Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone demethylase activity	JARID2 KDM4C KDM5C KDM4B	9.23e-06	31	86	4	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	JARID2 KDM4C KDM5C KDM4B	1.05e-05	32	86	4	GO:0140457
GeneOntologyMolecularFunction	demethylase activity	JARID2 KDM4C KDM5C KDM4B	3.82e-05	44	86	4	GO:0032451
GeneOntologyMolecularFunction	2-oxoglutarate-dependent dioxygenase activity	TET2 KDM4C KDM5C KDM4B	1.78e-04	65	86	4	GO:0016706
GeneOntologyMolecularFunction	histone H3 demethylase activity	KDM4C KDM5C KDM4B	2.34e-04	28	86	3	GO:0141052
GeneOntologyMolecularFunction	histone H3K9me2/H3K9me3 demethylase activity	KDM4C KDM4B	2.72e-04	6	86	2	GO:0140684
GeneOntologyMolecularFunction	dioxygenase activity	TET2 KDM4C KDM5C KDM4B	8.51e-04	98	86	4	GO:0051213
GeneOntologyBiologicalProcess	monocyte activation involved in immune response	DYSF FER1L5	1.76e-05	2	87	2	GO:0002280
Domain	JmjN	JARID2 KDM4C KDM5C KDM4B	8.22e-08	10	85	4	SM00545
Domain	JmjN	JARID2 KDM4C KDM5C KDM4B	8.22e-08	10	85	4	PF02375
Domain	JMJN	JARID2 KDM4C KDM5C KDM4B	8.22e-08	10	85	4	PS51183
Domain	JmjN	JARID2 KDM4C KDM5C KDM4B	8.22e-08	10	85	4	IPR003349
Domain	JmjC	JARID2 KDM4C KDM5C KDM4B	3.96e-06	24	85	4	PF02373
Domain	JMJC	JARID2 KDM4C KDM5C KDM4B	1.30e-05	32	85	4	PS51184
Domain	JmjC_dom	JARID2 KDM4C KDM5C KDM4B	1.30e-05	32	85	4	IPR003347
Domain	JmjC	JARID2 KDM4C KDM5C KDM4B	1.48e-05	33	85	4	SM00558
Domain	FerA	DYSF FER1L5	6.12e-05	3	85	2	SM01200
Domain	Ferlin_A-domain	DYSF FER1L5	6.12e-05	3	85	2	IPR012560
Domain	FerA	DYSF FER1L5	6.12e-05	3	85	2	PF08165
Domain	DysFC	DYSF FER1L5	1.22e-04	4	85	2	SM00694
Domain	DysFN	DYSF FER1L5	1.22e-04	4	85	2	SM00693
Domain	Peroxin/Ferlin	DYSF FER1L5	1.22e-04	4	85	2	IPR006614
Domain	FerI	DYSF FER1L5	2.03e-04	5	85	2	SM01202
Domain	FerB	DYSF FER1L5	2.03e-04	5	85	2	SM01201
Domain	Ferlin_B-domain	DYSF FER1L5	2.03e-04	5	85	2	IPR012561
Domain	Ferlin_C	DYSF FER1L5	2.03e-04	5	85	2	PF16165
Domain	Ferlin_C	DYSF FER1L5	2.03e-04	5	85	2	IPR032362
Domain	FerIin_dom	DYSF FER1L5	2.03e-04	5	85	2	IPR012968
Domain	FerI	DYSF FER1L5	2.03e-04	5	85	2	PF08151
Domain	FerB	DYSF FER1L5	2.03e-04	5	85	2	PF08150
Domain	zf-C5HC2	JARID2 KDM5C	2.03e-04	5	85	2	PF02928
Domain	Znf_C5HC2	JARID2 KDM5C	2.03e-04	5	85	2	IPR004198
Domain	-	JARID2 KDM5C	2.07e-03	15	85	2	1.10.150.60
Domain	BRIGHT	JARID2 KDM5C	2.07e-03	15	85	2	SM00501
Domain	ARID_dom	JARID2 KDM5C	2.07e-03	15	85	2	IPR001606
Domain	ARID	JARID2 KDM5C	2.07e-03	15	85	2	PS51011
Domain	ARID	JARID2 KDM5C	2.07e-03	15	85	2	PF01388
Domain	EPHD	KDM4C KDM4B	4.46e-03	22	85	2	PS51805
Domain	BRCT	LIG3 CTDP1	4.46e-03	22	85	2	SM00292
Domain	TUDOR	KDM4C KDM4B	4.87e-03	23	85	2	PS50304
Domain	-	LIG3 CTDP1	4.87e-03	23	85	2	3.40.50.10190
Pubmed	Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.	KDM4C KDM5C KDM4B	5.63e-07	7	89	3	28262558
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	MBTD1 CACNB2 ANK3 UBAP2L TLR4 FRMPD1 ETS1 MASTL DDI2 PRKCZ EPDR1 ANKRD50 DNA2 NFAT5	6.52e-07	1084	89	14	11544199
Pubmed	Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.	KDM4C RBBP5 KDM5C KDM4B	5.03e-06	44	89	4	24183668
Pubmed	Jumonji domain-containing protein 2B silencing induces DNA damage response via STAT3 pathway in colorectal cancer.	STAT3 KDM4B	6.48e-06	2	89	2	24473398
Pubmed	Linking the KIR phenotype with STAT3 and TET2 mutations to identify chronic lymphoproliferative disorders of NK cells.	TET2 STAT3	6.48e-06	2	89	2	33512451
Pubmed	Protein kinase C zeta regulates human pancreatic cancer cell transformed growth and invasion through a STAT3-dependent mechanism.	PRKCZ STAT3	6.48e-06	2	89	2	24015205
Pubmed	Downregulation of N-myc Interactor Promotes Cervical Cancer Cells Growth by Activating Stat3 Signaling.	MYCN STAT3	6.48e-06	2	89	2	33106998
Pubmed	KDM4B Overexpression Promotes the Growth, Migration, and Invasion of Rheumatoid Arthritis Fibroblast-Like Synoviocytes by Activating STAT3 Pathway.	STAT3 KDM4B	6.48e-06	2	89	2	33909202
Pubmed	Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity.	KDM4C KDM4B	6.48e-06	2	89	2	24361252
Pubmed	M2-polarized tumor-associated macrophages facilitated migration and epithelial-mesenchymal transition of HCC cells via the TLR4/STAT3 signaling pathway.	TLR4 STAT3	6.48e-06	2	89	2	29338742
Pubmed	Expression of Stat3 in germ cells of developing and adult mouse ovaries and testes.	DDX4 STAT3	6.48e-06	2	89	2	15749075
Pubmed	Understanding the participation of GREM1 polymorphisms in nonsyndromic cleft lip with or without cleft palate in the Brazilian population.	NTN1 GREM1	6.48e-06	2	89	2	30402937
Pubmed	Gremlin-1 activates Akt/STAT3 signaling, which increases the glycolysis rate in breast cancer cells.	GREM1 STAT3	6.48e-06	2	89	2	33097188
Pubmed	Identification of a novel Stat3 recruitment and activation motif within the granulocyte colony-stimulating factor receptor.	CSF3R STAT3	6.48e-06	2	89	2	9864141
Pubmed	Chimeric G-CSF Receptor-Mediated STAT3 Activation Contributes to Efficient Induction of Cardiomyocytes from Mouse Induced Pluripotent Stem Cells.	CSF3R STAT3	6.48e-06	2	89	2	31469473
Pubmed	TLR4 inhibits mesenchymal stem cell (MSC) STAT3 activation and thereby exerts deleterious effects on MSC-mediated cardioprotection.	TLR4 STAT3	6.48e-06	2	89	2	21151968
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	LIG3 DENND4A RBBP5 DOCK10 GON4L AKAP13 ANKRD50 DNA2 PRRC2B SORL1	6.55e-06	650	89	10	38777146
Pubmed	Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.	CACNB2 RAB28 KDM4C MYO3B TLR4 SAMD13 ETS1 NIPBL GALNT13 CDKAL1 TTLL7	7.50e-06	814	89	11	23251661
Pubmed	Identification of Jmjd3 as an Essential Epigenetic Regulator of Hox Gene Temporal Collinear Activation for Body Axial Patterning in Mice.	JARID2 KDM4C KDM5C KDM4B	7.77e-06	49	89	4	34368113
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	UBAP2L SV2B RHOBTB2 FRMPD1 DOCK10 GON4L NFAT5 PRRC2B	1.01e-05	407	89	8	12693553
