Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainPPASE_MYOTUBULARIN

MTMR1 SBF2

8.86e-0514192PS51339
DomainMyotubularin-like_Pase_dom

MTMR1 SBF2

8.86e-0514192IPR010569
DomainMyotubularin_fam

MTMR1 SBF2

8.86e-0514192IPR030564
DomainMyotub-related

MTMR1 SBF2

8.86e-0514192PF06602
DomainGRAM

MTMR1 SBF2

1.17e-0416192SM00568
DomainHomeobox_Antennapedia_CS

HOXC5 HOXC8

2.04e-0421192IPR001827
DomainGRAM

MTMR1 SBF2

2.24e-0422192PF02893
DomainGRAM

MTMR1 SBF2

2.24e-0422192IPR004182
DomainANTENNAPEDIA

HOXC5 HOXC8

2.67e-0424192PS00032
DomainHomeobox_metazoa

HOXC5 HOXC8

3.72e-0390192IPR020479
DomainProt-tyrosine_phosphatase-like

MTMR1 SBF2

4.48e-0399192IPR029021
DomainHomeobox_CS

HOXC5 HOXC8

1.51e-02186192IPR017970
DomainHomeobox

HOXC5 HOXC8

2.32e-02234192PF00046
DomainHOMEOBOX_1

HOXC5 HOXC8

2.36e-02236192PS00027
DomainHOX

HOXC5 HOXC8

2.38e-02237192SM00389
DomainHomeobox_dom

HOXC5 HOXC8

2.42e-02239192IPR001356
DomainHOMEOBOX_2

HOXC5 HOXC8

2.42e-02239192PS50071
Pubmed

Isolation and regional localization of the murine homeobox-containing gene Hox-3.3 to mouse chromosome region 15E.

HOXC5 HOXC8

1.70e-0641922570032
Pubmed

Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes.

HOXC5 HOXC8

4.24e-0661927585967
Pubmed

Mammalian-specific ectodermal enhancers control the expression of Hoxc genes in developing nails and hair follicles.

HOXC5 HOXC8

4.24e-06619233199643
Pubmed

Sequence and embryonic expression of the murine Hox-3.5 gene.

HOXC5 HOXC8

5.93e-0671921363091
Pubmed

A combination of activation and repression by a colinear Hox code controls forelimb-restricted expression of Tbx5 and reveals Hox protein specificity.

HOXC5 HOXC8

5.93e-06719224651482
Pubmed

Mouse Hox-3.4: homeobox sequence and embryonic expression patterns compared with other members of the Hox gene network.

HOXC5 HOXC8

7.90e-0681921976088
Pubmed

Tgif1 and Tgif2 Regulate Axial Patterning in Mouse.

HOXC5 HOXC8

7.90e-06819227187787
Pubmed

Hoxc gene collinear expression and epigenetic modifications established during embryogenesis are maintained until after birth.

HOXC5 HOXC8

1.02e-05919224155669
Pubmed

Altered cellular proliferation and mesoderm patterning in Polycomb-M33-deficient mice.

HOXC5 HOXC8

1.02e-0591929043087
Pubmed

Identification of the murine Hox-c12 and Hox-c13 homeoboxes on yeast artificial chromosomes.

HOXC5 HOXC8

1.02e-0591927959778
Pubmed

Genomic analysis of mouse retinal development.

OSTC TMEM94 SCG2 CNOT4 PRRC2B TMEM59L

1.13e-05100619615226823
Pubmed

Characterization of the myotubularin dual specificity phosphatase gene family from yeast to human.

MTMR1 SBF2

1.27e-05101929736772
Pubmed

Cognate homeo-box loci mapped on homologous human and mouse chromosomes.

HOXC5 HOXC8

1.55e-05111922878432
Pubmed

Specification of vertebral identity is coupled to Notch signalling and the segmentation clock.

HOXC5 HOXC8

1.86e-051219214960495
Pubmed

A role for mel-18, a Polycomb group-related vertebrate gene, during theanteroposterior specification of the axial skeleton.

HOXC5 HOXC8

2.20e-05131928625838
Pubmed

The Polycomb-group homolog Bmi-1 is a regulator of murine Hox gene expression.

HOXC5 HOXC8

2.20e-05131928887324
Pubmed

Placentation defects are highly prevalent in embryonic lethal mouse mutants.

PITRM1 CNOT4 PRRC2B

2.36e-0510319329539633
Pubmed

Organization and expression of mouse Hox3 cluster genes.

