Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	sodium ion binding	SCN1A SCN2A SCN8A	8.71e-06	14	59	3	GO:0031402
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN1A SCN2A SCN8A	6.07e-05	26	59	3	GO:0005248
GeneOntologyMolecularFunction	alkali metal ion binding	SCN1A SCN2A SCN8A	6.07e-05	26	59	3	GO:0031420
GeneOntologyMolecularFunction	metallocarboxypeptidase activity	CPA6 CPA1 CPB1	1.04e-04	31	59	3	GO:0004181
GeneOntologyMolecularFunction	trace-amine receptor activity	TAAR9 TAAR6	2.38e-04	8	59	2	GO:0001594
GeneOntologyMolecularFunction	exopeptidase activity	GGH CPA6 CPA1 CPB1	3.14e-04	110	59	4	GO:0008238
GeneOntologyMolecularFunction	complement component C1q complex binding	C4A C4B	3.80e-04	10	59	2	GO:0001849
GeneOntologyMolecularFunction	hexosyltransferase activity	DPY19L3 HYAL1 DPY19L4 EXTL3 GCNT1	3.96e-04	211	59	5	GO:0016758
GeneOntologyMolecularFunction	carboxypeptidase activity	CPA6 CPA1 CPB1	4.10e-04	49	59	3	GO:0004180
GeneOntologyMolecularFunction	sodium channel activity	SCN1A SCN2A SCN8A	4.89e-04	52	59	3	GO:0005272
GeneOntologyMolecularFunction	voltage-gated monoatomic ion channel activity involved in regulation of presynaptic membrane potential	SCN1A SCN2A	1.13e-03	17	59	2	GO:0099508
GeneOntologyMolecularFunction	metalloexopeptidase activity	CPA6 CPA1 CPB1	1.17e-03	70	59	3	GO:0008235
GeneOntologyMolecularFunction	glycosyltransferase activity	DPY19L3 HYAL1 DPY19L4 EXTL3 GCNT1	1.60e-03	288	59	5	GO:0016757
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SCN1A SCN2A SCN8A SLC6A15	1.64e-03	171	59	4	GO:0015081
GeneOntologyMolecularFunction	opsonin binding	C4A C4B	2.46e-03	25	59	2	GO:0001846
GeneOntologyMolecularFunction	mannosyltransferase activity	DPY19L3 DPY19L4	3.09e-03	28	59	2	GO:0000030
GeneOntologyBiologicalProcess	protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan	DPY19L3 DPY19L4	1.20e-04	6	59	2	GO:0018406
GeneOntologyBiologicalProcess	peptidyl-tryptophan modification	DPY19L3 DPY19L4	1.20e-04	6	59	2	GO:0018211
GeneOntologyBiologicalProcess	protein C-linked glycosylation	DPY19L3 DPY19L4	1.20e-04	6	59	2	GO:0018103
GeneOntologyBiologicalProcess	protein C-linked glycosylation via tryptophan	DPY19L3 DPY19L4	1.20e-04	6	59	2	GO:0018317
GeneOntologyBiologicalProcess	membrane depolarization during action potential	SCN1A SCN2A SCN8A	1.48e-04	36	59	3	GO:0086010
GeneOntologyBiologicalProcess	positive regulation of apoptotic cell clearance	C4A C4B	2.23e-04	8	59	2	GO:2000427
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN1A SCN2A SCN8A	1.41e-05	17	59	3	GO:0001518
GeneOntologyCellularComponent	node of Ranvier	SCN1A SCN2A SCN8A	2.35e-05	20	59	3	GO:0033268
GeneOntologyCellularComponent	axon initial segment	SCN1A SCN2A SCN8A	7.41e-05	29	59	3	GO:0043194
GeneOntologyCellularComponent	sodium channel complex	SCN1A SCN2A SCN8A	7.41e-05	29	59	3	GO:0034706
GeneOntologyCellularComponent	symbiont cell surface	C4A C4B	2.17e-04	8	59	2	GO:0106139
GeneOntologyCellularComponent	other organism part	C4A C4B	2.78e-04	9	59	2	GO:0044217
GeneOntologyCellularComponent	nuclear outer membrane-endoplasmic reticulum membrane network	CLPTM1L GJB1 TRAF2 DPY19L3 SEC22C FAF2 CYP7A1 ATP10B EXTL3 RAB14 REEP3	1.08e-03	1327	59	11	GO:0042175
GeneOntologyCellularComponent	ciliary transition zone	NEK4 TMEM17 USH2A	1.56e-03	81	59	3	GO:0035869
HumanPheno	Abnormality of salivation	POLR3B PCGF2 SCN1A SCN2A C4A C4B EXTL3	7.07e-06	215	19	7	HP:0100755
HumanPheno	Focal automatism seizure	SCN1A SCN2A SCN8A	9.48e-06	12	19	3	HP:0032898
HumanPheno	Complex febrile seizure	SCN1A SCN2A SCN8A	2.39e-05	16	19	3	HP:0011172
HumanPheno	Visually-induced seizure	CPA6 SCN1A SCN2A	3.47e-05	18	19	3	HP:0020216
HumanPheno	Reflex seizure	CPA6 SCN1A SCN2A	6.48e-05	22	19	3	HP:0020207
HumanPheno	Focal hemiclonic seizure	SCN1A SCN2A SCN8A	9.61e-05	25	19	3	HP:0006813
HumanPheno	Simple febrile seizure	SCN1A SCN2A SCN8A	1.22e-04	27	19	3	HP:0011171
HumanPheno	Neonatal electro-clinical non-motor seizure	SCN2A SCN8A	1.31e-04	5	19	2	HP:0032812
HumanPheno	Neonatal seizure with electrographic correlate	SCN2A SCN8A	1.31e-04	5	19	2	HP:0032808
HumanPheno	Neonatal electro-clinical seizure	SCN2A SCN8A	1.31e-04	5	19	2	HP:0032809
HumanPheno	Neonatal electro-clinical seizure with behavior arrest	SCN2A SCN8A	1.31e-04	5	19	2	HP:0032823
HumanPheno	Focal head nodding automatism seizure	SCN2A SCN8A	1.31e-04	5	19	2	HP:0032906
HumanPheno	Focal aware seizure	CPA6 SCN1A SCN2A	1.36e-04	28	19	3	HP:0002349
HumanPheno	Progressive gait ataxia	GJB1 SCN1A SCN2A	1.68e-04	30	19	3	HP:0007240
HumanPheno	Progressive ataxia	GJB1 SCN1A SCN2A	1.68e-04	30	19	3	HP:0001329
HumanPheno	Abnormal oral physiology	POLR3B PCGF2 SCN1A SCN2A C4A C4B EXTL3	1.82e-04	355	19	7	HP:0031815
HumanPheno	Normal interictal EEG	SCN2A SCN8A	1.96e-04	6	19	2	HP:0002372
HumanPheno	Drooling	POLR3B PCGF2 SCN1A SCN2A EXTL3	2.41e-04	161	19	5	HP:0002307
HumanPheno	Generalized clonic seizure	SCN1A SCN2A SCN8A	2.45e-04	34	19	3	HP:0011169
HumanPheno	EEG with spike-wave complexes	CPA6 SCN1A SCN2A SCN8A	2.64e-04	88	19	4	HP:0010850
HumanPheno	Eyelid myoclonia seizure	SCN2A SCN8A	2.74e-04	7	19	2	HP:0032678
HumanPheno	Excessive salivation	POLR3B PCGF2 SCN1A SCN2A EXTL3	3.10e-04	170	19	5	HP:0003781
HumanPheno	Photosensitive myoclonic seizure	SCN1A SCN2A	3.64e-04	8	19	2	HP:0001327
HumanPheno	Cyanotic episode	SCN1A SCN2A	3.64e-04	8	19	2	HP:0200048
HumanPheno	Focal non-motor seizure	SCN1A SCN2A SCN8A	3.98e-04	40	19	3	HP:0032679
HumanPheno	Focal clonic seizure	SCN1A SCN2A SCN8A	4.61e-04	42	19	3	HP:0002266
HumanPheno	Sudden unexpected death in epilepsy	SCN1A SCN8A	5.83e-04	10	19	2	HP:0033258
HumanPheno	Dermatological manifestations of systemic disorders	TRHR SCN1A SCN2A SCN8A CPA1 C4A C4B	6.41e-04	435	19	7	HP:0001005
HumanPheno	Abnormal hippocampus morphology	CPA6 SCN1A SCN2A	6.85e-04	48	19	3	HP:0025100
HumanPheno	Neonatal seizure	SCN2A SCN8A	7.11e-04	11	19	2	HP:0032807
HumanPheno	Limited neck range of motion	SCN1A SCN2A	7.11e-04	11	19	2	HP:0000466