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	MYCN LIG3 MBTD1 RBBP5 KDM5C FRMPD1 ETS1 ECPAS STAT3 TTLL7 SORL1	1.21e-05	857	89	11	25609649
Pubmed	MiR-193b-3p Regulates TLR4 Expression to Inhibit Inflammation by Targeting ETS1 in Allergic Rhinitis.	TLR4 ETS1	1.94e-05	3	89	2	37231959
Pubmed	Brx mediates the response of lymphocytes to osmotic stress through the activation of NFAT5.	AKAP13 NFAT5	1.94e-05	3	89	2	19211510
Pubmed	Concurrent STAT3, DNMT3A, and TET2 mutations in T-LGL leukemia with molecularly distinct clonal hematopoiesis of indeterminate potential.	TET2 STAT3	1.94e-05	3	89	2	27761930
Pubmed	Non-toxic sulfur inhibits LPS-induced inflammation by regulating TLR-4 and JAK2/STAT3 through IL-6 signaling.	TLR4 STAT3	1.94e-05	3	89	2	33907855
Pubmed	Activation of Stat3 in endothelial cells following hypoxia-reoxygenation is mediated by Rac1 and protein Kinase C.	PRKCZ STAT3	1.94e-05	3	89	2	22791907
Pubmed	Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development.	TET2 DDX4	1.94e-05	3	89	2	23352810
Pubmed	Comparative integromics on JMJD2A, JMJD2B and JMJD2C: preferential expression of JMJD2C in undifferentiated ES cells.	KDM4C KDM4B	1.94e-05	3	89	2	17611647
Pubmed	Clinicopathologic significance of MYD88 L265P mutation and expression of TLR4 and P-STAT3 in primary central nervous system diffuse large B-cell lymphomas.	TLR4 STAT3	1.94e-05	3	89	2	33079297
Pubmed	Proximal tubule-specific overexpression of netrin-1 suppresses acute kidney injury-induced interstitial fibrosis and glomerulosclerosis through suppression of IL-6/STAT3 signaling.	NTN1 STAT3	1.94e-05	3	89	2	23408169
Pubmed	Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development.	TET2 DDX4	1.94e-05	3	89	2	21816367
Pubmed	IL-6 induction of TLR-4 gene expression via STAT3 has an effect on insulin resistance in human skeletal muscle.	TLR4 STAT3	1.94e-05	3	89	2	21293887
Pubmed	TLR4 mediates MAPK-STAT3 axis activation in bladder epithelial cells.	TLR4 STAT3	1.94e-05	3	89	2	23612802
Pubmed	Continual removal of H3K9 promoter methylation by Jmjd2 demethylases is vital for ESC self-renewal and early development.	KDM4C KDM4B	1.94e-05	3	89	2	27266524
Pubmed	The histone demethylase JMJD2C is stage-specifically expressed in preimplantation mouse embryos and is required for embryonic development.	KDM4C KDM4B	1.94e-05	3	89	2	19696013
Pubmed	KDM4B promotes DNA damage response via STAT3 signaling and is a target of CREB in colorectal cancer cells.	STAT3 KDM4B	1.94e-05	3	89	2	29633065
Pubmed	Inhibition of ferroptosis rescues M2 macrophages and alleviates arthritis by suppressing the HMGB1/TLR4/STAT3 axis in M1 macrophages.	TLR4 STAT3	1.94e-05	3	89	2	39029270
Pubmed	Angiotensin II-induced TLR4 mediated abdominal aortic aneurysm in apolipoprotein E knockout mice is dependent on STAT3.	TLR4 STAT3	1.94e-05	3	89	2	26299839
Pubmed	STAT-3 activation is required for normal G-CSF-dependent proliferation and granulocytic differentiation.	CSF3R STAT3	1.94e-05	3	89	2	11239451
Pubmed	The KDM4/JMJD2 histone demethylases are required for hematopoietic stem cell maintenance.	KDM4C KDM4B	1.94e-05	3	89	2	31434704
Pubmed	Histone demethylase JMJD2B and JMJD2C induce fibroblast growth factor 2: mediated tumorigenesis of osteosarcoma.	KDM4C KDM4B	1.94e-05	3	89	2	25636512
Pubmed	GREM1 knockdown regulates the proliferation, apoptosis and EMT of benign prostatic hyperplasia by suppressing the STAT3/c-Myc signaling.	GREM1 STAT3	1.94e-05	3	89	2	37931534
Pubmed	Broad histone H3K4me3 domains in mouse oocytes modulate maternal-to-zygotic transition.	KDM4C KDM5C KDM4B	2.08e-05	21	89	3	27626377
Pubmed	Zfp296 negatively regulates H3K9 methylation in embryonic development as a component of heterochromatin.	KDM4C DDX4 KDM4B	2.41e-05	22	89	3	28963472
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	CACNB2 RAB28 ANK3 UBAP2L FRMPD1 SAMD13 AKAP13 NTN1 PRKCZ ECPAS CATSPERG NFAT5 TSEN2 KDM4B	2.47e-05	1489	89	14	28611215
Pubmed	Molecular reclassification of Crohn's disease by cluster analysis of genetic variants.	TLR4 CDKAL1 STAT3	2.76e-05	23	89	3	20886065
Pubmed	HO-1-STAT3 axis in mouse liver ischemia/reperfusion injury: regulation of TLR4 innate responses through PI3K/PTEN signaling.	TLR4 STAT3	3.87e-05	4	89	2	21756853
Pubmed	G-CSF receptor truncations found in SCN/AML relieve SOCS3-controlled inhibition of STAT5 but leave suppression of STAT3 intact.	CSF3R STAT3	3.87e-05	4	89	2	15069015
Pubmed	The signal transducers Stat1 and Stat3 and their novel target Jmjd3 drive the expression of inflammatory genes in microglia.	TLR4 STAT3	3.87e-05	4	89	2	24097101
Pubmed	Fcp1 phosphatase controls Greatwall kinase to promote PP2A-B55 activation and mitotic progression.	CTDP1 MASTL	3.87e-05	4	89	2	26653855
Pubmed	Jmjd2/Kdm4 demethylases are required for expression of Il3ra and survival of acute myeloid leukemia cells.	KDM4C KDM4B	3.87e-05	4	89	2	27257215
Pubmed	Interleukin-11 reduces TLR4-induced colitis in TLR2-deficient mice and restores intestinal STAT3 signaling.	TLR4 STAT3	3.87e-05	4	89	2	20600022
Pubmed	Tumor-Derived Small Extracellular Vesicles Induce Pro-Inflammatory Cytokine Expression and PD-L1 Regulation in M0 Macrophages via IL-6/STAT3 and TLR4 Signaling Pathways.	TLR4 STAT3	3.87e-05	4	89	2	34829995
Pubmed	The histone demethylase Kdm4 suppresses activation of hepatic stellate cell by inducing MiR-29 transcription.	KDM4C KDM4B	3.87e-05	4	89	2	31014673
Pubmed	TLR9 signaling in the tumor microenvironment initiates cancer recurrence after radiotherapy.	TLR4 STAT3	3.87e-05	4	89	2	24154870
Pubmed	STAT3 restrains RANK- and TLR4-mediated signalling by suppressing expression of the E2 ubiquitin-conjugating enzyme Ubc13.	TLR4 STAT3	3.87e-05	4	89	2	25503582
Pubmed	Regulation of Jumonji-domain-containing histone demethylases by hypoxia-inducible factor (HIF)-1alpha.	KDM4C KDM4B	3.87e-05	4	89	2	18713068
