Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhigh-affinity IgG receptor activity

FCGR1A FCGR1BP

6.82e-072172GO:0019771
GeneOntologyMolecularFunctionleukotriene receptor binding

FCGR1A FCGR1BP

6.82e-072172GO:0031774
GeneOntologyMolecularFunctionIgG receptor activity

FCGR1A FCGR1BP

1.43e-057172GO:0019770
GeneOntologyMolecularFunctionIgG binding

FCGR1A FCGR1BP

3.74e-0511172GO:0019864
GeneOntologyMolecularFunctionimmunoglobulin receptor activity

FCGR1A FCGR1BP

6.17e-0514172GO:0019763
GeneOntologyMolecularFunctionimmunoglobulin binding

FCGR1A FCGR1BP

4.23e-0436172GO:0019865
GeneOntologyMolecularFunctionreceptor tyrosine kinase binding

CBLB DNAJA3

2.61e-0390172GO:0030971
GeneOntologyMolecularFunctionprotein tyrosine kinase binding

CBLB DNAJA3

6.99e-03149172GO:1990782
GeneOntologyMolecularFunctionimmune receptor activity

FCGR1A FCGR1BP

8.51e-03165172GO:0140375
GeneOntologyBiologicalProcesstype III hypersensitivity

FCGR1A FCGR1BP

6.38e-065172GO:0001802
GeneOntologyBiologicalProcessregulation of type III hypersensitivity

FCGR1A FCGR1BP

6.38e-065172GO:0001803
GeneOntologyBiologicalProcesspositive regulation of type III hypersensitivity

FCGR1A FCGR1BP

6.38e-065172GO:0001805
GeneOntologyBiologicalProcesspositive regulation of type II hypersensitivity

FCGR1A FCGR1BP

2.87e-0510172GO:0002894
GeneOntologyBiologicalProcesspositive regulation of type IIa hypersensitivity

FCGR1A FCGR1BP

2.87e-0510172GO:0001798
GeneOntologyBiologicalProcessregulation of type II hypersensitivity

FCGR1A FCGR1BP

3.50e-0511172GO:0002892
GeneOntologyBiologicalProcessregulation of type IIa hypersensitivity

FCGR1A FCGR1BP

3.50e-0511172GO:0001796
GeneOntologyBiologicalProcesspenetration of zona pellucida

PITHD1 HYAL3

4.96e-0513172GO:0007341
GeneOntologyBiologicalProcessantibody-dependent cellular cytotoxicity

FCGR1A FCGR1BP

4.96e-0513172GO:0001788
GeneOntologyBiologicalProcesspositive regulation of hypersensitivity

FCGR1A FCGR1BP

6.67e-0515172GO:0002885
GeneOntologyBiologicalProcesstype IIa hypersensitivity

FCGR1A FCGR1BP

6.67e-0515172GO:0001794
GeneOntologyBiologicalProcesstype II hypersensitivity

FCGR1A FCGR1BP

6.67e-0515172GO:0002445
GeneOntologyBiologicalProcesspositive regulation of acute inflammatory response to antigenic stimulus

FCGR1A FCGR1BP

8.63e-0517172GO:0002866
GeneOntologyBiologicalProcesspositive regulation of phagocytosis, engulfment

FCGR1A FCGR1BP

9.71e-0518172GO:0060100
GeneOntologyBiologicalProcesspositive regulation of membrane invagination

FCGR1A FCGR1BP

9.71e-0518172GO:1905155
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen via MHC class I

FCGR1A FCGR1BP

9.71e-0518172GO:0042590
GeneOntologyBiologicalProcessregulation of hypersensitivity

FCGR1A FCGR1BP

1.08e-0419172GO:0002883
GeneOntologyBiologicalProcesspositive regulation of inflammatory response to antigenic stimulus

FCGR1A FCGR1BP

1.60e-0423172GO:0002863
GeneOntologyBiologicalProcessregulation of phagocytosis, engulfment

FCGR1A FCGR1BP

1.75e-0424172GO:0060099
GeneOntologyBiologicalProcessregulation of membrane invagination

FCGR1A FCGR1BP

1.90e-0425172GO:1905153
GeneOntologyBiologicalProcesshypersensitivity

FCGR1A FCGR1BP

1.90e-0425172GO:0002524
GeneOntologyBiologicalProcessregulation of acute inflammatory response to antigenic stimulus

FCGR1A FCGR1BP

2.22e-0427172GO:0002864
GeneOntologyBiologicalProcessimmune response-regulating cell surface receptor signaling pathway

FCGR1A FCGR1BP CBLB UBR2

2.54e-04393174GO:0002768
GeneOntologyBiologicalProcesspositive regulation of myeloid leukocyte mediated immunity

FCGR1A FCGR1BP

2.74e-0430172GO:0002888
GeneOntologyBiologicalProcessFc-gamma receptor signaling pathway

FCGR1A FCGR1BP

4.65e-0439172GO:0038094
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen via MHC class I

FCGR1A FCGR1BP

5.14e-0441172GO:0002474
GeneOntologyBiologicalProcesspositive regulation of acute inflammatory response

FCGR1A FCGR1BP

5.40e-0442172GO:0002675
GeneOntologyBiologicalProcessacute inflammatory response to antigenic stimulus

FCGR1A FCGR1BP

5.40e-0442172GO:0002438
GeneOntologyBiologicalProcessphagocytosis, recognition

FCGR1A FCGR1BP

5.40e-0442172GO:0006910
GeneOntologyBiologicalProcessretina development in camera-type eye

GRM6 LAMB2 CASZ1

6.46e-04211173GO:0060041
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous peptide antigen

FCGR1A FCGR1BP

7.05e-0448172GO:0002478
GeneOntologyBiologicalProcessregulation of T cell receptor signaling pathway

CBLB UBR2

9.25e-0455172GO:0050856
GeneOntologyBiologicalProcesspositive regulation of immunoglobulin mediated immune response

FCGR1A FCGR1BP

9.59e-0456172GO:0002891
GeneOntologyBiologicalProcesspositive regulation of B cell mediated immunity

FCGR1A FCGR1BP

9.59e-0456172GO:0002714
GeneOntologyBiologicalProcessantigen processing and presentation of exogenous antigen

FCGR1A FCGR1BP

1.03e-0358172GO:0019884
GeneOntologyBiologicalProcessregulation of inflammatory response to antigenic stimulus

FCGR1A FCGR1BP

1.14e-0361172GO:0002861
GeneOntologyBiologicalProcessFc receptor signaling pathway

FCGR1A FCGR1BP

1.17e-0362172GO:0038093
GeneOntologyBiologicalProcessimmune response-regulating signaling pathway

