Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionprotein serine/threonine kinase binding

BIRC8 XIAP APP

6.64e-0524663GO:0120283
GeneOntologyMolecularFunctionubiquitin protein ligase activity

BIRC8 TRIM51 LTN1 TRIM63 XIAP ASB4 TRIM52

2.23e-04372667GO:0061630
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

BIRC8 TRIM51 LTN1 TRIM63 XIAP ASB4 TRIM52

3.36e-04398667GO:0061659
GeneOntologyMolecularFunctionTFIID-class transcription factor complex binding

ERCC1 ZNHIT6

4.76e-0410662GO:0001094
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

BIRC8 TRIM51 LTN1 TRIM63 XIAP ASB4 TRIM52

9.34e-04473667GO:0004842
GeneOntologyBiologicalProcessregulation of apoptosis involved in tissue homeostasis

BIRC8 XIAP

2.84e-053642GO:0060785
GeneOntologyBiologicalProcesspositive regulation of MDA-5 signaling pathway

DDX60 ANKRD17

5.66e-054642GO:1900245
GeneOntologyCellularComponentgrowth cone lamellipodium

APBB1 APP

2.51e-053612GO:1990761
GeneOntologyCellularComponentgrowth cone filopodium

APBB1 APP

5.01e-054612GO:1990812
GeneOntologyCellularComponentooplasm

PRKCA NLRP5

1.25e-046612GO:1990917
GeneOntologyCellularComponentacrosomal membrane

TEKT3 TRIP11 CCDC136

1.85e-0438613GO:0002080
GeneOntologyCellularComponentouter acrosomal membrane

TEKT3 TRIP11

2.32e-048612GO:0002081
GeneOntologyCellularComponentU4 snRNP

SNRPB SNRPN

6.40e-0413612GO:0005687
GeneOntologyCellularComponentU2-type prespliceosome

SNRPB SNRPN

1.24e-0318612GO:0071004
GeneOntologyCellularComponentprespliceosome

SNRPB SNRPN

1.24e-0318612GO:0071010
GeneOntologyCellularComponentperinuclear region of cytoplasm

