Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	LAMA2 HSPG2 PAPLN COMP SSPOP	6.31e-05	188	45	5	GO:0005201
GeneOntologyMolecularFunction	low-density lipoprotein particle receptor activity	LRP2 LRP6	5.84e-04	16	45	2	GO:0005041
GeneOntologyMolecularFunction	zinc ion binding	ERVK-5 KMT2A ADAMTS13 ZSWIM6 ST18 RNF207 ZMYM4 UBR4	7.55e-04	891	45	8	GO:0008270
GeneOntologyMolecularFunction	lipoprotein particle receptor activity	LRP2 LRP6	1.01e-03	21	45	2	GO:0030228
GeneOntologyMolecularFunction	BMP binding	BMPR2 COMP	1.11e-03	22	45	2	GO:0036122
GeneOntologyMolecularFunction	transition metal ion binding	ERVK-5 KMT2A ADAMTS13 ZSWIM6 F5 ST18 RNF207 ZMYM4 UBR4	1.16e-03	1189	45	9	GO:0046914
GeneOntologyBiologicalProcess	outflow tract morphogenesis	LRP2 LRP6 BMPR2 PLXND1	4.78e-05	94	44	4	GO:0003151
GeneOntologyBiologicalProcess	bone morphogenesis	LRP6 HSPG2 BMPR2 COMP	1.40e-04	124	44	4	GO:0060349
GeneOntologyBiologicalProcess	extracellular matrix organization	ADAMTS16 LAMA2 HSPG2 PAPLN ADAMTS13 COMP	1.41e-04	377	44	6	GO:0030198
GeneOntologyBiologicalProcess	extracellular structure organization	ADAMTS16 LAMA2 HSPG2 PAPLN ADAMTS13 COMP	1.43e-04	378	44	6	GO:0043062
GeneOntologyBiologicalProcess	external encapsulating structure organization	ADAMTS16 LAMA2 HSPG2 PAPLN ADAMTS13 COMP	1.45e-04	379	44	6	GO:0045229
GeneOntologyBiologicalProcess	artery development	LRP2 BMPR2 PLXND1 COMP	1.84e-04	133	44	4	GO:0060840
GeneOntologyBiologicalProcess	cardiac septum development	LRP2 LRP6 BMPR2 PLXND1	1.89e-04	134	44	4	GO:0003279
GeneOntologyCellularComponent	extracellular matrix	ADAMTS16 LAMA2 HSPG2 PAPLN ADAMTS13 COMP ZAN SSPOP	8.19e-05	656	46	8	GO:0031012
GeneOntologyCellularComponent	external encapsulating structure	ADAMTS16 LAMA2 HSPG2 PAPLN ADAMTS13 COMP ZAN SSPOP	8.37e-05	658	46	8	GO:0030312
GeneOntologyCellularComponent	clathrin-coated pit	LRP2 FNBP1 BMPR2	7.28e-04	80	46	3	GO:0005905
MousePheno	persistent truncus arteriosus type i	LRP2 BMPR2 PLXND1	1.85e-07	5	38	3	MP:0011661
MousePheno	abnormal ascending aorta and coronary artery attachment	HSPG2 PLXND1	2.15e-05	3	38	2	MP:0010472
MousePheno	abnormal thoracic cage morphology	TBX15 HMBOX1 LRP6 KMT2A HSPG2 BMPR2 SSPOP ST18	2.78e-05	463	38	8	MP:0004624
MousePheno	abnormal sacral vertebrae morphology	LRP6 KMT2A USP42 ST18	3.34e-05	68	38	4	MP:0003050
MousePheno	abnormal vertebral column morphology	TBX15 LAMA2 LRP6 KMT2A HSPG2 BMPR2 PLXND1 USP42 SSPOP ST18	3.38e-05	787	38	10	MP:0004703
MousePheno	abnormal joint morphology	LAMA2 LRP6 KMT2A HSPG2 BMPR2 PLXND1 COMP	8.33e-05	397	38	7	MP:0002932
MousePheno	abnormal vertebrae morphology	TBX15 LRP6 KMT2A HSPG2 BMPR2 PLXND1 USP42 ST18	8.92e-05	546	38	8	MP:0000137
MousePheno	abnormal cranium size	TBX15 LAMA2 LRP6 HSPG2	1.34e-04	97	38	4	MP:0010031
MousePheno	abnormal pectoral girdle bone morphology	TBX15 HMBOX1 KMT2A HSPG2 BMPR2 SSPOP	1.46e-04	301	38	6	MP:0004508
MousePheno	abnormal medium spiny neuron morphology	GPRIN3 ZSWIM6	1.99e-04	8	38	2	MP:0008462
MousePheno	abnormal ear morphology	TBX15 LRP2 LAMA2 LRP6 KMT2A HSPG2 ANKRD6	2.37e-04	470	38	7	MP:0002102
MousePheno	increased right ventricle systolic pressure	BMPR2 ERG	2.56e-04	9	38	2	MP:0010758
MousePheno	abnormal axial skeleton morphology	TBX15 HMBOX1 LRP2 LAMA2 LRP6 KMT2A HSPG2 BMPR2 PLXND1 USP42 SSPOP ST18	3.23e-04	1458	38	12	MP:0002114
MousePheno	perinatal lethality, incomplete penetrance	LRP2 LAMA2 LRP6 KMT2A HSPG2 BMPR2 F5	3.58e-04	503	38	7	MP:0011090
MousePheno	delayed bone ossification	TBX15 LRP6 HSPG2 BMPR2	3.78e-04	127	38	4	MP:0000060
MousePheno	abnormal cardiac outflow tract development	LRP2 HSPG2 BMPR2 PLXND1	4.63e-04	134	38	4	MP:0006126
MousePheno	abnormal thoracic aorta morphology	LRP2 HSPG2 BMPR2 PLXND1	4.63e-04	134	38	4	MP:0010468
MousePheno	skin hemorrhage	HSPG2 F5	4.67e-04	12	38	2	MP:0011514
MousePheno	short snout	LRP2 KMT2A HSPG2 PLXND1	4.89e-04	136	38	4	MP:0000445
MousePheno	decreased rib number	KMT2A BMPR2 ST18	4.90e-04	57	38	3	MP:0003345
MousePheno	abnormal sternum morphology	HMBOX1 KMT2A HSPG2 BMPR2 SSPOP	5.96e-04	255	38	5	MP:0000157
MousePheno	small snout	LRP2 KMT2A HSPG2 PLXND1	6.07e-04	144	38	4	MP:0030190
MousePheno	abnormal rib morphology	LRP6 KMT2A HSPG2 BMPR2 ST18	6.17e-04	257	38	5	MP:0000150