FCGR1A FCGR1BP CBLB UBR2

1.37e-03615174GO:0002764
GeneOntologyBiologicalProcessregulation of acute inflammatory response

FCGR1A FCGR1BP

1.37e-0367172GO:0002673
GeneOntologyBiologicalProcessneuromuscular junction development

DNAJA3 LAMB2

1.41e-0368172GO:0007528
GeneOntologyBiologicalProcessregulation of immune response

FCGR1A FCGR1BP CBLB DNAJA3 UBR2

1.45e-031085175GO:0050776
GeneOntologyBiologicalProcessphagocytosis, engulfment

FCGR1A FCGR1BP

1.45e-0369172GO:0006911
GeneOntologyBiologicalProcessnegative regulation of TOR signaling

UBR2 WDR59

1.67e-0374172GO:0032007
GeneOntologyBiologicalProcessantigen processing and presentation of peptide antigen

FCGR1A FCGR1BP

1.76e-0376172GO:0048002
GeneOntologyBiologicalProcessregulation of antigen receptor-mediated signaling pathway

CBLB UBR2

1.80e-0377172GO:0050854
GeneOntologyBiologicalProcessregulation of vesicle-mediated transport

FCGR1A FCGR1BP CBLB HYAL3

1.84e-03667174GO:0060627
GeneOntologyBiologicalProcessplasma membrane invagination

FCGR1A FCGR1BP

1.85e-0378172GO:0099024
GeneOntologyBiologicalProcessregulation of immunoglobulin mediated immune response

FCGR1A FCGR1BP

1.90e-0379172GO:0002889
GeneOntologyBiologicalProcessregulation of B cell mediated immunity

FCGR1A FCGR1BP

1.90e-0379172GO:0002712
GeneOntologyBiologicalProcessregulation of myeloid leukocyte mediated immunity

FCGR1A FCGR1BP

1.99e-0381172GO:0002886
GeneOntologyBiologicalProcessmembrane invagination

FCGR1A FCGR1BP

2.30e-0387172GO:0010324
GeneOntologyBiologicalProcessreceptor-mediated endocytosis

FCGR1A FCGR1BP CBLB

2.48e-03337173GO:0006898
GeneOntologyBiologicalProcesspositive regulation of immune system process

FCGR1A FCGR1BP CBLB DNAJA3 UBR2

2.64e-031242175GO:0002684
GeneOntologyBiologicalProcesspositive regulation of phagocytosis

FCGR1A FCGR1BP

2.96e-0399172GO:0050766
GeneOntologyBiologicalProcessinflammatory response to antigenic stimulus

FCGR1A FCGR1BP

3.20e-03103172GO:0002437
GeneOntologyBiologicalProcessregulation of endocytosis

FCGR1A FCGR1BP CBLB

3.72e-03389173GO:0030100
GeneOntologyBiologicalProcesspositive regulation of immune response

FCGR1A FCGR1BP CBLB UBR2

4.34e-03845174GO:0050778
GeneOntologyBiologicalProcesspositive regulation of protein ubiquitination

CBLB DNAJA3

4.60e-03124172GO:0031398
GeneOntologyBiologicalProcesscamera-type eye development

GRM6 LAMB2 CASZ1

4.80e-03426173GO:0043010
GeneOntologyBiologicalProcesscellular senescence

DNAJA3 NEK6

4.89e-03128172GO:0090398
GeneOntologyBiologicalProcessregulation of phagocytosis

FCGR1A FCGR1BP

5.50e-03136172GO:0050764
GeneOntologyBiologicalProcessantigen processing and presentation

FCGR1A FCGR1BP

5.74e-03139172GO:0019882
GeneOntologyBiologicalProcessmembrane organization

FCGR1A FCGR1BP DNAJA3 NEK6

5.74e-03914174GO:0061024
GeneOntologyCellularComponentclathrin-coated endocytic vesicle membrane

FCGR1A FCGR1BP

1.85e-0379172GO:0030669
GeneOntologyCellularComponentclathrin-coated endocytic vesicle

FCGR1A FCGR1BP

3.00e-03101172GO:0045334
GeneOntologyCellularComponentneuromuscular junction

DNAJA3 LAMB2

3.67e-03112172GO:0031594
GeneOntologyCellularComponentcentriolar satellite

NAA40 NEK6

4.76e-03128172GO:0034451
MousePhenodecreased susceptibility to autoimmune hemolytic anemia

FCGR1A FCGR1BP

9.30e-065142MP:0004828
MousePhenoabnormal macrophage antigen presentation

FCGR1A FCGR1BP

4.17e-0510142MP:0002454
MousePhenoabnormal dendritic cell differentiation

FCGR1A FCGR1BP

1.75e-0420142MP:0008115
DomainIg_2

FCGR1A FCGR1BP

1.97e-0373172PF13895
DomainGalactose-bd-like

PITHD1 LAMB2

3.24e-0394172IPR008979
DomainZnf_RING/FYVE/PHD

CBLB UBR2 WDR59

7.76e-03459173IPR013083
DomainImmunoglobulin

FCGR1A FCGR1BP

1.27e-02190172IPR013151
Domainig

FCGR1A FCGR1BP

1.27e-02190172PF00047
DomainIg_sub2

FCGR1A FCGR1BP

1.89e-02235172IPR003598
DomainEGF

LAMB2 HYAL3

1.89e-02235172SM00181
DomainIGc2

FCGR1A FCGR1BP

1.89e-02235172SM00408
DomainEGF-like_dom

LAMB2 HYAL3

2.11e-02249172IPR000742
DomainEGF_1

LAMB2 HYAL3

2.21e-02255172PS00022
DomainEGF-like_CS

LAMB2 HYAL3

2.30e-02261172IPR013032
Domainzf-C2H2

ZNF552 CASZ1 TRPS1

2.35e-02693173PF00096
DomainEGF_2

LAMB2 HYAL3

2.37e-02265172PS01186
PathwayREACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION

FCGR1A FCGR1BP CBLB UBR2

1.46e-04343124MM15712
PathwayREACTOME_CLASS_I_MHC_MEDIATED_ANTIGEN_PROCESSING_PRESENTATION

FCGR1A FCGR1BP CBLB UBR2

2.19e-04381124M1066
PathwayWP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY

FCGR1A FCGR1BP

6.73e-0446122MM15837
PathwayREACTOME_FCGR_ACTIVATION

FCGR1A FCGR1BP

7.33e-0448122MM17214
PathwayREACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES

FCGR1A FCGR1BP

7.33e-0448122MM14528
PathwayREACTOME_CROSS_PRESENTATION_OF_SOLUBLE_EXOGENOUS_ANTIGENS_ENDOSOMES

FCGR1A FCGR1BP

7.95e-0450122M510
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

FCGR1A FCGR1BP

9.97e-0456122MM14815
PathwayREACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION

FCGR1A FCGR1BP

1.83e-0376122MM14526
PathwayREACTOME_ADAPTIVE_IMMUNE_SYSTEM

FCGR1A FCGR1BP CBLB UBR2

2.39e-03719124MM14540
PathwayREACTOME_INTERFERON_GAMMA_SIGNALING

FCGR1A FCGR1BP

3.02e-0398122M965
PathwayREACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION

FCGR1A FCGR1BP

3.52e-03106122M518
PathwayREACTOME_ADAPTIVE_IMMUNE_SYSTEM

FCGR1A FCGR1BP CBLB UBR2

4.00e-03828124M1058
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

FCGR1A FCGR1BP

4.06e-03114122MM14814
Pubmed

Single Nucleotide Polymorphisms of the High Affinity IgG Receptor FcγRI Reduce Immune Complex Binding and Downstream Effector Functions.

FCGR1A FCGR1BP

2.25e-07217228814603
Pubmed

The FcRgamma chain is not essential for induction of experimental allergic encephalomyelitis (EAE) or anti-myelin antibody-mediated exacerbation of EAE.

FCGR1A FCGR1BP

2.25e-07217215835266
Pubmed

Amelioration of crescentic glomerulonephritis by RhoA kinase inhibitor, Fasudil, through podocyte protection and prevention of leukocyte migration.

FCGR1A FCGR1BP

2.25e-07217218245810
Pubmed

FcR gamma-chain is essential for both surface expression and function of human Fc gamma RI (CD64) in vivo.

FCGR1A FCGR1BP

2.25e-0721728611682
Pubmed

Reconstitution of allogeneic hemopoietic stem cells: the essential role of FcR gamma and the TCR beta-chain-FCp33 complex.

FCGR1A FCGR1BP

2.25e-07217216849450
Pubmed

Extracellular mutations of non-obese diabetic mouse FcgammaRI modify surface expression and ligand binding.

FCGR1A FCGR1BP

2.25e-0721728663283
Pubmed

Direct targeting of genetically modified tumour cells to Fc gammaRI triggers potent tumour cytotoxicity.

FCGR1A FCGR1BP

2.25e-07217216409296
Pubmed

Features and protective efficacy of human mAbs targeting Mycobacterium tuberculosis arabinomannan.

FCGR1A FCGR1BP

2.25e-07217237733444
Pubmed

Modulating IgG effector function by Fc glycan engineering.

FCGR1A FCGR1BP

2.25e-07217228289219
Pubmed

The interaction of N-glycans in Fcγ receptor I α-chain with Escherichia coli K1 outer membrane protein A for entry into macrophages: experimental and computational analysis.

FCGR1A FCGR1BP

2.25e-07217225231998
Pubmed

Lentivirus-mediated knockdown of FcγRI (CD64) attenuated lupus nephritis via inhibition of NF-κB regulating NLRP3 inflammasome activation in MRL/lpr mice.

FCGR1A FCGR1BP

2.25e-07217230190171
Pubmed

Biochemical characterization of murine Fc gamma RI.

FCGR1A FCGR1BP

2.25e-0721728478020
Pubmed

FcγR-binding affinity of monoclonal murine IgG1s carrying different N-linked Fc oligosaccharides.

FCGR1A FCGR1BP

2.25e-07217231554601
Pubmed

Amelioration of Lupus Serum-Induced Skin Inflammation in CD64-Deficient Mice.

FCGR1A FCGR1BP

2.25e-07217235273604
Pubmed

IgG3-mediated enhancement of the antibody response is normal in Fc gammaRI-deficient mice.

FCGR1A FCGR1BP

2.25e-07217216305642
Pubmed

Congenic mapping of the insulin-dependent diabetes (Idd) gene, Idd10, localizes two genes mediating the Idd10 effect and eliminates the candidate Fcgr1.

FCGR1A FCGR1BP

2.25e-0721729257847
Pubmed

Fcγ receptor I alpha chain (CD64) expression in macrophages is critical for the onset of meningitis by Escherichia coli K1.

FCGR1A FCGR1BP

2.25e-07217221124939
Pubmed

Mouse FcgammaRI: identification and functional characterization of five new alleles.

FCGR1A FCGR1BP

2.25e-07217210752630
Pubmed

Macrophages eliminate circulating tumor cells after monoclonal antibody therapy.

FCGR1A FCGR1BP

2.25e-07217224430180
Pubmed

CD64 plays a key role in diabetic wound healing.

FCGR1A FCGR1BP

2.25e-07217238524127
Pubmed

Fcγ Receptor Type I (CD64)-Mediated Impairment of the Capacity of Dendritic Cells to Activate Specific CD8 T Cells by IgG-opsonized Friend Virus.

FCGR1A FCGR1BP

2.25e-07217230744065
Pubmed

Serum anti-Fcgamma receptor autoantibodies in patients with alopecia areata.

FCGR1A FCGR1BP

2.25e-07217217124586
Pubmed

Molecular cloning and expression of the mouse high affinity Fc receptor for IgG.

FCGR1A FCGR1BP

2.25e-0721722136886
Pubmed

Gene organization of the human high affinity receptor for IgG, Fc gamma RI (CD64). Characterization and evidence for a second gene.

FCGR1A FCGR1BP

2.25e-0721721830050
Pubmed

FcRγ deficiency improves survival in experimental sepsis by down-regulating TLR4 signaling pathway.

FCGR1A FCGR1BP

2.25e-07217230552619
Pubmed

Neuronal FcγRI mediates acute and chronic joint pain.

FCGR1A FCGR1BP

2.25e-07217231211699
Pubmed

Sensory Neuron Expressed FcγRI Mediates Postinflammatory Arthritis Pain in Female Mice.

FCGR1A FCGR1BP

2.25e-07217235833115
Pubmed

Developmentally ordered appearance of a functional Fc gamma receptor on TCR V gamma 3 thymocytes. Evidence for stimulation-induced expression.

FCGR1A FCGR1BP

2.25e-0721728077658
Pubmed

Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity.

FCGR1A FCGR1BP

2.25e-07217238885133
Pubmed

Linkage on chromosome 3 of autoimmune diabetes and defective Fc receptor for IgG in NOD mice.

FCGR1A FCGR1BP

2.25e-0721728480181
Pubmed

Differential gene expression modulated by the cytoplasmic domain of Fc gamma RIa (CD64) alpha-chain.