HumanPheno	Cervical spinal canal stenosis	IARS2 EXTL3	7.11e-04	11	19	2	HP:0008445
HumanPheno	Abnormal morphology of the limbic system	CPA6 SCN1A SCN2A	7.27e-04	49	19	3	HP:0007343
HumanPheno	Epilepsia partialis continua	SCN1A SCN2A	8.51e-04	12	19	2	HP:0012847
HumanPheno	Bilateral tonic-clonic seizure with focal onset	SCN1A SCN2A SCN8A	8.66e-04	52	19	3	HP:0007334
HumanPheno	Generalized cerebral atrophy/hypoplasia	SCN1A SCN2A	1.00e-03	13	19	2	HP:0007058
HumanPheno	Gaze-evoked nystagmus	POLR3B SCN1A SCN8A	1.02e-03	55	19	3	HP:0000640
HumanPheno	Focal impaired awareness seizure	CPA6 SCN1A SCN2A SCN8A	1.04e-03	126	19	4	HP:0002384
Domain	Na_trans_cytopl	SCN1A SCN2A SCN8A	5.95e-07	6	59	3	PF11933
Domain	Na_trans_cytopl	SCN1A SCN2A SCN8A	5.95e-07	6	59	3	IPR024583
Domain	-	CPA6 CPA1 CPB1	1.66e-06	8	59	3	3.30.70.340
Domain	Propep_M14	CPA6 CPA1 CPB1	1.66e-06	8	59	3	PF02244
Domain	M14A_act_pep	CPA6 CPA1 CPB1	1.66e-06	8	59	3	IPR003146
Domain	Na_channel_asu	SCN1A SCN2A SCN8A	3.54e-06	10	59	3	IPR001696
Domain	Na_trans_assoc	SCN1A SCN2A SCN8A	3.54e-06	10	59	3	IPR010526
Domain	Na_trans_assoc	SCN1A SCN2A SCN8A	3.54e-06	10	59	3	PF06512
Domain	Propept_inh	CPA6 CPA1 CPB1	1.97e-05	17	59	3	IPR009020
Domain	Zn_pept	CPA6 CPA1 CPB1	2.36e-05	18	59	3	SM00631
Domain	CARBOXYPEPT_ZN_2	CPA6 CPA1 CPB1	2.80e-05	19	59	3	PS00133
Domain	REKLES_domain	ARID3A ARID3C	2.94e-05	3	59	2	IPR023334
Domain	REKLES	ARID3A ARID3C	2.94e-05	3	59	2	PS51486
Domain	CARBOXYPEPT_ZN_1	CPA6 CPA1 CPB1	3.29e-05	20	59	3	PS00132
Domain	Peptidase_M14	CPA6 CPA1 CPB1	5.07e-05	23	59	3	PF00246
Domain	Peptidase_M14	CPA6 CPA1 CPB1	5.07e-05	23	59	3	IPR000834
Domain	Dpy19	DPY19L3 DPY19L4	5.86e-05	4	59	2	PF10034
Domain	Dpy-19/Dpy-19-like	DPY19L3 DPY19L4	5.86e-05	4	59	2	IPR018732
Domain	Anaphylatoxin_comp_syst	C4A C4B	9.75e-05	5	59	2	IPR018081
Domain	Anaphylatoxn_comp_syst_dom	C4A C4B	9.75e-05	5	59	2	IPR001840
Domain	ANATO	C4A C4B	2.04e-04	7	59	2	SM00104
Domain	ANATO	C4A C4B	2.04e-04	7	59	2	PF01821
Domain	TAAR_fam	TAAR9 TAAR6	2.04e-04	7	59	2	IPR009132
Domain	ANAPHYLATOXIN_2	C4A C4B	2.04e-04	7	59	2	PS01178
Domain	ANAPHYLATOXIN_1	C4A C4B	2.04e-04	7	59	2	PS01177
Domain	Anaphylatoxin/fibulin	C4A C4B	2.04e-04	7	59	2	IPR000020
Domain	Thiol-ester_cl	C4A C4B	2.71e-04	8	59	2	PF10569
Domain	MacrogloblnA2_thiol-ester-bond	C4A C4B	2.71e-04	8	59	2	IPR019565
Domain	MacrogloblnA2_CS	C4A C4B	2.71e-04	8	59	2	IPR019742
Domain	A2M_N	C4A C4B	4.34e-04	10	59	2	PF01835
Domain	A2M_N	C4A C4B	4.34e-04	10	59	2	IPR002890
Domain	A-macroglobulin_rcpt-bd	C4A C4B	4.34e-04	10	59	2	IPR009048
Domain	ALPHA_2_MACROGLOBULIN	C4A C4B	4.34e-04	10	59	2	PS00477
Domain	A2M	C4A C4B	4.34e-04	10	59	2	PF00207
Domain	A2M_N_2	C4A C4B	4.34e-04	10	59	2	IPR011625
Domain	A2M_comp	C4A C4B	4.34e-04	10	59	2	IPR011626
Domain	A2M_N_2	C4A C4B	4.34e-04	10	59	2	PF07703
Domain	A2M_recep	C4A C4B	4.34e-04	10	59	2	PF07677
Domain	A2M_comp	C4A C4B	4.34e-04	10	59	2	PF07678
Domain	Macroglobln_a2	C4A C4B	4.34e-04	10	59	2	IPR001599
Domain	Ion_trans_dom	SCN1A SCN2A TRPC5 SCN8A	4.63e-04	114	59	4	IPR005821
Domain	Ion_trans	SCN1A SCN2A TRPC5 SCN8A	4.63e-04	114	59	4	PF00520
Domain	Channel_four-helix_dom	SCN1A SCN2A SCN8A	7.76e-04	57	59	3	IPR027359
Domain	-	SCN1A SCN2A SCN8A	7.76e-04	57	59	3	1.20.120.350
Domain	-	ARID3A ARID3C	1.00e-03	15	59	2	1.10.150.60
Domain	BRIGHT	ARID3A ARID3C	1.00e-03	15	59	2	SM00501
Domain	ARID_dom	ARID3A ARID3C	1.00e-03	15	59	2	IPR001606
Domain	ARID	ARID3A ARID3C	1.00e-03	15	59	2	PS51011
Domain	ARID	ARID3A ARID3C	1.00e-03	15	59	2	PF01388
Domain	C345C	C4A C4B	1.29e-03	17	59	2	SM00643
Domain	Terpenoid_cyclase/PrenylTrfase	C4A C4B	1.45e-03	18	59	2	IPR008930
Domain	NTR	C4A C4B	1.62e-03	19	59	2	PF01759
Domain	Netrin_module_non-TIMP	C4A C4B	1.62e-03	19	59	2	IPR018933
Domain	IQ	SCN1A SCN2A SCN8A	2.14e-03	81	59	3	SM00015
Domain	NTR	C4A C4B	2.38e-03	23	59	2	PS50189
Domain	Netrin_domain	C4A C4B	2.38e-03	23	59	2	IPR001134
Domain	IQ_motif_EF-hand-BS	SCN1A SCN2A SCN8A	2.89e-03	90	59	3	IPR000048
Domain	TIMP-like_OB-fold	C4A C4B	3.04e-03	26	59	2	IPR008993
Domain	IQ	SCN1A SCN2A SCN8A	3.18e-03	93	59	3	PS50096
Domain	7TM_GPCR_Srsx	TRHR TAAR9 TAAR6	5.35e-03	112	59	3	SM01381
Pathway	WP_DRAVET_SYNDROME	SCN1A SCN2A SCN8A	7.11e-05	28	41	3	M45519
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SCN1A SCN2A SCN8A	9.70e-05	31	41	3	M877
Pathway	REACTOME_PHASE_0_RAPID_DEPOLARISATION	SCN1A SCN2A SCN8A	1.07e-04	32	41	3	M27455
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	1.72e-04	7	41	2	MM14685
Pathway	REACTOME_ACTIVATION_OF_C3_AND_C5	C4A C4B	2.29e-04	8	41	2	M27031
Pathway	KEGG_MEDICUS_REFERENCE_CLASSICAL_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	2.29e-04	8	41	2	M47872
Pathway	WP_OXIDATIVE_DAMAGE_RESPONSE	TRAF2 C4A C4B	2.42e-04	42	41	3	MM15945
Pathway	WP_RETT_SYNDROME	SCN1A SCN2A SCN8A	3.61e-04	48	41	3	M39759
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	4.46e-04	11	41	2	MM1430
Pathway	REACTOME_REGULATION_BY_C_FLIP	TRAF2 TNFSF10	4.46e-04	11	41	2	M27249
Pathway	KEGG_MEDICUS_REFERENCE_LECTIN_PATHWAY_OF_COMPLEMENT_CASCADE_C4_C2_TO_C3_CONVERTASE_FORMATION	C4A C4B	4.46e-04	11	41	2	M47874
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	5.35e-04	12	41	2	MM1368
Pathway	REACTOME_REGULATION_BY_C_FLIP	TRAF2 TNFSF10	6.31e-04	13	41	2	MM14947
Pathway	BIOCARTA_LECTIN_PATHWAY	C4A C4B	6.31e-04	13	41	2	M4732
Pathway	BIOCARTA_CLASSIC_PATHWAY	C4A C4B	8.46e-04	15	41	2	M7146
Pathway	REACTOME_CASPASE_ACTIVATION_VIA_DEATH_RECEPTORS_IN_THE_PRESENCE_OF_LIGAND	TRAF2 TNFSF10	9.65e-04	16	41	2	M26947
Pathway	WP_COMPLEMENT_ACTIVATION_CLASSICAL_PATHWAY	C4A C4B	1.09e-03	17	41	2	MM15944
Pathway	BIOCARTA_COMP_PATHWAY	C4A C4B	1.09e-03	17	41	2	MM1369
Pathway	REACTOME_CASPASE_ACTIVATION_VIA_DEATH_RECEPTORS_IN_THE_PRESENCE_OF_LIGAND	TRAF2 TNFSF10	1.37e-03	19	41	2	MM14555
Pubmed	Variable patterns of mutation density among NaV1.1, NaV1.2 and NaV1.6 point to channel-specific functional differences associated with childhood epilepsy.	SCN1A SCN2A SCN8A	4.64e-09	3	59	3	32845893