RAB38 BIRC8 AFTPH PDE7A APBB1 PRKCA XIAP SCEL APP

1.47e-03934619GO:0048471
HumanPhenoAplasia/Hypoplasia of the sacrum

FANCB WNT7A TRIP11

2.04e-0517173HP:0008517
DomainsnRNP-assoc_SmB/SmN

SNRPB SNRPN

1.08e-052622IPR017131
DomainBIR

BIRC8 XIAP

3.00e-048622SM00238
Domain-

BIRC8 XIAP

3.00e-0486221.10.1170.10
DomainBIR

BIRC8 XIAP

3.00e-048622PF00653
DomainBIR_REPEAT_2

BIRC8 XIAP

3.00e-048622PS50143
DomainBIR_rpt

BIRC8 XIAP

3.00e-048622IPR001370
DomainBIR_REPEAT_1

BIRC8 XIAP

3.00e-048622PS01282
DomainDrf_GBD

FMNL3 FMNL2

3.85e-049622PF06371
DomainFH3_dom

FMNL3 FMNL2

3.85e-049622IPR010472
DomainGTPase-bd

FMNL3 FMNL2

3.85e-049622IPR010473
DomainDrf_FH3

FMNL3 FMNL2

3.85e-049622PF06367
DomainDrf_FH3

FMNL3 FMNL2

3.85e-049622SM01139
DomainDrf_GBD

FMNL3 FMNL2

3.85e-049622SM01140
DomainZF_RING_1

BIRC8 TRIM51 LTN1 TRIM63 XIAP TRIM52

4.02e-04291626PS00518
DomainZF_RING_2

BIRC8 TRIM51 LTN1 TRIM63 XIAP TRIM52

4.56e-04298626PS50089
DomainRING

BIRC8 TRIM51 LTN1 TRIM63 XIAP TRIM52

5.15e-04305626SM00184
DomainGBD/FH3_dom

FMNL3 FMNL2

5.85e-0411622IPR014768
DomainGBD_FH3

FMNL3 FMNL2

5.85e-0411622PS51232
DomainZnf_RING

BIRC8 TRIM51 LTN1 TRIM63 XIAP TRIM52

7.30e-04326626IPR001841
DomainZnf_RING/FYVE/PHD

BIRC8 TRIM51 LTN1 TRIM63 XIAP KDM2A TRIM52

7.92e-04459627IPR013083
Domainzf-C3HC4

BIRC8 TRIM51 LTN1 TRIM63 TRIM52

8.63e-04223625PF00097
DomainAnk

ANKRD36B ANKRD19P ANKRD17 ASB4 ANKRD36

9.54e-04228625PF00023
DomainFH2

FMNL3 FMNL2

1.11e-0315622PS51444
DomainFH2_Formin

FMNL3 FMNL2

1.11e-0315622IPR015425
DomainFH2

FMNL3 FMNL2

1.11e-0315622PF02181
DomainFH2

FMNL3 FMNL2

1.11e-0315622SM00498
DomainPoly(ADP-ribose)pol_cat_dom

PARP4 PARP9

1.43e-0317622IPR012317
DomainPARP_CATALYTIC

PARP4 PARP9

1.43e-0317622PS51059
DomainPARP

PARP4 PARP9

1.43e-0317622PF00644
Domain-

PARP4 PARP9

1.43e-03176223.90.228.10
DomainANK

ANKRD36B ANKRD19P ANKRD17 ASB4 ANKRD36

1.46e-03251625SM00248
DomainANK_REPEAT

ANKRD36B ANKRD19P ANKRD17 ASB4 ANKRD36

1.51e-03253625PS50088
DomainANK_REP_REGION

ANKRD36B ANKRD19P ANKRD17 ASB4 ANKRD36

1.54e-03254625PS50297
DomainBBOX

TRIM51 TRIM63 TRIM52

1.56e-0369623SM00336
Domain-

TRIM51 TRIM63 TRIM52

1.70e-03716234.10.45.10
DomainAnkyrin_rpt

ANKRD36B ANKRD19P ANKRD17 ASB4 ANKRD36

1.76e-03262625IPR002110
Domainzf-B_box

TRIM51 TRIM63 TRIM52

1.77e-0372623PF00643
DomainSm

SNRPB SNRPN

1.79e-0319622SM00651
DomainLSM

SNRPB SNRPN

1.79e-0319622PF01423
DomainLSM_dom_euk/arc

SNRPB SNRPN

1.79e-0319622IPR001163
DomainZF_BBOX

TRIM51 TRIM63 TRIM52

2.39e-0380623PS50119
DomainDAPIN

NLRP9 NLRP5

2.40e-0322622PS50824
DomainPYRIN

NLRP9 NLRP5

2.40e-0322622PF02758
DomainDAPIN

NLRP9 NLRP5

2.40e-0322622IPR004020
DomainLSM_dom

SNRPB SNRPN

2.40e-0322622IPR010920
DomainPYRIN

NLRP9 NLRP5

2.40e-0322622SM01289
DomainZnf_B-box

TRIM51 TRIM63 TRIM52

2.47e-0381623IPR000315
DomainZnf_C3HC4_RING-type

TRIM51 LTN1 TRIM63 TRIM52

2.56e-03172624IPR018957
DomainNACHT

NLRP9 NLRP5

2.62e-0323622PS50837
DomainNACHT_NTPase

NLRP9 NLRP5

2.62e-0323622IPR007111
DomainWGR_domain

PARP4 PARP9

2.85e-0324622IPR008893
DomainARM-type_fold

FMNL3 XPO5 LTN1 MEI1 FMNL2

5.31e-03339625IPR016024
DomainAnk_2

ANKRD36B ANKRD17 ASB4 ANKRD36

5.66e-03215624PF12796
Domain-

ANKRD36B ANKRD17 ASB4 ANKRD36

9.27e-032486241.25.40.20
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PARP4 ATP8B4 TRPM3 LTN1 KDM2A ARHGAP35 FMNL2 DENND3 EXOC4

6.49e-0749370915368895
Pubmed

Tyr(682) in the intracellular domain of APP regulates amyloidogenic APP processing in vivo.

APBB1 APP

3.99e-06270221103325
Pubmed

Overexpression of the X-Linked Inhibitor of Apoptosis Protein (XIAP) in Neurons Improves Cell Survival and the Functional Outcome after Traumatic Spinal Cord Injury.

BIRC8 XIAP

3.99e-06270236769152
Pubmed

X-linked inhibitor of apoptosis deficiency in the TRAMP mouse prostate cancer model.

BIRC8 XIAP

3.99e-06270218259199
Pubmed

XIAP regulates intracellular ROS by enhancing antioxidant gene expression.

BIRC8 XIAP

3.99e-06270218692482
Pubmed

Deficiency of XIAP leads to sensitization for Chlamydophila pneumoniae pulmonary infection and dysregulation of innate immune response in mice.

BIRC8 XIAP

3.99e-06270220427267
Pubmed

Essential roles for Fe65, Alzheimer amyloid precursor-binding protein, in the cellular response to DNA damage.

APBB1 APP

3.99e-06270217121854
Pubmed

XIAP overexpression in islet beta-cells enhances engraftment and minimizes hypoxia-reperfusion injury.

BIRC8 XIAP

3.99e-06270215888033
Pubmed

Regulation of beta-amyloid secretion by FE65, an amyloid protein precursor-binding protein.

APBB1 APP

3.99e-06270210075692
Pubmed

Association of AICD and Fe65 with Hirano bodies reduces transcriptional activation and initiation of apoptosis.

APBB1 APP

3.99e-06270220133016
Pubmed

The reduction of XIAP is associated with inflammasome activation in RPE: implications for AMD pathogenesis.

BIRC8 XIAP

3.99e-06270231438981
Pubmed

The transcriptional activity of the APP intracellular domain-Fe65 complex is inhibited by activation of the NF-kappaB pathway.

APBB1 APP

3.99e-06270212653567
Pubmed

XIAP overexpression promotes bladder cancer invasion in vitro and lung metastasis in vivo via enhancing nucleolin-mediated Rho-GDIβ mRNA stability.

BIRC8 XIAP

3.99e-06270229250796
Pubmed

Genomic organization and primary characterization of miap-3: the murine homologue of human X-linked IAP.

BIRC8 XIAP

3.99e-0627029205126
Pubmed

Endoproteolytic cleavage of FE65 converts the adaptor protein to a potent suppressor of the sAPPalpha pathway in primates.

APBB1 APP

3.99e-06270215647266
Pubmed

Increased X-linked inhibitor of apoptosis protein (XIAP) expression exacerbates experimental autoimmune encephalomyelitis (EAE).

BIRC8 XIAP

3.99e-06270218687476
Pubmed

Lack of X-linked inhibitor of apoptosis protein leads to increased apoptosis and tissue loss following neonatal brain injury.

BIRC8 XIAP

3.99e-06270219570023
Pubmed

IFN-gamma sensitizes MIN6N8 insulinoma cells to TNF-alpha-induced apoptosis by inhibiting NF-kappaB-mediated XIAP upregulation.

BIRC8 XIAP

3.99e-06270216154537
Pubmed

XIAP protects oligodendrocytes against cell death in vitro but has no functional role in toxic demyelination.

BIRC8 XIAP

3.99e-06270222065417
Pubmed

XIAP-deficiency leads to delayed lobuloalveolar development in the mammary gland.

BIRC8 XIAP

3.99e-06270215540113
Pubmed

Nuclear localization of amyloid-β precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis.