HOXC5 HOXC8

2.56e-05141928099712
Pubmed

Characterization of chromosomal inversion of the mouse hairy ears (Eh) mutation associated with cleft palate.

HOXC5 HOXC8

3.38e-051619217520166
Pubmed

Hox genes and the evolution of vertebrate axial morphology.

HOXC5 HOXC8

3.38e-05161927768176
Pubmed

Genetic and functional modularity of Hox activities in the specification of limb-innervating motor neurons.

HOXC5 HOXC8

4.30e-051819223359544
Pubmed

Hox Proteins Coordinate Motor Neuron Differentiation and Connectivity Programs through Ret/Gfrα Genes.

HOXC5 HOXC8

4.30e-051819226904955
Pubmed

The mouse PcG gene eed is required for Hox gene repression and extraembryonic development.

HOXC5 HOXC8

5.34e-052019212370779
Pubmed

Sustained Hox5 gene activity is required for respiratory motor neuron development.

HOXC5 HOXC8

5.34e-052019223103965
Pubmed

Organization of human class I homeobox genes.

HOXC5 HOXC8

6.49e-05221922576652
Pubmed

Targeted disruption of the mouse homologue of the Drosophila polyhomeotic gene leads to altered anteroposterior patterning and neural crest defects.

HOXC5 HOXC8

7.75e-05241929367423
Pubmed

Fine mapping of human HOX gene clusters.

HOXC5 HOXC8

9.12e-05261928646877
Pubmed

The human HOX gene family.

HOXC5 HOXC8

1.14e-04291922574852
Pubmed

Sf3b4 regulates chromatin remodeler splicing and Hox expression.

HOXC5 HOXC8

1.39e-043219237167859
Pubmed

Global control of motor neuron topography mediated by the repressive actions of a single hox gene.

HOXC5 HOXC8

1.76e-043619220826310
Pubmed

Atlas of Hox gene expression in the developing kidney.

HOXC5 HOXC8

1.96e-043819215042701
Pubmed

Complete mutation analysis panel of the 39 human HOX genes.

HOXC5 HOXC8

1.96e-043819211857506
Pubmed

Lysine demethylase 7a regulates murine anterior-posterior development by modulating the transcription of Hox gene cluster.

HOXC5 HOXC8

2.07e-043919233257809
Pubmed

Quantification of Hox and surfactant protein-B transcription during murine lung development.

HOXC5 HOXC8

2.18e-044019219204410
Pubmed

Lin28a/let-7 pathway modulates the Hox code via Polycomb regulation during axial patterning in vertebrates.

HOXC5 HOXC8

2.29e-044119232479258
Pubmed

Reduction of Hox gene expression by histone H1 depletion.

HOXC5 HOXC8

2.52e-044319222701719
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

TMEM94 RPTOR SBF2 PRRC2B TPCN1

2.57e-04110519535748872
Pubmed

Nomenclature for human homeobox genes.

HOXC5 HOXC8

2.64e-04441921973146
Pubmed

Vertebrate homeobox gene nomenclature.

HOXC5 HOXC8

3.01e-04471921358459
Pubmed

Control of spinal motor neuron terminal differentiation through sustained Hoxc8 gene activity.

HOXC5 HOXC8

3.27e-044919235315772
Pubmed

New insights into the role of Jmjd3 and Utx in axial skeletal formation in mice.

HOXC5 HOXC8

3.41e-045019228188179
Cytoband12q13.3

HOXC5 HOXC8

2.04e-045119212q13.3
CytobandXq28

MTMR1 PLXNB3

2.39e-03176192Xq28
CytobandEnsembl 112 genes in cytogenetic band chrXq28

MTMR1 PLXNB3

3.48e-03213192chrXq28
CytobandEnsembl 112 genes in cytogenetic band chr17q25

TMEM94 RPTOR

7.07e-03307192chr17q25
CytobandEnsembl 112 genes in cytogenetic band chr12q13

HOXC5 HOXC8

1.31e-02423192chr12q13
GeneFamilyMyotubularins|Phosphoinositide phosphatases

MTMR1 SBF2

4.22e-0515122903
GeneFamilyHOXL subclass homeoboxes

HOXC5 HOXC8

5.26e-0452122518
ToppCellTCGA-Thymus-Primary_Tumor-Thymoma-Type_C|TCGA-Thymus / Sample_Type by Project: Shred V9

CREG2 HOXC5 HOXC8

4.33e-051631932dac87d15051151ccf193760ddd8b82534c3f922
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|356C / Donor, Lineage, Cell class and subclass (all cells)

