Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	scavenger receptor activity	LGALS3BP AGER CD36 SCARB2 PRG4	9.74e-07	27	136	5	GO:0005044
GeneOntologyMolecularFunction	cargo receptor activity	LGALS3BP AGER CD36 SCARB2 CD44 PRG4	2.51e-05	85	136	6	GO:0038024
GeneOntologyMolecularFunction	IMP dehydrogenase activity	IMPDH1 IMPDH2	4.60e-05	2	136	2	GO:0003938
GeneOntologyMolecularFunction	protein serine/threonine kinase activator activity	TOPBP1 NBN RICTOR DELE1 STRADA	1.93e-04	78	136	5	GO:0043539
GeneOntologyMolecularFunction	phosphotyrosine residue binding	PTPN5 SH2D1B HCK NCK2	4.01e-04	51	136	4	GO:0001784
GeneOntologyMolecularFunction	protein kinase activator activity	MAP3K20 TOPBP1 NBN RICTOR DELE1 STRADA	5.53e-04	149	136	6	GO:0030295
GeneOntologyBiologicalProcess	positive regulation of cellular component organization	FN1 TCP1 ADAM9 NBN RICTOR TUBB2B DELE1 ACVRL1 NPHP4 PTPN5 MAGI2 SETDB2 IGHG1 AGER CD36 SCARB2 WDR35 AHR MIEF1 KIF3C MAD2L2 HCK PHIP GNL3 PLXNA2 MPP7 NCK2	2.37e-07	1366	136	27	GO:0051130
GeneOntologyBiologicalProcess	positive regulation of protein modification process	ADAM9 NBN RICTOR LRRK1 ITGA5 PTPN5 MAGI2 SLC8A2 SH2D1B CSNK1D STRADA AGER CD36 CHFR CD44 MAD2L2 PHIP GNL3 NCK2	1.28e-05	937	136	19	GO:0031401
GeneOntologyBiologicalProcess	positive regulation of phosphorus metabolic process	ADAM9 NBN RICTOR LRRK1 ITGA5 PTPN5 MAGI2 SLC8A2 SH2D1B CSNK1D STRADA AGER CD36 CD44 KCTD20 MAD2L2 PHIP NCK2	1.94e-05	879	136	18	GO:0010562
GeneOntologyBiologicalProcess	positive regulation of phosphate metabolic process	ADAM9 NBN RICTOR LRRK1 ITGA5 PTPN5 MAGI2 SLC8A2 SH2D1B CSNK1D STRADA AGER CD36 CD44 KCTD20 MAD2L2 PHIP NCK2	1.94e-05	879	136	18	GO:0045937
GeneOntologyBiologicalProcess	signal transduction in response to DNA damage	TTI2 DTL MAP3K20 TOPBP1 NBN PLA2R1 CD44 MAD2L2	5.54e-05	200	136	8	GO:0042770
GeneOntologyBiologicalProcess	positive regulation of phosphorylation	ADAM9 NBN RICTOR LRRK1 ITGA5 PTPN5 SLC8A2 SH2D1B CSNK1D STRADA AGER CD36 CD44 KCTD20 MAD2L2 PHIP	5.70e-05	780	136	16	GO:0042327
GeneOntologyBiologicalProcess	positive regulation of protein phosphorylation	ADAM9 NBN RICTOR LRRK1 ITGA5 PTPN5 SLC8A2 SH2D1B CSNK1D STRADA AGER CD36 CD44 MAD2L2 PHIP	8.83e-05	724	136	15	GO:0001934
GeneOntologyBiologicalProcess	monocyte activation	FN1 ADAM9 FOXP1	9.68e-05	14	136	3	GO:0042117
GeneOntologyBiologicalProcess	regulation of protein modification process	FN1 ADAM9 HDAC8 NBN RICTOR LRRK1 ITGA5 DICER1 PTPN5 NPFFR2 MAGI2 SLC8A2 SH2D1B CSNK1D STRADA AGER CD36 CHFR CD44 MAD2L2 PHIP GNL3 NCK2	1.07e-04	1488	136	23	GO:0031399
GeneOntologyBiologicalProcess	positive regulation of programmed cell death	MAP3K20 B4GALT1 PLA2R1 EFHC1 NFATC4 AGER CD44 WDR35 AHR FOXP1 ITM2C MMP2 FBXO32 SLC27A4 NCK2	1.11e-04	739	136	15	GO:0043068
GeneOntologyBiologicalProcess	regulation of phosphorylation	FN1 ADAM9 NBN RICTOR LRRK1 ITGA5 DICER1 PTPN5 NPFFR2 SLC8A2 SH2D1B CSNK1D STRADA AGER CD36 CD44 KCTD20 MAD2L2 PHIP NCK2	1.57e-04	1226	136	20	GO:0042325
GeneOntologyBiologicalProcess	regulation of protein phosphorylation	FN1 ADAM9 NBN RICTOR LRRK1 ITGA5 DICER1 PTPN5 NPFFR2 SLC8A2 SH2D1B CSNK1D STRADA AGER CD36 CD44 MAD2L2 PHIP NCK2	1.64e-04	1133	136	19	GO:0001932
Domain	RICIN	CRYBG2 GALNT13 PLA2R1 CRYBG3	4.15e-05	28	131	4	SM00458
Domain	RICIN_B_LECTIN	CRYBG2 GALNT13 PLA2R1 CRYBG3	4.15e-05	28	131	4	PS50231
Domain	IMP_DH	IMPDH1 IMPDH2	4.88e-05	2	131	2	IPR005990
Domain	Ricin_B_lectin	CRYBG2 GALNT13 PLA2R1 CRYBG3	5.50e-05	30	131	4	IPR000772
Domain	-	FN1 PLA2R1 MMP2	9.16e-05	13	131	3	2.10.10.10
Domain	FN_type2_col-bd	FN1 PLA2R1 MMP2	1.16e-04	14	131	3	IPR000562
Domain	FN2_2	FN1 PLA2R1 MMP2	1.16e-04	14	131	3	PS51092
Domain	FN2_1	FN1 PLA2R1 MMP2	1.16e-04	14	131	3	PS00023
Domain	fn2	FN1 PLA2R1 MMP2	1.16e-04	14	131	3	PF00040
Domain	FN2	FN1 PLA2R1 MMP2	1.16e-04	14	131	3	SM00059
Domain	CD36_fam	CD36 SCARB2	1.46e-04	3	131	2	IPR002159
Domain	CD36	CD36 SCARB2	1.46e-04	3	131	2	PF01130
Domain	IMPDH	IMPDH1 IMPDH2	2.90e-04	4	131	2	PF00478
Domain	IMP_DH_GMPRt	IMPDH1 IMPDH2	2.90e-04	4	131	2	IPR001093
Domain	IMP_DH_GMP_RED	IMPDH1 IMPDH2	2.90e-04	4	131	2	PS00487
Domain	IMP_DH/GMP_Rdtase_CS	IMPDH1 IMPDH2	2.90e-04	4	131	2	IPR015875
Domain	Ricin_B_lectin	CRYBG2 GALNT13 CRYBG3	6.93e-04	25	131	3	PF00652
Domain	fn3	COL12A1 FN1 FSD2 ITGB4 USH2A SDK1	9.94e-04	162	131	6	PF00041
Domain	-	BAZ2B SETDB2	1.33e-03	8	131	2	3.30.890.10
Domain	Calx_beta	ITGB4 SLC8A2	1.33e-03	8	131	2	SM00237
Domain	Kringle-like	FN1 PLA2R1 MMP2	1.44e-03	32	131	3	IPR013806
Domain	Calx_beta	ITGB4 SLC8A2	1.70e-03	9	131	2	IPR003644
Domain	Pept_M24	XPNPEP2 PA2G4	1.70e-03	9	131	2	IPR000994
Domain	BRICHOS	ITM2C ITM2A	1.70e-03	9	131	2	SM01039
Domain	BRICHOS_dom	ITM2C ITM2A	1.70e-03	9	131	2	IPR007084
Domain	BRICHOS	ITM2C ITM2A	1.70e-03	9	131	2	PF04089
Domain	Peptidase_M24	XPNPEP2 PA2G4	1.70e-03	9	131	2	PF00557
Domain	-	XPNPEP2 PA2G4	1.70e-03	9	131	2	3.90.230.10
Domain	Calx-beta	ITGB4 SLC8A2	1.70e-03	9	131	2	PF03160
Domain	BRICHOS	ITM2C ITM2A	1.70e-03	9	131	2	PS50869
Domain	FN3	COL12A1 FN1 FSD2 ITGB4 USH2A SDK1	1.96e-03	185	131	6	SM00060
Domain	BROMODOMAIN_1	BAZ2B ATAD2 PHIP	2.20e-03	37	131	3	PS00633
Domain	Bromodomain	BAZ2B ATAD2 PHIP	2.38e-03	38	131	3	PF00439
Domain	MBD	BAZ2B SETDB2	2.58e-03	11	131	2	SM00391
Domain	MBD	BAZ2B SETDB2	2.58e-03	11	131	2	PS50982
Domain	Methyl_CpG_DNA-bd	BAZ2B SETDB2	2.58e-03	11	131	2	IPR001739
Domain	MBD	BAZ2B SETDB2	2.58e-03	11	131	2	PF01429
Domain	DNA-bd_dom	BAZ2B SETDB2	2.58e-03	11	131	2	IPR016177
Domain	FN3	COL12A1 FN1 FSD2 ITGB4 USH2A SDK1	2.82e-03	199	131	6	PS50853
Domain	BROMODOMAIN_2	BAZ2B ATAD2 PHIP	2.96e-03	41	131	3	PS50014
Domain	Bromodomain	BAZ2B ATAD2 PHIP	3.17e-03	42	131	3	IPR001487
Domain	BROMO	BAZ2B ATAD2 PHIP	3.17e-03	42	131	3	SM00297
Domain	-	BAZ2B ATAD2 PHIP	3.17e-03	42	131	3	1.20.920.10
Domain	FN3_dom	COL12A1 FN1 FSD2 ITGB4 USH2A SDK1	3.59e-03	209	131	6	IPR003961
Domain	Ig-like_fold	COL12A1 FN1 FSD2 ITGB4 F13A1 IGSF10 NFATC4 IGHG1 AGER USH2A SDK1 PLXNA2	4.07e-03	706	131	12	IPR013783
Domain	Beta/gamma_crystallin	CRYBG2 CRYBG3	4.83e-03	15	131	2	IPR001064
Domain	CRYSTALLIN_BETA_GAMMA	CRYBG2 CRYBG3	4.83e-03	15	131	2	PS50915
Domain	Crystall	CRYBG2 CRYBG3	4.83e-03	15	131	2	PF00030
Domain	XTALbg	CRYBG2 CRYBG3	4.83e-03	15	131	2	SM00247
Domain	CBS	IMPDH1 IMPDH2	5.49e-03	16	131	2	SM00116
Domain	Guanylate_kinase_CS	MAGI2 MPP7	5.49e-03	16	131	2	IPR020590
Domain	SH2	SH2D1B SUPT6H HCK NCK2	5.59e-03	101	131	4	PF00017
Domain	Ig_E-set	CPAMD8 F13A1 NFATC4 PLXNA2	6.19e-03	104	131	4	IPR014756
Domain	Hemopexin_CS	MMP2 PRG4	6.20e-03	17	131	2	IPR018486
Domain	G_crystallin-rel	CRYBG2 CRYBG3	6.94e-03	18	131	2	IPR011024
Pubmed	Regulation of endodermal differentiation of human embryonic stem cells through integrin-ECM interactions.	COL12A1 FN1 ITGA5 ITGB4 MMP2	1.57e-07	32	136	5	23154389
