Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	calcium ion binding	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 SYT9 CDH23 LRP1B FAT1 FAT2 SULF2 HMCN1 MEGF6 CCDC47 USP32 MACF1 EGFLAM CDH15 RCN3	5.79e-06	749	155	19	GO:0005509
GeneOntologyBiologicalProcess	homophilic cell adhesion via plasma membrane adhesion molecules	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 HMCN1 PTPRR ROBO3 SDK1 CDH15	1.71e-09	187	155	13	GO:0007156
GeneOntologyBiologicalProcess	cell-cell adhesion via plasma-membrane adhesion molecules	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 HMCN1 PTPRR ROBO3 SDK1 CDH15	7.32e-07	313	155	13	GO:0098742
Domain	Cadherin_CS	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 CDH15	3.11e-07	109	155	9	IPR020894
Domain	CADHERIN_1	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 CDH15	4.23e-07	113	155	9	PS00232
Domain	Cadherin	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 CDH15	4.23e-07	113	155	9	PF00028
Domain	CADHERIN_2	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 CDH15	4.56e-07	114	155	9	PS50268
Domain	-	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 CDH15	4.56e-07	114	155	9	2.60.40.60
Domain	CA	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 CDH15	4.92e-07	115	155	9	SM00112
Domain	Cadherin-like	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 CDH15	5.29e-07	116	155	9	IPR015919
Domain	Cadherin	PCDHGA3 CDHR1 FAT3 PCDHB5 PCDHB14 CDH23 FAT1 FAT2 CDH15	6.12e-07	118	155	9	IPR002126
Domain	EGF_CA	FAT3 LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	7.14e-05	122	155	7	SM00179
Domain	EGF-like_Ca-bd_dom	FAT3 LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	7.91e-05	124	155	7	IPR001881
Domain	LAM_G_DOMAIN	FAT3 FAT1 FAT2 EGFLAM	2.70e-04	38	155	4	PS50025
Domain	EGF_1	LAMB4 FAT3 TEK LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	2.85e-04	255	155	9	PS00022
Domain	Laminin_G_2	FAT3 FAT1 FAT2 EGFLAM	3.30e-04	40	155	4	PF02210
Domain	EGF-like_CS	LAMB4 FAT3 TEK LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	3.38e-04	261	155	9	IPR013032
Domain	EGF_2	LAMB4 FAT3 TEK LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	3.77e-04	265	155	9	PS01186
Domain	LamG	FAT3 FAT1 FAT2 EGFLAM	4.78e-04	44	155	4	SM00282
Domain	dsrm	ADARB1 DHX30 ADAD2	5.76e-04	20	155	3	PF00035
Domain	EGF	LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	6.44e-04	126	155	6	PF00008
Domain	DS_RBD	ADARB1 DHX30 ADAD2	6.68e-04	21	155	3	PS50137
Domain	NUT	NUTM2A NUTM2B	6.73e-04	5	155	2	IPR024310
Domain	NUT_N	NUTM2A NUTM2B	6.73e-04	5	155	2	IPR024309
Domain	NUT	NUTM2A NUTM2B	6.73e-04	5	155	2	PF12881
Domain	EGF_CA	FAT3 LRP1B FAT1 HMCN1 MEGF6	7.48e-04	86	155	5	PF07645
Domain	EGF	FAT3 TEK LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	7.86e-04	235	155	8	SM00181
Domain	EGF_3	FAT3 TEK LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	7.86e-04	235	155	8	PS50026
Domain	ADEAMc	ADARB1 ADAD2	1.00e-03	6	155	2	SM00552
Domain	A_deamin	ADARB1 ADAD2	1.00e-03	6	155	2	PF02137
Domain	A_DEAMIN_EDITASE	ADARB1 ADAD2	1.00e-03	6	155	2	PS50141
Domain	A_deamin	ADARB1 ADAD2	1.00e-03	6	155	2	IPR002466
Domain	LRR_6	FBXL15 NOD2 NLRC5 PHLPP1	1.12e-03	55	155	4	PF13516
Domain	EGF-like_dom	FAT3 TEK LRP1B FAT1 FAT2 HMCN1 MEGF6 EGFLAM	1.14e-03	249	155	8	IPR000742
Domain	EGF_Ca-bd_CS	FAT3 LRP1B FAT1 HMCN1 MEGF6	1.29e-03	97	155	5	IPR018097
Domain	Laminin_G	FAT3 FAT1 FAT2 EGFLAM	1.37e-03	58	155	4	IPR001791
Domain	ENaC	ASIC2 ASIC3	1.40e-03	7	155	2	IPR004724
Domain	EGF_CA	FAT3 LRP1B FAT1 HMCN1 MEGF6	1.41e-03	99	155	5	PS01187
Domain	Znf_FYVE_PHD	KDM3A BRPF3 KDM5C SHPRH ZFYVE26 UHRF2	1.43e-03	147	155	6	IPR011011
Domain	-	LRCH2 EPYC FBXL15 LRCH3 NOD2 CMIP NLRC5 PHLPP1 PHLPP2	1.47e-03	321	155	9	3.80.10.10
Domain	ASX_HYDROXYL	FAT3 LRP1B FAT1 HMCN1 MEGF6	1.47e-03	100	155	5	PS00010
Domain	L_dom-like	LRCH2 EPYC FBXL15 LRCH3 NOD2 CMIP NLRC5 PHLPP1 PHLPP2	1.70e-03	328	155	9	IPR032675
Domain	Spectrin_repeat	KRT77 SYNE2 MACF1	1.75e-03	29	155	3	IPR002017
Domain	DHC_N1	DNAH2 DYNC1H1	1.85e-03	8	155	2	PF08385
Domain	Na+channel_ASC_CS	ASIC2 ASIC3	1.85e-03	8	155	2	IPR020903
Domain	Dynein_heavy_dom-1	DNAH2 DYNC1H1	1.85e-03	8	155	2	IPR013594
Domain	EGF-type_Asp/Asn_hydroxyl_site	FAT3 LRP1B FAT1 HMCN1 MEGF6	1.91e-03	106	155	5	IPR000152
Domain	Leu-rich_rpt	LRCH2 EPYC FBXL15 LRCH3 NOD2 NLRC5 PHLPP1 PHLPP2	1.95e-03	271	155	8	IPR001611
Domain	CH	LRCH2 LRCH3 SYNE2 MACF1	2.09e-03	65	155	4	SM00033
Domain	SPEC	KRT77 SYNE2 MACF1	2.33e-03	32	155	3	SM00150
Domain	Spectrin/alpha-actinin	KRT77 SYNE2 MACF1	2.33e-03	32	155	3	IPR018159
Domain	ASC	ASIC2 ASIC3	2.37e-03	9	155	2	PF00858
Domain	ASC	ASIC2 ASIC3	2.37e-03	9	155	2	PS01206
Domain	Na+channel_ASC	ASIC2 ASIC3	2.37e-03	9	155	2	IPR001873
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	THSD7A MYCBP2 DOCK10 SULF2 AATK MEGF6 UBR5 SYNE2 PHLPP1 MACF1 CLEC16A	8.12e-09	225	159	11	12168954
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ZNF609 MAN2B2 POLR1A MYCBP2 EVC ADARB1 RXRA LRCH3 RLF CMIP MEGF6 INTS2 PTPRR RPTOR NAXD SHPRH NLRC5 MACF1 AKAP13 CLEC16A ALG12 WNK2 NLK CDH15 CAP2	1.93e-08	1489	159	25	28611215
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LRCH2 TMEM94 HIPK1 DOCK10 CAMTA2 DHX30 UBR5 MACF1 MAPKBP1 PUM1 KIF17 CLEC16A DYNC1H1	5.50e-08	407	159	13	12693553
Pubmed	Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.	FAT3 FAT1 FAT2	9.38e-08	3	159	3	15744052
Pubmed	Functional proteomics mapping of a human signaling pathway.	THSD7A MYCBP2 HIPK1 RXRA DHX30 RLF UBR5 MACF1 PUM1 UHRF2 SDK1 DYNC1H1 CAP2 HDLBP	6.33e-07	591	159	14	15231748
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	NPC1 ERCC2 MYCBP2 TMEM94 ARHGEF11 DHX30 NOD2 FAT1 AATK MEGF6 RPTOR NLRC5 AKAP13 ZFYVE26 MAPKBP1 PUM1 MED13 DYNC1H1 WNK2	8.02e-07	1105	159	19	35748872
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	FAT3 FAT1 FAT2	3.24e-06	7	159	3	16059920
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	USP36 BRPF3 ERCC2 ZNF609 MTHFD2 KDM5C FAT3 HMGXB4 E2F2 TAF6L FAT1 SULF2 ARSB UBR5 PIK3R2 RPTOR MACF1 CDH15	3.89e-06	1116	159	18	31753913
