Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontriplex DNA binding

DDX12P DDX11

6.83e-054682GO:0045142
GeneOntologyMolecularFunctionglucuronosyltransferase activity

UGT2B4 UGT2B7 UGT2B11

2.29e-0435683GO:0015020
GeneOntologyBiologicalProcessbiphenyl catabolic process

UGT2B4 UGT2B7 UGT2B11

1.81e-068673GO:0070980
GeneOntologyBiologicalProcessbiphenyl metabolic process

UGT2B4 UGT2B7 UGT2B11

3.87e-0610673GO:0018879
GeneOntologyBiologicalProcessxenobiotic glucuronidation

UGT2B4 UGT2B7 UGT2B11

7.06e-0612673GO:0052697
GeneOntologyBiologicalProcesscellular glucuronidation

UGT2B4 UGT2B7 UGT2B11

4.18e-0521673GO:0052695
GeneOntologyBiologicalProcessglucuronate metabolic process

UGT2B4 UGT2B7 UGT2B11

8.07e-0526673GO:0019585
GeneOntologyBiologicalProcessuronic acid metabolic process

UGT2B4 UGT2B7 UGT2B11

8.07e-0526673GO:0006063
GeneOntologyCellularComponentnuclear membrane

RASA1 OSBPL3 UGT2B4 TERB1 UGT2B7 ACKR2 UGT2B11

1.38e-04349687GO:0031965
GeneOntologyCellularComponentnuclear outer membrane

UGT2B4 UGT2B7 UGT2B11

2.98e-0440683GO:0005640
GeneOntologyCellularComponentCtf18 RFC-like complex

DDX12P DDX11

4.61e-0410682GO:0031390
GeneOntologyCellularComponentdynein complex

DYNC2LI1 DYNLT5 DNAH11

7.25e-0454683GO:0030286
MousePhenoabnormal chromosome number

PTPN11 DDX12P SPI1 DDX11 CEP63

2.34e-0586565MP:0004023
MousePhenoabnormal germ layer morphology

TBX3 PTPN11 DDX12P TENM4 DYNC2LI1 DDX11

4.29e-05161566MP:0014138
MousePhenoimpaired somite development

PTPN11 DDX12P TENM4 RASA1 DDX11

5.85e-05104565MP:0009768
MousePhenoabnormal embryonic tissue morphology

JAK3 TRIM45 TBX3 TRIT1 PTPN11 DDX12P TENM4 RASA1 DYNC2LI1 PCSK6 SOWAHB TXNDC12 DNAH11 DDX11

9.47e-0511165614MP:0002085
MousePhenoabnormal chromosome morphology

PTPN11 DDX12P SPI1 DDX11 CEP63

1.45e-04126565MP:0003702
MousePhenoabnormal mesoderm morphology

PTPN11 DDX12P TENM4 DYNC2LI1 DDX11

1.51e-04127565MP:0014141
MousePhenoabnormal inferior vena cava morphology

TRIM45 TBX3 PSME4 DNAH11

1.55e-0468564MP:0006063
MousePhenoabnormal heart looping

TBX3 DDX12P DYNC2LI1 PCSK6 DDX11

2.01e-04135565MP:0000269
MousePhenoabnormal somite development

PTPN11 DDX12P TENM4 RASA1 TXNDC12 DDX11

2.51e-04222566MP:0001688
MousePhenoabnormal vena cava morphology

TRIM45 TBX3 PSME4 DNAH11

2.52e-0477564MP:0006062
DomainRhs_assc_core

TENM4 TENM2

3.68e-053662IPR022385
DomainUDPGT

UGT2B4 UGT2B7 UGT2B11

5.36e-0521663PF00201
DomainUDPGT

UGT2B4 UGT2B7 UGT2B11

5.36e-0521663PS00375
DomainUDP_glucos_trans

UGT2B4 UGT2B7 UGT2B11

5.36e-0521663IPR002213
DomainTox-GHH_dom

TENM4 TENM2

7.35e-054662IPR028916
DomainTen_N

TENM4 TENM2

7.35e-054662IPR009471
DomainTen_N

TENM4 TENM2

7.35e-054662PF06484
DomainTENEURIN_N

TENM4 TENM2

7.35e-054662PS51361
DomainTox-GHH

TENM4 TENM2

7.35e-054662PF15636
DomainYD

TENM4 TENM2

1.22e-045662IPR006530
Domain6-blade_b-propeller_TolB-like

TENM4 EIF3B TENM2

5.74e-0446663IPR011042
DomainNHL

TENM4 TENM2

9.36e-0413662PS51125
DomainPLAC

PCSK6 ADAMTS18

1.09e-0314662PF08686
DomainCarboxyPept-like_regulatory

TENM4 TENM2

1.62e-0317662IPR008969
DomainPLAC

PCSK6 ADAMTS18

2.02e-0319662PS50900
DomainPLAC

PCSK6 ADAMTS18

2.02e-0319662IPR010909
PathwayKEGG_ASCORBATE_AND_ALDARATE_METABOLISM

MIOX UGT2B4 UGT2B7 UGT2B11

1.68e-0625504M605
PathwayREACTOME_PREDNISONE_ADME

UGT2B4 UGT2B7 UGT2B11

7.07e-0523503MM16639
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B11

8.06e-0524503MM14599
PathwayREACTOME_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B11

9.14e-0525503M17787
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B11

9.14e-0525503MM15820
PathwayWP_GLUCURONIDATION

UGT2B4 UGT2B7 UGT2B11

1.03e-0426503M39404
PathwayKEGG_PENTOSE_AND_GLUCURONATE_INTERCONVERSIONS

UGT2B4 UGT2B7 UGT2B11

1.29e-0428503M19580
PathwayREACTOME_PARACETAMOL_ADME

UGT2B4 UGT2B7 UGT2B11

3.51e-0439503MM15695
PathwayKEGG_PORPHYRIN_AND_CHLOROPHYLL_METABOLISM

UGT2B4 UGT2B7 UGT2B11

4.07e-0441503M7399
PathwayREACTOME_ASPIRIN_ADME

UGT2B4 UGT2B7 UGT2B11

5.02e-0444503M45014
PathwayREACTOME_ASPIRIN_ADME

UGT2B4 UGT2B7 UGT2B11

5.36e-0445503MM15694
Pubmed

Weak activity of UDP-glucuronosyltransferase toward Bisphenol analogs in mouse perinatal development.