APBB1 APP

3.99e-06270228323844
Pubmed

Inability to resolve specific infection generates innate immunodeficiency syndrome in Xiap-/- mice.

BIRC8 XIAP

3.99e-06270225190756
Pubmed

The human FE65 gene: genomic structure and an intronic biallelic polymorphism associated with sporadic dementia of the Alzheimer type.

APBB1 APP

3.99e-0627029799084
Pubmed

The beta-amyloid precursor protein functions as a cytosolic anchoring site that prevents Fe65 nuclear translocation.

APBB1 APP

3.99e-06270211085987
Pubmed

Identification of an Xiap-like pseudogene on mouse chromosome 7.

BIRC8 XIAP

3.99e-06270219956646
Pubmed

The cardiac form of the tissue-specific SmN protein is identical to the brain and embryonic forms of the protein.

SNRPB SNRPN

3.99e-0627028510173
Pubmed

Deficiency in X-linked inhibitor of apoptosis protein promotes susceptibility to microbial triggers of intestinal inflammation.

BIRC8 XIAP

3.99e-06270234739342
Pubmed

FMNL formins boost lamellipodial force generation.

FMNL3 FMNL2

3.99e-06270228327544
Pubmed

IL-6 receptor blockade corrects defects of XIAP-deficient regulatory T cells.

BIRC8 XIAP

3.99e-06270229386580
Pubmed

[The clinical signifcance of expression of ERCC1 and PkCalpha in non-small cell lung cancer].

ERCC1 PRKCA

3.99e-06270220673527
Pubmed

Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice.

BIRC8 XIAP

3.99e-06270218755525
Pubmed

Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice.

BIRC8 XIAP

3.99e-06270212667469
Pubmed

A strategy to identify protein-N-myristoylation-dependent phosphorylation reactions of cellular proteins by using Phos-tag SDS-PAGE.

FMNL3 FMNL2

3.99e-06270231751425
Pubmed

Protein N-myristoylation is required for cellular morphological changes induced by two formin family proteins, FMNL2 and FMNL3.

FMNL3 FMNL2

3.99e-06270222790947
Pubmed

Structure of the intracellular domain of the amyloid precursor protein in complex with Fe65-PTB2.

APBB1 APP

3.99e-06270218833287
Pubmed

Regulation of FE65 nuclear translocation and function by amyloid beta-protein precursor in osmotically stressed cells.

APBB1 APP

3.99e-06270218468999
Pubmed

Transgenic mice overexpressing XIAP in neurons show better outcome after transient cerebral ischemia.

BIRC8 XIAP

3.99e-06270212812761
Pubmed

Deletion Of XIAP reduces the severity of acute pancreatitis via regulation of cell death and nuclear factor-κB activity.

BIRC8 XIAP

3.99e-06270228300832
Pubmed

Role of X-linked inhibitor of apoptosis (XIAP) in frozen and thawed dormant and normal-hatched murine blastocysts.

BIRC8 XIAP

3.99e-06270229605544
Pubmed

Overexpression of XIAP inhibits cisplatin-induced hair cell loss.

BIRC8 XIAP

3.99e-06270235026350
Pubmed

Effects of XIAP on high fat diet-induced hepatic steatosis: a mechanism involving NLRP3 inflammasome and oxidative stress.

BIRC8 XIAP

3.99e-06270231841118
Pubmed

Genomic organization of the X-linked inhibitor of apoptosis and identification of a novel testis-specific transcript.

BIRC8 XIAP

3.99e-06270211597143
Pubmed

XIAP regulates cytosol-specific innate immunity to Listeria infection.

BIRC8 XIAP

3.99e-06270218769721
Pubmed

XIAP inhibition of β-cell apoptosis reduces the number of islets required to restore euglycemia in a syngeneic islet transplantation model.

BIRC8 XIAP

3.99e-06270221099289
Pubmed

ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.

BIRC8 XIAP

3.99e-06270216115895
Pubmed

XIAP deficiency in hematopoietic recipient cells drives donor T-cell activation and GvHD in mice.

BIRC8 XIAP

3.99e-06270230585320
Pubmed

Eliminating encephalitogenic T cells without undermining protective immunity.

BIRC8 XIAP

3.99e-06270224277699
Pubmed

IAP proteins: blocking the road to death's door.

BIRC8 XIAP

3.99e-06270212042762
Pubmed

Modification Effect of PARP4 and ERCC1 Gene Polymorphisms on the Relationship between Particulate Matter Exposure and Fasting Glucose Level.

PARP4 ERCC1

3.99e-06270235627777
Pubmed

Analysis of inhibitor of apoptosis protein family expression during mammary gland development.

BIRC8 XIAP

3.99e-06270220584313
Pubmed

XIAP inhibits gentamicin-induced hair cell damage and ototoxicity through the caspase-3/9 pathway.

BIRC8 XIAP

3.99e-06270233713642
Pubmed

Characterization of XIAP-deficient mice.

BIRC8 XIAP

3.99e-06270211313486
Pubmed

XIAP Knockdown in Alcohol-Associated Liver Disease Models Exhibits Divergent in vitro and in vivo Phenotypes Owing to a Potential Zonal Inhibitory Role of SMAC.

BIRC8 XIAP

3.99e-06270234025452
Pubmed

Spatiotemporal Regulation of FMNL2 by N-Terminal Myristoylation and C-Terminal Phosphorylation Drives Rapid Filopodia Formation.

PRKCA FMNL2

3.99e-06270236979484
Pubmed

X-linked inhibitor of apoptosis regulates T cell effector function.

BIRC8 XIAP

3.99e-06270218025200
Pubmed

A macromolecular complex involving the amyloid precursor protein (APP) and the cytosolic adapter FE65 is a negative regulator of axon branching.

APBB1 APP

3.99e-06270217383198
Pubmed

Fe65 stimulates proteolytic liberation of the beta-amyloid precursor protein intracellular domain.