FCGR1A FCGR1BP

2.25e-07217215528358
Pubmed

Fc Effector Function Contributes to the Activity of Human Anti-CTLA-4 Antibodies.

FCGR1A FCGR1BP

2.25e-07217229576375
Pubmed

Functional characteristics of the high affinity IgG receptor, FcγRI.

FCGR1A FCGR1BP

2.25e-07217221325219
Pubmed

Fc receptors and the common gamma-chain in experimental autoimmune encephalomyelitis.

FCGR1A FCGR1BP

2.25e-07217214991835
Pubmed

Definition of interferon gamma-response elements in a novel human Fc gamma receptor gene (Fc gamma RIb) and characterization of the gene structure.

FCGR1A FCGR1BP

2.25e-0721721402657
Pubmed

Novel Fc gamma receptor I family gene products in human mononuclear cells.

FCGR1A FCGR1BP

2.25e-0721721430234
Pubmed

The involvement of FcR mechanisms in antibody-mediated rejection.

FCGR1A FCGR1BP

2.25e-07217218049118
Pubmed

Residual LCMV antigen in transiently CD4+ T cell-depleted mice induces high levels of virus-specific antibodies but only limited B-cell memory.

FCGR1A FCGR1BP

6.74e-07317230636035
Pubmed

Serine phosphorylation of FcγRI cytoplasmic domain directs lipid raft localization and interaction with protein 4.1G.

FCGR1A FCGR1BP

6.74e-07317222003208
Pubmed

Neonatal Fc receptor for IgG regulates mucosal immune responses to luminal bacteria.

FCGR1A FCGR1BP

6.74e-07317216841095
Pubmed

FcgammaRI ligation leads to a complex with BLT1 in lipid rafts that enhances rat lung macrophage antimicrobial functions.

FCGR1A FCGR1BP

6.74e-07317219657115
Pubmed

Nephrotoxic nephritis is mediated by Fcgamma receptors on circulating leukocytes and not intrinsic renal cells.

FCGR1A FCGR1BP

6.74e-07317212427132
Pubmed

Cutting Edge: Drebrin-Regulated Actin Dynamics Regulate IgE-Dependent Mast Cell Activation and Allergic Responses.

FCGR1A FCGR1BP

6.74e-07317226056254
Pubmed

The essential role of complement in antibody-mediated resistance to Salmonella.

FCGR1A FCGR1BP

6.74e-07317230179254
Pubmed

Fc-optimized antibodies elicit CD8 immunity to viral respiratory infection.

FCGR1A FCGR1BP

6.74e-07317233032297
Pubmed

The three genes of the human FCGR1 gene family encoding Fc gamma RI flank the centromere of chromosome 1 at 1p12 and 1q21.

FCGR1A FCGR1BP

6.74e-0731728697799
Pubmed

Transcriptional and post-transcriptional regulation of IκB-ζ upon engagement of the BCR, TLRs and FcγR.

FCGR1A FCGR1BP

6.74e-07317223728777
Pubmed

MicroRNA-127 inhibits lung inflammation by targeting IgG Fcγ receptor I.

FCGR1A FCGR1BP

6.74e-07317222287715
Pubmed

Tpl2 kinase regulates FcγR signaling and immune thrombocytopenia in mice.

FCGR1A FCGR1BP

6.74e-07317223898046
Pubmed

Localization of FCGR1 encoding Fcgamma receptor class I in primates: molecular evidence for two pericentric inversions during the evolution of human chromosome 1.

FCGR1A FCGR1BP

6.74e-0731729763663
Pubmed

FcγRI mediates serum amyloid P inhibition of fibrocyte differentiation.

FCGR1A FCGR1BP

6.74e-07317222493081
Pubmed

FcgammaR-induced production of superoxide and inflammatory cytokines is differentially regulated by SHIP through its influence on PI3K and/or Ras/Erk pathways.

FCGR1A FCGR1BP

6.74e-07317216543474
Pubmed

C1q-Dependent Dendritic Cell Cross-Presentation of In Vivo-Formed Antigen-Antibody Complexes.

FCGR1A FCGR1BP

6.74e-07317228432146
Pubmed

Unique monoclonal antibodies define expression of Fc gamma RI on macrophages and mast cell lines and demonstrate heterogeneity among subcutaneous and other dendritic cells.

FCGR1A FCGR1BP

6.74e-07317212594281
Pubmed

Toxicity of an Fc-engineered anti-CD40 antibody is abrogated by intratumoral injection and results in durable antitumor immunity.

FCGR1A FCGR1BP

6.74e-07317230297432
Pubmed

FcgammaRI up-regulation induced by local adenoviral-mediated interferon-gamma production aggravates chondrocyte death during immune complex-mediated arthritis.

FCGR1A FCGR1BP

6.74e-07317212875993
Pubmed

Development of proteoglycan-induced arthritis is critically dependent on Fcgamma receptor type III expression.

FCGR1A FCGR1BP

6.74e-07317215880819
Pubmed

Escherichia coli K1 induces pterin production for enhanced expression of Fcγ receptor I to invade RAW 264.7 macrophages.

FCGR1A FCGR1BP

6.74e-07317224161960
Pubmed

A new mouse expressing human Fcγ receptors to better predict therapeutic efficacy of human anti-cancer antibodies.

FCGR1A FCGR1BP

6.74e-07317228924242
Pubmed

Fcgamma receptor-mediated induction of dendritic cell maturation and major histocompatibility complex class I-restricted antigen presentation after immune complex internalization.

FCGR1A FCGR1BP

6.74e-0731729892619
Pubmed

Both Fcgamma receptor I and Fcgamma receptor III mediate disease in accelerated nephrotoxic nephritis.

FCGR1A FCGR1BP

6.74e-07317212707052
Pubmed

Glycoprotein VI-dependent and -independent pathways of thrombus formation in vivo.

FCGR1A FCGR1BP

1.35e-06417216455953
Pubmed

Identification of the mouse IgG3 receptor: implications for antibody effector function at the interface between innate and adaptive immunity.

FCGR1A FCGR1BP

1.35e-0641729551950
Pubmed

Fc receptor-mediated antibody regulation of T cell immunity against intracellular pathogens.

FCGR1A FCGR1BP

1.35e-06417212898452
Pubmed

Markedly different pathogenicity of four immunoglobulin G isotype-switch variants of an antierythrocyte autoantibody is based on their capacity to interact in vivo with the low-affinity Fcgamma receptor III.

FCGR1A FCGR1BP

1.35e-06417210770797
Pubmed

Universal vaccine based on ectodomain of matrix protein 2 of influenza A: Fc receptors and alveolar macrophages mediate protection.

