Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

RAD51C ERCC2 ABCF1 DDX12P KIF26A NAIP SAE1 PSMC6 NUBP1 ATP13A5 ATP13A2 SWSAP1 CCT6A ACSM4 STARD9 ATP11A KIF18B SLC27A5

1.05e-0661415218GO:0140657
GeneOntologyMolecularFunctionligase activity, forming carbon-sulfur bonds

SAE1 SUCLG2 DIP2A ACSM4 SLC27A5

1.44e-05411525GO:0016877
GeneOntologyMolecularFunctionATP hydrolysis activity

ERCC2 ABCF1 DDX12P KIF26A NAIP PSMC6 NUBP1 ATP13A5 ATP13A2 SWSAP1 CCT6A ATP11A KIF18B

3.38e-0544115213GO:0016887
GeneOntologyMolecularFunctionligase activity

ACACA SAE1 PFAS SUCLG2 DIP2A HARS2 ACSM4 SLC27A5

5.72e-051741528GO:0016874
GeneOntologyMolecularFunctioncalcium ion binding

SELE PLCZ1 FAT4 ADGRE2 RYR2 CAPN11 PITPNM1 EYS FAT2 FBN1 HMCN1 OTOF ADGRE3 PITPNM3 AGRN SYT13 NOTCH4

5.82e-0574915217GO:0005509
GeneOntologyMolecularFunctionchondroitin sulfate binding

ADGRE2 PTPRS AGRN

6.82e-05111523GO:0035374
GeneOntologyMolecularFunctionacid-thiol ligase activity

SUCLG2 DIP2A ACSM4 SLC27A5

8.65e-05311524GO:0016878
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

EEFSEC MTG1 ERCC2 ABCF1 DDX12P KIF26A NAIP PSMC6 NUBP1 ATP13A5 ATP13A2 TUFM GFM2 SWSAP1 CCT6A ATP11A KIF18B

8.84e-0577515217GO:0017111
GeneOntologyMolecularFunctionpyrophosphatase activity

EEFSEC MTG1 ERCC2 ABCF1 DDX12P KIF26A NAIP PSMC6 NUBP1 ATP13A5 ATP13A2 TUFM GFM2 SWSAP1 CCT6A ATP11A KIF18B

2.27e-0483915217GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

EEFSEC MTG1 ERCC2 ABCF1 DDX12P KIF26A NAIP PSMC6 NUBP1 ATP13A5 ATP13A2 TUFM GFM2 SWSAP1 CCT6A ATP11A KIF18B

2.31e-0484015217GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

EEFSEC MTG1 ERCC2 ABCF1 DDX12P KIF26A NAIP PSMC6 NUBP1 ATP13A5 ATP13A2 TUFM GFM2 SWSAP1 CCT6A ATP11A KIF18B

2.31e-0484015217GO:0016818
GeneOntologyMolecularFunctiontranslation elongation factor activity

EEFSEC TUFM GFM2

4.48e-04201523GO:0003746
GeneOntologyMolecularFunctionproteoglycan binding

APP PTPRF PTPRS AGRN

6.11e-04511524GO:0043394
GeneOntologyMolecularFunctionsemaphorin receptor binding

SEMA6D SEMA6A PLXNB1

6.85e-04231523GO:0030215
GeneOntologyMolecularFunctionsulfur compound binding

ACACA APP ADGRE2 RYR2 FBN1 PTPRF PTPRS HADHA AGRN

8.42e-043231529GO:1901681
GeneOntologyMolecularFunctionCoA-ligase activity

DIP2A ACSM4 SLC27A5

1.11e-03271523GO:0016405
GeneOntologyMolecularFunctionchemorepellent activity

SEMA6D SEMA6A FLRT2

1.37e-03291523GO:0045499
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

APP PTPRS AGRN

1.37e-03291523GO:0043395
GeneOntologyBiologicalProcesscell-cell adhesion via plasma-membrane adhesion molecules

