621295
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	IPO5 RAF1 ERP44 NUP107 UGGT1 GARS1 HUWE1 DIS3 GTF3C5 EIF3CL MRPL4 EIF3C OGA PRPF39 SEC23A SFN SYNCRIP XPOT	4.76e-07	1257	123	18	37317656
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RAF1 RIOK1 RPGRIP1L NUP107 GARS1 STYXL2 DPP8 DIS3 GTF3C5 EIF3CL ASAP2 BBX EIF4ENIF1 XPO6 CTNNA1 RSPH9 TP53BP1 SYNCRIP	9.70e-07	1321	123	18	27173435
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	IPO5 UGGT1 GARS1 ALDH1L1 HUWE1 RYR1 AKAP13 CTNNA1 UTRN HYDIN SEC23A SFN SYNCRIP XPOT	1.10e-06	807	123	14	30575818
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	IPO5 NUP107 UGGT1 GARS1 APEH LRRK1 CTNNA1 PRPF39 SEC23A TP53BP1 SYNCRIP	1.57e-06	494	123	11	26831064
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	IPO5 RAF1 ERP44 UGGT1 HUWE1 DIS3 PTPRD PRKAB1 TTC13 EIF3C CTNNA1 UTRN SFN SYNCRIP XPOT	1.93e-06	974	123	15	28675297
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	RAF1 AFTPH CCDC141 CIC ASAP2 EIF4ENIF1 CBFA2T2 AKAP13 PATJ SFN	3.26e-06	430	123	10	35044719
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	RALGAPA1 RPGRIP1L NUP107 ZNF174 UGGT1 HUWE1 CIC PTPRD P3H1 EIF3C CTNNA1 FBXO33 HERC1 UTRN XPOT	4.74e-06	1049	123	15	27880917
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	RALGAPA1 CASP8AP2 AFTPH NUP107 PIEZO1 UGGT1 APEH MRPL4 P3H1 MRPS6 AKAP13 PNPLA8 TTC13 CTNNA1 OGA MAP4K4 TP53BP1 SYNCRIP	5.09e-06	1487	123	18	33957083
Pubmed	Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.	HK3 ERP44 UGGT1 DIS3 PTPRD TTC13 HERC1 XPOT	8.41e-06	285	123	8	32838362
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	THOC1 IPO5 RAF1 NUP107 GARS1 APEH HUWE1 RFX7 DIS3 AXIN1 MRPL4 CTNNA1 PATJ MED13 SFN SYNCRIP	8.74e-06	1247	123	16	27684187
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	IPO5 ESRRG DGKD CCDC141 RYR1 UGP2 EIF3C UTRN MED13 ZMYM4	1.15e-05	497	123	10	23414517
Pubmed	Human transcription factor protein interaction networks.	NUP107 YY2 RFX7 MIER1 CIC MRPL4 BBX EIF4ENIF1 LRP2 MRPS6 EIF3C HERC1 ZMYM4 TP53BP1 SFN SYNCRIP XPOT	1.20e-05	1429	123	17	35140242
Pubmed	Uncoupling endosomal CLC chloride/proton exchange causes severe neurodegeneration.	CLCN3 CLCN4	1.24e-05	2	123	2	32118314
Pubmed	Three-Dimensional Matrix Stiffness Activates the Piezo1-AMPK-Autophagy Axis to Regulate the Cellular Osteogenic Differentiation.	PIEZO1 PRKAB1	1.24e-05	2	123	2	37428711
Pubmed	Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.	RYR1 RYR2	1.24e-05	2	123	2	17259277
Pubmed	Preferential association with ClC-3 permits sorting of ClC-4 into endosomal compartments.	CLCN3 CLCN4	1.24e-05	2	123	2	28972156
Pubmed	Ryanodine receptor oligomeric interaction: identification of a putative binding region.	RYR1 RYR2	1.24e-05	2	123	2	14722100
Pubmed	Structural and functional interactions within ryanodine receptor.	RYR1 RYR2	1.24e-05	2	123	2	26009179
Pubmed	EIF3C Promotes Lung Cancer Tumorigenesis by Regulating the APP/HSPA1A/LMNB1 Axis.	EIF3CL EIF3C	1.24e-05	2	123	2	36157221
Pubmed	Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.	RYR1 RYR2	1.24e-05	2	123	2	32899693
Pubmed	Recent advances in understanding the ryanodine receptor calcium release channels and their role in calcium signalling.	RYR1 RYR2	1.24e-05	2	123	2	30542613
Pubmed	Ryanodine receptors are expressed and functionally active in mouse spermatogenic cells and their inhibition interferes with spermatogonial differentiation.	RYR1 RYR2	1.24e-05	2	123	2	15280431
Pubmed	Expression of the ryanodine receptor isoforms in immune cells.	RYR1 RYR2	1.24e-05	2	123	2	11673493
Pubmed	B-lymphocytes from malignant hyperthermia-susceptible patients have an increased sensitivity to skeletal muscle ryanodine receptor activators.	RYR1 RYR2	1.24e-05	2	123	2	11673462
Pubmed	Inhibition of ubiquitin-specific protease 13-mediated degradation of Raf1 kinase by Spautin-1 has opposing effects in naïve and primed pluripotent stem cells.	RAF1 USP13	1.24e-05	2	123	2	34688658
Pubmed	Crystal structures of wild type and disease mutant forms of the ryanodine receptor SPRY2 domain.	RYR1 RYR2	1.24e-05	2	123	2	25370123
Pubmed	Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.	RYR1 RYR2	1.24e-05	2	123	2	15033925
Pubmed	Thermodynamics of calmodulin binding to cardiac and skeletal muscle ryanodine receptor ion channels.	RYR1 RYR2	1.24e-05	2	123	2	18618700
Pubmed	The E3 ubiquitin ligase HERC1 controls the ERK signaling pathway targeting C-RAF for degradation.	RAF1 HERC1	1.24e-05	2	123	2	30140388
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	IPO5 RAF1 RIOK1 UGGT1 GARS1 HUWE1 GTF3C5 EIF3CL ZC3H4 UGP2 MRPS6 PATJ OGA SEC23A SYNCRIP	1.39e-05	1149	123	15	35446349
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	THOC1 IPO5 ERP44 NUP107 UGGT1 HUWE1 GTF3C5 ZC3H4 EIF3C CTNNA1 MAP4K4 UTRN SEC23A SYNCRIP	1.66e-05	1024	123	14	24711643
Pubmed	Systematic identification of factors for provirus silencing in embryonic stem cells.	HUWE1 EIF3CL EIF3C CTNNA1 SEC23A TP53BP1	1.83e-05	153	123	6	26365490
