Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	benzoate-CoA ligase activity	ACSM2A ACSM2B	1.77e-05	3	49	2	GO:0018858
GeneOntologyMolecularFunction	C-acyltransferase activity	ACAT1 ACSM2A ACSM2B	1.79e-05	21	49	3	GO:0016408
GeneOntologyMolecularFunction	decanoate-CoA ligase activity	ACSM2A ACSM2B	3.53e-05	4	49	2	GO:0102391
GeneOntologyMolecularFunction	fatty-acyl-CoA synthase activity	ACSM2A ACSM2B	1.64e-04	8	49	2	GO:0004321
GeneOntologyMolecularFunction	medium-chain fatty acid-CoA ligase activity	ACSM2A ACSM2B	3.20e-04	11	49	2	GO:0031956
GeneOntologyMolecularFunction	translation activator activity	PABPC1 BOLL	6.07e-04	15	49	2	GO:0008494
HumanPheno	Abnormal eating behavior	CACNA1A ARID1B ACAT1 ASH1L DPF2	3.79e-06	128	11	5	HP:0100738
HumanPheno	Oral aversion	ARID1B ACAT1 DPF2	5.01e-06	17	11	3	HP:0012523
Domain	Znf_FYVE_PHD	TRIM66 HGS ASH1L DPF2 BSN	3.32e-05	147	47	5	IPR011011
Domain	-	TRIM66 RNF44 HGS ASH1L DPF2 BSN RNF145	1.21e-04	449	47	7	3.30.40.10
Domain	Znf_RING/FYVE/PHD	TRIM66 RNF44 HGS ASH1L DPF2 BSN RNF145	1.39e-04	459	47	7	IPR013083
Domain	AMP-bd_C	ACSM2A ACSM2B	8.23e-04	17	47	2	IPR025110
Domain	AMP-binding_C	ACSM2A ACSM2B	8.23e-04	17	47	2	PF13193
Domain	PHD	TRIM66 ASH1L DPF2	8.88e-04	75	47	3	PF00628
Domain	Znf_PHD-finger	TRIM66 ASH1L DPF2	1.03e-03	79	47	3	IPR019787
Domain	PHD	TRIM66 ASH1L DPF2	1.46e-03	89	47	3	SM00249
Domain	Znf_PHD	TRIM66 ASH1L DPF2	1.55e-03	91	47	3	IPR001965
Domain	ZF_PHD_2	TRIM66 ASH1L DPF2	1.76e-03	95	47	3	PS50016
Domain	ZF_PHD_1	TRIM66 ASH1L DPF2	1.81e-03	96	47	3	PS01359
Domain	AMP-binding_CS	ACSM2A ACSM2B	1.94e-03	26	47	2	IPR020845
Domain	AMP_BINDING	ACSM2A ACSM2B	2.25e-03	28	47	2	PS00455
Domain	AMP-binding	ACSM2A ACSM2B	2.58e-03	30	47	2	PF00501
Domain	AMP-dep_Synth/Lig	ACSM2A ACSM2B	2.58e-03	30	47	2	IPR000873
Domain	BROMODOMAIN_1	TRIM66 ASH1L	3.90e-03	37	47	2	PS00633
Domain	Bromodomain	TRIM66 ASH1L	4.11e-03	38	47	2	PF00439
Domain	BROMODOMAIN_2	TRIM66 ASH1L	4.77e-03	41	47	2	PS50014
Domain	BROMO	TRIM66 ASH1L	5.01e-03	42	47	2	SM00297
Domain	Bromodomain	TRIM66 ASH1L	5.01e-03	42	47	2	IPR001487
Domain	-	TRIM66 ASH1L	5.01e-03	42	47	2	1.20.920.10
Domain	zf-RING_2	RNF44 RNF145	7.59e-03	52	47	2	PF13639
Domain	Zinc_finger_PHD-type_CS	TRIM66 ASH1L	1.17e-02	65	47	2	IPR019786
Pathway	REACTOME_CONJUGATION_OF_SALICYLATE_WITH_GLYCINE	ACSM2A ACSM2B	1.05e-04	6	38	2	MM14693
Pathway	REACTOME_AMINO_ACID_CONJUGATION	ACSM2A ACSM2B	1.47e-04	7	38	2	MM14598
Pathway	REACTOME_AMINO_ACID_CONJUGATION	ACSM2A ACSM2B	2.52e-04	9	38	2	M26968
Pubmed	The L513S polymorphism in medium-chain acyl-CoA synthetase 2 (MACS2) is associated with risk factors of the metabolic syndrome in a Caucasian study population.	ACSM2A ACSM2B	1.94e-06	2	49	2	16521160
Pubmed	Comparative analyses of disease risk genes belonging to the acyl-CoA synthetase medium-chain (ACSM) family in human liver and cell lines.	ACSM2A ACSM2B	1.94e-06	2	49	2	19634011
Pubmed	Analyses of the genetic diversity and protein expression variation of the acyl: CoA medium-chain ligases, ACSM2A and ACSM2B.	ACSM2A ACSM2B	1.94e-06	2	49	2	29948332