APBB1 APP

3.99e-06270217855370
Pubmed

Inhibitor of apoptosis protein (IAP) profiling in experimental autoimmune encephalomyelitis (EAE) implicates increased XIAP in T lymphocytes.

BIRC8 XIAP

3.99e-06270218055022
Pubmed

Skeletal muscle differentiation evokes endogenous XIAP to restrict the apoptotic pathway.

BIRC8 XIAP

3.99e-06270219333375
Pubmed

Concerted regulation and molecular evolution of the duplicated SNRPB'/B and SNRPN loci.

SNRPB SNRPN

3.99e-06270210556313
Pubmed

The intracellular domain of the beta-amyloid precursor protein is stabilized by Fe65 and translocates to the nucleus in a notch-like manner.

APBB1 APP

1.20e-05370211544248
Pubmed

S-nitrosylation of XIAP compromises neuronal survival in Parkinson's disease.

BIRC8 XIAP

1.20e-05370219273858
Pubmed

The beta-amyloid precursor protein APP is tyrosine-phosphorylated in cells expressing a constitutively active form of the Abl protoncogene.

APBB1 APP

1.20e-05370211279131
Pubmed

Molecular cloning of ILP-2, a novel member of the inhibitor of apoptosis protein family.

BIRC8 XIAP

1.20e-05370211390657
Pubmed

XIAP-mediated degradation of IFT88 disrupts HSC cilia to stimulate HSC activation and liver fibrosis.

BIRC8 XIAP

1.20e-05370238351372
Pubmed

Phosphorylation of FE65 at threonine 579 by GSK3β stimulates amyloid precursor protein processing.

APBB1 APP

1.20e-05370228963516
Pubmed

The APP intracellular domain forms nuclear multiprotein complexes and regulates the transcription of its own precursor.

APBB1 APP

1.20e-05370215331662
Pubmed

XIAP decreases caspase-12 cleavage and calpain activity in spinal cord of ALS transgenic mice.

BIRC8 XIAP

1.20e-05370216566922
Pubmed

Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms.

APBB1 APP

1.20e-05370230664241
Pubmed

In silico identification and structural features of six new genes similar to MATER specifically expressed in the oocyte.

NLRP9 NLRP5

1.20e-05370215474461
Pubmed

Quercetin ameliorates XIAP deficiency-associated hyperinflammation.

BIRC8 XIAP

1.20e-05370235687753
Pubmed

XIAP and survivin as therapeutic targets for radiation sensitization in preclinical models of lung cancer.

BIRC8 XIAP

1.20e-05370215258565
Pubmed

Interaction of the phosphotyrosine interaction/phosphotyrosine binding-related domains of Fe65 with wild-type and mutant Alzheimer's beta-amyloid precursor proteins.

APBB1 APP

1.20e-0537029045663
Pubmed

Identification and characterization of human FMNL1, FMNL2 and FMNL3 genes in silico.

FMNL3 FMNL2

1.20e-05370212684686
Pubmed

Loss of XIAP facilitates switch to TNFα-induced necroptosis in mouse neutrophils.

BIRC8 XIAP

1.20e-05370227735938
Pubmed

MiR-96 promotes myocardial infarction-induced apoptosis by targeting XIAP.

BIRC8 XIAP

1.20e-05370233752931
Pubmed

Anti-apoptotic protein BRE/BRCC45 attenuates apoptosis through maintaining the expression of caspase inhibitor XIAP in mouse Lewis lung carcinoma D122 cells.

BIRC8 XIAP

1.20e-05370224395041
Pubmed

The X-linked inhibitor of apoptosis regulates long-term depression and learning rate.

BIRC8 XIAP

1.20e-05370227189977
Pubmed

Phenotypic differences between mice deficient in XIAP and SAP, two factors targeted in X-linked lymphoproliferative syndrome (XLP).

BIRC8 XIAP

1.20e-05370219595300
Pubmed

Intact Regulatory T-Cell Function but Defective Generation of IL-17A-Producing CD4+ T Cells in XIAP Deficiency.

BIRC8 XIAP

1.20e-05370226825770
Pubmed

Characterization of an amyloid precursor protein-binding protein Fe65L2 and its novel isoforms lacking phosphotyrosine-interaction domains.

APBB1 APP

1.20e-05370212153398
Pubmed

Selective vulnerability in Alzheimer's disease: amyloid precursor protein and p75(NTR) interaction.

APBB1 APP

1.20e-05370219334058
Pubmed

Interaction of checkpoint kinase 1 and the X-linked inhibitor of apoptosis during mitosis.

BIRC8 XIAP

1.20e-05370214759516
Pubmed

Dexras1 interacts with FE65 to regulate FE65-amyloid precursor protein-dependent transcription.

APBB1 APP

1.20e-05370218922798
Pubmed

Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein.

APBB1 APP

1.20e-05370221650223
Pubmed

Formin-like 2 Promotes β1-Integrin Trafficking and Invasive Motility Downstream of PKCα.

PRKCA FMNL2

1.20e-05370226256210
Pubmed

miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia.

BIRC8 XIAP

1.20e-05370221709246
Pubmed

Inhibitor of apoptosis proteins are required for effective fusion of autophagosomes with lysosomes.

BIRC8 XIAP

1.20e-05370229743550
Pubmed

β-Elemene enhances susceptibility to cisplatin in resistant ovarian carcinoma cells via downregulation of ERCC-1 and XIAP and inactivation of JNK.

ERCC1 XIAP

1.20e-05370223817665
Pubmed

Subcellular localization of a promoter and an inhibitor of apoptosis (Smac/DIABLO and XIAP) during brain ischemia/reperfusion.

BIRC8 XIAP

1.20e-05370212395105
Pubmed

FAIM-L regulation of XIAP degradation modulates Synaptic Long-Term Depression and Axon Degeneration.