MousePheno	abnormal snout morphology	TBX15 LRP2 KMT2A HSPG2 PLXND1	6.17e-04	257	38	5	MP:0000443
MousePheno	pulmonary hypertension	BMPR2 ERG	6.41e-04	14	38	2	MP:0003548
MousePheno	perinatal lethality	TBX15 LRP2 LAMA2 LRP6 KMT2A HSPG2 BMPR2 PLXND1 F5 UBR4	6.65e-04	1130	38	10	MP:0002081
MousePheno	increased pulmonary artery pressure	BMPR2 ERG	7.39e-04	15	38	2	MP:0004012
MousePheno	abnormal myocardium compact layer morphology	LRP2 HSPG2 BMPR2	7.87e-04	67	38	3	MP:0004056
MousePheno	persistent truncus arteriosus	LRP2 BMPR2 PLXND1	7.87e-04	67	38	3	MP:0002633
MousePheno	abnormal aorticopulmonary septum morphology	LRP2 BMPR2 PLXND1	8.22e-04	68	38	3	MP:0010650
MousePheno	aorticopulmonary septal defect	LRP2 BMPR2 PLXND1	8.22e-04	68	38	3	MP:0010651
MousePheno	decreased chondrocyte proliferation	HSPG2 COMP	8.43e-04	16	38	2	MP:0014101
MousePheno	abnormal pulmonary pressure	BMPR2 ERG	9.54e-04	17	38	2	MP:0003547
Domain	LDLR_class-A_CS	LRP2 LRP6 HSPG2 SSPOP	2.76e-06	40	46	4	IPR023415
Domain	EGF_1	LRP2 LAMA2 LRP6 HSPG2 COMP ZAN SSPOP	2.77e-06	255	46	7	PS00022
Domain	EGF_2	LRP2 LAMA2 LRP6 HSPG2 COMP ZAN SSPOP	3.57e-06	265	46	7	PS01186
Domain	Ldl_recept_a	LRP2 LRP6 HSPG2 SSPOP	4.46e-06	45	46	4	PF00057
Domain	-	LRP2 LRP6 HSPG2 SSPOP	4.87e-06	46	46	4	4.10.400.10
Domain	TIL_dom	LRP2 ZAN SSPOP	4.99e-06	14	46	3	IPR002919
Domain	LDLRA_1	LRP2 LRP6 HSPG2 SSPOP	5.79e-06	48	46	4	PS01209
Domain	LDLRA_2	LRP2 LRP6 HSPG2 SSPOP	6.29e-06	49	46	4	PS50068
Domain	LDrepeatLR_classA_rpt	LRP2 LRP6 HSPG2 SSPOP	6.29e-06	49	46	4	IPR002172
Domain	LDLa	LRP2 LRP6 HSPG2 SSPOP	6.29e-06	49	46	4	SM00192
Domain	TSP_1	ADAMTS16 PAPLN ADAMTS13 SSPOP	1.72e-05	63	46	4	PF00090
Domain	TSP1	ADAMTS16 PAPLN ADAMTS13 SSPOP	1.95e-05	65	46	4	SM00209
Domain	TSP1_rpt	ADAMTS16 PAPLN ADAMTS13 SSPOP	1.95e-05	65	46	4	IPR000884
Domain	TSP1	ADAMTS16 PAPLN ADAMTS13 SSPOP	1.95e-05	65	46	4	PS50092
Domain	EGF_3	LRP2 LRP6 HSPG2 COMP ZAN SSPOP	2.29e-05	235	46	6	PS50026
Domain	EGF	LRP2 LAMA2 LRP6 HSPG2 COMP ZAN	2.29e-05	235	46	6	SM00181
Domain	Peptidase_M12B_ADAM-TS	ADAMTS16 PAPLN ADAMTS13	2.73e-05	24	46	3	IPR013273
Domain	EGF-like_dom	LRP2 LAMA2 LRP6 HSPG2 COMP ZAN	3.17e-05	249	46	6	IPR000742
Domain	EGF-like_CS	LRP2 LAMA2 LRP6 HSPG2 COMP ZAN	4.12e-05	261	46	6	IPR013032
Domain	LAMININ_IVA	LAMA2 HSPG2	1.65e-04	8	46	2	PS51115
Domain	Laminin_B	LAMA2 HSPG2	1.65e-04	8	46	2	PF00052
Domain	LamB	LAMA2 HSPG2	1.65e-04	8	46	2	SM00281
Domain	Laminin_IV	LAMA2 HSPG2	1.65e-04	8	46	2	IPR000034
Domain	DUF1220	NBPF4 NBPF6	2.11e-04	9	46	2	SM01148
Domain	EGF	LRP2 LRP6 HSPG2 ZAN	2.59e-04	126	46	4	PF00008
Domain	NBPF_dom	NBPF4 NBPF6	3.22e-04	11	46	2	IPR010630
Domain	Laminin_G_1	LAMA2 HSPG2	3.22e-04	11	46	2	PF00054
Domain	NBPF	NBPF4 NBPF6	3.22e-04	11	46	2	PS51316
Domain	DUF1220	NBPF4 NBPF6	3.22e-04	11	46	2	PF06758
Domain	TIL	ZAN SSPOP	3.86e-04	12	46	2	PF01826
Domain	C8	ZAN SSPOP	3.86e-04	12	46	2	PF08742
Domain	Unchr_dom_Cys-rich	ZAN SSPOP	4.55e-04	13	46	2	IPR014853
Domain	C8	ZAN SSPOP	4.55e-04	13	46	2	SM00832
Domain	PLAC	ADAMTS16 PAPLN	5.30e-04	14	46	2	PF08686
Domain	Ldl_recept_b	LRP2 LRP6	5.30e-04	14	46	2	PF00058
Domain	LDLRB	LRP2 LRP6	5.30e-04	14	46	2	PS51120
Domain	LY	LRP2 LRP6	6.11e-04	15	46	2	SM00135
Domain	LDLR_classB_rpt	LRP2 LRP6	6.11e-04	15	46	2	IPR000033
Domain	VWD	ZAN SSPOP	6.97e-04	16	46	2	SM00216
Domain	VWF_type-D	ZAN SSPOP	6.97e-04	16	46	2	IPR001846
Domain	VWFD	ZAN SSPOP	6.97e-04	16	46	2	PS51233
Domain	VWD	ZAN SSPOP	6.97e-04	16	46	2	PF00094
Domain	-	LAMA2 SSPOP F5	7.71e-04	73	46	3	2.60.120.260
Domain	VWC_out	ZAN SSPOP	9.88e-04	19	46	2	SM00215
Domain	PLAC	ADAMTS16 PAPLN	9.88e-04	19	46	2	PS50900
Domain	PLAC	ADAMTS16 PAPLN	9.88e-04	19	46	2	IPR010909
Domain	FA58C	SSPOP F5	1.21e-03	21	46	2	SM00231
Domain	FA58C_3	SSPOP F5	1.21e-03	21	46	2	PS50022
Domain	FA58C_1	SSPOP F5	1.21e-03	21	46	2	PS01285
Domain	FA58C_2	SSPOP F5	1.21e-03	21	46	2	PS01286
Domain	ADAM_spacer1	ADAMTS16 PAPLN	1.45e-03	23	46	2	IPR010294
Domain	ADAM_spacer1	ADAMTS16 PAPLN	1.45e-03	23	46	2	PF05986
Domain	F5_F8_type_C	SSPOP F5	1.58e-03	24	46	2	PF00754
Domain	FA58C	SSPOP F5	1.58e-03	24	46	2	IPR000421
Domain	Galactose-bd-like	LAMA2 SSPOP F5	1.60e-03	94	46	3	IPR008979
Domain	-	LAMA2 HSPG2 COMP	1.65e-03	95	46	3	2.60.120.200