SELE ROBO4 FAT4 CD177 TAOK2 FAT2 PTPRD PTPRF HMCN1 PTPRS SDK1

1.37e-0531314511GO:0098742
DomainEGF_3

SELE FAT4 ADAM20 ADGRE2 EYS FAT2 FBN1 HMCN1 ADGRE3 AGRN NOTCH4 PEAR1

4.13e-0723514912PS50026
DomainEGF_CA

FAT4 ADGRE2 EYS FAT2 FBN1 HMCN1 ADGRE3 AGRN NOTCH4

5.82e-071221499SM00179
DomainEGF-like_Ca-bd_dom

FAT4 ADGRE2 EYS FAT2 FBN1 HMCN1 ADGRE3 AGRN NOTCH4

6.68e-071241499IPR001881
DomainEGF-like_dom

SELE FAT4 ADAM20 ADGRE2 EYS FAT2 FBN1 HMCN1 ADGRE3 AGRN NOTCH4 PEAR1

7.65e-0724914912IPR000742
DomainEGF

SELE FAT4 ADGRE2 EYS FAT2 FBN1 HMCN1 ADGRE3 AGRN NOTCH4 PEAR1

2.98e-0623514911SM00181
DomainEGF_1

SELE FAT4 ADAM20 ADGRE2 EYS FAT2 FBN1 HMCN1 AGRN NOTCH4 PEAR1

6.50e-0625514911PS00022
DomainEGF-like_CS

SELE FAT4 ADAM20 ADGRE2 EYS FAT2 FBN1 HMCN1 AGRN NOTCH4 PEAR1

8.11e-0626114911IPR013032
DomainEGF_2

SELE FAT4 ADAM20 ADGRE2 EYS FAT2 FBN1 HMCN1 AGRN NOTCH4 PEAR1

9.36e-0626514911PS01186
DomainEGF_Ca-bd_CS

FAT4 ADGRE2 EYS FBN1 HMCN1 ADGRE3 NOTCH4

1.26e-05971497IPR018097
DomainEGF_CA

FAT4 ADGRE2 EYS FBN1 HMCN1 ADGRE3 NOTCH4

1.44e-05991497PS01187
DomainASX_HYDROXYL

FAT4 ADGRE2 EYS FBN1 HMCN1 ADGRE3 NOTCH4

1.54e-051001497PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

FAT4 ADGRE2 EYS FBN1 HMCN1 ADGRE3 NOTCH4

2.25e-051061497IPR000152
DomainEGF_CA

FAT4 ADGRE2 FBN1 HMCN1 ADGRE3 NOTCH4

6.48e-05861496PF07645
DomainIGc2

ROBO4 FCRL6 PTPRD PTPRF HMCN1 PTPRS LSAMP KIT SDK1

1.15e-042351499SM00408
DomainIg_sub2

ROBO4 FCRL6 PTPRD PTPRF HMCN1 PTPRS LSAMP KIT SDK1

1.15e-042351499IPR003598
DomainG_TR_1

EEFSEC TUFM GFM2

1.34e-04131493PS00301
Domain-

ATP13A5 ATP13A2 PITPNM1 PITPNM3 ATP11A

1.58e-046414953.40.50.1000
DomainLAM_G_DOMAIN

FAT4 EYS FAT2 AGRN

2.33e-04381494PS50025
DomainGrowth_fac_rcpt_

FAT4 ADGRE2 EYS FBN1 HMCN1 ADGRE3 NOTCH4

2.58e-041561497IPR009030
DomainEFTu-like_2

EEFSEC TUFM GFM2

3.72e-04181493IPR004161
DomainGTP_EFTU_D2

EEFSEC TUFM GFM2

3.72e-04181493PF03144
DomainG_TR_2

EEFSEC TUFM GFM2

3.72e-04181493PS51722
DomainP5-ATPase

ATP13A5 ATP13A2

3.75e-0441492PF12409
DomainLamG

FAT4 EYS FAT2 AGRN

4.12e-04441494SM00282
DomainHAD-like_dom

ATP13A5 ATP13A2 PITPNM1 PITPNM3 ATP11A

4.24e-04791495IPR023214
DomainTF_GTP-bd_dom

EEFSEC TUFM GFM2

4.39e-04191493IPR000795
DomainEGF

SELE EYS FAT2 HMCN1 AGRN NOTCH4

5.23e-041261496PF00008
Domain-

ACACA ECHDC3 HADHA

5.96e-042114933.90.226.10
DomainClpP/crotonase-like_dom

ACACA ECHDC3 HADHA

5.96e-04211493IPR029045
DomainNUT

NUTM2A NUTM2B

6.22e-0451492IPR024310
DomainNUT_N

NUTM2A NUTM2B

6.22e-0451492IPR024309
DomainNUT

NUTM2A NUTM2B

6.22e-0451492PF12881
DomainP-type_TPase_V

ATP13A5 ATP13A2

6.22e-0451492IPR006544
DomainIg_I-set

ROBO4 PTPRD PTPRF HMCN1 PTPRS LSAMP SDK1

8.40e-041901497IPR013098
DomainI-set

ROBO4 PTPRD PTPRF HMCN1 PTPRS LSAMP SDK1

8.40e-041901497PF07679
DomainLNS2

PITPNM1 PITPNM3

9.29e-0461492IPR013209
DomainPI_transfer

PITPNM1 PITPNM3

9.29e-0461492IPR001666
DomainLNS2

PITPNM1 PITPNM3

9.29e-0461492SM00775
DomainDDHD

PITPNM1 PITPNM3

9.29e-0461492PF02862
DomainDDHD

PITPNM1 PITPNM3

9.29e-0461492PS51043
DomainDDHD_dom

PITPNM1 PITPNM3

9.29e-0461492IPR004177
DomainLNS2

PITPNM1 PITPNM3

9.29e-0461492PF08235
DomainLNS2/PITP

PITPNM1 PITPNM3

9.29e-0461492IPR031315
DomainDDHD

PITPNM1 PITPNM3

9.29e-0461492SM01127
DomainLaminin_G

FAT4 EYS FAT2 AGRN

1.18e-03581494IPR001791
DomainTransl_B-barrel

EEFSEC TUFM GFM2

1.26e-03271493IPR009000
DomainhEGF

FAT4 EYS NOTCH4

1.41e-03281493PF12661
DomainIg-like_fold

ROBO4 ICAM3 CAMTA2 FCRL6 PTPRD PTPRF HMCN1 PTPRS PKHD1 LSAMP FLRT2 KIT SDK1 PLXNB1

1.57e-0370614914IPR013783
DomainAMP-binding

DIP2A ACSM4 SLC27A5

1.73e-03301493PF00501
DomainAMP-dep_Synth/Lig

DIP2A ACSM4 SLC27A5

1.73e-03301493IPR000873
DomainSemap_dom

SEMA6D SEMA6A PLXNB1

1.90e-03311493IPR001627
DomainSEMA

SEMA6D SEMA6A PLXNB1

1.90e-03311493PS51004
DomainTIG

CAMTA2 PKHD1 PLXNB1

1.90e-03311493PF01833
DomainSema

SEMA6D SEMA6A PLXNB1

1.90e-03311493SM00630
DomainSema

SEMA6D SEMA6A PLXNB1

1.90e-03311493PF01403
Domainfn3

ROBO4 PTPRD PTPRF PTPRS FLRT2 SDK1

1.92e-031621496PF00041
DomainIG

ROBO4 ICAM3 FCRL6 PTPRD PTPRF HMCN1 PTPRS LSAMP KIT SDK1

2.06e-0342114910SM00409
DomainIg_sub

ROBO4 ICAM3 FCRL6 PTPRD PTPRF HMCN1 PTPRS LSAMP KIT SDK1

2.06e-0342114910IPR003599
DomainIPT

CAMTA2 PKHD1 PLXNB1

2.08e-03321493IPR002909
Domain-

ATP13A5 ATP13A2 ATP11A

2.08e-033214933.40.1110.10
DomainPlexin_repeat

SEMA6D SEMA6A PLXNB1

2.08e-03321493IPR002165
Domain-

ATP13A5 ATP13A2 ATP11A

2.08e-033214932.70.150.10
DomainPSI

SEMA6D SEMA6A PLXNB1

2.08e-03321493PF01437
DomainG_TR_CS

TUFM GFM2

2.19e-0391492IPR031157
Domain-

ROBO4 ICAM3 FCRL6 PTPRD PTPRF HMCN1 PTPRS PKHD1 LSAMP FLRT2 KIT SDK1 PLXNB1

2.55e-03663149132.60.40.10
DomainATPase_P-typ_cyto_domN

ATP13A5 ATP13A2 ATP11A

2.70e-03351493IPR023299
DomainENOYL_COA_HYDRATASE

ECHDC3 HADHA

2.73e-03101492PS00166
DomainATPase_P-typ_P_site

ATP13A5 ATP13A2 ATP11A

2.93e-03361493IPR018303
DomainPTPc

PTPRD PTPRF PTPRS

2.93e-03361493SM00194
DomainP_typ_ATPase

ATP13A5 ATP13A2 ATP11A

2.93e-03361493IPR001757
DomainATPASE_E1_E2

ATP13A5 ATP13A2 ATP11A

2.93e-03361493PS00154
Pubmed

C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.

MYC RAD51C DNAJB11 ERCC2 DDX12P AIMP2 ACACA PDHB SAE1 SPART PSMC6 PFAS OAT PFKP TUFM STT3A CSDE1 CCT6A SF3B3 TRIM32 FIP1L1 ELP2 HADHA USP1 TBCD LRRC41

5.91e-1112571542637317656
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

EEFSEC RC3H2 ABCF1 ANGEL1 PFAS TUFM CSDE1 DIP2A TRIM32 ARHGEF7 TONSL YY1AP1 ELP2 AGRN PLXNB1 LRRC41

3.64e-086501541638777146
Pubmed

LAR receptor phospho-tyrosine phosphatases regulate NMDA-receptor responses.

PTPRD PTPRF PTPRS

8.51e-083154331985401
Pubmed

Trans-synaptic adhesions between netrin-G ligand-3 (NGL-3) and receptor tyrosine phosphatases LAR, protein-tyrosine phosphatase delta (PTPdelta), and PTPsigma via specific domains regulate excitatory synapse formation.

PTPRD PTPRF PTPRS

8.51e-083154320139422
Pubmed

Intact synapse structure and function after combined knockout of PTPδ, PTPσ, and LAR.

PTPRD PTPRF PTPRS

8.51e-083154333656439
Pubmed

Amyloid β production is regulated by β2-adrenergic signaling-mediated post-translational modifications of the ryanodine receptor.

APP RYR2 ADRB2

8.51e-083154328476886
Pubmed

Developmental expression of the cell adhesion molecule-like protein tyrosine phosphatases LAR, RPTPdelta and RPTPsigma in the mouse.

PTPRD PTPRF PTPRS

8.51e-08315439784606
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ERCC2 IMPDH1 ACACA KIF26A THAP8 IPP PFAS CFAP43 ATP13A2 TAOK2 DIP2A HAUS4 PTPRF PTPRS COQ4 NEK8 ARHGAP44 PRDM16 AGRN TBCD

1.05e-0711051542035748872
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

DNAJB11 ACACA SAE1 SPART PSMC6 PFAS OAT PFKP SUCLG2 CSDE1 BPNT1 XPNPEP3 HADHA PYCR3

1.26e-075341541435032548
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

MYC DNAJB11 ABCF1 AIMP2 ACACA PDHB SAE1 PSMC6 PFAS PFKP SUCLG2 TUFM CSDE1 CCT6A SF3B3 TRIM32 MIB1 FIP1L1 HADHA KIF18B AGRN PYCR3

1.47e-0713531542229467282
Pubmed

USP11 mediates repair of DNA-protein cross-links by deubiquitinating SPRTN metalloprotease.

DNAJB11 ACACA PDHB SAE1 PSMC6 OAT PFKP SUCLG2 TUFM STT3A CCT6A HADHA KIF18B PYCR3

2.50e-075651541433567341
Pubmed

The LAR/PTP delta/PTP sigma subfamily of transmembrane protein-tyrosine-phosphatases: multiple human LAR, PTP delta, and PTP sigma isoforms are expressed in a tissue-specific manner and associate with the LAR-interacting protein LIP.1.

PTPRD PTPRF PTPRS

3.39e-07415438524829
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

AIMP2 ACACA ATG13 HDAC8 NAIP APP STT3A CSDE1 KIDINS220 PTPRS EEPD1 ARHGAP44 XPNPEP3 CNDP2 TMPRSS2 ATP11A SEMA6A PNPLA7 LSM7 TBCD LRRC41 SOS2

7.39e-0714891542228611215
Pubmed

Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPs.

PTPRD PTPRF PTPRS

8.46e-075154310777529
Pubmed

Interleukin-1 receptor accessory protein organizes neuronal synaptogenesis as a cell adhesion molecule.

PTPRD PTPRF PTPRS

8.46e-075154322357843
Pubmed

Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.

ROBO4 ABCF1 AIMP2 ACACA SPART ZC3HC1 TUFM STT3A CSDE1 CCT6A SF3B3 FIP1L1 ELP2 HADHA

1.39e-066531541433742100
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

ERCC2 ABCF1 AIMP2 ACACA PDHB SAE1 PSMC6 OAT SUCLG2 TUFM ADD1 STT3A CSDE1 CCT6A SF3B3 MIB1 CNDP2 HADHA AGRN PYCR3

1.65e-0613181542030463901
Pubmed

Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases.

PTPRD PTPRF PTPRS

1.69e-066154319273906
Pubmed

Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.

RAD51C MTG1 DNAJB11 PDPR ACACA PDHB OAT PFKP TUFM GFM2 STT3A ECHDC3 HAUS4 FBN1 SF3B3 XPNPEP3 FIP1L1 HADHA PNPLA7 AGRN PYCR3

1.88e-0614511542130550785
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

DNAJB11 ABCF1 PDPR PDHB SPART PFAS OAT PFKP APP ADD1 STT3A DIP2A SF3B3 KIDINS220 MIB1 CNDP2 ELP2 SEMA6A HADHA PYCR3 LRRC41

2.75e-0614871542133957083
Pubmed

Intra- and intermolecular interactions between intracellular domains of receptor protein-tyrosine phosphatases.

PTPRD PTPRF PTPRS

2.94e-067154312376545
Pubmed

Modulation of apoptotic response by LAR family phosphatases-cIAP1 signaling during urinary tract morphogenesis.

PTPRD PTPRF PTPRS

2.94e-067154329073098
Pubmed

KAP1 facilitates reinstatement of heterochromatin after DNA replication.

ERCC2 ABCF1 PDPR ACACA PDHB SAE1 PSMC6 PFAS PFKP SUCLG2 TUFM CCT6A ELP2 HADHA

3.32e-067041541429955894
Pubmed

Interaction of amyotrophic lateral sclerosis/frontotemporal lobar degeneration-associated fused-in-sarcoma with proteins involved in metabolic and protein degradation pathways.

