Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	DNA/RNA helicase activity	G3BP1 PIF1	6.23e-05	4	65	2	GO:0033677
GeneOntologyMolecularFunction	ribosomal protein S6 kinase activity	RPS6KA3 RPS6KA6	2.17e-04	7	65	2	GO:0004711
Domain	Ribosomal_S6_kinase_II	RPS6KA3 RPS6KA6	1.72e-04	6	64	2	IPR016239
Domain	PSI	ATRN SEMA4B ATRNL1	1.77e-04	32	64	3	PF01437
Domain	Plexin_repeat	ATRN SEMA4B ATRNL1	1.77e-04	32	64	3	IPR002165
Domain	PSI	ATRN SEMA4B ATRNL1	4.60e-04	44	64	3	IPR016201
Domain	PSI	ATRN SEMA4B ATRNL1	5.24e-04	46	64	3	SM00423
Domain	ARM-type_fold	DOCK3 MRO UNC45B HSF2BP TEX10 RYR3	1.06e-03	339	64	6	IPR016024
Domain	DH_1	ARHGEF9 OBSCN ARHGEF15	1.32e-03	63	64	3	PS00741
Domain	Homeobox_KN	TGIF2LY TGIF2LX	1.52e-03	17	64	2	PF05920
Domain	Homeobox_KN_domain	TGIF2LY TGIF2LX	1.52e-03	17	64	2	IPR008422
Domain	RhoGEF	ARHGEF9 OBSCN ARHGEF15	1.64e-03	68	64	3	SM00325
Domain	RhoGEF	ARHGEF9 OBSCN ARHGEF15	1.78e-03	70	64	3	PF00621
Domain	DH_2	ARHGEF9 OBSCN ARHGEF15	1.78e-03	70	64	3	PS50010
Domain	DH-domain	ARHGEF9 OBSCN ARHGEF15	1.86e-03	71	64	3	IPR000219
Domain	-	ARHGEF9 OBSCN ARHGEF15	1.86e-03	71	64	3	1.20.900.10
Domain	EGF_LAM_2	ATRN ATRNL1	4.73e-03	30	64	2	PS50027
Domain	EGF_LAM_1	ATRN ATRNL1	4.73e-03	30	64	2	PS01248
Domain	LRR	LRRC55 LRRC37A3 LRRC27 DNAAF1	5.00e-03	201	64	4	PS51450
Domain	EGF_Lam	ATRN ATRNL1	6.39e-03	35	64	2	SM00180
Domain	SH3	DOCK3 SPTA1 ARHGEF9 OBSCN	6.43e-03	216	64	4	SM00326
Domain	SH3	DOCK3 SPTA1 ARHGEF9 OBSCN	6.43e-03	216	64	4	PS50002
Domain	LRR_1	LRRC55 LRRC37A3 LRRC27 DNAAF1	6.75e-03	219	64	4	PF00560
Domain	PTPc	PTPRN PTPN23	6.76e-03	36	64	2	SM00194
Domain	SH3_domain	DOCK3 SPTA1 ARHGEF9 OBSCN	6.86e-03	220	64	4	IPR001452
Domain	-	MRO UNC45B HSF2BP TEX10	7.07e-03	222	64	4	1.25.10.10
Domain	Pkinase_C	RPS6KA3 RPS6KA6	7.13e-03	37	64	2	IPR017892
Domain	SERPIN	SERPINA13P SERPINA5	7.13e-03	37	64	2	SM00093
Domain	Serpin	SERPINA13P SERPINA5	7.51e-03	38	64	2	PF00079
Domain	Laminin_EGF	ATRN ATRNL1	7.51e-03	38	64	2	IPR002049
Domain	GDS_CDC24_CS	OBSCN ARHGEF15	7.89e-03	39	64	2	IPR001331
Domain	Serpin_fam	SERPINA13P SERPINA5	7.89e-03	39	64	2	IPR000215
Domain	TYR_PHOSPHATASE_PTP	PTPRN PTPN23	7.89e-03	39	64	2	PS50055
Domain	PTPase_domain	PTPRN PTPN23	8.70e-03	41	64	2	IPR000242
Domain	Y_phosphatase	PTPRN PTPN23	8.70e-03	41	64	2	PF00102
Domain	Pkinase_C	RPS6KA3 RPS6KA6	9.11e-03	42	64	2	PF00433
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	POLR2B OBSCN HSF2BP SRCIN1 HERC1 TEX10 CNOT1 CHTOP RYR3	4.74e-07	497	67	9	36774506
Pubmed	Hepatitis B Virus HBx Protein Mediates the Degradation of Host Restriction Factors through the Cullin 4 DDB1 E3 Ubiquitin Ligase Complex.	G3BP1 SPTA1 POLR2B OBSCN SRCIN1 TEX10 CNOT1	2.02e-06	304	67	7	32235678
