Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiontransporter activity

SLC37A1 ATP6V0A1 PSG2 PSG11 OTOP2 SLC5A7 ATP10B PANX1 ATP9B ASIC5 ABCC6 CFHR4 GJE1 SLC16A6 SLC25A40 SLCO2A1 CIDEC ATP6V0A4 SCN4A SLC25A10 SLC6A20 SCNN1A SLC9A7 SLC45A1 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.56e-08128913128GO:0005215
GeneOntologyMolecularFunctiontransmembrane transporter activity

SLC37A1 ATP6V0A1 PSG2 PSG11 OTOP2 SLC5A7 PANX1 ASIC5 ABCC6 GJE1 SLC16A6 SLC25A40 SLCO2A1 ATP6V0A4 SCN4A SLC25A10 SLC6A20 SCNN1A SLC9A7 SLC45A1 ATP1A1 ATP1A3 ATP4A ATP6V0A2

6.55e-07118013124GO:0022857
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC5A7 ASIC5 SCN4A SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A

1.94e-061711319GO:0015081
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

SLC37A1 ATP6V0A1 OTOP2 SLC5A7 PANX1 ASIC5 ABCC6 ATP6V0A4 SCN4A SLC25A10 SLC6A20 SCNN1A SLC9A7 SLC45A1 ATP1A1 ATP1A3 ATP4A ATP6V0A2

2.33e-0675813118GO:0015318
GeneOntologyMolecularFunctionATP-dependent activity

ATP6V0A1 DNAH2 ATP10B ATP9B ABCC6 DNAH1 STARD9 ATP6V0A4 UBA6 CHD6 ATP1A1 ASCC3 ATP1A3 POLQ ATP4A ATP6V0A2

2.75e-0661413116GO:0140657
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC37A1 ATP6V0A1 SLC5A7 ABCC6 SLCO2A1 ATP6V0A4 SLC25A10 SLC6A20 SLC9A7 SLC45A1 ATP1A1 ATP1A3 ATP4A ATP6V0A2

3.11e-0647713114GO:0022804
GeneOntologyMolecularFunctionATPase-coupled monoatomic cation transmembrane transporter activity

ATP6V0A1 ATP6V0A4 ATP1A1 ATP1A3 ATP4A ATP6V0A2

3.23e-06621316GO:0019829
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ATP6V0A1 ABCC6 ATP6V0A4 ATP1A1 ATP1A3 ATP4A ATP6V0A2

7.61e-061091317GO:0042626
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

ATP6V0A1 OTOP2 SLC5A7 PANX1 ASIC5 ATP6V0A4 SCN4A SLC6A20 SCNN1A SLC9A7 SLC45A1 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.59e-0562713115GO:0022890
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

ATP6V0A1 SLC5A7 ATP6V0A4 SLC6A20 SLC9A7 SLC45A1 ATP1A1 ATP1A3 ATP4A ATP6V0A2

3.02e-0530113110GO:0022853
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

ATP6V0A1 OTOP2 SLC5A7 PANX1 ASIC5 ATP6V0A4 SCN4A SLC6A20 SCNN1A SLC9A7 SLC45A1 ATP1A1 ATP1A3 ATP4A ATP6V0A2

3.09e-0566413115GO:0008324
GeneOntologyMolecularFunctionP-type sodium transporter activity

ATP1A1 ATP1A3 ATP4A

3.20e-05101313GO:0008554
GeneOntologyMolecularFunctionP-type sodium:potassium-exchanging transporter activity

ATP1A1 ATP1A3 ATP4A

3.20e-05101313GO:0005391
GeneOntologyMolecularFunctionproton transmembrane transporter activity

ATP6V0A1 OTOP2 ASIC5 ATP6V0A4 SLC9A7 SLC45A1 ATP4A ATP6V0A2

3.43e-051881318GO:0015078
GeneOntologyMolecularFunctionP-type potassium transmembrane transporter activity

ATP1A1 ATP1A3 ATP4A

4.38e-05111313GO:0008556
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP6V0A4 ATP1A1 ATP1A3 ATP4A

8.86e-05361314GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP6V0A4 ATP1A1 ATP1A3 ATP4A

8.86e-05361314GO:0015662
GeneOntologyMolecularFunctionpotassium ion binding

HDAC4 ATP1A1 ATP4A

9.53e-05141313GO:0030955
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC37A1 PSG2 PSG11 PANX1 SLC16A6 SLC25A40 SLCO2A1 SLC25A10 SLC6A20

1.38e-042931319GO:0008514
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ATP6V0A1 ABCC6 ATP6V0A4 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.75e-041781317GO:0015399
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

ATP6V0A1 OTOP2 SLC5A7 PANX1 ASIC5 ATP6V0A4 SCN4A SLC6A20 SCNN1A SLC9A7 SLC45A1 ATP1A1 ATP1A3 ATP4A ATP6V0A2

2.23e-0479313115GO:0015075
GeneOntologyMolecularFunctionlipid transporter activity

PSG2 PSG11 ATP10B ATP9B CFHR4 SLCO2A1 CIDEC

3.16e-041961317GO:0005319
GeneOntologyMolecularFunctionpyridoxal phosphate binding

SHMT2 GOT1L1 GADL1 TAT

4.99e-04561314GO:0030170
GeneOntologyMolecularFunctionATPase-coupled ion transmembrane transporter activity

ATP6V0A1 ATP6V0A4 ATP6V0A2

5.05e-04241313GO:0042625
GeneOntologyMolecularFunctionATPase activity, coupled to transmembrane movement of ions, rotational mechanism

ATP6V0A1 ATP6V0A4 ATP6V0A2

5.05e-04241313GO:0044769
GeneOntologyMolecularFunctionproton-transporting ATPase activity, rotational mechanism

ATP6V0A1 ATP6V0A4 ATP6V0A2

5.05e-04241313GO:0046961
GeneOntologyMolecularFunctionvitamin B6 binding

SHMT2 GOT1L1 GADL1 TAT

5.34e-04571314GO:0070279
GeneOntologyMolecularFunctionalkali metal ion binding

HDAC4 ATP1A1 ATP4A

6.42e-04261313GO:0031420
GeneOntologyMolecularFunctionATP hydrolysis activity

DNAH2 ATP10B ATP9B ABCC6 CHD6 ATP1A1 ASCC3 ATP1A3 POLQ ATP4A

6.68e-0444113110GO:0016887
GeneOntologyMolecularFunctionsulfur compound transmembrane transporter activity

ABCC6 SLC16A6 SLC25A40 SLC25A10

6.91e-04611314GO:1901682
GeneOntologyMolecularFunctionsteroid hormone binding

ATP1A1 ATP1A3

8.78e-0471312GO:1990239
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

SLC5A7 PANX1 ASIC5 SCN4A SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A

9.99e-0446513110GO:0046873
GeneOntologyMolecularFunctionP-type proton-exporting transporter activity

ATP6V0A4 ATP4A

1.86e-03101312GO:0008553
GeneOntologyBiologicalProcessproton transmembrane transport

ATP6V0A1 OTOP2 ASIC5 ATP6V0A4 SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.42e-061701319GO:1902600
GeneOntologyBiologicalProcessimmune effector process

RAG2 ABL1 ABR PSG2 ENPP1 PSG11 PANX1 TLR7 CFI BCR BTN3A2 SVEP1 CFHR4 KLRK1 BTN3A3 CD28 MUC4

3.17e-0585913117GO:0002252
GeneOntologyBiologicalProcessnegative regulation of leukocyte mediated immunity

ABR PSG2 PSG11 BCR SVEP1 MUC4

3.40e-05961316GO:0002704
GeneOntologyBiologicalProcessintracellular sodium ion homeostasis

SCNN1A ATP1A1 ATP1A3 ATP4A

3.75e-05301314GO:0006883
GeneOntologyBiologicalProcessestablishment or maintenance of transmembrane electrochemical gradient

ATP1A1 ATP1A3 ATP4A

3.98e-05111313GO:0010248
GeneOntologyBiologicalProcessregulation of blood vessel remodeling

ABR PSG2 PSG11 BCR

4.87e-05321314GO:0060312
GeneOntologyBiologicalProcesssodium ion transmembrane transport

ASIC5 SCN4A SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A

5.60e-052081318GO:0035725
GeneOntologyBiologicalProcesssodium ion transport

SLC5A7 ASIC5 SCN4A SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A

6.69e-052751319GO:0006814
GeneOntologyBiologicalProcessleukocyte mediated immunity

ABR PSG2 ENPP1 PSG11 CFI BCR BTN3A2 SVEP1 CFHR4 KLRK1 BTN3A3 CD28 MUC4

7.86e-0557613113GO:0002443
GeneOntologyBiologicalProcessnegative regulation of neutrophil degranulation

ABR BCR

1.20e-0431312GO:0043314
GeneOntologyBiologicalProcesslymphocyte mediated immunity

PSG2 ENPP1 PSG11 CFI BTN3A2 SVEP1 CFHR4 KLRK1 BTN3A3 CD28 MUC4

1.40e-0444913111GO:0002449
GeneOntologyBiologicalProcessintracellular potassium ion homeostasis

ATP1A1 ATP1A3 ATP4A

1.60e-04171313GO:0030007
GeneOntologyBiologicalProcesssodium ion export across plasma membrane

ATP1A1 ATP1A3 ATP4A

1.60e-04171313GO:0036376
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

ATP6V0A1 ABL1 ENPP1 TMTC2 GRM5 TF ABCC6 ATP6V0A4 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.60e-0470513114GO:0055080
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

ATP6V0A1 ABL1 ENPP1 TMTC2 GRM5 TF ABCC6 ATP6V0A4 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.90e-0471713114GO:0050801
GeneOntologyBiologicalProcessnegative regulation of tissue remodeling

ABR PSG2 PSG11 BCR

2.24e-04471314GO:0034104
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

SLC37A1 ATP6V0A1 ABL1 OTOP2 PANX1 ASIC5 MS4A1 ATP6V0A4 SCN4A SLC25A10 SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

2.46e-04101713117GO:0098660
GeneOntologyBiologicalProcessregulation of immune response to tumor cell

PSG2 PSG11 KLRK1 MUC4

2.64e-04491314GO:0002837
GeneOntologyBiologicalProcessregulation of response to tumor cell

PSG2 PSG11 KLRK1 MUC4

2.85e-04501314GO:0002834
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

MS4A1 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A

2.96e-041421316GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

MS4A1 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A

2.96e-041421316GO:0098659
GeneOntologyBiologicalProcessnegative regulation of response to tumor cell

PSG2 PSG11 MUC4

3.06e-04211313GO:0002835
GeneOntologyBiologicalProcessnegative regulation of immune response to tumor cell

PSG2 PSG11 MUC4

3.06e-04211313GO:0002838
GeneOntologyBiologicalProcesssodium ion homeostasis

SCNN1A ATP1A1 ATP1A3 ATP4A

3.08e-04511314GO:0055078
GeneOntologyBiologicalProcessregulation of immune effector process

ABR PSG2 PSG11 PANX1 TLR7 BCR SVEP1 CFHR4 KLRK1 CD28 MUC4

3.36e-0449713111GO:0002697
GeneOntologyBiologicalProcessmonoatomic cation transport