Domain	ConA-like_dom	LAMA2 HSPG2 COMP ZAN	2.04e-03	219	46	4	IPR013320
Domain	EGF_LAM_2	LAMA2 HSPG2	2.47e-03	30	46	2	PS50027
Domain	EGF_LAM_1	LAMA2 HSPG2	2.47e-03	30	46	2	PS01248
Domain	Laminin_EGF	LAMA2 HSPG2	3.35e-03	35	46	2	PF00053
Domain	EGF_Lam	LAMA2 HSPG2	3.35e-03	35	46	2	SM00180
Domain	EGF_CA	LRP2 HSPG2 COMP	3.36e-03	122	46	3	SM00179
Domain	EGF-like_Ca-bd_dom	LRP2 HSPG2 COMP	3.52e-03	124	46	3	IPR001881
Domain	VWFC_1	ZAN SSPOP	3.54e-03	36	46	2	PS01208
Domain	VWC	ZAN SSPOP	3.94e-03	38	46	2	SM00214
Domain	VWFC_2	ZAN SSPOP	3.94e-03	38	46	2	PS50184
Domain	LAM_G_DOMAIN	LAMA2 HSPG2	3.94e-03	38	46	2	PS50025
Domain	Laminin_EGF	LAMA2 HSPG2	3.94e-03	38	46	2	IPR002049
Domain	-	LRP2 LRP6	4.15e-03	39	46	2	2.120.10.30
Domain	DISINTEGRIN_1	ADAMTS16 ADAMTS13	4.36e-03	40	46	2	PS00427
Domain	Reprolysin	ADAMTS16 ADAMTS13	4.36e-03	40	46	2	PF01421
Domain	Laminin_G_2	LAMA2 HSPG2	4.36e-03	40	46	2	PF02210
Domain	ADAM_MEPRO	ADAMTS16 ADAMTS13	4.36e-03	40	46	2	PS50215
Domain	DISINTEGRIN_2	ADAMTS16 ADAMTS13	4.36e-03	40	46	2	PS50214
Domain	Peptidase_M12B	ADAMTS16 ADAMTS13	4.36e-03	40	46	2	IPR001590
Domain	Disintegrin_dom	ADAMTS16 ADAMTS13	4.58e-03	41	46	2	IPR001762
Domain	VWF_dom	ZAN SSPOP	4.80e-03	42	46	2	IPR001007
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS16 ADAMTS13 SSPOP	6.11e-05	39	28	3	M27417
Pathway	REACTOME_O_GLYCOSYLATION_OF_TSR_DOMAIN_CONTAINING_PROTEINS	ADAMTS16 ADAMTS13 SSPOP	6.11e-05	39	28	3	MM15165
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	ADAMTS16 HSPG2 ADAMTS13 SSPOP	1.72e-04	143	28	4	M27275
Pathway	REACTOME_DISEASES_ASSOCIATED_WITH_O_GLYCOSYLATION_OF_PROTEINS	ADAMTS16 ADAMTS13 SSPOP	3.23e-04	68	28	3	M27303
Pathway	REACTOME_ECM_PROTEOGLYCANS	LAMA2 HSPG2 COMP	4.48e-04	76	28	3	M27219
Pathway	PID_BETA_CATENIN_DEG_PATHWAY	LRP6 SSPOP	5.71e-04	18	28	2	M31
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	LAMA2 HSPG2 COMP	6.00e-04	84	28	3	M7098
Pathway	REACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION	PLXND1 MAML3	1.11e-03	25	28	2	M27880
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS16 ADAMTS13 SSPOP	1.28e-03	109	28	3	MM15164
Pathway	REACTOME_O_LINKED_GLYCOSYLATION	ADAMTS16 ADAMTS13 SSPOP	1.35e-03	111	28	3	M27416
Pathway	REACTOME_DISEASES_OF_METABOLISM	ADAMTS16 HSPG2 ADAMTS13 SSPOP	1.41e-03	250	28	4	M27554
Pubmed	PTTG1IP and MAML3, novel genomewide association study genes for severity of hyperresponsiveness in adult asthma.	MAML3 PTTG1IP	1.87e-06	2	48	2	27709636
Pubmed	Potential role of cartilage oligomeric matrix protein in the modulation of pulmonary arterial smooth muscle superoxide by hypoxia.	BMPR2 COMP	1.87e-06	2	48	2	31389735
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF4 NBPF6 NBPF5P	3.22e-06	21	48	3	16079250
Pubmed	O-fucosylation of thrombospondin type 1 repeats restricts epithelial to mesenchymal transition (EMT) and maintains epiblast pluripotency during mouse gastrulation.	ADAMTS16 PAPLN ADAMTS13 SSPOP	3.61e-06	75	48	4	20637190
Pubmed	A genome-wide association study identifies two risk loci for congenital heart malformations in Han Chinese populations.	TBX15 MAML3	5.59e-06	3	48	2	23708190
Pubmed	Prefrontal dysfunction in schizophrenia involves mixed-lineage leukemia 1-regulated histone methylation at GABAergic gene promoters.	KMT2A DRD3	5.59e-06	3	48	2	17942719
Pubmed	ADAMTS-3, -13, -16, and -19 levels in patients with habitual abortion.	ADAMTS16 ADAMTS13	1.12e-05	4	48	2	28088271
Pubmed	Identification of interaction partners of the cytosolic polyproline region of CD95 ligand (CD178).	FNBP1 KMT2A	1.86e-05	5	48	2	12023017
Pubmed	Human transcription factor protein interaction networks.	HMBOX1 LRP2 LRP6 KMT2A HSPG2 CEP192 ERG ZMYM4 UBR4 ZNF507	2.09e-05	1429	48	10	35140242
Pubmed	Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.	LAMA2 HSPG2 ADAMTS13 PLXND1 F5	2.80e-05	257	48	5	16335952
Pubmed	Cloning, expression analysis, and structural characterization of seven novel human ADAMTSs, a family of metalloproteinases with disintegrin and thrombospondin-1 domains.	ADAMTS16 ADAMTS13	3.90e-05	7	48	2	11867212
Pubmed	Absence of acetylcholinesterase at the neuromuscular junctions of perlecan-null mice.	LAMA2 HSPG2	3.90e-05	7	48	2	11802174