Pubmed	Expression of a novel TGIF subclass homeobox gene, Tex1, in the spermatids of mouse testis during spermatogenesis.	TGIF2LY TGIF2LX	3.66e-06	2	67	2	11960710
Pubmed	Association of TGIFLX/Y mRNA expression with prostate cancer.	TGIF2LY TGIF2LX	3.66e-06	2	67	2	18663611
Pubmed	The human-specific Yp11.2/Xq21.3 homology block encodes a potentially functional testis-specific TGIF-like retroposon.	TGIF2LY TGIF2LX	3.66e-06	2	67	2	12226713
Pubmed	Association of TGIFLX/Y mRNA expression with azoospermia in infertile men.	TGIF2LY TGIF2LX	3.66e-06	2	67	2	18384077
Pubmed	Genetic analysis of attractin homologs.	ATRN ATRNL1	3.66e-06	2	67	2	18064672
Pubmed	Oncostatin M regulates macrophages polarization in osseointegration via yes-associated protein.	OSM YAP1	3.66e-06	2	67	2	37220694
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DHX15 ACSL1 G3BP1 TCERG1 MYH14 POLD2 POLR2B PTPN23 DGKD EIF3B TEX10 CHTOP	9.47e-06	1353	67	12	29467282
Pubmed	Osteal Tissue Macrophages Are Involved in Endplate Osteosclerosis through the OSM-STAT3/YAP1 Signaling Axis in Modic Changes.	OSM YAP1	1.10e-05	3	67	2	32690652
Pubmed	The ARF tumor suppressor regulates bone remodeling and osteosarcoma development in mice.	CDKN2A IL2RG	1.10e-05	3	67	2	21209895
Pubmed	The DNA sequence of the human X chromosome.	ZCCHC18 RPS6KA3 ARHGEF9 RPS6KA6 TGIF2LX CXorf58 SSX8P	1.36e-05	407	67	7	15772651
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	DHX15 CDKN2A G3BP1 MYH14 YAP1 POLD2 RPS6KA3 POLR2B PTPN23 EIF3B HERC1 CNOT1	1.95e-05	1455	67	12	22863883
Pubmed	Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS.	CDKN2A G3BP1 RASSF2 RPS6KA3 POLR2B HAUS5 EIF3B	1.99e-05	432	67	7	23455922
Pubmed	CARMA1 is a novel regulator of T-ALL disease and leukemic cell migration to the CNS.	CARD11 IL2RG	2.19e-05	4	67	2	27698445
Pubmed	Molecular cloning of a mouse scavenger receptor with C-type lectin (SRCL)(1), a novel member of the scavenger receptor family.	TGIF2LY TGIF2LX	2.19e-05	4	67	2	11718900
Pubmed	Loss of p19Arf in a Rag1(-/-) B-cell precursor population initiates acute B-lymphoblastic leukemia.	CDKN2A IL2RG	2.19e-05	4	67	2	21622646
Pubmed	Expression pattern of the Rsk2, Rsk4 and Pdk1 genes during murine embryogenesis.	RPS6KA3 RPS6KA6	2.19e-05	4	67	2	12711546
Pubmed	RSK2 is a modulator of craniofacial development.	RPS6KA3 RPS6KA6	3.64e-05	5	67	2	24416220
Pubmed	Expression pattern of TG-interacting factor 2 during mouse development.	TGIF2LY TGIF2LX	3.64e-05	5	67	2	15749073
Pubmed	Genetic and phenotypic studies of the dark-like mutant mouse.	ATRN ATRNL1	3.64e-05	5	67	2	18821597
Pubmed	The RSK2-RPS6 axis promotes axonal regeneration in the peripheral and central nervous systems.	RPS6KA3 RPS6KA6	3.64e-05	5	67	2	37068088
Pubmed	Cognitive impairment in Coffin-Lowry syndrome correlates with reduced RSK2 activation.	RPS6KA3 RPS6KA6	3.64e-05	5	67	2	11160957