Pubmed	Comparison and optimization of in silico algorithms for predicting the pathogenicity of sodium channel variants in epilepsy.	SCN1A SCN2A SCN8A	4.64e-09	3	59	3	28518218
Pubmed	Reduced sodium current in Purkinje neurons from Nav1.1 mutant mice: implications for ataxia in severe myoclonic epilepsy in infancy.	SCN1A SCN2A SCN8A	4.64e-09	3	59	3	17928448
Pubmed	Nav1.1 localizes to axons of parvalbumin-positive inhibitory interneurons: a circuit basis for epileptic seizures in mice carrying an Scn1a gene mutation.	SCN1A SCN2A SCN8A	1.85e-08	4	59	3	17537961
Pubmed	Sodium channel expression and transcript variation in the developing brain of human, Rhesus monkey, and mouse.	SCN1A SCN2A SCN8A	1.85e-08	4	59	3	35031483
Pubmed	Abnormal changes in voltage-gated sodium channels subtypes NaV1.1, NaV1.2, NaV1.3, NaV1.6 and CaM/CaMKII pathway in low-grade astrocytoma.	SCN1A SCN2A SCN8A	1.85e-08	4	59	3	29578003
Pubmed	Neuronal voltage-gated ion channels are genetic modifiers of generalized epilepsy with febrile seizures plus.	SCN1A SCN2A SCN8A	1.85e-08	4	59	3	21156207
Pubmed	A 'toothache tree' alkylamide inhibits Aδ mechanonociceptors to alleviate mechanical pain.	SCN1A SCN2A SCN8A	9.24e-08	6	59	3	23652591
Pubmed	Diagnostic yield of genetic testing in epileptic encephalopathy in childhood.	SCN1A SCN2A SCN8A	1.62e-07	7	59	3	25818041
Pubmed	International Union of Pharmacology. XLVII. Nomenclature and structure-function relationships of voltage-gated sodium channels.	SCN1A SCN2A SCN8A	3.87e-07	9	59	3	16382098
Pubmed	Expression pattern of neuronal and skeletal muscle voltage-gated Na+ channels in the developing mouse heart.	SCN1A SCN2A SCN8A	3.87e-07	9	59	3	15746173
Pubmed	Nav1.2 haplodeficiency in excitatory neurons causes absence-like seizures in mice.	SCN1A SCN2A SCN8A	1.01e-06	12	59	3	30175250
Pubmed	Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.	SCN1A SCN2A SCN8A	1.31e-06	13	59	3	15123669
Pubmed	Copy number analysis of complement C4A, C4B and C4A silencing mutation by real-time quantitative polymerase chain reaction.	C4A C4B	2.83e-06	2	59	2	22737222
Pubmed	Deficiency of C4 from donor or recipient mouse fails to prevent renal allograft rejection.	C4A C4B	2.83e-06	2	59	2	16565498
Pubmed	Complete deficiencies of complement C4A and C4B including 2-bp insertion in codon 1213 are genetic risk factors of systemic lupus erythematosus in Thai populations.	C4A C4B	2.83e-06	2	59	2	15998580
Pubmed	Association between SCN1A and SCN2A mutations and clinical/EEG features in Chinese patients from epilepsy or severe seizures.	SCN1A SCN2A	2.83e-06	2	59	2	29649454
Pubmed	Structural polymorphism of murine C4 and its linkage to H-2.	C4A C4B	2.83e-06	2	59	2	7373044
Pubmed	High-throughput analysis of the C4 polymorphism by a combination of MLPA and isotype-specific ELISA's.	C4A C4B	2.83e-06	2	59	2	19062096
Pubmed	The chemical structure of the C4d fragment of the human complement component C4.	C4A C4B	2.83e-06	2	59	2	3696167
Pubmed	Restriction fragment length polymorphism of the murine C4 and Slp genes: two C4 groups.	C4A C4B	2.83e-06	2	59	2	1357031
Pubmed	Reduction of Kcnt1 is therapeutic in mouse models of SCN1A and SCN8A epilepsy.	SCN1A SCN8A	2.83e-06	2	59	2	37901435
Pubmed	Structural comparison of human C4A3 and C4B1 after proteolytic activation by C1s.	C4A C4B	2.83e-06	2	59	2	16098595
Pubmed	Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice.	C4A C4B	2.83e-06	2	59	2	19933335
Pubmed	Structural basis for the C4d.1/C4d.2 serologic allotypes of murine complement component C4.	C4A C4B	2.83e-06	2	59	2	2459207
Pubmed	Antigen-induced B cell apoptosis is independent of complement C4.	C4A C4B	2.83e-06	2	59	2	17645767
Pubmed	An Scn1a epilepsy mutation in Scn8a alters seizure susceptibility and behavior.	SCN1A SCN8A	2.83e-06	2	59	2	26410685
Pubmed	Increased frequency of C4B*Q0 alleles in patients with Henoch-Schönlein purpura.	C4A C4B	2.83e-06	2	59	2	15787745
Pubmed	Anti-DNA autoreactivity in C4-deficient mice.	C4A C4B	2.83e-06	2	59	2	12207352
Pubmed	Neuronal death and perinatal lethality in voltage-gated sodium channel alpha(II)-deficient mice.	SCN1A SCN2A	2.83e-06	2	59	2	10827969
Pubmed	Neuropil contraction in relation to Complement C4 gene copy numbers in independent cohorts of adolescent-onset and young adult-onset schizophrenia patients-a pilot study.	C4A C4B	2.83e-06	2	59	2	30026462
Pubmed	A molecular map of the human major histocompatibility complex class III region linking complement genes C4, C2 and factor B.	C4A C4B	2.83e-06	2	59	2	6559257
Pubmed	Endoplasmic stress-inducing variants in CPB1 and CPA1 and risk of pancreatic cancer: A case-control study and meta-analysis.	CPA1 CPB1	2.83e-06	2	59	2	34817877
Pubmed	Complement C4A and C4B Gene Copy Number Study in Alzheimer's Disease Patients.	C4A C4B	2.83e-06	2	59	2	27758680
Pubmed	Genetically determined partial complement C4 deficiency states are not independent risk factors for SLE in UK and Spanish populations.	C4A C4B	2.83e-06	2	59	2	22387014
Pubmed	Complement C4 Is Reduced in iPSC-Derived Astrocytes of Autism Spectrum Disorder Subjects.	C4A C4B	2.83e-06	2	59	2	34299197
Pubmed	Assessment of complement C4 gene copy number using the paralog ratio test.	C4A C4B	2.83e-06	2	59	2	20506482
Pubmed	Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population.	SCN1A SCN2A	2.83e-06	2	59	2	19694741
Pubmed	Commonalities and distinctions between two neurodevelopmental disorder subtypes associated with SCN2A and SCN8A variants and literature review.	SCN2A SCN8A	2.83e-06	2	59	2	35348308
Pubmed	Polymerase chain reaction based C4AQ0 and C4BQ0 genotyping: association with systemic lupus erythematosus in southwest Han Chinese.	C4A C4B	2.83e-06	2	59	2	12480675
Pubmed	Low C4, C4A and C4B gene copy numbers are stronger risk factors for juvenile-onset than for adult-onset systemic lupus erythematosus.	C4A C4B	2.83e-06	2	59	2	26800705
Pubmed	Complement C4 maintains peripheral B-cell tolerance in a myeloid cell dependent manner.	C4A C4B	2.83e-06	2	59	2	23749435