ATP6V0A1 ABL1 MCHR1 OTOP2 SLC5A7 PANX1 ASIC5 TF MS4A1 ATP6V0A4 SCN4A SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

3.82e-04115713118GO:0006812
GeneOntologyBiologicalProcessresponse to glycoside

ATP1A1 ATP1A3

3.95e-0451312GO:1903416
GeneOntologyBiologicalProcessinorganic diphosphate transport

ENPP1 ABCC6

3.95e-0451312GO:0030505
GeneOntologyBiologicalProcessregulation of natural killer cell mediated cytotoxicity directed against tumor cell target

PSG2 PSG11 KLRK1

4.04e-04231313GO:0002858
GeneOntologyBiologicalProcessmonoatomic ion transport

ATP6V0A1 ABL1 MCHR1 OTOP2 SLC5A7 PANX1 ASIC5 TF ABCC6 MS4A1 ATP6V0A4 SCN4A SLC25A10 SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

4.18e-04137413120GO:0006811
GeneOntologyBiologicalProcessimmune response to tumor cell

PSG2 PSG11 KLRK1 MUC4

4.42e-04561314GO:0002418
GeneOntologyBiologicalProcessorganic anion transport

SLC37A1 PSG2 PSG11 PANX1 ABCC6 SLC16A6 SLC25A40 SLCO2A1 SLC25A10 SLC6A20 ATP1A3

4.53e-0451513111GO:0015711
GeneOntologyBiologicalProcessregulation of natural killer cell mediated immune response to tumor cell

PSG2 PSG11 KLRK1

4.60e-04241313GO:0002855
GeneOntologyBiologicalProcessnatural killer cell mediated cytotoxicity directed against tumor cell target

PSG2 PSG11 KLRK1

4.60e-04241313GO:0002420
GeneOntologyBiologicalProcessintracellular pH reduction

ATP6V0A1 ATP6V0A4 SLC9A7 ATP6V0A2

5.06e-04581314GO:0051452
GeneOntologyBiologicalProcesspositive regulation of type II interferon production

ABL1 TLR7 BTN3A2 BTN3A1 KLRK1

5.09e-041031315GO:0032729
GeneOntologyBiologicalProcessregulation of immune response

ABL1 ABR PSG2 PSG11 TLR7 CFI BCR BTN3A2 BTN3A1 SVEP1 CFHR4 KLRK1 BTN3A3 PTPRD MS4A1 CD28 MUC4

5.18e-04108513117GO:0050776
GeneOntologyBiologicalProcessnatural killer cell mediated immune response to tumor cell

PSG2 PSG11 KLRK1

5.20e-04251313GO:0002423
GeneOntologyBiologicalProcesscytokine production

FLT1 CHIA ABL1 PSG2 ENPP1 PSG11 PANX1 TLR7 NDRG2 BTN3A2 BTN3A1 KLRK1 BTN3A3 SULF2 BRCA1 CD28 EPHA2

5.51e-04109113117GO:0001816
GeneOntologyBiologicalProcesssnRNA transport

SNUPN NCBP2

5.91e-0461312GO:0051030
GeneOntologyBiologicalProcessB-1 B cell homeostasis

ABL1 ENPP1

5.91e-0461312GO:0001922
GeneOntologyBiologicalProcessnegative regulation of immune effector process

ABR PSG2 PSG11 BCR SVEP1 MUC4

6.77e-041661316GO:0002698
GeneOntologyBiologicalProcessimport across plasma membrane

MS4A1 SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A

6.78e-042301317GO:0098739
GeneOntologyBiologicalProcessregulation of cytokine production

FLT1 CHIA ABL1 PSG2 PSG11 PANX1 TLR7 NDRG2 BTN3A2 BTN3A1 KLRK1 BTN3A3 SULF2 BRCA1 CD28 EPHA2

6.78e-04101013116GO:0001817
GeneOntologyBiologicalProcesstype II interferon production

ABL1 ENPP1 TLR7 BTN3A2 BTN3A1 KLRK1

7.44e-041691316GO:0032609
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

ATP6V0A1 ABL1 OTOP2 PANX1 ASIC5 MS4A1 ATP6V0A4 SCN4A SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

7.68e-0492213115GO:0098662
GeneOntologyBiologicalProcesscirculatory system process

ABL1 ABR HDAC4 PSG2 PSG11 BCR SVEP1 SCN4A SLC6A20 SCNN1A SCPEP1 ATP1A1 ATP1A3

8.00e-0473313113GO:0003013
GeneOntologyBiologicalProcessregulation of leukocyte mediated immunity

ABR PSG2 PSG11 BCR SVEP1 KLRK1 CD28 MUC4

8.15e-043091318GO:0002703
GeneOntologyBiologicalProcessnegative regulation of blood vessel remodeling

ABR BCR

8.23e-0471312GO:0060313
GeneOntologyBiologicalProcessregulation of vascular endothelial growth factor production

FLT1 NDRG2 SULF2 BRCA1

8.26e-04661314GO:0010574
GeneOntologyBiologicalProcessblood circulation

ABL1 ABR HDAC4 PSG2 PSG11 BCR SVEP1 SCN4A SCNN1A SCPEP1 ATP1A1 ATP1A3

8.82e-0464813112GO:0008015
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

ATP6V0A1 ABL1 OTOP2 PANX1 ASIC5 MS4A1 ATP6V0A4 SCN4A SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

9.54e-0494213115GO:0098655
GeneOntologyCellularComponentcation-transporting ATPase complex

ATP6V0A1 ATP6V0A4 ATP1A1 ATP1A3 ATP4A ATP6V0A2

6.33e-07491326GO:0090533
GeneOntologyCellularComponentATPase dependent transmembrane transport complex

ATP6V0A1 ATP6V0A4 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.27e-06551326GO:0098533
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase, V0 domain

ATP6V0A1 ATP6V0A4 ATP6V0A2

2.86e-05101323GO:0000220
GeneOntologyCellularComponentproton-transporting V-type ATPase, V0 domain

ATP6V0A1 ATP6V0A4 ATP6V0A2

5.19e-05121323GO:0033179
GeneOntologyCellularComponentcell surface

PSG2 ENPP1 PSG11 TF BTN3A2 BTN3A1 ADGRG6 CFHR4 KLRK1 BTN3A3 SULF2 MS4A1 CD28 EPHA2 SCNN1A GPC5 ATP1A3 CDON

2.19e-04111113218GO:0009986
GeneOntologyCellularComponentphotoreceptor inner segment membrane

ATP1A1 ATP1A3

2.35e-0441322GO:0060342
GeneOntologyCellularComponentapical plasma membrane

PSG2 PSG11 SLC5A7 TF ABCC6 ATP6V0A4 SLC6A20 SCNN1A ATP1A1 MUC4 ATP4A

2.69e-0448713211GO:0016324
GeneOntologyCellularComponentdynein complex

DNAH2 DNAH1 CFAP70 DYNC1LI2

3.76e-04541324GO:0030286
GeneOntologyCellularComponentbasal plasma membrane

PSG2 ENPP1 PSG11 TF ABCC6 SLC16A6 SLCO2A1 ATP6V0A4 ATP1A1

4.23e-043541329GO:0009925
GeneOntologyCellularComponentaxonemal dynein complex

DNAH2 DNAH1 CFAP70

5.11e-04251323GO:0005858
GeneOntologyCellularComponentvacuolar proton-transporting V-type ATPase complex

ATP6V0A1 ATP6V0A4 ATP6V0A2

5.75e-04261323GO:0016471
GeneOntologyCellularComponentproton-transporting two-sector ATPase complex, proton-transporting domain

ATP6V0A1 ATP6V0A4 ATP6V0A2

5.75e-04261323GO:0033177
GeneOntologyCellularComponentbasal part of cell

PSG2 ENPP1 PSG11 TF ABCC6 SLC16A6 SLCO2A1 ATP6V0A4 ATP1A1

6.76e-043781329GO:0045178
GeneOntologyCellularComponentproton-transporting V-type ATPase complex

ATP6V0A1 ATP6V0A4 ATP6V0A2

7.97e-04291323GO:0033176
GeneOntologyCellularComponentbasolateral plasma membrane

PSG2 ENPP1 PSG11 ABCC6 SLC16A6 SLCO2A1 ATP6V0A4 ATP1A1

9.85e-043201328GO:0016323
GeneOntologyCellularComponentapical part of cell

PSG2 PSG11 SLC5A7 TF ABCC6 ATP6V0A4 SLC6A20 SCNN1A ATP1A1 MUC4 ATP4A

1.35e-0359213211GO:0045177
GeneOntologyCellularComponentexternal side of plasma membrane

PSG2 PSG11 BTN3A2 BTN3A1 CFHR4 KLRK1 BTN3A3 MS4A1 CD28 SCNN1A

1.71e-0351913210GO:0009897
GeneOntologyCellularComponentinner dynein arm

DNAH2 DNAH1

1.72e-03101322GO:0036156
GeneOntologyCellularComponentsodium:potassium-exchanging ATPase complex