FCGR1A FCGR1BP

1.35e-06417221169548
Pubmed

The Fc receptor gamma-chain and the tyrosine kinase Syk are essential for activation of mouse platelets by collagen.

FCGR1A FCGR1BP

1.35e-0641729171347
Pubmed

Three genes for the human high affinity Fc receptor for IgG (Fc gamma RI) encode four distinct transcription products.

FCGR1A FCGR1BP

1.35e-0641721379234
Pubmed

Fcgamma receptor cross-linking stimulates cell proliferation of macrophages via the ERK pathway.

FCGR1A FCGR1BP

1.35e-06417219996316
Pubmed

A critical role for Syk protein tyrosine kinase in Fc receptor-mediated antigen presentation and induction of dendritic cell maturation.

FCGR1A FCGR1BP

1.35e-06417212517949
Pubmed

Colony-stimulating factor-1-dependent macrophages are responsible for IVIG protection in antibody-induced autoimmune disease.

FCGR1A FCGR1BP

1.35e-06417212705859
Pubmed

The high-affinity IgG receptor, FcgammaRI, plays a central role in antibody therapy of experimental melanoma.

FCGR1A FCGR1BP

1.35e-06417216452176
Pubmed

Evidence for Cd101 but not Fcgr1 as candidate for type 1 diabetes locus, Idd10.

FCGR1A FCGR1BP

1.35e-06417215850792
Pubmed

The mouse Fc receptor for IgG (Ly-17): molecular cloning and specificity.

FCGR1A FCGR1BP

1.35e-0641722957319
Pubmed

Coordinate expression of activating Fc gamma receptors I and III and inhibiting Fc gamma receptor type II in the determination of joint inflammation and cartilage destruction during immune complex-mediated arthritis.

FCGR1A FCGR1BP

1.35e-06417212528127
Pubmed

Mouse immune thrombocytopenia is associated with Th1 bias and expression of activating Fcγ receptors.

FCGR1A FCGR1BP

1.35e-06417228028748
Pubmed

Human immunoglobulin G hinge regulates agonistic anti-CD40 immunostimulatory and antitumour activities through biophysical flexibility.

FCGR1A FCGR1BP

1.35e-06417231562320
Pubmed

Dynamic macrophage "probing" is required for the efficient capture of phagocytic targets.

FCGR1A FCGR1BP

1.35e-06417221135140
Pubmed

Fc receptor regulation of protective immunity against Chlamydia trachomatis.

FCGR1A FCGR1BP

1.35e-06417211872097
Pubmed

C-reactive protein-mediated suppression of nephrotoxic nephritis: role of macrophages, complement, and Fcgamma receptors.

FCGR1A FCGR1BP

1.35e-06417217182593
Pubmed

Abolition of anti-glomerular basement membrane antibody-mediated glomerulonephritis in FcRgamma-deficient mice.

FCGR1A FCGR1BP

1.35e-06417210760808
Pubmed

Adenovirus-mediated human immunodeficiency virus-1 Nef expression in human monocytes/macrophages and effect of Nef on downmodulation of Fcgamma receptors and expression of monokines.

FCGR1A FCGR1BP

1.35e-0641729490697
Pubmed

Signaling through mutants of the IgA receptor CD89 and consequences for Fc receptor gamma-chain interaction.

FCGR1A FCGR1BP

1.35e-06417216517729
Pubmed

Immune complex-loaded dendritic cells are superior to soluble immune complexes as antitumor vaccine.

FCGR1A FCGR1BP

1.35e-06417216585547
Pubmed

Unveiling skin macrophage dynamics explains both tattoo persistence and strenuous removal.

FCGR1A FCGR1BP

1.35e-06417229511065
Pubmed

The serine/threonine kinase Akt Promotes Fc gamma receptor-mediated phagocytosis in murine macrophages through the activation of p70S6 kinase.

FCGR1A FCGR1BP

1.35e-06417215485887
Pubmed

Fcgamma receptor deficiency confers protection against atherosclerosis in apolipoprotein E knockout mice.

FCGR1A FCGR1BP

2.25e-06517217053192
Pubmed

The murine Fc receptor for immunoglobulin: purification, partial amino acid sequence, and isolation of cDNA clones.

FCGR1A FCGR1BP

2.25e-0651722944118
Pubmed

Reversal of proinflammatory responses by ligating the macrophage Fcgamma receptor type I.

FCGR1A FCGR1BP

2.25e-0651729653099
Pubmed

C-reactive protein binding to murine leukocytes requires Fc gamma receptors.

FCGR1A FCGR1BP

2.25e-06517210640769
Pubmed

Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.

FCGR1A FCGR1BP

2.25e-06517219380812
Pubmed

Structure and mapping of the gene encoding mouse high affinity Fc gamma RI and chromosomal location of the human Fc gamma RI gene.

FCGR1A FCGR1BP

2.25e-0651721531670
Pubmed

Fc epsilonRI gamma can support T cell development and function in mice lacking endogenous TCR zeta-chain.

FCGR1A FCGR1BP

2.25e-0651729200458
Pubmed

Therapeutic Activity of Agonistic, Human Anti-CD40 Monoclonal Antibodies Requires Selective FcγR Engagement.

FCGR1A FCGR1BP

2.25e-06517227265505
Pubmed

IgG is elevated in obese white adipose tissue but does not induce glucose intolerance via Fcγ-receptor or complement.

FCGR1A FCGR1BP

2.25e-06517228852207
Pubmed

Human IgG Fc domain engineering enhances antitoxin neutralizing antibody activity.

FCGR1A FCGR1BP

2.25e-06517224401277
Pubmed

Antibody isotype-specific engagement of Fcgamma receptors regulates B lymphocyte depletion during CD20 immunotherapy.

FCGR1A FCGR1BP

2.25e-06517216520392
Pubmed

Destructive arthritis in the absence of both FcgammaRI and FcgammaRIII.

FCGR1A FCGR1BP

2.25e-06517218354234
Pubmed

Role of FcRs in animal model of autoimmune bullous pemphigoid.

FCGR1A FCGR1BP

2.25e-06517216920981
Pubmed

A role for antibody and Fc receptor in the clearance of Brugia malayi microfilariae.