Pubmed	Copy number variations of complement component C4 are associated with Behçet's disease but not with ankylosing spondylitis associated with acute anterior uveitis.	C4A C4B	2.83e-06	2	59	2	23918728
Pubmed	Electrophysiological properties of two axonal sodium channels, Nav1.2 and Nav1.6, expressed in mouse spinal sensory neurones.	SCN2A SCN8A	2.83e-06	2	59	2	15760941
Pubmed	Murine complement C4 is not required for experimental autoimmune encephalomyelitis.	C4A C4B	2.83e-06	2	59	2	15390104
Pubmed	Molecular genetics of androgen-dependent and -independent expression of mouse sex-limited protein.	C4A C4B	2.83e-06	2	59	2	3037333
Pubmed	Evidence of a role for C4 in modulating interstitial inflammation in experimental glomerulonephritis.	C4A C4B	2.83e-06	2	59	2	11726230
Pubmed	Quantitative variations in the expression of the mouse serum antigen Ss and its sex-limited allotype Slp.	C4A C4B	2.83e-06	2	59	2	4216347
Pubmed	Importance of the alpha 3-fragment of complement C4 for the binding with C4b-binding protein.	C4A C4B	2.83e-06	2	59	2	1699796
Pubmed	Sequence determination of the thiolester site of the fourth component of human complement.	C4A C4B	2.83e-06	2	59	2	6950384
Pubmed	Molecular cloning and characterization of complementary and genomic DNA clones for mouse C4 and Slp.	C4A C4B	2.83e-06	2	59	2	2997024
Pubmed	Differential expression of two sodium channel subtypes in human brain.	SCN1A SCN2A	2.83e-06	2	59	2	1317301
Pubmed	Visual demonstration of the organization of the human complement C4 and 21-hydroxylase genes by high-resolution fluorescence in situ hybridization.	C4A C4B	2.83e-06	2	59	2	8660986
Pubmed	Constitutive expression of Slp genes in mouse strain B10.WR directed by C4 regulatory sequences.	C4A C4B	2.83e-06	2	59	2	3624865
Pubmed	Tissue-specific RNA processing for the complement C4 gene transcript in the H-2k mouse strain.	C4A C4B	2.83e-06	2	59	2	8428773
Pubmed	Determination of the loss of function complement C4 exon 29 CT insertion using a novel paralog-specific assay in healthy UK and Spanish populations.	C4A C4B	2.83e-06	2	59	2	21857912
Pubmed	Complement C4 deficiency--a plausible risk factor for non-tuberculous mycobacteria (NTM) infection in apparently immunocompetent patients.	C4A C4B	2.83e-06	2	59	2	24638111
Pubmed	Isolation of cDNA clones specifying the fourth component of mouse complement and its isotype, sex-limited protein.	C4A C4B	2.83e-06	2	59	2	6208559
Pubmed	The role of the histocompatibility-2-linked Ss-Slp region in the control of mouse complement.	C4A C4B	2.83e-06	2	59	2	4514997
Pubmed	Transcriptional repression of C4 complement by hepatitis C virus proteins.	C4A C4B	2.83e-06	2	59	2	21345967
Pubmed	Effects of SCN1A and SCN2A polymorphisms on responsiveness to valproic acid monotherapy in epileptic children.	SCN1A SCN2A	2.83e-06	2	59	2	33096315
Pubmed	The inheritance of susceptibility to the Gross leukemia virus in mice.	C4A C4B	2.83e-06	2	59	2	5919331
Pubmed	An ancient provirus has imposed androgen regulation on the adjacent mouse sex-limited protein gene.	C4A C4B	2.83e-06	2	59	2	3167981
Pubmed	Clinical exome sequencing identifies two novel mutations of the SCN1A and SCN2A genes in Moroccan patients with epilepsy: a case series.	SCN1A SCN2A	2.83e-06	2	59	2	31439038
Pubmed	The dichotomous size variation of human complement C4 genes is mediated by a novel family of endogenous retroviruses, which also establishes species-specific genomic patterns among Old World primates.	C4A C4B	2.83e-06	2	59	2	7545960
Pubmed	Insights on the relationship between complement component C4 serum concentrations and C4 gene copy numbers in a Western Australian systemic lupus erythematosus cohort.	C4A C4B	2.83e-06	2	59	2	30041577
Pubmed	Restriction fragment analysis of H-2 recombinant mouse strains with crossovers between E alpha and C4 genes.	C4A C4B	2.83e-06	2	59	2	2572548
Pubmed	The complement component C4 of mammals.	C4A C4B	2.83e-06	2	59	2	2302180
Pubmed	Complete cDNA sequence of the fourth component of murine complement.	C4A C4B	2.83e-06	2	59	2	3862104
Pubmed	The BS variant of C4 protects against age-related loss of white matter microstructural integrity.	C4A C4B	2.83e-06	2	59	2	34358307
Pubmed	Acute renal allograft rejection: diagnostic significance of focal peritubular capillary C4d.	C4A C4B	2.83e-06	2	59	2	18360261
Pubmed	Gene CNVs and protein levels of complement C4A and C4B as novel biomarkers for partial disease remissions in new-onset type 1 diabetes patients.	C4A C4B	2.83e-06	2	59	2	22151770
Pubmed	C4d-positive chronic rejection: a frequent entity with a poor outcome.	C4A C4B	2.83e-06	2	59	2	18091514
Pubmed	Comprehensive approach to study complement C4 in systemic lupus erythematosus: Gene polymorphisms, protein levels and functional activity.	C4A C4B	2.83e-06	2	59	2	29080553
Pubmed	Schizophrenia risk from complex variation of complement component 4.	C4A C4B	2.83e-06	2	59	2	26814963
Pubmed	Genes for murine fourth complement component (C4) and sex-limited protein (Slp) identified by hybridization to C4- and Slp-specific cDNA.	C4A C4B	2.83e-06	2	59	2	6589636
Pubmed	C4 Deficiency is a predisposing factor for Streptococcus pneumoniae-induced autoantibody production.	C4A C4B	2.83e-06	2	59	2	25339671
Pubmed	A study of association of the complement C4 mutations with systemic lupus erythematosus in the Malaysian population.	C4A C4B	2.83e-06	2	59	2	17728371
Pubmed	Sodium channel expression within chronic multiple sclerosis plaques.	SCN2A SCN8A	2.83e-06	2	59	2	17805013
Pubmed	Structure and organization of the C4 genes.	C4A C4B	2.83e-06	2	59	2	6149580
Pubmed	Sequence heterogeneity of murine complementary DNA clones related to the C4 and C4-Slp isoforms of the fourth complement component.	C4A C4B	2.83e-06	2	59	2	6149581
Pubmed	Missense mutations in sodium channel SCN1A and SCN2A predispose children to encephalopathy with severe febrile seizures.	SCN1A SCN2A	2.83e-06	2	59	2	26311622