Pubmed	The mutational landscape of lethal castration-resistant prostate cancer.	KMT2A ERG	5.19e-05	8	48	2	22722839
Pubmed	[Detection of fusion genes resulting from chromosome abnormalities in childhood acute lymphoblastic leukemia].	KMT2A ERG	8.33e-05	10	48	2	16215946
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	LAMA2 HSPG2 SSPOP	9.69e-05	64	48	3	22261194
Pubmed	A forward genetic screen in mice identifies mutants with abnormal cortical patterning.	LRP2 LRP6	1.02e-04	11	48	2	23968836
Pubmed	LRP2 mediates folate uptake in the developing neural tube.	LRP2 LRP6	1.02e-04	11	48	2	24639464
Pubmed	Tie2 regulates endocardial sprouting and myocardial trabeculation.	HSPG2 PLXND1 ERG	1.16e-04	68	48	3	31112136
Pubmed	Molecular dissection of laminin alpha 5 in vivo reveals separable domain-specific roles in embryonic development and kidney function.	LAMA2 HSPG2	1.22e-04	12	48	2	16750824
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 PAPLN CEP192 TTYH3 PLXND1 MLXIP MTG2 UBR4	1.24e-04	1105	48	8	35748872
Pubmed	Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.	LRP2 LAMA2 SSPOP	1.32e-04	71	48	3	33541421
Pubmed	Stage-specific association of apolipoprotein A-I and E in developing mouse retina.	LRP2 LRP6	1.68e-04	14	48	2	17389516
Pubmed	The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.	ERG UBR4	1.68e-04	14	48	2	27626314
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	HMBOX1 FNBP1 BMPR2 CEP192 TTYH3 ZSWIM6 SSPOP MAML3 ZMYM4	1.75e-04	1489	48	9	28611215
Pubmed	Transcriptome-based systematic identification of extracellular matrix proteins.	LAMA2 HSPG2 PAPLN	1.81e-04	79	48	3	18757743
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA2 HSPG2	1.94e-04	15	48	2	15895400
Pubmed	Perlecan maintains the integrity of cartilage and some basement membranes.	HSPG2 COMP	1.94e-04	15	48	2	10579729
Pubmed	Perinatal lethality and endothelial cell abnormalities in several vessel compartments of fibulin-1-deficient mice.	LAMA2 HSPG2	2.21e-04	16	48	2	11564885
Pubmed	Patterns of laminins and integrins in the embryonic ventricular zone of the CNS.	LAMA2 HSPG2	2.21e-04	16	48	2	17948866
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FNBP1 CEP192 ZSWIM6 MLXIP ST18	2.42e-04	407	48	5	12693553
Pubmed	PERP regulates enamel formation via effects on cell-cell adhesion and gene expression.	LAMA2 DMKN	3.14e-04	19	48	2	21285247
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	LRP2 UBQLN2 ERG ANKRD6 ST18 ZMYM4 UBR4 CEP57L1	3.44e-04	1285	48	8	35914814
Pubmed	Global genetic analysis in mice unveils central role for cilia in congenital heart disease.	LRP2 BMPR2 PLXND1	3.63e-04	100	48	3	25807483
Pubmed	MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.	LRP2 LRP6	3.85e-04	21	48	2	21337463
Pubmed	Schwann cell myelination requires integration of laminin activities.	LAMA2 HSPG2	3.85e-04	21	48	2	22767514
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	FNBP1 SSPOP ST18	4.19e-04	105	48	3	9628581
Pubmed	Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.	KMT2A DRD3 F5	4.55e-04	108	48	3	19956635
Pubmed	Conditional deletion of beta1-integrin in astroglia causes partial reactive gliosis.	LAMA2 HSPG2	5.48e-04	25	48	2	19373938
Pubmed	A large-scale candidate gene association study of age at menarche and age at natural menopause.	BMPR2 ADAMTS13 DRD3 F5	5.66e-04	275	48	4	20734064
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ADAMTS16 GPRIN3 TTYH3 ANKRD6 MAML3	5.81e-04	493	48	5	15368895
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FNBP1 KMT2A ERG USP42 ZMYM4 ZNF507	6.60e-04	774	48	6	15302935
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	LRP2 FNBP1 CEP192 SETX ANKRD6 CEP57L1 ZNF507	6.76e-04	1084	48	7	11544199
Pubmed	Genetic link between renal birth defects and congenital heart disease.	LRP2 PLXND1	6.89e-04	28	48	2	27002738
Pubmed	Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome-associated proteins.	LAMA2 HSPG2	7.39e-04	29	48	2	22613833
Pubmed	Genetic associations for activated partial thromboplastin time and prothrombin time, their gene expression profiles, and risk of coronary artery disease.	ADAMTS13 F5	9.58e-04	33	48	2	22703881
Pubmed	Amyotrophic Lateral Sclerosis Overview	SETX UBQLN2	9.58e-04	33	48	2	20301623