Pubmed	Quantitative interaction proteomics of neurodegenerative disease proteins.	CDKN2A G3BP1 HAUS5 OBSCN EIF3B CHTOP	3.80e-05	323	67	6	25959826
Pubmed	Viral Infection-Induced Differential Expression of LncRNAs Associated with Collagen in Mouse Placentas and Amniotic Sacs.	ATRN RASSF2 SNX21 ARHGEF15	4.29e-05	100	67	4	26073538
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK3 SEMA4B RASSF2 ATRNL1 PTPN23 DGKD ARHGEF15	4.60e-05	493	67	7	15368895
Pubmed	Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity.	RPS6KA3 RPS6KA6	5.46e-05	6	67	2	12832467
Pubmed	eEF2 and Ras-GAP SH3 domain-binding protein (G3BP1) modulate stress granule assembly during HIV-1 infection.	G3BP1 EIF3B	5.46e-05	6	67	2	25229650
Pubmed	gp130 Controls Cardiomyocyte Proliferation and Heart Regeneration.	OSM YAP1	5.46e-05	6	67	2	32600062
Pubmed	CDK8-mediated STAT1-S727 phosphorylation restrains NK cell cytotoxicity and tumor surveillance.	CDKN2A IL2RG	5.46e-05	6	67	2	23933255
Pubmed	Actin remodelling factors control ciliogenesis by regulating YAP/TAZ activity and vesicle trafficking.	YAP1 TESK1	5.46e-05	6	67	2	25849865
Pubmed	A directed protein interaction network for investigating intracellular signal transduction.	DHX15 OSM YAP1 RPS6KA3 HAUS5 RPS6KA6 TCF25 HSF2BP DGKD CARD11	5.56e-05	1124	67	10	21900206
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	DHX15 CDKN2A G3BP1 TCERG1 MYH14 RPS6KA3 PTRH1 TEX10 CNOT1 SERPINA5 CHTOP	5.80e-05	1371	67	11	36244648
Pubmed	GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.	DHX15 TCERG1 POLR2B EIF3B CNOT1	6.94e-05	221	67	5	29991511
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	DHX15 G3BP1 TCERG1 MYH14 POLR2B PTRH1 TCF25 EIF3B TEX10	8.36e-05	949	67	9	36574265
Pubmed	METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.	CDKN2A G3BP1 MYH14 HERC1 RYR3	8.55e-05	231	67	5	36597993
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	ACSL1 INTS6 TCERG1 POLR2B TCF25 TEX10 CNOT1	1.02e-04	560	67	7	35241646
Pubmed	Release of Ubiquitinated and Non-ubiquitinated Nascent Chains from Stalled Mammalian Ribosomal Complexes by ANKZF1 and Ptrh1.	PTRH1 TCF25	1.30e-04	9	67	2	30244831
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	DHX15 G3BP1 MYH14 POLR2B HAUS5 EIF3B TEX10 CNOT1 CHTOP	1.48e-04	1024	67	9	24711643
Pubmed	RNF219/α-Catenin/LGALS3 Axis Promotes Hepatocellular Carcinoma Bone Metastasis and Associated Skeletal Complications.	YAP1 CHTOP	1.63e-04	10	67	2	33643786
Pubmed	NEDDylation promotes stress granule assembly.	G3BP1 EIF3B	1.63e-04	10	67	2	27381497
Pubmed	TRIM21 promotes ubiquitination of SARS-CoV-2 nucleocapsid protein to regulate innate immunity.	G3BP1 TCF25	1.63e-04	10	67	2	37185839