Pubmed	Aberrant regulation of a poison exon caused by a non-coding variant in a mouse model of Scn1a-associated epileptic encephalopathy.	SCN1A SCN8A	2.83e-06	2	59	2	33411788
Pubmed	The follicular dendritic cell restricted epitope, FDC-M2, is complement C4; localization of immune complexes in mouse tissues.	C4A C4B	2.83e-06	2	59	2	12115608
Pubmed	Biochemistry and biology of anaphylatoxins.	C4A C4B	2.83e-06	2	59	2	3542363
Pubmed	C4 from C4-high and C4-low mouse strains have identical sequences in the region corresponding to the isotype-specific segment of human C4.	C4A C4B	2.83e-06	2	59	2	2387317
Pubmed	Promoter elements of the mouse complement C4 gene critical for transcription activation and start site location.	C4A C4B	2.83e-06	2	59	2	8132550
Pubmed	Scn8a Antisense Oligonucleotide Is Protective in Mouse Models of SCN8A Encephalopathy and Dravet Syndrome.	SCN1A SCN8A	2.83e-06	2	59	2	31943325
Pubmed	Substitution of a single amino acid (aspartic acid for histidine) converts the functional activity of human complement C4B to C4A.	C4A C4B	2.83e-06	2	59	2	2395880
Pubmed	Effects of Complement C4 Gene Copy Number Variations, Size Dichotomy, and C4A Deficiency on Genetic Risk and Clinical Presentation of Systemic Lupus Erythematosus in East Asian Populations.	C4A C4B	2.83e-06	2	59	2	26814708
Pubmed	cDNA clone spanning the alpha-gamma subunit junction in the precursor of the murine fourth complement component (C4).	C4A C4B	2.83e-06	2	59	2	6192448
Pubmed	Complete primary structure of human C4a anaphylatoxin.	C4A C4B	2.83e-06	2	59	2	6167582
Pubmed	Identification of the size and antigenic determinants of the human C4 gene by a polymerase chain-reaction-based amplification method.	C4A C4B	2.83e-06	2	59	2	16908004
Pubmed	Slp is an essential component of an EDTA-resistant activation pathway of mouse complement.	C4A C4B	2.83e-06	2	59	2	1438267
Pubmed	Structural studies on the murine fourth component of complement (C4). IV. Demonstration that C4 and Slp are encoded by separate loci.	C4A C4B	2.83e-06	2	59	2	7365238
Pubmed	Severe epilepsy, retardation, and dysmorphic features with a 2q deletion including SCN1A and SCN2A.	SCN1A SCN2A	2.83e-06	2	59	2	15249644
Pubmed	Genetic deficiency of complement isoforms C4A or C4B predicts improved survival of metastatic renal cell carcinoma.	C4A C4B	2.83e-06	2	59	2	19150565
Pubmed	Interaction between the labile binding sites of the fourth (C4) and fifth (C5) human complement proteins and erythrocyte cell membranes.	C4A C4B	2.83e-06	2	59	2	7391573
Pubmed	Elevated levels of endogenous apoptotic DNA and IFN-alpha in complement C4-deficient mice: implications for induction of systemic lupus erythematosus.	C4A C4B	2.83e-06	2	59	2	17506029
Pubmed	Peritubular capillary C4d deposition in lupus nephritis different from antibody-mediated renal rejection.	C4A C4B	2.83e-06	2	59	2	17971360
Interaction	SCN4B interactions	SCN1A SCN2A SCN8A	9.53e-07	8	53	3	int:SCN4B
Cytoband	8p11.23	LETM2 PLPP5	1.06e-04	12	59	2	8p11.23
Cytoband	2q24.3	SCN1A SCN2A	1.93e-04	16	59	2	2q24.3
Cytoband	6q23.2	TAAR9 TAAR6	4.78e-04	25	59	2	6q23.2
Cytoband	1q41	IARS2 USH2A	3.30e-03	66	59	2	1q41
Cytoband	6p21.3	VPS52 C4A C4B	4.14e-03	250	59	3	6p21.3
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN1A SCN2A SCN8A	1.28e-06	9	46	3	1203
GeneFamily	Carboxypeptidases	CPA6 CPA1 CPB1	1.99e-05	21	46	3	1321
GeneFamily	C3 and PZP like, alpha-2-macroglobulin domain containing	C4A C4B	2.25e-04	9	46	2	1234
GeneFamily	Trace amine receptors	TAAR9 TAAR6	2.25e-04	9	46	2	188
GeneFamily	AT-rich interaction domain containing	ARID3A ARID3C	6.51e-04	15	46	2	418
GeneFamily	Complement system\|Sushi domain containing	C4A C4B	3.78e-03	36	46	2	492
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	C4A C4B	3.99e-03	37	46	2	454
GeneFamily	Forkhead boxes	FOXB1 FOXB2	5.35e-03	43	46	2	508
Coexpression	MCCLUNG_CREB1_TARGETS_DN	TRHR SPIN1 C4A C4B	1.03e-05	60	59	4	MM654
Coexpression	GAO_LARGE_INTESTINE_24W_C5_LGR5POS_STEM_CELL	CPA6 GJB1 ATP10B SFN	1.03e-05	60	59	4	M39155
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXB7 CPA1 CPB1 GCNT1	2.29e-06	70	59	4	5720505ef03d65c73028616c808420e282823bde
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH CPA1 SLC6A15 CPB1 GCNT1	2.74e-06	166	59	5	b7f303203068b205f382788815df487a0ea148ed
ToppCell	3'-Broncho-tracheal-Immune_Lymphocytic-Lymphocytic_T/NK-natural_killer_cell-NK_cells-\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	PCNX2 DPY19L3 ARID3A SEC22C GPR174	3.55e-06	175	59	5	26bd957498e41a3f1ffa60d3effa27ca8c4ba631
ToppCell	ILEUM-non-inflamed-(5)_Plasmablasts\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CFAP47 GGH CLPTM1L ARID3A PLPP5	3.96e-06	179	59	5	58c8996120637315dcbd1991a71516c09173051e
ToppCell	cellseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CPA1 ATP10B C4A CPB1 C4B	4.78e-06	186	59	5	7812ed80d2378aca9957ef22fc3c8fb7fb58434b
ToppCell	Smart-seq2-tissue-resident_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell\|tissue-resident_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GGH CLPTM1L PLPP5 C4A C4B	4.91e-06	187	59	5	c80e03d5aa498b4eecbc46565fabf9b5be10c71c
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJB1 ARID3A ATP10B GCNT1 SFN	6.01e-06	195	59	5	9c24ebce2e3e00b8b692c62a22a53b7d59f0eabb
ToppCell	Parenchymal-10x5prime-Stromal-Mesofibroblastic\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CPA1 ATP10B C4A CPB1 C4B	6.32e-06	197	59	5	88a86286b9c3ea3b076d7464faec42d0392ee7f8
ToppCell	Parenchymal-10x5prime-Stromal-Mesofibroblastic-Mesothelia\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CPA1 ATP10B C4A CPB1 C4B	6.32e-06	197	59	5	2773d2eb5f232a7e49da116efffcb6bf5eb90810
ToppCell	Biopsy_Other_PF-Mesenchymal-Mesothelial_cells\|Biopsy_Other_PF / Sample group, Lineage and Cell type	VGLL2 CPA1 C4A CPB1 C4B	6.48e-06	198	59	5	86736f01e61bf4961f060b24ee1f1f48340737dd
ToppCell	Biopsy_Control_(H.)-Mesenchymal-Mesothelial_cells\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	CPA1 ATP10B C4A CPB1 C4B	6.64e-06	199	59	5	ca970114b5aef4518ce580897a62ac88688b2671