Pubmed	Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.	EMC7 COL12A1 IMPDH2 COPG1 TCP1 ADAM9 CNTNAP1 USP24 KDM3B ITGA5 PRPF8 LGALS3BP POGLUT1 ABHD17B IGHG1 CSNK1D SCARB2 ATP11A NENF GNL3	1.70e-07	1297	136	20	33545068
Pubmed	ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.	EMC7 COL12A1 ADAM9 CNTNAP1 CACHD1 ITGA5 ITGB4 LGALS3BP B4GALT1 IGSF10 PLA2R1 POGLUT1 SCARB2 CD44 ITM2C MMP2 NENF KIF2C	1.12e-06	1201	136	18	35696571
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FN1 IMPDH2 MYO1D COPG1 POLR2A USP24 PRPF8 ATAD2 DICER1 SUPT6H SCAF11 PHIP GNL3	1.88e-06	653	136	13	22586326
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	FN1 IMPDH2 COPG1 TCP1 POLR2A MAP3K20 DOCK10 RICTOR TUBB2B PRPF8 ATAD2 FBXL18 PA2G4 IGHG1 PHIP GNL3 SLC27A4 KIF2C	5.89e-06	1353	136	18	29467282
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	SIN3B FN1 COPG1 TCP1 BAZ2B POLR2A TTI2 PRPF8 IGSF10 AHR MMP2 PRG4 RGL4	6.85e-06	736	136	13	29676528
Pubmed	CTPS and IMPDH form cytoophidia in developmental thymocytes.	IMPDH1 IMPDH2 CD44	6.88e-06	10	136	3	34022203
Pubmed	Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice.	FN1 ITGA5 MMP2	9.43e-06	11	136	3	36465133
Pubmed	Immunolocalization of extracellular matrix components and integrins during mouse liver development.	FN1 ITGA5 ITGB4	9.43e-06	11	136	3	15368439
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	RAPGEF6 IMPDH2 TCP1 ADAM9 DOCK10 KDM3B RICTOR ZNFX1 DICER1 CRYBG3 EPB41L1 SLC27A4	1.01e-05	650	136	12	38777146
Pubmed	Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.	SIN3B BAZ2B ATAD2 DNAH7 PHIP	1.18e-05	75	136	5	25593309
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	EMC7 FN1 COPG1 CNTNAP1 PRPF8 HPDL F13A1 LGALS3BP MAGI2 PLA2R1 POGLUT1 CD44 ITM2C KIF3C MMP2 PRG4 EPB41L1 SLC27A4	1.51e-05	1451	136	18	30550785
Pubmed	Co-expression of CD44v6 and MMP2 predicts lung metastasis and unfavorable prognosis in osteosarcoma.	CD44 MMP2	1.52e-05	2	136	2	39011948
Pubmed	Expression of IMPDH mRNA after mycophenolate administration in male volunteers.	IMPDH1 IMPDH2	1.52e-05	2	136	2	25105143
Pubmed	Genome Maintenance by DNA Helicase B.	TOPBP1 HELB	1.52e-05	2	136	2	32455610
Pubmed	Pharmacogenetics of the mycophenolic acid targets inosine monophosphate dehydrogenases IMPDH1 and IMPDH2: gene sequence variation and functional genomics.	IMPDH1 IMPDH2	1.52e-05	2	136	2	20718729
Pubmed	CK1δ and CK1ε are components of human 40S subunit precursors required for cytoplasmic 40S maturation.	CSNK1D CSNK1E	1.52e-05	2	136	2	24424021
Pubmed	Intrinsic growth deficiencies of mesenchymal stromal cells in myelodysplastic syndromes.	ITGA5 CD44	1.52e-05	2	136	2	21933023
Pubmed	Two distinct cDNAs for human IMP dehydrogenase.	IMPDH1 IMPDH2	1.52e-05	2	136	2	1969416
Pubmed	Regulation of casein kinase I epsilon and casein kinase I delta by an in vivo futile phosphorylation cycle.	CSNK1D CSNK1E	1.52e-05	2	136	2	9632646
Pubmed	Lubricin/Proteoglycan 4 Binding to CD44 Receptor: A Mechanism of the Suppression of Proinflammatory Cytokine-Induced Synoviocyte Proliferation by Lubricin.	CD44 PRG4	1.52e-05	2	136	2	25708025
Pubmed	Dicer ablation promotes a mesenchymal and invasive phenotype in bladder cancer cells.	DICER1 MMP2	1.52e-05	2	136	2	26166215
Pubmed	Hyperhomocysteinemia activates the aryl hydrocarbon receptor/CD36 pathway to promote hepatic steatosis in mice.	CD36 AHR	1.52e-05	2	136	2	26928949
Pubmed	Serotonin (5-HT) inhibits Factor XIII-A-mediated plasma fibronectin matrix assembly and crosslinking in osteoblast cultures via direct competition with transamidation.	FN1 F13A1	1.52e-05	2	136	2	25460579
Pubmed	Targeted disruption of the inosine 5'-monophosphate dehydrogenase type I gene in mice.	IMPDH1 IMPDH2	1.52e-05	2	136	2	12944494
Pubmed	Defining the topology of integrin alpha5beta1-fibronectin interactions using inhibitory anti-alpha5 and anti-beta1 monoclonal antibodies. Evidence that the synergy sequence of fibronectin is recognized by the amino-terminal repeats of the alpha5 subunit.	FN1 ITGA5	1.52e-05	2	136	2	9211865
Pubmed	Overlapping and independent functions of fibronectin receptor integrins in early mesodermal development.	FN1 ITGA5	1.52e-05	2	136	2	10545236
Pubmed	Aryl hydrocarbon receptor regulates histone deacetylase 8 expression to repress tumor suppressive activity in hepatocellular carcinoma.	HDAC8 AHR	1.52e-05	2	136	2	27283490
Pubmed	Megakaryocyte-matrix interaction within bone marrow: new roles for fibronectin and factor XIII-A.	FN1 F13A1	1.52e-05	2	136	2	21131589
Pubmed	Cloning and sequence analysis of the human and Chinese hamster inosine-5'-monophosphate dehydrogenase cDNAs.	IMPDH1 IMPDH2	1.52e-05	2	136	2	2902093
Pubmed	Characterization of human type I and type II IMP dehydrogenases.	IMPDH1 IMPDH2	1.52e-05	2	136	2	7903306
Pubmed	Fibronectin assembly during early embryo development: A versatile communication system between cells and tissues.	FN1 ITGA5	1.52e-05	2	136	2	26845241
Pubmed	Recombinant human inosine monophosphate dehydrogenase type I and type II proteins. Purification and characterization of inhibitor binding.	IMPDH1 IMPDH2	1.52e-05	2	136	2	7763314
Pubmed	CD36 Deficiency Suppresses Epileptic Seizures.	CD36 SCARB2	1.52e-05	2	136	2	29111364
Pubmed	A novel role for the dioxin receptor in fatty acid metabolism and hepatic steatosis.	CD36 AHR	1.52e-05	2	136	2	20303349
Pubmed	Immunohistochemical levels of matrix metalloproteinase-2 and CD44 variant 6 protein in the diagnosis and lateral cervical lymph node metastasis of papillary thyroid carcinoma.	CD44 MMP2	1.52e-05	2	136	2	23685894
Pubmed	Casein kinase I delta/epsilon phosphorylates topoisomerase IIalpha at serine-1106 and modulates DNA cleavage activity.	CSNK1D CSNK1E	1.52e-05	2	136	2	19043076
Pubmed	Inosine 5'-monophosphate dehydrogenase binds nucleic acids in vitro and in vivo.	IMPDH1 IMPDH2	1.52e-05	2	136	2	14766016
Pubmed	Trop2 enhances invasion of thyroid cancer by inducing MMP2 through ERK and JNK pathways.	MMP2 TACSTD2	1.52e-05	2	136	2	28709407
Pubmed	Dicer knockdown induces fibronectin-1 expression in HEK293T cells via induction of Egr1.	FN1 DICER1	1.52e-05	2	136	2	19914350
Pubmed	TopBP1 associates with NBS1 and is involved in homologous recombination repair.	TOPBP1 NBN	1.52e-05	2	136	2	17765870
Pubmed	Characterization of the human inosine-5'-monophosphate dehydrogenase type II gene.	IMPDH1 IMPDH2	1.52e-05	2	136	2	7896827
Pubmed	PRPF8 increases the aggressiveness of hepatocellular carcinoma by regulating FAK/AKT pathway via fibronectin 1 splicing.	FN1 PRPF8	1.52e-05	2	136	2	36609600
Pubmed	Cell adhesion. Fibronectin and integrin knockouts come unstuck.	FN1 ITGA5	1.52e-05	2	136	2	7522915
Pubmed	Expression of Novel CD44st and MMP2 in NSCLC Tissues and Their Clinical Significance.	CD44 MMP2	1.52e-05	2	136	2	28365695