Pubmed	Genetic risk profiling and prediction of disease course in Crohn's disease patients.	TLR4 CDKAL1 STAT3	5.07e-05	28	89	3	19422935
Pubmed	The Epigenetic Factor Landscape of Developing Neocortex Is Regulated by Transcription Factors Pax6→ Tbr2→ Tbr1.	JARID2 MBTD1 KDM4C KDM5C KDM4B	5.38e-05	157	89	5	30186101
Pubmed	Interruption of macrophage-derived IL-27(p28) production by IL-10 during sepsis requires STAT3 but not SOCS3.	TLR4 STAT3	6.44e-05	5	89	2	25348624
Pubmed	Clostridium perfringens α-toxin impairs granulocyte colony-stimulating factor receptor-mediated granulocyte production while triggering septic shock.	CSF3R TLR4	6.44e-05	5	89	2	30729183
Pubmed	STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1β expression.	TLR4 STAT3	6.44e-05	5	89	2	32732870
Pubmed	A miRNA181a/NFAT5 axis links impaired T cell tolerance induction with autoimmune type 1 diabetes.	AKAP13 NFAT5	6.44e-05	5	89	2	29298866
Pubmed	Structural and evolutionary basis for the dual substrate selectivity of human KDM4 histone demethylase family.	KDM4C KDM4B	6.44e-05	5	89	2	21914792
Pubmed	Loss of Calponin 2 causes premature ovarian insufficiency in mice.	FSHR DDX4	6.44e-05	5	89	2	38336796
Pubmed	Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis.	TET2 TLR4	6.44e-05	5	89	2	30526882
Pubmed	Tumor suppressor cylindromatosis acts as a negative regulator for Streptococcus pneumoniae-induced NFAT signaling.	TLR4 NFAT5	6.44e-05	5	89	2	18332137
Pubmed	Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells.	KDM4C KDM4B	6.44e-05	5	89	2	16738407
Pubmed	Interleukin-6 (IL-6) trans signaling drives a STAT3-dependent pathway that leads to hyperactive transforming growth factor-β (TGF-β) signaling promoting SMAD3 activation and fibrosis via Gremlin protein.	GREM1 STAT3	6.44e-05	5	89	2	24550394
Pubmed	STAT3-driven upregulation of TLR2 promotes gastric tumorigenesis independent of tumor inflammation.	TLR4 STAT3	6.44e-05	5	89	2	23079657
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	TET2 PDPR MTUS1 KDM5C ANKRD50 ECPAS DNA2 KDM4B	6.52e-05	529	89	8	14621295
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	JARID2 LIG3 NIPBL PRRC2B	8.65e-05	90	89	4	15033168
Pubmed	Bacterial Lipopolysaccharides Suppress Erythroblastic Islands and Erythropoiesis in the Bone Marrow in an Extrinsic and G- CSF-, IL-1-, and TNF-Independent Manner.	CSF3R TLR4	9.65e-05	6	89	2	33123170
Pubmed	Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice.	TLR4 STAT3	9.65e-05	6	89	2	12727921
Pubmed	Genome-wide association study of bipolar I disorder in the Han Chinese population.	CACNB2 ANK3	9.65e-05	6	89	2	20386566
Pubmed	A β(IV)-spectrin/CaMKII signaling complex is essential for membrane excitability in mice.	CACNB2 ANK3	9.65e-05	6	89	2	20877009
Pubmed	Rac1 modulates the formation of primordial follicles by facilitating STAT3-directed Jagged1, GDF9 and BMP15 transcription in mice.	DDX4 STAT3	9.65e-05	6	89	2	27050391
Pubmed	Direct interaction of Gas41 and Myc encoded by amplified genes in nervous system tumours.	MYCN FRMD4A	9.65e-05	6	89	2	22068108
Pubmed	Identification and characterization of JMJD2 family genes in silico.	KDM4C KDM4B	9.65e-05	6	89	2	15138608
Pubmed	TLR4 Signaling via NANOG Cooperates With STAT3 to Activate Twist1 and Promote Formation of Tumor-Initiating Stem-Like Cells in Livers of Mice.	TLR4 STAT3	9.65e-05	6	89	2	26582088
Pubmed	Identification of Astrotactin2 as a Genetic Modifier That Regulates the Global Orientation of Mammalian Hair Follicles.	FZD6 TLR4	9.65e-05	6	89	2	26418459
Pubmed	High levels of Daxx due to low cellular levels of HSP25 in murine cancer cells result in inefficient adenovirus replication.	ETS1 STAT3	9.65e-05	6	89	2	31615977
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	LIG3 ADAMTS9 RBBP5 KIF26B TAS1R3 MYO3B DDI2 AKAP13 ECPAS	1.14e-04	736	89	9	29676528
Pubmed	TIRAP, an adaptor protein for TLR2/4, transduces a signal from RAGE phosphorylated upon ligand binding.	TLR4 PRKCZ	1.35e-04	7	89	2	21829704
Pubmed	Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.	KDM4C KDM4B	1.35e-04	7	89	2	21445275
Pubmed	Relief of tumor hypoxia unleashes the tumoricidal potential of neutrophils.	CSF3R STAT3	1.35e-04	7	89	2	31600172
Pubmed	Molecular genetics of successful smoking cessation: convergent genome-wide association study results.	BNC2 CACNB2 MTUS1 AKAP13	1.35e-04	101	89	4	18519826
Pubmed	Protein kinase C isoforms zeta and iota mediate collagenase expression and cartilage destruction via STAT3- and ERK-dependent c-fos induction.	PRKCZ STAT3	1.79e-04	8	89	2	20463008
Pubmed	EMR-linked GWAS study: investigation of variation landscape of loci for body mass index in children.	COL6A5 GALNT13	1.79e-04	8	89	2	24348519
Pubmed	The importance of basonuclin 2 in adult mice and its relation to basonuclin 1.	BNC2 DDX4	1.79e-04	8	89	2	26923665
Pubmed	A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.	DENND4A ADAMTS9 KIF26B UBR3 UNC80	1.88e-04	205	89	5	12040188
Pubmed	Knockout mice with pituitary malformations help identify human cases of hypopituitarism.	JARID2 MBTD1 PRRC2B	2.13e-04	45	89	3	38822427
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	MYCN JARID2 BNC2 KDM4C KDM5C ETS1 NFAT5 STAT3 KDM4B	2.29e-04	808	89	9	20412781
Pubmed	Activities of N-Myc in the developing limb link control of skeletal size with digit separation.	MYCN GREM1	2.30e-04	9	89	2	17360777
Pubmed	Human transcription factor protein interaction networks.	TET2 LIG3 MBTD1 RBBP5 UBAP2L ETS1 GON4L EPDR1 NIPBL STAT3 PRRC2B SORL1	2.82e-04	1429	89	12	35140242
Pubmed	Predicting type 2 diabetes based on polymorphisms from genome-wide association studies: a population-based study.	ADAMTS9 CDKAL1	2.88e-04	10	89	2	18694974
Pubmed	Postnatal refinement of auditory hair cell planar polarity deficits occurs in the absence of Vangl2.	TUBB1 FZD6	2.88e-04	10	89	2	23986237