UGT2B4 UGT2B7 UGT2B11

2.49e-07768326074487
Pubmed

Hetero-oligomer formation of mouse UDP-glucuronosyltransferase (UGT) 2b1 and 1a1 results in the gain of glucuronidation activity towards morphine, an activity which is absent in homo-oligomers of either UGT.

UGT2B4 UGT2B7 UGT2B11

3.98e-07868332093886
Pubmed

Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.

TRIT1 LIMA1 PTPN11 TENM4 PTPRG OSBPL3 SVIL ANKRD52 CEP63

1.01e-0653668915840001
Pubmed

Exchangeable gene trap using the Cre/mutated lox system.

TRIT1 LIMA1 PTPN11 TENM4 PTPRG OSBPL3 SVIL ANKRD52 CEP63

1.04e-0653868910512203
Pubmed

Expression of UDP-glucuronosyltransferases (UGTs) 2B7 and 1A6 in the human brain and identification of 5-hydroxytryptamine as a substrate.

UGT2B4 UGT2B7

3.77e-06268210222050
Pubmed

Substrate specificity of the human UDP-glucuronosyltransferase UGT2B4 and UGT2B7. Identification of a critical aromatic amino acid residue at position 33.

UGT2B4 UGT2B7

3.77e-06268217263731
Pubmed

Warsaw Breakage Syndrome associated DDX11 helicase resolves G-quadruplex structures to support sister chromatid cohesion.

DDX12P DDX11

3.77e-06268232855419
Pubmed

Nuclear-cytoplasmic translocation of SQSTM1/p62 protein enhances ESCC cell migration and invasion by stabilizing EPLIN expression.

LIMA1 SQSTM1

3.77e-06268238185251
Pubmed

Localization of chi1-related helicase genes to human chromosome regions 12p11 and 12p13: similarity between parts of these genes and conserved human telomeric-associated DNA.

DDX12P DDX11

3.77e-0626828833153
Pubmed

Single nucleotide polymorphisms and haplotype frequencies of UGT2B4 and UGT2B7 in a Japanese population.

UGT2B4 UGT2B7

3.77e-06268215319348
Pubmed

Characterization of putative human homologues of the yeast chromosome transmission fidelity gene, CHL1.

DDX12P DDX11

3.77e-0626829013641
Pubmed

Vti1b promotes TRPV1 sensitization during inflammatory pain.

LIMA1 DOCK11 OSBPL3 EIF3B TXNDC12

5.20e-0612768530335684
Pubmed

Isolation of a human YAC contig encompassing a cluster of UGT2 genes and its regional localization to chromosome 4q13.

UGT2B4 UGT2B7

1.13e-0536827835904
Pubmed

Ski can negatively regulates macrophage differentiation through its interaction with PU.1.

HDAC3 SPI1

1.13e-05368217621263
Pubmed

cDNA cloning and expression of two new members of the human liver UDP-glucuronosyltransferase 2B subfamily.

UGT2B4 UGT2B11

1.13e-0536828333863
Pubmed

Clopidogrel Carboxylic Acid Glucuronidation is Mediated Mainly by UGT2B7, UGT2B4, and UGT2B17: Implications for Pharmacogenetics and Drug-Drug Interactions .

UGT2B4 UGT2B7

1.13e-05368229138287
Pubmed

Loss of ChlR1 helicase in mouse causes lethality due to the accumulation of aneuploid cells generated by cohesion defects and placental malformation.

DDX12P DDX11

1.13e-05368217611414
Pubmed

SHP-2 is involved in heterodimer specific loss of phosphorylation of Tyr771 in the PDGF beta-receptor.

PTPN11 RASA1

1.13e-05368211896619
Pubmed

Mammalian ChlR1 has a role in heterochromatin organization.

DDX12P DDX11

1.13e-05368221854770
Pubmed

Methadone inhibits CYP2D6 and UGT2B7/2B4 in vivo: a study using codeine in methadone- and buprenorphine-maintained subjects.

UGT2B4 UGT2B7

1.13e-05368222092298
Pubmed

Mouse ten-m/Odz is a new family of dimeric type II transmembrane proteins expressed in many tissues.

TENM4 TENM2

2.25e-05468210225957
Pubmed

Autophagy controls centrosome number by degrading Cep63.

SQSTM1 CEP63

2.25e-05468227869116
Pubmed

Contribution of polymorphisms in UDP-glucuronosyltransferase and CYP2D6 to the individual variation in disposition of carvedilol.

UGT2B4 UGT2B7

2.25e-05468216849011
Pubmed

Localization of the insulin-like growth factor I receptor binding sites for the SH2 domain proteins p85, Syp, and GTPase activating protein.

PTPN11 RASA1

2.25e-0546827642582
Pubmed

All four members of the Ten-m/Odz family of transmembrane proteins form dimers.

TENM4 TENM2

2.25e-05468212000766
Pubmed

The vitamin K-dependent anticoagulant factor, protein S, inhibits multiple VEGF-A-induced angiogenesis events in a Mer- and SHP2-dependent manner.

PTPN11 MERTK

2.25e-05468223065156
Pubmed

UDP-glucuronosyltransferase and sulfotransferase polymorphisms, sex hormone concentrations, and tumor receptor status in breast cancer patients.

UGT2B4 UGT2B7

3.75e-05568215318931
Pubmed

Phosphotyrosine-independent binding of a 62-kDa protein to the src homology 2 (SH2) domain of p56lck and its regulation by phosphorylation of Ser-59 in the lck unique N-terminal region.

RASA1 SQSTM1

3.75e-0556828618896
Pubmed

Immunoaffinity profiling of tyrosine phosphorylation in cancer cells.

JAK3 LIMA1 PTPN11 RASA1 SQSTM1 EIF3B

4.42e-0532768615592455
Pubmed

TBX3 is overexpressed in breast cancer and represses p14 ARF by interacting with histone deacetylases.

HDAC3 TBX3

5.62e-05668218245468
Pubmed

Requirement of phospholipase C gamma, the tyrosine phosphatase Syp and the adaptor proteins Shc and Nck for PDGF-induced DNA synthesis: evidence for the existence of Ras-dependent and Ras-independent pathways.