Pubmed	Polymorphisms in type I and II inosine monophosphate dehydrogenase genes and association with clinical outcome in patients on mycophenolate mofetil.	IMPDH1 IMPDH2	1.52e-05	2	136	2	20679962
Pubmed	Expression of inosine monophosphate dehydrogenase type I and type II after mycophenolate mofetil treatment: a 2-year follow-up in kidney transplantation.	IMPDH1 IMPDH2	1.52e-05	2	136	2	17713475
Pubmed	CD36 is differentially expressed by CD8+ splenic dendritic cells but is not required for cross-presentation in vivo.	CD36 SCARB2	1.52e-05	2	136	2	12055215
Pubmed	Human fibronectin and MMP-2 collagen binding domains compete for collagen binding sites and modify cellular activation of MMP-2.	FN1 MMP2	1.52e-05	2	136	2	12225805
Pubmed	Effects of altered expression and activity levels of CK1δ and ɛ on tumor growth and survival of colorectal cancer patients.	CSNK1D CSNK1E	1.52e-05	2	136	2	25404202
Pubmed	Mutants of purine metabolism in cultured mouse and hamster cells.	IMPDH1 IMPDH2	1.52e-05	2	136	2	988789
Pubmed	Expression of CD44 and MMP-2: possible association with histopathological features of pleuro-pulmonary solitary fibrous tumors.	CD44 MMP2	1.52e-05	2	136	2	21630198
Pubmed	Matrix metalloproteinase-2 promotes αvβ3 integrin-mediated adhesion and migration of human melanoma cells by cleaving fibronectin.	FN1 MMP2	1.52e-05	2	136	2	22848537
Pubmed	An evaluation of polymorphisms in casein kinase 1 delta and epsilon genes in major psychiatric disorders.	CSNK1D CSNK1E	1.52e-05	2	136	2	22981886
Pubmed	Integrin alpha5 is involved in fibronectin-induced human extravillous trophoblast invasion.	FN1 ITGA5	1.52e-05	2	136	2	17027088
Pubmed	Extensive vascular remodeling in the spinal cord of pre-symptomatic experimental autoimmune encephalomyelitis mice; increased vessel expression of fibronectin and the α5β1 integrin.	FN1 ITGA5	1.52e-05	2	136	2	24056042
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	IMPDH2 CNTNAP1 RICTOR ZNFX1 PRPF8 ITGB4 DICER1	1.56e-05	202	136	7	33005030
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	ADAM9 RICTOR ATAD2 KLHL38 ADRA1B CD44 ATP11A TACSTD2 PLXNA2 EPB41L1 MPP7	1.58e-05	569	136	11	30639242
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SIN3B IMPDH1 IMPDH2 POLR2A MAP3K20 TOPBP1 NBN RICTOR ATAD2 DICER1 PA2G4 SUPT6H SCAF11 TACSTD2 GNL3 EPB41L1 MPP7 KIF2C	2.29e-05	1497	136	18	31527615
Pubmed	Integrins in the mouse myotome: developmental changes and differences between the epaxial and hypaxial lineage.	FN1 ITGA5 ITGB4	2.57e-05	15	136	3	15366018
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	ADAM9 POLR2A USP24 KDM3B GALNT13 CSNK1D CSNK1E MTM1 MMP2 MAPK10 HCK GNL3	3.17e-05	730	136	12	34857952
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	EMC7 POLR2A DTL KDM3B NBN DICER1 NFATC4 CSNK1E MIEF1 GNL3 SLC27A4 NCK2	3.30e-05	733	136	12	34672954
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	RAPGEF6 DTL MAP3K20 KDM3B RICTOR LYST DNAH7 CSNK1D CSNK1E MIEF1 CRYBG3 EPB41L1 KIF2C	3.53e-05	861	136	13	36931259
Pubmed	Mouse Models of Inherited Retinal Degeneration with Photoreceptor Cell Loss.	IMPDH1 ADAM9 NPHP4 DICER1 CD36 AHR USH2A	3.88e-05	233	136	7	32290105
Pubmed	Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.	EMC7 FN1 IMPDH2 ITGB4 LIPE ITM2C MMP2 MAPK10	4.17e-05	322	136	8	26514267
Pubmed	Adhesion to fibronectin via α5β1 integrin supports expansion of the megakaryocyte lineage in primary myelofibrosis.	FN1 ITGA5	4.54e-05	3	136	2	32294178
Pubmed	Increased expression of fibronectin and the alpha 5 beta 1 integrin in angiogenic cerebral blood vessels of mice subject to hypobaric hypoxia.	FN1 ITGA5	4.54e-05	3	136	2	18343155
Pubmed	Structural insights into integrin α5β1 opening by fibronectin ligand.	FN1 ITGA5	4.54e-05	3	136	2	33962943
Pubmed	Centrosomal anchoring of the protein kinase CK1delta mediated by attachment to the large, coiled-coil scaffolding protein CG-NAP/AKAP450.	CSNK1D CSNK1E	4.54e-05	3	136	2	12270714
Pubmed	Fatty acid transporters in skin development, function and disease.	CD36 SLC27A4	4.54e-05	3	136	2	24120574
Pubmed	Matrix metalloproteinase-2 and -9 differentially regulate smooth muscle cell migration and cell-mediated collagen organization.	CD44 MMP2	4.54e-05	3	136	2	14551157
Pubmed	[CD44 variant increases the invasive ability of human breast cancer cell line MCF-7 cells].	CD44 MMP2	4.54e-05	3	136	2	20211062
Pubmed	Human immunodeficiency virus type 1 tat protein modulates fibronectin expression in thymic epithelial cells and impairs in vitro thymocyte development.	FN1 ITGA5	4.54e-05	3	136	2	8599839
Pubmed	The interaction of amyloid β and the receptor for advanced glycation endproducts induces matrix metalloproteinase-2 expression in brain endothelial cells.	AGER MMP2	4.54e-05	3	136	2	21837459
Pubmed	T cell activation triggers reversible inosine-5'-monophosphate dehydrogenase assembly.	IMPDH1 IMPDH2	4.54e-05	3	136	2	30154209
Pubmed	Mdc1 modulates the interaction between TopBP1 and the MRN complex during DNA damage checkpoint responses.	TOPBP1 NBN	4.54e-05	3	136	2	27590578
Pubmed	TNF-alpha potentiates C5a-stimulated eosinophil adhesion to human bronchial epithelial cells: a role for alpha 5 beta 1 integrin.	FN1 ITGA5	4.54e-05	3	136	2	11801679
Pubmed	MMP-2, TIMP-2 and CD44v6 expression in non-small-cell lung carcinomas.	CD44 MMP2	4.54e-05	3	136	2	18265895
Pubmed	Embryonic mesodermal defects in alpha 5 integrin-deficient mice.	FN1 ITGA5	4.54e-05	3	136	2	7508365
Pubmed	A test of the role of alpha5 integrin/fibronectin interactions in tumorigenesis.	FN1 ITGA5	4.54e-05	3	136	2	9485045
Pubmed	Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin.	CSNK1D CSNK1E	4.54e-05	3	136	2	25724478
Pubmed	A novel SR-related protein specifically interacts with the carboxy-terminal domain (CTD) of RNA polymerase II through a conserved interaction domain.	POLR2A SCAF11	4.54e-05	3	136	2	9224939
Pubmed	Isolation of markers for chondro-osteogenic differentiation using cDNA library subtraction. Molecular cloning and characterization of a gene belonging to a novel multigene family of integral membrane proteins.	ITM2C ITM2A	4.54e-05	3	136	2	8702637
Pubmed	Alpha5beta1 integrin-fibronectin interactions specify liquid to solid phase transition of 3D cellular aggregates.	FN1 ITGA5	4.54e-05	3	136	2	20686611
Pubmed	A comparative study of structural and conformational properties of casein kinase-1 isoforms: insights from molecular dynamics and principal component analysis.	CSNK1D CSNK1E	4.54e-05	3	136	2	25665722
Pubmed	CRISPR-mediated gene targeting of CK1δ/ε leads to enhanced understanding of their role in endocytosis via phosphoregulation of GAPVD1.	CSNK1D CSNK1E	4.54e-05	3	136	2	32321936
Pubmed	Demonstration of catch bonds between an integrin and its ligand.	FN1 ITGA5	4.54e-05	3	136	2	19564406
