Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcesspositive regulation of integrin-mediated signaling pathway

FLNA LAMA2 LOXL3

1.22e-0514683GO:2001046
GeneOntologyBiologicalProcesspositive regulation of phosphate metabolic process

IL12B THBS1 ABI1 ABI3 PTPRC ABI2 PIK3R1 TBK1 RGPD1 PFKFB1 PIBF1 NOS1

2.68e-058796812GO:0045937
GeneOntologyBiologicalProcesspositive regulation of phosphorus metabolic process

IL12B THBS1 ABI1 ABI3 PTPRC ABI2 PIK3R1 TBK1 RGPD1 PFKFB1 PIBF1 NOS1

2.68e-058796812GO:0010562
GeneOntologyBiologicalProcessregulation of phosphorylation

IL12B THBS1 ABI1 ABI3 PTPRC WARS1 ABI2 PIK3R1 TBK1 RGPD1 IMPACT PIBF1 NOS1 MEN1

3.82e-0512266814GO:0042325
GeneOntologyBiologicalProcesspositive regulation of peptidyl-tyrosine phosphorylation

IL12B ABI1 ABI3 PTPRC ABI2 PIBF1

4.20e-05193686GO:0050731
GeneOntologyBiologicalProcessprotein import into nucleus

TXNIP FLNA CSE1L PIK3R1 RGPD1 SPG11

4.45e-05195686GO:0006606
GeneOntologyBiologicalProcessregulation of cell adhesion

IL12B FLNA THBS1 PTPRC GIMAP5 ZC3H8 PIK3R1 HSPH1 LAMA2 PTPN23 LOXL3 MEN1

4.51e-059276812GO:0030155
GeneOntologyBiologicalProcesspositive regulation of phosphorylation

IL12B THBS1 ABI1 ABI3 PTPRC ABI2 PIK3R1 TBK1 RGPD1 PIBF1 NOS1

4.52e-057806811GO:0042327
GeneOntologyBiologicalProcessregulation of phosphate metabolic process

IL12B THBS1 ABI1 ABI3 PTPRC WARS1 ABI2 PIK3R1 TBK1 RGPD1 IMPACT PFKFB1 PIBF1 NOS1 MEN1

4.78e-0514216815GO:0019220
GeneOntologyBiologicalProcessregulation of phosphorus metabolic process

IL12B THBS1 ABI1 ABI3 PTPRC WARS1 ABI2 PIK3R1 TBK1 RGPD1 IMPACT PFKFB1 PIBF1 NOS1 MEN1

4.85e-0514236815GO:0051174
GeneOntologyBiologicalProcessimport into nucleus

TXNIP FLNA CSE1L PIK3R1 RGPD1 SPG11

5.26e-05201686GO:0051170
GeneOntologyBiologicalProcesspositive regulation of kinase activity

IL12B THBS1 ABI1 ABI3 PTPRC ABI2 RGPD1 PIBF1

5.45e-05405688GO:0033674
GeneOntologyBiologicalProcessregulation of integrin-mediated signaling pathway

FLNA LAMA2 LOXL3

5.79e-0523683GO:2001044
GeneOntologyBiologicalProcessregulation of protein phosphorylation

IL12B THBS1 ABI1 ABI3 PTPRC WARS1 ABI2 PIK3R1 TBK1 IMPACT PIBF1 NOS1 MEN1

7.21e-0511336813GO:0001932
GeneOntologyBiologicalProcessregulation of kinase activity

IL12B THBS1 ABI1 ABI3 PTPRC WARS1 ABI2 RGPD1 PIBF1 MEN1

7.90e-056866810GO:0043549
GeneOntologyBiologicalProcessregulation of protein tyrosine kinase activity

ABI1 ABI3 PTPRC ABI2

7.95e-0569684GO:0061097
GeneOntologyBiologicalProcessregulation of alpha-beta T cell activation

IL12B PTPRC GIMAP5 HSPH1 LOXL3

1.03e-04141685GO:0046634
GeneOntologyBiologicalProcessalpha-beta T cell activation

IL12B PTPRC GIMAP5 HSPH1 LOXL3 MEN1

1.03e-04227686GO:0046631
GeneOntologyBiologicalProcesspositive regulation of protein phosphorylation

IL12B THBS1 ABI1 ABI3 PTPRC ABI2 PIK3R1 TBK1 PIBF1 NOS1

1.23e-047246810GO:0001934
GeneOntologyBiologicalProcesspositive regulation of protein kinase activity

IL12B THBS1 ABI1 ABI3 PTPRC ABI2 PIBF1

1.52e-04350687GO:0045860
GeneOntologyBiologicalProcessregulation of protein kinase activity

IL12B THBS1 ABI1 ABI3 PTPRC WARS1 ABI2 PIBF1 MEN1

1.72e-04611689GO:0045859
GeneOntologyBiologicalProcessresponse to calcium ion

TXNIP CPNE8 THBS1 CPNE9 ABCC9

1.91e-04161685GO:0051592
GeneOntologyBiologicalProcesspositive regulation of transferase activity

IL12B THBS1 ABI1 ABI3 PTPRC ABI2 RGPD1 PIBF1

2.03e-04490688GO:0051347
GeneOntologyBiologicalProcesspositive regulation of protein tyrosine kinase activity

ABI1 ABI3 ABI2

2.08e-0435683GO:0061098
GeneOntologyBiologicalProcesspositive regulation of alpha-beta T cell activation

IL12B PTPRC GIMAP5 HSPH1

2.14e-0489684GO:0046635
GeneOntologyBiologicalProcessresponse to topologically incorrect protein

THBS1 HSPA4L PIK3R1 HSPH1 UBR4

2.20e-04166685GO:0035966
GeneOntologyBiologicalProcesspositive regulation of protein modification process

IL12B THBS1 ABI1 ABI3 PTPRC MYCBP2 ABI2 PIK3R1 TBK1 PIBF1 NOS1

2.29e-049376811GO:0031401
GeneOntologyBiologicalProcessnegative regulation of cell adhesion

THBS1 PTPRC GIMAP5 ZC3H8 PIK3R1 LOXL3 MEN1

2.32e-04375687GO:0007162
GeneOntologyBiologicalProcesspositive regulation of protein metabolic process

IL12B THBS1 LARP4B ABI1 ABI3 PTPRC MYCBP2 ABI2 PIK3R1 TBK1 PIBF1 NOS1 METTL14 MEN1

2.42e-0414586814GO:0051247
GeneOntologyBiologicalProcessneuron development

FLNA MYO3A ABI1 ABI3 CPNE9 DST MYCBP2 ABI2 IMPACT LAMA2 SPG11 ATP9A MFRP NR2F1

2.51e-0414636814GO:0048666
GeneOntologyBiologicalProcessneuron projection development

FLNA MYO3A ABI1 ABI3 CPNE9 DST MYCBP2 ABI2 IMPACT LAMA2 SPG11 ATP9A NR2F1

2.53e-0412856813GO:0031175
GeneOntologyBiologicalProcessT cell differentiation

IL12B PTPRC GIMAP5 ZC3H8 PIK3R1 LOXL3 MEN1

2.60e-04382687GO:0030217
GeneOntologyBiologicalProcessregulation of peptidyl-tyrosine phosphorylation

IL12B ABI1 ABI3 PTPRC ABI2 PIBF1

2.75e-04272686GO:0050730
GeneOntologyBiologicalProcessneuron projection morphogenesis

ABI1 ABI3 CPNE9 DST MYCBP2 ABI2 IMPACT LAMA2 SPG11 ATP9A

2.82e-048026810GO:0048812
GeneOntologyBiologicalProcessregulation of membrane repolarization during cardiac muscle cell action potential

FLNA NOS1

2.96e-048682GO:1905031
GeneOntologyBiologicalProcessregulation of protein modification process

IL12B THBS1 ABI1 ABI3 PTPRC WARS1 MYCBP2 ABI2 PIK3R1 TBK1 IMPACT PIBF1 NOS1 MEN1

2.99e-0414886814GO:0031399
GeneOntologyBiologicalProcessregulation of transferase activity