PTPN11 RASA1

5.62e-0566828890167
Pubmed

HDAC3 is negatively regulated by the nuclear protein DBC1.

HDAC3 BRINP1

7.86e-05768221030595
Pubmed

The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with expression implying distinct yet overlapping developmental roles.

TENM4 TENM2

7.86e-05768210625539
Pubmed

The murine Ten-m/Odz genes show distinct but overlapping expression patterns during development and in adult brain.

TENM4 TENM2

7.86e-05768212915301
Pubmed

Genome wide molecular analysis of minimally differentiated acute myeloid leukemia.

PTPN11 RASA1

7.86e-05768219773259
Pubmed

The ENU-induced cetus mutation reveals an essential role of the DNA helicase DDX11 for mesoderm development during early mouse embryogenesis.

DDX12P DDX11

1.05e-04868222678773
Pubmed

Disposition of flavonoids via enteric recycling: enzyme stability affects characterization of prunetin glucuronidation across species, organs, and UGT isoforms.

UGT2B4 UGT2B7

1.05e-04868218052087
Pubmed

Mapping homologs of Drosophila odd Oz (odz): Doc4/Odz4 to mouse chromosome 7, Odz1 to mouse chromosome 11; and ODZ3 to human chromosome Xq25.

TENM4 TENM2

1.05e-04868210331952
Pubmed

Guanosine triphosphatase-activating protein-associated protein, but not src-associated protein p68 in mitosis, is a part of insulin signaling complexes.

RASA1 SQSTM1

1.05e-0486829564850
Pubmed

Polymorphic gene regulation and interindividual variation of UDP-glucuronosyltransferase activity in human small intestine.

UGT2B4 UGT2B7

1.05e-04868210748067
Pubmed

The configuration of the 17-hydroxy group variably influences the glucuronidation of beta-estradiol and epiestradiol by human UDP-glucuronosyltransferases.

UGT2B4 UGT2B7

1.05e-04868218719240
Pubmed

Associations between polymorphisms in glucuronidation and sulfation enzymes and mammographic breast density in premenopausal women in the United States.

UGT2B4 UGT2B7

1.05e-04868220142249
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

HDAC3 LIMA1 DOCK11 GPR158 OSBPL3 SPHKAP SVIL SLC4A4 TENM2

1.05e-0496368928671696
Pubmed

A novel role for Gab1 and SHP2 in epidermal growth factor-induced Ras activation.

PTPN11 RASA1

1.34e-04968215574420
Pubmed

Potential target genes of EMX2 include Odz/Ten-M and other gene families with implications for cortical patterning.

ADPRH TENM4 TENM2

1.39e-045168316919471
Pubmed

SUMO-specific protease 1 is critical for early lymphoid development through regulation of STAT5 activation.

JAK3 SPI1

1.68e-041068222284677
Pubmed

Cartography of teneurin and latrophilin expression reveals spatiotemporal axis heterogeneity in the mouse hippocampus during development.

TENM4 TENM2

1.68e-041068238713721
Pubmed

Role of UDP-glucuronosyltransferase isoforms in 13-cis retinoic acid metabolism in humans.

UGT2B4 UGT2B7

2.45e-041268220308471
Pubmed

Detoxification enzyme polymorphisms are not involved in duodenal adenomatosis in familial adenomatous polyposis.

UGT2B4 UGT2B7

2.45e-041268218161889
Pubmed

Genetic variants in TPMT and COMT are associated with hearing loss in children receiving cisplatin chemotherapy.

UGT2B4 UGT2B7 UGT2B11

3.00e-046668319898482
Pubmed

PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.

LIMA1 SMPDL3B SQSTM1 TERB1 EIF3B SBSN

3.44e-0447768631300519
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

TENM4 GPR158 SQSTM1 SPHKAP EIF3B SLC4A4 SNAP47 TENM2 TXNDC12

3.65e-04113968936417873
Pubmed

Phosphoprotein associated with glycosphingolipid-enriched microdomains (PAG), a novel ubiquitously expressed transmembrane adaptor protein, binds the protein tyrosine kinase csk and is involved in regulation of T cell activation.

PTPN11 RASA1

3.89e-041568210790433
Pubmed

Meta-analysis of genome-wide association studies identifies common variants associated with blood pressure variation in east Asians.

TBX3 PTPN11

4.44e-041668221572416
Pubmed

The P-body component USP52/PAN2 is a novel regulator of HIF1A mRNA stability.

LIMA1 SMPDL3B SQSTM1 SVIL EIF3B

4.64e-0432868523398456
Pubmed

ATF4 May Be Essential for Adaption of the Ocular Lens to Its Avascular Environment.

SQSTM1 BFSP2

5.03e-041768237998373
Pubmed

Protein tyrosine phosphatases expression during development of mouse superior colliculus.

PTPN11 PTPRG

5.03e-041768219727691
Pubmed

Gene expression profiling at early organogenesis reveals both common and diverse mechanisms in foregut patterning.

TBX3 SLC4A4

5.03e-041768221924257
Pubmed

The chemokine CCL1 triggers an AMFR-SPRY1 pathway that promotes differentiation of lung fibroblasts into myofibroblasts and drives pulmonary fibrosis.

PTPN11 RASA1

5.65e-041868234407391
Pubmed

Phase II metabolism of hesperetin by individual UDP-glucuronosyltransferases and sulfotransferases and rat and human tissue samples.

UGT2B4 UGT2B7

5.65e-041868220056724
Pubmed

CUEDC2, a novel interacting partner of the SOCS1 protein, plays important roles in the leukaemogenesis of acute myeloid leukaemia.

JAK3 PTPN11 RASA1

6.74e-048768329991678
Pubmed

Glomerulocystic kidney disease in mice with a targeted inactivation of Wwtr1.

DYNC2LI1 DNAH11

7.00e-042068217251353
Pubmed

A quantitative protein interaction network for the ErbB receptors using protein microarrays.

JAK3 PTPN11 RASA1

7.44e-049068316273093
Pubmed

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection.

HDAC3 SQSTM1

7.72e-042168222190037
Pubmed

Transcriptional Repression of Aerobic Glycolysis by OVOL2 in Breast Cancer.

HDAC3 LIMA1 SVIL

8.70e-049568335896951
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

TENM4 GPR158 KDM3B HPS5

1.00e-0322568412168954
Pubmed

Global genetic analysis in mice unveils central role for cilia in congenital heart disease.