Pubmed	Integrin-dependent and -independent functions of astrocytic fibronectin in retinal angiogenesis.	FN1 ITGA5	4.54e-05	3	136	2	21880786
Pubmed	Autocrine/paracrine prostaglandin E2 production by non-small cell lung cancer cells regulates matrix metalloproteinase-2 and CD44 in cyclooxygenase-2-dependent invasion.	CD44 MMP2	4.54e-05	3	136	2	12393872
Pubmed	Farnesyl diphosphate synthase exacerbates nonalcoholic steatohepatitis via the activation of AHR-CD36 axis.	CD36 AHR	4.54e-05	3	136	2	37310396
Pubmed	Sulforaphane inhibits invasion by phosphorylating ERK1/2 to regulate E-cadherin and CD44v6 in human prostate cancer DU145 cells.	CD44 MMP2	4.54e-05	3	136	2	26134113
Pubmed	Protein expression of fatty acid transporter 2 is polarized to the trophoblast basal plasma membrane and increased in placentas from overweight/obese women.	CD36 SLC27A4	4.54e-05	3	136	2	27016784
Pubmed	Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.	CSNK1D CSNK1E	4.54e-05	3	136	2	28963394
Pubmed	Human Rad17 C-terminal tail is phosphorylated by concerted action of CK1δ/ε and CK2 to promote interaction with the 9-1-1 complex.	CSNK1D CSNK1E	4.54e-05	3	136	2	31353086
Pubmed	Sequence analysis of the cDNA for the human casein kinase I delta (CSNK1D) gene and its chromosomal localization.	CSNK1D CSNK1E	4.54e-05	3	136	2	8786104
Pubmed	Co-localization of insulin-like growth factor binding protein 3 and fibronectin in human articular cartilage.	FN1 CD44	4.54e-05	3	136	2	12127836
Pubmed	ADAM9 silencing inhibits breast tumor cells transmigration through blood and lymphatic endothelial cells.	ADAM9 MMP2	4.54e-05	3	136	2	27554339
Pubmed	Implication of alpha5beta1 integrin in invasion of drug-resistant MCF-7/ADR breast carcinoma cells: a role for MMP-2 collagenase.	ITGA5 MMP2	4.54e-05	3	136	2	18707587
Pubmed	Immunohistochemical expression of CD44, matrix metalloproteinase2 and matrix metalloproteinase9 in renal cell carcinomas.	CD44 MMP2	4.54e-05	3	136	2	31053527
Pubmed	Expression and regulation of type II integral membrane protein family members in mouse male reproductive tissues.	ITM2C ITM2A	4.54e-05	3	136	2	17873332
Interaction	RHOJ interactions	MYO1D ADAM9 USP24 DOCK10 RICTOR CACHD1 ACVRL1 ITGA5 NPHP4 SDR39U1 CSNK1D CD44 ATP11A ITM2C SLC16A7 EPB41L1 MPP7	1.17e-06	633	135	17	int:RHOJ
Interaction	MYBPC2 interactions	COL12A1 FSD2 NPHP4 PA2G4 MAD2L2	1.23e-05	45	135	5	int:MYBPC2
Cytoband	8q24.13	ATAD2 KLHL38 FBXO32	1.65e-04	36	135	3	8q24.13
Cytoband	17q25	ITGB4 LGALS3BP CSNK1D	2.10e-04	39	135	3	17q25
Cytoband	7p22.2	FBXL18 SDK1	3.80e-04	10	135	2	7p22.2
GeneFamily	Beta-gamma crystallin domain containing	CRYBG2 CRYBG3	9.05e-05	3	100	2	1360
GeneFamily	Fibronectin type III domain containing	COL12A1 FN1 FSD2 ITGB4 USH2A SDK1	2.63e-04	160	100	6	555
GeneFamily	C2-set domain containing\|Immunoglobulin like domain containing\|Scavenger receptors	AGER CD36 SCARB2	4.36e-04	27	100	3	1253
GeneFamily	BRICHOS domain containing	ITM2C ITM2A	1.06e-03	9	100	2	457
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	BAZ2B SETDB2	1.61e-03	11	100	2	1025
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF28P KIF3C KIF2C	2.10e-03	46	100	3	622
GeneFamily	SH2 domain containing	SH2D1B SUPT6H HCK NCK2	2.39e-03	101	100	4	741
Coexpression	GSE32164_RESTING_DIFFERENTIATED_VS_CMYC_INHIBITED_MACROPHAGE_DN	FN1 COPG1 PRPF8 CSNK1E CD44 ATP11A ITM2C ITM2A	9.67e-06	200	135	8	M8531
Coexpression	BRUINS_UVC_RESPONSE_LATE	SIN3B COL12A1 FN1 NBN ITGB4 SDR39U1 B4GALT1 SH2D1B PA2G4 STRADA SURF2 SCARB2 MTM1 KCTD20 AHR MAD2L2 MED26 SLC16A7	2.23e-05	1136	135	18	M2247
Coexpression	TRAVAGLINI_LUNG_ADVENTITIAL_FIBROBLAST_CELL	ACVRL1 LGALS3BP B4GALT1 IGSF10 CD44 AHR MMP2 SLC16A7 ITM2A	2.39e-05	296	135	9	M41675
Coexpression	BRUINS_UVC_RESPONSE_LATE	SIN3B COL12A1 FN1 NBN ITGB4 SDR39U1 B4GALT1 SH2D1B PA2G4 STRADA SURF2 SCARB2 MTM1 KCTD20 AHR MAD2L2 MED26 SLC16A7	4.46e-05	1198	135	18	MM1062
Coexpression	JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN	POLR2A CSNK1E CD36 PLXNA2	6.47e-05	42	135	4	M16561
Coexpression	MCLACHLAN_DENTAL_CARIES_DN	TUBB2B MAGI2 ITM2A PHIP CDH12	6.68e-05	82	135	5	M1278
Coexpression	BHATTACHARYA_EMBRYONIC_STEM_CELL	IMPDH2 DTL CACHD1 MAD2L2 GNL3	7.50e-05	84	135	5	M4282
Coexpression	GSE22886_NAIVE_VS_IGG_IGA_MEMORY_BCELL_UP	RAPGEF6 SMUG1 ZNF571 LYST KCTD20 MMP2 NCK2	7.73e-05	198	135	7	M4432
Coexpression	GSE39556_CD8A_DC_VS_NK_CELL_MOUSE_3H_POST_POLYIC_INJ_DN	SIN3B BAZ2B LYST F13A1 MAGI2 CSNK1D HCK	7.98e-05	199	135	7	M9418
Coexpression	GSE44649_WT_VS_MIR155_KO_ACTIVATED_CD8_TCELL_UP	ADAM9 ZNFX1 LRRK1 LGALS3BP POGLUT1 FBXL18 ITM2C	7.98e-05	199	135	7	M9782
Coexpression	GSE33424_CD161_HIGH_VS_INT_CD8_TCELL_UP	IMPDH2 ADAM9 LRRC58 MTM1 TACSTD2 SLC16A7 HCK	8.23e-05	200	135	7	M8534
Coexpression	GSE3337_CTRL_VS_4H_IFNG_IN_CD8POS_DC_DN	NBN ZNFX1 CSNK1D CD36 CD44 SCAF11 NCK2	8.23e-05	200	135	7	M5099
Coexpression	GSE6674_PL2_3_VS_ANTI_IGM_AND_CPG_STIM_BCELL_DN	DOCK10 HEATR5A LYST B4GALT1 ABHD17B SCARB2 CD44	8.23e-05	200	135	7	M6943
Coexpression	GSE13522_CTRL_VS_T_CRUZI_Y_STRAIN_INF_SKIN_BALBC_MOUSE_DN	TUBB2B ITGA5 ADRA1B FOXP1 PRG4 ITM2A	8.56e-05	139	135	6	M2928
Coexpression	JAEGER_METASTASIS_UP	FN1 DTL TUBB2B KIF2C	9.29e-05	46	135	4	M5740
Coexpression	TRAVAGLINI_LUNG_OLR1_CLASSICAL_MONOCYTE_CELL	SLC66A2 ADAM9 MAP3K20 DOCK10 NBN ZNFX1 ITGA5 DICER1 CD44 KCTD20 AHR MAD2L2 HCK	9.75e-05	724	135	13	M41700
Coexpression	TURASHVILI_BREAST_DUCTAL_CARCINOMA_VS_DUCTAL_NORMAL_UP	FN1 DTL ZNF571 CD44	1.01e-04	47	135	4	M7585
Coexpression	KARAKAS_TGFB1_SIGNALING	FN1 KIF3C MMP2	1.03e-04	18	135	3	M17300
Coexpression	HENDRICKS_SMARCA4_TARGETS_DN	USP24 NPFFR2 IGHG1 TACSTD2	1.19e-04	49	135	4	M7914
Coexpression	BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP	COL12A1 ADAM9 ITGB4	1.43e-04	20	135	3	M45002
Coexpression	BANG_VERTEPORFIN_ENDOMETRIAL_CANCER_CELLS_UP	COL12A1 ADAM9 ITGB4	1.43e-04	20	135	3	MM1336
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CACHD1 DNAH7 IGSF10 EFHC1 BCO2 MAPK10 SDK1 PLXNA2	1.38e-07	193	135	8	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ACVRL1 ITGA5 ITGB4 CD36 MMP2 CRYBG3 PLXNA2	1.55e-07	196	135	8	a20a56d8997d6db2a10046c8801c619a379de83c
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL12A1 BAZ2B DTL ACVRL1 CD36 AHR FOXP1 ITM2A	1.81e-07	200	135	8	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	droplet-Marrow-nan-3m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 TOPBP1 DOCK10 ATAD2 LYST F13A1 SCAF11	1.41e-06	182	135	7	bc8d621be57f76d718d9b0f11e023b0f4dcb668d
ToppCell	severe_COVID-19-Plasmablast\|severe_COVID-19 / disease group, cell group and cell class (v2)	MYO1D DTL OXCT2 HPDL IGHG1 ITM2C KIF2C	1.82e-06	189	135	7	953143b2c2e87a4d8ef033a5fbb155fe62e9c78e