BIRC8 XIAP

1.20e-05370227767058
Pubmed

Phosphorylation of LRP1 regulates the interaction with Fe65.

APBB1 APP

1.20e-05370221968187
Pubmed

A comparison of snRNP-associated Sm-autoantigens: human N, rat N and human B/B'.

SNRPB SNRPN

1.20e-0537022522186
Pubmed

Differential involvement of protein kinase C alpha and epsilon in the regulated secretion of soluble amyloid precursor protein.

PRKCA APP

1.20e-05370215233804
Pubmed

The Sept4 septin locus is required for sperm terminal differentiation in mice.

BIRC8 XIAP

1.20e-05370215737931
Pubmed

Protein tyrosine phosphatase receptor type Z is involved in hippocampus-dependent memory formation through dephosphorylation at Y1105 on p190 RhoGAP.

PTPRZ1 ARHGAP35

1.20e-05370216513268
Pubmed

Phosphorylation of FE65 Ser610 by serum- and glucocorticoid-induced kinase 1 modulates Alzheimer's disease amyloid precursor protein processing.

APBB1 APP

1.20e-05370226188042
Pubmed

X-linked inhibitor of apoptosis protein negatively regulates neuronal differentiation through interaction with cRAF and Trk.

BIRC8 XIAP

1.20e-05370223928917
Pubmed

Involvement of the Edar signaling in the control of hair follicle involution (catagen).

BIRC8 XIAP

1.20e-05370217148670
Pubmed

Caspase-3 Regulates YAP-Dependent Cell Proliferation and Organ Size.

BIRC8 XIAP

1.20e-05370229775577
Cytoband4q34

CEP44 WDR17

2.22e-0556924q34
Cytoband6p21.2

C6orf89 DNAH8

1.36e-03366926p21.2
CytobandEnsembl 112 genes in cytogenetic band chr2q11

ANKRD36B ANKRD36 ANKRD36C

1.62e-03153693chr2q11
CytobandEnsembl 112 genes in cytogenetic band chr4q34

CEP44 WDR17

3.85e-0361692chr4q34
GeneFamilyAnkyrin repeat domain containing

ANKRD36B ANKRD17 ASB4 ANKRD36 ANKRD36C ANKRD18B

2.84e-05242456403
GeneFamilyRing finger proteins|Baculoviral IAP repeat containing|Caspase recruitment domain containing

BIRC8 XIAP

1.68e-048452419
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP4 PARP9

8.04e-0417452684
GeneFamilyRing finger proteins|Tripartite motif containing|ARF GTPase family

TRIM51 TRIM63 TRIM52

1.70e-039545359
GeneFamilyPyrin domain containing|Pyrin and HIN domain family

NLRP9 NLRP5

1.75e-0325452994
GeneFamilyNLR family

NLRP9 NLRP5

1.75e-0325452666
GeneFamilyRing finger proteins

TRIM51 LTN1 TRIM63 TRIM52

4.78e-0327545458
CoexpressionGSE32986_UNSTIM_VS_GMCSF_AND_CURDLAN_LOWDOSE_STIM_DC_DN

GVINP1 WNT7A APBB1 ARHGAP35 CCDC180 EXOC4

1.35e-05200686M8620
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 PDE7A WNT7A APBB1 SCEL APP DENND3

2.07e-081966879790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 PDE7A WNT7A APBB1 SCEL APP DENND3

2.07e-08196687b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

SEC14L3 PDE7A WNT7A APBB1 SCEL APP DENND3

2.07e-08196687484bbc6b1f58bc260964babb949d14f5df101393
ToppCell(1)_T_cells-(1)_T_CD4_naive|(1)_T_cells / Spleen cell shreds - cell class (v1) and cell subclass (v1)

ANKRD36B ZNHIT6 PRKCA ANKRD36 ANKRD36C TRIP11

5.37e-07195686d3fa551bc6f5ee5890af1040415e61ecd5d46201
ToppCell(10)_Ciliated-(2)_GFP_FOXI1|(10)_Ciliated / shred by cell type by condition

ANKRD36B MAP4K5 XIAP PARP9 ANKRD36 TRIP11

6.05e-0719968661b1ed2db71b96157b92b7535d1955a4033098da
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 ATP8B4 PRKCA SCEL DYRK4

6.80e-061736855d7c53c6d1cdd385e44b79b82faec901747d1736
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 ATP8B4 PRKCA SCEL DYRK4

6.99e-061746859eab43885496b8586f8ec5b4bcb1fd5b209218e5
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 WNT7A SCEL APP DENND3

1.10e-05191685ce76b156b153a2c7c9f2fb8e563b69c81073fbe5
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 WNT7A SCEL APP DENND3

1.10e-05191685c006f5a6e3a32b79ac99a78304bdd5116fc0d5e0
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 WNT7A SCEL APP DENND3

1.13e-05192685790282d4232311df3dac4ad97c80fc53443beccc
ToppCellPND10-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 WNT7A SCEL APP DENND3

1.13e-05192685b2d9bffccd6264b4f12d88a0780646ee0b41969f
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

ANKRD36B PRKCA KDM2A ANKRD36 ANKRD36C

1.13e-0519268547646d7e4990be85072987f92bf18d52f8da752e
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

PDE7A TRPM3 ANKRD17 PRKCA EXOC4

1.13e-05192685e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

MAP4K5 XIAP PARP9 ANKRD36 TRIP11

1.34e-05199685c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(08)_Brush+PNEC-(2)_GFP_FOXI1|(08)_Brush+PNEC / shred by cell type by condition

ANKRD17 XIAP PARP9 TRIP11

5.93e-05138684817e3f639604ea95adae01e8685ffaa2e0aff7a8
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1_-_meso|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SEC14L3 PDE7A WNT7A SCEL

8.19e-051506846a13e4c4b9c9e54a5016573a37132465ec1c8f99
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