Pubmed	Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.	DOCK10 LCP2 RPTOR MACF1 PYGL AKAP13 DYNC1H1	4.54e-06	143	159	7	30397336
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP36 KDM3A BRPF3 ZNF609 CAND2 KDM5C SULF2 INTS2 RPTOR TET1 MED13 WNK2	6.39e-06	529	159	12	14621295
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NPC1 HDAC9 KDM3A MYCBP2 HIPK1 ADARB1 LRP1B DHX30 ZNF18 HEATR6 STXBP1 PSMG1 USP32 MAP3K10 MACF1 ABHD12 MED13 DYNC1H1 CAP2	7.15e-06	1285	159	19	35914814
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ZNF609 ADAMTS3 ARHGEF11 ZFYVE26 CLEC16A DYNC1H1	8.71e-06	104	159	6	9205841
Pubmed	A human MAP kinase interactome.	HDAC9 HIPK1 LCP2 ARHGEF11 PIK3R2 MAP3K10 MACF1 AKAP13 WNK2 CAP2 HDLBP	1.60e-05	486	159	11	20936779
Pubmed	Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.	RHOXF2 RHOXF2B	2.08e-05	2	159	2	12087094
Pubmed	PHLPP isoforms differentially regulate Akt isoforms and AS160 affecting neuronal insulin signaling and insulin resistance via Scribble.	PHLPP1 PHLPP2	2.08e-05	2	159	2	36376971
Pubmed	Comparative analyses of relative ERCC3 and ERCC6 mRNA levels in gliomas and adjacent non-neoplastic brain.	ERCC2 ERCC3	2.08e-05	2	159	2	8876669
Pubmed	ASICs mediate fast excitatory synaptic transmission for tactile discrimination.	ASIC2 ASIC3	2.08e-05	2	159	2	38359825
Pubmed	PHLPPing through history: a decade in the life of PHLPP phosphatases.	PHLPP1 PHLPP2	2.08e-05	2	159	2	27913677
Pubmed	The c-Jun N-terminal kinase (JNK)-binding protein (JNKBP1) acts as a negative regulator of NOD2 protein signaling by inhibiting its oligomerization process.	NOD2 MAPKBP1	2.08e-05	2	159	2	22700971
Pubmed	Role of ERCC2 and ERCC3 gene polymorphisms in the development of osteosarcoma.	ERCC2 ERCC3	2.08e-05	2	159	2	27051024
Pubmed	Co-Mutation of FAT3 and LRP1B in Lung Adenocarcinoma Defines a Unique Subset Correlated With the Efficacy of Immunotherapy.	FAT3 LRP1B	2.08e-05	2	159	2	35069585
Pubmed	TET1 promotes RXRα expression and adipogenesis through DNA demethylation.	RXRA TET1	2.08e-05	2	159	2	33684567
Pubmed	Ras-associating domain proteins: a new class of cyclic nucleotide-gated channel modulators.	PHLPP1 PHLPP2	2.08e-05	2	159	2	22183406
Pubmed	Long noncoding RNA FER1L4 regulates rheumatoid arthritis via targeting NLRC5.	FER1L4 NLRC5	2.08e-05	2	159	2	31694750
Pubmed	Acid sensing ion channels 2 and 3 are required for inhibition of visceral nociceptors by benzamil.	ASIC2 ASIC3	2.08e-05	2	159	2	17467171
Pubmed	Antitumor immunity and prognosis value elicited by FAT3 and LRP1B co-mutation in endometrial cancer.	FAT3 LRP1B	2.08e-05	2	159	2	38696842
Pubmed	Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.	RHOXF2 RHOXF2B	2.08e-05	2	159	2	16465597
Pubmed	XPB mediated retroviral cDNA degradation coincides with entry to the nucleus.	ERCC2 ERCC3	2.08e-05	2	159	2	21167544
Pubmed	Cloning and characterization of the 5'-flanking region of the Ehox gene.	RHOXF2 RHOXF2B	2.08e-05	2	159	2	16414020
Pubmed	Haplotype analysis on relationship of ERCC2 and ERCC3 gene polymorphisms with osteosarcoma risk in Chinese young population.	ERCC2 ERCC3	2.08e-05	2	159	2	28474168
Pubmed	Polymorphisms in the two helicases ERCC2/XPD and ERCC3/XPB of the transcription factor IIH complex and risk of lung cancer: a case-control analysis in a Chinese population.	ERCC2 ERCC3	2.08e-05	2	159	2	16835333
Pubmed	Biochemical characterization of the phosphatase domain of the tumor suppressor PH domain leucine-rich repeat protein phosphatase.	PHLPP1 PHLPP2	2.08e-05	2	159	2	24892992
Pubmed	Specific association of a CLEC16A/KIAA0350 polymorphism with NOD2/CARD15(-) Crohn's disease patients.	NOD2 CLEC16A	2.08e-05	2	159	2	19337309
Pubmed	Chronic hyperalgesia induced by repeated acid injections in muscle is abolished by the loss of ASIC3, but not ASIC1.	ASIC2 ASIC3	2.08e-05	2	159	2	14659506
Pubmed	Mammalian ASIC2a and ASIC3 subunits co-assemble into heteromeric proton-gated channels sensitive to Gd3+.	ASIC2 ASIC3	2.08e-05	2	159	2	10842183
Pubmed	A 3' --> 5' XPB helicase defect in repair/transcription factor TFIIH of xeroderma pigmentosum group B affects both DNA repair and transcription.	ERCC2 ERCC3	2.08e-05	2	159	2	8663148
Pubmed	Deletion of the acid-sensing ion channel ASIC3 prevents gastritis-induced acid hyperresponsiveness of the stomach-brainstem axis.	ASIC2 ASIC3	2.08e-05	2	159	2	17531389
Pubmed	G quadruplexes are genomewide targets of transcriptional helicases XPB and XPD.	ERCC2 ERCC3	2.08e-05	2	159	2	24609361
Pubmed	Lack of CAK complex accumulation at DNA damage sites in XP-B and XP-B/CS fibroblasts reveals differential regulation of CAK anchoring to core TFIIH by XPB and XPD helicases during nucleotide excision repair.	ERCC2 ERCC3	2.08e-05	2	159	2	23083890
Pubmed	Loss of acid-sensing ion channel 2 enhances pulmonary vascular resistance and hypoxic pulmonary hypertension.	ASIC2 ASIC3	2.08e-05	2	159	2	31169471
Pubmed	Aberrant expression of PHLPP1 and PHLPP2 correlates with poor prognosis in patients with hypopharyngeal squamous cell carcinoma.	PHLPP1 PHLPP2	2.08e-05	2	159	2	25793736
Pubmed	Trichothiodystrophy, a transcription syndrome.	ERCC2 ERCC3	2.08e-05	2	159	2	11335038
Pubmed	Transcriptional regulation of the TFIIH transcription repair components XPB and XPD by the hepatitis B virus x protein in liver cells and transgenic liver tissue.	ERCC2 ERCC3	2.08e-05	2	159	2	11278765
Pubmed	Phenotype-specific adverse effects of XPD mutations on human prenatal development implicate impairment of TFIIH-mediated functions in placenta.	ERCC2 ERCC3	2.08e-05	2	159	2	22234153
Pubmed	Rhox homeobox gene cluster: recent duplication of three family members.	RHOXF2 RHOXF2B	2.08e-05	2	159	2	16496311
Pubmed	Pleckstrin Homology Domain Leucine-rich Repeat Protein Phosphatase Acts as a Tumor Suppressor in Oral Squamous Cell Carcinoma.	PHLPP1 PHLPP2	2.08e-05	2	159	2	38602289
Pubmed	Loss of PHLPP protects against colitis by inhibiting intestinal epithelial cell apoptosis.	PHLPP1 PHLPP2	2.08e-05	2	159	2	26187040