Pubmed	Large-scale identification of genes implicated in kidney glomerulus development and function.	LAMA2 HSPG2	1.02e-03	34	48	2	16498405
Pubmed	Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins.	LAMA2 HSPG2 COMP	1.09e-03	146	48	3	27068509
Pubmed	Proximity Mapping of CCP6 Reveals Its Association with Centrosome Organization and Cilium Assembly.	CEP192 CCDC66	1.27e-03	38	48	2	36674791
Pubmed	Assembly, verification, and initial annotation of the NIA mouse 7.4K cDNA clone set.	PIEZO2 RNF207 CEP57L1	1.34e-03	157	48	3	12466305
Pubmed	A gene expression map of human chromosome 21 orthologues in the mouse.	IGSF5 ERG PTTG1IP	1.37e-03	158	48	3	12466855
Cytoband	1p13.3	NBPF4 NBPF6 NBPF5P	5.35e-05	69	48	3	1p13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr1p13	NBPF4 NBPF6 NBPF5P	1.42e-03	211	48	3	chr1p13
Cytoband	9q34	FNBP1 ADAMTS13	1.48e-03	54	48	2	9q34
Cytoband	Ensembl 112 genes in cytogenetic band chr9q34	FNBP1 ADAMTS13 SETX	4.80e-03	325	48	3	chr9q34
Cytoband	Ensembl 112 genes in cytogenetic band chr21q22	IGSF5 ERG PTTG1IP	7.23e-03	377	48	3	chr21q22
Cytoband	21q22.3	ERG PTTG1IP	8.00e-03	128	48	2	21q22.3
Cytoband	Ensembl 112 genes in cytogenetic band chr7p22	TTYH3 USP42	8.74e-03	134	48	2	chr7p22
GeneFamily	Neuroblastoma breakpoint family	NBPF4 NBPF6 NBPF5P	9.57e-06	23	33	3	662
GeneFamily	Low density lipoprotein receptors	LRP2 LRP6	2.49e-04	13	33	2	634
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS16 ADAMTS13	5.42e-04	19	33	2	50
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	IGSF5 HSPG2 PAPLN	3.11e-03	161	33	3	593
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS16 LRP2 PIEZO2 ZAN SSPOP ST18	4.03e-08	184	47	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS16 LRP2 PIEZO2 ZAN SSPOP ST18	4.03e-08	184	47	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS16 LRP2 PIEZO2 ZAN SSPOP ST18	4.03e-08	184	47	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PIEZO2 PLXND1 ERG	1.87e-06	194	47	5	e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PIEZO2 PLXND1 ERG	1.97e-06	196	47	5	023312af38f816a44b407e0daa32590d953caf99
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PIEZO2 PLXND1 ERG	2.02e-06	197	47	5	cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PIEZO2 PLXND1 ERG	2.02e-06	197	47	5	412cb5f37df57121ddd1492021445479c7cbccbf
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PIEZO2 PLXND1 ERG	2.07e-06	198	47	5	31ba87552be97c9b78c9e82f98e96699ccb19824
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	HMBOX1 BMPR2 SETX ERG PTTG1IP	2.18e-06	200	47	5	bcd1cc96197929d6011903803b6f4ccdcf52b4ce
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	HMBOX1 KMT2A BMPR2 ERG PTTG1IP	2.18e-06	200	47	5	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HMBOX1 BMPR2 SETX ERG PTTG1IP	2.18e-06	200	47	5	79e51afb57ca38aacebd0298e5e727b55c0cfff9
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_2\|390C / Donor, Lineage, Cell class and subclass (all cells)	TTYH3 ZSWIM6 ST18 UBR4	2.15e-05	155	47	4	15bacd06cc2b02b13c85bb71c5b758e5ff613e80
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA2 PIEZO2 PLXND1 MAML3	2.69e-05	164	47	4	b6df1e67a5ce5f2d86f4e1420f4ee931f760bf4d
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HSPG2 BMPR2 DRD3 ERG	2.82e-05	166	47	4	f7926ee266dcbf10df375cd921f1db5a2fa604f8
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	LAMA2 PAPLN ADAMTS13 COMP	3.95e-05	181	47	4	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 GPRIN3 PLXND1 ERG	3.95e-05	181	47	4	9bfd93cf053beaee806cacdffd7abef02f94aec6
ToppCell	5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 PLXND1 ERG ZAN	4.03e-05	182	47	4	d0e3663f7d39f22a3ebd7fde56ab3504773598f4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	KMT2A GPRIN3 CCDC66 ZNF507	4.21e-05	184	47	4	5350b58aa9979631228835d11eb45ddf81d08bff
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 TTYH3 PLXND1 ERG	4.30e-05	185	47	4	602536a3308a848f106adcb0a83530997440c8f4
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	HSPG2 BMPR2 PLXND1 ERG	4.48e-05	187	47	4	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LAMA2 FNBP1 PAPLN ERG	4.67e-05	189	47	4	b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PAPLN BMPR2 PIEZO2 MLXIP	4.87e-05	191	47	4	08720998aa55131d7377c4c67c4c935865bd7d79
