Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	structural constituent of cytoskeleton	BFSP2 SPTB	3.64e-03	130	14	2	GO:0005200
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	FADS1 AGMO	7.91e-03	194	14	2	GO:0016705
Pubmed	Variants at DGKB/TMEM195, ADRA2A, GLIS3 and C2CD4B loci are associated with reduced glucose-stimulated beta cell function in middle-aged Danish people.	FADS1 AGMO	9.91e-06	12	14	2	20419449
Pubmed	New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk.	FADS1 AGMO	2.85e-05	20	14	2	20081858
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	PRPF40A FAM186A FAT2	1.04e-04	234	14	3	36243803
Pubmed	Interactome Analysis of Human Phospholipase D and Phosphatidic Acid-Associated Protein Network.	HSP90AB4P GCN1 FADS1	1.80e-04	282	14	3	35007762
Pubmed	The finished DNA sequence of human chromosome 12.	GCN1 FAM186A	3.48e-04	69	14	2	16541075
Disease	BMI-adjusted fasting blood glucose measurement	FADS1 AGMO	5.26e-05	23	14	2	EFO_0008036
Disease	HbA1c measurement	FAM186A SPTB FADS1 AGMO	2.26e-04	675	14	4	EFO_0004541
Disease	glycerophospholipid measurement	SPATA20 FADS1	2.43e-04	49	14	2	EFO_0007630
Disease	body mass index, fasting blood glucose measurement	FADS1 AGMO	2.63e-04	51	14	2	EFO_0004340, EFO_0004465
Disease	HOMA-B	FADS1 AGMO	3.06e-04	55	14	2	EFO_0004469
Disease	hemoglobin A1 measurement	SPTB FADS1 AGMO	1.71e-03	520	14	3	EFO_0007629

Protein segments in the cluster

Peptide	Gene	Start	Entry
FHRMAHEVNIMWAGH	AGMO	131	Q6ZNB7
HEWQDEFSHIMAMTD	FBXO4	301	Q9UKT5
ENTLHDAKHWHDMEL	BFSP2	346	Q13515
DDLHMDMLEEQHHQA	PDZRN3	521	Q9UPQ7
CVHHVWIMDSFDDLM	HSP90AB4P	306	Q58FF6
HVNDHEWHSILVEEM	FAT2	3846	Q9NYQ8
EMPHHSEEEEEWMAQ	GCN1	991	Q92616
HLKVEDMQWAHREHT	GRM8	496	O00222
LHEHGQLHSMSSWME	PRPF40A	621	O75400
HHMDELHISMIQWMV	AXDND1	696	Q5T1B0
WVTQMNHIPMHIDHD	FADS1	336	O60427
NHIPMHIDHDRNMDW	FADS1	341	O60427
LSEMTLMDVDEHHHW	FAM186A	141	A6NE01
LMDVDEHHHWIAQME	FAM186A	146	A6NE01
HWCHMMEEESFQNEE	SPATA20	111	Q8TB22
DMLHSIDWMDEIKAH	SPTB	536	P11277