Pubmed	ELOF1 is a transcription-coupled DNA repair factor that directs RNA polymerase II ubiquitylation.	INTS6 POLR2B B4GALT5	2.06e-04	59	67	3	34108663
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	DHX15 G3BP1 TCERG1 MYH14 POLR2B EIF3B	2.09e-04	441	67	6	31239290
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	DHX15 CDKN2A G3BP1 TCERG1 MYH14 EIF3B TEX10 CHTOP	2.20e-04	847	67	8	35850772
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	DHX15 G3BP1 TCERG1 POLR2B PTPN23 EIF3B CNOT1	2.27e-04	638	67	7	33239621
Pubmed	WW domains provide a platform for the assembly of multiprotein networks.	DHX15 G3BP1 TCERG1 POLR2B	2.28e-04	154	67	4	16055720
Pubmed	The transcription elongation factor CA150 interacts with RNA polymerase II and the pre-mRNA splicing factor SF1.	TCERG1 YAP1	2.38e-04	12	67	2	11604498
Pubmed	G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.	G3BP1 EIF3B	2.38e-04	12	67	2	27022092
Pubmed	The p300/YY1/miR-500a-5p/HDAC2 signalling axis regulates cell proliferation in human colorectal cancer.	DHX15 G3BP1 RPS6KA3 TCF25 EIF3B	2.79e-04	298	67	5	30737378
Pubmed	Transcriptional cofactor CA150 regulates RNA polymerase II elongation in a TATA-box-dependent manner.	TCERG1 POLR2B	2.81e-04	13	67	2	10373521
Pubmed	Ubc9 fusion-directed SUMOylation identifies constitutive and inducible SUMOylation.	RPS6KA6 HSF2BP	3.28e-04	14	67	2	17709345
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	DHX15 CDKN2A G3BP1 TCERG1 MYH14 POLR2B EIF3B TESK1 CNOT1 CHTOP	3.82e-04	1425	67	10	30948266
Pubmed	Enhancer Activity Requires CBP/P300 Bromodomain-Dependent Histone H3K27 Acetylation.	DHX15 CDKN2A EIF3B CHTOP	4.12e-04	180	67	4	30110629
Pubmed	Regenerative Reprogramming of the Intestinal Stem Cell State via Hippo Signaling Suppresses Metastatic Colorectal Cancer.	YAP1 IL2RG	4.31e-04	16	67	2	32730753
Pubmed	Proteome-wide analysis of USP14 substrates revealed its role in hepatosteatosis via stabilization of FASN.	DHX15 G3BP1 MYH14 OBSCN CNOT1	4.70e-04	334	67	5	30425250
Pubmed	Definitive hematopoiesis requires Runx1 C-terminal-mediated subnuclear targeting and transactivation.	CDKN2A YAP1	4.88e-04	17	67	2	20035012
Pubmed	Five friends of methylated chromatin target of protein-arginine-methyltransferase[prmt]-1 (chtop), a complex linking arginine methylation to desumoylation.	TEX10 CHTOP	4.88e-04	17	67	2	22872859
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	DHX15 CDKN2A G3BP1 TCERG1 EIF3B TEX10 CHTOP	5.13e-04	731	67	7	29298432
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	ATRN ZNF793 INTS6 LMF1 MYH14 LRRC27 ARHGEF9 OBSCN SRCIN1 CNOT1	5.38e-04	1489	67	10	28611215
Pubmed	CA150, a nuclear protein associated with the RNA polymerase II holoenzyme, is involved in Tat-activated human immunodeficiency virus type 1 transcription.	TCERG1 POLR2B	5.48e-04	18	67	2	9315662