IL12B THBS1 ABI1 ABI3 PTPRC WARS1 ABI2 RGPD1 PIBF1 MEN1

3.05e-048106810GO:0051338
GeneOntologyBiologicalProcesslamellipodium organization

ABI1 ABI3 ABI2 PIK3R1

3.21e-0499684GO:0097581
GeneOntologyBiologicalProcesspeptidyl-amino acid modification

IL12B MYO3A ABI1 ABI3 PTPRC ABI2 TBK1 RGPD1 LOXL3 PIBF1 NOS1

3.25e-049766811GO:0018193
GeneOntologyBiologicalProcessplasma membrane bounded cell projection morphogenesis

ABI1 ABI3 CPNE9 DST MYCBP2 ABI2 IMPACT LAMA2 SPG11 ATP9A

3.33e-048196810GO:0120039
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

FLNA MYO3A ABI3 ATP6V0D1 ABI2 PIK3R1 WDR35 PTPN23 PIBF1

3.40e-04670689GO:0120031
GeneOntologyBiologicalProcesscell projection morphogenesis

ABI1 ABI3 CPNE9 DST MYCBP2 ABI2 IMPACT LAMA2 SPG11 ATP9A

3.56e-048266810GO:0048858
GeneOntologyBiologicalProcesspositive regulation of humoral immune response mediated by circulating immunoglobulin

PTPRC GIMAP5

3.80e-049682GO:0002925
GeneOntologyBiologicalProcesscell projection assembly

FLNA MYO3A ABI3 ATP6V0D1 ABI2 PIK3R1 WDR35 PTPN23 PIBF1

3.99e-04685689GO:0030031
GeneOntologyBiologicalProcessregulation of lamellipodium assembly

ABI3 ABI2 PIK3R1

4.40e-0445683GO:0010591
GeneOntologyBiologicalProcesspositive regulation of NK T cell activation

IL12B HSPH1

4.74e-0410682GO:0051135
GeneOntologyBiologicalProcesscell morphogenesis

FLNA MYO3A ABI1 ABI3 CPNE9 DST MYCBP2 ABI2 IMPACT LAMA2 SPG11 ATP9A

4.79e-0411946812GO:0000902
GeneOntologyBiologicalProcessregulation of membrane repolarization during action potential

FLNA NOS1

5.78e-0411682GO:0098903
GeneOntologyBiologicalProcessregulation of T-helper 17 cell lineage commitment

IL12B LOXL3

5.78e-0411682GO:2000328
GeneOntologyBiologicalProcesspositive regulation of cell adhesion

IL12B FLNA THBS1 PTPRC GIMAP5 HSPH1 LAMA2 PTPN23

6.18e-04579688GO:0045785
GeneOntologyBiologicalProcessregulation of cell-cell adhesion

IL12B PTPRC GIMAP5 ZC3H8 PIK3R1 HSPH1 PTPN23 LOXL3

6.25e-04580688GO:0022407
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell differentiation

IL12B GIMAP5 LOXL3 MEN1

6.45e-04119684GO:0043367
GeneOntologyBiologicalProcesspositive regulation of gamma-delta T cell differentiation

PTPRC GIMAP5

6.92e-0412682GO:0045588
GeneOntologyBiologicalProcessregulation of NK T cell activation

IL12B HSPH1

6.92e-0412682GO:0051133
GeneOntologyBiologicalProcesspositive T cell selection

IL12B PTPRC LOXL3

7.14e-0453683GO:0043368
GeneOntologyBiologicalProcesspeptidyl-tyrosine phosphorylation

IL12B ABI1 ABI3 PTPRC ABI2 PIBF1

7.27e-04327686GO:0018108
GeneOntologyBiologicalProcesspeptidyl-tyrosine modification

IL12B ABI1 ABI3 PTPRC ABI2 PIBF1

7.50e-04329686GO:0018212
GeneOntologyBiologicalProcessintegrin-mediated signaling pathway

FLNA DST LAMA2 LOXL3

7.53e-04124684GO:0007229
GeneOntologyBiologicalProcessneuron migration

FLNA ABI1 ABI3 ABI2 NR2F1

7.65e-04218685GO:0001764
GeneOntologyBiologicalProcessnegative regulation of protein metabolic process

FLNA THBS1 PTPRC WARS1 MYCBP2 PIK3R1 IMPACT PIBF1 NOS1 CNOT1 MEN1

8.07e-0410886811GO:0051248
GeneOntologyBiologicalProcessregulation of cell activation

IL12B FLNA THBS1 PTPRC GIMAP5 ZC3H8 HSPH1 LOXL3 PIBF1

8.10e-04756689GO:0050865
GeneOntologyBiologicalProcessregulation of lamellipodium organization

ABI3 ABI2 PIK3R1

8.83e-0457683GO:1902743
GeneOntologyBiologicalProcessregulation of T cell differentiation

IL12B PTPRC GIMAP5 ZC3H8 LOXL3

8.99e-04226685GO:0045580
GeneOntologyBiologicalProcesspositive regulation of gamma-delta T cell activation

PTPRC GIMAP5

9.50e-0414682GO:0046645
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor production

IL12B THBS1 PTPRC PIK3R1

9.78e-04133684GO:0032760
GeneOntologyBiologicalProcessnegative regulation of phosphate metabolic process

PTPRC WARS1 IMPACT PFKFB1 PIBF1 NOS1 MEN1

9.84e-04478687GO:0045936
GeneOntologyBiologicalProcessnegative regulation of phosphorus metabolic process

PTPRC WARS1 IMPACT PFKFB1 PIBF1 NOS1 MEN1

1.01e-03480687GO:0010563
GeneOntologyBiologicalProcessnegative regulation of immune system process

IL12B THBS1 PTPRC GIMAP5 ZC3H8 PIK3R1 LOXL3 PIBF1

1.08e-03631688GO:0002683
GeneOntologyBiologicalProcessleukocyte cell-cell adhesion

IL12B THBS1 PTPRC GIMAP5 ZC3H8 HSPH1 LOXL3

1.08e-03486687GO:0007159
GeneOntologyBiologicalProcesspositive regulation of tumor necrosis factor superfamily cytokine production

IL12B THBS1 PTPRC PIK3R1

1.09e-03137684GO:1903557
GeneOntologyBiologicalProcessactivation of Janus kinase activity

IL12B PIBF1

1.09e-0315682GO:0042976
GeneOntologyBiologicalProcessregulation of gamma-delta T cell differentiation

PTPRC GIMAP5

1.09e-0315682GO:0045586
GeneOntologyBiologicalProcesshumoral immune response mediated by circulating immunoglobulin

PTPRC GIMAP5 CFI

1.13e-0362683GO:0002455
GeneOntologyBiologicalProcessnegative regulation of leukocyte activation

PTPRC GIMAP5 ZC3H8 LOXL3 PIBF1

1.17e-03240685GO:0002695
GeneOntologyBiologicalProcessmononuclear cell differentiation

IL12B PTPRC GIMAP5 ZC3H8 PIK3R1 LOXL3 LTBR MEN1

1.18e-03640688GO:1903131
GeneOntologyBiologicalProcesspositive regulation of extrinsic apoptotic signaling pathway

THBS1 PTPRC LTBR

1.18e-0363683GO:2001238
GeneOntologyBiologicalProcessprotein localization to nucleus

TXNIP FLNA CSE1L PIK3R1 RGPD1 SPG11

1.23e-03362686GO:0034504
GeneOntologyBiologicalProcessresponse to organophosphorus

PIK3R1 ABCC9 PYGM PFKFB1

1.25e-03142684GO:0046683
GeneOntologyBiologicalProcesscell junction organization

FLNA THBS1 ABI3 DST MYCBP2 ABI2 PIK3R1 PTPN23 ERC2 SPG11

1.27e-039746810GO:0034330
GeneOntologyBiologicalProcessregulation of gamma-delta T cell activation

PTPRC GIMAP5

1.41e-0317682GO:0046643
GeneOntologyBiologicalProcessresponse to unfolded protein

THBS1 HSPA4L PIK3R1 HSPH1

1.45e-03148684GO:0006986
GeneOntologyBiologicalProcesscell activation

IL12B FLNA THBS1 PTPRC GIMAP5 ZC3H8 PIK3R1 HSPH1 LOXL3 LTBR PIBF1 MEN1

1.46e-0313566812GO:0001775
GeneOntologyBiologicalProcessnegative regulation of protein phosphorylation