ToppCell	Severe-Lymphoid-T-NK\|Severe / Condition, Lineage, Cell class and cell subclass	ATAD2 BGLAP TBC1D10C SH2D1B ITM2C ITM2A KIF2C	1.88e-06	190	135	7	60642de433f84fa2cecd796c3a1a4aab9219d3db
ToppCell	10x_3'_v3-blood_(10x_3'_v3)-lymphocytic-B_lymphocytic-plasma_cell\|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYO1D DTL OXCT2 HPDL IGHG1 ITM2C KIF2C	1.95e-06	191	135	7	b23fdcd3090df9f58310b4dc8f7dc0c6d6b33226
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ACVRL1 ITGA5 ITGB4 CD36 MMP2 CRYBG3	2.09e-06	193	135	7	cc355b2ed6510619cad969ae074126d7c8db784d
ToppCell	LA\|World / Chamber and Cluster_Paper	COL12A1 FN1 MYO1D F13A1 MAPK10 PRG4 SDK1	2.09e-06	193	135	7	d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-SMC_prolif-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	COL12A1 FN1 MAP3K20 NFATC4 CD36 EPB41L1 NCK2	2.16e-06	194	135	7	78dcb9d48259afabe73b41c5508a73a8d62339a4
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 DNAH7 CD44 MAPK10 TACSTD2 SDK1 EPB41L1	2.39e-06	197	135	7	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_peribronchial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 F13A1 NPFFR2 ADRA1B NFATC4 MMP2 PRG4	2.56e-06	199	135	7	e9009eee7f77b9c9917f8e0e723001d9e76eb553
ToppCell	tumor_Lung-Fibroblasts-COL14A1+_matrix_FBs\|Fibroblasts / Location, Cell class and cell subclass	XPNPEP2 ACVRL1 LGALS3BP B4GALT1 IGHG1 MMP2 ITM2A	2.56e-06	199	135	7	0d1f2b0d10c1f8ee10c448659b2a22ea0a6a6f0d
ToppCell	tumor_Lymph_Node_/_Brain-Myeloid_cells-mo-Mac\|Myeloid_cells / Location, Cell class and cell subclass	FN1 ADAM9 F13A1 LGALS3BP SCARB2 MMP2 NENF	2.64e-06	200	135	7	195862a319794e57f0506757ae45ab70200bc5b4
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL12A1 BAZ2B DTL ACVRL1 CD36 AHR FOXP1	2.64e-06	200	135	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal1-Tpbg_(Entorhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TTC16 DTL CD44 VSIG8 HCK	5.76e-06	84	135	5	171fc90fb0d430ebf0a040c54f083aebb0e2b390
ToppCell	Hippocampus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Hpcal1-Tpbg_(Entorhinal_cortex)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TTC16 DTL CD44 VSIG8 HCK	5.76e-06	84	135	5	a087403869ee4275cb1fa4e9b0b16426dcf72a31
ToppCell	mild_COVID-19_(asymptomatic)-CD4+_T_naive\|World / disease group, cell group and cell class (v2)	RAPGEF6 CACHD1 FOXP1 C2CD6 ITM2A NCK2	8.50e-06	157	135	6	23879e65a6acc33d9aad096cd23604a77b0ac9c2
ToppCell	(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts\|(1)_Control_(PBS) / Stress and Cell class	FN1 MYO1D F13A1 BGLAP CD44 MMP2	9.47e-06	160	135	6	8450466fc2465c56798df2b520edd23c2c2e941c
ToppCell	Healthy/Control-Plasmablast\|World / Disease group and Cell class	MYO1D DTL OXCT2 HPDL IGHG1 ITM2C	1.43e-05	172	135	6	d3bfcf5d936152b71cd90f955f9331709edd979e
ToppCell	severe_influenza-Plasmablast\|severe_influenza / disease group, cell group and cell class (v2)	MYO1D OXCT2 HPDL IGSF10 IGHG1 ITM2C	1.53e-05	174	135	6	8c6c4d794373e774ecb3382cb7163b4246b98780
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYO1D CACHD1 NPFFR2 ADRA1B SH2D1B CDH12	1.53e-05	174	135	6	bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Control / Condition, Lineage and Cell class	FN1 F13A1 BGLAP FBXL18 CD36 MMP2	1.53e-05	174	135	6	4c64ff5666812fb4efa440ba4faeca51d916d68e
ToppCell	Healthy/Control-Plasmablast\|Healthy/Control / Disease group and Cell class	MYO1D DTL OXCT2 HPDL IGHG1 ITM2C	1.53e-05	174	135	6	97d19ef3240a1f648c6befaabb9ce45ad469cbce
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	F13A1 BGLAP IGSF10 BCO2 ITM2C MMP2	1.53e-05	174	135	6	e5f12831187140e84b9a49e93b2376b9fefb1aec
ToppCell	Influenza_Severe-Plasmablast\|Influenza_Severe / Disease group and Cell class	MYO1D OXCT2 HPDL IGSF10 ITM2C KIF2C	1.58e-05	175	135	6	3f9b9793d3d1b7a9b97899272b6a0d37b05c11d1
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|normal_Lymph_Node / Location, Cell class and cell subclass	LRRK1 ITGB4 B4GALT1 IGSF10 SCARB2 ITM2C	1.58e-05	175	135	6	29fbdfe1d3bfcb063be2bced0128a33176c5b78f
ToppCell	343B-Lymphocytic-NK_cells-NK_cell_D3\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	F13A1 BGLAP IGSF10 BCO2 ITM2C MMP2	1.63e-05	176	135	6	bd5c85b3a4fb88ffe156599f6d224aa7664a513a
ToppCell	Control-Myeloid-MoAM2,_CCL18\|Myeloid / Condition, Lineage and Cell class	FN1 XPNPEP2 F13A1 BGLAP CD36 MMP2	1.68e-05	177	135	6	470f54fe2b21c7350ea471e02039461a3808f700
ToppCell	Endothelial-Endothelial-C\|Endothelial / shred on cell class and cell subclass (v4)	TUBB2B DICER1 SDR39U1 CD36 CD44 FOXP1	1.68e-05	177	135	6	b5b9278dfd76b1aacd88e5fe86e91a2c9b565f87
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 DOCK10 FOXP1 CRYBG3 SLC16A7 MPP7	1.79e-05	179	135	6	e6ae070b4c52ba08167c7d64ea4cfbac0454c1bf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 DOCK10 BCO2 FOXP1 CRYBG3 MPP7	1.91e-05	181	135	6	30729f0364f719c044712a51453e22dc2c1a232b
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|(2)_5-FU / Stress and Cell class	FN1 MYO1D BGLAP IGSF10 CD44 MMP2	1.91e-05	181	135	6	56ae86072858c156681507aecd1bc6cb0a3372d2
ToppCell	droplet-Marrow-nan-3m-Myeloid-nan\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 DOCK10 LYST F13A1 FOXP1 SCAF11	1.97e-05	182	135	6	f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IMPDH1 FN1 ACVRL1 LGALS3BP FOXP1 ITM2A	1.97e-05	182	135	6	ef65b095f4240d61cfd4a59aec19d72d324dba1d
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	IMPDH1 FN1 ACVRL1 LGALS3BP FOXP1 ITM2A	1.97e-05	182	135	6	97a805783a1f2b055c21307db250e3688674eff3
ToppCell	COVID-19-kidney-CD-IC-A\|kidney / Disease (COVID-19 only), tissue and cell type	CPAMD8 DOCK10 FOXP1 CRYBG3 SLC16A7 MPP7	2.03e-05	183	135	6	5c7597a5b2bf6a481ca2c7e68560179214150fa0
ToppCell	(2)_5-FU-(4)_COL2.3+_osteoblasts\|World / Stress and Cell class	FN1 MYO1D BGLAP IGSF10 MMP2 ITM2A	2.09e-05	184	135	6	684d05340a3dfb8aa08b881516a37f9627a10448
ToppCell	Control-Epithelial-Club\|Epithelial / Disease state, Lineage and Cell class	CPAMD8 HELB ADRA1B ST6GALNAC3 AHR FBXO32	2.16e-05	185	135	6	6814b3c94c7558443c038a227b5c8563d2cfeac4
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DOCK10 CACHD1 ATAD2 FBXO32 ITM2A NCK2	2.16e-05	185	135	6	847257d232b9993cad50c814fd4ffeef52385295
ToppCell	droplet-Marrow-nan-3m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 DOCK10 LYST F13A1 FOXP1 SCAF11	2.16e-05	185	135	6	7adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 DOCK10 FOXP1 CRYBG3 SLC16A7 MPP7	2.16e-05	185	135	6	9438097e94219c1db922b8507e3a29106d32a923
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_ADARB2_ADAM33\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL12A1 DOCK10 ADRA1B CD36 SDK1 CCDC152	2.29e-05	187	135	6	02105c82a9ba79d2f19e002188377fc3440770c2