ACACA SAE1 OAT TUFM CCT6A HARS2 SF3B3 PYCR3

3.43e-06201154825192599
Pubmed

An extracellular biochemical screen reveals that FLRTs and Unc5s mediate neuronal subtype recognition in the retina.

SEMA6D SEMA6A FLRT2 SDK1 PLXNB1

3.50e-0652154526633812
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

DNAJB11 ABCF1 AIMP2 ACACA PDHB SAE1 SPART PSMC6 PFAS PFKP TUFM ADD1 CCT6A SF3B3 XPNPEP3 FIP1L1 HADHA PYCR3

3.68e-0611491541835446349
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

SPAG1 PDHB ANGEL1 SPART PSMC6 STT3A CSDE1 ARHGEF7 ATP11A MFSD8 AGRN SYT13 TBCD CHST3

4.22e-067191541435337019
Pubmed

Combinatorial expression of neurexins and LAR-type phosphotyrosine phosphatase receptors instructs assembly of a cerebellar circuit.

PTPRD PTPRF PTPRS

4.69e-068154337591863
Pubmed

Protein Tyrosine Phosphatase δ Mediates the Sema3A-Induced Cortical Basal Dendritic Arborization through the Activation of Fyn Tyrosine Kinase.

PTPRD PTPRF PTPRS

4.69e-068154328637841
Pubmed

Direct interaction between the PRDM3 and PRDM16 tumor suppressors and the NuRD chromatin remodeling complex.

PDHB PSMC6 PFKP SUCLG2 TUFM CCT6A HADHA PRDM16

5.64e-06215154830462309
Pubmed

Mitochondrial Raf1 Regulates Glutamine Catabolism.

SPAG1 PDHB ZNF618 APP SUCLG2 TUFM BPNT1 FBP1 HADHA

6.00e-06288154938496616
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

DNAJB11 ABCF1 PDHB ZNF618 TUFM STT3A CCT6A SF3B3 KIDINS220 TRIM32 ARHGEF7 XPNPEP3 FIP1L1 HADHA LSM7 AGRN PLXNB1

6.72e-0610821541738697112
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

SPAG1 ABCF1 PDPR ACACA PDHB SPART PSMC6 PFAS PFKP SUCLG2 TUFM STT3A CSDE1 CCT6A BPNT1 SF3B3 TRIM32 HADHA TBCD

1.07e-0513671541932687490
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

ABCF1 AIMP2 IMPDH1 ACACA PDHB SAE1 PSMC6 PFAS OAT PFKP APP TUFM ADD1 CCT6A SF3B3 CNDP2 FIP1L1 HADHA

1.12e-0512471541827684187
Pubmed

PTPσ functions as a presynaptic receptor for the glypican-4/LRRTM4 complex and is essential for excitatory synaptic transmission.

PTPRD PTPRF PTPRS

1.37e-0511154325624497
Pubmed

A novel receptor-type protein tyrosine phosphatase with a single catalytic domain is specifically expressed in mouse brain.

PTPRD PTPRF PTPRS

1.37e-051115437832766
Pubmed

Transcription and Signaling Regulators in Developing Neuronal Subtypes of Mouse and Human Enteric Nervous System.

MYC SATB2 PTPRD SEMA6D PTPRS SEMA6A FLRT2 PLXNB1

1.73e-05251154829031500
Pubmed

SARS-CoV-2 uses Spike glycoprotein to control the host's anaerobic metabolism by inhibiting LDHB.

DNAJB11 AIMP2 PDHB PFAS OAT PFKP SUCLG2 CSDE1 BPNT1 SF3B3 HADHA TBCD

1.81e-056071541239147351
Pubmed

Novel association strategy with copy number variation for identifying new risk Loci of human diseases.

PDPR NRAP PTPRD

1.82e-0512154320808825
Pubmed

hSWS1·SWSAP1 is an evolutionarily conserved complex required for efficient homologous recombination repair.

RAD51C TUFM SWSAP1

1.82e-0512154321965664
Pubmed

Liprins, a family of LAR transmembrane protein-tyrosine phosphatase-interacting proteins.

PTPRD PTPRF PTPRS

1.82e-051215439624153
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

EEFSEC DNAJB11 ABCF1 AIMP2 PDHB PSMC6 OAT TUFM GFM2 ADD1 STT3A FIP1L1 PYCR3

1.83e-057111541333022573
Pubmed

Blocking beta2-adrenergic receptor attenuates acute stress-induced amyloid beta peptides production.

APP ADRB2

1.95e-052154220059989
Pubmed

The neuronal protein Kidins220/ARMS associates with ICAM-3 and other uropod components and regulates T-cell motility.

ICAM3 KIDINS220

1.95e-052154221381019
Pubmed

Early induction of c-Myc is associated with neuronal cell death.

MYC APP

1.95e-052154222005580
Pubmed

Ubiquitin-specific protease 1 acts as an oncogene and promotes lenvatinib efficacy in hepatocellular carcinoma by stabilizing c-kit.

USP1 KIT

1.95e-052154235045360
Pubmed

The mouse gene Ptprf encoding the leukocyte common antigen-related molecule LAR: cloning, characterization, and chromosomal localization.

PTPRD PTPRF

1.95e-05215427665159
Pubmed

The role of mast cells in the development of skin fibrosis in tight-skin mutant mice.

FBN1 KIT

1.95e-05215427704626
Pubmed

Rho-kinase inhibitor hydroxyfasudil protects against HIV-1 Tat-induced dysfunction of tight junction and neprilysin/Aβ transfer receptor expression in mouse brain microvessels.

APP MMEL1

1.95e-052154233548010
Pubmed

A positive feedback loop between PFKP and c-Myc drives head and neck squamous cell carcinoma progression.

MYC PFKP

1.95e-052154238982480
Pubmed

Intranasal phosphoramidon increases beta-amyloid levels in wild-type and NEP/NEP2-deficient mice.

APP MMEL1

1.95e-052154220941644
Pubmed

Limiting RyR2 Open Time Prevents Alzheimer's Disease-Related Neuronal Hyperactivity and Memory Loss but Not β-Amyloid Accumulation.

APP RYR2

1.95e-052154232966798
Pubmed

NEK8 regulates colorectal cancer progression via phosphorylating MYC.

MYC NEK8

1.95e-052154237596667
Pubmed

Mast cells are required for angiogenesis and macroscopic expansion of Myc-induced pancreatic islet tumors.

MYC KIT

1.95e-052154217906636
Pubmed

The second catalytic domain of protein tyrosine phosphatase delta (PTP delta) binds to and inhibits the first catalytic domain of PTP sigma.

PTPRD PTPRS

1.95e-05215429566880
Pubmed

Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

ROBO4 ICAM3 APP FAT2 PTPRF PTPRS KIT PLXNB1

2.05e-05257154816335952
Pubmed

Evolutionarily conserved regulators of tau identify targets for new therapies.

DNAJB11 PSMC6 PFKP APP STT3A CCT6A PTPRF TRIM32 PTPRS HADHA PYCR3

2.06e-055161541136610398
Pubmed

Alternative splice variants encoding unstable protein domains exist in the human brain.

FAT2 PTPRF ARHGEF7

2.36e-0513154315491607
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

DNAJB11 ABCF1 AIMP2 IMPDH1 ACACA PDHB SAE1 PSMC6 ZC3HC1 NUBP1 PFAS PFKP TUFM CSDE1 CCT6A CNDP2 ELP2 PYCR3 TBCD

2.53e-0514551541922863883
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SATB2 PDPR KIF26A SPART TAOK2 SF3B3 ARHGEF7 MIB1 NDRG4 SYT13 PLXNB1

2.58e-055291541114621295
Pubmed

Interactome of the Autoimmune Risk Protein ANKRD55.

ACACA PDHB OAT TUFM SF3B3 MIB1 PYCR3

2.96e-05197154731620119
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

DNAJB11 TRAF3 PDHB SAE1 PSMC6 PFAS OAT PFKP STT3A KIDINS220 PTPRD PTPRF TRIM32 PTPRS PYCR3

3.03e-059741541528675297
Pubmed

MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.

MYC RC3H2 SATB2 APP CSDE1 SEMA6D MIB1 SEMA6A SDK1

3.35e-05358154932460013
Pubmed

Gene co-regulation by Fezf2 selects neurotransmitter identity and connectivity of corticospinal neurons.

SATB2 KIF26A SLC15A2 FLRT2

3.63e-0542154424997765
Pubmed

IKAP localizes to membrane ruffles with filamin A and regulates actin cytoskeleton organization and cell migration.

DNAJB11 ACACA ELP2

3.73e-0515154318303054
Pubmed

SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.

PDHB NUTM2A SAE1 SPART ZC3HC1 OAT SUCLG2 STT3A CCT6A NUTM2B CNDP2 HADHA PYCR3 TBCD

3.88e-058781541437223481
Pubmed

Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.

SPAG1 PFAS PFKP GFM2 STT3A TRIM32 CNDP2 PNPLA7

3.97e-05282154835007762
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

DNAJB11 ABCF1 ACACA PDHB OAT APP RYR2 TAOK2 PITPNM1 CSDE1 CCT6A ARHGEF7 PITPNM3 CNDP2 HADHA NDRG4

4.90e-0511391541636417873
Pubmed

A dual-strategy expression screen for candidate connectivity labels in the developing thalamus.