Pubmed	Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1.	THOC1 XPO6 ZMYM4 TP53BP1	1.98e-05	45	123	4	33596420
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	IPO5 RAF1 RPGRIP1L NUP107 GARS1 HUWE1 MRPL4 EIF4ENIF1 ZC3H4 LRP2 MRPS6 PNPLA8 TTC13 HERC1 TRMT5 SEC23A SYNCRIP	2.15e-05	1496	123	17	32877691
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	IPO5 NUP107 UGGT1 HUWE1 DIS3 CTNNA1 UTRN SEC23A TP53BP1 SYNCRIP XPOT	2.17e-05	653	123	11	22586326
Pubmed	Tagging genes with cassette-exchange sites.	MAPK1IP1L UGGT1 RFX7 EIF3CL AKAP13 EIF3C ZMYM4 XPOT	2.69e-05	335	123	8	15741177
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	HK3 ERP44 UGGT1 HUWE1 MIER1 DIS3 RPS6KC1 LRP2 CEP295 HERC1 PATJ UTRN TP53BP1 XPOT	3.09e-05	1084	123	14	11544199
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	IPO5 ERP44 UGGT1 HUWE1 EIF3CL EIF3C SEC23A TP53BP1	3.24e-05	344	123	8	30333137
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	RPGRIP1L ERP44 BPIFB1 TMC3 MIER1 GTF3C5 BBX PTPRD GYS2 PRKAB1 FBXO33 HERC1 KLHL18 SEC23A PLXNB3	3.43e-05	1242	123	15	30973865
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR2	3.71e-05	3	123	2	18403125
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR2	3.71e-05	3	123	2	18434746
Pubmed	Tuberous sclerosis tumor suppressor complex-like complexes act as GTPase-activating proteins for Ral GTPases.	RALGAPA1 RALGAPA2	3.71e-05	3	123	2	19520869
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR2	3.71e-05	3	123	2	9204703
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR2	3.71e-05	3	123	2	7876312
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR2	3.71e-05	3	123	2	21881589
Pubmed	Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells.	RYR1 RYR2	3.71e-05	3	123	2	24123915
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR2	3.71e-05	3	123	2	12213830
Pubmed	Dopamine D1 receptor signaling system regulates ryanodine receptor expression in ethanol physical dependence.	RYR1 RYR2	3.71e-05	3	123	2	23278119
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR2	3.71e-05	3	123	2	9242641
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR2	3.71e-05	3	123	2	22948152
Pubmed	Direct association of the reticulon protein RTN1A with the ryanodine receptor 2 in neurons.	RYR1 RYR2	3.71e-05	3	123	2	23454728
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR2	3.71e-05	3	123	2	10788707
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR2	3.71e-05	3	123	2	25239916
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR2	3.71e-05	3	123	2	7621815
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR2	3.71e-05	3	123	2	18643873
Pubmed	Identification of mutations in the cardiac ryanodine receptor gene in families affected with arrhythmogenic right ventricular cardiomyopathy type 2 (ARVD2).	RYR1 RYR2	3.71e-05	3	123	2	11159936
Pubmed	Intracellular calcium release channel expression during embryogenesis.	RYR1 RYR2	3.71e-05	3	123	2	9986730
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR2	3.71e-05	3	123	2	10473538
Pubmed	Chromosomal localization of murine ryanodine receptor genes RYR1, RYR2, and RYR3 by in situ hybridization.	RYR1 RYR2	3.71e-05	3	123	2	7959768
Pubmed	The organization of proteins in the human red blood cell membrane. A review.	RYR1 RYR2	3.71e-05	3	123	2	4600883
Pubmed	Regulation of mouse egg activation: presence of ryanodine receptors and effects of microinjected ryanodine and cyclic ADP ribose on uninseminated and inseminated eggs.	RYR1 RYR2	3.71e-05	3	123	2	7635066
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PITPNM2 PIEZO1 APEH LRRK1 HUWE1 RALGAPA2 CIC RYR1 ANO8 EIF4ENIF1 XPO6 AKAP13 HERC1 MED13	3.81e-05	1105	123	14	35748872
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BDP1 CASP8AP2 RPGRIP1L NUP107 HUWE1 DIS3 CIC PATJ ZMYM4 TP53BP1	4.80e-05	588	123	10	38580884
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	IPO5 USP13 APEH HUWE1 LRP1B PTPRD LRP2 EIF3C CTNNA1 MAP4K4 UTRN MED13 ZMYM4 PLXNB3 XPOT	5.04e-05	1285	123	15	35914814
Pubmed	LINKIN, a new transmembrane protein necessary for cell adhesion.	ERP44 UGGT1 APEH DIS3 GTF3C5 CTNNA1 PRPF39 SEC23A SYNCRIP	5.53e-05	480	123	9	25437307
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	IPO5 USP13 ERP44 HUWE1 DIS3 P3H1 EIF3C OGA MAP4K4 UTRN KLHL18 ZMYM4 TP53BP1	5.94e-05	1005	123	13	19615732
Pubmed	Blocking an N-terminal acetylation-dependent protein interaction inhibits an E3 ligase.	IPO5 RIOK1 ERP44 UGGT1 GARS1 HUWE1 EIF3CL KLHL18 SYNCRIP	6.99e-05	495	123	9	28581483
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	BDP1 RIOK1 ALDH1L1 ZC3H4 CTNNA1 HERC1 MAP4K4 HYDIN XPOT	7.21e-05	497	123	9	36774506
Pubmed	A glutathione deficit alters dopamine modulation of L-type calcium channels via D2 and ryanodine receptors in neurons.	RYR1 RYR2	7.41e-05	4	123	2	18206662