ATP1A1 ATP1A3

2.51e-03121322GO:0005890
GeneOntologyCellularComponentlateral plasma membrane

PSG2 PSG11 ABCC6 ATP1A1

2.55e-03901324GO:0016328
GeneOntologyCellularComponentlysosomal membrane

VPS11 ATP6V0A1 ENPP1 RDH14 ATP10B TLR7 PGAP6 ATP6V0A4 ATP6V0A2

2.69e-034621329GO:0005765
GeneOntologyCellularComponentlytic vacuole membrane

VPS11 ATP6V0A1 ENPP1 RDH14 ATP10B TLR7 PGAP6 ATP6V0A4 ATP6V0A2

2.69e-034621329GO:0098852
GeneOntologyCellularComponentciliary membrane

MCHR1 PSG2 PSG11 SCNN1A

3.47e-03981324GO:0060170
HumanPhenoStippled calcification of the shoulder

ENPP1 ABCC6

9.83e-052512HP:0003836
HumanPhenoMyocardial calcification

ENPP1 ABCC6

9.83e-052512HP:0006690
HumanPhenoReduced leukocyte alkaline phosphatase

ABL1 BCR

9.83e-052512HP:0004852
HumanPhenoPh-positive acute lymphoblastic leukemia

ABL1 BCR

9.83e-052512HP:0004848
HumanPhenoMedial calcification of medium-sized arteries

ENPP1 ABCC6

9.83e-052512HP:0012457
HumanPhenoCortical nephrocalcinosis

ENPP1 ABCC6

9.83e-052512HP:0012409
HumanPhenoStippled calcification of the elbow

ENPP1 ABCC6

9.83e-052512HP:0003941
DomainV_ATPase_I

ATP6V0A1 ATP6V0A4 ATP6V0A2

1.31e-0641303PF01496
DomainV-type_ATPase_116kDa_su_euka

ATP6V0A1 ATP6V0A4 ATP6V0A2

1.31e-0641303IPR026028
DomainV-ATPase_116kDa_su

ATP6V0A1 ATP6V0A4 ATP6V0A2

1.31e-0641303IPR002490
Domain-

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

2.62e-063213053.40.1110.10
Domain-

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

2.62e-063213052.70.150.10
DomainATPase_P-typ_cyto_domN

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

4.15e-06351305IPR023299
DomainATPase_P-typ_P_site

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

4.79e-06361305IPR018303
DomainP_typ_ATPase

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

4.79e-06361305IPR001757
DomainATPASE_E1_E2

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

4.79e-06361305PS00154
DomainATPase_P-typ_transduc_dom_A

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

5.51e-06371305IPR008250
DomainE1-E2_ATPase

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

5.51e-06371305PF00122
DomainP-type_ATPase_IIC

ATP1A1 ATP1A3 ATP4A

6.49e-0661303IPR005775
DomainHAD-like_dom

ATP10B ATP9B LPIN2 ATP1A1 ATP1A3 ATP4A

1.86e-05791306IPR023214
Domain-

SHMT2 GOT1L1 GADL1 TAT

9.93e-053513043.90.1150.10
DomainPyrdxlP-dep_Trfase_major_sub2

SHMT2 GOT1L1 GADL1 TAT

1.11e-04361304IPR015422
DomainATPase_P-typ_TM_dom

ATP1A1 ATP1A3 ATP4A

1.73e-04161303IPR023298
Domain-

ATP1A1 ATP1A3 ATP4A

1.73e-041613031.20.1110.10
DomainIGv

FLT1 BTN3A2 BTN3A1 BTN3A3 CD28

1.77e-04751305SM00406
DomainPyrdxlP-dep_Trfase

SHMT2 GOT1L1 GADL1 TAT

1.86e-04411304IPR015424
DomainPyrdxlP-dep_Trfase_major_sub1

SHMT2 GOT1L1 GADL1 TAT

1.86e-04411304IPR015421
DomainATPase_P-typ_cation-transptr_C

ATP1A1 ATP1A3 ATP4A

2.09e-04171303IPR006068
DomainCation_ATPase_C

ATP1A1 ATP1A3 ATP4A

2.09e-04171303PF00689
DomainCation_ATPase_N

ATP1A1 ATP1A3 ATP4A

2.49e-04181303PF00690
DomainCation_ATPase_N

ATP1A1 ATP1A3 ATP4A

2.49e-04181303SM00831
DomainATPase_P-typ_cation-transptr_N

ATP1A1 ATP1A3 ATP4A

2.94e-04191303IPR004014
DomainSushi

CSMD2 CSMD3 SVEP1 CFHR4

4.68e-04521304PF00084
DomainIg_V-set

FLT1 PSG2 PSG11 BTN3A2 BTN3A1 BTN3A3 CD28

4.91e-041991307IPR013106
DomainCUB

ADGRB3 CSMD2 CSMD3 ADGRG6

5.04e-04531304PS01180
DomainCCP

CSMD2 CSMD3 SVEP1 CFHR4

5.41e-04541304SM00032
DomainSUSHI

CSMD2 CSMD3 SVEP1 CFHR4

6.22e-04561304PS50923
DomainSushi_SCR_CCP_dom

CSMD2 CSMD3 SVEP1 CFHR4

6.65e-04571304IPR000436
DomainCUB_dom

ADGRB3 CSMD2 CSMD3 ADGRG6

6.65e-04571304IPR000859
DomainAA_TRANSFER_CLASS_1

GOT1L1 TAT

7.08e-0461302PS00105
DomainASC

ASIC5 SCNN1A

1.68e-0391302PF00858
DomainASC

ASIC5 SCNN1A

1.68e-0391302PS01206
DomainNa+channel_ASC

ASIC5 SCNN1A

1.68e-0391302IPR001873
DomainV-set

PSG2 PSG11 BTN3A2 BTN3A1 BTN3A3 CD28

1.83e-031841306PF07686
DomainPTX

SVEP1 ADGRG6

2.09e-03101302SM00159
DomainGDS_CDC24_CS

ABR BCR PREX1

2.51e-03391303IPR001331
Domain-

SHMT2 GADL1 TAT

2.51e-033913033.40.640.10
DomainPentaxin-related

SVEP1 ADGRG6

2.54e-03111302IPR001759
DomainPentaxin

SVEP1 ADGRG6

2.54e-03111302PF00354
DomainDynein_heavy_chain_D4_dom

DNAH2 DNAH1

4.14e-03141302IPR024317
DomainDynein_HC_stalk

DNAH2 DNAH1

4.14e-03141302IPR024743
DomainDynein_heavy_dom-2

DNAH2 DNAH1

4.14e-03141302IPR013602
DomainDHC_N2

DNAH2 DNAH1

4.14e-03141302PF08393
DomainP_typ_ATPase_c

ATP10B ATP9B

4.14e-03141302IPR032630
DomainP-type_ATPase_N

ATP10B ATP9B

4.14e-03141302IPR032631
DomainATPase_dyneun-rel_AAA

DNAH2 DNAH1

4.14e-03141302IPR011704
DomainP-type_ATPase_IV

ATP10B ATP9B

4.14e-03141302IPR006539
DomainMT

DNAH2 DNAH1

4.14e-03141302PF12777
DomainAAA_8

DNAH2 DNAH1

4.14e-03141302PF12780
DomainPhoLip_ATPase_C

ATP10B ATP9B

4.14e-03141302PF16212
DomainPhoLip_ATPase_N

ATP10B ATP9B

4.14e-03141302PF16209
DomainAAA_5

DNAH2 DNAH1

4.14e-03141302PF07728
DomainDHC_fam

DNAH2 DNAH1

4.76e-03151302IPR026983
DomainDynein_heavy

DNAH2 DNAH1

4.76e-03151302PF03028
DomainDynein_heavy_dom

DNAH2 DNAH1

4.76e-03151302IPR004273
DomainCUB

CSMD2 CSMD3 ADGRG6

4.81e-03491303PF00431
DomainCUB

CSMD2 CSMD3 ADGRG6

5.09e-03501303SM00042
Domain-

CSMD2 CSMD3 ADGRG6

5.68e-035213032.60.120.290
DomainAminotran_1_2

GOT1L1 TAT

6.11e-03171302PF00155
DomainAminotransferase_I/II

GOT1L1 TAT

6.11e-03171302IPR004839
Domain-

FLT1 PSG2 PSG11 BTN3A2 BTN3A1 BTN3A3 FNDC7 PTPRD CD28 EPHA2 CDON

6.64e-03663130112.60.40.10
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP6V0A1 ATP10B ATP9B ASIC5 ATP6V0A4 SCNN1A ATP1A1 ATP1A3 ATP4A ATP6V0A2

2.12e-071769210MM15718
PathwayREACTOME_ION_CHANNEL_TRANSPORT

ATP6V0A1 ATP10B ATP9B ASIC5 ATP6V0A4 SCNN1A ATP1A1 ATP1A3 ATP4A ATP6V0A2

3.05e-071839210M997
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V0A1 SLC5A7 ATP10B ATP9B ASIC5 TF ABCC6 SLCO2A1 CIDEC ATP6V0A4 SLC25A10 SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.04e-067369218M27287
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

ATP6V0A1 SLC5A7 ATP10B ATP9B ASIC5 TF ABCC6 SLCO2A1 ATP6V0A4 SLC25A10 SLC6A20 SCNN1A SLC9A7 ATP1A1 ATP1A3 ATP4A ATP6V0A2

1.64e-066819217MM14985
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

2.85e-0555925M971
PathwayREACTOME_ION_TRANSPORT_BY_P_TYPE_ATPASES

ATP10B ATP9B ATP1A1 ATP1A3 ATP4A

3.40e-0557925MM15643
PathwayREACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING

ATP6V0A1 TF ATP6V0A4 ATP6V0A2

4.67e-0531924MM15639
PathwayREACTOME_TRANSFERRIN_ENDOCYTOSIS_AND_RECYCLING

ATP6V0A1 TF ATP6V0A4 ATP6V0A2

4.67e-0531924M991
PathwayREACTOME_BUTYROPHILIN_BTN_FAMILY_INTERACTIONS

BTN3A2 BTN3A1 BTN3A3

5.67e-0512923M27738
PathwayBIOCARTA_LIS1_PATHWAY

ABL1 DNAH2 DNAH1

2.42e-0419923M22005
PathwayWP_IMATINIB_AND_CHRONIC_MYELOID_LEUKEMIA

FLT1 ABL1 BCR

2.83e-0420923M39381
PathwayKEGG_PROXIMAL_TUBULE_BICARBONATE_RECLAMATION

SLC25A10 ATP1A1 ATP1A3

4.33e-0423923M4361
PathwayREACTOME_IRON_UPTAKE_AND_TRANSPORT

ATP6V0A1 TF ATP6V0A4 ATP6V0A2

4.81e-0456924MM15638
PathwayREACTOME_IRON_UPTAKE_AND_TRANSPORT

ATP6V0A1 TF ATP6V0A4 ATP6V0A2

5.51e-0458924M962
Pubmed

Common variation in GPC5 is associated with acquired nephrotic syndrome.

SULF2 GPC5 PREX1

5.34e-083132321441931
Pubmed

Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset.

BTN3A2 BTN3A1 BTN3A3

5.34e-083132322767497
Pubmed

Bcr/Abl interferes with the Fanconi anemia/BRCA pathway: implications in the chromosomal instability of chronic myeloid leukemia cells.

ABL1 BCR BRCA1

2.13e-074132321203397
Pubmed

Primate-specific BTN3A2 protects against SARS-CoV-2 infection by interacting with and reducing ACE2.

BTN3A2 BTN3A1 BTN3A3

2.13e-074132339142074
Pubmed

Differential localization of vacuolar H+-ATPases containing a1, a2, a3, or a4 (ATP6V0A1-4) subunit isoforms along the nephron.

ATP6V0A1 ATP6V0A4 ATP6V0A2

2.13e-074132317595521
Pubmed

Heteromeric interactions regulate butyrophilin (BTN) and BTN-like molecules governing γδ T cell biology.

BTN3A2 BTN3A1 BTN3A3

5.31e-075132329339503
Pubmed

The a subunit isoforms of vacuolar-type proton ATPase exhibit differential distribution in mouse perigastrulation embryos.

ATP6V0A1 ATP6V0A4 ATP6V0A2

5.31e-075132335948619
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A1 ATP1A3 ATP4A

1.06e-06613233036582
Pubmed

Aldolase directly interacts with ARNO and modulates cell morphology and acidic vesicle distribution.

ATP6V0A1 ATP6V0A4 ATP6V0A2

1.06e-066132321307348
Pubmed

Optic nerve compression and retinal degeneration in Tcirg1 mutant mice lacking the vacuolar-type H-ATPase a3 subunit.

ATP6V0A1 ATP6V0A4 ATP6V0A2

1.85e-067132320711468
Pubmed

The cluster of BTN genes in the extended major histocompatibility complex.

BTN3A2 BTN3A1 BTN3A3

1.85e-067132311170752
Pubmed

Receptor-mediated endocytosis: the intracellular journey of transferrin and its receptor.