PSME4 PCSK6 DNAH11

1.01e-0310068325807483
Pubmed

The ability of inner-cell-mass cells to self-renew as embryonic stem cells is acquired following epiblast specification.

JAK3 TBX3 PCSK6

1.01e-0310068324859004
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SPHKAP DCLK3 SENP7

1.07e-0310268311214970
Pubmed

Chromatin regulation by Brg1 underlies heart muscle development and disease.

HDAC3 TBX3

1.10e-032568220596014
Pubmed

Murine craniofacial development requires Hdac3-mediated repression of Msx gene expression.

HDAC3 TBX3

1.19e-032668223506836
Pubmed

Identification of new ciliary signaling pathways in the brain and insights into neurological disorders.

TENM4 GPR158 BRINP1 SLC4A4 TXNDC12

1.19e-0340568538187761
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

TENM4 ZNF644 SPHKAP TENM2 SENP7

1.22e-0340768512693553
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

SPHKAP SLC4A4 SNAP47

1.33e-0311068327889896
Pubmed

Novel interactors and a role for supervillin in early cytokinesis.

LIMA1 SVIL

1.38e-032868220309963
Pubmed

A neomorphic cancer cell-specific role of MAGE-A4 in trans-lesion synthesis.

LIMA1 SQSTM1 SVIL

1.62e-0311868327377895
Pubmed

Nkx2-5 regulates cardiac growth through modulation of Wnt signaling by R-spondin3.

TBX3 TENM4

1.69e-033168225053429
Pubmed

Use of RDA analysis of knockout mice to identify myeloid genes regulated in vivo by PU.1 and C/EBPalpha.

SPI1 FCN2

1.80e-03326829611252
Pubmed

SRC Homology 2 Domain Binding Sites in Insulin, IGF-1 and FGF receptor mediated signaling networks reveal an extensive potential interactome.

PTPN11 RASA1

1.80e-033268222974441
Pubmed

Analysis of mouse embryonic patterning and morphogenesis by forward genetics.

DDX12P DDX11

1.91e-033368215755804
Pubmed

Quantitative interactome proteomics identifies a proteostasis network for GABAA receptors.

LIMA1 SQSTM1 SVIL

1.92e-0312568336030824
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

WDR33 SQSTM1 ANKRD52

1.92e-0312568329467281
InteractionDYNLT5 interactions

LIMA1 SVIL DYNLT5

4.34e-0610683int:DYNLT5
CytobandEnsembl 112 genes in cytogenetic band chr4q13

UGT2B4 UGT2B7 SLC4A4 UGT2B11

9.04e-05157684chr4q13
Cytoband4q13

UGT2B4 UGT2B7

2.24e-04156824q13
Cytoband3p22.2

TTC21A DCLK3

5.84e-04246823p22.2
CytobandEnsembl 112 genes in cytogenetic band chr3p22

TTC21A DCLK3 ACKR2

2.62e-03184683chr3p22
GeneFamilyUDP glucuronosyltransferases

UGT2B4 UGT2B7 UGT2B11

8.25e-0532483363
CoexpressionLAKE_ADULT_KIDNEY_C11_THIN_ASCENDING_LIMB

TENM4 PTPRG OSBPL3 PCSK6 SVIL UGT2B7

5.17e-06169686M39230
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 AGBL3 DNAH11

7.19e-06175685284fdc7a9d303636a637041846850d19d114861a
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM232 MORN1 TTC21A DYNLT5 DNAH11

8.02e-061796855e5f1cdf4aa66868d45b74ba91e20e848a3cbaff
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 AGBL3 DNAH11

8.46e-061816856a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBX3 TENM4 TMEM232 DYNLT5 DNAH11

8.46e-061816853aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBX3 TENM4 TMEM232 DYNLT5 DNAH11

8.46e-06181685997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell3'-Distal_airway-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADPRH STXBP2 SPI1 DOCK11 TERB1

8.46e-06181685166ff44fcc0a2943b7f485ea8a9c314964e013bb
ToppCell5'-Adult-Appendix-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TBX3 TENM4 TMEM232 DYNLT5 DNAH11

8.46e-06181685e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCellIPF-Myeloid-Macrophage_Alveolar|IPF / Disease state, Lineage and Cell class

STXBP2 PSME4 SPI1 DOCK11 SVIL

1.07e-05190685e539ebc0f4c5ee5dba86c614387be7d91338ad47
ToppCellwk_08-11-Mesenchymal-Fibroblast-Mesenchymal_3|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TENM4 DOCK11 SVIL ADAMTS18 BRINP1

1.13e-05192685d88753b200d9c8da6716222d697ddf0a1548d6c8
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5--L5-6|Neuronal / cells hierarchy compared to all cells using T-Statistic

DOCK11 OSBPL3 PCSK6 SVIL DYNLT5

1.37e-052006858c1d4fffa5abe89ee2ff84fed2dfa97c779bde04
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5-|Neuronal / cells hierarchy compared to all cells using T-Statistic

DOCK11 OSBPL3 PCSK6 SVIL DYNLT5

1.37e-052006851026b4ede4ea61d01ea942164b37a08c8c8234ff
ToppCellLung_Parenchyma-Control|Lung_Parenchyma / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STXBP2 SPI1 DOCK11 SVIL LRPAP1

1.37e-052006852cb0fba2477d885b62850e473b4b637a5af531a9
ToppCellNeuronal-Inhibitory-iB-iB_2(PVALB)-LGR5|Neuronal / cells hierarchy compared to all cells using T-Statistic

DOCK11 OSBPL3 PCSK6 SVIL DYNLT5

1.37e-0520068572c9cd872074b60f62685a95eab83c41e609eb6e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 UGT2B7 AGBL3 DNAH11

8.84e-05153684d6526d17826470534b766df144c74e73eb83fdad
ToppCelldroplet-Fat-SCAT-30m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 SPI1 DOCK11 ANKRD52

8.84e-051536842731c3d4ac40ecc22108f8f3f45a069077159125
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)-|356C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS18 BRINP1 ACKR2 DOC2B

1.21e-041666845ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell356C-Endothelial_cells-Endothelial-F_(Lymphatics)|356C / Donor, Lineage, Cell class and subclass (all cells)

ADAMTS18 BRINP1 ACKR2 DOC2B

1.21e-041666846bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-SPN_Neuron_STR|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B GPR158 TENM2 DOC2B

1.27e-04168684b87fc63f9e35dfcfc46cb129ea569e73c5e018bb
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-medium_spiny_neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SMPDL3B GPR158 TENM2 DOC2B

1.27e-04168684b96a48552f4236a95bbcdce2f1b05041086d7101
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related|GW23 / Sample Type, Dataset, Time_group, and Cell type.