Pubmed	Increase of ryanodine receptors by dopamine D1 receptors is negatively regulated by γ-aminobutyric acid type B receptors in primary cultures of mouse cerebral cortical neurons.	RYR1 RYR2	7.41e-05	4	123	2	22504960
Pubmed	Role of ClC-5 in renal endocytosis is unique among ClC exchangers and does not require PY-motif-dependent ubiquitylation.	CLCN3 CLCN4	7.41e-05	4	123	2	20351103
Pubmed	Interaction between the Ret finger protein and the Int-6 gene product and co-localisation into nuclear bodies.	EIF3CL EIF3C	7.41e-05	4	123	2	10504338
Pubmed	Calmodulin modulates the termination threshold for cardiac ryanodine receptor-mediated Ca2+ release.	RYR1 RYR2	7.41e-05	4	123	2	23992453
Pubmed	Ryanodine receptor calcium release channels: lessons from structure-function studies.	RYR1 RYR2	7.41e-05	4	123	2	23413940
Pubmed	Requirement for the ryanodine receptor type 3 for efficient contraction in neonatal skeletal muscles.	RYR1 RYR2	7.41e-05	4	123	2	9384575
Pubmed	Partial cloning and differential expression of ryanodine receptor/calcium-release channel genes in human tissues including the hippocampus and cerebellum.	RYR1 RYR2	7.41e-05	4	123	2	9607712
Pubmed	S100A1 Protein Does Not Compete with Calmodulin for Ryanodine Receptor Binding but Structurally Alters the Ryanodine Receptor·Calmodulin Complex.	RYR1 RYR2	7.41e-05	4	123	2	27226555
Pubmed	HUWE1 is a molecular link controlling RAF-1 activity supported by the Shoc2 scaffold.	RAF1 HUWE1	7.41e-05	4	123	2	25022756
Pubmed	Hypoxia differently modulates gene expression of inositol 1,4,5-trisphosphate receptors in mouse kidney and HEK 293 cell line.	RYR1 RYR2	7.41e-05	4	123	2	19120137
Pubmed	FKBP binding characteristics of cardiac microsomes from diverse vertebrates.	RYR1 RYR2	7.41e-05	4	123	2	11237759
Pubmed	Conserved and divergent functions of Nfix in skeletal muscle development during vertebrate evolution.	RYR1 RYR2	7.41e-05	4	123	2	23482488
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	AFTPH NUP107 HUWE1 EIF3CL ZC3H4 AKAP13 EIF3C TP53BP1 SFN	7.90e-05	503	123	9	16964243
Pubmed	Loci associated with N-glycosylation of human immunoglobulin G show pleiotropy with autoimmune diseases and haematological cancers.	CD207 LRRC4C RALGAPA2 LRP1B RYR2 SLC8A3	7.93e-05	199	123	6	23382691
Pubmed	Integrative analysis of kinase networks in TRAIL-induced apoptosis provides a source of potential targets for combination therapy.	RAF1 RIOK1 RPS6KC1 PRKAB1 EIF3C CTNNA1 MAP4K4 SFN	9.46e-05	401	123	8	25852190
Pubmed	∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.	UGGT1 GARS1 HUWE1 CTNNA1 PRPF39 SEC23A TP53BP1 MX2 SFN XPOT	1.06e-04	647	123	10	26618866
Pubmed	Role of leaky neuronal ryanodine receptors in stress-induced cognitive dysfunction.	RYR1 RYR2	1.23e-04	5	123	2	22939628
Pubmed	Intracellular calcium-release channels: regulators of cell life and death.	RYR1 RYR2	1.23e-04	5	123	2	9124414
Pubmed	Presenilins regulate calcium homeostasis and presynaptic function via ryanodine receptors in hippocampal neurons.	RYR1 RYR2	1.23e-04	5	123	2	23918386
Pubmed	An essential role for ClC-4 in transferrin receptor function revealed in studies of fibroblasts derived from Clcn4-null mice.	CLCN3 CLCN4	1.23e-04	5	123	2	19339555
Pubmed	Protein kinase C-epsilon regulates local calcium signaling in airway smooth muscle cells.	RYR1 RYR2	1.23e-04	5	123	2	19011160
Pubmed	Differential HDAC1 and 2 Recruitment by Members of the MIER Family.	MIER3 MIER1	1.23e-04	5	123	2	28046085
Pubmed	CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity.	IPO5 ERP44 UGGT1 HUWE1 LRP2 TTC13 SYNCRIP XPOT	1.26e-04	418	123	8	35338135
Pubmed	Ankyrin repeats of ANKRA2 recognize a PxLPxL motif on the 3M syndrome protein CCDC8.	HUWE1 RFX7 GTF3C5	1.33e-04	28	123	3	25752541
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR2	6.23e-05	3	83	2	287
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	PPP1R21 RPGRIP1L RYR1 AXIN1 PPP1R1B HYDIN	1.85e-04	181	83	6	694
GeneFamily	Exportins	XPO6 XPOT	4.31e-04	7	83	2	547
GeneFamily	Chloride voltage-gated channels	CLCN3 CLCN4	9.15e-04	10	83	2	302
GeneFamily	Low density lipoprotein receptors	LRP1B LRP2	1.57e-03	13	83	2	634
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	BDP1 MIER3 MIER1	1.85e-03	53	83	3	532
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	RALGAPA1 SLC9A9 RPGRIP1L RFX7 RALGAPA2 PRR14L HERC1 MAP4K4 UTRN KLHL18 MED13	9.33e-10	180	123	11	M8239
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500	RALGAPA1 ESRRG DGKD HUWE1 CLCN3 AKAP13 PRPF39 MED13 SYNCRIP	2.31e-06	201	121	9	gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlas	DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k-means-cluster#3_top-relative-expression-ranked_1000	RALGAPA1 ESRRG DGKD HUWE1 CLCN3 PRPF39 MED13 SYNCRIP	2.60e-06	152	121	8	gudmap_developingKidney_e15.5_Proximal Tubules_1000_k3