PTPRC WARS1 IMPACT PIBF1 NOS1 MEN1

1.47e-03375686GO:0001933
GeneOntologyBiologicalProcessestablishment of protein localization to organelle

TXNIP FLNA CSE1L PIK3R1 RGPD1 PTPN23 SPG11

1.51e-03515687GO:0072594
GeneOntologyBiologicalProcessnuclear transport

TXNIP FLNA CSE1L PIK3R1 RGPD1 SPG11

1.53e-03378686GO:0051169
GeneOntologyBiologicalProcessnucleocytoplasmic transport

TXNIP FLNA CSE1L PIK3R1 RGPD1 SPG11

1.53e-03378686GO:0006913
GeneOntologyBiologicalProcessT cell selection

IL12B PTPRC LOXL3

1.54e-0369683GO:0045058
GeneOntologyBiologicalProcessNK T cell activation

IL12B HSPH1

1.58e-0318682GO:0051132
GeneOntologyBiologicalProcessresponse to steroid hormone

TXNIP THBS1 PTPRC PIK3R1 PFKFB1 CNOT1

1.59e-03381686GO:0048545
GeneOntologyBiologicalProcessnegative regulation of blood pressure

PIK3R1 ABCC9 NOS1

1.60e-0370683GO:0045776
GeneOntologyBiologicalProcessleukocyte activation

IL12B THBS1 PTPRC GIMAP5 ZC3H8 PIK3R1 HSPH1 LOXL3 LTBR PIBF1 MEN1

1.62e-0311866811GO:0045321
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell activation

IL12B GIMAP5 LOXL3 MEN1

1.64e-03153684GO:0035710
GeneOntologyBiologicalProcessextrinsic apoptotic signaling pathway

THBS1 PTPRC PIK3R1 SCG2 LTBR

1.64e-03259685GO:0097191
GeneOntologyBiologicalProcessresponse to tumor cell

TXNIP IL12B ABI3

1.67e-0371683GO:0002347
GeneOntologyBiologicalProcessregulation of interleukin-12 production

IL12B THBS1 PIBF1

1.67e-0371683GO:0032655
GeneOntologyBiologicalProcessnegative regulation of cell activation

PTPRC GIMAP5 ZC3H8 LOXL3 PIBF1

1.79e-03264685GO:0050866
GeneOntologyBiologicalProcessalpha-beta T cell differentiation

IL12B GIMAP5 LOXL3 MEN1

1.80e-03157684GO:0046632
GeneOntologyBiologicalProcessinterleukin-12 production

IL12B THBS1 PIBF1

1.81e-0373683GO:0032615
GeneOntologyBiologicalProcessregulation of CD4-positive, alpha-beta T cell differentiation

IL12B GIMAP5 LOXL3

1.81e-0373683GO:0043370
GeneOntologyBiologicalProcessregulation of lymphocyte differentiation

IL12B PTPRC GIMAP5 ZC3H8 LOXL3

1.85e-03266685GO:0045619
GeneOntologyCellularComponentSCAR complex

ABI1 ABI3 ABI2

7.74e-0612703GO:0031209
GeneOntologyCellularComponentfilopodium tip

MYO3A ABI1 ABI2

3.94e-0520703GO:0032433
MousePhenoabnormal NK T cell morphology

TXNIP PTPRC GIMAP5 PIK3R1 TBK1 LTBR

4.62e-06107576MP:0008036
MousePhenoabnormal NK T cell number

TXNIP PTPRC GIMAP5 PIK3R1 TBK1 LTBR

4.62e-06107576MP:0008038
MousePhenodecreased NK T cell number

TXNIP PTPRC GIMAP5 PIK3R1 TBK1

1.22e-0574575MP:0008040
MousePhenoincreased skeletal muscle cell glucose uptake

TXNIP PIK3R1 ABCC9

1.38e-0512573MP:0031619
MousePhenohypoglycemia

TXNIP ARV1 PIK3R1 ABCC9 MEN1

7.97e-05109575MP:0000189
MousePhenodecreased circulating glucose level

TXNIP PHKB ARV1 PIK3R1 IMPACT SCUBE3 ABCC9 MFRP NT5DC3 MIER1 MEN1

9.14e-056915711MP:0005560
MousePhenoincreased insulin sensitivity

TXNIP ARV1 PIK3R1 IMPACT ABCC9 MFRP

1.12e-04188576MP:0002891
MousePhenoabnormal liver morphology

TXNIP PHKB FLNA THBS1 WARS1 ARV1 GIMAP5 ZC3H8 PIK3R1 TBK1 RGPD1 TMEM63C MFRP NOS1 PCTP MEN1

1.34e-0414335716MP:0000598
MousePhenoabnormal esophagus morphology

THBS1 KRT15 WDR35 NOS1

1.48e-0466574MP:0000467
MousePhenoabnormal effector T cell number

TXNIP PTPRC GIMAP5 PIK3R1 TBK1 LTBR

1.71e-04203576MP:0013762
MousePhenoabnormal hepatobiliary system morphology

TXNIP PHKB FLNA THBS1 WARS1 ARV1 GIMAP5 ZC3H8 PIK3R1 TBK1 RGPD1 TMEM63C MFRP NOS1 PCTP MEN1

1.90e-0414765716MP:0002138
MousePhenoincreased muscle cell glucose uptake

TXNIP PIK3R1 ABCC9

2.18e-0429573MP:0030021
MousePhenoliver degeneration

TXNIP GIMAP5 TBK1

2.66e-0431573MP:0003103
DomainAbl-interactor_HHR_dom

ABI1 ABI3 ABI2

4.83e-083693IPR012849
DomainAbi_HHR

ABI1 ABI3 ABI2

4.83e-083693PF07815
DomainABI

ABI3 ABI2

1.35e-052692IPR028457
DomainSH3_1

ABI1 ABI3 DST ABI2 PIK3R1

3.51e-04164695PF00018
DomainCopine

CPNE8 CPNE9

4.76e-049692PF07002
DomainCopine

CPNE8 CPNE9

4.76e-049692IPR010734
DomainFilamin

FLNA MYCBP2

7.24e-0411692PF00630
DomainFILAMIN_REPEAT

FLNA MYCBP2

7.24e-0411692PS50194
DomainFilamin/ABP280_rpt

FLNA MYCBP2

7.24e-0411692IPR001298
DomainFilamin/ABP280_repeat-like

FLNA MYCBP2

7.24e-0411692IPR017868
Domain-

HSPA4L HSPH1

8.67e-04126922.60.34.10
DomainHSP70_peptide-bd

HSPA4L HSPH1

8.67e-0412692IPR029047
Domain-

HSPA4L HSPH1

1.02e-03136921.20.1270.10
DomainHeat_shock_70_CS

HSPA4L HSPH1

1.02e-0313692IPR018181
DomainHSP70_C

HSPA4L HSPH1

1.02e-0313692IPR029048
DomainSH3

ABI1 ABI3 DST ABI2 PIK3R1

1.22e-03216695PS50002
DomainSH3_domain

ABI1 ABI3 DST ABI2 PIK3R1

1.32e-03220695IPR001452
DomainHSP70

HSPA4L HSPH1

1.56e-0316692PF00012
DomainHSP70_2

HSPA4L HSPH1

1.76e-0317692PS00329
DomainHSP70_3

HSPA4L HSPH1

1.76e-0317692PS01036
DomainHSP70_1

HSPA4L HSPH1

1.76e-0317692PS00297
DomainHsp_70_fam

HSPA4L HSPH1

1.98e-0318692IPR013126
DomainSRCR

LOXL3 CFI

2.70e-0321692PF00530
DomainActinin_actin-bd_CS

FLNA DST

3.24e-0323692IPR001589
DomainACTININ_2

FLNA DST

3.24e-0323692PS00020
DomainACTININ_1

FLNA DST

3.24e-0323692PS00019
DomainSR

LOXL3 CFI

3.82e-0325692SM00202
Domain-

LOXL3 CFI

3.82e-03256923.10.250.10
DomainSRCR_1

LOXL3 CFI

4.13e-0326692PS00420
DomainSRCR_2

LOXL3 CFI

4.13e-0326692PS50287
DomainT_SNARE

ABI1 ABI2

4.13e-0326692PS50192
DomainSRCR-like_dom

LOXL3 CFI

4.13e-0326692IPR017448
DomainSRCR

LOXL3 CFI

4.45e-0327692IPR001190
DomainT_SNARE_dom

ABI1 ABI2

5.12e-0329692IPR000727
DomainIg_E-set

TXNIP FLNA MYCBP2

6.73e-03104693IPR014756
Pubmed

In search of a function for the E3B1/Abi2/Argbp1/NESH family (Review).