ToppCell	mild_COVID-19-Plasmablast\|World / disease group, cell group and cell class (v2)	MYO1D OXCT2 HPDL IGHG1 ITM2C KIF2C	2.36e-05	188	135	6	9a5ba6abdc307402301dae25db2a5f3e0d576417
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	COL12A1 MYO1D AGER ATP11A TACSTD2 PLXNA2	2.36e-05	188	135	6	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	severe_COVID-19-Plasmablast\|World / disease group, cell group and cell class (v2)	MYO1D OXCT2 HPDL IGHG1 ITM2C KIF2C	2.36e-05	188	135	6	25ca19af4ac419a0f5026a6ccbd8b554b268a6f3
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 FN1 ACVRL1 ITGA5 ITGB4 ST6GALNAC3	2.43e-05	189	135	6	12b6f1c3bf526b90e112374bf937701f645c5780
ToppCell	IPF-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	LYST SH2D1B STRADA ST6GALNAC3 SLC16A7 RGL4	2.43e-05	189	135	6	5c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 FN1 ACVRL1 ITGA5 ITGB4 ST6GALNAC3	2.51e-05	190	135	6	bf9bc57a605c7e3979bc4f7260e6fb92c3eb8690
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	FN1 F13A1 BGLAP PRG4 SDK1 EPB41L1	2.51e-05	190	135	6	d2afa08ad868acc6fce308ec21b0bf93591d4010
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CPAMD8 CACHD1 CD36 ATP11A MAPK10 MPP7	2.58e-05	191	135	6	34cc997e4e5c727495f321e6807a84aa124da486
ToppCell	(2)_Fibroblasts-(21)_Fibro-2\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	FN1 F13A1 CD44 PRG4 SDK1 EPB41L1	2.58e-05	191	135	6	5ee353c79055c08e8a3e2b43a0345bceb09f3890
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ANO4 DOCK10 GALNT13 ADRA1B SDK1 CCDC152	2.66e-05	192	135	6	025fac36b862f9ca7f96fb4a1946c44ba7cbc382
ToppCell	PND07\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 LRRC58 IGSF10 ADRA1B CD44 MMP2	2.66e-05	192	135	6	8171a60df481195c39a7f740effcae8e4deb6ca7
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma-early_osteoblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	COL12A1 FN1 LGALS3BP PLA2R1 MMP2 FBXO32	2.74e-05	193	135	6	5e46a9f65e85aca78f825fdef88a95b97eec8743
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CPAMD8 FN1 ACVRL1 ITGA5 ITGB4 ST6GALNAC3	2.74e-05	193	135	6	0b328f725f6feba263783eaca60c142e80df90f3
ToppCell	E16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DTL ATAD2 IGSF10 PA2G4 MMP2 GNL3	2.82e-05	194	135	6	af4bbb2deb5a3913eb58990690fc3c62fbc3708c
ToppCell	PBMC-Mild-Lymphocyte-B-Plasmablast-Plasmablast-Developping_Plasmablast\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYO1D DTL HPDL IGHG1 ITM2C KIF2C	2.82e-05	194	135	6	5a519538327029ad2b880ef9647e2ac6ab3961a4
ToppCell	droplet-Limb_Muscle-nan-21m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 IGSF10 CD44 MMP2 PRG4 NENF	2.90e-05	195	135	6	d2c9c58b46bf96f9a536e177b995e340b55c6750
ToppCell	Mild/Remission-B_naive-8\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	BAZ2B LYST CSNK1D FOXP1 ITM2C HCK	2.90e-05	195	135	6	0a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCell	COPD-Lymphoid-T\|COPD / Disease state, Lineage and Cell class	RAPGEF6 HELB FBXO32 ITM2A MPP7 NCK2	2.98e-05	196	135	6	30e53b8050d2a041f855d0e39bbd8f923c64c489
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-Z\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FN1 MAP3K20 F13A1 CD36 CD44 AHR	2.98e-05	196	135	6	7dff78ff7b2b333680de1c9ca78190770574d796
ToppCell	T_cells-GZMK+GZMB+_T_cells\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	TTC16 DTL TBC1D10C ITM2A KIF2C RGL4	2.98e-05	196	135	6	b237287def04def371191b054a41ec0b3150da75
ToppCell	Influenza-Influenza_Severe-Lymphocyte-B-Plasmablast\|Influenza_Severe / Disease, condition lineage and cell class	MYO1D OXCT2 HPDL IGSF10 ITM2C KIF2C	3.07e-05	197	135	6	9108edafbf5744ed65f556bcbbf819a9b71176a9
ToppCell	ILEUM-inflamed-(5)_Plasma-(5)_IgG_plasma_cells\|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	FN1 LGALS3BP IGHG1 ITM2C KIF3C MMP2	3.07e-05	197	135	6	6b0941883e40bd82c65659b97a4752e8e32ac190
ToppCell	Caecum-B_cell-B_cell_IgG_Plasma\|B_cell / Region, Cell class and subclass	TTC16 IGHG1 ITM2C TACSTD2 GNL3 EPB41L1	3.07e-05	197	135	6	40c8ff067e8242e2ca083ea04cd6026168191a97
ToppCell	10x5'-Liver-Lymphocytic_T_CD4\|Liver / Manually curated celltypes from each tissue	RAPGEF6 LGALS3BP CD44 AHR FOXP1 NCK2	3.07e-05	197	135	6	4891111894b741555f549deec6af8006376d9358
ToppCell	Control-Stromal-Fibroblast\|Stromal / Disease state, Lineage and Cell class	B4GALT1 CD44 AHR MMP2 SLC16A7 ITM2A	3.07e-05	197	135	6	64cc5f61c88e9560b0f8f6f3151255dffb5c3d66
ToppCell	COVID-19-Fibroblasts-Intermediate_pathological_FB\|COVID-19 / group, cell type (main and fine annotations)	COL12A1 FN1 MAGI2 PLA2R1 MMP2 SDK1	3.07e-05	197	135	6	f1c8936986123a3151140c374fcd62d6705c530b
ToppCell	distal-3-Epithelial-Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CACHD1 ITGB4 NPFFR2 FBXO32 TACSTD2 ZG16	3.07e-05	197	135	6	72ac9068cfd8f04c521a858d55eb8b5764de0282
ToppCell	control-Myeloid-Non-resident_Macrophage\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	KDM3B ITGA5 F13A1 SCARB2 CD44 KCTD20	3.07e-05	197	135	6	df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 HELB TBC1D10C CD44 FBXO32 NCK2	3.16e-05	198	135	6	f486747f2c96b403bdeee0dfe0cc2679ffeefa33
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BAZ2B LYST F13A1 CD36 AHR HCK	3.16e-05	198	135	6	a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCell	Mild_COVID-19-T/NK\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	HELB TBC1D10C ITM2C SLC16A7 ITM2A RGL4	3.16e-05	198	135	6	329eb0fc0bda3d66765de0393290dccb3e15c311
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-mesenchymal_stem_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 FN1 IGSF10 MMP2 ITM2A NENF	3.16e-05	198	135	6	1b90d632e59c3c47b936e829cceeb0334f05f34f
ToppCell	severe-HLA-DR+_CD83+_Monocyte\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	BAZ2B LYST F13A1 CD36 AHR ATP11A	3.16e-05	198	135	6	d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCell	distal-Epithelial-Basal-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CACHD1 ITGB4 NPFFR2 FBXO32 TACSTD2 ZG16	3.16e-05	198	135	6	dda0bf3a48f738df590ce23b891d82be19e10d66
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ACVRL1 ITGA5 ITGB4 MMP2 CRYBG3	3.16e-05	198	135	6	5e781583908c4ee107d986904a646a7c6b8e3591
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 FN1 IGSF10 MMP2 ITM2A NENF	3.16e-05	198	135	6	524305c5d7b1d53e86ec0af775efefa3e0955e47
ToppCell	Severe_COVID-19-Myeloid-MoAM3\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	MAP3K20 ITGA5 F13A1 CD36 CD44 HCK	3.25e-05	199	135	6	30523cf08815ca214877e33a2c52197ff8318557
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANO4 FN1 BAZ2B MAP3K20 MMP2 FBXO32	3.25e-05	199	135	6	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ACVRL1 ITGA5 ITGB4 MMP2 CRYBG3	3.25e-05	199	135	6	9b02acae6325b0ac9642438a4431285ff396e5fe