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000	RALGAPA1 ESRRG DGKD HUWE1 CCDC141 CLCN3 AKAP13 PRPF39 UTRN MED13 SYNCRIP	1.12e-05	379	121	11	gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_1000	RALGAPA1 BDP1 ESRRG L1TD1 DGKD LRRK1 HUWE1 CCDC141 CLCN3 LRP2 ROS1 PATJ PRPF39 MED13 SYNCRIP	3.47e-05	774	121	15	gudmap_developingKidney_e15.5_cortic collect duct_1000
CoexpressionAtlas	DevelopingKidney_e15.5_cortic collect duct_emap-28132_top-relative-expression-ranked_500	RALGAPA1 ESRRG HUWE1 CCDC141 CLCN3 LRP2 PATJ PRPF39 MED13 SYNCRIP	8.06e-05	390	121	10	gudmap_developingKidney_e15.5_cortic collect duct_500
CoexpressionAtlas	DevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500	RALGAPA1 ESRRG DGKD HUWE1 CLCN3 AKAP13 PATJ PRPF39 MED13 SYNCRIP	1.03e-04	402	121	10	gudmap_developingKidney_e15.5_anlage of loop of Henle_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_Urothelium_emap-28091_top-relative-expression-ranked_1000	SLC9A9 ESRRG DGKD LRRK1 CCDC141 PTPRD CLCN3 PLIN5 LRP2 PATJ PRPF39 UTRN MED13 SYNCRIP	1.52e-04	784	121	14	gudmap_developingLowerUrinaryTract_e15.5_urothelium_1000
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STK32B ESRRG ALDH1L1 PTPRD LRP2 PATJ HYDIN	7.84e-07	183	123	7	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC4C LRP1B RYR2 PTPRD LRP2 ROS1 HYDIN	8.13e-07	184	123	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	USP13 STK32B ESRRG ALDH1L1 LRP1B PLIN5 LTBP2	8.13e-07	184	123	7	e8238fe58f94b4f5700ab7f343fb06ea61e899a9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC4C LRP1B RYR2 PTPRD LRP2 ROS1 HYDIN	8.13e-07	184	123	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC4C LRP1B RYR2 PTPRD LRP2 ROS1 HYDIN	8.13e-07	184	123	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	RALGAPA1 HUWE1 HERC1 UTRN KLHL18 MED13 TP53BP1	9.39e-07	188	123	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	IPF-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	USP13 DGKD CCDC141 PPP1R1B LRP2 AKAP13 ROS1	9.39e-07	188	123	7	5f5fad2773e421760e67dbace23fd1f847a2e1e0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	USP13 STK32B ESRRG ALDH1L1 LRP1B PLIN5 LTBP2	1.01e-06	190	123	7	cc17ab84a9328124f146951c06be3eff9650d9fd
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PITPNM2 USP13 DGKD CCDC141 PTPRD ROS1 PATJ	1.16e-06	194	123	7	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	MUC16 BPIFB1 PATJ WDR49 RSPH9 HYDIN	3.98e-06	151	123	6	8216462e723fec2797387929dde095370947e10a
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	EIF3CL CEP295 EIF3C PATJ OGA CCDC191	7.09e-06	167	123	6	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC5_(CLDN11+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	USP13 CYP8B1 STK32B CCDC141 CLCN4 KIF17	1.05e-05	179	123	6	40c65e8623547aeb80f9cd2366e29072467ce069
ToppCell	COVID-19-kidney-PCT-S2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STK32B ESRRG ALDH1L1 PTPRD LRP2 PATJ	1.09e-05	180	123	6	358923e4228035a3e90e2957392089219e90dcd7
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	STK32B ESRRG ALDH1L1 LRP1B MRPS6 LTBP2	1.35e-05	187	123	6	b93cf4dfe8ffb89348ee7bccc9f284189f7240a2
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	CCDC141 SULT1A2 PPP1R1B TM7SF2 ROS1 SFN	1.35e-05	187	123	6	11670a85db87cbb3e78022a589632173604b0940
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STK32B ESRRG ALDH1L1 LRP1B LRP2 PATJ	1.35e-05	187	123	6	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	367C-Epithelial_cells-Epithelial-E_(AT2)\|367C / Donor, Lineage, Cell class and subclass (all cells)	CCDC141 SULT1A2 PPP1R1B TM7SF2 ROS1 SFN	1.35e-05	187	123	6	0277d4e54bd4d48f30241c2951a569209423fee8
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP13 DGKD CCDC141 PPP1R1B AKAP13 ROS1	1.62e-05	193	123	6	8646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	USP13 ESRRG DGKD RYR2 PATJ NPAS2	1.62e-05	193	123	6	dd5378a1ef8eb0eda9a3aae62f3c2f3a1402bda0
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STK32B ESRRG ALDH1L1 LRP1B LRP2 PATJ	1.62e-05	193	123	6	82e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RPGRIP1L MUC16 PLIN5 CCDC191 WDR49 HYDIN	1.66e-05	194	123	6	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	COVID-19-Heart-CM_2\|Heart / Disease (COVID-19 only), tissue and cell type	USP13 ESRRG CCDC141 RYR2 AKAP13 PATJ	1.71e-05	195	123	6	75fc81bddb246dca3b437fb60827b1d4fe416405
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP13 CCDC141 TM7SF2 LRP2 AKAP13 ROS1	1.76e-05	196	123	6	82b117be41f2e7d677a42d2a5198726eeccb16d0
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP13 CCDC141 TM7SF2 AKAP13 ROS1 SFN	1.76e-05	196	123	6	b1abecc0aafc09ca70a5fde624f2a998c4aa3341
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Serous\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ESRRG BPIFB1 ALDH1L1 PLIN5 PPP1R1B TM7SF2	1.81e-05	197	123	6	d3539607d5477f5dfd85f1fa99b74677c0fa8937
ToppCell	cellseq2-Epithelial-Epithelial_Glandular-Serous-Serous\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ESRRG BPIFB1 ALDH1L1 PLIN5 PPP1R1B TM7SF2	1.81e-05	197	123	6	40bd7c314ff5254d87737822078e7b9eaf23edf3