Pubmed	Cdh1-APC Regulates Protein Synthesis and Stress Granules in Neurons through an FMRP-Dependent Mechanism.	G3BP1 TCF25 EIF3B TEX10	5.79e-04	197	67	4	32434143
Pubmed	Genetic polymorphisms in 85 DNA repair genes and bladder cancer risk.	CDKN2A POLD2 POLR2B	5.82e-04	84	67	3	19237606
Pubmed	14-3-3sigma controls mitotic translation to facilitate cytokinesis.	DHX15 G3BP1 CHTOP	6.24e-04	86	67	3	17361185
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	G3BP1 TCERG1 POLR2B TCF25 TEX10 CNOT1 CHTOP	6.41e-04	759	67	7	35915203
Pubmed	C9orf72 protein quality control by UBR5-mediated heterotypic ubiquitin chains.	DHX15 ACSL1 CDKN2A G3BP1 TCERG1 POLD2 POLR2B EIF3B CNOT1	6.64e-04	1257	67	9	37317656
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	TCERG1 YAP1 POLR2B HAUS5 PTPN23 CNOT1	6.65e-04	549	67	6	38280479
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	CDKN2A G3BP1 POLR2B TCF25 CNOT1	6.93e-04	364	67	5	24778252
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	DHX15 TCERG1 YAP1 POLD2 POLR2B EIF3B TEX10 CHTOP	7.24e-04	1014	67	8	32416067
Pubmed	Sequence organization and matrix attachment regions of the human serine protease inhibitor gene cluster at 14q32.1.	SERPINA13P SERPINA5	7.50e-04	21	67	2	15014966
Pubmed	Human Cytomegalovirus UL135 Interacts with Host Adaptor Proteins To Regulate Epidermal Growth Factor Receptor and Reactivation from Latency.	MYH14 IL2RG	8.24e-04	22	67	2	30089695
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	DHX15 CDKN2A ATRN G3BP1 POLD2 POLR2B PTRH1 PTPN23 CNOT1	8.29e-04	1297	67	9	33545068
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	DHX15 CDKN2A G3BP1 TCERG1 POLR2B CNOT1 CHTOP	9.17e-04	807	67	7	22681889
Pubmed	Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs.	G3BP1 YAP1	9.82e-04	24	67	2	37100772
Pubmed	Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.	SEMA4B LRRC27 SRCIN1	1.02e-03	102	67	3	11214970
Pubmed	FBW7 suppresses ovarian cancer development by targeting the N6-methyladenosine binding protein YTHDF2.	G3BP1 MYH14 POLR2B TCF25 TEX10 CHTOP	1.06e-03	601	67	6	33658012
Pubmed	The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer.	INTS6 POLR2B	1.07e-03	25	67	2	34004147
Pubmed	Human Sos1: a guanine nucleotide exchange factor for Ras that binds to GRB2.	SPTA1 IL2RG	1.07e-03	25	67	2	8493579
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ATRNL1 POLD2 RPS6KA3 POLR2B OBSCN PTPN23 HERC1 CNOT1	1.11e-03	1084	67	8	11544199
Pubmed	Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	ATRN LRRC37A3 ATRNL1	1.11e-03	105	67	3	9628581
Pubmed	Deletion of yes-associated protein (YAP) specifically in cardiac and vascular smooth muscle cells reveals a crucial role for YAP in mouse cardiovascular development.	CDKN2A YAP1	1.15e-03	26	67	2	24478334