ToppCell	Fibroblasts-HLA-DRA_high_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	LGALS3BP B4GALT1 NFATC4 IGHG1 AHR MMP2	3.25e-05	199	135	6	fcbb3a9c0f4c5b4c1f09db24b9f50cc1166fa43b
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP3K20 ITGA5 F13A1 CD36 CD44 HCK	3.25e-05	199	135	6	b2dc3d0af6ecd3ab01779aaa1f061cb0f941cae8
ToppCell	343B-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FN1 IGSF10 CD36 CD44 MMP2 PRG4	3.25e-05	199	135	6	212e89d097753790061310373a1fafba773488b6
ToppCell	343B-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	FN1 IGSF10 CD36 CD44 MMP2 PRG4	3.25e-05	199	135	6	14b676aa289c0578a37be32cec3ea285c79d97cc
ToppCell	(02)_MMP9/10+-(1)_GFP\|(02)_MMP9/10+ / shred by cell type by condition	FN1 ITGA5 ITGB4 B4GALT1 CSNK1E MMP2	3.25e-05	199	135	6	448ba982be804007f991d469eca9d885b21ae499
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	MAP3K20 ITGA5 F13A1 CD36 CD44 HCK	3.25e-05	199	135	6	105709b97c55826a852aed27658e3b4af1738c8a
ToppCell	Mild_COVID-19-T/NK-CD8+_T\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	HELB TBC1D10C ITM2C SLC16A7 ITM2A RGL4	3.25e-05	199	135	6	27a1b62e270cad1defa80f04f4ee5b5c8e448792
ToppCell	droplet-Limb_Muscle-nan-3m-Mesenchymal-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL12A1 IGSF10 ITM2C MMP2 PRG4 NENF	3.25e-05	199	135	6	edd5300da1a3b758210ff8f949e9d1988b8bc7e2
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM3\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MAP3K20 ITGA5 F13A1 CD36 CD44 HCK	3.25e-05	199	135	6	0892957a49304ce4b6daa3657d76d8365ce0dd19
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-Mesoderm_2_(ZEB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 FN1 BAZ2B MMP2 MAPK10 ITM2A	3.25e-05	199	135	6	da016849b804fbf80edbfa8f8f56c9df8bbf2d51
ToppCell	(02)_MMP9/10+\|World / shred by cell type by condition	COL12A1 FN1 ITGA5 ITGB4 CD44 MMP2	3.25e-05	199	135	6	3f78eddeaa67d3b767aa38de765632166b09a4f0
ToppCell	BAL-Severe-Myeloid-MoAM-MoAM3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MAP3K20 ITGA5 F13A1 CD36 CD44 HCK	3.25e-05	199	135	6	961ad44199871be8e09d31904d383edc865ba262
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-immature_mesenchymal_cell\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL12A1 FN1 BAZ2B MMP2 MAPK10 ITM2A	3.25e-05	199	135	6	3cf62666ffd000427fdbb7cf940793f98c3ed29c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FN1 DOCK10 ZNFX1 ITGA5 CD44 AHR	3.25e-05	199	135	6	379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell	Parenchymal-10x3prime_v2-Immune_Lymphocytic-T-T_CD4-CD4\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK10 HELB TBC1D10C CD44 FBXO32 NCK2	3.25e-05	199	135	6	5fc9bd5740e2e4d657c8c3dd26567db9a6da5af8
ToppCell	Parenchyma_COVID-19-Endothelial-TX-Artery\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CPAMD8 ACVRL1 ITGA5 ITGB4 ST6GALNAC3 ITM2A	3.34e-05	200	135	6	34b279804475ea58fbb052b96f44128c082627a9
ToppCell	Lung_Parenchyma-Severe-Endothelial-Endothelial-Artery\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CPAMD8 ACVRL1 ITGA5 ITGB4 ST6GALNAC3 ITM2A	3.34e-05	200	135	6	8552cc7a439449b30b59760c3e8667217b9852b5
ToppCell	Control_saline-Endothelial-Endothelial-Gen_Cap\|Control_saline / Treatment groups by lineage, cell group, cell type	BAZ2B DTL ACVRL1 CD36 AHR FOXP1	3.34e-05	200	135	6	3b97920e1e6e2f09ddba2a861baa9c00c2970f4c
Drug	1-phenyl-2-pyrrolidinone	FN1 ITGA5 MMP2	1.98e-06	5	134	3	CID000078375
Drug	p-Nitrophenyl alpha-D-xyloside	FN1 ITGA5 PTPN5 SCARB2 CD44	4.14e-06	41	134	5	CID000082482
Drug	AC1NRBPT	FN1 ITGA5 HPDL F11 BGLAP AGER MMP2 MAPK10	5.39e-06	162	134	8	CID005288571
Drug	PPAPs	CD36 SCARB2 SLC27A4	1.09e-05	8	134	3	CID009576869
Drug	1,4-Aptd	IMPDH1 IMPDH2 LYST	1.09e-05	8	134	3	CID000152126
Drug	MIV-210	IMPDH1 IMPDH2 SMUG1	1.09e-05	8	134	3	CID000072183
Drug	Laminin peptide 11	FN1 ITGA5 CD36	1.63e-05	9	134	3	CID000219027
Drug	ecgonine methyl ester	IMPDH1 IMPDH2 LIPE AHR MMP2 FBXO32	1.64e-05	91	134	6	CID000104904
Drug	cryptolepine	ACVRL1 ADRA1B PHIP	2.32e-05	10	134	3	CID000082143
Drug	hydroxymethylphosphonate	IMPDH1 IMPDH2	3.44e-05	2	134	2	CID000075795
Drug	6-Chloropurine Riboside, 5'-Monophosphate	IMPDH1 IMPDH2	3.44e-05	2	134	2	DB03948
Drug	Mycophenolate mofetil	IMPDH1 IMPDH2	3.44e-05	2	134	2	DB00688
Drug	purinogen	IMPDH1 IMPDH2	3.44e-05	2	134	2	CID003081226
Drug	AC1L9X6T	IMPDH1 IMPDH2	3.44e-05	2	134	2	CID000477594
Drug	Mycophenolic acid	IMPDH1 IMPDH2	3.44e-05	2	134	2	DB01024
Drug	LMWH	CPAMD8 COL12A1 FN1 IMPDH2 ADAM9 POLR2A PRPF8 F11 CSNK1D CSNK1E CD36 CD44 MMP2 PRG4	3.77e-05	663	134	14	CID000000772
Disease	Alzheimer's disease (is_marker_for)	NBN PTPN5 SLC8A2 CSNK1D CSNK1E AGER CD36 MMP2 MAPK10	1.70e-06	257	126	9	DOID:10652 (is_marker_for)
Disease	end stage renal disease (is_marker_for)	FN1 BGLAP AGER MMP2	4.50e-05	46	126	4	DOID:783 (is_marker_for)
Disease	Sturge-Weber syndrome (is_marker_for)	FN1 MMP2	5.41e-05	3	126	2	DOID:0111563 (is_marker_for)
Disease	breast ductal carcinoma (is_implicated_in)	RICTOR CD44	5.41e-05	3	126	2	DOID:3007 (is_implicated_in)
Disease	atherosclerosis (biomarker_via_orthology)	AGER CD36 MMP2	8.22e-05	20	126	3	DOID:1936 (biomarker_via_orthology)
Disease	ferritin measurement	FN1 BAZ2B B4GALT1 C2CD6 GNL3	1.62e-04	119	126	5	EFO_0004459
Disease	squamous cell carcinoma	AHR FOXP1 ATP11A EPB41L1	1.97e-04	67	126	4	EFO_0000707
Disease	atrial fibrillation (is_marker_for)	AGER CD36 MMP2	3.44e-04	32	126	3	DOID:0060224 (is_marker_for)
Disease	syndromic X-linked intellectual disability Najm type (implicated_via_orthology)	CSNK1D CSNK1E	3.75e-04	7	126	2	DOID:0060807 (implicated_via_orthology)
Disease	vitamin D-binding protein measurement	NPFFR2 IGHG1 ST6GALNAC3	4.90e-04	36	126	3	EFO_0005675
Disease	colorectal cancer (is_marker_for)	KDM3B RICTOR DICER1 MMP2 KIF2C	5.82e-04	157	126	5	DOID:9256 (is_marker_for)
Disease	retinitis pigmentosa (is_implicated_in)	IMPDH1 PRPF8 USH2A	7.20e-04	41	126	3	DOID:10584 (is_implicated_in)
Disease	Pancreatic Neoplasm	CD44 AHR FOXP1 MMP2	9.06e-04	100	126	4	C0030297
Disease	pancreatic cancer (is_marker_for)	ADAM9 AGER AHR MMP2	9.40e-04	101	126	4	DOID:1793 (is_marker_for)
Disease	Malignant neoplasm of pancreas	CD44 AHR FOXP1 MMP2	9.75e-04	102	126	4	C0346647
Disease	Retinitis Pigmentosa	IMPDH1 PRPF8 AHR USH2A	1.05e-03	104	126	4	C0035334
Disease	Centriacinar Emphysema	AGER MMP2	1.16e-03	12	126	2	C0221227
Disease	Panacinar Emphysema	AGER MMP2	1.16e-03	12	126	2	C0264393
Disease	Focal Emphysema	AGER MMP2	1.16e-03	12	126	2	C2350878
Disease	Neoplasm Invasiveness	FN1 ITGA5 AHR FOXP1 MMP2	1.19e-03	184	126	5	C0027626
Disease	Ciliopathies	IMPDH1 NPHP4 WDR35 USH2A	1.29e-03	110	126	4	C4277690
Disease	Hypertensive disease	FN1 F11 CD36 AHR MMP2	1.37e-03	190	126	5	C0020538
Disease	intracranial aneurysm (biomarker_via_orthology)	AGER MMP2	1.37e-03	13	126	2	DOID:10941 (biomarker_via_orthology)