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	ZNF609 RHOXF2 TAF6L DZANK1 MEGF6 NUTM2B MAPKBP1 DMPK PUM1 KIF17 WNK2 NLK	2.53e-05	608	159	12	16713569
Pubmed	Different contributions of ASIC channels 1a, 2, and 3 in gastrointestinal mechanosensory function.	ASIC2 ASIC3	6.21e-05	3	159	2	15987792
Pubmed	Mst1 is an interacting protein that mediates PHLPPs' induced apoptosis.	PHLPP1 PHLPP2	6.21e-05	3	159	2	20513427
Pubmed	Pleckstrin Homology (PH) Domain Leucine-rich Repeat Protein Phosphatase Controls Cell Polarity by Negatively Regulating the Activity of Atypical Protein Kinase C.	PHLPP1 PHLPP2	6.21e-05	3	159	2	27760826
Pubmed	PTEN and PHLPP crosstalk in cancer cells and in TGFβ-activated stem cells.	PHLPP1 PHLPP2	6.21e-05	3	159	2	32294598
Pubmed	Up-regulation of acid-sensing ion channels in the capsule of the joint in frozen shoulder.	ASIC2 ASIC3	6.21e-05	3	159	2	26033064
Pubmed	Distinct roles for the XPB/p52 and XPD/p44 subcomplexes of TFIIH in damaged DNA opening during nucleotide excision repair.	ERCC2 ERCC3	6.21e-05	3	159	2	17466626
Pubmed	Acid-sensing ion channels ASIC2 and ASIC3 do not contribute to mechanically activated currents in mammalian sensory neurones.	ASIC2 ASIC3	6.21e-05	3	159	2	14990679
Pubmed	microRNA-224 promotes cell proliferation and tumor growth in human colorectal cancer by repressing PHLPP1 and PHLPP2.	PHLPP1 PHLPP2	6.21e-05	3	159	2	23846336
Pubmed	The rhox homeobox gene family shows sexually dimorphic and dynamic expression during mouse embryonic gonad development.	RHOXF2 RHOXF2B	6.21e-05	3	159	2	18562707
Pubmed	Mice lacking acid-sensing ion channels (ASIC) 1 or 2, but not ASIC3, show increased pain behaviour in the formalin test.	ASIC2 ASIC3	6.21e-05	3	159	2	18801682
Pubmed	The phosphatase PHLPP controls the cellular levels of protein kinase C.	PHLPP1 PHLPP2	6.21e-05	3	159	2	18162466
Pubmed	ASIC2b-dependent regulation of ASIC3, an essential acid-sensing ion channel subunit in sensory neurons via the partner protein PICK-1.	ASIC2 ASIC3	6.21e-05	3	159	2	14976185
Pubmed	Generation of DNA single-strand displacement by compromised nucleotide excision repair.	ERCC2 ERCC3	6.21e-05	3	159	2	22863773
Pubmed	Mutation in EGFP domain of LDL receptor-related protein 6 impairs cellular LDL clearance.	NPC1 APOB	6.21e-05	3	159	2	18948618
Pubmed	Identification of three novel non-classical cadherin genes through comprehensive analysis of large cDNAs.	CDHR1 CDH23	6.21e-05	3	159	2	11597768
Pubmed	Acid-sensing ion channels contribute to the effect of extracellular acidosis on proliferation and migration of A549 cells.	ASIC2 ASIC3	6.21e-05	3	159	2	28618956
Pubmed	Role of acid-sensing ion channels in hypoxia- and hypercapnia-induced ventilatory responses.	ASIC2 ASIC3	6.21e-05	3	159	2	29474404
Pubmed	Acid-sensing ion channels (ASICs) in mouse skeletal muscle afferents are heteromers composed of ASIC1a, ASIC2, and ASIC3 subunits.	ASIC2 ASIC3	6.21e-05	3	159	2	23109675
Pubmed	Localization and comparative analysis of acid-sensing ion channel (ASIC1, 2, and 3) mRNA expression in mouse colonic sensory neurons within thoracolumbar dorsal root ganglia.	ASIC2 ASIC3	6.21e-05	3	159	2	17177258
Pubmed	The expression of NOD2, NLRP3 and NLRC5 and renal injury in anti-neutrophil cytoplasmic antibody-associated vasculitis.	NOD2 NLRC5	6.21e-05	3	159	2	31186034
Pubmed	Acid-sensing ion channels contribute to the effect of acidosis on the function of dendritic cells.	ASIC2 ASIC3	6.21e-05	3	159	2	21321108
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	6.21e-05	3	159	2	26542179
Pubmed	Acid sensing ion channels regulate neuronal excitability by inhibiting BK potassium channels.	ASIC2 ASIC3	6.21e-05	3	159	2	22960074
Pubmed	ASIC2a and ASIC3 heteromultimerize to form pH-sensitive channels in mouse cardiac dorsal root ganglia neurons.	ASIC2 ASIC3	6.21e-05	3	159	2	19590043
Pubmed	Identification and Function of Acid-sensing Ion Channels in RAW 264.7 Macrophage Cells.	ASIC2 ASIC3	6.21e-05	3	159	2	30074209
Pubmed	The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.	NUTM2A NUTM2B	6.21e-05	3	159	2	22456610
Pubmed	Downregulation of PHLPP induced by endoplasmic reticulum stress promotes eIF2α phosphorylation and chemoresistance in colon cancer.	PHLPP1 PHLPP2	6.21e-05	3	159	2	34663797
Pubmed	Expression and role of oncogenic miRNA-224 in esophageal squamous cell carcinoma.	PHLPP1 PHLPP2	6.21e-05	3	159	2	26245343
Pubmed	Heteromultimers of DEG/ENaC subunits form H+-gated channels in mouse sensory neurons.	ASIC2 ASIC3	6.21e-05	3	159	2	11854527
Pubmed	TFIIH subunit alterations causing xeroderma pigmentosum and trichothiodystrophy specifically disturb several steps during transcription.	ERCC2 ERCC3	6.21e-05	3	159	2	25620205
Pubmed	Modulation of Acid-sensing Ion Channel 1a by Intracellular pH and Its Role in Ischemic Stroke.	ASIC2 ASIC3	6.21e-05	3	159	2	27402850
Pubmed	ARCH domain of XPD, an anchoring platform for CAK that conditions TFIIH DNA repair and transcription activities.	ERCC2 ERCC3	6.21e-05	3	159	2	23382212
Pubmed	PHLPP and a second isoform, PHLPP2, differentially attenuate the amplitude of Akt signaling by regulating distinct Akt isoforms.	PHLPP1 PHLPP2	6.21e-05	3	159	2	17386267
Pubmed	Expression of acid-sensing ion channels of gastric mucosa from patients with Henoch-Schönlein purpura.	ASIC2 ASIC3	6.21e-05	3	159	2	22157923
Pubmed	Basal transcription defect discriminates between xeroderma pigmentosum and trichothiodystrophy in XPD patients.	ERCC2 ERCC3	6.21e-05	3	159	2	12820975
Pubmed	The RHOX5 homeodomain protein mediates transcriptional repression of the netrin-1 receptor gene Unc5c.	RHOXF2 RHOXF2B	6.21e-05	3	159	2	18077458
Pubmed	Subunit-dependent high-affinity zinc inhibition of acid-sensing ion channels.	ASIC2 ASIC3	6.21e-05	3	159	2	15470133
Pubmed	Structure of the N terminus of cadherin 23 reveals a new adhesion mechanism for a subset of cadherin superfamily members.	CDHR1 CDH23	6.21e-05	3	159	2	20498078