Pubmed	Human transcription factor protein interaction networks.	MRPL4 BCL9L ARID1B HGS ZNF638 PSMD1 DPF2 RAD54L2 LHX8 ATXN1L PABPC1	3.75e-06	1429	49	11	35140242
Pubmed	Expression of Acsm2, a kidney-specific gene, parallels the function and maturation of proximal tubular cells.	ACSM2A ACSM2B	1.16e-05	4	49	2	32830538
Pubmed	The PcG protein hPc2 interacts with the N-terminus of histone demethylase JARID1B and acts as a transcriptional co-repressor.	CACNA1A ONECUT2 ARID1B	1.39e-05	33	49	3	19336002
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	GPD2 FLNA ARID1B CAND1 ACAT1 ASH1L PSMD1 PABPC1	1.58e-05	807	49	8	30575818
Pubmed	Developmental specification of forebrain cholinergic neurons.	GBX1 LHX8	2.91e-05	6	49	2	27847324
Pubmed	Identification of a set of genes showing regionally enriched expression in the mouse brain.	GBX1 LHX8	2.91e-05	6	49	2	18625066
Pubmed	Nuclear import of histone deacetylase 5 by requisite nuclear localization signal phosphorylation.	FLNA CAND1 ACAT1 PSMD1 PABPC1	3.16e-05	258	49	5	21081666
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXM1 RNF44 NR5A2 ZNF638 DPF2 LHX8 RNF145	5.80e-05	709	49	7	22988430
Pubmed	Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation.	HGS PSMD1	6.96e-05	9	49	2	17182860
Pubmed	A genome-wide association study of serum uric acid in African Americans.	ARID1B NR5A2	6.96e-05	9	49	2	21294900
Pubmed	Coffin-Siris Syndrome	ARID1B DPF2	6.96e-05	9	49	2	23556151
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	GPD2 ACAT1 NR5A2 DPF2 RNF145 PABPC1	7.33e-05	503	49	6	36217030
Pubmed	Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated nuclear receptor Ad4BP/SF-1.	NR5A2 RAD54L2	8.69e-05	10	49	2	19692572
Pubmed	The LIM-homeobox gene Lhx8 is required for the development of many cholinergic neurons in the mouse forebrain.	GBX1 LHX8	8.69e-05	10	49	2	12855770
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ARID1B CAND1 RNF44 DAZAP2 AKAP11 BSN	9.67e-05	529	49	6	14621295
Pubmed	DNA damage shifts circadian clock time via Hausp-dependent Cry1 stabilization.	FLNA CAND1 PSMD1 PABPC1	1.10e-04	175	49	4	25756610
Pubmed	Identification of the hypoxia-inducible factor 2α nuclear interactome in melanoma cells reveals master proteins involved in melanoma development.	ARID1B PSMD1 DPF2	1.13e-04	66	49	3	23275444
Pubmed	TIF1γ inhibits lung adenocarcinoma EMT and metastasis by interacting with the TAF15/TBP complex.	FLNA CAND1 PSMD1 PABPC1	1.20e-04	179	49	4	36261009
Pubmed	Multiple roles of integrin-α3 at the neuromuscular junction.	CACNA1A BSN	1.27e-04	12	49	2	28386022
Pubmed	Histogenetic compartments of the mouse centromedial and extended amygdala based on gene expression patterns during development.	GBX1 LHX8	1.27e-04	12	49	2	17990271
Pubmed	MET Inhibitors Promote Liver Tumor Evasion of the Immune Response by Stabilizing PDL1.	GPD2 FLNA PSMD1 PABPC1	1.28e-04	182	49	4	30711629
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	FOXM1 ONECUT2 NR5A2 ASH1L ZNF638 DPF2 LHX8	1.31e-04	808	49	7	20412781