Pubmed	Deletion of JMJD2B in neurons leads to defective spine maturation, hyperactive behavior and memory deficits in mouse.	KDM4C KDM4B	2.88e-04	10	89	2	27023172
Pubmed	Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations.	C2orf88 CDKAL1	2.88e-04	10	89	2	22344221
Pubmed	Interaction network of human early embryonic transcription factors.	TET2 LIG3 MBTD1 RBBP5 NIPBL PRRC2B	2.91e-04	351	89	6	38297188
Cytoband	16q22.1	PDPR CES3 NFAT5	1.31e-03	110	89	3	16q22.1
Cytoband	4q24	TET2 GSTCD	2.00e-03	34	89	2	4q24
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM4C KDM5C KDM4B	7.75e-05	24	63	3	485
GeneFamily	Ferlin family	DYSF FER1L5	1.78e-04	6	63	2	828
GeneFamily	AT-rich interaction domain containing	JARID2 KDM5C	1.22e-03	15	63	2	418
GeneFamily	CTAGE family	CTAGE15 CTAGE6	1.22e-03	15	63	2	907
Coexpression	GSE32423_CTRL_VS_IL4_MEMORY_CD8_TCELL_UP	RHOBTB2 MIER3 DOCK10 BBS9 NIPBL RCAN2 DYRK3	5.50e-06	200	89	7	M5085
Coexpression	DAVICIONI_MOLECULAR_ARMS_VS_ERMS_UP	MYCN JARID2 RAB28 KDM4C FRMPD1 GREM1 QDPR PRRC2B	2.09e-05	340	89	8	M2012
Coexpression	OISHI_CHOLANGIOMA_STEM_CELL_LIKE_UP	FRMD4A RAB28 RBBP5 UBAP2L GON4L AASDHPPT FH DYRK3	2.52e-05	349	89	8	M283
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TET2 JARID2 TLR4 DOCK10 MASTL AKAP13	8.38e-07	160	89	6	6ed37d1fd0304932319d6b942502404115ff36a7
ToppCell	P15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FMO2 CLCN7 FAT3 COL6A5 KDM4B SORL1	1.19e-06	170	89	6	ba4ba66b624089ed50a9083176386c7941b4c7a3
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 ETS1 TENM1 DOCK10 AASDHPPT SORL1	1.89e-06	184	89	6	bd786db4dc4edae6d5cfc0b69901983dea19f729
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 ANK3 MTUS1 NTN1 EPDR1	2.01e-06	186	89	6	6add08d4ca019ff2864acdd5ec2c66a59a574591
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIF26B GLRA2 FRMPD1 SAMD13 ETS1 TENM1	2.08e-06	187	89	6	d413fb4b1531b297af5012a392b88128510c2de8
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 CSF3R MTUS1 RHOBTB2 AKAP13 PRKCZ	2.08e-06	187	89	6	5df9e1f5ca32217af255e76e6fb5afa346337811
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 ANK3 FAT3 NTN1 EPDR1	2.14e-06	188	89	6	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 CACNB2 NTN1 GREM1 RCAN2 TTLL7	2.14e-06	188	89	6	879de94924de978478696fc7838e05a4d795b905
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	BNC2 CACNB2 NTN1 GREM1 RCAN2 TTLL7	2.21e-06	189	89	6	ab7ece0a517499b70b7754720d3e434765363af6
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 MTUS1 FAT3 NTN1 EPDR1	2.21e-06	189	89	6	45e588b2a4ad9e3ff74e22d9d627ed3571f3b8b8
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MTUS1 KIF26B FRMPD1 SAMD13 ETS1 TENM1	2.28e-06	190	89	6	305fbef734c350cfbf786ca7ff6e07093aab56ea
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MTUS1 KIF26B MYO3B FRMPD1 ETS1 TENM1	2.28e-06	190	89	6	39ab890104b4264c68a968f920f4ccd84f0bc681
ToppCell	wk_08-11-Epithelial-Proximal_epithelial-GHRL+_neuroendocrine\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	KCNH7 SV2B FRMPD1 TENM1 UNC80 TTLL7	2.28e-06	190	89	6	b5c6f3248c0c2f648e1578457c6a729ca22bf0da
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 ANK3 MTUS1 NTN1 EPDR1	2.35e-06	191	89	6	b133ee1c0e58d00ddd2e4e05b01fd04947524c18
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRMD4A BNC2 CACNB2 KIF26B COL6A5 RCAN2	2.42e-06	192	89	6	df1545670370fb1010c567cd059c2783eab315f7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FZD6 ANK3 MTUS1 RHOBTB2 AKAP13 PRKCZ	2.42e-06	192	89	6	29f49f00770c991b5f27e4cb701dd2d2d6cb7178
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	JARID2 DENND4A KDM4C AKAP13 NFAT5 CDKAL1	2.49e-06	193	89	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D231\|Adult / Lineage, Cell type, age group and donor	BNC2 CACNB2 FMO2 KIF26B FAT3 COL6A5	2.49e-06	193	89	6	ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CSF3R MTUS1 RHOBTB2 AKAP13 PRKCZ EPDR1	2.49e-06	193	89	6	ba484fa1f290a92ae02475a4c468b4ac840c133e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MTUS1 KIF26B GLRA2 FRMPD1 TENM1 DOCK10	2.57e-06	194	89	6	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ANK3 CSF3R MTUS1 RHOBTB2 AKAP13 EPDR1	2.72e-06	196	89	6	7e5addaa844e66f8160e05858c341866a80aed23
ToppCell	cellseq-Epithelial-Epithelial_Alveolar\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CSF3R MTUS1 RHOBTB2 AKAP13 PRKCZ EPDR1	2.72e-06	196	89	6	a7cbe66ebd8931ef2b8ff26a42afce0ad1c48f17
ToppCell	distal-1-Epithelial-Alveolar_Epithelial_Type_1\|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FZD6 FMO2 RHOBTB2 PRKCZ GALNT13 TTLL7	2.81e-06	197	89	6	d44b7dc7c6416ed9466889374c3ae39f43ac8bb6
ToppCell	COVID-19-lung-Fibroblast\|COVID-19 / Disease (COVID-19 only), tissue and cell type	BNC2 CACNB2 FMO2 KIF26B FAT3 COL6A5	2.89e-06	198	89	6	3ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 MTUS1 AKAP13 PRKCZ GALNT13	5.68e-06	127	89	5	5b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	BNC2 ETS1 TENM1 AKAP13 SORL1	1.59e-05	157	89	5	170197b76620df31495f1247f365da382b2d8045
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122\|Adult / Lineage, Cell type, age group and donor	ANK3 CSF3R MTUS1 AKAP13 PRKCZ	1.59e-05	157	89	5	31d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	BNC2 ETS1 TENM1 AKAP13 SORL1	1.59e-05	157	89	5	c21520301cc0d5d4b1cc4b8ec735f9adb698e768
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	BNC2 ETS1 TENM1 AKAP13 SORL1	1.64e-05	158	89	5	7274f020c0ecf216da4b6689c62bc5f49c29b6f3
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPINK4 ANK3 MTUS1 RHOBTB2 EPDR1	1.69e-05	159	89	5	e6ff9d2bce62bf9ea173af80b688eeb40fa4ea4c