Pubmed	Cadherin 23 and protocadherin 15 interact to form tip-link filaments in sensory hair cells.	CDH23 CDH15	6.21e-05	3	159	2	17805295
Pubmed	MicroRNA-141 promotes the proliferation of non-small cell lung cancer cells by regulating expression of PHLPP1 and PHLPP2.	PHLPP1 PHLPP2	6.21e-05	3	159	2	24945731
Pubmed	Gene-environment interactions between ERCC2, ERCC3, XRCC1 and cadmium exposure in nasal polyposis disease.	ERCC2 ERCC3	6.21e-05	3	159	2	27838878
Pubmed	An Xpb mouse model for combined xeroderma pigmentosum and cockayne syndrome reveals progeroid features upon further attenuation of DNA repair.	ERCC2 ERCC3	6.21e-05	3	159	2	19114557
Pubmed	Inhibition of PHLPP1/2 phosphatases rescues pancreatic β-cells in diabetes.	PHLPP1 PHLPP2	6.21e-05	3	159	2	34348155
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	USP36 KDM3A LAMB4 POLR1A MYCBP2 TAF6L UBR5 OTUD6B KRT77 USP32 SHPRH PHLPP1 PYGL MPP7 PHLPP2	6.26e-05	1005	159	15	19615732
Pubmed	Rrn3 becomes inactivated in the process of ribosomal DNA transcription.	ERCC2 ERCC3 POLR1A	8.61e-05	19	159	3	12646563
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	POLR1A LRCH3 DHX30 CCDC47 MACF1 PYGL AKAP13 PUM1 UHRF2 DYNC1H1 HDLBP	1.08e-04	601	159	11	33658012
Pubmed	Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	USP36 KLHL1 LRCH2 DNAH2 CNTN3	1.14e-04	103	159	5	10819331
Pubmed	Stomatin modulates gating of acid-sensing ion channels.	ASIC2 ASIC3	1.24e-04	4	159	2	15471860
Pubmed	LRCH proteins: a novel family of cytoskeletal regulators.	LRCH2 LRCH3	1.24e-04	4	159	2	20805893
Pubmed	Both XPD alleles contribute to the phenotype of compound heterozygote xeroderma pigmentosum patients.	ERCC2 ERCC3	1.24e-04	4	159	2	19934020
Pubmed	PHLPP-mediated dephosphorylation of S6K1 inhibits protein translation and cell growth.	PHLPP1 PHLPP2	1.24e-04	4	159	2	21986499
Pubmed	PTEN, NHERF1 and PHLPP form a tumor suppressor network that is disabled in glioblastoma.	PHLPP1 PHLPP2	1.24e-04	4	159	2	21804599
Cytoband	Ensembl 112 genes in cytogenetic band chr17q23	HEATR6 INTS2 CCDC47 USP32 MED13	6.47e-05	120	159	5	chr17q23
GeneFamily	Cadherin related	CDHR1 FAT3 CDH23 FAT1 FAT2	4.44e-08	17	110	5	24
GeneFamily	Acid sensing ion channel subunits	ASIC2 ASIC3	3.62e-04	5	110	2	290
GeneFamily	WD repeat domain containing\|ERCC excision repair associated	ERCC2 ERCC3	7.55e-04	7	110	2	1268
GeneFamily	WD repeat domain containing\|Xeroderma pigmentosum complementation groups\|Nucleotide excision repair	ERCC2 ERCC3	1.00e-03	8	110	2	1125
GeneFamily	Adenosine deaminases acting on RNA	ADARB1 ADAD2	1.00e-03	8	110	2	1303
GeneFamily	PHD finger proteins	BRPF3 KDM5C SHPRH UHRF2	2.22e-03	90	110	4	88
GeneFamily	Fibronectin type III domain containing	TEK CNTN3 EGFLAM ROBO3 SDK1	2.96e-03	160	110	5	555
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADCY4 TEK PKHD1L1 SULF2 PLIN5 ROBO3 UHRF2 MPP7	3.23e-07	183	159	8	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	HDAC9 FAT3 DOCK10 IRAG1 ADARB1 MACF1 SDK1 MPP7	3.96e-07	188	159	8	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	HDAC9 FAT3 DOCK10 IRAG1 ADARB1 MACF1 SDK1 MPP7	4.12e-07	189	159	8	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	Parenchymal-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HDAC9 ADCY4 CDH23 TEK PKHD1L1 SULF2 PTPRR MN1	5.64e-07	197	159	8	b0036cf3f7e6edf8e43f16cd2f0f0e80471d2576
ToppCell	3'_v3-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	NPC1 NSUN6 SYNE2 NLRC5 MACF1 AKAP13 PHLPP2	5.71e-07	135	159	7	ae2d3a42e567b5bade304c0caa497eb725be3565
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ADCY4 SLF1 TEK STXBP1 HMCN1 UBR5 SYNE2 MACF1	6.33e-07	200	159	8	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 THSD7A TEK CMIP HMCN1 MEGF6 PTPRR	2.57e-06	169	159	7	58136b8a0bf2dab45c91a053ef7225ea49ccb871
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 THSD7A TEK CMIP HMCN1 MEGF6 PTPRR	2.57e-06	169	159	7	04c6ed38e1d1befba5ef5f37a3c1e045a0b163d6
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDR64 THSD7A ASIC2 CDHR1 PKHD1L1 KCNJ8 RCN3	4.05e-06	181	159	7	b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDR64 THSD7A ASIC2 CDHR1 PKHD1L1 KCNJ8 RCN3	4.05e-06	181	159	7	cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	WDR64 THSD7A ASIC2 CDHR1 PKHD1L1 KCNJ8 RCN3	4.05e-06	181	159	7	ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A CDHR1 PKHD1L1 HMCN1 MEGF6 FMN1 ROBO3	4.35e-06	183	159	7	919c9861073d12fd12aecd7469b1478b13838c43
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 THSD7A TEK CMIP HMCN1 MEGF6 PTPRR	4.35e-06	183	159	7	fc9a7ba148c22d0c8a46f6bc56c772929ac496f7
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 APOB LRP1B PKHD1L1 FAT1 HMCN1 SDK1	4.51e-06	184	159	7	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 APOB LRP1B PKHD1L1 FAT1 HMCN1 SDK1	4.51e-06	184	159	7	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 APOB LRP1B PKHD1L1 FAT1 HMCN1 SDK1	4.51e-06	184	159	7	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	wk_20-22-Epithelial-PNS-intermediate_Schwann\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	THSD7A AATK PPP1R1C KIAA1755 PYGL ABHD12 MED13	4.51e-06	184	159	7	4e3ba64692868563a579902aa9c6f88cab5bce26
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	ADCY4 THSD7A ASIC2 TEK PKHD1L1 SULF2 MPP7	4.67e-06	185	159	7	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	ADCY4 THSD7A ASIC2 TEK PKHD1L1 SULF2 MPP7	4.67e-06	185	159	7	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	Control-Endothelial-Endothelial-Vein\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HDAC9 ADCY4 KLHL1 TEK LRP1B SULF2 HMCN1	4.84e-06	186	159	7	92092f11ecce22c14f244e42c499af0822977e6f
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	HIPK1 DOCK10 RLF SYNE2 MACF1 MED13 DYNC1H1	5.19e-06	188	159	7	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	CDH23 TEK PKHD1L1 CMIP SULF2 PTPRR SYNE2	5.76e-06	191	159	7	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	ADCY4 CDH23 TEK PKHD1L1 SULF2 PTPRR SYNE2	5.96e-06	192	159	7	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	RV-10._Endothelium_II\|World / Chamber and Cluster_Paper	THSD7A TEK PKHD1L1 CMIP SULF2 HMCN1 SYNE2	6.17e-06	193	159	7	2531266bc57339d4e2b22a88817008e32b8c1598