Pubmed	Interaction network of human early embryonic transcription factors.	BCL9L ARID1B DPF2 RAD54L2 ATXN1L	1.35e-04	351	49	5	38297188
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	MRPL4 GPD2 FLNA CAND1 ACAT1 PSMD1 BSN PABPC1 NEK9	1.48e-04	1425	49	9	30948266
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	GPD2 CACNA1A FLNA CAND1 ACAT1 FAM120C CARMIL1 BSN PABPC1	1.53e-04	1431	49	9	37142655
Pubmed	Faciogenital Dysplasia 5 supports cancer stem cell traits in basal-like breast cancer by enhancing EGFR stability.	FLNA ACAT1 PSMD1 PABPC1	1.54e-04	191	49	4	33762435
Pubmed	In vitro nuclear interactome of the HIV-1 Tat protein.	CAND1 ZNF638 DPF2 PABPC1	1.67e-04	195	49	4	19454010
Pubmed	Calcium channels link the muscle-derived synapse organizer laminin β2 to Bassoon and CAST/Erc2 to organize presynaptic active zones.	CACNA1A BSN	1.75e-04	14	49	2	21228161
Pubmed	The mouse homeobox gene Gbx2 is required for the development of cholinergic interneurons in the striatum.	GBX1 LHX8	1.75e-04	14	49	2	21048141
Pubmed	Fyn Regulates Binding Partners of Cyclic-AMP Dependent Protein Kinase A.	CAND1 AKAP11 PABPC1	2.15e-04	82	49	3	30274258
Pubmed	SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.	GPD2 FLNA CAND1 ACAT1 JAGN1 HGS PSMD1	2.18e-04	878	49	7	37223481
Pubmed	A genome-wide association study identifies a novel locus at 6q22.1 associated with ulcerative colitis.	GPD2 BSN	2.30e-04	16	49	2	25082827
Pubmed	A census of human transcription factors: function, expression and evolution.	FOXM1 ONECUT2 NR5A2 ASH1L GBX1 DPF2 LHX8	2.67e-04	908	49	7	19274049
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	FLNA CAND1 PSMD1 BSN PABPC1 NEK9	3.01e-04	653	49	6	33742100
Pubmed	Proteomic analysis of SARS-CoV-2 particles unveils a key role of G3BP proteins in viral assembly.	FLNA PSMD1 PABPC1	3.12e-04	93	49	3	38245532
Pubmed	Robo1 regulates semaphorin signaling to guide the migration of cortical interneurons through the ventral forebrain.	FLT1 LHX8	3.27e-04	19	49	2	21508241
Pubmed	Inactivation of Arx, the murine ortholog of the X-linked lissencephaly with ambiguous genitalia gene, leads to severe disorganization of the ventral telencephalon with impaired neuronal migration and differentiation.	GBX1 LHX8	3.64e-04	20	49	2	17460091
Pubmed	Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy.	HGS PSMD1 PABPC1	3.75e-04	99	49	3	29676259
Pubmed	Ldb1 is essential for development of Nkx2.1 lineage derived GABAergic and cholinergic neurons in the telencephalon.	GBX1 LHX8	4.01e-04	21	49	2	24157949
Pubmed	Onecut1 is essential for horizontal cell genesis and retinal integrity.	ONECUT2 BSN	4.01e-04	21	49	2	23926259
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	NEK4 BCL9L ARID1B HGS DPF2	4.06e-04	446	49	5	24255178
Pubmed	Hypertonicity-responsive ubiquitin ligase RNF183 promotes Na, K-ATPase lysosomal degradation through ubiquitination of its β1 subunit.	FLNA CAND1 HGS PSMD1 NEK9	4.19e-04	449	49	5	31732153
Pubmed	Embryonic temporal-spatial delineation of excitatory spinal V3 interneuron diversity.	ONECUT2 NR5A2	4.41e-04	22	49	2	38160393