SEMA6D SEMA6A KIT SDK1 PLXNB1

5.46e-0591154528558017
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPRD PTPRF PTPRS

5.53e-0517154319727691
Pubmed

ARHGAP44-mediated regulation of the p53/C-myc/Cyclin D1 pathway in modulating the malignant biological behavior of osteosarcoma cells.

MYC ARHGAP44

5.83e-053154238031136
Pubmed

Loss of non-motor kinesin KIF26A causes congenital brain malformations via dysregulated neuronal migration and axonal growth as well as apoptosis.

SATB2 KIF26A

5.83e-053154236228617
Pubmed

Binding of amyloid beta peptide to beta2 adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity.

APP ADRB2

5.83e-053154220395454
Pubmed

Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D.

SEMA6D SEMA6A

5.83e-053154228453731
Pubmed

β2-adrenergic receptor signaling promotes pancreatic ductal adenocarcinoma (PDAC) progression through facilitating PCBP2-dependent c-myc expression.

MYC ADRB2

5.83e-053154226803058
Pubmed

Pitpnm1 is expressed in hair cells during development but is not required for hearing.

PITPNM1 PITPNM3

5.83e-053154223820044
Pubmed

The cerebellum modulates thirst.

FBN1 PTPRD

5.83e-053154238987435
Pubmed

TRAF3 regulates the oncogenic proteins Pim2 and c-Myc to restrain survival in normal and malignant B cells.

MYC TRAF3

5.83e-053154231501481
Pubmed

The A3243G tRNALeu(UUR) MELAS mutation causes amino acid misincorporation and a combined respiratory chain assembly defect partially suppressed by overexpression of EFTu and EFG2.

TUFM GFM2

5.83e-053154218753147
Pubmed

The FIP1L1-PDGFRA fusion gene and the KIT D816V mutation are coexisting in a small subset of myeloid/lymphoid neoplasms with eosinophilia.

FIP1L1 KIT

5.83e-053154224458279
Pubmed

SATB1 and SATB2 play opposing roles in c-Myc expression and progression of colorectal cancer.

MYC SATB2

5.83e-053154226701851
Pubmed

alpha-Tocopherol transfer protein inhibition is effective in the prevention of cerebral malaria in mice.

SEC14L6 SEC14L4

5.83e-053154219923370
Pubmed

Neprilysin-2 is an important β-amyloid degrading enzyme.

APP MMEL1

5.83e-053154221224067
Pubmed

Amyloid beta induces cellular relocalization and production of agrin and glypican-1.

APP AGRN

5.83e-053154219166823
Pubmed

The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.

NUTM2E NUTM2B

5.83e-053154226542179
Pubmed

SUCLG2 identified as both a determinator of CSF Aβ1-42 levels and an attenuator of cognitive decline in Alzheimer's disease.

APP SUCLG2

5.83e-053154225027320
Pubmed

The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.

NUTM2A NUTM2B

5.83e-053154222456610
Pubmed

c-Myc-IMPDH1/2 axis promotes tumourigenesis by regulating GTP metabolic reprogramming.

MYC IMPDH1

5.83e-053154236629054
Pubmed

Chondroitin Sulfate Proteoglycans Negatively Modulate Spinal Cord Neural Precursor Cells by Signaling Through LAR and RPTPσ and Modulation of the Rho/ROCK Pathway.

PTPRD PTPRF

5.83e-053154225703008
Pubmed

Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer's disease.

APP KIT

5.83e-053154234609281
Pubmed

Structural basis for LAR-RPTP/Slitrk complex-mediated synaptic adhesion.

PTPRD PTPRS

5.83e-053154225394468
Pubmed

Key roles for MYC, KIT and RET signaling in secondary angiosarcomas.

MYC KIT

5.83e-053154224983371
Pubmed

Akt-dependent expression of NAIP-1 protects neurons against amyloid-{beta} toxicity.

NAIP APP

5.83e-053154215797869
Pubmed

Chromosomal localization, genomic organization and evolution of the genes encoding human phosphatidylinositol transfer protein membrane-associated (PITPNM) 1, 2 and 3.

PITPNM1 PITPNM3

5.83e-053154215627748
Pubmed

Tripartite containing motif 32 modulates proliferation of human neural precursor cells in HIV-1 neurodegeneration.

MYC TRIM32

5.83e-053154226586575
Pubmed

Hypertension genes and retinal vascular calibre: the Cardiovascular Health Study.

ADD1 ADRB2

5.83e-053154219148102
Pubmed

CCT6A promotes esophageal squamous cell carcinoma cell proliferation, invasion and epithelial-mesenchymal transition by activating TGF-β/Smad/c-Myc pathway.

MYC CCT6A

5.83e-053154237017854
Pubmed

Activation of β2-adrenergic Receptor Ameliorates Amyloid-β-induced Mitophagy Defects and Tau Pathology in Mice.

APP ADRB2

5.83e-053154236208707
Pubmed

Stem cell-related proteins C-KIT, C-MYC and BMI-1 in juvenile nasopharyngeal angiofibroma--do they have a role?

MYC KIT

5.83e-053154221113618
Pubmed

EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.

PDHB SAE1 PSMC6 OAT PFKP SUCLG2 TUFM CCT6A SF3B3 CNDP2 HADHA AGRN SOS2

6.36e-058031541336517590
InteractionC9orf72 interactions

MYC RAD51C DNAJB11 ERCC2 DDX12P AIMP2 ACACA PDHB ATG13 SAE1 SPART PSMC6 PFAS OAT PFKP APP TUFM STT3A CSDE1 CCT6A SF3B3 TRIM32 FIP1L1 ELP2 HADHA USP1 TBCD LRRC41

3.69e-07131914928int:C9orf72
InteractionTOP3B interactions

RC3H2 ERCC2 IMPDH1 ACACA KIF26A THAP8 IPP PFAS CFAP43 PFKP APP ATP13A2 TUFM TAOK2 CSDE1 DIP2A HAUS4 PTPRF PTPRS COQ4 NEK8 ARHGAP44 MIB1 HADHA PRDM16 AGRN TBCD

9.41e-06147014927int:TOP3B
InteractionBCAT2 interactions

MYC IMPDH1 APP PTPRF USP1

1.25e-05411495int:BCAT2
InteractionECH1 interactions

MYC DNAJB11 TRAF3 ACACA APP SUCLG2 COQ4 XPNPEP3 MIB1 HADHA

1.93e-0525314910int:ECH1
InteractionEGLN3 interactions

DNAJB11 PDPR ACACA PDHB ANGEL1 SAE1 PSMC6 NUBP1 PFAS SUCLG2 TUFM STT3A TAOK2 CCT6A HAUS4 KIDINS220 ADRB2 TONSL MIB1 ELP2 HADHA LSM7 PYCR3 LRRC41

2.78e-05129614924int:EGLN3
GeneFamilyBlood group antigens|CD molecules|I-set domain containing|Immunoglobulin like domain containing

ROBO4 PTPRD PTPRF HMCN1 PTPRS LSAMP SDK1

2.92e-05161997593
GeneFamilyProtein tyrosine phosphatases, receptor type

PTPRD PTPRF PTPRS

1.97e-0421993813
GeneFamilyFibronectin type III domain containing

ROBO4 PTPRD PTPRF PTPRS FLRT2 SDK1

2.49e-04160996555
GeneFamilyCD molecules|Adhesion G protein-coupled receptors, subfamily E

ADGRE2 ADGRE3

2.94e-045992915
GeneFamilyParkinson disease associated genes|ATPase orphan transporters

ATP13A5 ATP13A2

2.94e-0459921213
GeneFamilySEC14 family|PRELI domain containing

SEC14L6 SEC14L4

4.39e-0469921063
GeneFamilyPhosphatidylinositol transfer proteins

PITPNM1 PITPNM3

4.39e-0469921151
GeneFamilyKinesins|Pleckstrin homology domain containing

KIF26A STARD9 KIF18B

2.04e-0346993622
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

TRAF3 ZC3HC1

2.98e-031599226
GeneFamilyCadherin related

FAT4 FAT2

3.83e-031799224
GeneFamilyImmunoglobulin like domain containing|Semaphorins

SEMA6D SEMA6A

5.29e-0320992736
ToppCellPND01-03-samps-Endothelial-Postnatal_endothelial-endothelial_cells_D|PND01-03-samps / Age Group, Lineage, Cell class and subclass

ROBO4 TRAF3 KIF26A ADGRE2 SEMA6D SEMA6A KIT AGRN NOTCH4

1.09e-081741559b4f3f5334803e5903bc496decf923f2e44f7fa3c
ToppCell356C-Endothelial_cells-Endothelial-E-|356C / Donor, Lineage, Cell class and subclass (all cells)

KIF26A APP CAPN11 ARHGAP29 SEMA6A KIT NDRG4 NOTCH4 PEAR1

1.94e-0818615592e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell356C-Endothelial_cells-Endothelial-E|356C / Donor, Lineage, Cell class and subclass (all cells)

KIF26A APP CAPN11 ARHGAP29 SEMA6A KIT NDRG4 NOTCH4 PEAR1

1.94e-081861559c3449e54454009973818fc1101933c6f0168258c
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROBO4 FAT4 APP STARD9 EEPD1 ARHGAP29 SEMA6A NDRG4 NOTCH4

2.33e-0819015590e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROBO4 FAT4 APP STARD9 EEPD1 ARHGAP29 SEMA6A NDRG4 NOTCH4