ToppCell	15-Airway-Mesenchymal-Pericyte\|Airway / Age, Tissue, Lineage and Cell class	MTHFD2 IRAG1 ADARB1 HMCN1 MEGF6 DMPK CAP2	6.38e-06	194	159	7	5c1218d239c88082496924653ed2a092dc44a906
ToppCell	COPD-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	USP36 HDAC9 ADAMTS3 MTHFD2 CMIP SYNE2 NLK	6.38e-06	194	159	7	8dcde77767b23e75360adb316cdccf56a00e3726
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAT3 LRP1B TTBK1 HMCN1 PLIN5 CNTN3 PYGL	6.60e-06	195	159	7	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	FAT3 LRP1B TTBK1 HMCN1 PLIN5 CNTN3 PYGL	6.60e-06	195	159	7	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	HDAC9 ADCY4 CDH23 TEK PKHD1L1 SULF2 PTPRR	7.53e-06	199	159	7	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Vein\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	HDAC9 ADCY4 KLHL1 TEK CMIP HMCN1 SYNE2	7.78e-06	200	159	7	7eb366b2c5394af7c77650bde6261e7dac67154e
ToppCell	TCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Papillary_Carcinoma\|TCGA-Breast / Sample_Type by Project: Shred V9	HEATR6 INTS2 KCNF1 CCDC47 USP32 MED13	9.94e-06	137	159	6	2a5d2a99a2c532480d00b80a4885514a8a5c80fa
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	THSD7A MBOAT1 ADAMTS3 M1AP ROBO3 SDK1	1.49e-05	147	159	6	64fa0753a3a79f492ef8acc6942bf90d379a983f
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR64 FAT3 LRP1B PKHD1L1 HMCN1 CNTN3	2.40e-05	160	159	6	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FAT3 PCDHB14 DOCK10 IRAG1 EGFLAM SDK1	2.40e-05	160	159	6	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	WDR64 FAT3 LRP1B PKHD1L1 HMCN1 CNTN3	2.40e-05	160	159	6	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CAND2 DUSP15 CAMTA2 CNTN3 DMPK WNK2	3.05e-05	167	159	6	d1a13d6ada572d8ddb2da95e6e122d2b705fad7f
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)\|Striatum / BrainAtlas - Mouse McCarroll V32	SLF1 SYT9 RWDD3 METTL4 ARHGEF11 CCDC47	3.26e-05	169	159	6	c3bf0cb67f200d02d5a021754e9b2a68d23ea168
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)--\|Striatum / BrainAtlas - Mouse McCarroll V32	SLF1 SYT9 RWDD3 METTL4 ARHGEF11 CCDC47	3.26e-05	169	159	6	5375eb52ebadccb7bfff997a11985f23e81014d6
ToppCell	Striatum-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Excitatory_Neuron.Gad1Gad2.Sgol2a_(Very_small_cluster)-\|Striatum / BrainAtlas - Mouse McCarroll V32	SLF1 SYT9 RWDD3 METTL4 ARHGEF11 CCDC47	3.26e-05	169	159	6	1c132d21255f5a5174ac38db4e91927f9093418e
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MYCBP2 DOCK10 SULF2 AATK PYGL ABHD12	3.48e-05	171	159	6	845f312f8cbe29d820da25f0e6d75deb382bbfd8
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	USP36 HIPK1 APOB SYNE2 NLRC5 MACF1	3.48e-05	171	159	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 DOCK10 IRAG1 PTPRR CNTN3 PYGL	3.60e-05	172	159	6	08a3fe536b1b064c5ee7779bc2b1115a5963a26b
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 DOCK10 IRAG1 PTPRR CNTN3 PYGL	3.60e-05	172	159	6	553701349444eb366df3c11f54bb093434f153c6
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THSD7A LRCH2 GDF3 PKHD1L1 KCNF1 PLIN5	3.72e-05	173	159	6	7dc988fc0ba29990567bf1bcdeb3faeeee507eb1
ToppCell	facs-Lung-3m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	THSD7A PKHD1L1 CMIP PTPRR ROBO3 RCN3	4.36e-05	178	159	6	9f59a9af232d77bb55603a7776dbf9749ea652f2
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADAMTS3 ASIC2 EVC FAT1 SYNE2 SDK1	4.36e-05	178	159	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EPYC FAT3 FAT1 EGFLAM CDH15 RCN3	4.36e-05	178	159	6	e32f5ed7a492edfa7073416008b1fcfae6b854ad
ToppCell	COPD-Endothelial-VE_Venous\|Endothelial / Disease state, Lineage and Cell class	HDAC9 CDH23 TEK CMIP ARSB PTPRR	4.50e-05	179	159	6	e816dd846a6918ec143b57a380c3a47ed073b66e
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	APOB IRAG1 HMCN1 KIAA1755 CNTN3 CAP2	4.78e-05	181	159	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DNAH2 DOCK10 CDH23 LCP2 FAT1 MN1	4.78e-05	181	159	6	8fd64404e57c22c204d835fc5626f73554257b19
ToppCell	droplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAMTS3 TTBK1 PTPRR TET1 KIAA1755 SDK1	4.78e-05	181	159	6	7af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-2\|TCGA-Skin / Sample_Type by Project: Shred V9	NPC1 HEATR6 FMN1 USP32 DYNC1H1 CAP2	4.78e-05	181	159	6	9d5b331cabc5524f0a9fd8b571e87be4c447c7d4
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C16orf74 CDH23 RXRA FAT2 PTPRR WNK2	4.93e-05	182	159	6	678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	C16orf74 CDH23 RXRA FAT2 PTPRR WNK2	4.93e-05	182	159	6	8d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 WDR64 SULF2 HMCN1 KCNF1 KIF17	4.93e-05	182	159	6	f231e86524b628e6e11ac33d5c34be99d454a92a
ToppCell	Endothelial-E\|World / shred on cell class and cell subclass (v4)	ADCY4 THSD7A TEK CMIP MEGF6 PTPRR	5.24e-05	184	159	6	b4c561924c508536fd2112e91e32176b95fdf63a
ToppCell	droplet-Lung-nan-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NPC1 DOCK10 ADARB1 RXRA SULF2 ABHD12	5.24e-05	184	159	6	3261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADCY4 TEK PKHD1L1 SULF2 PLIN5 MPP7	5.40e-05	185	159	6	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LAMB4 KLHL1 LRP1B RXRA CMIP FAM186A	5.56e-05	186	159	6	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	ADCY4 TEK PKHD1L1 CMIP SULF2 HMCN1	5.73e-05	187	159	6	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	Pericytes-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	CAND2 IRAG1 ADARB1 KIAA1755 EGFLAM DMPK	5.73e-05	187	159	6	35f25780d113f60bf4c13749013c09612ee4ff41
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Dcn\|Hippocampus / BrainAtlas - Mouse McCarroll V32	EPYC APOB PKHD1L1 ADAD2	5.88e-05	59	159	4	ebc80c32b56e97c3ab3ac5ae00f06f7f2bcc3d39