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 FSHR COL6A5 UNC80 GALNT13	1.74e-05	160	89	5	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	RV-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNB2 ADAMTS9 FAT3 DOCK10 TTLL7	1.74e-05	160	89	5	29c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 FSHR COL6A5 UNC80 GALNT13	1.74e-05	160	89	5	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Adult / Lineage, Cell type, age group and donor	ANK3 CSF3R MTUS1 AKAP13 PRKCZ	1.91e-05	163	89	5	e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCell	Ionocyte-iono-1\|World / Class top	FRMD4A DENND4A GALNT13 RCAN2 TTLL7	2.27e-05	169	89	5	4b68bcb4b5fc3cd2db23cd4edace7444aa2d605c
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TET2 CSF3R CTDP1 STAT3 SORL1	2.40e-05	171	89	5	2b7c5a557c4bc5c573211c4d618bdd6766a24916
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TET2 CSF3R CTDP1 STAT3 SORL1	2.40e-05	171	89	5	dcb15bc54aeea06ef8f07f1134f3ff1e21ac0e4f
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	CACNB2 FAT3 NTN1 RCAN2 TTLL7	2.54e-05	173	89	5	cb6389536195443633adb06e5f1b7483530773d1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 DOCK10 NTN1 UNC80 RCAN2	2.68e-05	175	89	5	98947a226b5a2ac7091ff9d34243ea7736add973
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TET2 FRMD4A DENND4A FAT3 AKAP13	2.68e-05	175	89	5	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	AASDHPPT NIPBL CDKAL1 PRRC2B	2.94e-05	88	89	4	142d2e00ef19c0ad011a21945bf1111271056eae
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	FRMD4A CACNB2 ADAMTS9 RCAN2 TTLL7	2.99e-05	179	89	5	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	Control-Fibroblasts-Airway_smooth_muscle\|Control / group, cell type (main and fine annotations)	CACNB2 FAT3 NTN1 RCAN2 TTLL7	3.07e-05	180	89	5	d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 CACNB2 FMO2 FAT3 COL6A5	3.15e-05	181	89	5	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	saliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	TET2 CSF3R CTDP1 STAT3 SORL1	3.23e-05	182	89	5	dc32f8f6a3b13918eb8e93c018f5823d86344080
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	CACNB2 ADAMTS9 FAT3 RCAN2 TTLL7	3.32e-05	183	89	5	818fd886e0188091310825f9145fa53328f2c979
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 FAT3 DOCK10 NTN1	3.32e-05	183	89	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MTUS1 KIF26B FRMPD1 ETS1 TENM1	3.32e-05	183	89	5	04d3cc76038b8192c915f1c08c3e26f2ad3b3779
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ADAMTS9 SV2B ETS1 NTN1 DYSF	3.32e-05	183	89	5	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	CACNB2 ADAMTS9 FAT3 RCAN2 TTLL7	3.32e-05	183	89	5	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B FAT3 TENM1 UNC80 GALNT13	3.40e-05	184	89	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B FAT3 TENM1 UNC80 GALNT13	3.40e-05	184	89	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIF26B FAT3 TENM1 UNC80 GALNT13	3.40e-05	184	89	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D122\|Adult / Lineage, Cell type, age group and donor	FZD6 FMO2 PRKCZ GALNT13 TTLL7	3.40e-05	184	89	5	561592edc3083fad41b91811151b442207c65dd9
ToppCell	PBMC-Mild-cDC_9\|Mild / Compartment, Disease Groups and Clusters	KIF26B TLR4 SAMD13 CES3 TTLL7	3.40e-05	184	89	5	2e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TUBB1 MBTD1 SPINK4 C2orf88 TTLL7	3.49e-05	185	89	5	709236097cbfc254796fcc69b5f5178b73dad9bd
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_4\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TUBB1 MBTD1 SPINK4 C2orf88 TTLL7	3.49e-05	185	89	5	af078a6c4a3e0b54b7d8ab7b30dcd06053ebfd28
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 ANK3 DOCK10 NTN1	3.49e-05	185	89	5	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Degenerative_Cortical_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 DOCK10 NTN1 UNC80 RCAN2	3.49e-05	185	89	5	9438097e94219c1db922b8507e3a29106d32a923
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ANK3 MTUS1 RHOBTB2 NTN1 PRKCZ	3.59e-05	186	89	5	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine2[NE2]_(12)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KCNH7 SV2B UNC80 GALNT13 CFAP65	3.59e-05	186	89	5	c7983281a290201567b398e9ea6baddb96c692bb
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 MTUS1 NTN1 NFAT5 RCAN2	3.59e-05	186	89	5	a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	BNC2 CACNB2 KIF26B RCAN2 TTLL7	3.68e-05	187	89	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	LPS-antiTNF-Epithelial_alveolar\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 ANK3 MTUS1 PRKCZ GALNT13	3.68e-05	187	89	5	201ff693e4756ee3e44762885b3a303a77eb535b
ToppCell	3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.1.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MTUS1 RHOBTB2 AKAP13 PRKCZ EPDR1	3.68e-05	187	89	5	7c44cec1c26ca5907a495f2d7e633410e2e9728f
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1\|Adult / Lineage, Cell type, age group and donor	FZD6 FMO2 PRKCZ GALNT13 TTLL7	3.68e-05	187	89	5	77f78aec946bc6bd85c29aee9ca978ce49f853a3
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	ADAMTS9 KIF26B SV2B NTN1 DYSF	3.68e-05	187	89	5	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	CACNB2 FAT3 DOCK10 RCAN2 TTLL7	3.77e-05	188	89	5	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FMO2 ANK3 MTUS1 PRKCZ GALNT13	3.77e-05	188	89	5	43a0508d2524a5b310e89e9422843dcaab999bc3
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 ANK3 MTUS1 NTN1	3.77e-05	188	89	5	293f2fa99f5f96aa7fd2b2a5cc94ff60eeaabe11
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CACNB2 MTUS1 NTN1 NFAT5 RCAN2	3.77e-05	188	89	5	e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 ETS1 TENM1 DOCK10 SORL1	3.87e-05	189	89	5	9ab77c6fcb573854da5922412f53d2168bda6b58
ToppCell	IPF-Epithelial-Aberrant_Basaloid\|Epithelial / Disease state, Lineage and Cell class	MYCN ADAMTS9 MYO3B ETS1 RCAN2	3.87e-05	189	89	5	4178be3292ff4a8a1d8098f638d4b8d15164d2c6
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ANK3 MYO3B NTN1 PRKCZ SORL1	3.87e-05	189	89	5	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIF26B FRMPD1 SAMD13 ETS1 TENM1	3.87e-05	189	89	5	99a13b1b669b0cd36e3096632351d9ade25d1173