ABI1 ABI3 ABI2

7.81e-09370312011975
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

SRRT LARP4B ABI1 CSE1L KRT15 WARS1 SF3B6 UBR4 RGPD1 PTPN23 CNOT1

8.95e-08665701130457570
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

PHKB SRRT FLNA ABI1 ATP6V0D1 CSE1L DST WARS1 HSPA4L HSPH1 ERC2 ATP9A NT5DC3 NOS1 CNOT1

1.31e-071431701537142655
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

PHKB FLNA LARP4B PTPRC WARS1 PIK3R1 INPP5B HSPH1 PTPN23 CNOT1 MIER1 METTL14 MEN1

2.23e-071084701311544199
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

FLNA LARP4B ABI1 ATP6V0D1 CSE1L WARS1 MYCBP2 ABI2 UBR4 RGPD1 NT5DC3 NOS1 CNOT1

3.91e-071139701336417873
Pubmed

NESH (Abi-3) is present in the Abi/WAVE complex but does not promote c-Abl-mediated phosphorylation.

ABI1 ABI3 ABI2

9.28e-071070317101133
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

FLNA MYO3A CPNE8 CPNE9 CSE1L DST TBK1 HSPH1 UBR4 RGPD1 PYGM

9.46e-07844701125963833
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

PHKB CPNE8 ABI2 TBK1 HSPH1 RGPD1 PTPN23 PIBF1 CFI CNOT1 MEN1

1.05e-06853701128718761
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

TXNIP FLNA DST MYCBP2 TBK1 UBR4 RGPD1 CNOT1

2.01e-0641870834709266
Pubmed

Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling.

ABI1 ABI2

3.99e-06270216401422
Pubmed

The Abl interactor proteins localize to sites of actin polymerization at the tips of lamellipodia and filopodia.

ABI1 ABI2

3.99e-06270211516653
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

SRRT FLNA CPNE8 THBS1 LARP4B CSE1L KRT15 DST FAM83F HSPH1 PRSS23 METTL14

7.23e-061257701236526897
Pubmed

Extracellular matrix secretion by cardiac fibroblasts: role of microRNA-29b and microRNA-30c.

THBS1 LAMA2 LOXL3 PRSS23 MFRP CFI

1.11e-0524870624006456
Pubmed

Regulation of cell-cell adhesion by Abi/Diaphanous complexes.

ABI1 ABI2

1.20e-05370219158278
Pubmed

Biochemical characterization of copine: a ubiquitous Ca2+-dependent, phospholipid-binding protein.

CPNE8 CPNE9

1.20e-05370211123945
Pubmed

METTL14 drives growth and metastasis of non-small cell lung cancer by regulating pri-miR-93-5p maturation and TXNIP expression.

TXNIP METTL14

1.20e-05370237594665
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

PHKB FLNA ABI1 CSE1L DST WARS1 MYCBP2 HSPA4L HSPH1 UBR4 CNOT1

1.77e-051149701135446349
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

ABI1 DST MYCBP2 ABI2 TBK1 UBR4 RGPD1 ERC2 NOS1 CNOT1

2.23e-05963701028671696
Pubmed

Abl interactor 1 (Abi-1) wave-binding and SNARE domains regulate its nucleocytoplasmic shuttling, lamellipodium localization, and wave-1 levels.

ABI1 ABI2

2.39e-05470215143189
Pubmed

Localization and phosphorylation of Abl-interactor proteins, Abi-1 and Abi-2, in the developing nervous system.

ABI1 ABI2

2.39e-05470210995551
Pubmed

A functional 14-3-3zeta-independent association of PI3-kinase with glycoprotein Ib alpha, the major ligand-binding subunit of the platelet glycoprotein Ib-IX-V complex.

FLNA PIK3R1

2.39e-05470218299448
Pubmed

The NESH/Abi-3-based WAVE2 complex is functionally distinct from the Abi-1-based WAVE2 complex.

ABI1 ABI3

2.39e-05470226428302
Pubmed

Potent intestinal Th17 priming through peripheral lipopolysaccharide-based immunization.

IL12B PTPRC

2.39e-05470220130220
Pubmed

Network organization of the huntingtin proteomic interactome in mammalian brain.

CPNE8 ATP6V0D1 DST HSPH1 ERC2 ABCC9 PYGM NOS1

3.52e-0562170822794259
Pubmed

Forced expression of NESH suppresses motility and metastatic dissemination of malignant cells.

ABI1 ABI3

3.98e-05570211956071
Pubmed

Phosphoinositide 3-kinase activates Rac by entering in a complex with Eps8, Abi1, and Sos-1.

ABI1 PIK3R1

3.98e-05570212515821
Pubmed

ABI2-deficient mice exhibit defective cell migration, aberrant dendritic spine morphogenesis, and deficits in learning and memory.

ABI1 ABI2

3.98e-05570215572692
Pubmed

Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.

ABI1 ABI2

3.98e-05570221173240
Pubmed

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.

FLNA TBK1 LTBR MIER1

4.00e-059470412761501
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SRRT LARP4B ABI1 ATP6V0D1 DST ABI2 SF3B6 HSPH1 ATP9A COMTD1 METTL14 MEN1

4.07e-051497701231527615
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

PHKB DST MYCBP2 TBK1 PIBF1 CNOT1 MIER1 MEN1

4.60e-0564570825281560
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

FLNA CSE1L DST HSPH1 UBR4 LTBR

4.79e-0532270626514267
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNA LARP4B CSE1L DST WARS1 MYCBP2 UBR4 CNOT1

5.02e-0565370822586326
Pubmed

A human MAP kinase interactome.

FLNA CSE1L KRT15 DST PIK3R1 PTPN23 PIBF1

5.59e-0548670720936779
Pubmed

LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.

PHKB FLNA CPNE8 THBS1 CNOT1

5.60e-0520270533005030
Pubmed

Noncanonical STAT1 phosphorylation expands its transcriptional activity into promoting LPS-induced IL-6 and IL-12p40 production.

IL12B TBK1

5.96e-05670232209697
Pubmed

A TRAF-like motif of the inducible costimulator ICOS controls development of germinal center TFH cells via the kinase TBK1.

PIK3R1 TBK1

5.96e-05670227135603
Pubmed

A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.

LARP4B ABI1 DST MYCBP2 TBK1 LAMA2 PYGM

6.43e-0549770723414517
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

PHKB FLNA CSE1L HSPA4L HSPH1 UBR4

6.90e-0534470630333137
Pubmed

Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.

ABI1 DST MYCBP2 HSPA4L HSPH1 ERC2

7.24e-0534770617114649
Pubmed

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

KRT15 WARS1 HSPA4L ERC2

7.40e-0511070427889896
Pubmed

Fat3 acts through independent cytoskeletal effectors to coordinate asymmetric cell behaviors during polarized circuit assembly.

ABI1 ABI2

8.33e-05770235108541
Pubmed

A novel HSF1-mediated death pathway that is suppressed by heat shock proteins.

HSPA4L HSPH1

8.33e-05770217024176
Pubmed

DAMP-Inducing Adjuvant and PAMP Adjuvants Parallelly Enhance Protective Type-2 and Type-1 Immune Responses to Influenza Split Vaccination.

IL12B TBK1

8.33e-05770230515151
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

DST MYCBP2 WDR35 PTPN23 ERC2

9.32e-0522570512168954
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

SRRT FLNA CPNE8 ATP6V0D1 TBK1 SF3B6 HSPH1 WDR35 NR2F1

9.51e-0592270927609421
Pubmed

Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.