FCGR1A FCGR1BP

2.25e-06517211920579
CytobandEnsembl 112 genes in cytogenetic band chr3p21

LAMB2 HYAL3

6.00e-03316172chr3p21
CytobandEnsembl 112 genes in cytogenetic band chr1p36

PITHD1 CASZ1

2.58e-02681172chr1p36
GeneFamilyImmunoglobulin like domain containing

FCGR1A FCGR1BP

8.18e-03193132594
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

ZNF552 CASZ1 TRPS1

1.32e-0271813328
CoexpressionCAO_BLOOD_FLUZONE_AGE_05_14YO_1DY_UP

FCGR1A FCGR1BP

5.93e-066172M41151
CoexpressionQIU_PBMC_HEPTATITIS_B_SURFACE_ANTIGEN_AGE_UNDER50_NON_RESPONDERS_VS_RESPONDERS_35DY_UP

FCGR1A FCGR1BP

4.14e-0515172M40982
CoexpressionSALVADOR_MARTIN_PEDIATRIC_TBD_ANTI_TNF_THERAPY_NONRESPONDER_POST_TREATMENT_UP

FCGR1A FCGR1BP

1.28e-0426172M41741
CoexpressionPATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_93YO_VZV_CHALLENGE_6HR_TOP_30_DEG_UP

FCGR1A FCGR1BP

1.59e-0429172M40976
CoexpressionPATEL_SKIN_OF_BODY_ZOSTAVAX_AGE_70_93YO_VZV_CHALLENGED_POST_VACCINATION_VS_UNCHALLENGED_72HR_TOP_30_DEG_UP

FCGR1A FCGR1BP

1.70e-0430172M40975
CoexpressionGSE25123_WT_VS_PPARG_KO_MACROPHAGE_DN

FCGR1A FCGR1BP PITHD1

2.71e-04199173M7953
CoexpressionGSE2770_UNTREATED_VS_IL4_TREATED_ACT_CD4_TCELL_48H_UP

DNAJA3 LAMB2 NEK6

2.75e-04200173M6022
CoexpressionGSE2770_IL12_VS_TGFB_AND_IL12_TREATED_ACT_CD4_TCELL_48H_UP

CBLB PITHD1 UBR2

2.75e-04200173M6027
CoexpressionNAKAYA_PBMC_FLUAD_MALE_AGE_14_27YO_1D_POSTBOOST_VS_0D_PREIMM_MF59_ADJUVANTED_1DY_ATIV_UP

FCGR1A FCGR1BP

3.04e-0440172M40897
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CBLB USP31 TRPS1

2.95e-051611732849fbc9611af208241b33da3cd18290aafe426b
ToppCellAdult-Immune-interstitial_macrophage_(C1Q_positive)-D175|Adult / Lineage, Cell type, age group and donor

FCGR1A FCGR1BP TRPS1

4.46e-05185173ab5704b96f1d368911308797d10c7c52766ab134
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

CBLB UBR2 CASZ1

5.06e-05193173778fcf8448e81fe18972d97ea8a30ab036d16fe5
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP NEK6

5.06e-0519317352f5b0fbb8ca706206c65e7edbb1ddbd380aebae
ToppCellCaecum-Macrophage-LYVE1_Macrophage|Caecum / Region, Cell class and subclass

FCGR1A FCGR1BP LAMB2

5.45e-05198173a92c0cacb775aca6bbb302bd9e22c081a112a44d
ToppCellBronchial_Brush-Immune-Luminal_Macrophages|Immune / Tissue, Lineage and Cell class of Lung Cells from 10X

FCGR1A FCGR1BP NEK6

5.45e-0519817377f41f0e0895b7c732bab1fd2e047f2ed31cbd9d
ToppCellCaecum-(6)_Macrophage-(61)_LYVE1_Macrophage|Caecum / shred on region, Cell_type, and subtype

FCGR1A FCGR1BP LAMB2

5.45e-05198173e684c3934c163aef4d284b69435832d2c9614f2a
ToppCellmLN-(4)_Monocyte-(40)_Monocyte|mLN / shred on region, Cell_type, and subtype

FCGR1A FCGR1BP LAMB2

5.54e-05199173bcbb1eee8d79bf670dbe113094c3a292b135ce2f
ToppCellmLN-(4)_Monocyte|mLN / shred on region, Cell_type, and subtype

FCGR1A FCGR1BP LAMB2

5.54e-051991736795ff31f92580195c9db776951f99d647484d24
ToppCellmLN-Monocyte|mLN / Region, Cell class and subclass

FCGR1A FCGR1BP LAMB2

5.54e-05199173241f790cd5d8a9b2451333deecc826a673bae70a
ToppCellmLN-Monocyte-Monocyte|mLN / Region, Cell class and subclass

FCGR1A FCGR1BP LAMB2

5.54e-05199173dcee372774c169a3048bdaed3734b3215bf8ffad
ToppCellLPS_only-Hematopoietic_Myeloid-Granulocytic_cells-Mast-cells|LPS_only / Treatment groups by lineage, cell group, cell type

FCGR1A HYAL3 NEK6

5.62e-05200173afbbfe0b8e66df36c244935182cb26feeb31a085
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c2-CXCR4(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LAMB2 TRPS1

1.13e-03132172a1fda8c5287168c4f159203ed27cadfb4ce1b131
ToppCellPBMC-Severe-Myeloid-Classical_Monocyte-Classical_Monocyte-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FCGR1A FCGR1BP

1.21e-0313717212caa8ed7cc9e7a0f78c14ad5efe2fc28c3ce9be
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

1.29e-031411722d2c468783730d81e3cacb0336027ba0ce1e5f4f
ToppCellCOVID-19_Severe-dn_T|COVID-19_Severe / Disease condition and Cell class

CBLB TRPS1

1.30e-031421722008033881b9e1b20926c3508d6ebdb6f1a1528f
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FCGR1A FCGR1BP

1.32e-031431724c5a5db46beb8f2f3c40e8ed95911fbfea61bae0
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FCGR1A FCGR1BP

1.36e-03145172778655fffd73df101e656154a41b478a1b695116
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1BP NEK6

1.38e-031461721e81ad3d6d5d5ad2f0176d2a9593a954d38fa294
ToppCellTCGA-Breast|World / Sample_Type by Project: Shred V9

ZNF552 TRPS1

1.45e-0315017208686ba1acac5c58667bf62e2af84c691d6bbdfb
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_large-bowel / Manually curated celltypes from each tissue

CBLB TRPS1

1.49e-0315217295944864ce7539ff8de028f5700694931338f3ff
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar-Macro_c2-CCL3L1|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

1.59e-03157172a98d06cef80bfe8481b0940abce2b29675e45812
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRM6 NEK6

1.61e-03158172e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GRM6 NEK6

1.61e-03158172d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell356C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FCGR1A FCGR1BP

1.63e-03159172299e2162a82e31196d7f3a110c2db622349edfff
ToppCell356C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FCGR1A FCGR1BP

1.63e-031591720a3a363b30a8c741e1a3e2525725108d03c21776
ToppCellsaliva-Severe-critical_progression_d28-40-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