Pubmed	ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes.	DHX15 POLR2B EIF3B	1.18e-03	107	67	3	20508642
Pubmed	Nuclear lamina genetic variants, including a truncated LAP2, in twins and siblings with nonalcoholic fatty liver disease.	DHX15 MYH14 RPS6KA3 EIF3B	1.28e-03	244	67	4	28902428
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	DHX15 G3BP1 MYH14 YAP1 EIF3B CHTOP	1.31e-03	626	67	6	33644029
Pubmed	Interactomes of SARS-CoV-2 and human coronaviruses reveal host factors potentially affecting pathogenesis.	SEMA4B G3BP1	1.34e-03	28	67	2	34232536
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CDKN2A INTS6 OSM POLR2B HAUS5 TCF25 ABCA7 CHTOP	1.34e-03	1116	67	8	31753913
Pubmed	SLFN11 promotes CDT1 degradation by CUL4 in response to replicative DNA damage, while its absence leads to synthetic lethality with ATR/CHK1 inhibitors.	DHX15 TCERG1 MYH14 EIF3B	1.40e-03	250	67	4	33536335
Pubmed	The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.	MYH14 POLR2B TEX10 CNOT1	1.46e-03	253	67	4	29911972
Pubmed	Oncogenic functions of protein kinase D2 and D3 in regulating multiple cancer-related pathways in breast cancer.	G3BP1 MYH14 LRRC27	1.48e-03	116	67	3	30652415
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	DHX15 G3BP1 MYH14 POLR2B TEX10 CHTOP	1.61e-03	652	67	6	31180492
Pubmed	Human transcription factor protein interaction networks.	CDKN2A G3BP1 TCERG1 MYH14 YAP1 EIF3B HERC1 TEX10 CNOT1	1.63e-03	1429	67	9	35140242
Pubmed	Interaction proteome of human Hippo signaling: modular control of the co-activator YAP1.	DHX15 G3BP1 RASSF2 YAP1	1.86e-03	270	67	4	24366813
Pubmed	Cold-induced protein RBM3 orchestrates neurogenesis via modulating Yap mRNA stability in cold stress.	CDKN2A YAP1	1.86e-03	33	67	2	30037926
GeneFamily	Mitogen-activated protein kinase-activated protein kinases	RPS6KA3 RPS6KA6	3.14e-04	11	44	2	1156
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ARHGEF9 OBSCN ARHGEF15	5.53e-04	66	44	3	722
GeneFamily	TALE class homeoboxes and pseudogenes	TGIF2LY TGIF2LX	1.81e-03	26	44	2	526
GeneFamily	Serpin peptidase inhibitors	SERPINA13P SERPINA5	3.65e-03	37	44	2	739
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	ATRN ATRNL1	4.47e-03	41	44	2	1298
Coexpression	GSE9006_HEALTHY_VS_TYPE_2_DIABETES_PBMC_AT_DX_DN	DHX15 ACSL1 POLR2B CDH10 CHTOP B4GALT5	1.07e-05	198	66	6	M5782
Disease	T-cell acute lymphoblastic leukemia (is_marker_for)	CDKN2A CARD11	1.34e-05	3	63	2	DOID:5603 (is_marker_for)
Disease	Sezary Syndrome	CDKN2A CARD11 IL2RG	2.62e-05	27	63	3	C0036920
Disease	Coffin-Lowry syndrome (implicated_via_orthology)	RPS6KA3 RPS6KA6	2.68e-05	4	63	2	DOID:3783 (implicated_via_orthology)
Disease	alpha-1-antichymotrypsin complex measurement	SERPINA13P SERPINA5	9.36e-05	7	63	2	EFO_0008018