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	4.97e-05	192	47	4	eafead22bba48ac5ee568faa8946c444445c1034
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Vein\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HSPG2 PLXND1 ERG F5	4.97e-05	192	47	4	717f3d3bbee4d0f64ba1341ee2b00a407ba1e0f3
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 GPRIN3 PLXND1 ERG	4.97e-05	192	47	4	5a0615fdc217554ccd611504b16e5d97628e207d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 PIEZO2 PLXND1 ERG	4.97e-05	192	47	4	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	facs-Liver-Non-hepatocytes-3m\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 BMPR2 PLXND1 MLXIP	5.07e-05	193	47	4	8084fa0ce61f1f4a728423b6b81df04eaa5af5b6
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.07e-05	193	47	4	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	FNBP1 RCBTB2 TTYH3 PLXND1	5.07e-05	193	47	4	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 PIEZO2 PLXND1 ERG	5.07e-05	193	47	4	52e918884877b6659cdca0496390e440f73694a9
ToppCell	facs-Kidney-nan-3m-Endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 PIEZO2 PLXND1 ERG	5.17e-05	194	47	4	5fa2dfca32cca4abfda0af90b83f2b2a826f9b6e
ToppCell	facs-Kidney-nan-3m-Endothelial-fenestrated_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 PIEZO2 PLXND1 ERG	5.17e-05	194	47	4	04df35246287815bdd28adaf885bdb98cf49524e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.17e-05	194	47	4	f76808666fb875fc787751cbfd924d9be20a8192
ToppCell	facs-Kidney-nan-3m-Endothelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 PIEZO2 PLXND1 ERG	5.17e-05	194	47	4	90928d6c96c6304ae35dcc0275f7889de93da100
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	HSPG2 BMPR2 PLXND1 ERG	5.17e-05	194	47	4	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.17e-05	194	47	4	74a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D231\|Adult / Lineage, Cell type, age group and donor	FNBP1 RCBTB2 TTYH3 PLXND1	5.17e-05	194	47	4	800d3d7a9e864d2d6a100a4e4af22f45d5790a8d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.17e-05	194	47	4	f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.17e-05	194	47	4	a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FNBP1 HSPG2 BMPR2 ERG	5.27e-05	195	47	4	d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR2 PIEZO2 PLXND1 ERG	5.27e-05	195	47	4	23ced69fd904f1d4114b1a7f99f4b5f65ea8824b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.38e-05	196	47	4	8ad8efb631164b46f0c082572270188e5ead20bf
ToppCell	background-Endothelial_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	HSPG2 BMPR2 PIEZO2 ERG	5.38e-05	196	47	4	e6fb0bfab1779ec64a8c35d01519eaafbf62e977
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.38e-05	196	47	4	9606ea7e42f707e69ea891b3521037613b9675f5
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	BMPR2 PIEZO2 PLXND1 ERG	5.38e-05	196	47	4	65d882c6e7f6d5778b8a5fd4fdaf012e1b9f6100
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.38e-05	196	47	4	adee900dcd16dbaba15c58bdcace09ba20214950
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.38e-05	196	47	4	95c5b8fd4ebfae1f42de9b1475c1161d4a80e515
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LAMA2 PIEZO2 COMP F5	5.38e-05	196	47	4	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.38e-05	196	47	4	ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.38e-05	196	47	4	22767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.49e-05	197	47	4	61b1b10a017cbeb17f8529fcae66cba77ee2f115
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.49e-05	197	47	4	87eda06344498dc66cac292cf89746dc90b5cf67
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 BMPR2 PLXND1 MLXIP	5.49e-05	197	47	4	deefb492b5f0e6014144bd465c4a6ae4206e8739
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 BMPR2 PLXND1 MLXIP	5.49e-05	197	47	4	a6aaa6faea348291023f0bc4b0f83fbc67d91da6
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.49e-05	197	47	4	e8e879b7634a29569061d3515d180784094a31e7
ToppCell	5'-Adult-Distal_Rectal-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.60e-05	198	47	4	8d6b0b9da7c1e64155cbcbb04ad38d129a29030c