ToppCell	Biopsy_IPF-Mesenchymal-Mesothelial_cells\|Biopsy_IPF / Sample group, Lineage and Cell type	CPA1 ATP10B C4A CPB1 C4B	6.80e-06	200	59	5	553386523fd8f8f36617a0d81032224b7ddce442
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH GJB1 CPA1 CPB1	8.44e-06	97	59	4	16947da747504c2edb9f2e7ee6f05babda0fae60
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH GJB1 CPA1 CPB1	1.20e-05	106	59	4	3aa55c3db4e4abd39c8f2f89f2516927d94ad9d7
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH GJB1 CPA1 CPB1	1.20e-05	106	59	4	c890c838785dfeda30f3b563194da9cfb49b157a
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH CPA1 SLC6A15 CPB1	5.06e-05	153	59	4	39ac25c48e73538f1c10f37bea386e0e88d3e8d0
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_1\|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.	DPY19L3 NIPSNAP3B SCN1A USH2A	5.73e-05	158	59	4	1f94622186d8329357fa06785e03eeacf29ab1ce
ToppCell	droplet-Lung-immune-endo-depleted-3m-Lymphocytic-Zbtb32+_B\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM17 ARID3A PLPP5 SFN	6.17e-05	161	59	4	249c2b97cc25de5053f5048ee354615df49b2081
ToppCell	droplet-Marrow-BM-30m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NEK4 HYAL1 C4B KIFC2	6.32e-05	162	59	4	75df7ff779a3b9159ba97d852da1f8df650b9ce5
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH CPA1 SLC6A15 CPB1	6.32e-05	162	59	4	922ecea81063095b8dd9ac9f9792bf551edbb848
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARID3A PLPP5 SCN8A SFN	6.63e-05	164	59	4	b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ARID3A PLPP5 SCN8A SFN	6.63e-05	164	59	4	a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCell	Bronchial_Brush-Epithelial-Goblet_2\|Bronchial_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	HOXB7 HYAL1 ATP10B SFN	6.94e-05	166	59	4	8ac0a769be886d16642e7e6334471ebadd1a426b
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	GJB1 POLR3B C4A PTPRU	6.94e-05	166	59	4	2e4cb4056e6b0c43290a5588ff525f5f05b8beee
ToppCell	356C-Epithelial_cells-Epithelial-D_(AT2)\|356C / Donor, Lineage, Cell class and subclass (all cells)	GJB1 POLR3B C4A PTPRU	6.94e-05	166	59	4	eb8d972326a734549675307e411fc795af66da70
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Myeloid-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR174 CPA1 ARID3C SFN	7.27e-05	168	59	4	29a6c3ba69e03ccb19efb8ac177b9a162dc1ea43
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Myeloid\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR174 CPA1 ARID3C SFN	7.27e-05	168	59	4	4297be958a4754677df7cf73feba19b0d76f1b4a
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB1 CPA1 CPB1 EXTL3	8.33e-05	174	59	4	165e14cad57e90aa247dcecfaa3c2e8ff2a470ad
ToppCell	facs-Pancreas-Exocrine-18m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GJB1 CPA1 CPB1 EXTL3	8.33e-05	174	59	4	4289dfc7613db4bb3d706b9b65d06e84c0c53558
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-nan\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH GJB1 CPA1 CPB1	8.71e-05	176	59	4	12bccbd56742fcfe19749da802ea1cf62ec9a872
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH GJB1 CPA1 CPB1	9.10e-05	178	59	4	415a02ad14df9deba988990118b00fb84ee524a8
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH GJB1 CPA1 CPB1	9.70e-05	181	59	4	cf8f7798559fedf91ee21b3ebc93171cfd14f89f
ToppCell	droplet-Pancreas-PANCREAS\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH GJB1 CPA1 CPB1	9.91e-05	182	59	4	ecb8c1d0b9e0766fae4dd2568456eb78a3cfce9a
ToppCell	droplet-Pancreas-PANCREAS-30m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GGH GJB1 CPA1 CPB1	9.91e-05	182	59	4	cf1ccfc4709364763fa73e60d5f2c05ce268d5c1
ToppCell	343B-Fibroblasts-Fibroblast-E\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	POLR3B NIPSNAP3B SCN2A PTPRU	1.06e-04	185	59	4	02cbf492bc40abebaa93a3a208888afae72fbe06
ToppCell	343B-Fibroblasts-Fibroblast-E-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	POLR3B NIPSNAP3B SCN2A PTPRU	1.06e-04	185	59	4	1b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell	5'-Adult-Appendix-Epithelial-epithelial_progenitor_cell-TA\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GGH GJB1 HOXB7 ATP10B	1.08e-04	186	59	4	9f9297c3eb360144b911024f6929255f9b3708e2
ToppCell	IPF-Lymphoid-B_Plasma\|Lymphoid / Disease state, Lineage and Cell class	GGH PLPP5 C4A C4B	1.08e-04	186	59	4	f9c21daf905d0bb0e0e769ca4bb069ea4b1ba25b
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 SCN1A SCN2A SCN8A	1.08e-04	186	59	4	7278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GGH GJB1 GCNT1 SFN	1.12e-04	188	59	4	b3cae49f0665ace0016a6441cbf9ae40755b0ea3
ToppCell	5'-Adult-Appendix-Epithelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GGH GJB1 HOXB7 ATP10B	1.12e-04	188	59	4	a7dafee7c15ccad24b0eb2b9e2e600691bc357b6
ToppCell	5'-Adult-Appendix-Epithelial-epithelial_progenitor_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GGH GJB1 HOXB7 ATP10B	1.15e-04	189	59	4	6edc44adfd7dc292fe627f3bceb440d03be99301
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-plasma_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GGH CLPTM1L PLPP5 C4B	1.17e-04	190	59	4	76b747bafff09bf8375a5717c9f213cbfb405bac
ToppCell	Globus_pallidus-Neuronal\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PCNX2 SCN2A SCN8A KIFC2	1.17e-04	190	59	4	416de85d8841dac883faa6f5339b2fb461a09e82
ToppCell	Entopeduncular-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PCNX2 SCN2A TRPC5 SLC6A15	1.19e-04	191	59	4	5d24022cec293bc8d9e978ae99a109e660bb8f83
ToppCell	Entopeduncular-Neuronal-Inhibitory\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	PCNX2 SCN2A TRPC5 SLC6A15	1.19e-04	191	59	4	73dae4cdea86aec62393ad7303dc7375a6b3fc86
ToppCell	COVID-19_Moderate-Plasmablast\|COVID-19_Moderate / disease group, cell group and cell class	GGH CLPTM1L ARID3A PLPP5	1.22e-04	192	59	4	25c6c7a244190f82c7feab874bdec12490b7de4d
ToppCell	Entopeduncular-Neuronal\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SCN2A TRPC5 SCN8A SLC6A15	1.22e-04	192	59	4	4c35e5c28a40b439044797ba1f06cb7c36b2a8de