ATP6V0A1 TF ATP6V0A4 ATP6V0A2

2.36e-062513242874839
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

SMG1 DNAH2 URB2 CSMD2 HORMAD1 ABCC6 CEP72 FDFT1 ARID2 CHD6 IL17RD PREX1

6.19e-066381321231182584
Pubmed

Integral and associated lysosomal membrane proteins.

VPS11 ENPP1 RDH14 PGAP6 ATP6V0A4 ATP6V0A2

9.04e-06126132617897319
Pubmed

Validation of a novel NGS based BCR::ABL1 kinase domain mutation detection assay in Indian cohort.

ABL1 BCR

1.43e-052132238977756
Pubmed

CircBA9.3 supports the survival of leukaemic cells by up-regulating c-ABL1 or BCR-ABL1 protein levels.

ABL1 BCR

1.43e-052132230224298
Pubmed

BCR-ABL1 kinase domain mutations may persist at very low levels for many years and lead to subsequent TKI resistance.

ABL1 BCR

1.43e-052132223799845
Pubmed

Curcumin derivative C817 inhibits proliferation of imatinib-resistant chronic myeloid leukemia cells with wild-type or mutant Bcr-Abl in vitro.

ABL1 BCR

1.43e-052132224487968
Pubmed

Ectopic Calcification and Hypophosphatemic Rickets: Natural History of ENPP1 and ABCC6 Deficiencies.

ENPP1 ABCC6

1.43e-052132234355424
Pubmed

Vestibular dysgenesis in mice lacking Abr and Bcr Cdc42/RacGAPs.

ABR BCR

1.43e-052132211921339
Pubmed

Deep sequencing reveals the spectrum of BCR-ABL1 mutations upon front-line therapy resistance in chronic myeloid leukemia: An Eastern-Indian cohort study.

ABL1 BCR

1.43e-052132236155130
Pubmed

Src family kinases phosphorylate the Bcr-Abl SH3-SH2 region and modulate Bcr-Abl transforming activity.

ABL1 BCR

1.43e-052132216912036
Pubmed

Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival.

ABL1 BCR

1.43e-052132222184410
Pubmed

The gatekeeper mutation T315I confers resistance against small molecules by increasing or restoring the ABL-kinase activity accompanied by aberrant transphosphorylation of endogenous BCR, even in loss-of-function mutants of BCR/ABL.

ABL1 BCR

1.43e-052132219369965
Pubmed

Emergence of a BCR::ABL1 rearrangement following a uniquely complex clonal evolution pattern in a patient undergoing Fms-like tyrosine kinase 3 inhibitor therapy for acute myeloid leukemia.

ABL1 BCR

1.43e-052132236180046
Pubmed

BCR-ABL1 compound mutations combining key kinase domain positions confer clinical resistance to ponatinib in Ph chromosome-positive leukemia.

ABL1 BCR

1.43e-052132225132497
Pubmed

Expression of P190 and P210 BCR/ABL1 in normal human CD34(+) cells induces similar gene expression profiles and results in a STAT5-dependent expansion of the erythroid lineage.

ABL1 BCR

1.43e-052132219135771
Pubmed

Expression of the p210BCR-ABL oncoprotein drives centrosomal hypertrophy and clonal evolution in human U937 cells.

ABL1 BCR

1.43e-052132217597804
Pubmed

Detection of bcr-abl gene expression at a low level in blood cells of some patients with essential thrombocythemia.

ABL1 BCR

1.43e-052132214966468
Pubmed

Expression profiling of adult acute lymphoblastic leukemia identifies a BCR-ABL1-like subgroup characterized by high non-response and relapse rates.

ABL1 BCR

1.43e-052132225769542
Pubmed

Analysis of the clinico-hematological relevance of the breakpoint location within M-BCR in chronic myeloid leukemia.

ABL1 BCR

1.43e-052132223269583
Pubmed

An accurate and rapid flow cytometric diagnosis of BCR-ABL positive acute lymphoblastic leukemia.

ABL1 BCR

1.43e-052132219608682
Pubmed

The quantitative level of T315I mutated BCR-ABL predicts for major molecular response to second-line nilotinib or dasatinib treatment in patients with chronic myeloid leukemia.

ABL1 BCR

1.43e-052132223065514
Pubmed

Bcr-Abl-mediated protection from apoptosis downstream of mitochondrial cytochrome c release.

ABL1 BCR

1.43e-052132215542838
Pubmed

Different BCR/Abl protein suppression patterns as a converging trait of chronic myeloid leukemia cell adaptation to energy restriction.

ABL1 BCR

1.43e-052132227852045
Pubmed

Fluorescent in situ hybridization analysis of Philadelphia chromosome-negative chronic myeloid leukemia with the bcr/abl fusion gene.

ABL1 BCR

1.43e-052132215481444
Pubmed

BCR-ABL gene expression is required for its mutations in a novel KCL-22 cell culture model for acquired resistance of chronic myelogenous leukemia.

ABL1 BCR

1.43e-052132220007699
Pubmed

BCR-ABL promotes the frequency of mutagenic single-strand annealing DNA repair.

ABL1 BCR

1.43e-052132219571320
Pubmed

Abr and Bcr are multifunctional regulators of the Rho GTP-binding protein family.

ABR BCR

1.43e-05213227479768
Pubmed

Butyrophilin 3A1 binds phosphorylated antigens and stimulates human γδ T cells.

RAG2 BTN3A1

1.43e-052132223872678
Pubmed

Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway.

ABL1 BCR

1.43e-052132219295548
Pubmed

Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation.

ABL1 BCR

1.43e-052132215735728
Pubmed

Constitutive association of BRCA1 and c-Abl and its ATM-dependent disruption after irradiation.

ABL1 BRCA1

1.43e-052132212024016
Pubmed

All human Na(+)-K(+)-ATPase alpha-subunit isoforms have a similar affinity for cardiac glycosides.

ATP1A1 ATP1A3

1.43e-052132211546672
Pubmed

Single-cell analysis of K562 cells: an imatinib-resistant subpopulation is adherent and has upregulated expression of BCR-ABL mRNA and protein.

ABL1 BCR

1.43e-052132224269846
Pubmed

The BCR-ABL1 transcript type influences response and outcome in Philadelphia chromosome-positive chronic myeloid leukemia patients treated frontline with imatinib.

ABL1 BCR

1.43e-052132228466557
Pubmed

BCR-ABL1 transcript doubling time as a predictor for treatment-free remission failure after imatinib discontinuation in chronic myeloid leukaemia in chronic phase.

ABL1 BCR

1.43e-052132234496035
Pubmed

Bis-three-way junction nanostructure and DNA machineries for ultrasensitive and specific detection of BCR/ABL fusion gene by chemiluminescence imaging.

ABL1 BCR

1.43e-052132227577607
Pubmed

Properties and expression of Na+/K+-ATPase α-subunit isoforms in the brain of the swamp eel, Monopterus albus, which has unusually high brain ammonia tolerance.

ATP1A1 ATP1A3

1.43e-052132224391932
Pubmed

Dual transcripts of BCR-ABL & different polymorphisms in chronic myeloid leukaemia patients.

ABL1 BCR

1.43e-052132227748288
Pubmed

Genetic and epigenetic silencing of microRNA-203 enhances ABL1 and BCR-ABL1 oncogene expression.

ABL1 BCR

1.43e-052132218538733
Pubmed

Cytogenetic, fluorescence in situ hybridization, and genomic array characterization of chronic myeloid leukemia with cryptic BCR-ABL1 fusions.

ABL1 BCR

1.43e-052132226186983
Pubmed

BCR-ABL transcript dynamics support the hypothesis that leukemic stem cells are reduced during imatinib treatment.

ABL1 BCR

1.43e-052132221903771
Pubmed

Emerging kinetics of BCR-ABL1 mutations and their effect on disease outcomes in chronic myeloid leukemia patients with imatinib failure.

ABL1 BCR

1.43e-052132223062378
Pubmed

The BCR-ABL1 kinase bypasses selection for the expression of a pre-B cell receptor in pre-B acute lymphoblastic leukemia cells.

ABL1 BCR

1.43e-052132214993251
Pubmed

Reciprocal t(9;22) ABL/BCR fusion proteins: leukemogenic potential and effects on B cell commitment.

ABL1 BCR

1.43e-052132219876398
Pubmed

Transient potent BCR-ABL inhibition is sufficient to commit chronic myeloid leukemia cells irreversibly to apoptosis.

ABL1 BCR

1.43e-052132219061839
Pubmed

Oral administration of pyrophosphate inhibits connective tissue calcification.

ENPP1 ABCC6

1.43e-052132228701330
Pubmed

Na+/K+ ATPase α1 and α3 isoforms are differentially expressed in α- and γ-motoneurons.

ATP1A1 ATP1A3

1.43e-052132223761886
Pubmed

Does pretreatment fluorescence in situ hybridization for BCR-ABL predict imatinib-associated hematologic toxicity in chronic myeloid leukemia?

ABL1 BCR

1.43e-052132221504383
Pubmed

Genetic heterogeneity of pseudoxanthoma elasticum: the Chinese signature profile of ABCC6 and ENPP1 mutations.

ENPP1 ABCC6

1.43e-052132225615550
Pubmed

An ultra-long circulating nanoparticle for reviving a highly selective BCR-ABL inhibitor in long-term effective and safe treatment of chronic myeloid leukemia.

ABL1 BCR

1.43e-052132232777451
Pubmed

Mechanisms of resistance to BCR-ABL and other kinase inhibitors.

ABL1 BCR

1.43e-052132223277196
Pubmed

Fluorescent and colorimetric RT-LAMP as a rapid and specific qualitative method for chronic myeloid leukemia diagnosis.

ABL1 BCR

1.43e-052132234971572
Pubmed

Therapeutic targeting of BCR-ABL: prognostic markers of response and resistance mechanism in chronic myeloid leukaemia.

ABL1 BCR

1.43e-052132222471662
Pubmed

Growth factor independence and BCR/ABL transformation: promise and pitfalls of murine model systems and assays.

ABL1 BCR

1.43e-052132210450747
Pubmed

T315I mutation in Ph-positive acute lymphoblastic leukemia is associated with a highly aggressive disease phenotype: three case reports.

ABL1 BCR

1.43e-052132222593461
Pubmed

Cell sorting enables interphase fluorescence in situ hybridization detection of low BCR-ABL1 producing stem cells in chronic myeloid leukaemia patients beyond deep molecular remission.

ABL1 BCR

1.43e-052132224903628
Pubmed

Frequency of BCR-ABL fusion transcripts in Serbian patients with chronic myeloid leukemia.

ABL1 BCR

1.43e-052132221674858
Pubmed

The family of human Na+,K+-ATPase genes. A partial nucleotide sequence related to the alpha-subunit.

ATP1A1 ATP1A3

1.43e-05213223030810
Pubmed

Correlation of p210 BCR-ABL transcript variants with clinical, parameters and disease outcome in 45 chronic myeloid leukemia patients.

ABL1 BCR

1.43e-052132227273956
Pubmed

Targeting the SH2-kinase interface in Bcr-Abl inhibits leukemogenesis.