HDAC3 LIMA1 HPS5 DNAH11

1.30e-0416968429db25e7c5f31d98a08a35d7ec5ade203242bc50
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM232 TTC21A DYNLT5 DNAH11

1.30e-04169684fba841664939c771881ba97f14ef1df6635c04ff
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-OPC_related-Oligodendrocyte/OPC|GW23 / Sample Type, Dataset, Time_group, and Cell type.

HDAC3 LIMA1 HPS5 DNAH11

1.30e-04169684b1611e61f635f8f9b87250e026ad30999cbee041
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 UGT2B7 BRINP1 DNAH11

1.33e-041706845d5f208682be21ed58320f5fc083a7898f8712da
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBX3 ADAMTS18 DYNLT5 SLC4A4

1.33e-041706845570c0e825bca77613bf0ebde620cf744fa1cb84
ToppCellnormal_Lung-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

MIOX DYNC2LI1 RALGPS1 ZNF644

1.39e-041726840657c736f3c52d25cf7f652eac005ddcde9232ef
ToppCell3'-Distal_airway-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TMEM232 TTC21A DYNLT5 DNAH11

1.42e-04173684c3762655caa79ac4879876f470d32578a3c93b01
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 DNAH11

1.52e-04176684327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellwk_20-22-Hematologic-Myeloid-Promyelocyte-like|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

STXBP2 SPI1 KDM3B EIF3B

1.52e-04176684ee33d7077a92c1fd371081e7c990c7266e711957
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 DNAH11

1.55e-04177684da8802a6351d3e510822f82e2fde8a4314a2216e
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 UGT2B7 AGBL3 DNAH11

1.58e-04178684c20f050344a2e120e685e2a7fe36c6dfc1dc37b6
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADPRH STXBP2 SPI1 MIOX

1.62e-04179684ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_FAM150B|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK11 OSBPL3 SVIL DYNLT5

1.69e-04181684af92b8b7f455210dab502ef6964f3a0162180759
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRG DOCK11 UGT2B7 BRINP1

1.69e-041816849d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 DNAH11

1.72e-041826845e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRG DOCK11 UGT2B7 BRINP1

1.72e-04182684eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

TENM4 STXBP2 SVIL LRPAP1

1.72e-04182684a035d45fd512bee8dac38eb387dbf39f5a8a1fed
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5-6_PVALB_STON2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK11 OSBPL3 PCSK6 DYNLT5

1.72e-04182684a3c5c0eff527c8d3848acda14af8f9e99c69b0de
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 DNAH11

1.76e-04183684cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCelldroplet-Kidney-nan-18m|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PSME4 MIOX SQSTM1 SLC4A4

1.80e-04184684e02859bbac36dbbd55d7ae8cb5e46b764d7c6381
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 DNAH11

1.80e-04184684da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCellILEUM-inflamed-(5)_Plasma-(5)_IgM_plasma_cells|(5)_Plasma / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

WDR33 PCSK6 ACKR2 DDX11

1.83e-0418568426ea60b6392410fab048f2e406a9860a018429cc
ToppCellControl-Myeloid-Macrophage_Alveolar|World / Disease state, Lineage and Cell class

PSME4 SPI1 DOCK11 SVIL

1.83e-0418568485cb81759589a26d83676cffbf2bc37399683c10
ToppCellNS-moderate-d_16-33-Epithelial-Ciliated|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMEM232 TTC21A DYNLT5 DNAH11

1.83e-041856845e689c2fb36ce3ac2adc8d15f67107f21cf68868
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TBX3 TENM4 SPHKAP SLC4A4

1.83e-041856843b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell5'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTPRG DCLK3 ADAMTS18 DNAH11

1.87e-041866846568358812f0ca4e0161a1a1b29682fbced35c79
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_A_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK11 SPHKAP ADAMTS18 DNAH11

1.87e-041866844bb54043f944a979db91bde9a86dd66f498c7658
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK11 OSBPL3 DYNLT5 SLC4A4

1.87e-041866846379609b7ace80683f5754b16aa77f11b43766ae
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l25-31|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

DYNC2LI1 PCSK6 ANKRD52 SBSN

1.91e-04187684fa8f221b4c2df61eadaa9c77e4cf45848b00330b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PTPRG DOCK11 OSBPL3 UGT2B7

1.91e-04187684c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

TMEM232 TTC21A DYNLT5 DNAH11

1.95e-041886846833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 DNAH11

1.95e-0418868463a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

TMEM232 TTC21A DYNLT5 DNAH11

1.95e-041886845ba5cbb403518026e9040379fb5d99339ea977d8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK11 DYNC2LI1 UGT2B7 DNAH11

1.99e-04189684904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellIPF-Epithelial-Basal|Epithelial / Disease state, Lineage and Cell class

LIMA1 PTPRG SVIL SLC4A4

2.03e-041906844f15842b424eefadbfe451875e517cf70e29607f
ToppCellIPF-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

STXBP2 PSME4 DOCK11 SVIL

2.03e-041906842592765016f291565697265800a232b2edef3792
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPHKAP BRINP1 MERTK TENM2

2.03e-041906841bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOCK11 OSBPL3 DYNLT5 SLC4A4

2.03e-041906848c9c230a509afaeee50644153974a5642b01a2b8
ToppCellfacs-Thymus-Epithelium-24m-Epithelial|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHKAP PCSK6 RNF217 TENM2

2.07e-04191684eec14997d2bfc7e6b5a601afc43a147f6b96d668
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-TECs|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHKAP PCSK6 RNF217 TENM2

2.07e-041916841730ec5dc1cfd2f0cba7e21555641c7bce97e09d
ToppCellControl-Myeloid|Control / group, cell type (main and fine annotations)