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 SCN1A SCN2A SCN8A	1.24e-04	193	59	4	be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCell	Posterior_cortex-Neuronal\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	PCNX2 SCN2A SCN8A SLC6A15	1.24e-04	193	59	4	b4989e3436e84dbec3789b46057e0f7a0ebf09d4
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 SCN1A SCN2A SCN8A	1.24e-04	193	59	4	0c652ebe22ce5d2927599dd97ef1920547858395
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PCNX2 SCN1A SCN2A SCN8A	1.24e-04	193	59	4	8689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_B_plasma\|lymph-node_spleen / Manually curated celltypes from each tissue	GGH CLPTM1L ARID3A PLPP5	1.27e-04	194	59	4	42f43cac0dec704afd18143192e3ab68360ea076
ToppCell	10x_3'_v3-thymus_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|thymus_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	GGH CLPTM1L ARID3A PLPP5	1.27e-04	194	59	4	ffba703f61faaac8b4b9a5e46cd335214303de7b
ToppCell	severe-Lymphocytic-Plasmablast\|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	GGH CLPTM1L ARID3A PLPP5	1.29e-04	195	59	4	43ff1eed563c647bc5b7b06ffe136210653c3a83
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJB1 ARID3A ATP10B GCNT1	1.32e-04	196	59	4	0df0dbe60e6f643912e5ff30c22415a0513f9bf1
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJB1 ARID3A ATP10B GCNT1	1.32e-04	196	59	4	153326be031a58b720da4dab57edd8936d513f8e
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Epithelial-mature_enterocytic-Colonocyte\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJB1 ARID3A ATP10B GCNT1	1.32e-04	196	59	4	b7748618aaf3ace40940be1b6ca2148e941541a2
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Epithelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GJB1 ARID3A GCNT1 SFN	1.32e-04	196	59	4	53dcac5e34c08c67a897dd5fbfbe88ea37e15585
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPA6 GJB1 ARID3A GCNT1	1.37e-04	198	59	4	ad9fb53cd216af9bc9998d6b3bd0255b45e0dbfb
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPA6 GJB1 ARID3A GCNT1	1.37e-04	198	59	4	7c4993be089979e79ca1a160c0c4059c422eac6d
ToppCell	3'-GW_trimst-1-LargeIntestine-Epithelial-epithelial_progenitor_cell-Distal_progenitor\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPA6 GJB1 ARID3A GCNT1	1.37e-04	198	59	4	edf3e1c2be9df5690492b9c8fc25e7e48ed5c92c
ToppCell	Striatum-Neuronal-Inhibitory-iN2(Gad1Gad2)\|Striatum / BrainAtlas - Mouse McCarroll V32	GPR174 TRPC5 CPB1	1.89e-04	84	59	3	9417fffe0ba79f5851920258dcd0f6c09218be13
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	CFAP47 TRHR ARID3C	2.72e-04	95	59	3	ffbf3e362384c87b9db690ed39cd215e1f68375c
Drug	NSC-333758	CPA6 CPA1 CPB1	3.29e-07	6	59	3	CID000100086
Drug	hippuryl-L-arginine	CPA6 CPA1 C4A CPB1	4.94e-07	25	59	4	CID000096815
Drug	SQ24798	CPA6 CPA1 CPB1	5.74e-07	7	59	3	CID000194328
Drug	SQ 14,603	CPA6 CPA1 CPB1	9.17e-07	8	59	3	CID000194327
Drug	MTX-Ala	CPA6 CPA1 CPB1	1.37e-06	9	59	3	CID005489429
Drug	MTX-Arg	CPA6 CPA1 CPB1	1.96e-06	10	59	3	CID000131128
Drug	Edeine D	CPA6 CPB1	6.60e-06	2	59	2	CID000170400
Drug	Edeine F	CPA6 CPB1	6.60e-06	2	59	2	CID000194407
Drug	AC1N19IL	CPA6 C4A CPB1	9.04e-06	16	59	3	CID004001756
Drug	2-aminothiophenol	C4A C4B	1.98e-05	3	59	2	ctd:C005464
Drug	Rpch	CPA6 CPA1 EXTL3	2.13e-05	21	59	3	CID000123998
Drug	APETx2 protein, Anthopleura elegantissima	SCN2A SCN8A	3.95e-05	4	59	2	ctd:C501880
Drug	5,5-dimethylhexanoate	CPA6 CPA1	6.57e-05	5	59	2	CID003015183
Drug	ethyl bromacetate	CPA6 CPB1	6.57e-05	5	59	2	CID000007748
Drug	2-phenylethanesulfonate	CPA6 CPA1	6.57e-05	5	59	2	CID000417606
Drug	Tu X	CPA6 CPA1	6.57e-05	5	59	2	CID000449223
Drug	5-bromotryptophan	SCN2A TRPC5	6.57e-05	5	59	2	CID000096735
Drug	BAPACPL	CPA6 CPA1	9.84e-05	6	59	2	CID006439357
Drug	BACPL	CPA6 CPA1	9.84e-05	6	59	2	CID006439356
Drug	APETx1, Anthopleura elegantissima	SCN2A SCN8A	9.84e-05	6	59	2	ctd:C475726
Drug	2-benzyl-4-oxobutanoic acid	CPA6 CPA1	9.84e-05	6	59	2	CID000124534
Drug	Dakh peptide	CPA6 CPA1	9.84e-05	6	59	2	CID003083120
Drug	ochratoxin B methyl ester	CPA6 CPA1	9.84e-05	6	59	2	CID000609664
Drug	benzoylglycylphenyllactate	CPA6 CPA1	9.84e-05	6	59	2	CID000151136
Drug	2-benzyl-3-phosphonopropionic acid	CPA6 CPA1	9.84e-05	6	59	2	CID000127415
Drug	2-benzyl-3-iodo-propanoic acid	CPA6 CPA1	9.84e-05	6	59	2	CID000001542
Drug	ClCH2CO-DL-(N-OH)Leu-OCH3	CPA6 CPA1	9.84e-05	6	59	2	CID000191880
Drug	S)-alpha-benzylmalic acid	CPA6 CPA1	9.84e-05	6	59	2	CID003050318
Drug	5-benzamido-2-benzyl-4-oxopentanoic acid	CPA6 CPA1	9.84e-05	6	59	2	CID000127893
Drug	AC1L9R5V	CPA6 CPA1	9.84e-05	6	59	2	CID000453753
Drug	2-ethyl-2-methylsuccinic acid	CPA6 CPA1	9.84e-05	6	59	2	CID000097776
Drug	3,10-dimethyl-5-deazaisoalloxazine	CPA6 CPA1	9.84e-05	6	59	2	CID000100264
Drug	acetyl-leucyl-glutamyl-histidyl-aspartal	GJB1 TNFSF10	9.84e-05	6	59	2	ctd:C420218
Drug	AC1L5GYK	CPA6 CPA1	9.84e-05	6	59	2	CID000275083
Drug	guanidinoethylmercaptosuccinic acid	CPA6 CPA1 CPB1	1.02e-04	35	59	3	CID000003464
Drug	Arg-Asp	CPA6 POLE CPB1	1.21e-04	37	59	3	CID006426948
Drug	Bradykinin (1-5)	CPA6 C4A CPB1	1.21e-04	37	59	3	CID003081453
Drug	phenylpropynal	CPA6 CPA1	1.37e-04	7	59	2	CID000075740
Drug	NSC89642	CPA6 CPA1	1.37e-04	7	59	2	CID000070889
Drug	histargin	CPA6 CPB1	1.37e-04	7	59	2	CID000146414
Drug	TsCl	CPA6 CPB1	1.37e-04	7	59	2	CID000007397
Drug	beta-dolabrin	CPA6 CPA1	1.37e-04	7	59	2	CID000188981
Drug	gamma-thujaplicin	CPA6 CPA1	1.37e-04	7	59	2	CID000012649
Drug	Gly-Gly-Arg	CPA6 CPB1	1.37e-04	7	59	2	CID000133469
Drug	hippurylglycine	CPA6 CPA1	1.37e-04	7	59	2	CID000096770
Drug	3-phenyllactic acid	GGH CPA6 CPA1	1.41e-04	39	59	3	CID000003848
Drug	Antazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A	SCN2A TRPC5 ETV5 ATP10B GCNT1	1.47e-04	194	59	5	3173_UP
Drug	Cimetidine [51481-61-9]; Down 200; 15.8uM; PC3; HT_HG-U133A	PCNX2 TRAF2 TNFSF10 ETV5 EXTL3	1.54e-04	196	59	5	4063_DN