1.71e-03163172d005115aa1e1458b51de7eb719794617a4168608
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Pvalb-Pvalb_Tpbg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CASZ1 TRPS1

1.73e-03164172f0499e6c1b17c4df72b18b294e3b53ef723da2ac
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.75e-0316517211227bff52eed30b80937fdb1968d0b8e6d30365
ToppCellfacs-Marrow-Granulocytes-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.75e-03165172036f9749048e5e50769cc3210339bf4da469215d
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

1.77e-031661722a04915d534a83e65aa168435d6856125b5bdd78
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Myeloid-Macrophage-macrophage,_alveolar|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

1.77e-0316617228a44448a0b0d72459e8fe84ce5d666f16f514b3
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

FCGR1A FCGR1BP

1.80e-03167172820472887f43b42ae7e44513ca3d5465fb4f71a7
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

FCGR1A USP31

1.82e-03168172d7d19c93d1c3dd994e18e28d5f36ae7773ff5d7f
ToppCell3'_v3-bone_marrow-Myeloid_Mac-Intermediate_macrophages|bone_marrow / Manually curated celltypes from each tissue

LAMB2 NEK6

1.82e-031681728ade4d098aeecda2d80c1cad1cebe9a063eae948
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FCGR1BP NAA40

1.82e-03168172c3d2d573f21350a4a674faff30b06ff644d00ac3
ToppCell390C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

FCGR1A USP31

1.84e-03169172d2def7229fe9d6b0c70cfed349ede491c8c137a0
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Hematologic-coronary_vascular_endothelial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

USP31 CASZ1

1.84e-031691724e1322cc5e1733e9fb19e08f739a30206f43cea8
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|390C / Donor, Lineage, Cell class and subclass (all cells)

FCGR1A FCGR1BP

1.84e-031691722c851b2703c7b8b656026f996f5fc027e4a79b36
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Monocytic-Classical_Monocyte-Mono_c2-CD14-HLA-DPB1|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

1.84e-03169172d4bd489ebdb86e70ed5e3dbbe8518c6cae2197e5
ToppCellfacs-Marrow-B-cells-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.86e-0317017218cd941bf3ca7cc0b6af1317bd2619d283353de0
ToppCellfacs-Marrow-T-cells-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.86e-03170172ff68600b945b3a5437b14e5411b3db800d0ccbe5
ToppCellfacs-Marrow-T-cells-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.86e-03170172a78d9789c3e7c84a36e1bd380192d7aba4a4d443
ToppCellfacs-Marrow-B-cells-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.86e-031701726e82e41acd1299aa549a32ac036b39754abdf376
ToppCellwk_15-18-Hematologic-Myeloid-GMP|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

FCGR1A HYAL3

1.88e-031711724b8b67c289898ae114a07a2147b5a6f8ec9dd308
ToppCelldroplet-Marrow-nan-3m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.88e-03171172992df143d76f9e7fb1997a8996f61e941f0f9d4f
ToppCellILEUM-non-inflamed-(3)_MNP-(3)_mature_DC|(3)_MNP / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CASZ1 NEK6

1.88e-03171172341f9f79c1ed654ab347e25dc4936f89ffdf9617
ToppCellfacs-BAT-Fat-18m-Myeloid-nan|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.90e-0317217236fe66a8c0aecee7a19269be23210c0ed7abb155
ToppCell3'-GW_trimst-2-SmallIntestine-Hematopoietic-Myeloid-CLC+_Mast_cell|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GRM6 NEK6

1.92e-03173172b9dc42d629d13e63aada5ae49ba0cbb0952c5fe9
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Alveolar_Mac|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

FCGR1A FCGR1BP

1.92e-031731724efa0878ed1ede8fa5d6c191a76d4f70558ba761
ToppCellnormal_Lymph_Node-Myeloid_cells-CD163+CD14+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

FCGR1A FCGR1BP

1.92e-0317317238f88f5bbf92a3bf5109bc4782cd071b7cb1ca34
ToppCelldroplet-Marrow-BM-30m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.95e-03174172118ba2729ecc6aa1bb8548f3cf537b3f9e902ef0
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c6-VCAN|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

1.95e-03174172eaaf17a06efc09ed4752b449827b1f0f424d3dad
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.97e-0317517269b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

1.97e-031751724d36da7399c62c170cb603957b35a35efb2c3fbe
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.97e-031751724f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

1.97e-03175172e4c9b3c6bde390a3892b112b673f93e118220eb9
ToppCellLPS-IL1RA-Hematopoietic_Meg-Ery|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

1.97e-031751722c39c1b112e873403ad2add8595cc256bf0b97a6
ToppCell3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMB2 CASZ1

1.97e-03175172dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCellBronchial_Biopsy-Immune-Luminal_Macrophages|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

FCGR1A FCGR1BP

1.97e-031751721cf99de391552d4f8dbe2ed5b01fc3b8adca61b6
ToppCelldroplet-Marrow-nan-24m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

1.99e-03176172eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCelldroplet-Marrow-nan-21m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGR1BP TRPS1

2.01e-03177172b860013f1fd397400a62d66ab521cfc81349ffe2
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

2.04e-03178172370749834a11d981e9ede26d5f63f0ecb551c015
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery-Erythroid|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

2.04e-03178172eafacc8cd3e986d6ca309e05b6e241331a584fa5
ToppCellLPS-antiTNF-Hematopoietic_Meg-Ery|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

2.04e-031781726a5c31e976852edc7d9e899da8e2a1bf23d36759
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

2.06e-031791727329b45376a9e9a4fe34d4aa0b33af6dda0a8e3b
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

2.06e-031791726e4740f99f66d3e9348fa5057cf1030454819aa8
ToppCellLPS-IL1RA+antiTNF-Hematopoietic_Meg-Ery-Erythroid-Erythroid|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PITHD1 HYAL3

2.06e-03179172ee60ac43fb62c09967a26bbcf9306ac5ea2bdc1e
ToppCellmetastatic_Brain-Myeloid_cells-Pleural_Mac|metastatic_Brain / Location, Cell class and cell subclass

FCGR1A FCGR1BP

2.08e-031801727de1c8ab1152fa517c6b4830d93ff53a19fca3d7
ToppCellnormal_Lymph_Node-Myeloid_cells-Pleural_Mac|normal_Lymph_Node / Location, Cell class and cell subclass

FCGR1A FCGR1BP

2.10e-03181172921e917f83105896ad8918dc134b871708024021
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_monocyte_(14)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FCGR1A FCGR1BP

2.10e-031811723457c1d431db4282be5a6243119e48960748ede7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil-Neu_c6-FGF23|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