ANKRD36B ANKRD36 ANKRD36C TRIM52

8.40e-05151684999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NLRP9 TRPM3 ASB4 SNRPN

9.07e-05154684cd99428c282d566b5dbd31fd5a0371b7ffe9ffa2
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial-AT1|PND01-03-samps / Age Group, Lineage, Cell class and subclass

SEC14L3 APBB1 SCEL DENND3

1.18e-04165684b9b6b7b8cd65ba6948a5dd8b715cc7092e0be637
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

ANKRD36B ANKRD17 PRKCA ANKRD36

1.24e-04167684ced6ed9b412739c6ced622523347c10295edbf53
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 PDE7A WNT7A DENND3

1.42e-0417368445808cf69122c16b9d2b5ffa06d15392c55954b7
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 PDE7A WNT7A DENND3

1.42e-041736847fa9dbcb258c3ab974490063951620e2def03db1
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 ATP8B4 PRKCA DYRK4

1.45e-04174684b2fc2a756f8e373ad903bd416d9de703d945fa1c
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 ATP8B4 TESMIN DYRK4

1.45e-04174684a9f34d1237f335d27c5560ff514368f4709f9144
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-Double_negative_thymocyte,_DN3_(Cd8-,_Cd4-),_some_express_pre_TCR_alpha|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 ATP8B4 PRKCA DYRK4

1.45e-041746840fccd90ef72ec2e5eb369fe6d6d126c60886485a
ToppCellP03-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEC14L3 PDE7A APBB1 DENND3

1.52e-04176684f3a54038cde58326f1caed96ecca33c141bcc8b3
ToppCelldroplet-Thymus-nan-21m-Lymphocytic-DN3_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RAB38 ATP8B4 TESMIN DYRK4

1.52e-04176684d43d9e86c4d4fa1e88fbf2b899ac7143717aac90
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE7A TRPM3 SCEL DENND3

1.62e-0417968404ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellCOPD-Myeloid-Mast|World / Disease state, Lineage and Cell class

FMNL3 ATP8B4 TRIM63 PRKCA

1.72e-0418268468a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE7A ANKRD36 MEI1 DENND3

1.72e-04182684a00abff41c12b71d5860c494b8c722d649fd5f36
ToppCell5'-Adult-SmallIntestine-Hematopoietic-Plasma_cells-IgA_plasma_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PDE7A ANKRD36 MEI1 DENND3

1.72e-04182684626aabfd9ac662c1d189f7c4b660482914d9e669
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 PRKCA ASB4 SNRPN

1.76e-04183684b5ede5a0048c585b73c00e88aeddbcaf669347b1
ToppCellRSV-Healthy-5|Healthy / Virus stimulation, Condition and Cluster

MB21D2 DDX60 PARP9 SEPTIN10

1.80e-041846841e282d619ef8035437fabe0fd2aefda1c142f7f6
ToppCellRSV-Healthy-5|RSV / Virus stimulation, Condition and Cluster

MB21D2 DDX60 PARP9 SEPTIN10

1.80e-04184684ba958f731de6c9eff60103d483e020e2c0c7af7c
ToppCellcontrol-Myeloid-pDC|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

FMNL3 KCTD19 APP SNRPN

1.87e-04186684fccee4cfcc887358cf916d974f29627095b5ad9c
ToppCellCOPD-Myeloid-Mast|COPD / Disease state, Lineage and Cell class

FMNL3 ATP8B4 TRIM63 PRKCA

1.87e-04186684def6f0f284acc2154738574c8c5d3d2a5ef1f208
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PDE7A TRPM3 SCEL DENND3

1.87e-041866843aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCellfacs-Trachea-nan-3m-Epithelial-basal_epithelial_cell_of_tracheobronchial_tree|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC14L3 PDE7A PTPRZ1 SCEL

1.91e-04187684fe9fc21192ede2eea61f419d20ccda254569d0a6
ToppCellP28-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEC14L3 WNT7A APBB1 SCEL

1.91e-04187684a4b41904ba05eb76212c949fc3ac197f906c8351
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAB38 PDE7A PTPRZ1 SCEL

2.03e-0419068447e07ea22733306d8885ee9e5f0b033e2f5e2afb
ToppCellfacs-Lung-18m-Epithelial-airway_epithelial-respiratory_basal_cell-basal_epithelial_cell_of_bronchioalveolar_tree|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RAB38 PDE7A PTPRZ1 SCEL

2.03e-04190684261b8afddfdcba4f70b50df126cef7ad00a0aae0
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Fezf2-Excitatory_Neuron.Slc17a7-Slc17a6.Fezf2-Htr2c_(Layer_5,_Retrosplenial_cortex_(RSG)_and_Subiculum,_Tshz2+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

RAB38 TEKT3 CCDC180

2.06e-0475683f225f053d899db133d50e878e8ec04f2a149b93c
ToppCellP07-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEC14L3 WNT7A APBB1 SCEL

2.07e-041916840f360766490bef3495c42f6421b22a988cfc68fb
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SEC14L3 PDE7A WNT7A APBB1

2.11e-04192684be5e246b2350398b985767b2fbede17a8dd8cc44
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)-Exc_L4_RORB_BHLHE22|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

MB21D2 TRPM3 PTPRZ1 CCDC136

2.11e-0419268425460ca9ebd3d49f666394cf99ab77a5e8f77250
ToppCellCOVID-19_Moderate-CD4+_T_activated|COVID-19_Moderate / disease group, cell group and cell class

MB21D2 DDX60 PRKCA PARP9

2.11e-041926847a81652406332afd03a9b3b529e9b5e6c0b54c28
ToppCellCOVID-19_Moderate-CD4+_T_activated|World / disease group, cell group and cell class

MB21D2 DDX60 PRKCA PARP9

2.16e-04193684c2a2a2c14a7085690262db5c2a70e38db67dee18
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B ZNHIT6 ANKRD36 ANKRD36C