ToppCell	Parenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT2\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CCDC141 PPP1R1B TM7SF2 LRP2 ROS1 SFN	1.92e-05	199	123	6	fa5ddba3ac1ebe712cd4cdc3f20339f7c715d039
ToppCell	Biopsy_IPF-Epithelial-AT2\|Biopsy_IPF / Sample group, Lineage and Cell type	CCDC141 SULT1A2 PPP1R1B LRP2 ROS1 SFN	1.92e-05	199	123	6	c841d475703d3489161fb7904526bd7563d5fb0f
ToppCell	droplet-Liver-nan-3m-Myeloid-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC27A6 MIER3 DPP8 C3orf70 TP53BP1	2.74e-05	127	123	5	39fa20a55de3af1a62ab5dfa4877879db3935ac2
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	RPGRIP1L CYP8B1 YY2 LRRC4C TTC13	4.37e-05	140	123	5	af9efcbaeeae69fcdac4a15fa244728b65915564
ToppCell	Mild/Remission-B_naive-1\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	EIF3CL EIF3C PATJ OGA CCDC191	4.83e-05	143	123	5	bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell	Posterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	SLC26A4 ESRRG RALGAPA2 RYR1 HYDIN	5.00e-05	144	123	5	08005be9e3367f78ef27e125d9cce5ca53f4bd2d
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|367C / Donor, Lineage, Cell class and subclass (all cells)	BDP1 NUP107 KIAA0586 DPP8 XPO6	5.88e-05	149	123	5	41f28138bde45d0b814e116837e5a32b5e80d54a
ToppCell	NS-moderate-d_07-13-Epithelial-FOXN4+\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	USP13 RPGRIP1L CEP295 WDR49 HYDIN	7.53e-05	157	123	5	410c9d74a2085179cfb39853cb6d330fa98c9c1b
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRG LRP1B RYR2 LRP2 HYDIN	8.23e-05	160	123	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ESRRG LRP1B RYR2 LRP2 HYDIN	8.23e-05	160	123	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	BAL-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	MUC16 RYR1 FAM151B CLCN3 WDR49	8.48e-05	161	123	5	7a6e8ed0b5d999efce8945d8083ab01d71be9a92
ToppCell	wk_08-11-Mesenchymal-Myofibro_&_SMC-Late_airway_SMC\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	RALGAPA1 PITPNM2 MIER3 LRP1B C3orf70	8.98e-05	163	123	5	1e8730d75cccf7292010683ab4e81a69d8e3bfa9
ToppCell	facs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ESRRG LRRC4C INSC LRP2 PLXNB3	9.25e-05	164	123	5	3caf4cdaa0164907893fea61e251fd8b5fa926e4
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B RYR2 LRP2 LTBP2 HYDIN	1.06e-04	169	123	5	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	droplet-Liver-nan-3m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC27A6 KIAA0586 LRRK1 C3orf70 RSPH9	1.16e-04	172	123	5	f814b6134ad608015765399d54cc1e5e1873ed34
ToppCell	droplet-Lung-LUNG-30m-Myeloid-Myeloid_Dendritic_Type_2\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC9A9 CYP8B1 CD207 BPIFB1 RYR1	1.16e-04	172	123	5	a5344760b10ecdc0101f78b93b8fc0f8107068c5
ToppCell	Mild/Remission-B_naive-8\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	DGKD OGA CCDC191 UTRN WDR49	1.19e-04	173	123	5	694d02c4d2dc2de4b344544f9124fec40fcf7d8f
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B RYR2 LRP2 LTBP2 HYDIN	1.19e-04	173	123	5	66f37c1437705734b20601656fa4aa1d92ca30be
ToppCell	facs-Diaphragm-Limb_Muscle-24m-Mesenchymal-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRP1B RYR2 LRP2 LTBP2 HYDIN	1.19e-04	173	123	5	649b08a409095592cccf31883be69c754411280d
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|kidney / Disease (COVID-19 only), tissue and cell type	ESRRG LRP1B LRP2 PATJ NPAS2	1.29e-04	176	123	5	36f77d878a53b30465b0dea8333a3865dba75613
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC26A4 CCDC141 RYR2 PPP1R1B LRP2	1.36e-04	178	123	5	76e71fff99cf64302e2e3c0d66dd8ba0ff13624e
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte-type_2_alveolar_epithelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC26A4 CCDC141 RYR2 PPP1R1B LRP2	1.36e-04	178	123	5	82f78ea1ea3ff3e2347cd8bc2f06e2a10e96f220
ToppCell	droplet-Lung-30m-Epithelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC26A4 CCDC141 RYR2 PPP1R1B LRP2	1.36e-04	178	123	5	5442bc52b8e902da1383f44d97a9f95e471a8d4d
ToppCell	droplet-Lung-30m-Epithelial-alveolar_epithelial-type_II_pneumocyte\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC26A4 CCDC141 RYR2 PPP1R1B LRP2	1.36e-04	178	123	5	523b286ebe0359c7f1902f28cbd71f452626fc0d
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP13 BPIFB1 ASAP2 WDR49 RSPH9	1.39e-04	179	123	5	d15182c668d7c37be8214cad9f1fe35d1409c9a1
ToppCell	5'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP13 BPIFB1 ASAP2 WDR49 RSPH9	1.39e-04	179	123	5	e22a275a7c0ed19113c833a75d6c49fcc19aa13a
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO1 RALGAPA2 CCDC141 PLIN5 UTRN	1.39e-04	179	123	5	abc6797bd3884aa75dca58fcb2523ee321243ab1
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PIEZO1 RALGAPA2 CCDC141 PLIN5 UTRN	1.39e-04	179	123	5	0b996d6e881f31e6b80d359f7caac70ecdeb9982