ToppCell	IPF-Epithelial-Club\|IPF / Disease state, Lineage and Cell class	FMO2 ANK3 MTUS1 NTN1 PRKCZ	3.87e-05	189	89	5	f3fcef008ef252b29ac6d567fef27f9acf9cd70f
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 KIF26B FAT3 COL6A5	3.87e-05	189	89	5	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ANK3 CSF3R MTUS1 RHOBTB2 PRKCZ	3.97e-05	190	89	5	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FRMD4A BNC2 CACNB2 KIF26B COL6A5	3.97e-05	190	89	5	45df8fee00f8949937863159d7aa042e72748d9b
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MTUS1 KIF26B FRMPD1 ETS1 TENM1	3.97e-05	190	89	5	3f22c118d552345f731d4d49f0bcb5765d93de3b
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIF26B FRMPD1 SAMD13 ETS1 TENM1	3.97e-05	190	89	5	8c9c230a509afaeee50644153974a5642b01a2b8
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_neuroendocrine1[NE1]_(11)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KCNH7 SV2B TENM1 UNC80 CFAP65	3.97e-05	190	89	5	b1095b2a7467c152d16e4f19a9515aeb61fc9e3d
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIF26B MYO3B FRMPD1 ETS1 TENM1	3.97e-05	190	89	5	0acf1d5da68db449d8c9e70519a236ce825f9d11
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L2-4_PVALB_C8orf4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MTUS1 KIF26B FRMPD1 ETS1 TENM1	3.97e-05	190	89	5	e58e4b6fbeb4368f738adac67ec10879c0966f0f
ToppCell	Control-Stromal_mesenchymal\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 FAT3 NTN1 COL6A5	4.07e-05	191	89	5	14057205ddb9b4bbc582d1358d13cf36d979a61b
ToppCell	LA-03._Atrial_Cardiomyocyte\|LA / Chamber and Cluster_Paper	CACNB2 ANK3 NTN1 DYSF RCAN2	4.07e-05	191	89	5	5d1b674eb7703830b7ce8bbeac3363cabd0e6ae9
ToppCell	IPF-Epithelial-Club\|World / Disease state, Lineage and Cell class	FMO2 ANK3 MTUS1 NTN1 PRKCZ	4.07e-05	191	89	5	3c88a6f1d74bb3b9173cd0ea3a63c6d9570e3954
ToppCell	COVID-19-lung-AT2\|lung / Disease (COVID-19 only), tissue and cell type	ANK3 CSF3R MTUS1 RHOBTB2 PRKCZ	4.07e-05	191	89	5	276455a64c2c3503d5048615762eb2ee37f0ac70
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BNC2 CACNB2 FAT3 NTN1 UNC80	4.17e-05	192	89	5	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	DENND4A ANK3 DOCK10 STAT3 SORL1	4.17e-05	192	89	5	47646d7e4990be85072987f92bf18d52f8da752e
ToppCell	LPS_only-Stromal_mesenchymal\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 KIF26B FAT3 COL6A5	4.17e-05	192	89	5	162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L5_PVALB_CNTNAP3P2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIF26B GLRA2 FRMPD1 ETS1 TENM1	4.17e-05	192	89	5	0003d7ef9a8e521e70ac33c63aad843d9b6215c2
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	BNC2 CACNB2 KIF26B FAT3 COL6A5	4.17e-05	192	89	5	deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.0.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CSF3R MTUS1 RHOBTB2 AKAP13 EPDR1	4.27e-05	193	89	5	8646e573f2d2ff175f3d02bfdf214e65f3b614d3
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic-erythrocyte\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TUBB1 FRMD4A DENND4A DDI2 DYRK3	4.27e-05	193	89	5	305e15ee467826ee08b2617c69f250ad39c11b19
ToppCell	5'-Adult-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MTUS1 KIF26B SV2B NTN1 DYSF	4.27e-05	193	89	5	bd0027fa97de41ae22ff64a61c8e217496f122ca
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KIF26B FRMPD1 SAMD13 ETS1 TENM1	4.27e-05	193	89	5	c4b22b62f3cc7bf0ec0eba76e1504c236290bbc9
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BNC2 ETS1 TENM1 DOCK10 SORL1	4.27e-05	193	89	5	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	10x_3'_v3-bone_marrow_(10x_3'_v3)-hematologic-erythrocytic\|bone_marrow_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	TUBB1 FRMD4A DENND4A DDI2 DYRK3	4.27e-05	193	89	5	dd376664906caccc9c2065f8e7a364509e18a5cc
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ANK3 MTUS1 QDPR RCAN2 TTLL7	4.38e-05	194	89	5	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Down 200; 7.2uM; MCF7; HT_HG-U133A	FRMD4A MBTD1 RAB28 SPINK4 KDM4C GSTCD CDKAL1	9.70e-06	192	88	7	3612_DN
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A	KDM4C GSTCD AKAP13 ECPAS BBS9 CDKAL1 SORL1	1.04e-05	194	88	7	4727_DN
Drug	Dubinidine [22964-77-8]; Up 200; 14.6uM; MCF7; HT_HG-U133A	LIG3 SPINK4 CLCN7 ADAMTS9 CTDP1 GSTCD DYRK3	1.15e-05	197	88	7	6250_UP
Drug	Aminocaproic acid [60-32-2]; Down 200; 30.4uM; HL60; HT_HG-U133A	LIG3 RHOBTB2 CTDP1 PRKCZ DYSF BBS9 KDM4B	1.15e-05	197	88	7	3122_DN
Drug	Methoxy-6-harmalan [3589-73-9]; Up 200; 18.6uM; HL60; HG-U133A	LIG3 UBAP2L RHOBTB2 GON4L AKAP13 FH DYRK3	1.18e-05	198	88	7	1743_UP
Drug	Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; MCF7; HT_HG-U133A	LIG3 MBTD1 GPATCH3 CTDP1 CDKAL1 PRRC2B DYRK3	1.18e-05	198	88	7	3466_DN
Drug	SC 19220; Up 200; 10uM; MCF7; HT_HG-U133A	LIG3 CACNB2 MTUS1 KDM4C DYSF CDKAL1 KDM4B	1.22e-05	199	88	7	7090_UP
Drug	AC1L3M3D	CTDP1 HACL1 GREM1 BBS9	2.75e-05	45	88	4	CID000091445
Drug	Oxybutynin chloride [1508-65-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A	CLCN7 BBS9 CDKAL1 KDM4B TTLL7 DYRK3	9.31e-05	189	88	6	6770_UP
Drug	AC1L3XA1	MYCN GSTCD STAT3	9.34e-05	23	88	3	CID000123782
Drug	Meclofenoxate hydrochloride [3685-84-5]; Down 200; 13.6uM; MCF7; HT_HG-U133A	FRMD4A LIG3 MBTD1 NFAT5 BBS9 DYRK3	9.87e-05	191	88	6	3605_DN
Drug	Labetalol hydrochloride [32780-64-6]; Down 200; 11uM; MCF7; HT_HG-U133A	FRMD4A CLCN7 GPATCH3 RHOBTB2 CTDP1 CDKAL1	1.02e-04	192	88	6	6809_DN
Drug	Cimetidine [51481-61-9]; Down 200; 15.8uM; MCF7; HT_HG-U133A	KDM4C CTDP1 AKAP13 NFAT5 CDKAL1 SORL1	1.04e-04	193	88	6	1464_DN
Drug	Betahistine mesylate [54856-23-4]; Down 200; 17.2uM; MCF7; HT_HG-U133A	RAB28 RBBP5 AKAP13 DNA2 NFAT5 BBS9	1.04e-04	193	88	6	2833_DN
Drug	Indomethacin [53-86-1]; Down 200; 11.2uM; PC3; HT_HG-U133A	MBTD1 ANK3 RHOBTB2 ETS1 GON4L FH	1.07e-04	194	88	6	5049_DN