Drug	Androsterone [53-41-8]; Down 200; 13.8uM; PC3; HT_HG-U133A	PCNX2 TRAF2 TNFSF10 TRPC5 SCN8A	1.66e-04	199	59	5	4635_DN
Drug	Boc-ca-phe	CPA6 CPA1	1.83e-04	8	59	2	CID005487215
Drug	AC1NUP4F	CPA6 CPA1	1.83e-04	8	59	2	CID005487101
Drug	hippuryl-L-phenylalanine	CPA6 CPA1	1.83e-04	8	59	2	CID000098154
Drug	Cck-gly	CPA6 CPB1	1.83e-04	8	59	2	CID000195414
Drug	bromoacetyl-D-arginine	CPA6 CPA1	1.83e-04	8	59	2	CID003082329
Drug	Z-ca-gly-phe	CPA6 CPA1	1.83e-04	8	59	2	CID000195338
Drug	2,3,5,6-tetrafluoro-4-methylbenzyl (Z)-(1RS)-cis-3-(2-chloro-3,3,3-trifluoroprop-1-enyl)-2,2-dimethylcyclopropanecarboxylate	SCN2A SCN8A	1.83e-04	8	59	2	ctd:C489827
Drug	AC1NUT0W	CPA6 CPA1	1.83e-04	8	59	2	CID005492256
Drug	p-guanidino-L-phenylalanine	CPA6 CPB1	2.35e-04	9	59	2	CID000165028
Drug	guanidinopropylsuccinic acid	CPA6 CPB1	2.35e-04	9	59	2	CID000127548
Drug	SP-Gly	CPA6 CPB1	2.35e-04	9	59	2	CID000163663
Drug	Muracein A	CPA6 CPA1	2.35e-04	9	59	2	CID005491013
Drug	FA-Ala-arg	CPA6 CPB1	2.93e-04	10	59	2	CID006444034
Drug	pBF4	ETV5 PTPRU	2.93e-04	10	59	2	CID000123258
Drug	Pareptide	CPA6 CPA1	2.93e-04	10	59	2	CID010086055
Drug	Tyrosine-4-azobenzenearsonate	CPA6 CPA1	2.93e-04	10	59	2	CID009577326
Drug	glutamate thiol	CPA6 CPA1	2.93e-04	10	59	2	CID000125415
Drug	m169	CPA6 CPA1	3.58e-04	11	59	2	CID000010946
Drug	Dns-gltaptv	CPA6 CPA1	3.58e-04	11	59	2	CID005487274
Drug	benzyl sulfonate	CPA6 CPA1	3.58e-04	11	59	2	CID000007532
Drug	NSC-334019	CPA6 CPB1	3.58e-04	11	59	2	CID000100090
Drug	tetrazol-5-imine	CPA6 CPA1	3.58e-04	11	59	2	CID000407223
Drug	FPL 55712	CPA6 C4A CPB1	3.73e-04	54	59	3	CID000105007
Drug	lithium diisopropylamine	CPA6 CPB1	4.28e-04	12	59	2	CID002724682
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN1A SCN2A SCN8A	9.02e-07	10	59	3	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN1A SCN2A SCN8A	9.02e-07	10	59	3	DOID:0080422 (implicated_via_orthology)
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN1A SCN2A SCN8A	1.65e-06	12	59	3	DOID:0060170 (implicated_via_orthology)
Disease	Benign familial infantile epilepsy	SCN2A SCN8A	1.18e-05	3	59	2	cv:C5575231
Disease	Familial benign neonatal epilepsy	SCN2A SCN8A	5.87e-05	6	59	2	C0220669
Disease	Seizure, Febrile, Simple	SCN1A SCN2A	8.20e-05	7	59	2	C0149886
Disease	Seizure, Febrile, Complex	SCN1A SCN2A	8.20e-05	7	59	2	C0751057
Disease	Febrile Convulsions	SCN1A SCN2A	1.40e-04	9	59	2	C0009952
Disease	Generalized Epilepsy with Febrile Seizures Plus	SCN1A SCN2A	1.40e-04	9	59	2	C3502809
Disease	Infantile Severe Myoclonic Epilepsy	SCN1A SCN2A	3.02e-04	13	59	2	C0751122
Disease	MMR-related febrile seizures	SCN1A SCN2A	4.06e-04	15	59	2	EFO_0006519
Disease	Early infantile epileptic encephalopathy with suppression bursts	SCN1A SCN2A	4.63e-04	16	59	2	C0393706
Disease	extrahepatic cholestasis (biomarker_via_orthology)	GJB1 CYP7A1	5.24e-04	17	59	2	DOID:13619 (biomarker_via_orthology)
Disease	Febrile seizure (within the age range of 3 months to 6 years)	SCN1A SCN2A	5.89e-04	18	59	2	HP_0002373
Disease	Epilepsy, Cryptogenic	SCN1A SCN2A SCN8A	6.01e-04	82	59	3	C0086237
Disease	Awakening Epilepsy	SCN1A SCN2A SCN8A	6.01e-04	82	59	3	C0751111
Disease	Aura	SCN1A SCN2A SCN8A	6.01e-04	82	59	3	C0236018
Disease	Neurodevelopmental Disorders	SCN1A SCN2A SCN8A	8.67e-04	93	59	3	C1535926
Disease	anxiety disorder (implicated_via_orthology)	SCN1A SCN2A	8.85e-04	22	59	2	DOID:2030 (implicated_via_orthology)
Disease	lung squamous cell carcinoma (is_implicated_in)	CLPTM1L POLE	1.05e-03	24	59	2	DOID:3907 (is_implicated_in)
Disease	Epilepsy	SCN1A SCN2A SCN8A	1.37e-03	109	59	3	C0014544
Disease	Prostatic Neoplasms	CLPTM1L VPS52 FAF2 TNFSF10 ETV5 GCNT1	1.42e-03	616	59	6	C0033578
Disease	Malignant neoplasm of prostate	CLPTM1L VPS52 FAF2 TNFSF10 ETV5 GCNT1	1.42e-03	616	59	6	C0376358
Disease	sleep quality	POLR3B TRHR VGLL2	1.72e-03	118	59	3	EFO_0005272
Disease	Complement deficiency disease	C4A C4B	1.99e-03	33	59	2	C0272242

Protein segments in the cluster

Peptide	Gene	Start	Entry
SKKAYFLYMYSRYLS	CDC23	111	Q9UJX2
ILKMPFYCLYYYRRA	CDC23	411	Q9UJX2
GYRMKFACYYPRVEY	C4B	1611	P0C0L5
SRVFYLKMKGDYYRY	SFN	116	P31947
AFTLRTQYMKYLYPY	ARID3C	186	A6NKF2
TQYMKYLYPYECETR	ARID3C	191	A6NKF2
HSYSQLLMYPYGYKT	CPA1	306	P15085
CGLYYSYYKQMLQAP	DPY19L3	91	Q6ZPD9
YAQMLLYPYSYKYAT	CPA6	326	Q8N4T0
YSRLARMVVYYLYKN	ATP10B	1106	O94823
MATAPYNYSYIFKYI	RAB14	1	P61106
LSDIYKFIMERFPYY	FOXB2	36	Q5VYV0
IMDELKYYYNGFYLL	LETM2	126	Q2VYF4
RYYIKSIIYYMVTSP	PCNX2	1531	A6NKB5
YYMSPELFSNKPYNY	NEK4	171	P51957
FYEFRTYYLKPSNMN	NIPSNAP3B	36	Q9BS92
AMNYDKLSRSLRYYY	ETV5	416	P41161
TYYLYMKYVHPFIFA	POLE	466	Q07864
YLKYVNMYASIYFLV	GPR174	96	Q9BXC1
LSEIYKFIMDRFPYY	FOXB1	36	Q99853
HYAYSYYPKPVNMTK	PTPRU	776	Q92729
MSSLYYANTLFSKYP	HOXB7	1	P09629
PLKEYYTLMDIAYIY	PCGF2	201	P35227
YMTVYNYYVYPDKTR	HAT1	221	O14929
KVMKNYGRYYIAASY	GGH	46	Q92820
HKYYAYLYSYVMPQA	EXTL3	806	O43909
SAIYYSYYKDMLKAP	DPY19L4	96	Q7Z388
YVFYLLYPGYAMVRL	GJB1	151	P08034
MYSRLFYLKSSYIIY	CXorf1	1	O96002
PKYRHMQTFYRYYSG	DBR1	56	Q9UK59
TTFYCNGLKLKYYYM	CYP7A1	421	P22680
MTIFYSSQLGTYPYY	HYAL1	71	Q12794
FSYPTKYYFMVLVLS	GCNT1	11	Q02742
FQCYLYLFYSPARTM	SEC22C	236	Q9BRL7
NYYAMYLKYLRSVRL	CFAP47	636	Q6ZTR5
YSQMMIYPYSYAYKL	CPB1	306	P15086
MYAFYSLLIYIFYSL	KIFC2	1	Q96AC6
GYRMKFACYYPRVEY	C4A	1611	P0C0L4
YTDVNLKPYMTYEYR	USH2A	3461	O75445
SRYYYYMWKYISPLM	SLC6A15	566	Q9H2J7
YKISRNYYSPIYLMD	TRHR	181	P34981
YYNSAMNPLIYALFY	TAAR6	301	Q96RI8
YYNSAMNPLIYAFFY	TAAR9	301	Q96RI9
RMFNRTYKLYSYSYL	ENTPD6	281	O75354
YYLIMLPFRFTYYTI	FAF2	96	Q96CS3
TFYQMYDKGLVYRSY	IARS2	226	Q9NSE4
LFTYARPKLMYAYNS	OR6Y1	261	Q8NGX8
VLVFGMLYPAYYSYK	REEP3	11	Q6NUK4
PKYEESLYMYLYFVI	SCN1A	1451	P35498
AFTLRTQYMKYLYPY	ARID3A	311	Q99856
YDTQAMKYLSYLLYP	CLPTM1L	396	Q96KA5
LALQMSLYFNTYYFP	TMEM17	41	Q86X19
FYTSRYGYKMCLRIY	TRAF2	381	Q12933
YLSYYRSYLGRLMKV	VPS52	296	Q8N1B4
AYTPYHQKLAYYSKM	VGLL2	21	Q8N8G2
FYITYEKDPVLYMYQ	SPIN1	166	Q9Y657
PKYEDNLYMYLYFVI	SCN2A	1441	Q99250
MTFAYVCYRQYYPPL	PLPP5	221	Q8NEB5
QPKYEDNIYMYIYFV	SCN8A	1431	Q9UQD0
YIYFGPVYYQKLKHM	POLR3B	1001	Q9NW08
MAQLYYKKVNYSPYR	TRPC5	1	Q9UL62
MVQYIYKYTSYPDPI	TNFSF10	206	P50591