ABL1 BCR

1.43e-052132222000011
Pubmed

BCR-ABL1-positive microvesicles malignantly transform human bone marrow mesenchymal stem cells in vitro.

ABL1 BCR

1.43e-052132228836580
Pubmed

The BCR-ABL1 T315I mutation and additional genomic aberrations are dominant genetic lesions associated with disease progression in patients with chronic myelogenous leukemia resistant to tyrosine kinase inhibitor therapy.

ABL1 BCR

1.43e-052132223289360
Pubmed

Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow.

ABL1 BCR

1.43e-05213229808572
Pubmed

The novel anticancer agent JNJ-26854165 is active in chronic myeloid leukemic cells with unmutated BCR/ABL and T315I mutant BCR/ABL through promoting proteosomal degradation of BCR/ABL proteins.

ABL1 BCR

1.43e-052132227999193
Pubmed

Generalized Arterial Calcification of Infancy

ENPP1 ABCC6

1.43e-052132225392903
Pubmed

Emergence of BCR-ABL kinase domain mutations associated with newly diagnosed chronic myeloid leukemia: a meta-analysis of clinical trials of tyrosine kinase inhibitors.

ABL1 BCR

1.43e-052132225615000
Pubmed

Preclinical development of a novel BCR-ABL T315I inhibitor against chronic myeloid leukemia.

ABL1 BCR

1.43e-052132231837444
Pubmed

Fused transcript of abl and bcr genes in chronic myelogenous leukaemia.

ABL1 BCR

1.43e-05213222989692
Pubmed

Mechanisms of genesis of variant translocation in chronic myeloid leukemia are not correlated with ABL1 or BCR deletion status or response to imatinib therapy.

ABL1 BCR

1.43e-052132218406870
Pubmed

Analysis and comparison of clinicohematological parameters and molecular and cytogenetic response of two Bcr/Abl fusion transcripts.

ABL1 BCR

1.43e-052132219048492
Pubmed

The alpha subunit of the epithelial sodium channel in the mouse: developmental regulation of its expression.

SCNN1A ATP1A1

1.43e-05213229284273
Pubmed

Expression of BCR-ABL1 oncogene relative to ABL1 gene changes overtime in chronic myeloid leukemia.

ABL1 BCR

1.43e-052132218082628
Pubmed

The putative oncogene CEP72 inhibits the mitotic function of BRCA1 and induces chromosomal instability.

BRCA1 CEP72

1.43e-052132226300001
Pubmed

Results of allogeneic hematopoietic stem cell transplantation for chronic myelogenous leukemia patients who failed tyrosine kinase inhibitors after developing BCR-ABL1 kinase domain mutations.

ABL1 BCR

1.43e-052132221156844
Pubmed

Molecular biology of bcr-abl1-positive chronic myeloid leukemia.

ABL1 BCR

1.43e-052132218827185
Pubmed

Frequency of BCR-ABL gene mutations in Polish patients with chronic myeloid leukemia treated with imatinib: a final report of the MAPTEST study.

ABL1 BCR

1.43e-052132220010464
Pubmed

Role of BCR/ABL gene-expression levels in determining the phenotype and imatinib sensitivity of transformed human hematopoietic cells.

ABL1 BCR

1.43e-052132217347407
Pubmed

BCR/ABL modifies the kinetics and fidelity of DNA double-strand breaks repair in hematopoietic cells.

ABL1 BCR

1.43e-052132216297667
Pubmed

Involvement of primary mesenchymal precursors and hematopoietic bone marrow cells from chronic myeloid leukemia patients by BCR-ABL1 fusion gene.

ABL1 BCR

1.43e-052132224779036
Pubmed

Functional dichotomy between NKG2D and CD28-mediated co-stimulation in human CD8+ T cells.

KLRK1 CD28

1.43e-052132220844584
Pubmed

Molecular analysis of the BCR-ABL1 kinase domain in chronic-phase chronic myelogenous leukemia treated with tyrosine kinase inhibitors in practice: study by the Nagasaki CML Study Group.

ABL1 BCR

1.43e-052132224262285
Pubmed

BCR-ABL kinase domain mutations, including 2 novel mutations in imatinib resistant Malaysian chronic myeloid leukemia patients-Frequency and clinical outcome.

ABL1 BCR

1.43e-052132224456693
Pubmed

BCR sequences essential for transformation by the BCR-ABL oncogene bind to the ABL SH2 regulatory domain in a non-phosphotyrosine-dependent manner.

ABL1 BCR

1.43e-05213221712671
Pubmed

Prevalence of BCR-ABL T315I Mutation in Different Chronic Myeloid Leukemia patients Categories.

ABL1 BCR

1.43e-052132235234007
Pubmed

Kinase domain mutations of BCR-ABL identified at diagnosis before imatinib-based therapy are associated with progression in patients with high Sokal risk chronic phase chronic myeloid leukemia.

ABL1 BCR

1.43e-052132220038234
Pubmed

Iron-inhibited autophagy via transcription factor ZFP27 in Parkinson's disease.

ZNF585A ZNF585B

1.43e-052132237668106
Pubmed

Exon 7 deletion in the bcr-abl gene is frequent in chronic myeloid leukemia patients and is not correlated with resistance against imatinib.

ABL1 BCR

1.43e-052132221045136
Pubmed

Feasibility of tumor‑derived exosome enrichment in the onco‑hematology leukemic model of chronic myeloid leukemia.

ABL1 BCR

1.43e-052132231638195
GeneFamilySolute carriers

SLC37A1 SLC5A7 SLC35G6 SLC16A6 SLC25A40 SLCO2A1 SLC25A10 SLC6A20 SLC9A7 SLC45A1

4.69e-053959610752
GeneFamilyButyrophilins|V-set domain containing|C2-set domain containing

BTN3A2 BTN3A1 BTN3A3

6.30e-0515963458
GeneFamilyAdenosine receptors|V-set domain containing

PSG2 PSG11 BTN3A2 BTN3A1 BTN3A3 CD28

2.32e-04163966590
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD2 CSMD3 SVEP1 CFHR4

2.38e-04579641179
GeneFamilyV-type ATPases

ATP6V0A1 ATP6V0A4 ATP6V0A2

2.38e-0423963415
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A1 ATP1A3

5.76e-0479621208
GeneFamilyCD molecules|V-set domain containing|Pregnancy specific glycoproteins

PSG2 PSG11

1.49e-03119621315
GeneFamilyATPase phospholipid transporting

ATP10B ATP9B

2.80e-03159621210
GeneFamilyDyneins, axonemal

DNAH2 DNAH1

3.60e-0317962536
GeneFamilyPleckstrin homology domain containing|Rho guanine nucleotide exchange factors|C2 domain containing

ABR BCR PREX1

5.21e-0366963722
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SULF2 STARD9 SLCO2A1 SCN4A PREX1

5.49e-091921309c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SULF2 STARD9 SLCO2A1 SCN4A PREX1

6.87e-091971309412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ABL1 ENPP1 BCR NDRG2 ADGRG6 SULF2 SLC9A7 ATP6V0A2

9.51e-0819113083480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellCOPD-Myeloid-cDC1|COPD / Disease state, Lineage and Cell class

FLT1 ABL1 ENPP1 BCR NDRG2 SULF2 SLC9A7 ATP6V0A2

9.90e-081921308bd3d00b094d92463b06023361a71240851a542b8
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SULF2 SLCO2A1 SCN4A PREX1

1.07e-071941308e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SULF2 STARD9 SLCO2A1 PREX1

1.21e-071971308cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellControl-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ABL1 ENPP1 BCR NDRG2 SULF2 SLC9A7 ATP6V0A2

1.18e-061841307c6affa0b12510363258f65e46bf2d47bf4a8e75f
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ENPP1 NDRG2 ADGRG6 GOT1L1 SULF2 SLC9A7 ATP6V0A2

1.18e-061841307667846c422cfa27e949a24844a305df859cb6760
ToppCellBAL-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 NDRG2 ADGRG6 GOT1L1 SULF2 SLC9A7 ATP6V0A2

1.18e-061841307a6f8b42982ec0cf44b950a2cd9715d068eec4ecb
ToppCell5'-Adult-LymphNode-Endothelial-blood_vessel_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 MYCT1 CFI APOLD1 SLCO2A1 SCN4A PKP1

1.46e-061901307141266bf411ea675fbf889b20c1b08673c45ff95
ToppCellCF-Epithelial|CF / Disease state, Lineage and Cell class

ATP10B NDRG2 TMPRSS11B ADGRG6 EPHA2 SCNN1A MUC4

1.62e-061931307518901c2e36a79c6189cd0d9e6d36dbd4f56a79c
ToppCellCF-Epithelial-Epithelial_cell|CF / Disease state, Lineage and Cell class

ATP10B NDRG2 TMPRSS11B ADGRG6 EPHA2 SCNN1A MUC4

1.62e-0619313074e3dda27c71b7fdac90d081f0d8e9ca3a8ea7820
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SULF2 SLCO2A1 PREX1

1.62e-06193130752e918884877b6659cdca0496390e440f73694a9
ToppCellsaliva-Mild-Moderate_progression_d12-25|saliva / Compartment, severity and other cell annotations on 10x 3' data (130k)

NDRG2 BTN3A2 TMPRSS11B MS4A1 EPHA2 MUC4 ZNF121

1.74e-0619513076eb123cbea7bcadbdef086a8c230f0a73caf4930
ToppCellCOVID-19-kidney-AQP1+PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

FLT1 MYCT1 ADGRB3 APOLD1 STARD9 SLCO2A1 PREX1

1.92e-0619813078689090bce9ab6e8f122426a404037e572c6713b
ToppCellLPS_only-Epithelial_airway-airway_epithelial|LPS_only / Treatment groups by lineage, cell group, cell type

ATP10B NDRG2 TF DNAH1 PKP1 CIBAR2 MUC4

1.92e-061981307e035380578c01b0243bfef29ca9b50cc17cce771
ToppCellLPS_only-Epithelial_airway|LPS_only / Treatment groups by lineage, cell group, cell type

ATP10B NDRG2 TF DNAH1 PKP1 CIBAR2 MUC4

1.92e-061981307ba090210392e001a3f7bdf09371b3f0e0c8c7ef3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 STARD9 SLCO2A1 PREX1

1.92e-0619813070a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellTracheal-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Duct|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ATP10B EPHA2 SLCO2A1 ATP6V0A4 SCPEP1 ATP1A1 MUC4

1.99e-061991307527aae1d9d37a50deefc01fc0c064a53673681bd
ToppCell3'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-CLP|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC37A1 RAG2 BCR MS4A1 SLC9A7 ZNF726

1.19e-051731306b367b62309389e8b6a65de83c2434dc8ec905985
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Squamous|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ATP10B NDRG2 TMPRSS11B SCNN1A PKP1 MUC4

1.23e-0517413060a4721248ec89bc98ebe119de6e19fbfca8b5098
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHIA DTX1 RALGPS2 MS4A1 SCN4A SLC9A7

1.31e-051761306077f3fe5e3482ea3f639d789bd3d584161b36c02
ToppCellfacs-Heart-LA-24m-Lymphocytic-B_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHIA DTX1 RALGPS2 MS4A1 SCN4A SLC9A7