Pubmed	The transcription regulator Lmo3 is required for the development of medial ganglionic eminence derived neurons in the external globus pallidus.	LHX8 BSN	4.41e-04	22	49	2	37532091
Pubmed	Transcription Factor VAX1 Regulates the Regional Specification of the Subpallium Through Repressing Gsx2.	GBX1 LHX8	4.41e-04	22	49	2	33821423
Pubmed	FET family fusion oncoproteins target the SWI/SNF chromatin remodeling complex.	ARID1B DPF2	4.83e-04	23	49	2	30962207
Pubmed	Diversity and specialization of mammalian SWI/SNF complexes.	ARID1B DPF2	4.83e-04	23	49	2	8804307
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	FLNA CAND1 ACAT1 FAM120C PSMD1 PABPC1	4.84e-04	714	49	6	28302793
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	CAND1 PSMD1 PABPC1 NEK9	5.26e-04	264	49	4	32814769
Pubmed	Ubiquitin-conjugating enzyme UBE2O regulates cellular clock function by promoting the degradation of the transcription factor BMAL1.	CAND1 PSMD1	5.26e-04	24	49	2	29871923
Pubmed	SWI/SNF chromatin remodeling and cancer.	ARID1B DPF2	5.26e-04	24	49	2	11790558
Pubmed	Reconstitution of a core chromatin remodeling complex from SWI/SNF subunits.	ARID1B DPF2	5.26e-04	24	49	2	10078207
Pubmed	The SWI/SNF chromatin-remodeling factor stimulates repair by human excision nuclease in the mononucleosome core particle.	ARID1B DPF2	5.26e-04	24	49	2	12215535
Pubmed	UM171 Preserves Epigenetic Marks that Are Reduced in Ex Vivo Culture of Human HSCs via Potentiation of the CLR3-KBTBD4 Complex.	FLNA HGS PABPC1 NEK9	5.48e-04	267	49	4	33417871
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	GPD2 FLNA CAND1 ACAT1 ZNF638 PSMD1 PABPC1	5.49e-04	1024	49	7	24711643
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	BCL9L ARID1B DPF2 ATXN1L	5.56e-04	268	49	4	33640491
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FLNA CAND1 ACAT1 ZNF638 PSMD1 DPF2 PABPC1 NEK9	5.60e-04	1353	49	8	29467282
Pubmed	Upstream open reading frames cause widespread reduction of protein expression and are polymorphic among humans.	ACSM2A ACSM2B	5.71e-04	25	49	2	19372376
Pubmed	AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.	FLNA CAND1 ACAT1 HGS PABPC1	5.89e-04	484	49	5	31995728
Pubmed	Exit from G1 and S phase of the cell cycle is regulated by repressor complexes containing HDAC-Rb-hSWI/SNF and Rb-hSWI/SNF.	ARID1B DPF2	6.18e-04	26	49	2	10778858
Pubmed	Glioma tumor suppressor candidate region gene 1 (GLTSCR1) and its paralog GLTSCR1-like form SWI/SNF chromatin remodeling subcomplexes.	ARID1B DPF2	6.67e-04	27	49	2	29374058
Pubmed	Histone-binding of DPF2 mediates its repressive role in myeloid differentiation.	MRPL4 ARID1B DPF2 PABPC1	6.82e-04	283	49	4	28533407
Pubmed	DYRK1A regulates the recruitment of 53BP1 to the sites of DNA damage in part through interaction with RNF169.	ACAT1 AKAP11 RAD54L2	6.90e-04	122	49	3	30773093
Pubmed	An improved smaller biotin ligase for BioID proximity labeling.	ARID1B ASH1L CCDC168	7.06e-04	123	49	3	26912792