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LAMA2 HSPG2 PIEZO2 COMP	5.60e-05	198	47	4	4f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.60e-05	198	47	4	07701c73137947ed4a27e225975329235bbb8734
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.60e-05	198	47	4	13203249e5743ba2699871c184d141207e550a86
ToppCell	Non-neuronal-Postmitotic-Mural\|World / Primary Cells by Cluster	LAMA2 HSPG2 PLXND1 ERG	5.60e-05	198	47	4	dd38840a96171f58da243daa22b013e15a81db4a
ToppCell	3'-Pediatric_IBD-SmallIntestine-Endothelial-blood_vessel_EC\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.60e-05	198	47	4	5b86dc00acf8ac2ede008f5d79c09996485bf250
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.60e-05	198	47	4	fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.60e-05	198	47	4	0a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCell	Non-neuronal-Postmitotic-Mural-Mural\|World / Primary Cells by Cluster	LAMA2 HSPG2 PLXND1 ERG	5.60e-05	198	47	4	9fc1035ea447a4551a66944c869c4671e17cec61
ToppCell	5'-Adult-Distal_Rectal-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.60e-05	198	47	4	d1f54ed3ef5e05ebda7da999e172d168dc6802cd
ToppCell	facs-Liver-Non-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 BMPR2 PLXND1 MLXIP	5.60e-05	198	47	4	f0f1816a0ed3ae8207442602f5cbe4de0382e4b3
ToppCell	Non-neuronal-Postmitotic-Mural-Mural-18\|World / Primary Cells by Cluster	LAMA2 HSPG2 PLXND1 ERG	5.60e-05	198	47	4	21efb7bcd24f24d20791b34e75d6f9d46a129481
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.60e-05	198	47	4	259fbcc0f2ac281a3e4d693de45b986fe5e24841
ToppCell	wk_20-22-Endothelial-Blood_vessel_endothelial-Venous_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	70e05d7c0c68c28754ce0e72434b205aed6287ae
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	07bda4ac8ffdce1a865ebc99e46c2a27925ff7a8
ToppCell	Non-neuronal-Postmitotic-Endothelial\|World / Primary Cells by Cluster	LAMA2 HSPG2 PLXND1 ERG	5.71e-05	199	47	4	b9763ac9857a60db6f1f104fe1e9ea2266cf931b
ToppCell	Non-neuronal-Postmitotic-Endothelial-Endothelial-24\|World / Primary Cells by Cluster	LAMA2 HSPG2 PLXND1 ERG	5.71e-05	199	47	4	0b4edf3e359749827ef978a77b5267ddde732d71
ToppCell	PBMC-Control-cDC_0\|Control / Compartment, Disease Groups and Clusters	TTYH3 PLXND1 F5 UBR4	5.71e-05	199	47	4	ebf03979ef56e978d72db475bb635b43b9cbe402
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	8b62d43af8b2ebb4c1b2d068d50beaf35728dbe7
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	14e09eaa2335d4503de50250eb4258dd5b85b304
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	d95d78b2ebc9a20532466e4d4be579b4faf6776f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	da5a88749d859d535daa030d0974485906cc0ba7
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	33f1669eeb701986b4dec409efdb6c06c3c41c2b
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	f35e9c05d0a0339ff691b38564da7aad8e9218aa
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Scavenging_endothelial-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	cdcfca94baba66e213cc3ffb0cfb4c75d6ab44ec
ToppCell	5'-Adult-LargeIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	ffebd99d55d31cf51b4878b2690ed0b9b3799223
ToppCell	5'-Adult-LargeIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.71e-05	199	47	4	258d59cf811bf1668ffbb5f18f961021f660de62
ToppCell	Non-neuronal-Postmitotic-Endothelial-Endothelial\|World / Primary Cells by Cluster	LAMA2 HSPG2 PLXND1 ERG	5.71e-05	199	47	4	9e01eee126247a0696c71b019f855a8a41a0ede3
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.82e-05	200	47	4	cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.82e-05	200	47	4	2e47888e041ec3d265425d1df97b6665c6da889c
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	KMT2A BMPR2 SETX ERG	5.82e-05	200	47	4	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.82e-05	200	47	4	3007583eaad3a5ae2df010513d3e4df59155123d
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	LRP2 PAPLN TTYH3 UBR4	5.82e-05	200	47	4	105564ee05bd11685b5747ee32d5350cf3c2e2e1
ToppCell	5'-Adult-SmallIntestine-Endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPG2 BMPR2 PLXND1 ERG	5.82e-05	200	47	4	2554b77edfe3d378296b0b25625caacbfb1c0e76