MAN1A1 SPI1 DOCK11 MERTK

2.07e-041916849c4acc5f3c2f9c0c5520863bb22f391774372347
ToppCellfacs-Thymus-Epithelium-24m-Epithelial-epithelial_cell_of_thymus|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHKAP PCSK6 RNF217 TENM2

2.07e-041916844b77abc68bd72c64e7062f9527fe9d9605289ceb
ToppCellControl-Myeloid-Macrophage_Alveolar|Myeloid / Disease state, Lineage and Cell class

LIMA1 PSME4 DOCK11 SVIL

2.07e-04191684a7bb8aba9c59c037d995a77928cc7b4d5cbb82b9
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TBX3 PTPRG SLC4A4 TENM2

2.11e-041926844c9d748f209cc1e13d28c8c7f5180ab8522e0fbf
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SPHKAP BRINP1 MERTK TENM2

2.11e-0419268425460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCellControl-Myeloid-Monocyte-derived_macrophages|Control / group, cell type (main and fine annotations)

MAN1A1 SPI1 DOCK11 MERTK

2.16e-04193684a6b3bd01e585e2e3fbe9bf693a2e385773123f8e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 GPR158 SPHKAP TENM2

2.16e-04193684461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TENM4 GPR158 SPHKAP TENM2

2.16e-041936840dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TMEM232 RALGPS1 UGT2B7 SLC4A4

2.16e-041936843866667dd221612589ae50f5c52f73a183a49ce6
ToppCellCOVID-19-Heart-Macrophage|Heart / Disease (COVID-19 only), tissue and cell type

MAN1A1 SPI1 DOCK11 MERTK

2.20e-04194684f09675cd472200363c458952f00d2e41990800ee
ToppCellMesenchymal_cells-Endosteal_fibro.|Mesenchymal_cells / Lineage and Cell class

MAN1A1 PCSK6 ACKR2 SBSN

2.20e-041946849a4b5de4d1d8a0aa76fed7b36548ea628f3009cc
ToppCellnormal_Lung|World / Location, Cell class and cell subclass

MAN1A1 STXBP2 SPI1 SVIL

2.20e-04194684affae83d7f982d18117f5b95705f09809f304b0b
ToppCellCTRL-Myeloid-Alveolar_Macrophage|CTRL / Disease state, Lineage and Cell class

SPI1 DOCK11 SVIL LRPAP1

2.20e-04194684be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAN1A1 SPI1 DOCK11 MERTK

2.20e-04194684c95d5c4ad0210ebd672926558cc8331e6396a854
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MORN1 TTC21A DYNLT5 DNAH11

2.20e-041946844a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCellCOVID-19-Heart-CM_1|Heart / Disease (COVID-19 only), tissue and cell type

SPHKAP SVIL SLC4A4 TENM2

2.24e-04195684f1ef50331eda8f1239dba6ea970df4eaccf032f1
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

SPHKAP SVIL UGT2B7 TENM2

2.24e-0419568475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

TBX3 MAN1A1 ADAMTS18 DOC2B

2.24e-041956842fa0216ba493d9722324c0a9a0c59c40e72b3c4e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Stem_cells-retina_progenitors|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

TBX3 MAN1A1 ADAMTS18 DOC2B

2.24e-0419568406a437459717dc3c41ec343b1ec57cf910ecbdd8
ToppCellmoderate-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMEM232 TTC21A DYNLT5 DNAH11

2.24e-041956843486eae5fdb062a75a907b896c9d7b396d2aa195
ToppCellmoderate-Epithelial-Ciliated|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMEM232 TTC21A DYNLT5 DNAH11

2.24e-04195684e80f5cdf0b18066b3e6c2f5452e58f101c67932c
ToppCelltumor_Lung-Myeloid_cells-Alveolar_Mac|Myeloid_cells / Location, Cell class and cell subclass

STXBP2 SPI1 SVIL LRPAP1

2.24e-041956843133591a289c06396cf4705d6a861369e145ac54
ToppCellPCW_05-06-Mesenchymal|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

TBX3 TENM4 PTPRG SLC4A4

2.29e-04196684dca52c57ba35d9395cdbca8b881f12ece721b10f
ToppCellControl|World / Condition, Lineage and Cell class

STXBP2 SPI1 SVIL LRPAP1

2.29e-041966842565f567c5274d1689e11600a2cb9e6770b65f74
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMEM232 DYNC2LI1 DYNLT5 DNAH11

2.29e-0419668427b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCellPCW_07-8.5-Mesenchymal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

TBX3 TENM4 PTPRG SLC4A4

2.29e-041966848e10802f52e5e1853ea4ad34bf9a32a34e6112b5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAN1A1 SPI1 DOCK11 MERTK

2.29e-04196684cbc727b55b6433a701b1a331028a49960fcee6ee
ToppCellNS-control-d_0-4-Epithelial-Ciliated|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

TMEM232 TTC21A DYNLT5 DNAH11

2.29e-04196684d46ab80554dd3c1cc81e1938ea2acfd5e85c6d2a
ToppCell3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

OSBPL3 TTC21A DYNLT5 DNAH11

2.33e-0419768474a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCellnucseq-Immune-Immune_Myeloid-AM-AM|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPI1 DOCK11 SVIL LRPAP1

2.33e-04197684360f75ba6845128b045959e133e38ffd3d377ed9
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMEM232 TTC21A DYNLT5 DNAH11

2.33e-04197684e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Myeloid-Non-resident_Macrophage|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

JAK3 STXBP2 PSME4 KDM3B

2.33e-04197684df2fe36cb96e2565a9d21c24cb4e451e8befd4be
ToppCellnucseq-Immune-Immune_Myeloid-AM|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SPI1 DOCK11 SVIL LRPAP1

2.33e-04197684edb652af64d296b9031c9a690f0c70895a5eda2c
ToppCellTracheal-10x5prime-Epithelial-Epi_airway_ciliated-Deuterosomal|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TMEM232 TTC21A DYNLT5 DNAH11

2.33e-041976846e4a411ef823ce9e16f420e185e21fa19d13af34
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMEM232 TTC21A DYNLT5 DNAH11

2.33e-04197684d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

TMEM232 DYNC2LI1 DYNLT5 DNAH11

2.38e-04198684ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAN1A1 OSBPL3 MERTK BFSP2

2.38e-04198684567fcf882c8612356946240843525b786f3c8dbe
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STXBP2 SPI1 DOCK11 LRPAP1