Pubmed	REST repression of neuronal genes requires components of the hSWI.SNF complex.	ARID1B DPF2	7.18e-04	28	49	2	12192000
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FOXM1 FLNA CARMIL1 ZNF638 PSMD1 DPF2	7.38e-04	774	49	6	15302935
Pubmed	The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.	FAM120C ZNF638 AKAP11	7.40e-04	125	49	3	29467281
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	GPD2 FLNA CAND1 CARMIL1 ZNF638 PSMD1 PABPC1 NEK9	7.51e-04	1415	49	8	28515276
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	MRPL4 GPD2 ONECUT2 ARID1B CAND1 ZNF638 DPF2	7.60e-04	1082	49	7	38697112
Pubmed	An embryonic stem cell chromatin remodeling complex, esBAF, is essential for embryonic stem cell self-renewal and pluripotency.	ARID1B DPF2	7.71e-04	29	49	2	19279220
Pubmed	Mammalian SWI/SNF collaborates with a polycomb-associated protein to regulate male germline transcription in the mouse.	ARID1B DPF2	8.25e-04	30	49	2	31043422
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	FLNA ARID1B CAND1 DPF2 RAD54L2 ATXN1L PABPC1	8.50e-04	1103	49	7	34189442
Pubmed	Proline-rich sequence recognition: II. Proteomics analysis of Tsg101 ubiquitin-E2-like variant (UEV) interactions.	HGS PABPC1	9.39e-04	32	49	2	19542561
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	FLNA CAND1 CARMIL1 PSMD1 PABPC1	9.46e-04	538	49	5	28524877
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	FOXM1 NEK4 CARMIL1 ST8SIA3	9.91e-04	313	49	4	20800603
Pubmed	An FBXW7-ZEB2 axis links EMT and tumour microenvironment to promote colorectal cancer stem cells and chemoresistance.	FOXM1 NEK9	9.98e-04	33	49	2	30783098
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	CACNA1A BCL9L FLNA ACAT1 FAM120C PSMD1 BSN	1.03e-03	1139	49	7	36417873
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CAND1 FAM120C CARMIL1 ASH1L ZNF638 PSMD1 PNPLA7 NEK9	1.04e-03	1489	49	8	28611215
Pubmed	The progenitor zone of the ventral medial ganglionic eminence requires Nkx2-1 to generate most of the globus pallidus but few neocortical interneurons.	GBX1 LHX8	1.06e-03	34	49	2	20181579
Pubmed	Shotgun sequencing of the human transcriptome with ORF expressed sequence tags.	CACNA1A FLT1 CARMIL1 AKAP11 ATXN1L	1.06e-03	552	49	5	10737800
Pubmed	SPATA2 Links CYLD to LUBAC, Activates CYLD, and Controls LUBAC Signaling.	MRPL4 FLNA ACAT1 PSMD1 PABPC1	1.11e-03	558	49	5	27591049
Pubmed	Quantitative interaction proteomics of neurodegenerative disease proteins.	JAGN1 HGS PSMD1 PABPC1	1.11e-03	323	49	4	25959826
Pubmed	Mettl14-mediated m6A modification ensures the cell-cycle progression of late-born retinal progenitor cells.	FOXM1 BSN	1.12e-03	35	49	2	37269288
Pubmed	The core SWI/SNF catalytic subunit Brg1 regulates nephron progenitor cell proliferation and differentiation.	ARID1B DPF2	1.12e-03	35	49	2	32504627
Pubmed	The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.	GPD2 PSMD1 AKAP11 NEK9	1.14e-03	325	49	4	36168628
Pubmed	Comparative analysis of virus-host interactomes with a mammalian high-throughput protein complementation assay based on Gaussia princeps luciferase.	FOXM1 FLNA DAZAP2	1.21e-03	148	49	3	22898364