ToppCell	RA-11._Adipocyte\|RA / Chamber and Cluster_Paper	ALDH1L1 LRP1B PLIN5 GYS2 OGA	1.43e-04	180	123	5	d48a3d27357f7d184132a6805950f93080146b59
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	STK32B LRRC4C SLFN14 SLC8A3 ASAP2	1.47e-04	181	123	5	9dc0563453e24c9d1d975e2e0e1e272487e19908
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	STK32B LRRC4C SLFN14 SLC8A3 ASAP2	1.47e-04	181	123	5	14c2dd946e89ba578711c2d25935b6b3d319b701
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	STK32B LRRC4C SLFN14 SLC8A3 ASAP2	1.47e-04	181	123	5	c5843b89f3d362e236ff76c3279518a2fdfc1f75
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Hematopoietic-Megakaryocytic-Megakaryocyte-Mega\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	STK32B LRRC4C SLFN14 SLC8A3 ASAP2	1.47e-04	181	123	5	fcefb5902416c004631f4f8dd5c8f99fe3bd90bc
ToppCell	droplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LRRC4C INSC PATJ CATSPERG PLXNB3	1.51e-04	182	123	5	6fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	EIF3CL EIF3C PATJ OGA MX2	1.51e-04	182	123	5	877b6e611626628e709568747512f2827ebb2795
ToppCell	21-Trachea-Epithelial-Multiciliated_precursor\|Trachea / Age, Tissue, Lineage and Cell class	USP13 RPGRIP1L PPP1R1B WDR49 RSPH9	1.51e-04	182	123	5	6e35892fa959ee31591850ded8f1088195ddeb01
ToppCell	COVID-19-kidney-Distal_Epi_Doublet_(PCT)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ESRRG ALDH1L1 LRP1B LRP2 PATJ	1.51e-04	182	123	5	9d67717a6e13bcb54c1297a3e4e3abf4e51628a3
ToppCell	LA-11._Adipocyte\|World / Chamber and Cluster_Paper	ALDH1L1 LRP1B PLIN5 GYS2 OGA	1.54e-04	183	123	5	b177be283e1553fb1f69a346f1ba79ad00297fa2
ToppCell	LA-11._Adipocyte\|LA / Chamber and Cluster_Paper	ESRRG ALDH1L1 LRP1B PLIN5 OGA	1.54e-04	183	123	5	3f9011976782fa8aa95cdd6f00f07a91094d411b
ToppCell	E17.5-Mesenchymal-mesenchymal_fibroblast-mesothelial_cell_of_visceral_pleura\|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	MUC16 FREM3 LRP1B INSC RCN3	1.58e-04	184	123	5	607b55022de21ddb6a2d75e085df76df7abf6624
ToppCell	IPF-Epithelial-ATII\|IPF / Disease state, Lineage and Cell class	CCDC141 PPP1R1B LRP2 ROS1 SFN	1.63e-04	185	123	5	563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	SLC9A9 STK32B RYR1 NLN RCN3	1.63e-04	185	123	5	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	ESRRG MUC16 WDR49 RSPH9 HYDIN	1.63e-04	185	123	5	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	367C-Lymphocytic-NK_cells-NK_cell_B0\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	BDP1 NUP107 KIAA0586 DPP8 XPO6	1.67e-04	186	123	5	74c238759c5d3fd39127ec0060d0c2cb16b326d4
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	CCDC141 PPP1R1B LRP2 ROS1 SFN	1.67e-04	186	123	5	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP13 CCDC141 RYR2 PLIN5 PPP1R1B	1.67e-04	186	123	5	337f768cc43db2db96ba6495b076006b1a5b0331
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	DGKD CBFA2T2 MAP4K4 UTRN MED13	1.67e-04	186	123	5	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	facs-Heart-LA-24m-Mesenchymal-ventricular_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	USP13 CCDC141 RYR2 PLIN5 PPP1R1B	1.67e-04	186	123	5	e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	DGKD CBFA2T2 MAP4K4 UTRN MED13	1.67e-04	186	123	5	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PTPRD LRP2 PATJ HYDIN NPAS2	1.67e-04	186	123	5	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	LRRC4C CCDC141 AKAP13 ROS1 PATJ	1.71e-04	187	123	5	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	droplet-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ALDH1L1 ASAP2 INSC PPP1R1B PLXNB3	1.71e-04	187	123	5	8e8b147258982b359447add5027318f5b6d51963
ToppCell	COPD-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	USP13 DGKD CCDC141 AKAP13 ROS1	1.71e-04	187	123	5	030af361f8bdcd0aff4ec1922702833325cf74d8
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MUC16 BPIFB1 ASAP2 LRP2 PLXNB3	1.71e-04	187	123	5	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	USP13 STK32B ESRRG LRP1B LTBP2	1.75e-04	188	123	5	2ee64bc73a2251fd9f374be759b442cf4ed0d19e
ToppCell	RA-11._Adipocyte\|World / Chamber and Cluster_Paper	ALDH1L1 LRP1B PLIN5 GYS2 OGA	1.75e-04	188	123	5	4dac9d636e5cad4cda540b93d4bfed6b5732c880
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)\|368C / Donor, Lineage, Cell class and subclass (all cells)	CCDC141 TM7SF2 LRP2 ROS1 SFN	1.80e-04	189	123	5	6f2322d017b74a1757c81d6e06f50ead8c3dd0cc
ToppCell	RV-04._Ventricular_Cardiomyocyte_I\|RV / Chamber and Cluster_Paper	ESRRG CCDC141 RYR2 PATJ NPAS2	1.80e-04	189	123	5	9c1debd65c13d63fd4f3158917d621b44b714c26
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ESRRG CCDC141 RYR2 AKAP13 PATJ	1.80e-04	189	123	5	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	368C-Epithelial_cells-Epithelial-E_(AT2)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	CCDC141 TM7SF2 LRP2 ROS1 SFN	1.80e-04	189	123	5	926b5fa3064b501a57ba78583e8af33532add455