ToppCell	Control_saline-Endothelial-Endothelial-Activated_Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	BMPR2 SETX ERG PTTG1IP	5.82e-05	200	47	4	be55cef682ba87250dad97689332c8820b3a7420
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	BMPR2 SETX ERG PTTG1IP	5.82e-05	200	47	4	abf4ba5fcb54cdeada0da1a8b956a30aa47679e4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.82e-05	200	47	4	50fa0f8a3e490d5941b34e66a10158eba6c909d4
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	HMBOX1 BMPR2 SETX ERG	5.82e-05	200	47	4	432384faeade8e609154fab3d96c955a8ec868dd
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.82e-05	200	47	4	b1be27d134a8633e3e7862c6a0d7be2001d387f0
ToppCell	kidney_cells-Adult_normal_reference-Endothelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.82e-05	200	47	4	9f1626a7e1bd00977a5c316cafbdf654b52bad94
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control_saline / Treatment groups by lineage, cell group, cell type	BMPR2 SETX ERG PTTG1IP	5.82e-05	200	47	4	041a34080120c9f613373c20dcc366292f558040
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HMBOX1 BMPR2 SETX ERG	5.82e-05	200	47	4	89821a264e872ed53e08e9d3609d5cc5c314503e
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HSPG2 BMPR2 PLXND1 ERG	5.82e-05	200	47	4	ced14d83222dbebca85c40540e76824e683354f3
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	BMPR2 TTYH3 SETX ERG	5.82e-05	200	47	4	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
ToppCell	Sepsis-Bac-SEP-Lymphocyte-T/NK-NK_CD56bright\|Bac-SEP / Disease, condition lineage and cell class	KMT2A SCLY CCDC66 DMKN	5.82e-05	200	47	4	ebab762fe5209c23c5a9ac9281f728fafa433af3
Computational	Genes upregulated in subsets of cells of a given type within various tumors	KMT2A GPRIN3 SETX	2.41e-04	49	27	3	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Disease	congenital heart disease (implicated_via_orthology)	LRP2 KMT2A USP42	1.62e-04	69	45	3	DOID:1682 (implicated_via_orthology)
Disease	Amyotrophic lateral sclerosis	SETX UBQLN2	3.05e-04	17	45	2	cv:C0002736
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 COMP	3.83e-04	19	45	2	DOID:2256 (is_implicated_in)
Disease	unipolar depression, depressive symptom measurement	KMT2A MAML3	7.22e-04	26	45	2	EFO_0003761, EFO_0007006
Disease	inflammatory biomarker measurement	PIEZO2 F5	7.22e-04	26	45	2	EFO_0004872
Disease	pulmonary hypertension (is_implicated_in)	BMPR2 F5	9.63e-04	30	45	2	DOID:6432 (is_implicated_in)
Disease	hypertension (implicated_via_orthology)	ADAMTS16 LRP2 DRD3	9.90e-04	128	45	3	DOID:10763 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
RNQADNCPRVPNSDQ	COMP	381	P49747
NPSQVNGSRNSPDEC	ERG	71	P11308
GPQENSVQSSACGRQ	ADAMTS13	1181	Q76LX8
PQPAPSSRQACNSQS	ADAMTS16	971	Q8TE57
SDQQAGPCVNRGTQT	ANKRD6	606	Q9Y2G4
VTCSNSHNPSNSNQP	NBPF4	211	Q96M43
NSGNQPTPCRVAALQ	RCBTB2	241	O95199
NPSQGQPCQRDSQVP	HSPG2	1256	P98160
VSNPNENSLNSNPVC	KIAA1107	581	Q9UPP5
ANCAVQSPQTPNQAH	MAML3	411	Q96JK9
DTSPQPCTTNQNGRE	HMBOX1	106	Q6NT76
NQSRCEASPNPTSPQ	PLXND1	736	Q9Y4D7
QQRQPNATNPCGIDN	LRP6	276	O75581
CNQNSSNPNQRHPIT	LAMA2	86	P24043
NIQTGSNACNQPTHP	LRP2	966	P98164
ASEQSPSPQSPQNNC	MLXIP	691	Q9HAP2
QLQQSNSCPAPQQAA	ERVK-5	651	Q9HDB9
QRNSSCGPPHQRADQ	IGSF5	366	Q9NSI5
RASNQNEGCTNPPPS	DMKN	221	Q6E0U4
DSQNPPTVNNCAQDR	FNBP1	501	Q96RU3
EGGRTNSNNNNSNPC	BMPR2	896	Q13873
GPSTQDPQYQNSQDC	CCDC66	866	A2RUB6
SFGSAAQQQQPPCEQ	CEP192	1011	Q8TEP8
AQPSPNNTSCQDSQS	KMT2A	2571	Q03164
TQNEPSQNCHPANLE	CEP57L1	26	Q8IYX8
NQHTCQSIPGDQPNA	GPRIN3	131	Q6ZVF9
RQNSQCNSVRPGFPQ	DRD3	226	P35462
RNNAASARNNPGSVP	RNF207	571	Q6ZRF8
PGNHTQSRPCQENST	SSPOP	3511	A2VEC9
NQNSSNDTGQASCPP	F5	1101	P12259
VTCSNSHNPSNSNQP	NBPF5P	211	Q86XG9
VTCSNSHNPSNSNQP	NBPF6	211	Q5VWK0
PSPNNQQATNTCDGR	TBX15	571	Q96SF7
CNVLHPQSPNNSNRQ	SETX	1656	Q7Z333
LANNNRAPVTCTPGQ	MTG2	196	Q9H4K7
NQLDSPQTGQCPDQA	ST18	451	O60284
NSQFPGTQRLPNTCN	SCLY	346	Q96I15
PVRQCQSQPNLHSNS	USP42	531	Q9H9J4
THQPQAQQNEPSECR	PAPLN	706	O95428
SVNCSLPNENQTNIP	PIEZO2	1011	Q9H5I5
APPSGQQALQCNRNK	TXLNGY	76	Q9BZA5
AAQEPPGAACSQNTN	PTTG1IP	31	P53801
QCQPNSDTSLSGNNV	ZNF507	616	Q8TCN5
LPQGANANQDSSNRP	ZSWIM6	496	Q9HCJ5
NRPQGQSTQPSNAAG	UBQLN2	106	Q9UHD9
SNICPSNLNQSNGTG	UBR4	2446	Q5T4S7
SQNANFQNPRCENTP	TTYH3	476	Q9C0H2
QSVCDPPSQNNAANI	ZMYM4	851	Q5VZL5
QIPAEQQENPSGNCR	ZAN	2116	Q9Y493