2.44e-081911559f229abf69a1217194f74b0502486907e07dba989
ToppCellfacs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

APP ADGRE2 ADRB2 SLC24A4 HMCN1 ARHGAP29 SEMA6A KIT NOTCH4

2.56e-0819215594bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

FAT4 EMILIN1 RYR2 FBN1 PTPRD HMCN1 PTPRS LSAMP SDK1

2.67e-081931559acad568621ed677031797b8c2e34dafea798d681
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lung|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO4 APP ADGRE2 ATP13A2 HMCN1 ARHGAP29 SEMA6A KIT NOTCH4

2.79e-081941559f159ef8541d75a4e98468947f231bb463bec922c
ToppCell10x5'v1-week_17-19-Endothelial|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 FAT4 THSD7B BOK HMCN1 ARHGAP29 SEMA6A FLRT2

2.79e-081941559e141beafc9252e5d8c949252bfab53e127c881dc
ToppCell10x5'v1-week_17-19-Endothelial-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 FAT4 THSD7B BOK HMCN1 ARHGAP29 SEMA6A FLRT2

2.79e-081941559953578102ffc7b612ee8fce45e414750800fef5d
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MUC19 ATP13A5 RYR2 HMCN1 PKHD1 SYT13 UNC80 CHST3

1.89e-071751558887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SELE ROBO4 KLK10 KIF26A FBN1 HMCN1 ARHGAP29 TBCD

2.55e-071821558d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RYR2 MELTF PTPRD HMCN1 PKHD1 SDK1 UNC80

2.77e-0718415582cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RYR2 MELTF PTPRD HMCN1 PKHD1 SDK1 UNC80

2.77e-071841558ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAT4 RYR2 MELTF PTPRD HMCN1 PKHD1 SDK1 UNC80

2.77e-0718415582b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PFKP SEMA6D HMCN1 EEPD1 ARHGAP44 PKHD1 ARHGAP29 PRDM16

3.13e-071871558f124d2c699b717b7c02a1a70493f515b83dc2f4c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PFKP SEMA6D HMCN1 EEPD1 ARHGAP44 PKHD1 ARHGAP29 PRDM16

3.39e-071891558e32172ad09e93f6ac6ea2b92145b2b73003f7970
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ADGRE2 EMILIN1 RYR2 FBN1 PTPRD PTPRS LSAMP SDK1

3.39e-0718915582a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellCOVID-19-kidney-VWF+PLVAP+EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

ROBO4 APP ARHGEF7 ARHGAP29 SEMA6A KIT NOTCH4 TBCD

3.68e-0719115582f00d0b7b2ffce8eb3eb5bbae49a0d425b23c982
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ROBO4 FAT4 KIF26A HMCN1 ARHGAP29 SEMA6A FLRT2 AGRN

3.68e-071911558dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCellLPS-antiTNF-Endothelial-Endothelial-Activated_Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SELE ROBO4 KIF26A ANGEL1 HMCN1 SEMA6A KIT NOTCH4

3.83e-0719215580aeb5351275c0a91151ea2d52b2cdde172da6731
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO4 FAT4 APP EMILIN1 SEMA6D SEMA6A KIT PEAR1

4.14e-071941558c8b9551b93a5aed62154b487db90130604a6125c
ToppCell10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 THSD7B BOK HMCN1 ARHGAP29 SEMA6A FLRT2

4.30e-07195155822a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCell10x3'2.3-week_14-16-Endothelial-stroma-sinusoidal_EC|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 APP ARHGAP29 SEMA6A FLRT2 NDRG4 NOTCH4

4.65e-071971558f1080d93acf1a4756d2f2c8cabd1fb50bc7bcd09
ToppCell10x3'2.3-week_17-19-Endothelial-stroma-sinusoidal_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 SEMA6D HMCN1 ARHGAP29 FLRT2 NOTCH4 PEAR1

4.65e-0719715584e58bbf3ecb30b4c8199adcc04d2eb134d90de56
ToppCell10x5'v1-week_12-13-Endothelial-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 BOK ARHGAP29 SEMA6A FLRT2 AGRN NOTCH4

4.83e-071981558122215d9288533ad03562cf777e846504863df9a
ToppCell10x5'v1-week_12-13-Endothelial|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 BOK ARHGAP29 SEMA6A FLRT2 AGRN NOTCH4

4.83e-071981558307dd09e6bc820a148f3000f18dae7aedba4be0b
ToppCellCOVID-19-lung-Fibroblast|lung / Disease (COVID-19 only), tissue and cell type

EMILIN1 RYR2 FBN1 PTPRD HMCN1 PTPRS LSAMP SDK1

4.83e-071981558df3de77216f5c5d6141ec44d01c56b942f611838
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

FAT4 EMILIN1 RYR2 FBN1 HMCN1 PTPRS LSAMP SDK1

5.02e-0719915584bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FAT4 RYR2 FBN1 HMCN1 PTPRS LSAMP FLRT2 SDK1

5.21e-072001558cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellAdult-Mesenchymal-chondrocyte|Adult / Lineage, Cell type, age group and donor

EMILIN1 RYR2 HAUS4 FBN1 HMCN1 PTPRS LSAMP

1.45e-0615915573f7305ee76447064b5c846c4f576360a2f7e0b7c
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

KLK10 SEMA6D PTPRF SLC15A2 ARHGAP44 AGRN PLXNB1

3.18e-0617915571603117b52623663458a977c94bf7f9f6c1114b8
ToppCellControl-Endothelial_cells-Capillary_endothelial_cells|Control / group, cell type (main and fine annotations)

ROBO4 APP EEPD1 ARHGAP29 SEMA6A NDRG4 NOTCH4

3.30e-061801557b043f9ffb9a4cd427a15bebb86a711c7b08866e8
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO4 PDPR KIF26A CCT6A ATP11A SEMA6A PEAR1

3.42e-061811557fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF SLC15A2 ARHGAP44 PKHD1 TMPRSS2 PRDM16 AGRN

3.42e-061811557b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellPND07-28-samps-Endothelial-Postnatal_endothelial-capillary_endothelial_Hpgd-CA4_high|PND07-28-samps / Age Group, Lineage, Cell class and subclass

ROBO4 IMPDH1 SEMA6D ARHGAP29 SEMA6A KIT NOTCH4

3.42e-0618115579cd5e5c285c2b628db9d59709af053defd7c0aff
ToppCelldroplet-Marrow-BM-1m-Lymphocytic-naive_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYC IMPDH1 PFAS SUCLG2 EMILIN1 FBP1 PYCR3

3.95e-0618515573f1aa91efae2d00320d126087cce1431ad5f26ea
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

FBN1 BOK PTPRD SEMA6D STARD9 LSAMP UNC80

3.95e-0618515579f19f04fc4d97dfc2dd78cde77b515f1cb5d51ec
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF SLC15A2 ARHGAP44 PKHD1 TMPRSS2 ATP11A PRDM16

3.95e-061851557c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCell10x5'v1-week_12-13-Endothelial-stroma-sinusoidal_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 BOK HMCN1 ARHGAP29 FLRT2 NOTCH4

4.09e-061861557e8ead5634686ebaa6a230eea69795d923ce9939d
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

MYC FAT4 RYR2 PTPRD SEMA6D SEMA6A FLRT2

4.09e-0618615577def03dd856b765bd3f493288641981c4f7fd26e
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PTPRF SLC15A2 ARHGAP44 PKHD1 TMPRSS2 ATP11A PRDM16

4.09e-0618615573aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellfacs-Marrow-KLS-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYC IMPDH1 SUCLG2 EMILIN1 CCT6A KIT LSM7

4.71e-061901557a513c1e7df62c28128c932a68b252ee8f0255172
ToppCellLPS-IL1RA-Endothelial-Endothelial-Artery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KIF26A ANGEL1 FBN1 HMCN1 PRDM16 NDRG4 NOTCH4

4.71e-061901557aed65d584ca0c25f6a8313c66b421a6618af82ea
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

ROBO4 EMILIN1 ARHGAP29 SEMA6A FLRT2 NOTCH4 PEAR1

4.71e-061901557bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

ROBO4 EMILIN1 ARHGAP29 SEMA6A FLRT2 NOTCH4 PEAR1

4.71e-06190155708437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCell3'-Child04-06-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ROBO4 KLK10 KIF26A APP ARHGAP29 PRDM16 NOTCH4

4.71e-061901557ec6b8e2852e1cce0217ff61243defe98b2351640
ToppCellEndothelial-A-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

SELE ROBO4 FAT4 FBN1 NDRG4 NOTCH4 PEAR1

4.87e-061911557f702dfe88a9b04091dae87df61b2b4f43525f86a
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ROBO4 IMPDH1 ADGRE2 HMCN1 SEMA6A KIT NOTCH4

4.87e-06191155738fe60a8570f3c6eb8e8f8646f90d505dfd7d647
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

SELE ROBO4 FBN1 ARHGAP29 FLRT2 AGRN NOTCH4

4.87e-061911557cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellfacs-Lung-3m-Endothelial-capillary_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ROBO4 IMPDH1 ADGRE2 HMCN1 SEMA6A KIT NOTCH4

4.87e-0619115570e6cd2628a5cebd35e960e4eb3b52ddc9358031c
ToppCellLPS-antiTNF-Endothelial-Endothelial-Artery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ANGEL1 FBN1 HMCN1 PRDM16 NDRG4 NOTCH4