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	ESRRG CCDC141 RYR2 AKAP13 PATJ	1.84e-04	190	123	5	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal-Deuterosomal_L.0.3.4.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP13 MUC16 CEP295 WDR49 RSPH9	1.84e-04	190	123	5	0adb24dafa077156bbc73a8d8cbf3d9eeb6e08df
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A9 LRRK1 CCDC141 RYR1 RCN3	1.84e-04	190	123	5	788ff9d8888d2dd25b7e1d7e0e5d57751ce86f19
ToppCell	368C-Epithelial_cells\|368C / Donor, Lineage, Cell class and subclass (all cells)	CCDC141 TM7SF2 LRP2 ROS1 SFN	1.84e-04	190	123	5	459811e88d3001816c2d89034e0921c24918c17f
ToppCell	NS-moderate-d_16-33-Epithelial-FOXN4+\|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	USP13 RPGRIP1L ASAP2 CEP295 WDR49	1.84e-04	190	123	5	250ca4a605c1cccd77d23383e4fe6f91cf3609ba
ToppCell	3'-Airway_Nasal-Epithelial-Airway_ciliated-multi-ciliated_epithelial_cell-Deuterosomal\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	USP13 MUC16 CEP295 WDR49 RSPH9	1.84e-04	190	123	5	05455775845f4ded5c27e7b83242078d23162aaf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	STK32B ESRRG LRP1B MRPS6 LTBP2	1.84e-04	190	123	5	3dcadabbefe0128a5f30ab51234f049ab4d870c6
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	ESRRG CCDC141 RYR2 AKAP13 PATJ	1.84e-04	190	123	5	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|LV / Chamber and Cluster_Paper	ESRRG CCDC141 RYR2 AKAP13 PATJ	1.88e-04	191	123	5	25f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC9A9 STYXL2 LRRK1 CCDC141 RYR1	1.88e-04	191	123	5	baa70781633a3fe5bf987f9d8dff3884f5167e7f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	USP13 STK32B ESRRG LRP1B LTBP2	1.88e-04	191	123	5	963f4f2e852bbb4faf070aafb0d368297abacd3b
ToppCell	(7)_Epithelial-E_(AT2)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCDC141 SULT1A2 TM7SF2 ROS1 SFN	1.88e-04	191	123	5	0fc8d109d5c50957ceef5b8b8b818b0c598b1bbe
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ESRRG MUC16 WDR49 RSPH9 HYDIN	1.88e-04	191	123	5	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	ESRRG MUC16 WDR49 RSPH9 HYDIN	1.88e-04	191	123	5	9d31c8424d35bdc0c27188b68bfd0f731af3600b
Computational	Neighborhood of CALM1	RALGAPA1 ASAP2 CLCN3 EIF4ENIF1 XPO6 MAP4K4	1.22e-04	110	76	6	GCM_CALM1
Disease	osteopetrosis (implicated_via_orthology)	LRRK1 CLCN3 CLCN4	2.21e-06	7	119	3	DOID:13533 (implicated_via_orthology)
Disease	Proteinuria	STK32B FAM151B LRP2	2.81e-05	15	119	3	HP_0000093
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR2	4.83e-05	3	119	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR2	4.83e-05	3	119	2	DOID:8545 (implicated_via_orthology)
Disease	Dent disease (implicated_via_orthology)	CLCN3 CLCN4	4.83e-05	3	119	2	DOID:0050699 (implicated_via_orthology)
Disease	Attention deficit hyperactivity disorder	CIC PTPRD MED13	1.22e-04	24	119	3	C1263846
Disease	hematocrit	RALGAPA1 PIEZO1 ESRRG DGKD ZC3H4 GYS2 PPP1R1B LRP2 MRPS6 TTC13 HYDIN RCN3 TP53BP1	2.27e-04	1011	119	13	EFO_0004348
Disease	Glioma	RAF1 CIC CLCN3 ROS1	4.32e-04	87	119	4	C0017638
Disease	cognitive function measurement, self reported educational attainment	ESRRG DPP8 EIF3CL EIF3C FBXO33 OGA NPAS2	6.09e-04	355	119	7	EFO_0004784, EFO_0008354
Disease	Kunitz-type protease inhibitor 2 measurement	RYR1 CATSPERG	7.11e-04	10	119	2	EFO_0008200
Disease	Sensory hearing loss	SLC26A4 LRP2	8.66e-04	11	119	2	C1691779
Disease	Primary Ciliary Dyskinesia	RPGRIP1L RSPH9 HYDIN	9.11e-04	47	119	3	C4551720
Disease	Myopia	SCN11A LRRC4C RYR2 PTPRD C3orf70 AKAP13 PNPLA8	9.78e-04	385	119	7	HP_0000545
Disease	lip morphology measurement	RPGRIP1L L1TD1 MAP4K4 KIF17 NPAS2	1.04e-03	189	119	5	EFO_0007845
Disease	Mental Retardation, X-Linked Nonsyndromic	HUWE1 CLCN4	1.22e-03	13	119	2	C3501611
Disease	neuroblastoma	MAPK1IP1L L1TD1 ASAP2 CEP295	1.27e-03	116	119	4	EFO_0000621
Disease	serum IgG glycosylation measurement	SLC9A9 CD207 LRRC4C RALGAPA2 LRP1B RYR2 SLC8A3 ASAP2	1.30e-03	523	119	8	EFO_0005193
Disease	Adenocarcinoma of lung (disorder)	IPO5 RAF1 RPS6KC1 ROS1 SFN	1.52e-03	206	119	5	C0152013
Disease	hemorheological measurement	STK32B PTPRD	1.64e-03	15	119	2	EFO_0803374
Disease	autosomal dominant intellectual developmental disorder (is_implicated_in)	RFX7 MED13	2.11e-03	17	119	2	DOID:0060307 (is_implicated_in)
Disease	smoking status measurement	STK32B ESRRG LRRC4C SLFN14 RYR2 PTPRD ZC3H4 INSC PPP1R1B CEP295 HERC1 UTRN	2.56e-03	1160	119	12	EFO_0006527
Disease	alkaline phosphatase measurement	RALGAPA1 SLC26A4 AXIN1 MRPL4 XPO6 AKAP13 PRR14L LTBP2 KIF17 UTRN TP53BP1	2.72e-03	1015	119	11	EFO_0004533
Disease	Malignant Glioma	RAF1 CLCN3 ROS1	2.88e-03	70	119	3	C0555198
Disease	mixed gliomas	RAF1 CLCN3 ROS1	2.88e-03	70	119	3	C0259783
Disease	exercise test	RYR2 PTPRD	2.92e-03	20	119	2	EFO_0004328
Disease	p-tau measurement	LRRC4C PTPRD PATJ	3.11e-03	72	119	3	EFO_0004763