Disease	Liver Cirrhosis, Experimental	ACSL1 ATRN OSM FRY MRO PTRH1 IL2RG B4GALT5	2.34e-04	774	63	8	C0023893
Disease	Granulomatous Slack Skin	CDKN2A CARD11	1.01e-03	22	63	2	C0376407
Disease	Lymphoma, T-Cell, Cutaneous	CDKN2A CARD11	1.10e-03	23	63	2	C0079773
Disease	Lymphatic Metastasis	CDKN2A RASSF2	1.41e-03	26	63	2	C0024232

Protein segments in the cluster

Peptide	Gene	Start	Entry
LVLLRPRRLMNANGR	PTRH1	86	Q86Y79
FLLRQEGRPMVNLIR	ARSK	151	Q6UWY0
MQLPTRQEIRVRNLF	EIF3B	496	P55884
SNRLRNEMKFLLQRP	CXorf58	231	Q96LI9
VPRLLNRMFDRIFGQ	ACSL1	366	P33121
VLMLLRSQRLGQQPL	CDKN2A	46	Q8N726
PFQRITRLRMLLQNI	ARHGEF15	556	O94989
RQQLSRIMDRFNLPR	DHX15	661	O43143
FRHLLPMLQRQRLQF	B4GALT5	181	O43286
LLQMQDEGRRQPRPG	ABCA7	351	Q8IZY2
LCLGRPLQNRDQMRA	ARHGEF9	91	O43307
GLRRPIRLQMQDDNE	RASSF2	61	P50749
RRRCMSPLLRGRQQN	INTS6	656	Q9UL03
NGIPELPQLVRRMRQ	PTPN23	1416	Q9H3S7
QRLQGVLRQLMSQGL	PTPRN	81	Q16849
RQRLNRVLMGPRSIQ	LRRC37A3	1161	O60309
RRVHPQAFQGLMQLR	LRRC55	151	Q6ZSA7
QSLLRMLFKRNPANR	RPS6KA3	296	P51812
LIEGQPNRIMRLRFN	ATRN	161	O75882
GRQAGPLRNLLFRLM	HERC1	816	Q15751
QQAMQRLLGERLTPR	CABP5	131	Q9NP86
TRLIQMRPFLENRAQ	POLD2	56	P49005
GRRLRLPRDQIQRMN	MYH14	86	Q7Z406
MDQRQRRILGQPLSI	MRO	1	Q9BYG7
QSLLRMLFKRNPANR	RPS6KA6	301	Q9UK32
HTLRDPMQRLQNQLR	HAUS5	141	O94927
GAMLELVVRNLRPQD	OBSCN	3236	Q5VST9
IRRENPMIFNRGLAI	DOCK3	391	Q8IZD9
GIIRTALPNMNRENR	CDH10	216	Q9Y6N8
SNRPIMFRGEVRLNV	G3BP1	396	Q13283
RLNSQRLVFNRPFLM	SERPINA5	376	P05154
QLLRERQQMASRPFA	ATRNL1	1266	Q5VV63
QLQDPREPRRQATQM	IL2RG	131	P31785
DLRVLNLMGNPVIRQ	DNAAF1	246	Q8NEP3
QIFRPREQLMLRANS	DGKD	601	Q16760
NPERMNIGLRAFLVI	FRY	491	Q5TBA9
PQRRMNLKGIQLQRA	CARD11	496	Q9BXL7
GRNERRELMLRLQAP	PIF1	46	Q9H611
MQIRDFLPRILNGEV	HSF2BP	36	O75031
FINARRRILPDMLQQ	TGIF2LX	101	Q8IUE1
RRILPDMLQQRRNDP	TGIF2LX	106	Q8IUE1
FINARRRILPDMLQQ	TGIF2LY	101	Q8IUE0
RRILPDMLQQRRNDP	TGIF2LY	106	Q8IUE0
QQLRDNMGSRRDPLV	TBC1D25	511	Q3MII6
LQMREQRRFHGQAPL	LRRC27	446	Q9C0I9
GQVRSRMLLLQPQAR	SEMA4B	431	Q9NPR2
PIQILNRQPMEGRSR	POLR2B	1066	P30876
LQMARPNILGLRNNI	OSM	136	P13725
RNRRLAQQMENRPSV	CHTOP	51	Q9Y3Y2
IQLRNLILSAFPRNM	CNOT1	2126	A5YKK6
LEPRNQNFQEMLRRL	UNC45B	106	Q8IWX7
NIQRKRRQDMLLRPG	ZNF793	86	Q6ZN11
PQPLVNMRRFILERN	ZNF826P	51	Q6ZT77
LALRGQQDRMREQPN	SRCIN1	96	Q9C0H9
PGELRMAQQQALRFR	TCERG1	16	O14776
MLQQLLRRLVFDVPQ	RYR3	2481	Q15413
RIQVERPQMTFGRLQ	SSX8P	91	Q7RTT4
ERLHRNLQRQFRGPM	SNX21	176	Q969T3
PRLDPRFAMNQRISQ	YAP1	261	P46937
RLMLQSLRVNRVGPE	TEX10	841	Q9NXF1
LRGQGPRLLLTMDQR	SERPINA13P	126	Q6UXR4
VQLMNRLRHPNILRF	TESK1	101	Q15569
MLPQRRREEPGNITQ	SPTA1	1041	P02549
RGPAREVMRLLQAAN	ZCCHC18	91	P0CG32
FPNVLNVARLLRMAL	ZNF818P	116	Q6ZRF7
RRDNPRFNLMLGERN	TTL	31	Q8NG68
RFNLMLGERNRLPFG	TTL	36	Q8NG68
LNRNQGLNRLMLAVR	TCF25	636	Q9BQ70
QRMGLRSLRGIVPNL	KIAA1958	671	Q8N8K9
DRVLQMQRDIRGARP	LMF1	341	Q96S06