SRRT FLNA LARP4B HSPH1 UBR4 CNOT1 MEN1

1.01e-0453470735032548
Pubmed

Spatacsin regulates directionality of lysosome trafficking by promoting the degradation of its partner AP5Z1.

UBR4 SPG11

1.11e-04870237871017
Pubmed

Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.

PTPRC PIK3R1

1.11e-04870217846664
Pubmed

Caveolin-3 deficiency causes muscle degeneration in mice.

LAMA2 NOS1

1.11e-04870211115849
Pubmed

Structure and control of the actin regulatory WAVE complex.

ABI1 ABI2

1.11e-04870221107423
Pubmed

Defining the membrane proteome of NK cells.

GDPD1 FLNA LARP4B ABI3 CSE1L PTPRC MYCBP2 PIK3R1 UBR4 CNOT1

1.12e-041168701019946888
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

FLNA LARP4B CSE1L HSPA4L TBK1 HSPH1 UBR4 ATP9A NR2F1

1.12e-0494270931073040
Pubmed

Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.

PHKB SRRT FLNA LARP4B HSPA4L HSPH1 UBR4

1.22e-0455170734728620
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

SRRT FLNA ATP6V0D1 CSE1L WARS1 HSPA4L TBK1 HSPH1 UBR4 SPATA18 CNOT1

1.23e-041425701130948266
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

FLNA KRT15 DST HSPA4L HSPH1 UBR4 RGPD1 ERC2 SPG11 STK31 MEN1

1.37e-041442701135575683
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

THBS1 WARS1 ARV1 MYCBP2 HSPA4L HSPH1 SEL1L3 LTBR PRSS23 ATP9A

1.40e-041201701035696571
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

FLNA THBS1 CSE1L KRT15 HSPH1 WDR35 ERC2

1.41e-0456470721565611
Pubmed

The copines, a novel class of C2 domain-containing, calcium-dependent, phospholipid-binding proteins conserved from Paramecium to humans.

CPNE8 CPNE9

1.42e-0497029430674
Pubmed

Mammalian Polycomb complexes are required for Peyer's patch development by regulating lymphoid cell proliferation.

PTPRC LTBR

1.42e-04970216815646
Pubmed

Genetic modifiers of muscular dystrophy: implications for therapy.

LAMA2 NOS1

1.42e-04970216916601
Pubmed

The multi-subunit GID/CTLH E3 ubiquitin ligase promotes cell proliferation and targets the transcription factor Hbp1 for degradation.

LARP4B HSPA4L HSPH1 UBR4 CNOT1

1.61e-0425370529911972
Pubmed

Progressive aggregation despite chaperone associations of a mutant SOD1-YFP in transgenic mice that develop ALS.

HSPA4L HSPH1

1.78e-041070219171884
Pubmed

Real-time resolution of point mutations that cause phenovariance in mice.

PTPRC LTBR

1.78e-041070225605905
Pubmed

Genome-wide association study for serum urate concentrations and gout among African Americans identifies genomic risk loci and a novel URAT1 loss-of-function allele.

PYGM MEN1

1.78e-041070221768215
Pubmed

Gene expression in the developing mouse retina by EST sequencing and microarray analysis.

DST INPP5B PRSS23 METTL14

1.98e-0414270411812828
Pubmed

Loss of C9ORF72 impairs autophagy and synergizes with polyQ Ataxin-2 to induce motor neuron dysfunction and cell death.

TBK1 UBR4 WDR35

2.01e-045670327103069
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

SRRT FLNA CPNE8 CSE1L DST MYCBP2 TBK1 SF3B6 CNOT1

2.09e-04102470924711643
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

TBK1 UBR4 IMPACT PTPN23 PRSS23 NR2F1 BRAP

2.14e-0460470738803224
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

FLNA CSE1L DST WARS1 MYCBP2 HSPH1 UBR4 CNOT1

2.15e-0480770830575818
Pubmed

Abi1/Hssh3bp1 pY213 links Abl kinase signaling to p85 regulatory subunit of PI-3 kinase in regulation of macropinocytosis in LNCaP cells.

ABI1 PIK3R1

2.17e-041170220598684
Pubmed

Absence of Nkx2-3 homeodomain transcription factor induces the formation of LYVE-1-positive endothelial cysts without lymphatic commitment in the spleen.

PTPRC LTBR

2.17e-041170221705651
Pubmed

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition.

LARP4B HSPA4L PIK3R1 HSPH1

2.32e-0414870435676246
Pubmed

mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.

SRRT FLNA LARP4B HSPA4L HSPH1

2.33e-0427470534244482
Pubmed

Global phosphoproteome of HT-29 human colon adenocarcinoma cells.

WARS1 HSPH1 PYGM

2.34e-045970316083285
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PHKB CSE1L PTPRC MYCBP2 ABI2 PIK3R1 PTPN23 PIBF1 CNOT1

2.49e-04104970927880917
Pubmed

Respiratory distress and early neonatal lethality in Hspa4l/Hspa4 double-mutant mice.

HSPA4L HSPH1

2.60e-041270223980576
Pubmed

Heat-shock protein HSPA4 is required for progression of spermatogenesis.

HSPA4L HSPH1

2.60e-041270221487003
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

FLNA ATP6V0D1 DST WARS1 MYCBP2 TBK1 HSPH1 UBR4 PTPN23 CNOT1

2.61e-041297701033545068
Pubmed

Physiological and pathophysiological characteristics of ataxin-3 isoforms.

FLNA CSE1L HSPA4L SF3B6 HSPH1

2.62e-0428170530455355
Pubmed

Virus-Host Interactome and Proteomic Survey Reveal Potential Virulence Factors Influencing SARS-CoV-2 Pathogenesis.

CSE1L MYCBP2 HSPA4L TBK1 PIBF1

2.79e-0428570532838362
Pubmed

Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord.

SEL1L3 ERC2 ATP9A CNOT1

2.84e-0415670422008794
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

FLNA CSE1L HSPA4L HSPH1 UBR4 PTPN23 CNOT1

2.98e-0463870733239621
Pubmed

K63 ubiquitylation triggers proteasomal degradation by seeding branched ubiquitin chains.

TXNIP HSPA4L UBR4

3.12e-046570329378950
Pubmed

LTbetaR signaling induces cytokine expression and up-regulates lymphangiogenic factors in lymph node anlagen.

PTPRC LTBR

3.58e-041470219380791
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

SRRT FLNA CSE1L DST WARS1 MYCBP2 SF3B6 HSPH1 UBR4 PTPN23

3.64e-041353701029467282
Pubmed

Proximity interactions of the ubiquitin ligase Mind bomb 1 reveal a role in regulation of epithelial polarity complex proteins.

TBK1 PIBF1 CNOT1 BRAP

3.84e-0416970431462741
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

PHKB SRRT THBS1 ABI3 HSPA4L UBR4

3.94e-0447570631040226
Pubmed

HIV-1 gp120-mediated apoptosis of T cells is regulated by the membrane tyrosine phosphatase CD45.

PTPRC PIK3R1

4.71e-041670216524887
Pubmed

Accessory protein-like is essential for IL-18-mediated signaling.

IL12B PTPRC

4.71e-041670215843532
Pubmed

Systematic protein-protein interaction mapping for clinically relevant human GPCRs.

SRRT ABI3 ATP6V0D1 DST ARV1 UBR4 ATP9A

5.06e-0469770728298427
Pubmed

CYLD Regulates Centriolar Satellites Proteostasis by Counteracting the E3 Ligase MIB1.

THBS1 CSE1L UBR4 PIBF1

5.08e-0418270431067453
Pubmed

Bioinformatics and cellular signaling.

FLNA ABI1 PIK3R1 LTBR

5.08e-0418270415102471
Pubmed

A subset of cerebrovascular pericytes originates from mature macrophages in the very early phase of vascular development in CNS.

PTPRC ABCC9

5.33e-041770228634350
Pubmed

TNFα-dependent development of lymphoid tissue in the absence of RORγt⁺ lymphoid tissue inducer cells.

PTPRC LTBR

5.33e-041770224129162
Pubmed

Human transcription factor protein interaction networks.