Drug	Cyanocobalamin [68-19-9]; Down 200; 3uM; PC3; HT_HG-U133A	DENND4A MTUS1 KDM4C RHOBTB2 CES3 BBS9	1.07e-04	194	88	6	4572_DN
Drug	PHA-00745360 [351320-33-7]; Down 200; 10uM; PC3; HT_HG-U133A	LIG3 KDM5C RHOBTB2 TENM1 CES3 GON4L	1.07e-04	194	88	6	4559_DN
Drug	Moxalactam disodium salt [64953-12-4]; Down 200; 7uM; PC3; HT_HG-U133A	LIG3 MBTD1 DENND4A MTUS1 RHOBTB2 CTDP1	1.07e-04	194	88	6	4648_DN
Drug	Trioxsalen [3902-71-4]; Down 200; 17.6uM; PC3; HT_HG-U133A	MBTD1 KDM4C UBAP2L RHOBTB2 AKAP13 BBS9	1.11e-04	195	88	6	5736_DN
Drug	radicicol; Up 200; 0.1uM; PC3; HT_HG-U133A	LIG3 CLCN7 MTUS1 DOCK10 GREM1 BBS9	1.11e-04	195	88	6	5952_UP
Drug	oxaprozin; Down 200; 300uM; MCF7; HT_HG-U133A_EA	RAB28 KDM5C DNA2 NFAT5 KDM4B SORL1	1.11e-04	195	88	6	863_DN
Drug	Mevalonic-D, L acid lactone [674-26-0]; Down 200; 30.8uM; MCF7; HT_HG-U133A	MBTD1 KDM5C NFAT5 BBS9 CDKAL1 DYRK3	1.11e-04	195	88	6	3459_DN
Drug	Clomiphene citrate (Z,E) [50-41-9]; Down 200; 6.6uM; PC3; HT_HG-U133A	MBTD1 DENND4A MTUS1 GSTCD TENM1 DOCK10	1.11e-04	195	88	6	6648_DN
Drug	0179445-0000 [211246-22-9]; Down 200; 1uM; MCF7; HT_HG-U133A	FRMD4A MBTD1 CLCN7 GPATCH3 DNA2 BBS9	1.14e-04	196	88	6	3633_DN
Drug	(S)-(-)-Cycloserine [339-72-0]; Down 200; 39.2uM; PC3; HT_HG-U133A	RAB28 CLCN7 KDM4C GSTCD ETS1 CDKAL1	1.14e-04	196	88	6	3789_DN
Drug	amitriptyline hydrochloride; Down 200; 1uM; MCF7; HG-U133A	LIG3 RAB28 CLCN7 MTUS1 QDPR NIPBL	1.14e-04	196	88	6	167_DN
Drug	Tinidazole [19387-91-8]; Down 200; 16.2uM; PC3; HT_HG-U133A	MBTD1 MTUS1 KDM5C TENM1 GREM1 BBS9	1.14e-04	196	88	6	4548_DN
Drug	Hydrastinine hydrochloride [4884-68-8]; Down 200; 16.4uM; PC3; HT_HG-U133A	LIG3 KDM4C CTDP1 GON4L NIPBL PRRC2B	1.14e-04	196	88	6	2119_DN
Drug	Flunarizine dihydrochloride [30484-77-6]; Up 200; 8.4uM; PC3; HT_HG-U133A	MBTD1 DENND4A GON4L AKAP13 NFAT5 KDM4B	1.14e-04	196	88	6	7252_UP
Drug	Cefoperazone dihydrate; Down 200; 5.8uM; PC3; HT_HG-U133A	DENND4A CLCN7 MTUS1 CTDP1 GON4L DYSF	1.14e-04	196	88	6	6323_DN
Drug	Meclofenamic acid sodium salt monohydrate [6385-02-0]; Down 200; 11.8uM; PC3; HT_HG-U133A	ANK3 CLCN7 GPATCH3 KDM4C BBS9 PRRC2B	1.17e-04	197	88	6	2128_DN
Drug	Flucloxacillin sodium [1847-24-1]; Down 200; 8.4uM; MCF7; HT_HG-U133A	SPINK4 CLCN7 MTUS1 KDM5C CDKAL1 DYRK3	1.17e-04	197	88	6	6507_DN
Drug	Fluorometholone [426-13-1]; Down 200; 10.6uM; PC3; HT_HG-U133A	RAB28 ANK3 MTUS1 KDM4C RHOBTB2 BBS9	1.17e-04	197	88	6	5771_DN
Drug	Amidopyrine [58-15-1]; Up 200; 17.2uM; PC3; HT_HG-U133A	LIG3 GPATCH3 MTUS1 KDM4C RHOBTB2 NIPBL	1.20e-04	198	88	6	2060_UP
Drug	Diprophylline [479-18-5]; Up 200; 15.8uM; MCF7; HT_HG-U133A	FRMD4A LIG3 GSTCD AKAP13 BBS9 CDKAL1	1.20e-04	198	88	6	1689_UP
Drug	Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; PC3; HT_HG-U133A	MYCN MBTD1 FRMPD1 CES3 DOCK10 GON4L	1.20e-04	198	88	6	6682_UP
Drug	Canrenoic acid potassium salt [2181-04-6]; Up 200; 10uM; PC3; HT_HG-U133A	LIG3 MBTD1 RAB28 ANK3 KDM4C BBS9	1.20e-04	198	88	6	2065_UP
Drug	Medrysone [2668-66-8]; Down 200; 11.6uM; MCF7; HT_HG-U133A	LIG3 RAB28 KDM4C CTDP1 GSTCD AKAP13	1.20e-04	198	88	6	3603_DN
Drug	Dyclonine hydrochloride [536-43-6]; Up 200; 12.2uM; PC3; HT_HG-U133A	MBTD1 UBAP2L DOCK10 AKAP13 NIPBL KDM4B	1.20e-04	198	88	6	7261_UP
Drug	Nicardipine hydrochloride [54527-84-3]; Down 200; 7.8uM; PC3; HT_HG-U133A	MBTD1 DENND4A KDM4C KDM5C BBS9 PRRC2B	1.20e-04	198	88	6	6297_DN
Drug	Nomifensine maleate [32795-47-4]; Up 200; 11.2uM; PC3; HT_HG-U133A	MBTD1 FRMPD1 ETS1 GON4L CDKAL1 SORL1	1.24e-04	199	88	6	2062_UP
Drug	(-) -Levobunolol hydrochloride [27912-14-7]; Down 200; 12.2uM; PC3; HT_HG-U133A	LIG3 CACNB2 CLCN7 KDM5C BBS9 KDM4B	1.24e-04	199	88	6	4016_DN
Drug	Ethotoin [86-35-1]; Down 200; 19.6uM; PC3; HT_HG-U133A	LIG3 CACNB2 CLCN7 RHOBTB2 KDM4B TTLL7	1.24e-04	199	88	6	3809_DN
Drug	Lysergol [602-85-7]; Down 200; 15.8uM; HL60; HT_HG-U133A	LIG3 MBTD1 GSTCD ECPAS CDKAL1 DYRK3	1.24e-04	199	88	6	1325_DN
Drug	THIP Hydrochloride; Up 200; 22.6uM; MCF7; HT_HG-U133A	CACNB2 KDM5C GSTCD TENM1 CES3 CDKAL1	1.24e-04	199	88	6	6511_UP
Drug	Acenocoumarol [152-72-7]; Up 200; 11.4uM; PC3; HT_HG-U133A	RAB28 CLCN7 MTUS1 AKAP13 GREM1 CDKAL1	1.27e-04	200	88	6	2077_UP
Disease	cortical surface area measurement	TET2 BNC2 ANK3 ADAMTS9 RBBP5 KIF26B FAT3 FSHR ETS1 DOCK10 NTN1 PRKCZ DYSF BBS9 CDKAL1	6.29e-06	1345	85	15	EFO_0010736
Disease	Childhood Medulloblastoma	MYCN KDM4C STAT3 KDM4B	7.26e-06	43	85	4	C0278510
Disease	Melanotic medulloblastoma	MYCN KDM4C STAT3 KDM4B	7.26e-06	43	85	4	C1275668
Disease	Medullomyoblastoma	MYCN KDM4C STAT3 KDM4B	7.26e-06	43	85	4	C0205833
Disease	Desmoplastic Medulloblastoma	MYCN KDM4C STAT3 KDM4B	7.26e-06	43	85	4	C0751291
Disease	Adult Medulloblastoma	MYCN KDM4C STAT3 KDM4B	7.26e-06	43	85	4	C0278876
Disease	pulse pressure measurement	TET2 BNC2 LIG3 CACNB2 PDPR FAT3 UBR3 DDI2 AKAP13 DYSF NFAT5 FER1L5 CDKAL1 STAT3 KDM4B	9.48e-06	1392	85	15	EFO_0005763
Disease	neuroimaging measurement	CACNB2 PDPR ANK3 RBBP5 KIF26B FAT3 TLR4 FSHR NTN1 PRKCZ DYSF BBS9 KDM4B	1.13e-05	1069	85	13	EFO_0004346
Disease	Medulloblastoma	MYCN KDM4C STAT3 KDM4B	1.33e-05	50	85	4	C0025149
Disease	brain measurement, neuroimaging measurement	CACNB2 ANK3 ADAMTS9 RBBP5 KIF26B FAT3 NTN1 PRKCZ BBS9	2.98e-05	550	85	9	EFO_0004346, EFO_0004464
Disease	language measurement	ANK3 DOCK10 GON4L QDPR BBS9	4.39e-05	134	85	5	EFO_0007797
Disease	medulloblastoma (is_marker_for)	KDM4C KDM4B	8.15e-05	5	85	2	DOID:0050902 (is_marker_for)
Disease	chronic myelomonocytic leukemia (is_implicated_in)	TET2 CSF3R	8.15e-05	5	85	2	DOID:0080188 (is_implicated_in)
Disease	monocyte count	TET2 DENND4A CSF3R CTDP1 ETS1 CES3 DOCK10 FCRLB GON4L AKAP13 CDKAL1 KDM4B SORL1	9.97e-05	1320	85	13	EFO_0005091
Disease	frozen shoulder	AKAP13 EPDR1	1.71e-04	7	85	2	EFO_1000941
Disease	neutropenia (implicated_via_orthology)	CSF3R STAT3	1.71e-04	7	85	2	DOID:1227 (implicated_via_orthology)