4.87e-0619115574b3d5157344dbfbf4fab518611cd9fa37fac7bd9
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FAT4 RYR2 FBN1 HMCN1 PTPRS LSAMP SDK1

4.87e-0619115576688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellLPS-antiTNF-Endothelial-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROBO4 FAT4 EEPD1 ARHGAP29 SEMA6A KIT NOTCH4

5.22e-06193155702f633b016ab19bfa65bfd0cf32f000549a62148
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

FAT4 ANGEL1 PTPRD HMCN1 SEMA6A KIT NOTCH4

5.22e-061931557e1d546165dcc2392f540162206852c4717d7306f
ToppCelltumor_Lung-Endothelial_cells-Stalk-like_ECs|tumor_Lung / Location, Cell class and cell subclass

SELE ROBO4 APP ARHGAP29 SEMA6A NDRG4 NOTCH4

5.22e-06193155721fec35587ffb5c0157e54a821ce3ffd3e24e536
ToppCellLPS-antiTNF-Endothelial|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ROBO4 FAT4 EEPD1 ARHGAP29 SEMA6A KIT NOTCH4

5.22e-0619315575122b1ffba42de190061be34ecdc6176f84e56a3
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ROBO4 FAT4 KIF26A EMILIN1 SEMA6A KIT PEAR1

5.22e-061931557d485634c564b268e344b6a2863c26f6adaec9e38
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

EMILIN1 RYR2 FBN1 HMCN1 PTPRS LSAMP SDK1

5.22e-061931557ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAT4 EMILIN1 RYR2 FBN1 HMCN1 LSAMP SDK1

5.40e-061941557011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

EMILIN1 RYR2 FBN1 PTPRD HMCN1 LSAMP SDK1

5.40e-06194155735f132cc38ac133be01834ed0946188aa0757eb4
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROBO4 FAT4 ARHGAP29 SEMA6A KIT NDRG4 NOTCH4

5.40e-06194155768004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EMILIN1 RYR2 FBN1 PTPRD PTPRS LSAMP SDK1

5.40e-0619415576e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCelldroplet-Lung-nan-18m-Endothelial-Capillary_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IMPDH1 ADRB2 HMCN1 ARHGAP29 SEMA6A KIT NOTCH4

5.40e-061941557faaa7f18667e8943528fd0e92b7988e5b0607b54
ToppCellfacs-Lung-18m-Endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ROBO4 IMPDH1 ADGRE2 HMCN1 ARHGAP29 SEMA6A KIT

5.40e-0619415573b5ba12375102598468cb09e66af9241b66c3cf9
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ROBO4 ADGRE2 HMCN1 ARHGAP29 SEMA6A KIT NOTCH4

5.40e-06194155744c7d4b75f3b7c9301eba20610e548a01a84ae40
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ROBO4 ADGRE2 HMCN1 ARHGAP29 SEMA6A KIT NOTCH4

5.40e-0619415577f24023df47935286f185dd428d48797daf26f49
ToppCellASK440-Endothelial-Endothelium|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

SELE ROBO4 FAT4 MUC19 ARHGAP29 NDRG4 NOTCH4

5.58e-061951557304f0dc91bb57e98b0ca31d6bfb3ff9364e4da56
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD177 MUC19 THSD7B FBN1 PTPRD HMCN1 UNC80

5.58e-061951557d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

CD177 MUC19 THSD7B FBN1 PTPRD HMCN1 UNC80

5.58e-06195155719853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

EMILIN1 RYR2 FBN1 HMCN1 PTPRS LSAMP SDK1

5.58e-06195155761c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellChildren_(3_yrs)-Endothelial|Children_(3_yrs) / Lineage, Cell type, age group and donor

ROBO4 FAT4 APP ARHGAP29 SEMA6A NDRG4 NOTCH4

5.58e-061951557094cf6591daa5ffad36e44122b6f524a3a34c2fd
ToppCellASK428-Endothelial-Endothelium|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

SELE ROBO4 ARHGAP29 SEMA6A NOTCH4 PEAR1 CHST3

5.77e-061961557b1a81eddb91fb462360692b7b0a3ba4a947eac40
ToppCelldroplet-Kidney-nan-3m-Epithelial|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OAT APP SUCLG2 BPNT1 KIDINS220 PTPRD PTPRF

5.77e-0619615579f39cb3de886283da34ee7511a92d94930a6c851
ToppCellbackground-Endothelial_cells|background / Sample and Cell Type and Tumor Cluster (all cells)

ROBO4 THSD7B APP ARHGAP29 SEMA6A FLRT2 NOTCH4

5.77e-061961557e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCellASK454-Endothelial|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

SELE ROBO4 FAT4 APP ARHGAP29 NOTCH4 PEAR1

5.77e-06196155714dd6956ef420b660be0baf52a66960e57d75d16
ToppCellCOVID-19-lung-Capillary_Aerocytes|lung / Disease (COVID-19 only), tissue and cell type

ROBO4 APP STARD9 ARHGAP29 SEMA6A NDRG4 NOTCH4

5.77e-0619615574ac4073380d939a73cec7413e9f3f5ef616d2924
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MROH5 PTPRF SLC15A2 PKHD1 TMPRSS2 ATP11A PLXNB1

5.97e-061971557b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCelltumor_Lung-Endothelial_cells|tumor_Lung / Location, Cell class and cell subclass

SELE ROBO4 APP ARHGAP29 SEMA6A NOTCH4 PEAR1

5.97e-0619715576870b311c54a73723768276a58456620f5217d43
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FAT4 EMILIN1 RYR2 PTPRD HMCN1 PTPRS LSAMP

5.97e-06197155794a9603cbd3516fbcce871909693b88f20d41713
ToppCellCOVID-19-Fibroblasts-Intermediate_pathological_FB|COVID-19 / group, cell type (main and fine annotations)

EMILIN1 RYR2 FBN1 PTPRD HMCN1 LSAMP SDK1

5.97e-061971557f1c8936986123a3151140c374fcd62d6705c530b
ToppCellCOVID-19-lung-Macrophage_VCANhi_FCN1hi|lung / Disease (COVID-19 only), tissue and cell type

PIK3AP1 CPPED1 CD177 NAIP ADGRE2 SLC24A4 OTOF

5.97e-061971557a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell356C-Endothelial_cells|356C / Donor, Lineage, Cell class and subclass (all cells)

SELE ROBO4 APP ARHGAP29 SEMA6A NDRG4 NOTCH4

5.97e-061971557f20eda534b2b28986790b28ce150ca3ba067593a
ToppCellCOVID-19-Fibroblasts|COVID-19 / group, cell type (main and fine annotations)

EMILIN1 RYR2 FBN1 HMCN1 PTPRS LSAMP SDK1

5.97e-061971557fb847f2277609c31fffcdf49517243ce0684facf
ToppCell390C-Endothelial_cells|390C / Donor, Lineage, Cell class and subclass (all cells)

SELE ROBO4 APP ARHGAP29 SEMA6A NOTCH4 PEAR1

5.97e-061971557aa381acea0f7882d39435a6f713386bf0588b5f8
ToppCellEndothelial-A|World / lung cells shred on cell class, cell subclass, sample id

SELE ROBO4 ARHGAP29 SEMA6A NDRG4 NOTCH4 PEAR1

6.17e-061981557dd096d4b9f428615f927f7df7cbf5cede0e0e605
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

EMILIN1 RYR2 FBN1 HMCN1 PTPRS LSAMP SDK1

6.17e-0619815573ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCelltumor_Lung-Endothelial_cells-Tumor_ECs|tumor_Lung / Location, Cell class and cell subclass

SELE ROBO4 APP ARHGAP29 SEMA6A NOTCH4 PEAR1

6.17e-0619815575228c4bf2513186140c2c4eaa67a268c732bdc84
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

FBP1 PTPRF SLC15A2 PKHD1 TMPRSS2 ATP11A PLXNB1

6.17e-06198155785f424cd9bb3117c9e322031024aabb87696ce47
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ROBO4 APP EEPD1 ARHGAP29 SEMA6A NDRG4 NOTCH4

6.17e-061981557a1ccbf0e653b2dd665c2254920eb9b37243cc0bd
ToppCellAdult-Mesenchymal|Adult / Lineage, Cell type, age group and donor

EMILIN1 RYR2 FBN1 HMCN1 PTPRS LSAMP SDK1

6.17e-06198155726e55b409db2a1637c95fae7c54b0abea1ef550c
ToppCellASK428-Endothelial|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ROBO4 FAT4 APP ARHGAP29 SEMA6A FLRT2 NOTCH4

6.17e-061981557d69d0ff115298596173a4278897a65007a71f5df
ToppCellTransplant_Alveoli_and_parenchyma-Endothelial|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

SELE ROBO4 ARHGAP29 SEMA6A NDRG4 NOTCH4 PEAR1

6.17e-06198155756b746e5791b47fe33a7872f0942ae0747b13d4a
ToppCellEndothelial_cells|World / lung cells shred on cell class, cell subclass, sample id

SELE ROBO4 ARHGAP29 SEMA6A NDRG4 NOTCH4 PEAR1

6.17e-061981557b93effa428ec036542fa21647dfef9589c64640f
ToppCellParenchymal-NucSeq-Endothelial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ROBO4 APP EEPD1 ARHGAP29 SEMA6A NDRG4 NOTCH4