Disease	gestational age, birth measurement	PTPRD INSC	3.22e-03	21	119	2	EFO_0005112, EFO_0006921
Disease	Obsessive-compulsive trait	PTPRD NPAS2	3.22e-03	21	119	2	HP_0008770
Disease	Attention Deficit Disorder	CIC PTPRD	3.53e-03	22	119	2	C0041671
Disease	Minimal Brain Dysfunction	CIC PTPRD	3.53e-03	22	119	2	C1321905
Disease	Sensorineural Hearing Loss (disorder)	SLC26A4 LRP2	3.86e-03	23	119	2	C0018784

Protein segments in the cluster

Peptide	Gene	Start	Entry
FEQEPVDTVSSLFHM	CATSPERG	66	Q6ZRH7
VDTVSSLFHMLVDSP	CATSPERG	71	Q6ZRH7
SVPFEMTTSEHIQDE	BDP1	1961	A6H8Y1
HPTEAIFSEDRNTME	BBX	781	Q8WY36
EFMVLLDSVLPESAH	BPIFB1	301	Q8TDL5
TTFDEAMADLHTLSE	SFN	196	P31947
MPIHEFSENVDSLTS	AFTPH	66	Q6ULP2
HNMIDDSTDPILSTI	GYS2	446	P54840
SDLFHSPSDDMDSII	AKAP13	1441	Q12802
PFTVTDHTPMETVVD	CLCN4	701	P51793
RMSPEEVSAHDALIS	C3orf70	156	A6NLC5
SIEELPSMEEISHSV	CASP8AP2	1661	Q9UKL3
DVLMTFPDTTDDHTL	ANO8	66	Q9HCE9
SMATREELTAFLHPE	RCN3	181	Q96D15
MIEDAIRSHSESASP	RAF1	276	P04049
EPHSITEDVTISAVM	NUP107	126	P57740
PPAAHSLSEEMELEF	P3H1	126	Q32P28
MCIVDEPLEEFTSRH	NPAS2	241	Q99743
EAEDVPVSMVSTDHA	MUC16	3701	Q8WXI7
LEDTVDTEDMQPSTH	MUC16	8336	Q8WXI7
SVKTMIVHDDVESEP	MAP4K4	811	O95819
IVHDDVESEPAMTPS	MAP4K4	816	O95819
FDREAVITMSEDDHP	LRP1B	2306	Q9NZR2
MPDDSVDEFDETIHL	RPGRIP1L	586	Q68CZ1
EDPRMLFVAAVDHSS	RPS6KC1	771	Q96S38
SEHDLTPMDGETFSQ	LRRK1	1891	Q38SD2
MPDQISVSEFVAETH	ASAP2	1	O43150
DTSLTDMHVVDVELS	ASPDH	216	A6ND91
EDEVDTMSPTIHTEA	KIAA1109	3501	Q2LD37
EDSGITEESFHEMIP	HERC1	4636	Q15751
TEESFHEMIPLDSFV	HERC1	4641	Q15751
HAVMDIESLSVFTEP	FBXO33	526	Q7Z6M2
TEEPMDTTSAVIHSE	SYNCRIP	11	O60506
IASPADSSELLMEVH	CBFA2T2	216	O43439
DHVTVPLALMFEDVT	PLXNB3	596	Q9ULL4
STAHMIEADVLLPSD	FAM151B	51	Q6UXP7
VDDEITGDTPMESHL	LRRC4C	571	Q9HCJ2
FSLELSDHSETMVPV	LRP2	2076	P98164
SSEDHDFDPTAEMLV	MIER3	16	Q7Z3K6
FDAHEDLSDTEEMFP	PITPNM2	346	Q9BZ72
EGMLHLFESITEDTV	PPP1R21	316	Q6ZMI0
PDSDVLSEIMHSFAK	IPO5	761	O00410
EVIFHVSTRMPSDSD	RALGAPA2	1716	Q2PPJ7
SILLEHVAEMEDPST	HK3	346	P52790
LEQDELHTFTDTMLP	HUWE1	1431	Q7Z6Z7
FSISASLHKPEMETE	NUDT13	116	Q86X67
EHPTDFSTEIMNVTE	PRPF39	26	Q86UA1
EEAVLTTMDITHDGF	TM7SF2	241	O76062
LFAIHEKMLSSEDSP	GPRC6A	41	Q5T6X5
TLSDMFELDLPTVHS	EIF3C	806	Q99613
ETLSDMFELDLPTVH	EIF3CL	806	B5ME19
PLTMTDDLEHFVFVI	HYDIN	2626	Q4G0P3
HFVEVSMSEEFLALP	KLHL18	166	O94889
DMEVEEPVSSSLSLH	CCDC141	1231	Q6ZP82
VMDHVSDSFLETNVP	CTNNA1	386	P35221
DATSPIMEELITFHD	MT-CO2	11	P00403
MDSVELCLPESFSLH	ESRRG	1	P62508
HVVPAVSDMELSETE	AXIN1	751	O15169
NDESEVEIIHVTSPM	DPP8	306	Q6V1X1
SEKVMFQSTHILPDE	CCDC191	286	Q8NCU4
SSTEDLPDHDIHMDI	LTBP2	1571	Q14767
SQMLHPIFEEASDVI	ERP44	61	Q9BS26
CSLHPEMLSEEEATQ	DGKD	966	Q16760
HLSSFLESMEEIVTA	INSC	361	Q1MX18
DLSLTDPESFSEHMD	CEP295	1976	Q9C0D2
MVDEVTPFLTAQATH	RYR1	666	P21817
ELMVDHTEPFVTAEA	RYR2	676	Q92736
LMVTHFDLELVDPDT	CYP8B1	456	Q9UNU6
TSDDHEFDPSADMLV	MIER1	16	Q8N108
EMLSSDQRETVTEPH	PRR14L	991	Q5THK1
EFDDTTEHDMIISGL	PTPRD	776	P23468
HSIFTISIEMSAVDE	KIF17	211	Q9P2E2
MSDEFSLADALPEHS	MAPK1IP1L	1	Q8NDC0
SATDTEEVHIMLDGL	PNPLA8	686	Q9NP80
EIVLTDSPDTLIMHF	FREM3	761	P0C091
LFEFVTDPSITHENM	RIOK1	381	Q9BRS2
PHDTSTDLTEVMEQI	UTRN	3401	P46939
TDLTEVMEQIHSTFP	UTRN	3406	P46939
RFSTMPETETHERET	TRMT5	56	Q32P41
MELIETHRPSEVVFS	SLFN14	836	P0C7P3
DLDPSLDFMDSLEHD	RSPH9	206	Q9H1X1
PTAAVESMVEHLSRD	MRPS6	71	P82932
MTFTTHIEDVHSEPL	TMC3	841	Q7Z5M5
LTHEEMPQSIVEATS	MRPL4	221	Q9BYD3
MSATDPVTVLAIFHE	SLC9A9	211	Q8IVB4
MLSFHEEQEVLPETF	OGA	821	O60502
FTMAEIEHFVDPSEK	GARS1	346	P41250
TVLSHEEDAMSLFSP	MED13	736	Q9UHV7
TLSSPEVRFHMDSET	DIS3	631	Q9Y2L1
PILTDDVSLQVFMDH	SEC23A	741	Q15436
THALSEVEVESDSFM	APEH	706	P13798
PFMAEHLEETLSAVT	EIF4ENIF1	456	Q9NRA8
ILMDSPEDADLFHSE	PRKAB1	36	Q9Y478
FEPTVFTDVEDHMFI	ALDH1L1	786	O75891
SDHDDAFLSIMSPEI	CIC	146	Q96RK0
MTVEKEAPDAHFTVD	CD207	1	Q9UJ71
EEFTHTTLAADVMRP	CLCN3	646	P51790
VERTMLDFPQHVSSD	NLN	101	Q9BYT8
FESIPDMLELDHLTV	UGP2	446	Q16851
EAIRHFSTMLQEEPD	TTC13	161	Q8NBP0
VSEVRTLMAELESHP	ZNF671	151	Q8TAW3
PMSSKEIVTLVEDFH	ZNF174	111	Q15697
TSFMLSLSHQEKPEE	RALGAPA1	1626	Q6GYQ0
VVLSMAPDEHFLVSS	SLC26A4	151	O43511
RTETSLPETEVDHNM	PATJ	651	Q8NI35
PEETVDLMVEHTSFK	SULT1A2	216	P50226
VSDAETESIFMEPIH	STYXL2	41	Q5VZP5
TESIFMEPIHLSSAI	STYXL2	46	Q5VZP5
ALPDSIEDEHFQMTL	YY2	106	O15391
FQPHEDRISSLEMCE	WDR49	471	Q8IV35
TESHPVTVEMFNTPE	ROS1	1646	P08922
SVMTIPEHSDINDLE	RFX7	706	Q2KHR2
EENMESVPLHLSLTE	TP53BP1	681	Q12888
DDCMFSHDPLTEETR	ZC3H4	461	Q9UPT8
EEEVLPFIPSASEHM	XPOT	716	O43592
IDMFSEDEPHLTIQD	SCN11A	966	Q9UI33
EIHSVTPIDEILNMF	STK32B	226	Q9NY57
TEAHSEVTFDMEILG	GTF3C5	101	Q9Y5Q8
EKSEELVDHFLPMTE	PLIN5	156	Q00G26
EISHSIMFEELPCVD	PIEZO1	2461	Q92508
PAFIHQSDVTDEMLS	XPO6	826	Q96QU8
AMLFRLSEHSSPEEE	PPP1R1B	36	Q9UD71
DTVALLMSNEPDFVH	SLC27A6	106	Q9Y2P4
SHPEFEEDSDFVIEM	USP13	766	Q92995
EMSEDIDHNLTPTLD	ZMYM4	36	Q5VZL5
FIVDPAHETTAELMN	UGGT1	501	Q9NYU2
LSSTLHDAVEMEDDP	KIAA0586	1261	Q9BVV6
TREHMPTLEEFFEEA	THOC1	456	Q96FV9
SSEEVPDFMEVPHSV	UNQ6126/PRO20091	66	Q6UXV3
HEVEITSDGMETTFI	L1TD1	456	Q5T7N2
ATTEALSMAHEVDPE	MX2	271	P20592
SSMSEVHTDEPEDFI	SLC8A3	381	P57103