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Dcn-Excitatory_Neuron.Slc17a7.Dcn-Camk2d_(CA1_Principal_cells)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	EPYC APOB PKHD1L1 ADAD2	5.88e-05	59	159	4	719728ed089762ae79cbfbe56c4171d70361a772
ToppCell	Hippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Dcn-Excitatory_Neuron.Slc17a7.Dcn-Camk2d_(CA1_Principal_cells)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	EPYC APOB PKHD1L1 ADAD2	5.88e-05	59	159	4	55954d610f5a813ef15ab5e898c5ad309fc9e319
ToppCell	P03-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADCY4 TEK CMIP HMCN1 MEGF6 PTPRR	5.90e-05	188	159	6	5eb107122064f0a99dfd445cc87d3766f7257216
ToppCell	COVID-19-lung-Vein_EC\|lung / Disease (COVID-19 only), tissue and cell type	HDAC9 ADCY4 THSD7A TEK PKHD1L1 SULF2	5.90e-05	188	159	6	d582b76fc2faac526c9bf97503041129e1a6a211
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK10 ADARB1 RXRA SULF2 PYGL ABHD12	6.08e-05	189	159	6	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A LRCH2 PCDHB14 EVC FAT1 DMPK	6.08e-05	189	159	6	1db5dd1ef2a65251af2d5696622d1dd9c4ae2b55
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A LRCH2 PCDHB14 EVC FAT1 DMPK	6.08e-05	189	159	6	bfb1c183a8a2752a2368b74150e66181c6a9da48
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	THSD7A TEK PKHD1L1 CMIP SULF2 HMCN1	6.08e-05	189	159	6	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	THSD7A TEK PKHD1L1 CMIP SULF2 HMCN1	6.08e-05	189	159	6	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADCY4 TEK PKHD1L1 SULF2 PLIN5 MPP7	6.08e-05	189	159	6	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	facs-Thymus-Epithelium-3m-Mesenchymal-fibroblast\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	THSD7A LRCH2 PCDHB14 EVC FAT1 DMPK	6.08e-05	189	159	6	14833feea8f80744a06ece73f813eaeff8c4dd61
ToppCell	T_cells-GZMK+_CD8+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	SLF1 LCP2 ADARB1 SYNE2 NLRC5 MACF1	6.08e-05	189	159	6	e2ca075aedf7c370ab4ede6272254ffd06cbcdec
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADCY4 THSD7A TEK CMIP MEGF6 PTPRR	6.26e-05	190	159	6	e1b721bb74561fe51c53328a0394c9954e489049
ToppCell	normal_Lung-Endothelial_cells-Lymphatic_ECs\|normal_Lung / Location, Cell class and cell subclass	ADCY4 THSD7A GDF3 PKHD1L1 PLIN5 MPP7	6.26e-05	190	159	6	2185db6007404a2b22325f91460dd17635be9bba
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK10 ADARB1 RXRA SULF2 PYGL ABHD12	6.26e-05	190	159	6	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	wk_20-22-Endothelial-Lymph_endothelial-Intermediate_lymphatic_endo\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	ADCY4 GDF3 PKHD1L1 SULF2 PLIN5 MPP7	6.26e-05	190	159	6	103e78c2233c3ee0c215a9dafe70705477e9ee5e
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 THSD7A TEK HMCN1 MEGF6 PTPRR	6.26e-05	190	159	6	9b0ad888eb20acc011904d8593bc32bdef18d050
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 TEK GDF3 PKHD1L1 SULF2 ROBO3	6.26e-05	190	159	6	6b704deeb44e1ffa10e604d0e5612b022f6cd9a6
ToppCell	P03-Endothelial-large_vessel_endothelial_cell\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ADCY4 THSD7A TEK HMCN1 MEGF6 PTPRR	6.44e-05	191	159	6	b680e0c35f1004be36f9f0680ae3c62952e2b607
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	THSD7A TEK PKHD1L1 CMIP SULF2 HMCN1	6.63e-05	192	159	6	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	COVID-19-kidney-AQP1+PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ADCY4 THSD7A TEK SULF2 SYNE2 MN1	6.63e-05	192	159	6	27ff3621e177e7932dd44dd6baa81551ea75a874
ToppCell	LPS_only-Endothelial-Endothelial-Vein\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HDAC9 ADCY4 KLHL1 TEK LRP1B HMCN1	6.63e-05	192	159	6	52acaecd3703166f5ce3b328aff7c82bd142fee4
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Vein\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HDAC9 ADCY4 KLHL1 TEK LRP1B HMCN1	6.63e-05	192	159	6	81baf1c4063469bb0c03a8602b40e387ba7b0dfb
ToppCell	PND10-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 THSD7A TEK HMCN1 MEGF6 PTPRR	6.63e-05	192	159	6	c157981b9a179925edcaabc0cb3b8805f0929004
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF609 CMIP SYNE2 MACF1 AKAP13 SDK1	6.63e-05	192	159	6	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	THSD7A TEK PKHD1L1 CMIP SULF2 HMCN1	6.83e-05	193	159	6	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT3 CDH23 ADARB1 HMCN1 MACF1 SDK1	6.83e-05	193	159	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10\|TCGA-Colorectal / Sample_Type by Project: Shred V9	THSD7A PCDHB5 EVC TEK HMCN1 MN1	6.83e-05	193	159	6	194e7fa00a50cc4e026987b715323d125d79594e
ToppCell	PND03-Endothelial-Endothelial_blood-vessel-Macrovascular_EC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ADCY4 THSD7A TEK HMCN1 MEGF6 PTPRR	6.83e-05	193	159	6	58c590dd6f21bc7ae58ae1729dd574c0f1069592
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Vein\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HDAC9 ADCY4 KLHL1 TEK LRP1B HMCN1	6.83e-05	193	159	6	7261c1ce30c796b61c6ec58e64a051baa24732ff
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	ADCY4 TEK PKHD1L1 CMIP SULF2 HMCN1	7.02e-05	194	159	6	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SLF1 THSD7A TEK STXBP1 HMCN1 MACF1	7.02e-05	194	159	6	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Monocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HDAC9 DOCK10 CDH23 LCP2 BID NOD2	7.02e-05	194	159	6	badefcec2af86cbcd97305f4843e84db0f3ebc66
ToppCell	Adult-Immune-monocyte-D231\|Adult / Lineage, Cell type, age group and donor	HDAC9 DOCK10 CDH23 LCP2 BID SULF2	7.22e-05	195	159	6	ea24da6fea1487acb1e56c28c0649858cc0a12bd
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	APOB NSUN6 SYNE2 NLRC5 MACF1	7.39e-05	121	159	5	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	HDAC9 DOCK10 LCP2 NOD2 SULF2 FMN1	7.43e-05	196	159	6	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	10x5'v1-week_12-13-Mesenchymal_osteo-stroma-early_osteoblast\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	EPYC FAT3 FAT1 EGFLAM CDH15 RCN3	7.64e-05	197	159	6	2ca5ebb708935a90b12b8e98a22ae2d664ed002e
