Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Pubmed	Impaired tamoxifen metabolism reduces survival in familial breast cancer patients.	CYP2D6 BRCA2	3.12e-06	3	36	2	18794105
Pubmed	Clustering of Genetic Anomalies of Cilia Outer Dynein Arm and Central Apparatus in Patients with Transposition of the Great Arteries.	DNAH9 HYDIN	6.24e-06	4	36	2	36140829
Pubmed	Cyclic nucleotides converge on brown adipose tissue differentiation.	ROCK1 INSR	6.24e-06	4	36	2	20068229
Pubmed	An investigation into the human serum "interactome".	SAFB2 JARID2 GDF10 CLU	2.38e-05	162	36	4	15174051
Pubmed	In vitro fertilization causes epigenetic modifications to the onset of gene expression from the zygotic genome in mice.	PAFAH1B3 INSR	3.73e-05	9	36	2	11159375
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	SAFB2 ROCK1 PDCD2 PRPF8 GNE CLU	5.16e-05	653	36	6	33742100
Pubmed	Association of DNA repair and steroid metabolism gene polymorphisms with clinical late toxicity in patients treated with conformal radiotherapy for prostate cancer.	CYP2D6 BRCA2	2.60e-04	23	36	2	16638864
Pubmed	Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.	DNAH9 HYDIN	6.07e-04	35	36	2	37890489
Pubmed	The protein interaction landscape of the human CMGC kinase group.	ROCK1 HIPK4 PRPF8 CLU INSR	7.09e-04	695	36	5	23602568
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	SAFB2 PRPF8	9.59e-04	44	36	2	26471122
Disease	1-stearoyl-GPC (18:0) measurement	MFSD2A FADS1	1.81e-05	6	33	2	EFO_0800217
Disease	1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement	ROCK1 FADS1	7.95e-05	12	33	2	EFO_0800453
Disease	level of Phosphatidylcholine (16:1_18:1) in blood serum	ROCK1 FADS1	9.39e-05	13	33	2	OBA_2045082
Disease	level of Phosphatidylcholine (14:0_18:2) in blood serum	ROCK1 FADS1	1.63e-04	17	33	2	OBA_2045063
Disease	Acute Confusional Senile Dementia	CYP2D6 CLU INSR	1.86e-04	99	33	3	C0546126
Disease	Alzheimer's Disease, Focal Onset	CYP2D6 CLU INSR	1.86e-04	99	33	3	C0750900
Disease	Alzheimer Disease, Early Onset	CYP2D6 CLU INSR	1.86e-04	99	33	3	C0750901
Disease	Presenile dementia	CYP2D6 CLU INSR	1.86e-04	99	33	3	C0011265
Disease	Alzheimer Disease, Late Onset	CYP2D6 CLU INSR	1.86e-04	99	33	3	C0494463
Disease	Familial Alzheimer Disease (FAD)	CYP2D6 CLU INSR	1.91e-04	100	33	3	C0276496
Disease	Alzheimer's Disease	CYP2D6 CLU INSR	1.97e-04	101	33	3	C0002395
Disease	level of Phosphatidylcholine (16:1_18:2) in blood serum	ROCK1 FADS1	2.51e-04	21	33	2	OBA_2045083
Disease	Drug habituation	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C0013170
Disease	Substance-Related Disorders	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C0236969
Disease	Drug abuse	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C0013146
Disease	Drug Use Disorders	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C0013222
Disease	Drug Dependence	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C1510472
Disease	Substance Dependence	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C0038580
Disease	Substance Use Disorders	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C0038586
Disease	Organic Mental Disorders, Substance-Induced	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C0029231
Disease	Prescription Drug Abuse	CYP2D6 FARP1 INSR	2.89e-04	115	33	3	C4316881
Disease	Substance abuse problem	CYP2D6 FARP1 INSR	2.96e-04	116	33	3	C0740858
Disease	Kartagener Syndrome	DNAH9 HYDIN	7.05e-04	35	33	2	C0022521
Disease	Polynesian Bronchiectasis	DNAH9 HYDIN	7.05e-04	35	33	2	C4317124
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	DNAH9 HYDIN	7.05e-04	35	33	2	C4551906

Protein segments in the cluster

Peptide	Gene	Start	Entry
HKEHNHPSFYRERTP	C2orf16	1536	Q68DN1
TDALFHEFLRHDPHF	CBARP	546	Q8N350
HEFLRHDPHFDDTPA	CBARP	551	Q8N350
DEPFRPVQAKFEFHH	C6orf62	136	Q9GZU0
EHFAHPPSEVKMHFA	CFAP36	206	Q96G28
HPRAHFLDADPGFVH	PAFAH1B3	166	Q15102
HPDKNHHPRAEEAFK	DNAJC14	471	Q6Y2X3
HHFFKRNPHPDAANP	HIPK4	246	Q8NE63
LDERPPRAHAQHFHK	GDF10	306	P55107
DHLDHIIPDHNFLFP	PDCD2	176	Q16342
SFIHRFGKHAPHVVP	OR51B4	256	Q9Y5P0
FHVVHTPPLHPDFKR	PRF1	181	P14222
ASEPVKDADPHFHHF	GLYR1	206	Q49A26
KDDLHPSFPEVSFFH	INSR	1291	P06213
FHLKQPHFHGTEPIF	MFSD2A	426	Q8NA29
HLPFLPSPEFHDYHH	FAXDC2	266	Q96IV6
HFPVSFHADKRVLHE	HYDIN	1621	Q4G0P3
EHHPNFRAVKHVPFD	GNE	271	Q9Y223
FVPPFKTKSHFHRVE	BRCA2	2406	P51587
EHHAFFRLFEEPKPK	FARP1	311	Q9Y4F1
KPFRFHPEHFLDAQG	CYP2D6	411	P10635
HPEHFLDAQGHFVKP	CYP2D6	416	P10635
RPASGHFHLLRHKPF	FNDC1	811	Q4ZHG4
SPHHKLHLFENPAFS	CRYBB3	111	P26998
DFKSSLLPHLPVHFH	DNAAF9	606	Q5TEA3
HFQHHAKPNCFRKDP	FADS1	216	O60427
FHKEAPFRFDSIHPH	DNAH9	1241	Q9NYC9
RKFHEKHHSHREFPF	HTN1	31	P15515
TENDHHKFHPLPRFE	JARID2	741	Q92833
RKEPHKPPFFNHSFE	MINAR1	291	Q9UPX6
KHPVRFFVHKRPHVD	CTDNEP1	101	O95476
HFHSPAFQHPPTEFI	CLU	261	P10909
PKEFYHEVHRPSHFL	PRPF8	2301	Q6P2Q9
HVAGRHHPDVFAEFF	USP35	66	Q9P2H5
HPLSSRPFSALHDFH	HIVEP3	2151	Q5T1R4
ADFPRPDHRFHDFDH	SAFB2	756	Q14151
HKGHEFIPTLYHFPA	ROCK1	1226	Q13464
FLFLTHFNTHPRFHP	TMEM187	241	Q14656
KFHMSHEPFIFHEVG	ZNF776	156	Q68DI1