6.37e-061991557a4a9a1c2a34b5a8318a55d1211d6c8661ca9793e
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SELE ROBO4 HMCN1 ARHGAP29 KIT NOTCH4 PEAR1

6.37e-061991557d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FBP1 PTPRF SLC15A2 PKHD1 TMPRSS2 ATP11A PLXNB1

6.37e-061991557d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_1|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

FBP1 PTPRF SLC15A2 PKHD1 TMPRSS2 ATP11A PLXNB1

6.37e-0619915571c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SELE ROBO4 HMCN1 ARHGAP29 KIT NOTCH4 PEAR1

6.37e-061991557cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCellParenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ROBO4 APP EEPD1 ARHGAP29 SEMA6A NDRG4 NOTCH4

6.37e-061991557dc88ce36cc066eb6c28cfd5b9b60fe07f8cc7b53
Drugphenylthiocarbamide

IMPDH1 OAT PFKP KIDINS220 FBP1 HYLS1 PYCR3

7.32e-07761517CID000676454
DiseaseCiliopathies

IMPDH1 TRIM32 NEK8 XPNPEP3 PKHD1 HYLS1

2.42e-051101536C4277690
Diseaseinterstitial lung disease

SPAG1 THSD7B FCRL6 ATP11A NOTCH4

2.62e-05671535EFO_0004244
Diseaseglycerate measurement

THSD7B HMCN1 AGRN

5.94e-05151533EFO_0021029
Diseasehereditary spastic paraplegia (implicated_via_orthology)

ATP13A5 ATP13A2 CAPN11 PNPLA7

7.33e-05431534DOID:2476 (implicated_via_orthology)
DiseaseDisorder of eye

IMPDH1 OAT ATP13A2 EYS TRIM32 PITPNM3 MFSD8

1.25e-042121537C0015397
Diseasejuvenile-onset Parkinson's disease (implicated_via_orthology)

ATP13A5 ATP13A2

1.59e-0441532DOID:0060893 (implicated_via_orthology)
DiseaseKufor-Rakeb syndrome (implicated_via_orthology)

ATP13A5 ATP13A2

1.59e-0441532DOID:0060556 (implicated_via_orthology)
DiseaseAlzheimer disease, polygenic risk score

ERCC2 ATG13 MUC19 ECHDC3 SF3B3 SLC24A4 PKHD1 LSAMP HADHA FLRT2 SDK1

2.54e-0458615311EFO_0030082, MONDO_0004975
DiseaseEndometrial Stromal Sarcoma

NUTM2A NUTM2B

2.64e-0451532C0206630
Diseaseazoospermia (implicated_via_orthology)

PTPRD PTPRF PTPRS

3.65e-04271533DOID:14227 (implicated_via_orthology)
DiseaseClear cell sarcoma of kidney

NUTM2E NUTM2B

3.95e-0461532C0334488
DiseaseHirschsprung's disease (is_marker_for)

HDAC8 KIT

3.95e-0461532DOID:10487 (is_marker_for)
Diseaselumbar disc degeneration

PFKP EYS CHST3

4.07e-04281533EFO_0004994
Diseasesusceptibility to mononucleosis measurement

FAT4 RYR2 PTPRD CNDP2

4.62e-04691534EFO_0008403
DiseaseAortic Aneurysm, Thoracic

ROBO4 FBN1

5.51e-0471532C0162872
DiseaseAortic Aneurysm, Thoracoabdominal

ROBO4 FBN1

5.51e-0471532C0340630
Diseasefatty liver disease (is_implicated_in)

ADRB2 HADHA

5.51e-0471532DOID:9452 (is_implicated_in)
Diseaseblood viscosity

SUCLG2 PTPRD PTPRF

5.52e-04311533EFO_0004301
Diseaseskin pigmentation measurement

FBN1 SEMA6D SLC24A4 ATP11A SDK1

7.57e-041371535EFO_0007009
Diseaselate-onset Alzheimers disease

PSMC6 APP ECHDC3 SLC24A4 HMCN1 PTPRS AGRN

8.58e-042921537EFO_1001870
DiseaseHereditary Diffuse Gastric Cancer

MYC FAT4 ERCC2 KLK10 ADRB2 FBP1 PTPRF

8.75e-042931537C1708349
Diseaseobesity (implicated_via_orthology)

FAT4 CAPN11 SLC15A2 SDK1 PLXNB1 NOTCH4

9.26e-042151536DOID:9970 (implicated_via_orthology)
DiseaseStomach Neoplasms

MYC FAT4 ERCC2 KLK10 ADRB2 FBP1 PTPRF

9.46e-042971537C0038356
DiseaseMalignant neoplasm of stomach

MYC FAT4 ERCC2 KLK10 ADRB2 FBP1 PTPRF

1.00e-033001537C0024623
Diseasebiological sex

ADD1 SEMA6D PKHD1 LSAMP SEMA6A SDK1

1.31e-032301536PATO_0000047
DiseaseMachado-Joseph disease, age at onset

THSD7B ATP11A

1.42e-03111532EFO_0004847, MONDO_0007182
Diseasephosphatidylcholine 32:0 measurement

ZC3HC1 PTPRD

1.42e-03111532EFO_0010372
DiseaseCystic Kidney Diseases

DNAJB11 FAT4

1.42e-03111532C1691228
DiseaseNephronophthisis

NEK8 XPNPEP3

2.01e-03131532C0687120
Diseasesmoking behavior

NRAP THSD7B SEMA6D PTPRF PKHD1 SDK1 CHST3

2.08e-033411537EFO_0004318
Diseaseneuronal ceroid lipofuscinosis (implicated_via_orthology)

ATP13A5 ATP13A2

2.33e-03141532DOID:14503 (implicated_via_orthology)
DiseaseLeft ventricular noncompaction

MIB1 PRDM16

2.33e-03141532C1960469
Diseaseacute graft vs. host disease, donor genotype effect measurement

EYS SDK1

2.68e-03151532EFO_0004599, EFO_0007892
Diseasehemorheological measurement

PTPRD LSAMP

2.68e-03151532EFO_0803374
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

NEK8 PKHD1

3.06e-03161532DOID:0110861 (implicated_via_orthology)
Diseaseurate measurement, spine bone mineral density

PTPRD LSAMP SLC27A5

3.42e-03581533EFO_0004531, EFO_0007701
DiseaseMalignant neoplasm of skin

ERCC2 KIT NOTCH4

3.59e-03591533C0007114
DiseaseSkin Neoplasms

ERCC2 KIT NOTCH4

3.59e-03591533C0037286
Diseaseserum IgG measurement

TRAF3 PDHB

3.87e-03181532EFO_0004565
Diseaseattention deficit hyperactivity disorder, Cannabis use