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADCY4 TEK ADARB1 SULF2 PHLPP1 MN1	7.64e-05	197	159	6	cd509e49bbdbf991cc5913960ff3ef275ad40628
Disease	phospholipids:total lipids ratio, high density lipoprotein cholesterol measurement	ASIC2 APOB CMIP SULF2 GFOD2 NLRC5 MACF1 CDH15 HDLBP	3.79e-05	307	155	9	EFO_0004612, EFO_0020946
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	KDM5C TEK LRP1B PEBP1 SYNE2 AKAP13	1.36e-04	148	155	6	C0279702
Disease	obesity (implicated_via_orthology)	KDM3A ADARB1 PNPLA5 PLIN5 PUM1 SDK1 MED13	1.48e-04	215	155	7	DOID:9970 (implicated_via_orthology)
Disease	Photosensitive Trichothiodystrophy	ERCC2 ERCC3	1.63e-04	4	155	2	C1866504
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	OPA3 APOB CMIP SYNE2 MACF1	2.17e-04	103	155	5	EFO_0008595, EFO_0020944
Disease	Endometrial Stromal Sarcoma	NUTM2A NUTM2B	2.71e-04	5	155	2	C0206630
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	4.06e-04	6	155	2	C0334488
Disease	stearoyl sphingomyelin (d18:1/18:0) measurement	CAMTA2 SYNE2	4.06e-04	6	155	2	EFO_0800611
Disease	childhood onset asthma, age at onset, environmental tobacco smoke exposure measurement	KLHL1 PYGL	4.06e-04	6	155	2	EFO_0004847, EFO_0008361, MONDO_0005405
Disease	xeroderma pigmentosum (is_implicated_in)	ERCC2 ERCC3	4.06e-04	6	155	2	DOID:0050427 (is_implicated_in)
Disease	xeroderma pigmentosum (implicated_via_orthology)	ERCC2 ERCC3	4.06e-04	6	155	2	DOID:0050427 (implicated_via_orthology)
Disease	asphyxia neonatorum (biomarker_via_orthology)	ERCC2 ERCC3	4.06e-04	6	155	2	DOID:11088 (biomarker_via_orthology)
Disease	Trichothiodystrophy Syndromes	ERCC2 ERCC3	4.06e-04	6	155	2	C1955934
Disease	Cockayne syndrome (implicated_via_orthology)	ERCC2 ERCC3	4.06e-04	6	155	2	DOID:2962 (implicated_via_orthology)
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	OPA3 APOB CMIP SYNE2 MACF1	4.57e-04	121	155	5	EFO_0008595, EFO_0020943
Disease	sleep duration, high density lipoprotein cholesterol measurement	TMEM94 APOB CMIP NLRC5 MACF1	4.57e-04	121	155	5	EFO_0004612, EFO_0005271
Disease	Sarcomatoid Renal Cell Carcinoma	KDM5C LRP1B PEBP1 SYNE2 AKAP13	5.90e-04	128	155	5	C1266043
Disease	Chromophobe Renal Cell Carcinoma	KDM5C LRP1B PEBP1 SYNE2 AKAP13	5.90e-04	128	155	5	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	KDM5C LRP1B PEBP1 SYNE2 AKAP13	5.90e-04	128	155	5	C1266044
Disease	Papillary Renal Cell Carcinoma	KDM5C LRP1B PEBP1 SYNE2 AKAP13	5.90e-04	128	155	5	C1306837
Disease	Renal Cell Carcinoma	KDM5C LRP1B PEBP1 SYNE2 AKAP13	5.90e-04	128	155	5	C0007134
Disease	Global developmental delay	TMEM94 KDM5C CCDC47 PUM1 MN1	7.02e-04	133	155	5	C0557874
Disease	free cholesterol in large HDL measurement	APOB CMIP SULF2 NLRC5	8.10e-04	79	155	4	EFO_0022157
Disease	Xeroderma pigmentosum	ERCC2 ERCC3	9.63e-04	9	155	2	cv:C0043346
Disease	Abnormality of the face	PUM1 MN1	9.63e-04	9	155	2	C4025871
Disease	cortical surface area measurement, neuroimaging measurement	HDAC9 SLF1 ADAMTS3 FAT3 MEGF6 KIAA1755	1.31e-03	227	155	6	EFO_0004346, EFO_0010736
Disease	Basal cell carcinoma	ERCC2 ERCC3	1.46e-03	11	155	2	C0007117
Disease	Tremor	CYP2D6 ABHD12	1.46e-03	11	155	2	C0040822
Disease	Occupational Diseases	ERCC2 CYP2D6	1.46e-03	11	155	2	C0028797
Disease	ceramide measurement	HDAC9 POLR1A APOB SYNE2 KIF17 SDK1	1.56e-03	235	155	6	EFO_0010222
Disease	S-warfarin measurement	MAN2B2 LRP1B FMN1 CNTN3	1.74e-03	97	155	4	EFO_0803323
Disease	hearing impairment	CDH23 ARSB MN1 ABHD12	1.80e-03	98	155	4	C1384666
Disease	triacylglycerol 54:4 measurement	APOB LRCH3 SDK1	1.83e-03	46	155	3	EFO_0010422
Disease	gallbladder cancer (is_implicated_in)	APOB LRP1B	2.06e-03	13	155	2	DOID:3121 (is_implicated_in)
Disease	cardioembolic stroke	DOCK10 TEK TTBK1 SYNE2 KIAA1755	2.09e-03	170	155	5	EFO_1001976
Disease	high density lipoprotein particle size measurement	APOB CMIP SULF2 NLRC5 HDLBP	2.09e-03	170	155	5	EFO_0008592
Disease	lipoprotein measurement	APOB CMIP SULF2 NLRC5	2.32e-03	105	155	4	EFO_0004732
Disease	cholesteryl esters to total lipids in IDL percentage	APOB CMIP MACF1	2.33e-03	50	155	3	EFO_0022247
Disease	thalamus volume change measurement	ASIC2 FAT1	2.39e-03	14	155	2	EFO_0021496
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	ADAMTS3 APOB	2.39e-03	14	155	2	EFO_0004611, EFO_0008589
Disease	Intellectual Disability	TMEM94 KDM5C CCDC47 MACF1 PUM1 MN1 MED13 DYNC1H1	2.59e-03	447	155	8	C3714756
Disease	hair morphology measurement	SLF1 THSD7A RPTOR	2.90e-03	54	155	3	EFO_0007821
Disease	triglycerides to total lipids in medium HDL percentage	APOB CMIP NLRC5	3.21e-03	56	155	3	EFO_0022333
Disease	cholesteryl esters to total lipids in medium HDL percentage	APOB CMIP NLRC5	3.21e-03	56	155	3	EFO_0022251
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	NPC1 POLR1A ADARB1 SULF2 RPTOR TET1 MACF1	3.22e-03	364	155	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	facial pigmentation measurement	CCDC59 FMN1 PPP1R1C	3.38e-03	57	155	3	EFO_0006942
Disease	colon cancer (is_marker_for)	KDM5C UBR5 PIK3R2	3.73e-03	59	155	3	DOID:219 (is_marker_for)
Disease	cholesterol in medium HDL measurement	APOB CMIP NLRC5	3.73e-03	59	155	3	EFO_0021903
Disease	triglycerides to total lipids in large HDL percentage	APOB CMIP NLRC5	3.91e-03	60	155	3	EFO_0022330
Disease	cholesterol to total lipids in IDL percentage	APOB CMIP MACF1	3.91e-03	60	155	3	EFO_0022233
Disease	cholesterol to total lipids in medium HDL percentage	APOB CMIP NLRC5	3.91e-03	60	155	3	EFO_0022237
Disease	free cholesterol in HDL measurement	APOB CMIP NLRC5	4.09e-03	61	155	3	EFO_0022264
Disease	neuroimaging measurement	HDAC9 ADAMTS3 RBBP5 FAT3 METTL4 IRAG1 ARHGEF11 SULF2 KIAA1755 MACF1 ROBO3 ABHD12 WNK2	4.32e-03	1069	155	13	EFO_0004346
Disease	diet measurement, HOMA-B	KLHL1 FAT3	4.42e-03	19	155	2	EFO_0004469, EFO_0008111
Disease	response to methotrexate, neurotoxicity	MBOAT1 MACF1	4.42e-03	19	155	2	EFO_0011057, GO_0031427
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	APOB CMIP SULF2 SYNE2 NLRC5 MACF1	4.49e-03	291	155	6	EFO_0008317, EFO_0020946