SRRT LARP4B CSE1L DST HSPA4L HSPH1 UBR4 RGPD1 CNOT1 MIER1

5.59e-041429701035140242
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

FLNA CPNE8 LARP4B ATP6V0D1 CSE1L DST HSPA4L HSPH1 UBR4 CNOT1

5.93e-041440701030833792
Pubmed

SARS-CoV-2 ORF8 Protein Induces Endoplasmic Reticulum Stress-like Responses and Facilitates Virus Replication by Triggering Calnexin: an Unbiased Study.

FLNA UBR4

5.98e-041870236877072
Pubmed

Fate mapping and scRNA sequencing reveal origin and diversity of lymph node stromal precursors.

PTPRC LTBR

5.98e-041870235358427
Pubmed

Lymphatic Endothelial Cells Control Initiation of Lymph Node Organogenesis.

PTPRC LTBR

5.98e-041870228709801
InteractionDTNB interactions

ABI1 ABI3 KRT15 ABI2 NOS1 CCDC136

1.38e-06101706int:DTNB
InteractionNCKAP1 interactions

FLNA ABI1 ABI2 PIK3R1 HSPH1 SPG11 METTL14

1.06e-05218707int:NCKAP1
InteractionMCM2 interactions

SRRT FLNA MYO3A CPNE8 CPNE9 CSE1L DST TBK1 HSPH1 UBR4 RGPD1 PYGM CNOT1 MEN1

1.73e-0510817014int:MCM2
InteractionITGB3 interactions

FLNA THBS1 CSE1L HSPA4L HSPH1 UBR4

2.77e-05170706int:ITGB3
InteractionIQCB1 interactions

FLNA THBS1 CSE1L KRT15 HSPH1 WDR35 ERC2 LTBR

4.19e-05370708int:IQCB1
InteractionATXN1 interactions

SRRT LARP4B ABI1 ATP6V0D1 CSE1L KRT15 WARS1 SF3B6 UBR4 PTPN23 STK31 CNOT1 CCDC136

5.17e-0510397013int:ATXN1
GeneFamilyCopines

CPNE8 CPNE9

1.70e-049402829
GeneFamilyHeat shock 70kDa proteins

HSPA4L HSPH1

6.36e-0417402583
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

TXNIP FLNA CRYBG2 PTPRC LAMA2 PRSS23

4.55e-07184706791f1bcb954aadc63d4117c400537d036f68734d
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 PIK3R1 LAMA2 ABCC9 PRSS23 NR2F1

6.20e-07194706240d122dcb9dd1ab2867503ad85869853adcacae
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 PIK3R1 LAMA2 ABCC9 PRSS23 NR2F1

6.20e-07194706ae7df037592f1c20c9d32be15fe6fc3c562ebeb1
ToppCell10x5'-bone_marrow-Lymphocytic_T_CD8-Tem/emra_CD8|bone_marrow / Manually curated celltypes from each tissue

SRRT FLNA ABI3 PTPRC PIK3R1 PRSS23

6.58e-07196706f23c33ad10f933250be98e8389a9aa278e876f96
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

TXNIP FLNA PTPRC PIK3R1 SPG11 PRSS23

6.78e-07197706836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_vein|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CPNE8 ABI3 DST LCTL PRSS23

7.41e-061717053112d15f2a28cf4a71992db4971d960716dc1264
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

CPNE9 SEL1L3 ERC2 NT5DC3 CCDC136

8.52e-06176705d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SRRT FLNA HSPH1 TMEM63C MEN1

8.76e-0617770584930899eb2978598bc8a351cbcd9e714e46799d
ToppCellE18.5-samps-Mesenchymal-Pericyte|E18.5-samps / Age Group, Lineage, Cell class and subclass

LAMA2 ABCC9 LOXL3 PRSS23 NR2F1

9.51e-061807050b1d370db64862fe1c7ea0ffaf06d03ec82e6e70
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 LAMA2 ABCC9 PRSS23 NR2F1

1.00e-0518270544764676ed3f51ba171ce63f669390392fa50a43
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 LAMA2 ABCC9 PRSS23 NR2F1

1.00e-05182705d82f59a3f930a840dde27dc6ab024f227a26d446
ToppCellSubstantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

ATP6V0D1 MYCBP2 SCG2 IMPACT ERC2

1.17e-05188705b73e8a40393c3f656e2fcfe395a761b1f985c254
ToppCellBL-critical-LOC-Epithelial-Basal|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

KRT15 DST ABCC9 PRSS23 CFI

1.36e-051947052932f704656ca368565ec12f3452af3b18e8df12
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 DST LAMA2 ABCC9 PRSS23

1.36e-0519470590efdbd7f1c85fd7fd622b10340250b1d8fc1197
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 DST LAMA2 ABCC9 PRSS23

1.36e-05194705df82cce5ebeb73740b02cf816c6df82253cfd566
ToppCellfacs-Thymus-Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE8 KRT15 DST SCG2 PRSS23

1.36e-05194705255d6eead8da740a942a5e7d554dbd895d736d1a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 DST LAMA2 ABCC9 NR2F1

1.40e-05195705d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellT/NK_cells-CD8+_Naive_T_cell|World / Lineage and Cell class

FLNA ABI3 PTPRC PIK3R1 PRSS23

1.40e-0519570543f11068beea076e9caeb1572215c3f65c9308e1
ToppCellfacs-Thymus-Epithelium-24m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPNE8 KRT15 DST SCG2 PRSS23

1.40e-05195705cc89261bb091ef978bd73cffc68ccdd00a8786d1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA LAMA2 ABCC9 PRSS23 NR2F1

1.40e-05195705edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellmetastatic_Lymph_Node-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

TXNIP FLNA ABI3 PTPRC PRSS23

1.40e-05195705bff726515ea9ce82c223e6c805000afe2e9b7206
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THBS1 LAMA2 ABCC9 PRSS23 NR2F1

1.40e-0519570544d7bef5f59c2c2bad1392ee6aabdaa5d7f531d9
ToppCellCOVID-19_Severe-Lymphoid_T/NK-gd_T|COVID-19_Severe / Disease group, lineage and cell class

TXNIP FLNA PTPRC LAMA2 PRSS23

1.40e-051957059990440bda7fac5d00ef80444fab07459be625e1
ToppCellfacs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNIP DST HSPA4L PIK3R1 PCTP

1.43e-0519670590edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TXNIP FLNA PTPRC LAMA2 PRSS23

1.43e-05196705418e8e0a51c5cb60e3b903e7d2d800dc8b9f3d5c
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA LAMA2 ABCC9 PRSS23 NR2F1

1.43e-05196705fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TXNIP FLNA PTPRC LAMA2 PRSS23

1.43e-05196705581fc8c8d42005aacd7b401a2c9d1fc331fb4af7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

FLNA LAMA2 ABCC9 PRSS23 NR2F1

1.43e-05196705802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TXNIP FLNA PTPRC LAMA2 PRSS23

1.43e-051967056beaf0c2799424c59819b286fbb5c1a83d85e4d1
ToppCellPBMC-Severe-Lymphocyte-T/NK-Other_T-gd_T|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TXNIP FLNA PTPRC LAMA2 PRSS23

1.43e-05196705c35f2349dfe35baa845f790b9f31673dceac54c0
ToppCell10x5'-blood-Lymphocytic_T_CD8|blood / Manually curated celltypes from each tissue

SRRT ABI3 PTPRC PIK3R1 PRSS23

1.43e-051967052bf0f36af1d0934c03999dbbff3c51ae9432386d
ToppCellBronchial_Biopsy-Epithelial-Basal_1|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

FLNA KRT15 DST PIK3R1 PRSS23

1.47e-05197705a4855c5aebea4f0fed4eb035844572e82e5bac46
ToppCell(5)_Fibroblasts-(5)_Fibroblast-E|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

TXNIP PIK3R1 LAMA2 ABCC9 CFI

1.47e-051977059b1c1d72c5a8c90d71ae31e4c198d2276872eaa0
ToppCellBronchial_Biopsy-Epithelial-Basal_1|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