SEMA6D PTPRF

3.87e-03181532EFO_0003888, EFO_0007585
Diseasecolorectal health

XIRP1 RYR2 EYS PITPNM3 LSAMP

4.05e-032011535EFO_0008460
Diseaseexercise test

RYR2 PTPRD

4.77e-03201532EFO_0004328
Diseaseage at initiation of smoking

ADD1 LSAMP SDK1

4.93e-03661533EFO_0021784

Protein segments in the cluster

PeptideGeneStartEntry
FILPQNGVVEDVCVM

SYT13

131

Q7L8C5
CVVPGAGAVEVAMAE

CCT6A

406

P40227
PEVFGNLNSVMCVEG

NAIP

456

Q13075
FGIDMDSRICIVGPN

ABCF1

646

Q8NE71
ACADLVMGLAVVPFG

ADRB2

76

P07550
GQLPAVGRSMCVEIS

ATG13

71

O75143
GIVGVMATNIPCEVV

CFAP43

66

Q8NDM7
CVVNEGMLTGESIPV

ATP13A5

306

Q4VNC0
AGLLAEPQIAMFCGR

APP

26

P05067
CLGILQVGPAARVMA

ADGRE2

746

Q9UHX3
TPDIMCGRVQCENVG

ADAM20

556

O43506
CGNMAGRIEFNPIRV

CSRNP2

251

Q9H175
VGCIMEFAVNGRPLE

FAT4

4131

Q6V0I7
PQGAVRDDCEQMTGL

AGRN

851

O00468
RMAEIAAAGQVPCQG

CAMTA2

651

O94983
VQAERPDTMLGVVCG

ACACA

621

Q13085
PEERMNGQVVCAVPH

CSDE1

96

O75534
NVACIRTGIIFMPGT

ACSM4

131

P0C7M7
EAQQRVGGCFLNLMP

ARHGEF7

341

Q14155
TQEIGPVGMTENCNR

CD177

191

Q8N6Q3
FIMDGISPTDICQGI

CAPN11

121

Q9UMQ6
AGDIFAEVMVCRVLP

CCNP

81

Q9H8S5
GNLMVVQPDRIRCGA

PIK3AP1

176

Q6ZUJ8
CVAAMNPDAVLRVGG

BPNT1

206

O95861
AGLAVDCVRQAQPAM

BOK

131

Q9UMX3
GASAGVLMIQPCALD

CBY3

226

A6NI87
SLNVRGFMCQGPEQV

FLRT2

331

O43155
ANNPGVREVVCMTLL

EEPD1

276

Q7L9B9
REMLPQQVGFVCAVL

SLC24A4

16

Q8NFF2
PDCMASLIVARQGLG

SLC24A4

501

Q8NFF2
ARGCQFLGPAMQEEA

RC3H2

186

Q9HBD1
MQLAVDVQIPECFGG

RAD51C

136

O43502
VPRAGMCVVAVNGLL

IPP

521

Q9Y573
NISMCQALGFILGPV

MFSD8

171

Q8NHS3
LPIIGVVENMSGFIC

NUBP1

221

P53384
VGAEICARIMEGPAF

PDHB

301

P11177
ECGQTPLMIAAEQGN

KIDINS220

36

Q9ULH0
MAIENEPVGFQGCIR

EYS

2856

Q5T1H1
LVNGMLQCVAAGFPE

KIT

421

P10721
SDLNFMRGVACVIPG

NRAP

1171

Q86VF7
GDMVQLLCEAQRGSP

FCRL6

221

Q6DN72
PVIAMVNGLAAAAGC

ECHDC3

141

Q96DC8
NLEYCIMVIGVPNVG

MTG1

141

Q9BT17
DVLGMVTVAGVPCAV

PLXNB1

1101

O43157
MGNTSLVVPENCRGL

FAT2

3871

Q9NYQ8
GMVRNSKGICVFPND

MUC19

1221

Q7Z5P9
SMALPTQAQVVICGG

PDPR

36

Q8NCN5
CNVAVINVGAPAAGM

PFKP

411

Q01813
GAPCRIGIQEPFTVM

PEAR1

731

Q5VY43
CTMEVTPGAEIQDGR

FIP1L1

216

Q6UN15
MPPGQEAQRVVCGID

NEK8

491

Q86SG6
EEGFMLQGPAQVECT

SELE

336

P16581
CPMIIGRGNDQVAIS

ERCC2

491

P18074
MVGRGVPLCAAQPAV

KIF26A

1

Q9ULI4
RVLDVATCPGINMAA

LRRC29

181

Q8WV35
NMITGTAPLDGCILV

TUFM

136

P49411
TPGCVIAAARILQNM

MMEL1

91

Q495T6
LGGNCRTVMIAAISP

KIF18B

316

Q86Y91
ELSLGIGCPVNMVEV

OOSP4A

51

A0A2R8YFL7
DTCLFLTRPGEMVGQ

PNPLA7

516

Q6ZV29
EGNAVEIIMCNIRPC

HMCN1

4626

Q96RW7
SQGVGRPCMDINECE

HMCN1

5306

Q96RW7
CMAGARVQVTLDGVP

ICAM3

336

P32942
CITQEVMACGRPQGT

IMPDH1

331

P20839
DGTMCDTCRQQPIIG

MIB1

81

Q86YT6
IMPGGNVNITCVAVG

PTPRS

256

Q13332
GVNCFMLDPAIGEFI

FBP1

181

P09467
QPQDVMCSIGVVDQG

ARHGAP29

891

Q52LW3
TAVTVARGCGMVAPQ

ATP13A2

756

Q9NQ11
GCVVQASGLFPAEMR

FBXL19-AS1

86

Q494R0
QDRGAGPRVEMICQA

C17orf99

136

Q6UX52
DQLICSLQREGMGSP

HYLS1

166

Q96M11
REIPGVCENGVCINM

FBN1

1771

P35555
EAVQTGLPMCILGAF

COQ4

186

Q9Y3A0
ECRAVVIAGGTMQPV

DDX12P

631

Q92771
MVVSSAIGCQLGRDP

CPPED1

261

Q9BRF8
GPGRFQMTQEVVCDE

DNAJB11

181

Q9UBS4
CRGTSVVLICPQDGM

LSM7

76

Q9UK45
VMCLQEGILATPAEG

HADHA

686

P40939
PLQAGDTVCVDLVMG

EMILIN1

976

Q9Y6C2
GPEVMCLQTLNFGNG

ELP2

146

Q6IA86
VQDVGQVMPGANVCV

DIP2A

716

Q14689
VLQLGADTIAGDPMC

HDAC8

261

Q9BY41
FCSPGEGMEILQQVC

HAUS4

6

Q9H6D7
MVPEDGSLTCLQAGV

SEC14L4

346

Q9UDX3
MVPEDGILTCLQAGS

SEC14L6

346

B5MCN3
EETVDIGCQAMGVPL

SDK1

401

Q7Z5N4
ITPMLRGDVQCFGED

SLC15A2

201

Q16348
PVVEDVMTAGNCGNT

RXYLT1

351

Q9Y2B1
FIPVCSLGVAQVGRM

RYR2

1201

Q92736
GPRNCIGQSFAMAEL

CYP4F22

471

Q6NT55
LVGLNMDPVVCVEVG

OTOF

266

Q9HC10
QEVMPGGSVNLTCVA

PTPRF

241

P10586
EIMPGGSVNITCVAV

PTPRD

246

P23468
GILGMLCQDPDRATQ

MROH5

636

Q6ZUA9
PVMAAQVVGGTQACE

NUTM2A

256

Q8IVF1
PVMAAQVVGGTQACE

NUTM2B

256

A6NNL0
PVMAAQVVGGTQACE

NUTM2E

256

B1AL46
PLSVAMNCQGLIGVT

TRIM32

431

Q13049
QTFTIICGGPDIAMV

THAP8

236

Q8NA92
VRLDPDSGQTVLCGM

GFM2

521

Q969S9
RIVDGMFAVCGVPES

HARS2

216

P49590
GQCCNEFIMEGPLTR

SOS2

436

Q07890
AAPAICNGMLQGILS

PRSS58

196

Q8IYP2
CGNMSEAFREAGIQP

MELTF

36

P08582
ENCLEQLEMGFPRGA

LRRC41

586

Q15345
GSNVTLVCMANGRPE

LSAMP

146

Q13449
IGCQMVALNFQTPGL

PLCZ1

426

Q86YW0
LGGDMVNQSFICDPD

MYC

106

P01106
ADMQIVDGSAQCPGL

PRDM16

1096

Q9HAZ2
GGLMIPVFCVVEQLD

SATB2

56

Q9UPW6
APVMCILSGIGVSQV

STT3A

411

P46977
GMISRALFPDEVGCV

SLC5A9

336

Q2M3M2
CSPGQEAVLDQRMLG

TAOK2

776

Q9UL54
FSEMAPVCAVVGGIL

SAE1

296

Q9UBE0
RCPVMLVVGDNAPAE

NDRG4

226

Q9ULP0
PGRDCGLMVALQTQE

SWSAP1

131

Q6NVH7
ANIDIFIGMSPCVGV

PKHD1

1681

P08F94
ADGTFQGRCIPDMTQ

STARD9

1436

Q9P2P6
FVVVMGVDLSRCGPD

NOTCH4

1381

Q99466
ECGMQEEGLFRVAPS

ARHGAP44

281

Q17R89
VLPMNTGVEAGETAC

OAT

136

P04181
NLPCVVQEGAIVMAR

PYCR3

126

Q53H96
MVAVVGEQFTLECGP

ROBO4

146

Q8WZ75
CLGLLQVGPAAQVMA

ADGRE3

566

Q9BY15
IQTMCPIEGEGNIAR

AIMP2

201

Q13155
TAGPQSQVLCGVVMD

ADD1

516

P35611
ACQRPVGLVLMEGVT

ANGEL1

521

Q9UNK9
LAQVVQAACGPAMRL

CHST3

436

Q7LGC8
GQEIPVNVRFCLEGM

CNDP2

151

Q96KP4
ICNGQVLPESSGIDM

ATP11A

441

P98196
MAAPCEGQAFAVGVE

ZC3HC1

1

Q86WB0
VVCEGRPQVLSGRFM

PITPNM1

926

O00562
ILMDRSCNGPVLVGS

SUCLG2

156

Q96I99
PITSAMQGDRLGICV

EEFSEC

276

P57772
MQGDRLGICVTQFDP

EEFSEC

281

P57772
PDTMLQAAGCFVGVV

SPART

296

Q8N0X7
GEMNIASGCPVFVAQ

TRAF3

526

Q13114
TPAMICAGFLQGNVD

TMPRSS2

421

O15393
LAVPAVGARSGCVNM

ZNF618

911

Q5T7W0
CVNLVMGVVGPSSVA

UNC80

2641

Q8N2C7
EIIVNQACGGDMPAL

RNF208

71

Q9H0X6
MEAAEPVRDNQGFCI

SLC27A5

471

Q9Y2P5
EAEGRDPQGAMVICE

TONSL

301

Q96HA7
DPQGAMVICEQLGDL

TONSL

306

Q96HA7
FPRVAQVCKNDMGGS

SEMA6A

251

Q9H2E6
EMAFAGNCGLQVDVP

PFAS

921

O15067
AGAARAAQPCVMGNI

SPAG1

371

Q07617
VGVDVGFENPMFACL

SF3B3

171

Q15393
VLPRGMECVVFSIDG

PITPNM3

731

Q9BZ71
VSLGGGCNMIQPVNA

YY1AP1

611

Q9H869
VPAVANVRGLSGCML

XPNPEP3

11

Q9NQH7
QPCIIFMDEIDAIGG

PSMC6

226

P62333
GIAVFCEMVQFPGDV

TBCD

1091

Q9BTW9
GYENTPIMVCVDGIV

ZNF355P

21

Q9NSJ1
AGRVEDALCGEMPFQ

THSD7B

1341

Q9C0I4
VPRNDEMVFVCGTNA

SEMA6D

126

Q8NFY4
MAEVCPGGLQAAETT

XIRP1

1211

Q702N8
GNFVVDQMCEIGKPE

USP1

611

O94782
PGVVTNNMICAGLDR

KLK10

206

O43240