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	APOB CMIP SYNE2 MACF1	4.59e-03	127	155	4	EFO_0008595, EFO_0020947
Disease	PR interval	HDAC9 MYCBP2 ASIC2 METTL4 FAT1 SYNE2 KIAA1755 MACF1	4.78e-03	495	155	8	EFO_0004462
Disease	lobe attachment	HDAC9 HMCN1 FMN1 SHPRH MN1	4.84e-03	207	155	5	EFO_0007667
Disease	total lipids in very large HDL measurement	APOB CMIP NLRC5	5.11e-03	66	155	3	EFO_0022312

Protein segments in the cluster

Peptide	Gene	Start	Entry
PLAPLSVENILTHEQ	ADAD2	196	Q8NCV1
EVFITLLDVNDHPPQ	CDHR1	561	Q96JP9
LQEQLHSVPLSRDIP	EGFLAM	81	Q63HQ2
PIEDGVNLSLEHLQP	GCLM	131	P48507
EAQIDDEAHPVLLQP	AKAP13	1176	Q12802
DEAHPVLLQPVAKEL	AKAP13	1181	Q12802
ARLFPNLPELIEIHN	ARHGEF11	776	O15085
EHENIIVAIAPLLEN	CMIP	221	Q8IY22
DPLLPSVAQAVQHLQ	C1orf216	141	Q8TAB5
LQNPDIVLVHYLNVP	CAMTA2	136	O94983
LIPENRAHLSPEVQL	BRPF3	731	Q9ULD4
LLENVLPAHVAPQFI	ADCY4	841	Q8NFM4
PPSVQEEHGQLLALL	DHX30	1161	Q7L2E3
HILQVTILDINDNPP	CDH23	1511	Q9H251
QLVPPQTDVLLHIDV	ALG12	381	Q9BV10
LLDVNLQIPDPHLAD	ASIC2	116	Q16515
LPPAQDQPLVEANHL	RCN3	271	Q96D15
PCILHFQLLLENPVQ	PCDHB5	101	Q9Y5E4
LDKPEQFLHELAQIP	FMN1	1121	Q68DA7
LILHAEDDPVVPFQL	ABHD12	326	Q8N2K0
RLLHVVVVDANDNPP	FAT1	806	Q14517
HPELVEGLVLINVDP	NDRG3	151	Q9UGV2
NHLVHLPEELAELPL	LRCH3	206	Q96II8
GLQLPQEIPFHELQL	MAP3K10	86	Q02779
TVLATDPLLHQDPVQ	OAZ3	106	Q9UMX2
VPIHQLDIPVDNPIE	KCNJ8	241	Q15842
IDLELHNPKAIAVDP	LRP1B	321	Q9NZR2
QIDQQPPRLLIVHIA	M1AP	16	Q8TC57
LPQEQIQAELSPAHD	NUDT22	16	Q9BRQ3
INPVPVDLHEQQLSL	NADK2	231	Q4G0N4
DQGLLLPAPAVEHIV	HIPK1	71	Q86Z02
DEVVVHLAPLNPLLL	KIAA1755	86	Q5JYT7
LQEEPPLVIINVFDH	FER1L4	826	A9Z1Z3
PELELALFLVQEPHV	GDF3	141	Q9NR23
NKDPITIVDVPAHLQ	CCDC47	116	Q96A33
QQPHENDVAALLKPI	CAP2	96	P40123
PAGHIIDLVNDQLPD	IRAG1	126	Q9Y6F6
DNNLDHIPLPLPENL	EPYC	246	Q99645
LEQLLIHQPEDPIPF	AK8	31	Q96MA6
VEVIVLDVNENLHPP	FAT2	1016	Q9NYQ8
LALEALQAQVQAAPP	OPA3	131	Q9H6K4
IPPNAAALEAAQDLI	PGLYRP4	316	Q96LB8
PLSLQEVDEQPQHPL	PEBP1	11	P30086
HICLDFIPELIAQPE	INTS2	1036	Q9H0H0
ELLAALPAQLQPHVD	MPP7	16	Q5T2T1
LPAQLQPHVDSQEDL	MPP7	21	Q5T2T1
STHAPLPEVQLLLQQ	HEATR6	591	Q6AI08
PELIVHPVLDSPNAV	NAXD	121	Q8IW45
TDAHLANPVLPDEVL	ERCC2	301	P18074
IPVQALLHLRHPEAE	GNL1	451	P36915
DPQLPLNLAALQAHV	METTL25B	386	Q96FB5
IHSQEEPPIIDQLGL	ASIC3	241	Q9UHC3
APETEPIDVAAHLQL	HMGXB4	516	Q9UGU5
NVLSALDILQPPHID	NLK	196	Q9UBE8
ILQHPDLQDVLLIPV	NSUN6	86	Q8TEA1
PSEGLQLHLPQVLAD	ADARB1	311	P78563
EHPLLEQVELPAVAS	PHC3	631	Q8NDX5
EQLLEPHVQAPSLEP	DMPK	426	Q09013
DQVVLNIVEVLPHLP	NLRC5	756	Q86WI3
ALIAQLPSPAIDHEQ	MACF1	5801	Q9UPN3
NIELQGVPNDEVHPL	RBBP5	456	Q15291
ELHVILNNPILLPCE	HMCN1	3996	Q96RW7
NQEIHLSPITLQPAL	PTPRR	266	Q15256
QRILEHCLPDQTLPI	PUM1	1011	Q14671
FGPPLDIQILHQVLD	NPC1	431	O15118
LHIQVIVLDANDNPP	PCDHGA3	226	Q9Y5H0
LEQPNIVHDLPAAVL	PSMG1	206	O95456
KLLQEHLEEQEVAPP	PIK3R2	286	O00459
PCVLHFQVVLENPLQ	PCDHB14	101	Q9Y5E9
HILQTPIEIIQADSP	OTUD6B	236	Q8N6M0
LNLNDFQVPDLHIPE	APOB	2726	P04114
LHDPVIVLIIPQEND	ADAMTS3	801	O15072
FALHAIDQINPPLNV	IL5RA	231	Q01344
AELEIANPPELQKHL	KDM3A	426	Q9Y4C1
ELPHPLLQQTEDQFL	E2F2	376	Q14209
SLDIAVDNVPLEHPN	DOCK10	616	Q96BY6
REVLNAVPVLLHIPA	CYP2D6	221	P10635
IISIHESPQPLLQDI	DUSP15	31	Q9H1R2
NIHLILEDVNDNPPV	FAT3	3116	Q8TDW7
LLHQDVDLVCISIPP	GFOD2	61	Q3B7J2
DPALVDVLDQPLHTL	IFNL2	116	Q8IZJ0
ELDALGHELPVLAPQ	BID	36	P55957
HPLSELLGIPLDQVN	MBOAT1	21	Q6ZNC8
QEAVTLPPNLHLQIL	MAN2B2	866	Q9Y2E5
ENLGLVAEPQAHAPI	MAPKBP1	1266	O60336
LALQSVHEPLQVPEE	ARSB	236	P15848
LQQNIEIPEISLPIH	DYNC1H1	196	Q14204
VLDIHLPIPSQNLTD	LAMB4	1506	A4D0S4
PVLNDKHLDVPDIII	C16orf74	26	Q96GX8
ENLKQAVLPHQPVEA	EVC	141	P57679
HPDVIQHLLQDPVIR	ERCC3	181	P19447
IHELNLSQPIPLIIE	FAM186A	2236	A6NE01
ELEPLAEDILHQSPN	HDAC9	976	Q9UKV0
EAPLALQLQPQASLH	DZANK1	271	Q9NVP4
PLQLDLQPILAEALH	CAND2	641	O75155
LDKLVEQLQVEDPHP	DNAH2	3906	Q9P225
RLEVIELPHSPQNLL	SDK1	661	Q7Z5N4
IPHFSELPLDDQVIL	RXRA	286	P19793
IEILEVNDHAPVLAP	CDH15	471	P55291
SVILPCQVQHDPLLD	CNTN3	516	Q9P232
ADVNVLPIPDHKLIV	METTL4	396	Q8N3J2
HLQVIILDNNPLQVP	LRCH2	271	Q5VUJ6
KLLPQPVIQHDVEAE	KIF17	391	Q9P2E2
PPDEIHPLEILQAQI	MN1	1146	Q10571
LPHIAVLQDELPQLF	MEGF6	471	O75095
AVIHPQFLEELLSPD	NUTM2A	581	Q8IVF1
AVIHPQFLEELLSPD	NUTM2B	581	A6NNL0
AVIHPQFLEELLSPD	NUTM2E	581	B1AL46
DVPPENIDQIHLSIA	SYT9	426	Q86SS6
VLEPLAASINPLNDH	TAF6L	246	Q9Y6J9
LLINIIPEDHIPLNL	POLR1A	691	O95602
RPVIIQELENQHLCP	THSD7A	1446	Q9UPZ6
PPALQDIKELQHDVQ	SYNE2	5426	Q8WXH0
QPEQRPTAEEVHLLL	AATK	381	Q6ZMQ8
VDGLLVQLPLPEHID	MTHFD2	126	P13995
APIEHVKQQLQDALP	PNPLA5	91	Q7Z6Z6
VKQQLQDALPPDAHV	PNPLA5	96	Q7Z6Z6
VDIDVEPPLHQALVL	FBXL15	271	Q9H469
ASLVILNEHNPPEID	PPP1R1C	36	Q8WVI7
LVEPILNPAHELQAI	SHPRH	1601	Q149N8
VDHPLSEQVHQPLLE	CCDC59	111	Q9P031
LLAVPVPGVNIEEHL	MYCBP2	841	O75592
DGEIIPHIPANQEVL	ADSS2	381	P30520
PNVHAFTPLQLQELE	RHOXF2B	136	P0C7M4
LLSTEPHEEVPNILQ	MED13	2046	Q9UHV7
PHEEVPNILQQPLAL	MED13	2051	Q9UHV7
LIQHAQIPPEDSEII	STXBP1	426	P61764
ELEVAAINPNHPLAQ	RPTOR	216	Q8N122
LGVIPQDEQLHVLPL	TET1	1696	Q8NFU7
PHLPDQLVIVNETEA	CLEC16A	946	Q2KHT3
NDIIQLLVRPDPDHL	UHRF2	66	Q96PU4
DVDIPLELVFHLPVN	RWDD3	46	Q9Y3V2
QALAEEDLQHLPPQP	TTBK1	601	Q5TCY1
DVLAALVNQPHLLVP	TRPM5	261	Q9NZQ8
AAFLLQHVQELPVPL	NOD2	196	Q9HC29
QHVQELPVPLALPLE	NOD2	201	Q9HC29
QNLPTLVEHIPLEVL	PHLPP2	561	Q6ZVD8
IHENLTAIPPLIVAE	RLF	1836	Q13129
HLQNIDNVPLLVPLF	TMEM94	961	Q12767
LVHLLNLDQPPSLQD	WDR97	1251	A6NE52
QAVPLAAQRVLHPDE	ROBO3	1306	Q96MS0
PADIVELHDINVEPL	YY2	16	O15391
PIHLLVPVVNNDISS	ZNF609	261	O15014
PNVHAFTPLQLQELE	RHOXF2	136	Q9BQY4
VIFITNPLNEDLQHP	PKHD1L1	3626	Q86WI1
PDILEVHLPHAQPQD	TEK	171	Q02763
IPPVCVLHALLENVL	SLF1	441	Q9BQI6
VLDVQHNQLLELPPN	PHLPP1	966	O60346
PHLEVVPQELGLENS	ZNF18	156	P17022
ALDHAQPLLEHLQPQ	PLIN5	71	Q00G26
IHVPAPELQSDIIAI	HDLBP	1006	Q00341
QPLAETHEAPLAVQP	WNK2	1471	Q9Y3S1
PDQVAIQLNDTHPAL	PYGL	331	P06737
IQLNDTHPALAIPEL	PYGL	336	P06737
LQEIVHQAADPETLP	ZFYVE26	1746	Q68DK2
NPHIVLNIDLAPTIL	SULF2	356	Q8IWU5
PELVTPQDHEVALAN	USP32	1456	Q8NFA0
QVNEDLVSLPHQLPE	USP36	786	Q9P275
EAIPLADQPHLLQPN	UBR5	2046	O95071
NLPEAQPPILVTAHE	WDR64	776	B1ANS9
LPPQILADLENHALF	KLHL1	406	Q9NR64
IREAENIPVHLPNIQ	KDM5C	1006	P41229
IAIALPIHPIINNFV	KCNF1	396	Q9H3M0
INQSLLEPLHLEVDP	KRT77	141	Q7Z794
EDDVHQRPLPQPALL	LCP2	321	Q13094