FLNA KRT15 DST PIK3R1 PRSS23

1.47e-0519770561c1c29a62d4c033999b7f0183c1e9cdd6a62925
ToppCellT_cells-CTLs|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

FLNA ABI3 PTPRC SPG11 PRSS23

1.47e-0519770528117cf300e169182571fbad0de1681a484a435a
ToppCell10x5'-blood-Lymphocytic_T_CD8-Tem/emra_CD8|blood / Manually curated celltypes from each tissue

SRRT ABI3 PTPRC PIK3R1 PRSS23

1.47e-0519770513e6611cde9364f0c1bf681b0b26c4d2725e5f4a
ToppCellCOVID_vent-Lymphocytic-T_cell-CD8+_Memory_T_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

TXNIP FLNA PTPRC PIK3R1 PRSS23

1.47e-05197705d4dfb3b561d0783cdbee4e8d27009ad81df695cb
ToppCellCOVID_vent-Lymphocytic-ILC|COVID_vent / Disease condition, Lineage, Cell class and subclass

TXNIP FLNA ABI3 PTPRC PRSS23

1.54e-05199705e3ff7fa1b1de1aaf6b46cdf49afa95bad457728a
ToppCellCOVID-19_Moderate-CD8+_Tem|COVID-19_Moderate / disease group, cell group and cell class

TXNIP FLNA PTPRC PIK3R1 PRSS23

1.54e-05199705adcaf9bd73933259dcf7983ca369a98e2f312d0b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

FLNA DST PIK3R1 LAMA2 PRSS23

1.54e-0519970538cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellCOVID_vent-Lymphocytic-ILC-NK_cell|COVID_vent / Disease condition, Lineage, Cell class and subclass

TXNIP FLNA ABI3 PTPRC PRSS23

1.54e-051997055f914962e2572b0c6372465b81b7496fa663d93c
ToppCellsevere-gd_T|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TXNIP FLNA PTPRC PIK3R1 PRSS23

1.54e-05199705e5a17a9f8f3be05d6abe1116607d17633df3c7ef
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

THBS1 DST LAMA2 ABCC9 NR2F1

1.54e-051997059503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellCOVID-19_Moderate-CD4+_CTL|COVID-19_Moderate / disease group, cell group and cell class

TXNIP FLNA PTPRC PIK3R1 PRSS23

1.58e-05200705a9c73559e2c9fda1b065bfb5ce84978995505924
ToppCellsevere-CD8+_Tem|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TXNIP FLNA PTPRC PIK3R1 PRSS23

1.58e-05200705aaa2cd326dc15dee2fd975ca133359c5826f6a75
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

TXNIP FLNA PTPRC GIMAP5 PRSS23

1.58e-052007052281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellsevere-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TXNIP FLNA PTPRC PIK3R1 PRSS23

1.58e-052007056aa77955017d073a96324e4db6b9950a2ec46cf8
ToppCellCOVID-19|World / Disease, condition lineage and cell class

FLNA MYCBP2 PIK3R1 CNOT1 MIER1

1.58e-052007057dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCellCOVID-19-COVID-19_Severe-Lymphocyte-T/NK-gd_T|COVID-19_Severe / Disease, condition lineage and cell class

TXNIP FLNA PTPRC LAMA2 PRSS23

1.58e-05200705f72bc3f6606ae77fe1b0a972e35b3ce0727804d9
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal-Interneuron|GW10 / Sample Type, Dataset, Time_group, and Cell type.

CPNE8 HSPA4L SCUBE3 ERC2

4.66e-05126704ec445ec097c9c45cd47b8cfa8c140df5b298695e
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 ERC2 ABCC9 NR2F1

1.07e-041567046365b69ede98bc866e996bc52736b00401aacf6f
ToppCellLPS-antiTNF-Stromal_mesenchymal-Myocytic-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 ERC2 ABCC9 NR2F1

1.09e-04157704bfec34182f052cf1c0d847ba53ea335d4d1190de
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

TXNIP ABI3 PTPRC ABCC9

1.15e-04159704bf8ff9251bcb64b2b9d6dd93461aec97659686ec
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ABI3 TMEM63C SCUBE3 PRSS23

1.18e-04160704955acb023ce4ccfac5073c9d693db87db3856187
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ABI2 LAMA2 LOXL3 NR2F1

1.21e-0416170482ed45f144a07856fe92d37426c5f92e259a03a9
ToppCellfacs-Thymus-Thymus_Flowthrough-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 PTPRC GIMAP5 MIER1

1.23e-041627047e6d20704d77b28512690f882f9ddbbd9c5c3228
ToppCellfacs-Thymus-Thymus_Flowthrough|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABI3 PTPRC GIMAP5 MIER1

1.23e-041627042c193f766f2cefe67682f34325d1de6aed778f49
ToppCelltumor_Lung-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

FLNA ABI3 PIK3R1 PRSS23

1.29e-0416470460fe6bb86afaebd92590135f08f5434ce0d8d73c
ToppCellBasal_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

CRYBG2 KRT15 FAM83F NT5DC3

1.36e-04166704aea2ae12e4746149ebc6da063ef694381c098f80
ToppCell368C-Lymphocytic-ILC|368C / Donor, Lineage, Cell class and subclass (all cells)

HSPA4L GIMAP5 PIK3R1 WDR35

1.52e-041717043b3143e4aa6520ee9c6b6f2482206ad3d8205d14
ToppCell368C-Lymphocytic-ILC-ILC-2|368C / Donor, Lineage, Cell class and subclass (all cells)

HSPA4L GIMAP5 PIK3R1 WDR35

1.52e-04171704fd01076574dcc82bfd4a1538812500543b16794f
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

CRYBG2 PRSS23 CFI NR2F1

1.55e-041727040be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellE16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TXNIP CPNE8 DST GIMAP5

1.55e-041727049a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCellnormal_Pleural_Fluid-T/NK_cells-Cytotoxic_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

FLNA ABI3 TMEM63C PRSS23

1.59e-041737041e8a43ff32eab95857c794e0bf4f0b0dba155b4a
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Natural_Killer_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC GIMAP5 PIK3R1 CCDC136

1.62e-041747045b00a795a9dd1a77305fcac5017cb276afdc1a27
ToppCelldroplet-Lung-nan-18m-Lymphocytic-mature_NK_T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRC GIMAP5 PIK3R1 CCDC136

1.62e-041747043340b44c77f55244e3c2e2ea479d42563f937040
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DST PIK3R1 LAMA2 NR2F1

1.66e-041757041799a7be623dc3bf53ba580a7c47d2619969d708
ToppCell356C-Myeloid-Dendritic-cDC_proliferating_2|Dendritic / Donor, Lineage, Cell class and subclass (all cells)

CPNE9 CSE1L LCTL NR2F1

1.66e-041757047de1023161233b64f11e130881c742f4cf2bff65
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

CRYBG2 ABI1 MYCBP2 HSPA4L

1.66e-041757040cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellCOVID-19_Severe-CD4+_CTL|COVID-19_Severe / disease group, cell group and cell class

TXNIP PTPRC LAMA2 PRSS23

1.73e-0417770434e9455790bae905dd91923792f4109d18b7686e
ToppCell356C-Lymphocytic-NK_cells-NK_cell_C|356C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP ABI3 PTPRC PRSS23

1.77e-041787047203149864cc8d5ae25329fdbf15c6b73c3d3595
ToppCelldroplet-Bladder-BLADDER-1m-Endothelial-nan|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GIMAP5 ABCC9 PRSS23 CCDC136

1.77e-041787046bef4ef48f649c6e38ae732bc08e6d7814db588b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 ABCC9 PRSS23 NR2F1

1.77e-04178704d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 ABCC9 PRSS23 NR2F1

1.77e-0417870478a0c6340001a77f5b2d890b6263f574af2e72da
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRC GIMAP5 PIK3R1 CCDC136

1.77e-0417870428bb1e3e447261d0cb47e2b6343b17b2d74db525
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTPRC GIMAP5 PIK3R1 CCDC136

1.81e-04179704ac0c257e63a5994282d8b350c1b517cc3fbee52a
ToppCellASK428-Immune-NK_cell|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