Disease	limb-girdle muscular dystrophy (implicated_via_orthology)	DYSF FER1L5	1.71e-04	7	85	2	DOID:11724 (implicated_via_orthology)
Disease	osteoarthritis, knee, body mass index	BNC2 NFAT5 CDKAL1	2.27e-04	41	85	3	EFO_0004340, EFO_0004616
Disease	urate measurement	BNC2 MYO3B GON4L AKAP13 DYSF NFAT5 CDKAL1 KDM4B PRRC2B RCAN2	2.51e-04	895	85	10	EFO_0004531
Disease	age at menarche	TET2 KDM4C TLR4 ECPAS NFAT5 UNC80 CDKAL1 KDM4B	3.18e-04	594	85	8	EFO_0004703
Disease	diffuse plaque measurement	FRMD4A CACNB2 RAB28 FMO2 RBBP5 KIF26B MYO3B MIER3 CDKAL1	3.36e-04	758	85	9	EFO_0010699
Disease	alopecia areata (is_marker_for)	KDM4C KDM4B	3.64e-04	10	85	2	DOID:986 (is_marker_for)
Disease	attention deficit hyperactivity disorder, substance abuse, antisocial behaviour measurement	TET2 BNC2 UBAP2L TLR4 DOCK10 NFAT5 KDM4B PRRC2B SORL1	5.00e-04	801	85	9	EFO_0003888, EFO_0007052, MONDO_0002491
Disease	leukemia	CSF3R PRKCZ STAT3	5.43e-04	55	85	3	C0023418
Disease	creatinine measurement	TET2 KIF26B ETS1 PRKCZ FH NFAT5 UNC80 STAT3 RCAN2 SORL1	5.77e-04	995	85	10	EFO_0004518
Disease	colon cancer (is_marker_for)	MTUS1 KDM5C STAT3	6.68e-04	59	85	3	DOID:219 (is_marker_for)
Disease	psoriasis vulgaris	KCNH7 ETS1 CDKAL1	7.36e-04	61	85	3	EFO_1001494
Disease	stomach cancer (is_marker_for)	TET2 KDM5C STAT3 KDM4B	7.70e-04	142	85	4	DOID:10534 (is_marker_for)
Disease	Down syndrome (implicated_via_orthology)	RCAN2 DYRK3	8.40e-04	15	85	2	DOID:14250 (implicated_via_orthology)
Disease	breast cancer (is_implicated_in)	KDM4C TLR4 STAT3 KDM4B	9.44e-04	150	85	4	DOID:1612 (is_implicated_in)
Disease	Colorectal Carcinoma	TET2 LIG3 CACNB2 TLR4 TENM1 PRKCZ GREM1 SORL1	9.49e-04	702	85	8	C0009402
Disease	T-Cell Lymphoma	KDM4C STAT3	9.59e-04	16	85	2	C0079772
Disease	diet measurement, HOMA-B	FAT3 NFAT5	1.36e-03	19	85	2	EFO_0004469, EFO_0008111
Disease	daytime rest measurement	FRMD4A KIF26B C2orf88 TLR4 FSHR	1.65e-03	295	85	5	EFO_0007828
Disease	HIV-1 infection, Susceptibility to viral and mycobacterial infections	KDM4C FRMPD1	1.66e-03	21	85	2	EFO_0000180, Orphanet_391311
Disease	sex interaction measurement, cerebral amyloid angiopathy	C2orf88 GALNT13	1.66e-03	21	85	2	EFO_0006790, EFO_0008343
Disease	uric acid measurement	TET2 FAT3 AKAP13 ANKRD50 NFAT5 KDM4B PRRC2B	1.91e-03	610	85	7	EFO_0004761
Disease	Autism Spectrum Disorders	JARID2 GLRA2 UNC80	1.92e-03	85	85	3	C1510586
Disease	Reperfusion Injury	TLR4 ETS1 STAT3	2.19e-03	89	85	3	C0035126
Disease	colon adenocarcinoma (is_marker_for)	TET2 STAT3	2.36e-03	25	85	2	DOID:234 (is_marker_for)
Disease	ulcerative colitis	ADAD1 TET2 ETS1 CDKAL1 STAT3	2.86e-03	335	85	5	EFO_0000729

Protein segments in the cluster

Peptide	Gene	Start	Entry
KHMCKETMSFPLNSP	BHLHB9	406	Q6PI77
IQMEAAPFRSKEPCM	CATSPERG	146	Q6ZRH7
RQPSMSETMPLYTLC	CTDP1	836	Q9Y5B0
PPSTCQMAQLEKMSE	EPDR1	206	Q9UM22
MVFPAKRFCLVPSME	AASDHPPT	1	Q9NRN7
SLSSPVEQDCKMMFP	CTAGE6	596	Q86UF2
SLSSPVEQDCKMMFP	CTAGE15	596	A4D2H0
CPGMPSKEQRQTLMF	DDX4	466	Q9NQI0
KVPGCNMMFSSVRSR	BNC2	1066	Q6ZN30
YPMAITPTQKRRSCM	MASTL	691	Q96GX5
MIFRDMAECSTPLPE	AKAP13	2381	Q12802
NPAMMEKSIFCTEPT	ADAD1	296	Q96M93
QMPAESQCKIMIPSA	ANKRD50	1321	Q9ULJ7
DTPMNRKSMPEADFS	QDPR	186	P09417
MVQRDMSKSPPTAAA	CACNB2	1	Q08289
RSKTAMSKCPIFPMA	DENND4A	1571	Q7Z401
MSKCPIFPMARSIST	DENND4A	1576	Q7Z401
FCSPRPESMAIYKSM	NTN1	151	O95631
MPAPSMDCDVSTLVA	RCAN2	1	Q14206
MSRTVNPPRSSMCAV	RAB28	206	P51157
MTTEEAMPEKAKCPT	IQCM	1	A0A1B0GVH7
VNSIKYMERCMSPPI	HACL1	181	Q9UJ83
YMERCMSPPISMAET	HACL1	186	Q9UJ83
KVSESMQYPFKPCMR	MBTD1	276	Q05BQ5
PKKFTTMMVTLNCPE	GREM1	146	O60565
STDKTMCMSTPVLEP	MTUS1	421	Q9ULD2
MCMSTPVLEPTKVTF	MTUS1	426	Q9ULD2
MTGFSRPDVMQKPCT	KCNH7	51	Q9NS40
LCPKDMMLTQAPSSV	CFAP65	61	Q6ZU64
ESCDVPPLKSMAMRL	CFAP65	701	Q6ZU64
PMKTNITVYPCIAMS	KIF26B	1386	Q2KJY2
RECTMDLSEFMNPSP	CLCN7	731	P51798
RKESTSEQMPSFPEM	ECPAS	546	Q5VYK3
CADVPLLTPSSKEMM	ETS1	31	P14921
RQPPTSMKFRTDMAF	GPATCH3	496	Q96I76
IMKLVNCPETFTPDM	PDPR	351	Q8NCN5
CLTTINIMTSPNMPK	NIPBL	1311	Q6KC79
PSCKIMTFRPTMEEF	KDM4B	11	O94953
NPSCKIMTFRPSMEE	KDM4C	11	Q9H3R0
REAPDSDPVMSMQKT	LCA10	141	Q71F78
NPMNMCSEESERPAK	MIER3	466	Q7Z3K6
SLMTPVQPMLAEACK	LIG3	476	P49916
SPARPCSFEEAMKAM	NFAT5	561	O94916
CLSTDAAAPQTMVMP	BBS9	826	Q3SYG4
CPMKSAPVMLTLSDS	RBBP5	126	Q15291
PSEEDKMVPTMQDCS	GALNT13	526	Q8IUC8
LFTCEPITVPRCMKM	FZD6	21	O60353
MPQMCKATSAALPQS	FRMD4A	976	Q9P2Q2
LNDRMCDPETKPTSM	ADAMTS9	1086	Q9P2N4
CVTSSFIPVKPFNMM	DOCK10	631	Q96BY6
SQCDSASSRMVLPMP	CDKAL1	536	Q5VV42
TKSTNPASRVMEMEP	FRMPD1	911	Q5SYB0
SIMPGKVNPTQCEAM	FH	366	P07954
EDMKATCVNMTSPNP	COL6A5	2501	A8TX70
CKEPDMTTMGQFVLS	FAT3	1626	Q8TDW7
SPVCMDSFQPMDDSL	GON4L	476	Q3T8J9
CVPVSMKKMSRTSPA	ANK3	4321	Q12955
TSMSPQLCLDPMDVV	CSF3R	211	Q99062
SCPMDLKNFPMDVQT	GLRA2	171	P23416
NTSKEMSCFSDFPMP	FMO2	61	Q99518
MFCVTPPELETKMNI	PRPSAP2	1	O60256
LPCSFSILEEQPMDM	DDI2	306	Q5TDH0
TMRIPVESAPMFSAK	FCRLB	171	Q6BAA4
YMKVSICLPMDIDSP	FSHR	511	P23945
STAPPMCLQDVESMN	CES3	91	Q6UWW8
QQMDCSSVPIVMLPK	DNA2	411	P51530
ITLPAMFPSMCEKMR	DYSF	446	O75923
MEPESCSPKNNMIVG	GSTCD	616	Q8NEC7
MMIDETKCPPCSNVL	DYRK3	36	O43781
NIMSMCFSKEPAPAE	JARID2	831	Q92833
PSTMTDKEMESPECM	TSEN2	426	Q8NCE0
MRPKKMPSASCVYNV	SORL1	1576	Q92673
PCTVSMVALKFMPES	SV2B	286	Q7L1I2
CPNFSDVMGNKTLPM	FER1L5	806	A0AVI2
NVCRKFPRDMKAMSP	RHOBTB2	641	Q9BYZ6
VSCMEATPNPMESLR	PPP1R32	381	Q7Z5V6
DRIMNSFSVMPSPKV	TUBB1	161	Q9H4B7
DQPDCLLSVTMPSMV	TENM1	1906	Q9UKZ4
PCSLPMLSVDMENKE	SAMD13	16	Q5VXD3
PRKMAFAKMDPSCTV	ATG4D	381	Q86TL0
KVIMEMSTCEEPRSP	UHRF1BP1L	86	A0JNW5
DTCSEPVVAMKPSLM	TAS1R3	101	Q7RTX0
EVLTRPMTAPQMSRC	UNC80	2416	Q8N2C7
PSSTMMEVFLQEKSP	UBAP2L	426	Q14157
TSTMPGMICKNPDLE	MYCN	6	P04198
LMKSAFVVERQPCMP	STAT3	316	P40763
MLPAFMCSPKSSENQ	PRRC2B	281	Q5JSZ5
MGCMKSKQTFPFPTI	C2orf88	1	Q9BSF0
PSISKSDLMLQCKMP	ZNF717	291	Q9BY31
SSSNIPCVPKDLLMM	UBR3	191	Q6ZT12
MTVPLCSEKTRPMSE	TET2	496	Q6N021
RMECATPSDKQGMPV	TLR4	606	O00206
LCSMPESTEIMKRPK	TTLL7	531	Q6ZT98
FSRMPICEHMVESPT	SPINK4	31	O60575
EELSHSPEPCTKMTM	KDM5C	296	P41229
VPLTCRKHMDSVMPS	PRKCZ	176	Q05513
CQQPKMLSSPEDTMY	MYO3B	1261	Q8WXR4