Pubmed	Analysis of the SWI/SNF chromatin-remodeling complex during early heart development and BAF250a repression cardiac gene transcription during P19 cell differentiation.	ARID1B DPF2	1.25e-03	37	49	2	24335282
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	FLNA HGS DPF2 RAD54L2 ATXN1L	1.35e-03	583	49	5	29844126
Pubmed	Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.	FLNA HGS BSN PABPC1	1.36e-03	341	49	4	29791485
Pubmed	LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.	FLNA CAND1 PSMD1 PABPC1	1.40e-03	344	49	4	30333137
Interaction	FAM168A interactions	ARID1B HGS DAZAP2 ATXN1L BOLL	1.58e-05	142	45	5	int:FAM168A
Interaction	KLF4 interactions	MRPL4 ARID1B HGS DPF2 PABPC1	2.80e-05	160	45	5	int:KLF4
Interaction	ACSM2A interactions	ACSM2A ACSM2B	2.92e-05	4	45	2	int:ACSM2A
Interaction	ACSM2B interactions	ACSM2A ACSM2B	2.92e-05	4	45	2	int:ACSM2B
Interaction	EGR2 interactions	BCL9L ARID1B DPF2 RAD54L2 ATXN1L	3.85e-05	171	45	5	int:EGR2
Interaction	SOX10 interactions	ARID1B DAZAP2 DPF2 ATXN1L	5.25e-05	92	45	4	int:SOX10
Interaction	AR interactions	BCL9L FLNA ARID1B CAND1 PSMD1 DPF2 RAD54L2 ATXN1L PABPC1 NEK9	5.27e-05	992	45	10	int:AR
Interaction	ALG13 interactions	TRIM66 ARID1B FAM120C ATXN1L PABPC1	5.32e-05	183	45	5	int:ALG13
Interaction	C1orf94 interactions	HGS DAZAP2 ATXN1L BOLL	8.16e-05	103	45	4	int:C1orf94
Interaction	FGD5 interactions	FLNA ACAT1 PSMD1 AKAP11 PABPC1	9.53e-05	207	45	5	int:FGD5
Interaction	TBR1 interactions	BCL9L ARID1B DPF2 ATXN1L	1.17e-04	113	45	4	int:TBR1
Interaction	FAM120A interactions	MRPL4 TRIM66 CAND1 FAM120C DPF2 PABPC1	1.19e-04	349	45	6	int:FAM120A
Interaction	CIMIP2A interactions	NEK4 HGS	1.35e-04	8	45	2	int:CIMIP2A
Cytoband	18q21.31	ONECUT2 ST8SIA3	1.33e-04	16	49	2	18q21.31
Cytoband	16p12.3	ACSM2A ACSM2B	6.13e-04	34	49	2	16p12.3
GeneFamily	PHD finger proteins	TRIM66 ASH1L DPF2	5.84e-04	90	33	3	88
GeneFamily	Acyl-CoA synthetase family	ACSM2A ACSM2B	1.02e-03	26	33	2	40
Disease	X-21319 measurement	ACSM2A ACSM2B	2.48e-06	2	47	2	EFO_0800807
Disease	X-11478 measurement	ACSM2A ACSM2B	7.44e-06	3	47	2	EFO_0021242
Disease	cognitive function measurement, self reported educational attainment	NEK4 GPD2 ARID1B CARMIL1 ZNF638 BSN	2.06e-05	355	47	6	EFO_0004784, EFO_0008354
Disease	3-hydroxyhexanoate measurement	ACSM2A ACSM2B	2.48e-05	5	47	2	EFO_0800378
Disease	indoleacetoylcarnitine measurement	ACSM2A ACSM2B	3.71e-05	6	47	2	EFO_0800106
Disease	cerebellar ataxia (implicated_via_orthology)	CACNA1A PNPLA7	6.91e-05	8	47	2	DOID:0050753 (implicated_via_orthology)
Disease	Coffin-Siris syndrome	ARID1B DPF2	1.92e-04	13	47	2	C0265338
Disease	Schwartz-Jampel Syndrome, Type 1	FLNA FLT1	2.94e-04	16	47	2	C4551479
Disease	Spondyloepiphyseal Dysplasia	FLNA FLT1	2.94e-04	16	47	2	C0038015
Disease	Schwartz-Jampel Syndrome	FLNA FLT1	2.94e-04	16	47	2	C0036391
Disease	Melnick-Needles Syndrome	FLNA FLT1	2.94e-04	16	47	2	C0025237
Disease	Spondyloepiphyseal Dysplasia Tarda, X-Linked	FLNA FLT1	2.94e-04	16	47	2	C3541456