1.31e-051761306fc2ba468677b19b55130c1f06737f40300cd9d2e
ToppCelldroplet-Tongue-nan-24m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDRG2 FDFT1 EPHA2 ATP6V0A4 SCNN1A PKP1

1.40e-051781306a3176b2b335db22bb0fb71aafa5d7a287809396e
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SMG1 ATP10B EPHA2 SCNN1A UBA6 MUC4

1.45e-0517913066e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 APOLD1 STARD9 SLCO2A1

1.49e-05180130616728b9a1c52097e3a460534be71a476ecc54f0f
ToppCell3'_v3-Lung-Myeloid_Dendritic-DC1|Lung / Manually curated celltypes from each tissue

ENPP1 CFI NDRG2 ADGRG6 SULF2 SLC9A7

1.64e-051831306e4cbd39575b5a4612d9934532e3bad63286f8aa5
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ABL1 ENPP1 BCR SULF2 SLC9A7 ATP6V0A2

1.69e-05184130642d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-3|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CATIP CHIA EPHA2 SLCO2A1 CIBAR2 GPC5

1.80e-05186130629c79b5a29907d4f3f87ad2ca04840c0f15b7d4e
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ABL1 ENPP1 BCR NDRG2 SULF2 SLC9A7

1.80e-051861306962c2dada19185628ead77c32fcb07fa95114247
ToppCellControl-Myeloid-cDC1|World / Disease state, Lineage and Cell class

ABL1 ENPP1 NDRG2 SULF2 SLC9A7 ATP6V0A2

1.80e-0518613063de803dee3ef10eb85a2b47d3f93385214e5b0ff
ToppCellControl-Myeloid-cDC1|Control / Disease state, Lineage and Cell class

ABL1 ENPP1 NDRG2 SULF2 SLC9A7 ATP6V0A2

1.80e-051861306b05c394aa3573ba855abc3066739ca193883b0c3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 STARD9 SLCO2A1 PREX1

1.85e-05187130635c382c0aabd46906113e5db30ea24bb8e658899
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Cortical_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PGAP6 ATP6V0A4 SCNN1A GPC5 CFAP70 ATP1A1

1.85e-0518713067ea8731288e2a99f45e3958590ee1d76f49ae888
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

ABL1 ENPP1 BCR NDRG2 SULF2 SLC9A7

1.91e-05188130647bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCell5'-GW_trimst-2-LargeIntestine-Endothelial-blood_vessel_EC-venous_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 MYCT1 DUSP7 APOLD1 SLCO2A1 SCN4A

1.91e-0518813060026c9479b30fb39daa91cfa220a88f9c9e65fe7
ToppCellIPF-Myeloid-cDC1|IPF / Disease state, Lineage and Cell class

ABL1 ENPP1 BCR NDRG2 SULF2 SLC9A7

1.91e-0518813062331a2bae1383820d598e93aa86c75b101069bac
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYCT1 BCR APOLD1 EPHA2 SLCO2A1

1.97e-051891306d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYCT1 BCR APOLD1 EPHA2 SLCO2A1

1.97e-051891306476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYCT1 BCR APOLD1 EPHA2 SLCO2A1

1.97e-0518913063fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 BRCA1 APOLD1 STARD9 SLCO2A1 POLQ

2.02e-05190130631de1727822e9818652946dfb962daee77ffad68
ToppCellBL-critical-LOC-Epithelial-Squamous|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ATP10B NDRG2 TMPRSS11B EPHA2 SCNN1A MUC4

2.09e-0519113063f9b8c4fb72ae6f3167b187e6715c4dcb3159f98
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam_____kidney_distal_convoluted_tubule_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NDRG2 ATP6V0A4 SCNN1A ATP1A1 IL17RD ATP4A

2.15e-0519213066fb56d062c35617b18b927704bf5fba894faed81
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 STARD9 SLCO2A1

2.15e-05192130628eb3a5728e8901bcb5ba12f6b009f41b065fa37
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SLCO2A1 PREX1

2.21e-0519313062e72309607902dabe3218888b22a77fe941f3570
ToppCell5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 MCHR1 MYCT1 ADGRG6 APOLD1 SLCO2A1

2.21e-051931306c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 APOLD1 SLCO2A1 GPC5

2.21e-0519313061f978e102a029a6beb10913052cd0a20c7253e8e
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A7 ATP10B EPHA2 SCNN1A PKP1 MUC4

2.21e-05193130622ebc3f586eb0aabc5785e468c88d7416c624ff4
ToppCelldroplet-Mammary_Gland-nan-21m-Epithelial-luminal_progenitor_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC5A7 ATP10B SULF2 EPHA2 PKP1 MUC4

2.28e-0519413060ef63abcfd057079a9a6f8b27404ff521d44845d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 STARD9 SLCO2A1 PREX1

2.28e-051941306f76808666fb875fc787751cbfd924d9be20a8192
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PRUNE2 ENPP1 FAM135B ADGRG6 PTPRD LPIN2

2.28e-05194130670185c0b8e0f4e896645b17a243482ba3cdf4a5d
ToppCellCTRL-Epithelial-Epithelial_cell|CTRL / Disease state, Lineage and Cell class

ATP10B NDRG2 TMPRSS11B EPHA2 SCNN1A MUC4

2.28e-0519413062bc4deaf2a01a39809fc323962fce4286835209c
ToppCell10x5'-bone_marrow-Myeloid_Dendritic|bone_marrow / Manually curated celltypes from each tissue

ENPP1 TLR7 CFI NDRG2 SULF2 EPHA2

2.28e-051941306768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCellCTRL-Epithelial|CTRL / Disease state, Lineage and Cell class

ATP10B NDRG2 TMPRSS11B EPHA2 SCNN1A MUC4

2.28e-05194130649dcb31427f370692308f939e23992925708abb7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 STARD9 SLCO2A1 PREX1

2.28e-051941306f5706ab6bc803606c4640ddd606617e4e797ccc9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 STARD9 SLCO2A1 PREX1

2.28e-051941306a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCell5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FLT1 MYCT1 CFI ADGRG6 SULF2 SLCO2A1

2.34e-05195130681a98ebb0d43f416f9a8bba580531dc0cfea8f74
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SLCO2A1 PREX1

2.34e-05195130677e47d2e8b3eb7f7c9620369ccaf87581f923bdb
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 STARD9 SLCO2A1

2.41e-0519613068ad8efb631164b46f0c082572270188e5ead20bf
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 SULF2 SLCO2A1 PREX1

2.41e-051961306023312af38f816a44b407e0daa32590d953caf99
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NDRG2 ATP6V0A4 SCNN1A SCPEP1 GPC5 ATP1A1

2.41e-051961306f40d10ea7714067585493fdc89744714aa427de8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 STARD9 SLCO2A1 PREX1

2.41e-051961306ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Endothelial-Endothelial_mature-Endo_capilar-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FLT1 MYCT1 CFI ADGRG6 APOLD1 SLCO2A1

2.41e-051961306889c9fed857f64664ca1f47fcec9fecb15ed103c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 STARD9 SLCO2A1

2.41e-0519613069606ea7e42f707e69ea891b3521037613b9675f5
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ADGRB3 APOLD1 STARD9 SLCO2A1 PREX1

2.48e-0519713060f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCell3'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 MYCT1 DTX1 MS4A1 SLC6A20 PREX1

2.48e-0519713061614bc5f41fd2c8385e58ed6b87ef1536421f29a
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SLCO2A1 PREX1

2.55e-05198130607701c73137947ed4a27e225975329235bbb8734
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SLCO2A1 PREX1

2.55e-05198130631ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 APOLD1 SLCO2A1 PREX1

2.55e-0519813061378c6d4ceb84b42fdd6556be3296df7a8059e6e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 APOLD1 SLCO2A1 PREX1

2.55e-051981306451003a21162eeae90739fdb502bb50b362d80c8
ToppCellAT2_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

CHIA MEGF9 FDFT1 SLC6A20 LSS ATP1A1

2.55e-051981306893036558a9ad86b57f9e735df35812e9d18739e
ToppCell5'-Adult-LymphNode-Endothelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MYCT1 CFI APOLD1 SLCO2A1 SCN4A PKP1

2.55e-051981306d7e15e61b6018e4c36461c9471ee29601929925c
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell-Epi-Squamous|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NDRG2 TMPRSS11B ADGRG6 EPHA2 SCNN1A MUC4

2.55e-05198130672d91bd0c727ecadc41e023a16c9326158db1b7b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 MYCT1 ADGRB3 APOLD1 SLCO2A1 PREX1

2.55e-051981306440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-squamous_epithelial_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

NDRG2 TMPRSS11B ADGRG6 EPHA2 SCNN1A MUC4

2.55e-051981306441608034c787e55691558a480dcd07e37419138
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ABR MYCT1 ADGRB3 SLCO2A1 PREX1

2.55e-051981306fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCellLPS_only-Epithelial_airway-airway_epithelial-Airway-Club|LPS_only / Treatment groups by lineage, cell group, cell type

ATP10B NDRG2 TF PKP1 CIBAR2 MUC4

2.63e-051991306165ac94b2d56072ad43358b5127d77555221e2d8
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAH2 ATP10B TF DNAH1 PKP1 CIBAR2

2.63e-05199130660919c2af31d39a2d36d7bc432e43dab2a4e05fb
ToppCellLPS_anti-TNF-Epithelial_airway|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

DNAH2 ATP10B TF DNAH1 PKP1 CIBAR2

2.63e-0519913066aca164bbbb961f34b1e6f1857f91ade5c059405
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

NDRG2 SCNN1A PKP1 SCPEP1 ATP1A1 MUC4

2.70e-05200130697f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCelldistal-3-Endothelial-Vein|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLT1 MYCT1 CFI ADGRG6 SULF2 SLCO2A1

2.70e-0520013063a5c85bad2e7a9ecf55d90acb04178a343b3f5fd
ToppCelldistal-Endothelial-Vein|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLT1 MYCT1 CFI ADGRG6 SULF2 SLCO2A1

2.70e-0520013066acf7afe122f81a95c4c66f4d0878d997b57127a
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

NDRG2 SCNN1A PKP1 SCPEP1 ATP1A1 MUC4

2.70e-052001306ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellP03-Hematopoietic|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TLR7 KLRK1 MS4A1 CD28 ATP1A3

5.88e-0514113054a856521520ea73291f4730fe94c5de88c2b6f0c
ToppCellPND01-Immune-Immune_Lymphocytic_T/NK|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RAG2 KLRK1 MS4A1 CD28 SLC9A7

7.40e-051481305b78dac56b333bf901136ccafb0999f345e978f51
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ENPP1 CFI NDRG2 ADGRG6 CIDEC

8.93e-0515413055967a0a33456d5930fc492a700ebb015ac050abb
ToppCell343B-Myeloid-Dendritic-cDC1|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

ENPP1 CFI FAM135B ADGRG6 SLC45A1

8.93e-05154130571d33b5dbfab5820e3daddb01806a69116ba8008
ToppCellPBMC-Severe-Myeloid-cDC-cDC-cDC_11|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ENPP1 CFI NDRG2 ADGRG6 CIDEC