2.38e-041986841774dd36315a04c4cdcef2cc674204e4ab9c175b
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

STXBP2 SPI1 DOCK11 LRPAP1

2.38e-04198684768df928a3265dbe7cce2acea07b2f6d6b709642
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MAN1A1 SMPDL3B OSBPL3 MERTK

2.42e-041996841bb02f41f3cc76a28581e38b0ca4c36b930b85b4
ToppCellControl-Myeloid-TRAM1|Control / Condition, Lineage and Cell class

STXBP2 SPI1 SVIL LRPAP1

2.42e-041996848785ea74b006df8d115885eaad429289c41e8d5b
Drug7,8-benzoquinoline

UGT2B4 UGT2B7 SLC4A4 UGT2B11

8.22e-0643684CID000009191
Drug2-hydroxyestriol

UGT2B7 UGT2B11

8.79e-062682ctd:C008012
DrugC1 11-32

UGT2B4 UGT2B7 UGT2B11

2.01e-0518683CID000443077
DrugC11131

UGT2B4 UGT2B7 UGT2B11

2.01e-0518683CID000443076
DrugT4-G

UGT2B4 UGT2B7 UGT2B11

2.39e-0519683CID000152424
Drug5 alpha-dihydroaldosterone

UGT2B4 UGT2B7

2.63e-053682CID003036614
DrugNSC76436

UGT2B4 UGT2B7 ACKR2

2.80e-0520683CID000002828
DrugMK-886; Up 200; 1uM; MCF7; HG-U133A

SMPDL3B RALGPS1 PCSK6 SVIL BFSP2 ZNF446

2.80e-05198686264_UP
DrugUDP-alpha-d-xylopyranose

TRIT1 UGT2B4 UGT2B7 UGT2B11

3.13e-0560684CID000001165
Drugestriol-16-glucuronide

UGT2B4 UGT2B7 UGT2B11

3.26e-0521683CID000122281
Drugestradiol-3-glucuronide

UGT2B4 UGT2B7 UGT2B11

4.32e-0523683CID000066651
DrugHymecromone

UGT2B4 UGT2B7 UGT2B11

5.59e-0525683ctd:D006923
DrugL-idaro-1,4-lactone

UGT2B4 UGT2B7 UGT2B11

7.91e-0528683CID000078997
Drughyodeoxycholic acid

UGT2B4 UGT2B7

8.74e-055682ctd:C010471
DrugAmobarbital

UGT2B4 UGT2B7

8.74e-055682ctd:D000654
Drugphenolphthalin

UGT2B4 UGT2B7

8.74e-055682CID000066494
DrugAC1N8H7N

UGT2B4 UGT2B7 ACKR2 UGT2B11

8.79e-0578684CID004318740
Drug7-hydroxycoumarin glucuronide

UGT2B4 UGT2B7 UGT2B11

8.81e-0529683CID000125641
Diseaseplasma clozapine-to-N-desmethylclozapine ratio measurement

UGT2B4 UGT2B7 UGT2B11

9.74e-079683EFO_0600040
DiseaseX-19141 measurement

UGT2B4 UGT2B7 UGT2B11

3.29e-0613683EFO_0800799
DiseaseWarsaw breakage syndrome (implicated_via_orthology)

DDX12P DDX11

1.57e-053682DOID:0060535 (implicated_via_orthology)
DiseaseX-24947 measurement

UGT2B4 UGT2B7 UGT2B11

1.75e-0522683EFO_0800910
DiseaseCluster headache

STXBP2 MERTK

5.21e-055682HP_0012199
Diseasevitamin D deficiency

UGT2B4 UGT2B7 UGT2B11

8.60e-0537683EFO_0003762
Diseasejuvenile myelomonocytic leukemia (is_implicated_in)

JAK3 PTPN11

1.09e-047682DOID:0050458 (is_implicated_in)
Diseasevitamin D measurement

UGT2B4 UGT2B7 ZNF808 SLC4A4 UGT2B11 DNAH11

1.26e-04336686EFO_0004631
Diseasefibromuscular dysplasia

LIMA1 STXBP2 SVIL

1.45e-0444683EFO_1000938
Diseasevitamin D measurement, COVID-19

UGT2B4 UGT2B7 SLC4A4

2.00e-0449683EFO_0004631, MONDO_0100096
Diseaseresponse to vaccine, cytokine measurement

MAN1A1 SLC4A4 TENM2 AGBL3

2.42e-04131684EFO_0004645, EFO_0004873
Diseasebipolar I disorder

TENM4 KDM3B BRINP1 ANKRD23

3.21e-04141684EFO_0009963
Diseasedisease progression measurement

UGT2B4 UGT2B7 UGT2B11

3.83e-0461683EFO_0008336
Diseaseunipolar depression, bipolar disorder

TENM4 OSBPL3 BRINP1 TENM2

4.71e-04156684EFO_0003761, MONDO_0004985
Diseaselate-onset Alzheimers disease

TENM4 SPI1 PCSK6 SENP7 CEP63

5.75e-04292685EFO_1001870
Diseasemyopia (is_implicated_in)

ZNF644 LRPAP1

6.15e-0416682DOID:11830 (is_implicated_in)
Diseaseuridine diphosphate galactose measurement, uridine diphosphate glucose measurement

SVIL ADAMTS18

6.96e-0417682EFO_0010543, EFO_0010544
Diseasebacteriemia

PTPRG UGT2B4

6.96e-0417682EFO_0003033
Diseasephosphatidylcholine 36:4 measurement

UGT2B4 UGT2B11

7.82e-0418682EFO_0010382
Diseaseserum alanine aminotransferase measurement

PTPN11 TENM4 ADAMTS18 ACKR2 MERTK SENP7 DDX11 DOC2B

8.51e-04869688EFO_0004735
Diseaseemphysema pattern measurement

SVIL SOWAHB

8.72e-0419682EFO_0005850
DiseaseNoonan-Like Syndrome With Loose Anagen Hair

PTPN11 RASA1

8.72e-0419682C3501846
DiseaseCostello syndrome (disorder)

PTPN11 RASA1

8.72e-0419682C0587248
DiseaseJuvenile Myelomonocytic Leukemia

JAK3 PTPN11

8.72e-0419682C0349639
DiseaseNoonan syndrome-like disorder with loose anagen hair