2.13e-03182172f9c013075477e77a8373c73301a51e7e3f35369c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP31 ZNF552

2.13e-03182172678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCellNS-moderate-d_07-13-Myeloid-Monocyte-derived_Macrophage|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

FCGR1A FCGR1BP

2.13e-03182172e03e995e5fd14fc6a7559b83c0ca4e7ccc8e3d0f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USP31 ZNF552

2.13e-031821728d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic-Neutrophil|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FCGR1A FCGR1BP

2.13e-031821721932d77491d6d46278f01fd70eb469ef1b356619
ToppCell3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophages-Alveolar_macrophages_L.1.0.5.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

FCGR1A NEK6

2.15e-03183172103c4c4595d8daa677679fd2fa1e99cd398e56dd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CASZ1 MYRFL

2.15e-03183172d340ab5a77e8d819a1dfb4ca3e9a4b9bc988923c
ToppCell367C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FCGR1A FCGR1BP

2.15e-0318317219cc0009f5332b6e4d4274df123eebbfc80b669a
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB CASZ1

2.15e-031831723c516fe5083f02bad1f464ed284010b4131a833c
ToppCellcellseq2-Immune-Hematopoietic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FCGR1A FCGR1BP

2.15e-03183172324ec4374b552da7ce03809945b3a0798342d4ba
ToppCellcellseq2-Immune-Hematopoietic-Granulocytic|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FCGR1A FCGR1BP

2.15e-03183172cfbf8539104cef9ca830ad4f6bb278746f7078f7
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic-Neutrophil|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

2.15e-0318317275da8c05b6d636f434c5684e0166fed0de3547b4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB CASZ1

2.15e-031831729c2689d76fc6d30f5ab093428aa669d0a98953cf
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Myeloid-Granulocytic|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGR1A FCGR1BP

2.15e-03183172340621a8e720bd98da335f90598096833681834c
ToppCell367C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FCGR1A FCGR1BP

2.15e-03183172b12b89debc9dd6396188bc8fe44f54c01c560966
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FCGR1A FCGR1BP

2.17e-03184172371c1927ac06b77ff462a94cca6acb802f9724ff
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCGR1BP HYAL3

2.17e-03184172a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FCGR1BP HYAL3

2.17e-03184172081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

FCGR1BP HYAL3

2.17e-0318417245f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Renal_corpuscle_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CBLB CASZ1

2.17e-031841727294b379ce4cb8fa75e432559082f93cd106aaf5
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FCGR1BP HYAL3

2.17e-0318417284c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FCGR1A FCGR1BP

2.17e-03184172dd6777a0cb49cd79fc439920c3c930a1e4681bb0
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid-Micro-Microglia-Micro_L1-6_C1QC|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FCGR1A FCGR1BP

2.17e-03184172fbac70333e4f028bfbdd9cc9401427caac9f0c47
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FCGR1BP HYAL3

2.17e-03184172d31d4116d1d196633784863781fa45673607a421
ToppCellPBMC-Mild-cDC_9|Mild / Compartment, Disease Groups and Clusters

FCGR1BP LAMB2

2.17e-031841722e0c9a2c40c892a2d435eafb31f1f838de9baf15
ToppCellCV-Moderate-7|Moderate / Virus stimulation, Condition and Cluster

CBLB UBR2

2.20e-03185172a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 WDR59

2.20e-0318517260206c7322b4ddb2010040aac70561df842c9843
ToppCellPrimary_Visual_cortex_(V1C)-Non-neuronal-Endothelial_Myeloid|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

FCGR1A FCGR1BP

2.20e-031851726b832b3e080dfadd21253ac45022192f4d3cb37b
ToppCellPCW_05-06-Hematologic_Myeloid-Hem_Myeloid_monocytic-im_myeloid_progenitor3_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

FCGR1A FCGR1BP

2.22e-031861726575ec6a626cdea169ffd185d47828dfaa29475d
Diseaseretinal degeneration (biomarker_via_orthology)

FCGR1A FCGR1BP

1.03e-0428162DOID:8466 (biomarker_via_orthology)
Diseasegranulocyte percentage of myeloid white cells

UBR2 TRPS1 NEK6

3.80e-04268163EFO_0007997
Diseaseeosinophil measurement

HYAL3 TRPS1

1.54e-03108162EFO_0803540
Diseasebreast carcinoma

FCGR1BP LAMB2 CASZ1 TRPS1

1.85e-031019164EFO_0000305
Diseasefacial morphology measurement

FCGR1BP CASZ1 TRPS1

1.88e-03466163EFO_0007841
Diseasephotoreceptor cell layer thickness measurement

UBR2 CASZ1

2.86e-03148162EFO_0803370
Diseaseautoimmune disease

CBLB NEK6

3.89e-03173162EFO_0005140
Diseasemonocyte count

FCGR1A CASZ1 TRPS1 NEK6

4.71e-031320164EFO_0005091
Diseasediastolic blood pressure, systolic blood pressure

CBLB CASZ1 TRPS1

5.23e-03670163EFO_0006335, EFO_0006336
DiseaseThyroid preparation use measurement

CBLB NEK6

6.04e-03217162EFO_0009933
Diseasemonocyte percentage of leukocytes

UBR2 TRPS1 NEK6

6.66e-03731163EFO_0007989

Protein segments in the cluster

PeptideGeneStartEntry
GCHLNGKSTHYHCMQ

CASZ1

541

Q86V15
SHNGTYHCSGMGKHR

FCGR1BP

161

Q92637
CDNGHCMLNGTHGPS

CBLB

736

Q13191
GMGDSCQIHGGFHSC

MYRFL

106

Q96LU7
GHMPHGGSSNNLCHT

NEK6

6

Q9HC98
KCECHGHTHSCHFDM

LAMB2

346

P55268
GDSHHSHAGGHCGGC

NAA40

221

Q86UY6
HSMHQALCPGHTGLC

GRM6

416

O15303
RAAMACSHQRCHGHG

HYAL3

351

O43820
SHNGTYHCSGMGKHR

FCGR1A

161

P12314
QHCHYCGGSGMETIN

DNAJA3

251

Q96EY1
ALHMSCHGDSGPFQC

TRPS1

1231

Q9UHF7
MSHGHSHGGGGCRCA

PITHD1

1

Q9GZP4
NFCLTCGHGGHTSHM

WDR59

936

Q6PJI9
MCCHGRQGTVHIHTS

FP248

76

Q71RG6
HGGKSHYSCGGCMKH

ZNF552

206

Q9H707
AVCNHHGTMQGGHYT

USP31

711

Q70CQ4
CGTHTSSCGHIMHAH

UBR2

1161

Q8IWV8