Disease	Van Buchem disease	FLNA FLT1	3.33e-04	17	47	2	C0432272
Disease	Dyschondroplasias	FLNA FLT1	4.17e-04	19	47	2	C0013366
Disease	Osteochondrodysplasias	FLNA FLT1	4.17e-04	19	47	2	C0029422
Disease	attention deficit hyperactivity disorder, autism spectrum disorder, intelligence	NEK4 GPD2 ARID1B ZNF638 BSN	4.19e-04	398	47	5	EFO_0003756, EFO_0003888, EFO_0004337
Disease	Multiple Epiphyseal Dysplasia	FLNA FLT1	4.63e-04	20	47	2	C0026760
Disease	urinary uromodulin measurement	FOXM1 ACSM2A ACSM2B	4.88e-04	96	47	3	EFO_0005663
Disease	Epileptic encephalopathy	CACNA1A FLNA	1.05e-03	30	47	2	C0543888
Disease	reticulocyte measurement	MRPL4 FLNA ACAT1 ASH1L BSN ATXN1L PABPC1	1.31e-03	1053	47	7	EFO_0010700
Disease	Spinocerebellar Ataxia Type 2	CACNA1A ATXN1L	1.35e-03	34	47	2	C0752121
Disease	Spinocerebellar Ataxia Type 1	CACNA1A ATXN1L	1.35e-03	34	47	2	C0752120
Disease	Spinocerebellar Ataxia Type 5	CACNA1A ATXN1L	1.35e-03	34	47	2	C0752123
Disease	Spinocerebellar Ataxia Type 7	CACNA1A ATXN1L	1.35e-03	34	47	2	C0752125
Disease	Spinocerebellar Ataxia Type 6 (disorder)	CACNA1A ATXN1L	1.35e-03	34	47	2	C0752124
Disease	Ataxia, Spinocerebellar	CACNA1A ATXN1L	1.35e-03	34	47	2	C0087012
Disease	Spinocerebellar Ataxia Type 4	CACNA1A ATXN1L	1.43e-03	35	47	2	C0752122

Protein segments in the cluster

Peptide	Gene	Start	Entry
QGPSPGYRMEMSIFY	CACNA1A	1476	O00555
PASLYSRGMRPLFYS	AGBL3	231	Q8NEM8
LSMSTYPSVPPEMAY	ASH1L	1461	Q9NR48
YMAMRGNFSSPQYPS	CDCP2	261	Q5VXM1
IPRSSIMPAAGTMYL	BOLL	116	Q8N9W6
SSYPIKSMMGAPIVY	ACSM2A	301	Q08AH3
SLPPSSCMSGLMYKY	AKAP11	1321	Q9UKA4
LTSPSPMMRSYGGSY	ARID1B	506	Q8NFD5
PMMRSYGGSYPEYSS	ARID1B	511	Q8NFD5
PSNLSRGMSIYPGYM	RAD54L2	1406	Q9Y4B4
MNPSAPSYPMASLYV	PABPC1	1	P11940
MSAAFPGASLYLPMA	DAZAP2	61	Q15038
HIVMPGYYSPESMGL	GPD2	316	P43304
SMAETLVGTPYYMSP	NEK9	206	Q8TD19
SIAPLIYGSMEMFPA	JAGN1	111	Q8N5M9
PSLMYMEPNVRYSAT	ALOXE3	201	Q9BYJ1
DLAPGRMPIYYQMSR	ATXN1L	221	P0C7T5
LRPMVRGGMYRPYAS	BSN	2216	Q9UPA5
GYMDLLRMLTGPVYS	CAND1	771	Q86VP6
MPLLPAALTSSMLYF	PLPPR5	1	Q32ZL2
PPMFMYIRPSTTLAA	OR4S1	251	Q8NGB4
DMASTLIGTPYYMSP	NEK4	161	P51957
YSPYKEMPGMSQSLS	ONECUT2	211	O95948
RLSPPMLEEMAYSAY	LHX8	301	Q68G74
YIYCRPFMTLPMDTT	OR4D6	256	Q8NGJ1
YVRASMSLSGYMPPL	PNPLA7	1056	Q6ZV29
PRSGHLLYTGYPMFM	GBX1	36	Q14549
TYTPMAPGSYLISIK	FLNA	2486	P21333
LYPVSLYSRAMGSMP	FAM120C	921	Q9NX05
MSKYAMPSSTPLYHN	BCL9L	1091	Q86UU0
NSVSERPPYSYMAMI	FOXM1	231	Q08050
NYTLRFMPIPMYDAS	CARMIL1	626	Q5VZK9
IYPPMSILPNTRMYS	CCDC168	1141	Q8NDH2
SPPALATHYMPYGMA	P2RY6	181	Q15077
FYGAIMLMYVSPTPG	OR11H7	251	Q8NGC8
PYTSSPESIMGYSYM	NR5A2	276	O00482
RGPTSYYYMLPMKVR	MRPL4	156	Q9BYD3
AGLYPSSRSMFIPYR	PRR23B	176	Q6ZRT6
PILRRSGMYTVAMAY	PSMD1	576	Q99460
TPKYASPGAPRMYMF	ST8SIA3	41	O43173
MSNVPYVMNRGSTPY	ACAT1	156	P24752
YSVSMSPRVYMPLIN	OR5T2	171	Q8NGG2
SSYPIKSMMGAPIVY	ACSM2B	301	Q68CK6
YPSFLPYFLSMLPMS	RNF44	301	Q7L0R7
AADPSMVSAYMYPAG	HGS	626	O14964
GYHMYCLTPSMSEPP	DPF2	351	Q92785
GMRMRAPEYSTPEIY	FLT1	1116	P17948
YNQPGMRASPGLSMY	TRIM66	1031	O15016
GPMYLEPLSMNRFTT	RNF145	111	Q96MT1
RLPTPSMMNDYYAAS	ZNF638	406	Q14966
SMMNDYYAASPRIFP	ZNF638	411	Q14966