PTPN11 RASA1

8.72e-0419682C1843181
DiseaseCardio-facio-cutaneous syndrome

PTPN11 RASA1

8.72e-0419682C1275081
Diseasealcohol use disorder (implicated_via_orthology)

STXBP2 SPI1 RASA1 KDM3B

1.08e-03195684DOID:1574 (implicated_via_orthology)
DiseaseLEOPARD Syndrome

PTPN11 RASA1

1.17e-0322682C0175704
Diseaseneuritic plaque measurement

PTPRG UGT2B4 UGT2B7 ICE1 UGT2B11

1.27e-03349685EFO_0006798
DiseaseNoonan Syndrome

PTPN11 RASA1

1.40e-0324682C0028326
Diseaseglaucoma (biomarker_via_orthology)

PTPN11 SQSTM1

1.90e-0328682DOID:1686 (biomarker_via_orthology)
DiseaseMental deterioration

TENM4 DNAH11

2.04e-0329682HP_0001268
Diseasediverticular disease

GPR158 UGT2B4 UGT2B7 UGT2B11

2.18e-03236684EFO_0009959

Protein segments in the cluster

PeptideGeneStartEntry
GRFKAEKVEFHWGHS

PTPRG

141

P23470
HADFGGHGTIWKLFL

ACKR2

196

O00590
EKEAKAHHIGWQRIG

AGBL3

246

Q8NEM8
IWDILTGHKKRGFHC

EIF3B

406

P55884
DKLHRTALHWACLKG

ANKRD23

141

Q86SG2
KEFDWLISDRGPFHH

BRINP1

36

O60477
NHEFWRKEIHGRIKD

DYNLT5

26

Q8N7M0
FIHHATREWKDGKIV

DNAH11

2216

Q96DT5
GEELDKLWREFLHHK

LRPAP1

166

P30533
KKERQPLHWAAFLGH

ANKRD52

171

Q8NB46
LKRGLENTLHDAKHW

BFSP2

341

Q13515
WQSALIGKNGKRHDH

ADAMTS18

371

Q8TE60
REEDPHEGKIWFHGK

RASA1

341

P20936
GSRFHAILWHKHLDD

RALGPS1

526

Q5JS13
LEWHENLGHGSFTKI

JAK3

521

P52333
GEWKAGRKHGHGKLL

MORN1

41

Q5T089
GDREWAAHIKSKSHL

TRIT1

406

Q9H3H1
FGHRPHKDLWASKNE

LIMA1

456

Q9UHB6
WKDGKELLGAHHAIT

MERTK

131

Q12866
RRKDGLGGDKSHFKW

GPR158

251

Q5T848
ARAEPGKFWHIADLH

SMPDL3B

16

Q92485
KEGWKHRLFLSHREG

HPS5

61

Q9UPZ3
KHGGWLLREHQAGFE

DCLK3

271

Q9C098
RAKGHNTPKDIAHFW

DYNC2LI1

71

Q8TCX1
AHLKASDWKVNGAGH

PCSK6

456

P29122
QRIHDGKEKPGALWH

KDM3B

1601

Q7LBC6
RWFHGHLSGKEAEKL

PTPN11

111

Q06124
VHAHWEKGGLLGRLA

DDX11

716

Q96FC9
AINWAGGLHHAKKFE

HDAC3

126

O15379
WHHSDLLRKGGEESL

ICE1

791

Q9Y2F5
HDAWLSKHFGIDRKS

DOCK11

1336

Q5JSL3
VLGIHAKGERLKHWF

DOC2B

371

Q14184
KDLLDRGHFLSGWHT

FCN2

106

Q15485
VAHKKSEWEGRTHAL

CEP63

36

Q96MT8
HAHWEKGGLLGRLAA

DDX12P

736

Q92771
EWKGGLLEHKMGHLT

MAN1A1

461

P33908
HHGLSEGWKETEKFG

SBSN

211

Q6UWP8
DRSGKAVHRLFGKWH

OSBPL3

741

Q9H4L5
IRKAHPDKDWFHLVG

MIOX

106

Q9UGB7
HLKRFGLWKSKDDNH

SENP7

566

Q9BQF6
VHRKSWKVGDIFHAV

SPHKAP

1661

Q2M3C7
IHKHGDSVWELLKGT

TRIM45

231

Q9H8W5
HLEAKELWDQFHKRG

TBX3

106

O15119
LEKGHAKHWFSSLRP

SNAP47

116

Q5SQN1
HTHAAKDFWKLLGGQ

SVIL

1526

O95425
AHETGLPWAGLHKRK

SPPL2C

656

Q8IUH8
LGGWSLDKHHILNVK

TENM2

1176

Q9NT68
KGDKLLRHWASEIEH

RNF217

401

Q8TC41
FSSKHKEALAHRWGI

SPI1

201

P17947
GYTALHWIAKHGDLR

SOWAHB

631

A6NEL2
SEGFSHSRWLRKVKH

SQSTM1

176

Q13501
GDSWKELAHRAFFHG

ADPRH

286

P54922
KGAKHLRVAAHDLTW

UGT2B4

471

P06133
WKLNFQHLSGERGHK

TMEM232

26

C9JQI7
AVSARFGHWHKNKAG

STXBP2

511

Q15833
FGHWHKNKAGIEARA

STXBP2

516

Q15833
LVWHRRLHGGEKSYK

ZNF808

666

Q8N4W9
SKLGGWSLDKHHALN

TENM4

1166

Q6N022
KGAKHLRVAAHDLTW

UGT2B11

471

O75310
AGLFLWLIGRHDKAK

TTC21A

116

Q8NDW8
LHHKGFKLWFDELIG

PSME4

226

Q14997
AFDWKSQLVIHRKGH

ZNF446

431

Q9NWS9
HVRGHLKRLGKTKWD

ZNF644

1056

Q9H582
HKLKKGAGYHLDLFW

SLC4A4

811

Q9Y6R1
VFRGHKKEATAVAWH

WDR33

326

Q9C0J8
KGAKHLRVAAHDLTW

UGT2B7

471

P16662
TWKHLHADRIGRGSK

TERB1

446

Q8NA31
GKGFGDHIHWRTLED

TXNDC12

31

O95881
ESLHEWKECGRGFIH

ZNF266

181

Q14584