PITRM1 IL18RAP MTMR1

4.41e-05164193d5bb57c321f2973836efc8990449494cc1fb87c7
ToppCellfacs-Trachea-3m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SCG2 HOXC5 TMEM59L

4.91e-05170193941d637cf76918ee4b0a1833abd1a42593cb8b1a
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCG2 HOXC5 TMEM59L

5.26e-05174193ecdff386d7f0bc57c170a2c1f4deae5ba7e431b5
ToppCell10x3'2.3-week_17-19-Neuro-stroma-schwann_cells|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PLXNB3 HOXC5 HOXC8

5.35e-051751938b010220cdfb680ec839572f4933adfb85045ea6
ToppCell10x3'2.3-week_17-19-Neuro-stroma|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PLXNB3 HOXC5 HOXC8

5.35e-051751930b579aeadcc06be83627391c0b01bd8605fdbdf3
ToppCell10x3'2.3-week_17-19-Neuro|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

PLXNB3 HOXC5 HOXC8

5.35e-05175193bbce8b1a160b414c0bf643c21c4e5e78fbccb7e1
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCG2 HOXC5 TMEM59L

5.63e-05178193d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-3|TCGA-Lung / Sample_Type by Project: Shred V9

MTMR1 ACP7 HOXC8

6.21e-05184193ea4ccebe2d54279fcc517e4f0bfa652b91a808bb
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSTC SCG2 TMEM59L

6.62e-0518819363773854bf8430fb8229edb385b953a89833d08c
ToppCellfacs-Pancreas-Endocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCG2 PRRC2B TMEM59L

6.73e-05189193010fdd70e9d0e21b856306a29ff877776a480319
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCG2 PRRC2B TMEM59L

6.94e-05191193a251b134f67a0a1ef3a42f50042f128a17f20b22
ToppCellfacs-Pancreas-Endocrine|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSTC SCG2 TMEM59L

7.16e-0519319315c86e20b97b6983410b36d308cddff56d141c98
ToppCellfacs-Pancreas-Endocrine-18m-Epithelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OSTC SCG2 TMEM59L

7.27e-0519419370a61b74f1c01abc6f8779b564faae508895a18e
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-midbrain/hindbrain_cells|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

SCG2 CREG2 TMEM59L

7.61e-05197193c7078f6fcf27319ba8c5ebe700bcae7f1e7e39c1
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-1_mon-Neuronal|1_mon / Sample Type, Dataset, Time_group, and Cell type.

SCG2 CREG2 TMEM59L

7.84e-05199193f94307958cead25d38103fcbb35fa45011de1687
DiseaseMoyamoya disease

RPTOR SBF2

3.02e-0440192MONDO_0016820
Diseasepathological myopia

RPTOR DMAC1

2.30e-03111192EFO_0004207
Diseasecannabis dependence

CNOT4 DMAC1

3.38e-03135192EFO_0007191

Protein segments in the cluster

PeptideGeneStartEntry
QHKGFMMEPDWPLYP

TMEM59L

306

Q9UK28
YWVARKPMKMGYPPS

DMAC1

66

Q96GE9
KQAMFSRHPGMRKWP

CREG2

236

Q8IUH2
YVRWNPRMRPQMPIH

MTMR1

601

Q13613
KPPWLHMPSAMTVYA

OSTC

21

Q9NRP0
AARPWIITMGHRPMY

ACP7

276

Q6ZNF0
APPQIYPWMTKLHMS

HOXC5

136

Q00444
PPNSRFWAKMRYHMP

IL18RAP

546

O95256
GPSYDWMMLTPKHFP

SBF2

1591

Q86WG5
LHHFMAPVMARWPPF

PLXNB3

11

Q9ULL4
SLMFPWMRPHAPGRR

HOXC8

136

P31273
IPMHFWALFYPKRAM

PIWIL2

601

Q8TC59
WQMKTHFLMPFPVNY

PITRM1

851

Q5JRX3
WPERKLKHMQFPPMY

SCG2

156

P13521
SSPRLPPTYMHAMWQ

RPTOR

366

Q8N122
ARYPWMAFPRNSIMH

CNOT4

496

O95628
QWPSAMYPDLHMPFA

TMEM94

146

Q12767
MYPDLHMPFAPSWSL

TMEM94

151

Q12767
YPHHPQMLGFDPRWM

PRRC2B

661

Q5JSZ5
NFPDVMMPSYSRNPW

TPCN1

281

Q9ULQ1