Disease	caudate volume change measurement	GALNT13 NFATC4	1.59e-03	14	126	2	EFO_0021491
Disease	diabetic retinopathy (is_marker_for)	F13A1 AGER MMP2	1.61e-03	54	126	3	DOID:8947 (is_marker_for)
Disease	Rhabdomyosarcoma	NBN DICER1	1.83e-03	15	126	2	C0035412
Disease	vision disorder	MAGI2 SDK1	2.09e-03	16	126	2	MONDO_0021084
Disease	response to cranial radiation therapy, short-term memory	MAP3K20 CACHD1 FOXP1	2.18e-03	60	126	3	EFO_0004335, EFO_0010950
Disease	Disorder of eye	IMPDH1 ADAM9 PRPF8 NPHP4 USH2A	2.21e-03	212	126	5	C0015397
Disease	Pulmonary Emphysema	AGER MMP2	2.36e-03	17	126	2	C0034067
Disease	Vitiligo	CD44 FOXP1	2.36e-03	17	126	2	C0042900
Disease	Astrocytosis	ITGA5 ITGB4	2.36e-03	17	126	2	C3887640
Disease	Gliosis	ITGA5 ITGB4	2.36e-03	17	126	2	C0017639
Disease	level of Sphingomyelin (d34:1) in blood serum	USP24 NPFFR2	2.65e-03	18	126	2	OBA_2045175
Disease	Congenital Fiber Type Disproportion	MAP3K20 MTM1	2.65e-03	18	126	2	C0546264
Disease	Hypertrophy	AGER AHR	2.65e-03	18	126	2	C0020564
Disease	type 2 diabetes mellitus (is_marker_for)	BGLAP LIPE CD36 MMP2	2.80e-03	136	126	4	DOID:9352 (is_marker_for)
Disease	hypertension (biomarker_via_orthology)	FN1 HDAC8 AGER CD36 MMP2	2.96e-03	227	126	5	DOID:10763 (biomarker_via_orthology)
Disease	anorexia nervosa	MYO1D FOXP1 PHIP	3.38e-03	70	126	3	MONDO_0005351
Disease	Contact Dermatitis	CD44 AHR KIF2C	3.52e-03	71	126	3	C0011616
Disease	Contact hypersensitivity	CD44 AHR KIF2C	3.52e-03	71	126	3	C0162351
Disease	polycystic ovary syndrome (biomarker_via_orthology)	ADRA1B MMP2	3.60e-03	21	126	2	DOID:11612 (biomarker_via_orthology)
Disease	periodontitis (biomarker_via_orthology)	AGER MMP2	3.60e-03	21	126	2	DOID:824 (biomarker_via_orthology)
Disease	gastric ulcer (biomarker_via_orthology)	F13A1 MMP2	3.60e-03	21	126	2	DOID:10808 (biomarker_via_orthology)
Disease	Retinitis pigmentosa	IMPDH1 PRPF8 USH2A	3.95e-03	74	126	3	cv:C0035334

Protein segments in the cluster

Peptide	Gene	Start	Entry
YKNGRPDYIIVTQRP	AHR	371	P35869
RVKYGEQTPRTNYQI	C2orf16	101	Q68DN1
VQRYPLYTQITVDIG	B4GALT1	381	P15291
YDQPLYVGSAELKRR	CNTNAP1	911	P78357
PAVYIRIKNRAQGEY	CRYBG3	2836	Q68DQ2
RQYPEVIKYLSRNGI	BAZ2B	781	Q9UIF8
TYIVRRYIATPNGVL	CACHD1	726	Q5VU97
YLDIGNNPRVGTKRY	ACVRL1	361	P37023
GVRYSLQYPTLVTRR	ADRA1B	146	P35368
LRQRKATVYYQAPLE	ATAD2	296	Q6PL18
RKNYTAYRQEPIASK	DTL	246	Q9NZJ0
YILVYRKSNPQTEKR	ANO4	121	Q32M45
DSTVLKTRGNPYRYE	C7orf31	191	Q8N865
YVQSKGRARAPISNY	DICER1	546	Q9UPY3
VEKRTGQLLPGRYYS	BCO2	336	Q9BYV7
RSVSKEYYNQTGRIP	ACTR10	371	Q9NZ32
KNQITYRIIGYTPDL	MMP2	121	P08253
SNYRVRVYQIPGKPE	AGER	111	Q15109
YYRVRLNSQNKTSPV	NPFFR2	291	Q9Y5X5
RPIVNGEEGYRYIVN	IQCM	451	A0A1B0GVH7
EYDIPGLVRKNRYKT	PTPN5	316	P54829
GQRTTIYKRDPSKQY	PA2G4	241	Q9UQ80
SYNVTRRKGYDQIIP	POGLUT1	371	Q8NBL1
RSNFYIKIRPGEYEQ	EPB41L1	331	Q9H4G0
LYVREVYPVGIFQKR	MAD2L2	31	Q9UI95
YEKSRAIYESRQQVP	MAGI2	746	Q86UL8
QPTVRNYVENRPKYA	MAPK10	291	P53779
VYQSRRGPLVKYSSD	LGALS3BP	431	Q08380
NRTGYVPSNYVERKN	NCK2	46	O43639
VIYRARYQGQPVAVK	LRRK1	1256	Q38SD2
IKRRPGGRSEVIYNY	KCTD20	331	Q7Z5Y7
RPQATAVYKVSEYAR	IMPDH2	341	P12268
RPYTAPEVNKQRESY	C2CD6	571	Q53TS8
AVGYKRPISQYARVA	KIF3C	681	O14782
VYKNVPYSQRPRAVD	PLXNA2	1536	O75051
PYRENKNLTGTARYA	CSNK1D	166	P48730
TVGPIRRRYSDKYNV	FOXP1	431	Q9H334
EVTPYRRQTNEKYRL	MPP7	356	Q5T2T1
KYPIVGYTARRILNE	NENF	136	Q9UMX5
QTLRKRLYEEYGVQG	KDM3B	1656	Q7LBC6
GLIANSKYIRPRIQY	SLC16A7	301	O60669
RVEYVIGRYPQENKG	F13A1	101	P00488
QEKLLTYYRNRAAIP	MIEF1	136	Q9NQG6
ENLRESQPYRYTVKA	ITGB4	1286	P16144
RYRPRDYTVNLDGQV	MED26	396	O95402
LTTYRKPVDGDNYVR	RICTOR	851	Q6R327
AARTIKIRNISYTPY	LRRC58	266	Q96CX6
VNKRITYTNPYPSRR	NPHP4	1346	O75161
AYYQQPGKERQIRAA	HPDL	286	Q96IR7
RPQGTAVYKVAEYAR	IMPDH1	341	P20839
VKRGTYLPQTYIIQE	ITM2C	186	Q9NQX7
EGSEVVKRPRRYLYQ	BGLAP	41	P02818
SQIPRRYYSLGEIRN	GALNT13	421	Q8IUC8
DGRPQEVGRVYVYLQ	ITGA5	356	P08648
VYYQPPQRSSFRIKL	RGL4	76	Q8IZJ4
PLQTGDVIYLVYRKN	CHFR	96	Q96EP1
ATRKEGYIPSNYVAR	HCK	121	P08631
RILQVTPKDQGYYRC	IGSF10	631	Q6WRI0
YGSPLKTPSVVYRQR	HEATR5A	656	Q86XA9
KYEQYSGDIRQLPRA	DOCK10	126	Q96BY6
DGTRYVQKGEYRTNP	CD44	151	P16070
ASGRVQKYRITYQPS	COL12A1	1776	Q99715
VLQYRVVYSPVDGTR	COL12A1	1961	Q99715
LPGRKYIVNVYQISE	FN1	781	P02751
SNIQVKQRGPYTYRV	CD36	81	P16671
IRGEQVKIPLSVYNY	CPAMD8	816	Q8IZJ3
QRVGSLYPIKQRRVY	CRYBG2	1516	Q8N1P7
TGAQQNYARKYTIPI	DNAH7	3886	Q8WXX0
YQDSTVLPQSIYRRK	CCDC152	201	Q4G0S7
QRERPGVYTNVVEYV	F11	601	P03951
REAPRPYSKQVSYVI	ADAM9	56	Q13443
AQYTIYEPVIRLKGQ	LYST	1751	Q99698
YAAAVRRPQVPIKYQ	MAP3K20	611	Q9NYL2
GRYLPQTYVVREDLV	ITM2A	186	O43736
LSYRNGYAIVRRPTV	EFHC1	31	Q5JVL4
ARQVVLKYTVPGYRN	GNL3	346	Q9BVP2
GYSRRQQELYFLPVV	CDH12	556	P55289
KTKPREEQYNSTYRV	IGHG1	171	P01857
TTNPSKYIRFIYNRV	COPG1	466	Q9Y678
RYVNYIKTSEVVRLP	EMC7	121	Q9NPA0
KVIPQRTLATGYQYS	SDR39U1	266	Q9NRG7
KGRYYSVNVPIQDGI	HDAC8	221	Q9BY41
VRCYPRKEQYGDTLQ	FBXO32	301	Q969P5
EYQKLGPIRYQEIVT	SLC13A1	336	Q9BZW2
RKTLPADVQNYYSRR	SCAF11	1151	Q99590
YKDAISISRLQNPRY	SDK1	421	Q7Z5N4
NQPCYRKLGLEVYVT	KIF2C	386	Q99661
VQVKPVVGSRSYQYQ	HELB	91	Q8NG08
KRGTQIGYRIYDLPN	KIF28P	721	B7ZC32
RGTPRDISKAVLYYQ	DELE1	291	Q14154
VYYAQRLLVTNRPGV	LIPE	426	Q05469
EKPNGIIINYFIYRR	USH2A	3891	O75445
NLARYKPTGEYVTVR	STRADA	86	Q7RTN6
DTYEPNYGTVKQRVL	RAPGEF6	1441	Q8TEU7
ERLNSVKTRPEYYVG	TDRD6	1336	O60522
PEYSNKRVSRPVQVY	NFATC4	651	Q14934
YRLLTGVEYVVGRKN	NBN	16	O60934
VRGEPLQVERTLIYY	TACSTD2	246	P09758
RLAPGYINQEVVRLY	FBXL18	236	Q96ME1
QLQPGRSYIIYVRAL	FSD2	531	A1L4K1
RPLRTHYGYINVKTQ	ST6GALNAC3	56	Q8NDV1
RIGSSYRALPKTYQQ	SIN3B	396	O75182
VGPYTYRELRNKANI	SCARB2	86	Q14108
VLAIKYTDIRGQPRY	TCP1	176	P17987
PELQVYTRGKKYQRL	SURF2	41	Q15527
IRIQYSPARLAYQDK	PRG4	1316	Q92954
PNTLEYGNRTYKIIN	PLA2R1	1116	Q13018
VPNIYVDRVIKGQKY	OXCT2	261	Q9BYC2
GYYRIQTAEGSPKQV	SH2D1B	61	O14796
RYGIRPENVIIYGQS	ABHD17B	156	Q5VST6
IPQRYPDNRIVSSKY	ATP11A	41	P98196
QPLRDSRKYVNGSTY	PRPF8	211	Q6P2Q9
YQPRGKPRIEYVTVT	SUPT6H	1476	Q7KZ85
VKAQNPGVYTRITKY	PRSS45P	211	Q7RTY3
TTGYKYKRLQRQIPT	SETDB2	326	Q96T68
YKRLQRQIPTGIYEC	SETDB2	331	Q96T68
GYPTQNVSRSLRRKY	VSIG8	346	P0DPA2
NGPIKGRVYITNYRL	MTM1	56	Q13496
NGKYRLERLVPTAVY	PHIP	156	Q8WWQ0
QKGRYVPLDQEAYSR	SLC27A4	621	Q6P1M0
NYIRKVQQVSEGAPY	TTI2	491	Q6NXR4
LQVLKAYTLYRPEQG	TBC1D10C	161	Q8IV04
VRRGNSQYPGAKYII	POLR2A	406	P24928
YNEATGNKYVPRAIL	TUBB2B	51	Q9BVA1
QRSYTAPDKTGIRVY	SOGA1	1001	O94964
RNYVTRYCQGPKEVL	SMUG1	66	Q53HV7
RGVLREQYLQKYISP	ZNFX1	741	Q9P2E3
DGPITALRVRVNTYY	ZG16	46	O60844
KVYDQTNPYTDVRRR	USP24	2016	Q9UPU5
TVPLKVREYYSRGQQ	TTC16	56	Q8NEE8
YTGPKERVIKTQYQS	ERVK-19	481	Q9WJR5
RYYQTIREKVGPELQ	XPNPEP2	616	O43895
IVRYTKEVYVPHPRN	MRPL27	96	Q9P0M9
IQRYSLPNVGLIQKY	WDR35	526	Q9P2L0
IYQGRPNDTNREYKS	TOPBP1	946	Q92547
SYIQHQRIQTGEKPY	ZNF571	181	Q7Z3V5
VPYVPQYRDIRRTQN	SLC66A2	31	Q8N2U9
PYRENKNLTGTARYA	CSNK1E	166	P49674
GYTRRILAYDPQSNK	KLHL38	486	Q2WGJ6
VVSVNPYKLLNIYGR	MYO1D	46	O94832
PYKLLNIYGRDTIEQ	MYO1D	51	O94832
VYKRYRTDPRSGIII	SLC8A2	256	Q9UPR5