9.21e-051551305fab281db4c275d51240b122be78713c839ba5a95
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 ADGRB3 FNDC7 SLCO2A1 PREX1

9.21e-05155130559035d792c26d870a8b097939e97fa47859ba68c
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 FNDC7 SULF2 SLCO2A1 PREX1

9.49e-051561305ea9223bb6450b22df11efa1705ab72dab005244a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-Degenerative_Endothelial_Cell-Degenerative_Peritubular_Capilary_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FLT1 FNDC7 SULF2 SLCO2A1 PREX1

9.49e-051561305586b5509074c4cc359e9e31a968c2ded71c994ca
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYCT1 CFI APOLD1 CIDEC

9.78e-051571305b6ecf1d8c6a465ff31cbc181e00ea88b76b38e19
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYCT1 CFI APOLD1 CIDEC

9.78e-05157130501ad5cbaf91010e79216e1fb37b7b890618c5f28
ToppCellfacs-GAT-Fat-24m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 CHIA APOLD1 CD28 MUC4

9.78e-051571305c4a0b6c95d353691fd2846002ce4bc7c2b0edd1c
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_B-ABC_aged-B_naive|lymph-node_spleen / Manually curated celltypes from each tissue

CHIA DTX1 RALGPS2 MS4A1 SCN4A

1.01e-0415813057098847804dd90fa1dd74536e4e90f989b630fe4
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CHIA ABCC6 SCNN1A GPC5 ATP1A1

1.04e-041591305e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-B_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RALGPS2 BRCA1 MS4A1 CEP72 LSS

1.04e-04159130574655c22e9fdd88e3052b9dfb954c8fb678bd2d8
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_venous_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FLT1 MYCT1 CFI ADGRG6 SLCO2A1

1.07e-04160130533050dc646762dc7e9dcc4a12c618e1ba1ce5a4d
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-1|TCGA-Kidney / Sample_Type by Project: Shred V9

FLT1 MYCT1 APOLD1 SCN4A CDON

1.10e-0416113056cacae4a759ace763597ee394cff498dc5d96f74
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLT1 MYCT1 DNAH2 APOLD1 POLQ

1.13e-041621305465cb483f41023d6125ea147e16f404d8e8dc9bb
DrugNadide [53-84-9]; Up 200; 6uM; MCF7; HT_HG-U133A

PRUNE2 ATP9B NDRG2 BTN3A1 SLCO2A1 SLC9A7 LSS CAMSAP1 MUC4

2.16e-0619713196091_UP
DrugAC1NSN3X

ASIC5 KLRK1 SCN4A SCNN1A TAT

1.47e-05541315CID005366189
DrugAC1MBZB6

SLCO2A1 ATP1A1 ATP1A3

1.52e-0591313CID002733620
DrugGlycopyrrolate [596-51-0]; Up 200; 10uM; PC3; HT_HG-U133A

ATP6V0A1 MEGF9 CIDEC ATP6V0A4 SCNN1A SLC9A7 LSS CAMSAP1

1.90e-0519713183687_UP
DrugNa-Z

ATP6V0A1 MS4A1 ATP6V0A4 ATP6V0A2

2.92e-05311314CID005497094
Drugpyrethrin

ASIC5 FDFT1 SCN4A SCNN1A

2.92e-05311314CID000011442
DrugRH-3421

ASIC5 SCN4A SCNN1A

2.97e-05111313CID000108039
Drugchloroacetylajmaline

ASIC5 SCN4A SCNN1A

2.97e-05111313CID000038681
DrugAluminium

TF ATP1A1

3.29e-0521312DB01370
DrugAG568

ABL1 BCR

3.29e-0521312CID005487625
Drugresiniferatoxin

SLC5A7 ASIC5 MS4A1 SCN4A SCNN1A

3.94e-05661315CID000104826
DrugRo 22-9194

ASIC5 SCN4A SCNN1A

3.94e-05121313CID000129209
DrugAG957

FLT1 ABL1 BCR ABCC6

4.77e-05351314CID000002064
DrugAC1LCJM3

ASIC5 SCN4A SCNN1A

5.10e-05131313CID000631640
DrugCID6432355

ASIC5 SCN4A SCNN1A

5.10e-05131313CID006432355
DrugAC1NRB3N

ATP6V0A1 MS4A1 CD28 ATP6V0A2

5.97e-05371314CID005288242
Druglorcainide

ASIC5 SCN4A SCNN1A

6.47e-05141313CID000042883
Drugoctylguanidine

ASIC5 SCN4A SCNN1A

6.47e-05141313CID000030621
DrugN-bromoacetamide

SLC5A7 ASIC5 SCN4A SCNN1A

6.64e-05381314CID000004353
Drugoxovanadium

ATP6V0A1 ATP6V0A4 SCNN1A ATP1A1 ATP1A3 CDON

6.91e-051201316CID000024411
DrugSMIC

ABL1 BCR KLRK1

8.05e-05151313CID005272749
Drugtrimethyloxonium

ASIC5 SCN4A SCNN1A

8.05e-05151313CID000093245
DrugAC1L1W4O

ASIC5 SCN4A SCNN1A

8.05e-05151313CID000036625
Drug2-phenylpyrimidine

ABL1 BCR

9.82e-0531312CID000593578
Drug3 SP

FDFT1 CDON

9.82e-0531312CID006852188
Drugpurmorphamine

ABL1 BCR

9.82e-0531312ctd:C470893
DrugFerric phosphate dihydrate

FLT1 TF

9.82e-0531312CID011615510
DrugPD 173958

ABL1 BCR

9.82e-0531312CID005330525
Drughydroxymethyltrioxsalen

ATP6V0A1 ENPP1 ATP6V0A2

9.87e-05161313CID000104953
Drug4-anilinoquinazoline

FLT1 ABL1 BCR

9.87e-05161313CID000324081
Drug1,3,4-oxadiazole

FLT1 CHIA HDAC4

9.87e-05161313CID000097428
Drugtrimethaphan

SLC25A40 SCNN1A SLC9A7 ATP1A1 ATP1A3

1.05e-04811315CID000023576
Diseaseautosomal recessive osteopetrosis 1 (implicated_via_orthology)

ATP6V0A1 ATP6V0A4 ATP6V0A2

7.92e-0751283DOID:0110942 (implicated_via_orthology)
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A1 ATP1A3 ATP4A

2.76e-0671283DOID:0060178 (implicated_via_orthology)
Diseaserenal tubular acidosis (implicated_via_orthology)

ATP6V0A1 ATP6V0A4 ATP6V0A2

4.39e-0681283DOID:14219 (implicated_via_orthology)
Diseasenervous system disease (implicated_via_orthology)

ATP1A1 ATP1A3 ATP4A

1.70e-05121283DOID:863 (implicated_via_orthology)
Diseasearterial calcification of infancy (is_implicated_in)

ENPP1 ABCC6

1.87e-0521282DOID:0050644 (is_implicated_in)
Diseasearterial calcification of infancy (implicated_via_orthology)

ENPP1 ABCC6

1.87e-0521282DOID:0050644 (implicated_via_orthology)
DiseaseChronic myelogenous leukemia, BCR-ABL1 positive

ABL1 BCR

1.87e-0521282cv:C0279543
DiseaseArterial calcification of infancy

ENPP1 ABCC6

1.87e-0521282cv:C1859727
DiseaseArterial calcification of infancy

ENPP1 ABCC6

1.87e-0521282C1859727
Diseasepseudoxanthoma elasticum (implicated_via_orthology)

ENPP1 ABCC6

1.87e-0521282DOID:2738 (implicated_via_orthology)
DiseaseLEUKEMIA, CHRONIC MYELOID

ABL1 BCR

1.87e-0521282608232
DiseaseTransitional cell carcinoma of bladder

FLT1 BCR

1.11e-0441282C0279680
DiseasePseudoxanthoma Elasticum

ENPP1 ABCC6

1.11e-0441282C0033847
DiseaseRestless Legs Syndrome

TF PTPRD

1.85e-0451282C0035258
Diseasecalcium measurement

HDAC4 MCHR1 DNAH2 ABCC6 APOLD1 TMEM131 ATP1A1 ASCC3 ATP1A3 POLQ

4.25e-0462812810EFO_0004838
Diseaseage-related macular degeneration

CFI GRM5 CFHR4 SCPEP1

6.20e-04891284EFO_0001365
DiseaseAtypical hemolytic-uremic syndrome

CFI CFHR4

6.59e-0491282cv:C2931788
DiseaseHemolytic-uremic syndrome

CFI CFHR4

6.59e-0491282cv:C0019061
Diseaseforced expiratory volume

HDAC4 RALGPS2 RDH14 SVEP1 ADGRG6 CEP72 SCN4A GPC5 IL17RD PREX1 CDON

6.67e-0478912811EFO_0004314
DiseaseIntellectual Disability

HDAC4 TMX2 BRCA1 FDFT1 LSS ATP1A1 ASCC3 TAT

7.65e-044471288C3714756
DiseaseCongenital myasthenic syndrome

SLC5A7 SCN4A

8.21e-04101282cv:C0751882
DiseaseSkin Abnormalities

FDFT1 LSS

1.41e-03131282C0037268
Diseaseabdominal adipose tissue measurement

SCN4A ATP1A1 ATP1A3

1.59e-03531283EFO_0803316
DiseaseCocaine-Related Disorders

HDAC4 ATP9B GRM5 FDFT1

1.72e-031171284C0236736
DiseaseCongenital total cataract

EPHA2 LSS

2.15e-03161282C0266539
DiseaseMyasthenic Syndromes, Congenital, Slow Channel

SLC5A7 SCN4A

2.15e-03161282C0751885
DiseasePre-Eclampsia

FLT1 SCNN1A

2.15e-03161282C0032914
DiseaseCocaine Abuse

HDAC4 ATP9B GRM5 FDFT1

2.31e-031271284C0009171
DiseaseCongenital Myasthenic Syndromes, Postsynaptic

SLC5A7 SCN4A

2.43e-03171282C0751883
DiseaseKuhnt-Junius degeneration (is_implicated_in)

FLT1 CFI

2.43e-03171282DOID:10873 (is_implicated_in)
Diseaserespiratory syncytial virus infectious disease (is_marker_for)

TLR7 CD28

2.73e-03181282DOID:1273 (is_marker_for)
DiseaseCongenital Myasthenic Syndromes, Presynaptic

SLC5A7 SCN4A

3.04e-03191282C0751884
Diseaseautism spectrum disorder, schizophrenia

SHMT2 BTN3A2 BTN3A1 TMX2 GID4 MPHOSPH9

3.10e-033271286EFO_0003756, MONDO_0005090
DiseaseCocaine Dependence

HDAC4 ATP9B GRM5 FDFT1

3.20e-031391284C0600427
Diseaseschizophrenia (implicated_via_orthology)

SHMT2 GRM5 CSMD3

3.25e-03681283DOID:5419 (implicated_via_orthology)
Diseasesarcopenia

PTPRD FDFT1

3.37e-03201282EFO_1000653
Diseasecerebellum white matter volume change measurement, age at assessment