2.16e-04193684463274f394757fb2570ae885d58e1f9fa7e60c4a
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PDE7A APBB1 PRKCA SNRPN

2.20e-041946842e2019a7bf57f257f0ff9b24eacff59dbb952ebb
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE7A APBB1 PRKCA SNRPN

2.20e-04194684e0ccf18edbae09fc1068f1e923f1bc0d0ff44195
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PDE7A APBB1 PRKCA SNRPN

2.20e-04194684fc0504730ae576ff46ba0bc9f585c53ab78d914c
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

PDE7A APBB1 PRKCA SNRPN

2.20e-04194684d788d5bd1e651706e7e2d54ada546a5e84f86ff0
ToppCellControl-Lymphoid_T/NK-CD4+_T_naive|Control / Disease group, lineage and cell class

PDE7A APBB1 PRKCA SNRPN

2.20e-04194684aabcd9f71d8ef54add5c46d8a3e226e3ae3ab124
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ANKRD36B ZNHIT6 ANKRD36 ANKRD36C

2.24e-041956843f8ed20ad17afe1545e574e5ca5fe33c3704c7f3
ToppCellEpithelial_cells-AT1_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

MB21D2 WNT7A SCEL DENND3

2.29e-041966846c99d29162848161c1f166a032320f87a5d5a631
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 PDE7A SCEL DENND3

2.33e-04197684bbb7c106d5b96b8e95aeb3e5c293e104fceea234
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_Naive_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

APBB1 PRKCA ANKRD36 ANKRD36C

2.33e-04197684836dd8110d5689f944ad1d301def38c32278b5b5
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SEC14L3 PDE7A SCEL DENND3

2.33e-04197684b0fb5774525ba05f60c635d42f14bb8d79bff17c
ToppCellcontrol-CD8+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE7A APBB1 PRKCA SNRPN

2.38e-04198684a2c70840c38e9a76543060c112e7d9332dd58a89
ToppCellcontrol-CD4+_T_naive|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE7A APBB1 PRKCA SNRPN

2.38e-041986848694e6d02ad73ccf6d48063d6ab61188da02cdc0
ToppCell(11)_FOXN4+-(2)_GFP_FOXI1|(11)_FOXN4+ / shred by cell type by condition

MAP4K5 XIAP PARP9 TRIP11

2.38e-0419868476d40b8c2f8399725b3a62ee2ae0896559cf91eb
ToppCell10x_3'_v2v3-Neoplastic-Differentiated-like-AC-like-AC-like-F|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TRPM3 PTPRZ1 WNT7A APP

2.38e-0419868481c4c5377d0901ee9594424f08b0e4101686c850
ToppCell(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

DDX60 WNT7A SCEL DENND3

2.42e-041996845a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCellcontrol-unassigned|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MAP4K5 WNT7A CCDC180 FMNL2

2.42e-0419968450e2da35edff1aadef939cfbd4549f73c1a07717
ToppCellcontrol-unassigned|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

MAP4K5 WNT7A CCDC180 FMNL2

2.42e-041996845db7c8089172ac8e796613b3cef618d87007a0ab
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

ANKRD36B DDX60 PARP9 ANKRD36C

2.42e-04199684952fac67588ad5676f5939e3c7f8bac803c27064
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

MAP4K5 XIAP PARP9 TRIP11

2.42e-04199684d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

MAP4K5 XIAP PARP9 TRIP11

2.42e-0419968453ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCell(09)_Interm._secr.>cil.-(2)_GFP_FOXI1|(09)_Interm._secr.>cil. / shred by cell type by condition

MAP4K5 XIAP PARP9 TRIP11

2.42e-04199684fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCellcontrol-CD8+_T_naive|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE7A APBB1 PRKCA SNRPN

2.42e-041996846a61ce7404c65e506091fee99a2001f5a9b39f31
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-Treg|Bac-SEP / Disease, condition lineage and cell class

MB21D2 APBB1 ANKRD36 SNRPN

2.42e-04199684e0b6136e28b813299b7ffbe37f1cf830e60cd7d8
ToppCellcontrol-CD4+_T_naive|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

PDE7A APBB1 PRKCA SNRPN

2.47e-042006840adb8dc3188c07a4871c6d524aab8f45dff0b14e
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_naive|Control / Disease, condition lineage and cell class

PDE7A APBB1 PRKCA SNRPN

2.47e-0420068459b446cd886767f19553aed779ab313685789f6f
Diseasepercent glycated albumin

MAP4K5 PRKCA

1.39e-053642EFO_0009304
Diseasetauopathy (implicated_via_orthology)

SNRPB SNRPN

2.06e-0410642DOID:680 (implicated_via_orthology)
Diseasetumor necrosis factor measurement

C6orf89 APBB1

4.77e-0415642EFO_0010834
Diseasedilated cardiomyopathy

FMNL3 PRKCA

8.58e-0420642EFO_0000407
DiseaseSplenomegaly

XIAP APP

1.04e-0322642C0038002
Diseasehypertrophic cardiomyopathy

FMNL3 PRKCA CCDC136

1.06e-0392643EFO_0000538
DiseaseFanconi Anemia

FANCB ERCC1

1.35e-0325642C0015625
Diseasewhite matter integrity, age at assessment

WNT7A PRDM5

1.46e-0326642EFO_0004641, EFO_0008007
Diseaseresponse to tenofovir, creatinine clearance measurement

FMNL3 TRPM3 SNRPN

1.87e-03112643EFO_0007934, EFO_0009279
Diseaselow density lipoprotein cholesterol measurement, C-reactive protein measurement

C6orf89 MAP4K5

2.63e-0335642EFO_0004458, EFO_0004611
Diseasealcohol use disorder measurement, longitudinal alcohol consumption measurement

C6orf89 MAP4K5

2.94e-0337642EFO_0007645, EFO_0009458
Diseasephosphatidylcholine 32:1 measurement

GVINP1 MAP4K5

3.10e-0338642EFO_0010373
Diseaselung non-small cell carcinoma (is_implicated_in)

ERCC1 XPO5 KDM2A

3.46e-03139643DOID:3908 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
DKCKFLHQERMDVCE

APP

131

P05067
EKLDLLTSKCAHLCM

AFTPH

356

Q6ULP2
LHVACEMANVDCVKI

ASB4

111

Q9Y574
VSKIEKMLSEHLCGC

GVINP1

2271

Q7Z2Y8
IQIVCDILNCVMKKH

CEP44

106

Q9C0F1
MKAVHCQEEACAIIL

ANKRD18B

106

A2A2Z9
CVMHVNLEIENVCKK

DDIT4L

106

Q96D03
DKLTQMLKCHVFRCE

APBB1

471

O00213
IDQHEMKCKDCVHLL

ANKRD36

1356

A6QL64
ILLIDQHEMKCKDCV

ANKRD36B

791

Q8N2N9
QHEMKCKDCVHLLKI

ANKRD36B

796

Q8N2N9
VKNDLLELACMCKTV

ATP8B4

771

Q8TF62
LKKCHLCMESIVQAK

ANKRD17

1431

O75179
ECLMHVQNCKKQLLD

CCDC180

451

Q9P1Z9
LVMEHLDKNECVCKL

DENND3

711

A2RUS2
MKAVHCQEEACAIIL

ANKRD19P

106

Q9H560
RCLVKHILANECDLM

RAB38

171

P57729
LKHAMKECLEKCIEQ

PARP9

406

Q8IXQ6
QKCHCFLADIIMDSI

KCTD19

821

Q17RG1
IHEIFDCQECMKKFI

PRDM5

316

Q9NQX1
CCDNDMERKKVLDDL

LTN1

691

O94822
ILLIDQHEMKCKDCV

ANKRD36C

1216

Q5JPF3
QHEMKCKDCVHLLKI

ANKRD36C

1221

Q5JPF3
LIDDLQHCLVNKMCP

MB21D2

361

Q8IYB1
TLQEMEDLCKLHCLT

DDX60

301

Q8IY21
ALKELAKMCILADCT

ERCC1

181

P07992
CLHQDVMKLACDDIR

OR51E1

181

Q8TCB6
HLVLQMALKCADICN

PDE7A

351

Q13946
QLLKKISDLCEMHID

DNAH8

706

Q96JB1
MACEALKHPKCLLES

NLRP5

856

P59047
LMAEEHKCLSNEEKL

PTPRZ1

2151

P23471
LICDVALGKCMDLHE

PARP4

501

Q9UKK3
KEICSRLVCKEHEAM

MFAP5

121

Q13361
RLVCKEHEAMKDELC

MFAP5

126

Q13361
IRCLLDECHKELCNM

MEI1

131

Q5TIA1
TIKEENSHLKIMCCN

FANCB

66

Q8NB91
KCLQMLSVEKIIHCD

DYRK4

216

Q9NR20
NLLSCKMLLHCKRDE

EXOC4

96

Q96A65
EKKLMECCICNEIVH

KDM2A

636

Q9Y2K7
EKLCKICMDRHIAVV

BIRC8

186

Q96P09
DHCNVDEKEIQKCKM

DEFB129

36

Q9H1M3
KDDVHVCILCLRAIM

FMNL3

221

Q8IVF7
CLLCSVHAMEEVVKE

FAM25E

106

A8MYX2
CIKEELMHGECVKEE

ZNHIT6

171

Q9NWK9
SKKDDVHVCIMCLRA

FMNL2

216

Q96PY5
VHELEAAKCLKEDML

CCDC158

151

Q5M9N0
CEELIDLKMIQCKRV

DUS2

41

Q9NX74
CTGCAQKHLKVMLLE

C6orf89

156

Q6UWU4
LKTKMRDCERILHEC

SEC14L3

121

Q9UDX4
HMMKLIEEHCICDCI

LINC00597

16

Q9H2U6
LIQQEIFMVKECKHC

MAP4K5

61

Q9Y4K4
EKEHCSKCLAEQMIL

TESMIN

471

Q9Y4I5
KHMNLILCDCDEFRK

SNRPN

36

P63162
KCDTCDMNVHKQCVI

PRKCA

131

P17252
MVLSKCPEDVELCHK

NARS2

286

Q96I59
KHMNLILCDCDEFRK

SNRPB

36

P14678
ILCCQERMKLHLDKA

TEKT3

226

Q9BXF9
HDKCKLPTVEECMQL

WDR17

1071

Q8IZU2
RSLEDCVECKMHIVE

ARHGAP35

81

Q9NRY4
HGMKNKCQELCCELE

CCDC136

311

Q96JN2
CETLKHPMCKIEELI

NLRP9

706

Q7RTR0
MCKEHEDEKINIYCL

TRIM63

121

Q969Q1
MCFKHQEALKLFCEV

TRIM52

226

Q96A61
EEKLCKICMDRNIAI

XIAP

446

P98170
ALVACKLCKAMAHEA

TRPM3

691

Q9HCF6
EDLKQMCHKADVELL

TRIM51

231

Q9BSJ1
ETKMILDELQICCHS

SCEL

631

O95171
LTDLGKCLMKHEDVC

XPO5

1011

Q9HAV4
KCLMKHEDVCTALLI

XPO5

1016

Q9HAV4
VCDHCKGKMQLVADL

TLNRD1

36

Q9H1K6
NHCDFVKLREMLICT

SEPTIN10

291

Q9P0V9
IMEECENLKLECSKL

TRIP11

346

Q15643
LEIMRICKNHSLDCL

ZNF790

101

Q6PG37
ILEENMKLECKCHGV

WNT7A

191

O00755
DILCAAEMKDKLIDC

ERVK-19

201

Q9WJR5