ADGRB3 GOT1L1

3.37e-03201282EFO_0008007, EFO_0021498
Diseaseage-related macular degeneration, COVID-19

CFI CFHR4 SLC6A20

3.39e-03691283EFO_0001365, MONDO_0100096
Diseasenephrotic syndrome

PTPRD CD28 GPC5

3.68e-03711283EFO_0004255
Diseaseserum alanine aminotransferase measurement, response to combination chemotherapy

HDAC4 CSMD2 CFHR4

3.68e-03711283EFO_0004735, EFO_0007965
DiseasePrecursor B-cell lymphoblastic leukemia

ABL1 BCR

3.71e-03211282C1292769
Diseasechronic myeloid leukemia (is_implicated_in)

ABL1 BCR

3.71e-03211282DOID:8552 (is_implicated_in)
DiseaseAttention Deficit Disorder

GRM5 PTPRD

4.07e-03221282C0041671
DiseaseMinimal Brain Dysfunction

GRM5 PTPRD

4.07e-03221282C1321905

Protein segments in the cluster

PeptideGeneStartEntry
FSSLGTYCLEQLYLQ

URB2

666

Q14146
FLTTCYQLLGYLQKG

URB2

941

Q14146
NRNGKSYLFLLSSDY

ABR

431

Q12979
DSGYSYQCILFSNLI

C21orf140

206

B9A014
TEKYFGQFCSLLAAY

CIBAR2

21

Q6ZTR7
LISNCSKFYGNRFYE

CFI

491

P05156
VTASDSGKYLCYFQD

BTN3A3

116

O00478
YTLIYSCQEGFSLKG

CSMD2

3211

Q7Z408
FKVYYEELQSSSCGN

CSMD3

166

Q7Z407
YFCNDGYRLSSKELT

CSMD3

2656

Q7Z407
VNLSCKYSYNLFSRE

CD28

36

P10747
VTASDSGKYLCYFQD

BTN3A1

116

O00481
SSNLYCTLEVDSFGY

BCR

926

P11274
KDLSCSNFSLLAYQF

ADGRB3

76

O60242
FFCSQSLSKNFGIYD

GOT1L1

241

Q8NHS2
GYFLSISDSKCLLNN

ADGRG6

221

Q86SQ4
SCSNAAFALKQYYLR

ARID2

81

Q68CP9
LQLGSAYQLTCYFTN

CHIA

16

Q9BZP6
TALESLNLYYNCISS

CEP72

76

Q9P209
LNLYYNCISSLAEVF

CEP72

81

Q9P209
CYDQAKQLVLSTGYL

SLC25A10

181

Q9UBX3
QYCYSIQSLFLGILS

MS4A1

181

P11836
EFSNEYLNKCFYLTL

CAMSAP1

291

Q5T5Y3
YKSGQNSECYNLSTF

ATP10B

1181

O94823
GNILLYYTAKACKNS

NBEAL1

826

Q6ZS30
LIHLSAGSNKYYCNE

RAG2

466

P55895
EALGSCLNNKYSEGY

SHMT2

86

P34897
QTASLFYNCEGKQYL

GUF1

121

Q8N442
NFLSENKSISYYGCA

OR5I1

86

Q13606
GENQYTFCYNIKSDS

KBTBD3

306

Q8NAB2
SSKCQELANYYFGFN

RDM1

111

Q8NG50
CGRNASIALYNSVYF

APOLD1

186

Q96LR9
LYNIFSAFGNILSCK

PABPC1L2A

106

Q5JQF8
LNVSTLKAYFRCDGY

MUC4

5291

Q99102
YNGLLILSCTFYAFK

GRM5

746

P41594
YNLSARCFGYLTKQL

HDAC4

946

P56524
SGLYNITFKYDNCTT

IL17RD

51

Q8NFM7
NTLSFLKSNADLCYG

TAT

341

P17735
LKKSCTLYVGNLSFY

NCBP2

36

P52298
KQAENYTSILFCSTY

GPC5

116

P78333
NYSTDLYGSKGIFTC

FNDC7

656

Q5VTL7
GDQTFVLCSKYENYS

HERC3

371

Q15034
IITGCFSYYQEAKSS

ATP1A1

141

P05023
SLGCYVSSLAFLNEY

ATP9B

1076

O43861
FCLQYGAALIYTSVK

DYNC1LI2

261

O43237
KTCYKYLNQTSRSFA

FDFT1

41

P37268
LYASSFKGYIENCST

KLRK1

191

P26718
FNKSCAISYTSYRNI

LSS

696

P48449
GYGTFCISELNLYKS

MPHOSPH9

46

Q99550
ETCKEGFYLNYTSGL

MEGF9

236

Q9H1U4
YTGDSQAQELCLYLT

TUBGCP2

366

Q9BSJ2
CSFYKNNTKVSYGFL

ENPP1

726

P22413
LSYDTLQYCDFLGSG

PGAP6

601

Q9HCN3
KSEGYNDLSLYNLFL

PANX1

321

Q96RD7
DLSSLGFCYLIYFNS

DTX1

141

Q86Y01
KTGYYSSFFECQSAI

OTOP2

121

Q7RTS6
GFYYICFQKSAASIE

GID4

256

Q8IVV7
CAFQLDTGLEYANSY

BRCA1

91

P38398
QQLLGALDYSFLCAY

SLC37A1

96

P57057
TYSLYSNVCRSLFEK

DNAH1

3506

Q9P2D7
CLYQTNSKLYESLTY

CHD6

1631

Q8TD26
LSYELNCSGKYFAFK

CFAP70

556

Q5T0N1
GASSCKETFNLYYAE

EPHA2

111

P29317
CYIDSFKSRYTGINQ

POLQ

2411

O75417
SLNSSLLGYYQCLAN

CDON

86

Q4KMG0
YLFGFQVKSLYLCDA

GJE1

136

A6NN92
LKSNLNTYGERFCYL

DPY19L4

236

Q7Z388
YLYLGCAKDSTNLDV

DUSP7

251

Q16829
VLEAGKNLYTFCVSY

ABL1

1056

P00519
TEGKLCYLTYQNLGF

CATIP

201

Q7Z7H3
YLNNSTLLDCEFFGK

ASIC5

176

Q9NY37
VTASDSGKYLCYFQD

BTN3A2

116

P78410
QSYYELQGSKYVTCS

CFHR4

241

Q92496
LYNAAISLGYANSCL

MCHR1

361

Q99705
IITGCFSYYQEAKSS

ATP1A3

131

P13637
CYSAKASYLFQQDKF

GADL1

356

Q6ZQY3
ISECYQFKFKYTNNG

HORMAD1

111

Q86X24
CFLYQLSQKTGLQYF

FAM135B

1291

Q49AJ0
YSGITSLCKLYSALA

DNAH2

2281

Q9P225
YYSGENLDLSCFANS

PSG11

251

Q9UQ72
QNKSDCFYQTYSSGV

SCNN1A

231

P37088
LCDYYQSKKFAGSSA

SLC45A1

686

Q9Y2W3
CFGYYQEFKSTNIIA

ATP4A

156

P20648
SNISSKAQYYAICFL

CEBPZ

431

Q03701
DTYVLAFAICYKLNS

PTCD2

201

Q8WV60
ATYCVRTFALYKNGS

PTPRD

1491

P23468
AALCGTQLFYYAAKS

RALGPS2

486

Q86X27
QSKIYSRAFYSCAAG

SLC16A6

446

O15403
SQIISYSGCLAQLYF

OR1N2

106

Q8NGR9
QNRYSFYSTCSGQKA

PKP1

181

Q13835
NICISYLAKYLFESG

SLC5A7

491

Q9GZV3
FLSYKCSDYSASNLG

PRUNE2

941

Q8WUY3
LFAGKFYYCINTTTS

SCN4A

1181

P35499
YFTCYDQLSALLRSK

SLC25A40

121

Q8TBP6
LTYHDVGLNYKSCFQ

NDRG2

66

Q9UN36
LLYAGFQSLYVVSSC

ABCC6

1096

O95255
YYATNSCKNFSELPL

SCPEP1

56

Q9HB40
YEGLCKNYFSLAVLQ

MYCT1

6

Q8N699
LSCSAYFTFLKLNAG

SMG1

1746

Q96Q15
CTFSKQLLAALGYRY

PREX1

1336

Q8TCU6
RLCSGYYSLNQSFVE

SHISAL2B

6

A6NKW6
KLSFCGSNIISYFYC

OR8K1

171

Q8NGG5
YNKSFCYSRSKLANI

RDH14

211

Q9HBH5
AYTKSGYCVNRFSSL

SNUPN

141

O95149
NYSLDSLSCVYAKAL

STARD9

1106

Q9P2P6
YCSDGYSLADNSQLL

SVEP1

2046

Q4LDE5
SIYGFKATFNYENCL

SLC6A20

296

Q9NP91
TALGCKAYEALYNFS

ASCC3

1311

Q8N3C0
IGCLNVKATFYDTYS

CIDEC

156

Q96AQ7
LQLCQLLYSAYFKSS

SLCO2A1

41

Q92959
IYADLSLKYNCTGLN

TMX2

176

Q9Y320
SFLQNAAKLYATVYC

UBA6

756

A0AVT1
CKQYGEGLSYLISFQ

ZNF700

336

Q9H0M5
LNIYDLCNKFIAYST

VPS11

311

Q9H270
LNQYFGYSGAFKCLK

TF

201

P02787
DNKICNASYAYSGFV

TMPRSS11B

331

Q86T26
CNVCGKLFNELSYYT

RBAK

541

Q9NYW8
GLALYLNTLSADFCY

TMTC2

11

Q8N394
SSYQQKSISLYRGNC

TMEM131

91

Q92545
FLPASQQACAKLYSY

TMEM214

521

Q6NUQ4
QQACAKLYSYSLQGY

TMEM214

526

Q6NUQ4
YICTEYGKVFSNNSN

ZNF585B

326

Q52M93
FYALLNVLSIGCAYS

SLC35G6

106

P0C7Q6
SVNESCYKYGQTLDL

TLR7

486

Q9NYK1
YICTEYGKVFSNNSN

ZNF585A

326

Q6P3V2
GLIYNDCFSKSLNIF

ATP6V0A1

461

Q93050
YTGLIYNDCFSKSLN

ATP6V0A4

461

Q9HBG4
CEEYGKAFNQSSNYT

ZNF726

231

A6NNF4
NECGKAYNRFYLLTK

ZNF121

371

P58317
YRSGDNLYLSCFANS

PSG2

251

P11465
GQLSDKFYYTDCLFF

SLC9A7

241

Q96T83
TAQANHTGFYSCKYL

FLT1

96

P17948
NSINSTKTNDYGYCS

VN1R3

156

Q9BXE9
VGLLKNSRFYNYTLC

SULF2

161

Q8IWU5
SVYTGLIYNDCFSKS

ATP6V0A2

461

Q9Y487
LIYNDCFSKSVNLFG

ATP6V0A2

466

Q9Y487
HSINENGYKFLYCSA

LPIN2

721

Q92539