TXNIP ABI3 PTPRC PRSS23

1.85e-04180704857d09446e3e6737e83d0f10bfda2ba282d5ba75
ToppCell10x3'2.3-week_17-19-Lymphocytic_NK-T_NK-CD56_bright_NK|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ABI3 PTPRC GIMAP5 PIK3R1

1.85e-04180704ddbab26b05f057bd78b78773381cd447bd2e2726
ToppCellMesenchymal_cells-Stromal_fibro.|Mesenchymal_cells / Lineage and Cell class

THBS1 SPATA18 LAMA2 PYGM

1.89e-04181704f8d914fdc06aaa75a4dc9158daf574ca28fa5432
ToppCelldroplet-Marrow-nan-3m-Myeloid-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 PTPRC MYCBP2 MIER1

1.93e-04182704f8c73baaaca145e2efc48f10f636feb79c8fc779
ToppCell356C-Lymphocytic-NK_cells-NK_cell_B2|356C / Donor, Lineage, Cell class and subclass (all cells)

TXNIP ABI3 PTPRC PRSS23

1.93e-0418270452baef8173df0a55307c375674a37c2488066738
ToppCellE15.5-Endothelial-large_vessel_endothelial_cell|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

TXNIP ABI3 DST PRSS23

1.93e-04182704345d0f9d5ee30434bc2aac17608ccdc9e61c8fa3
ToppCellFLU-Healthy-0|FLU / Virus stimulation, Condition and Cluster

TXNIP ABI3 PTPRC TBK1

1.97e-04183704058604ddb06b3bef131183d86b83b422dae8f6cb
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-endothelial_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 ABI3 GIMAP5 PRSS23

1.97e-04183704c9d9d7dd629ce6787502103b158a07e8684a66f8
ToppCell10x5'-lymph-node_spleen-Myeloid_Dendritic-DC1|lymph-node_spleen / Manually curated celltypes from each tissue

DST WARS1 LTBR CFI

1.97e-04183704c9e3d91f4c3395a73295b92e25608e0effb5d241
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 ABI3 GIMAP5 PRSS23

1.97e-04183704c7ef8ee2b3fcfa69cea0fdcb2041674b832933db
ToppCellfacs-Pancreas-Exocrine-18m-Endothelial-nan|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 ABI3 GIMAP5 PRSS23

1.97e-0418370492eee4bdd84965ae0bd1ed1c7f26a3b83ad0cdac
ToppCellFLU-Healthy-0|Healthy / Virus stimulation, Condition and Cluster

TXNIP ABI3 PTPRC TBK1

1.97e-041837047a6f18246c39864479e114f698581f667fa9c600
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMA2 ERC2 ABCC9 NR2F1

2.01e-04184704689a8af81a79a4bb3123cfa01958c953eab5de98
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LAMA2 ABCC9 PRSS23 NR2F1

2.01e-04184704c5436a8e45f471b8d1301abbe9c7879204537f52
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 PTPRC MYCBP2 MIER1

2.01e-041847041154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-Pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA THBS1 KRT15 PRSS23

2.05e-041857045f5df92b328be396941b5812d00454b5ff927d30
ToppCellfacs-Thymus-Flowthrough-3m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TXNIP ABI3 PTPRC MIER1

2.05e-04185704dc59b8dc459a3c444c9634a0d438cbef54c40036
ToppCelldroplet-Marrow-nan-3m-Myeloid|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THBS1 PTPRC MYCBP2 MIER1

2.05e-041857047adfa929930cfa795cbfbd9f1a0b439e08aa765d
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Mesenchymal-brain_pericyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNA THBS1 KRT15 PRSS23

2.05e-0418570498547c1b1828b76da810ed86082182afaaacdb3f
ToppCellnormal-na-Lymphocytic_T-CytoT_GZMH+-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

FLNA PTPRC PIK3R1 PRSS23

2.05e-04185704097d628f92e13250c15b550f2fd1f4225fc07558
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

THBS1 DST LAMA2 NR2F1

2.10e-041867045473283fb95cee556b1f6934cf72169b676b5bcc
ToppCellPND01-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CPNE8 ABI3 GIMAP5 PRSS23

2.14e-041877046cf7be5401b81a4eeb30840fb3733d61a24af539
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DST LAMA2 PRSS23 NR2F1

2.14e-0418770413731298bc562ec29582f5da1b4c97261284f6f1
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

FLNA SEL1L3 SCUBE3 CFI

2.14e-04187704be9fce9e74b2f170a2067f1b31d802912a578329
Drugphorbol acetate myristate

TXNIP IL12B ABI1 KRT15 DST PTPRC WARS1 HSPA4L PIK3R1 SCG2 TBK1 HSPH1 LTBR PFKFB1 PRSS23 NOS1

3.99e-0613997016CID000004792
Drug5-amidinobenzimidazole

ABI1 ABI3 CSE1L PTPRC ABI2 SCG2

7.97e-06154706CID000001800
DiseaseMalignant neoplasm of breast

PHKB FLNA THBS1 PTPRC WARS1 FAM83F UBR4 SPATA18 LAMA2 NR2F1

1.89e-0410746910C0006142
Diseaseunipolar depression, sex interaction measurement

SCG2 ERC2 MEN1

2.35e-0451693EFO_0003761, EFO_0008343
Diseaseatypical femoral fracture, response to bisphosphonate

CPNE8 LARP4B STK31

5.50e-0468693EFO_0009958, EFO_0009960
Diseaseinterferon gamma measurement, platelet-derived growth factor BB measurement, interleukin 4 measurement, interleukin 10 measurement, stromal cell-derived factor 1 alpha measurement, interleukin-6 measurement, interleukin 12 measurement, interleukin 17 measurement, vascular endothelial growth factor measurement, fibroblast growth factor basic measurement, granulocyte colony-stimulating factor measurement

SCG2 MEN1

6.33e-0416692EFO_0004750, EFO_0004753, EFO_0004762, EFO_0004810, EFO_0008130, EFO_0008142, EFO_0008165, EFO_0008174, EFO_0008184, EFO_0008264, EFO_0008293
Diseasepancreatic ductal carcinoma (is_implicated_in)

THBS1 MEN1

6.33e-0416692DOID:3587 (is_implicated_in)
Diseasemyopia (is_implicated_in)

LAMA2 LOXL3

6.33e-0416692DOID:11830 (is_implicated_in)
DiseaseGlycogen storage disease

PHKB PYGM

7.16e-0417692cv:C0017919
Diseaserenovascular hypertension (biomarker_via_orthology)

LAMA2 NOS1

8.98e-0419692DOID:1591 (biomarker_via_orthology)
Diseaseportal hypertension (implicated_via_orthology)

PIK3R1 NOS1

8.98e-0419692DOID:10762 (implicated_via_orthology)
Diseasegout

DST ABCC9 PIBF1 MEN1

1.17e-03196694EFO_0004274
DiseaseGlycogen Storage Disease

PHKB PYGM

1.82e-0327692C0017919
Diseasevital capacity

THBS1 CSE1L DST PIK3R1 LAMA2 ERC2 ATP9A PIBF1 STK31

2.28e-031236699EFO_0004312

Protein segments in the cluster

PeptideGeneStartEntry
EDFLKRIECYEVNYQ

PFKFB1

191

P16118
CQEEKIDALQLEYSY

BRAP

396

Q7Z569
YQDFADVVCYTQKAD

CFI

206

P05156
DYCENNYIQATDKRK

ABI1

31

Q8IZP0
RAVTNYVCLKDAYEE

ABCC9

256

O60706
DSYTNLERVADYCEN

ABI2

21

Q9NYB9
LERVADYCENNYIQS

ABI2

26

Q9NYB9
EKSQCALEEYVRSQY

NR2F1

346

P10589
ISAQVVDYYKEACRA

PTPN23

206

Q9H3S7
TVIQDYNYCREDEEI

MEN1

351

O00255
DYCEDNYVQATDKRK

ABI3

31

Q9P2A4
QDECKFDYVEVYETS

MFRP

351

Q9BY79
EDVSKRYECANFGEQ

LOXL3

646

P58215
CDYRQIEITIYKDDE

DST

896

Q03001
EEYYRETGITANEKC

METTL14

196

Q9HCE5
EVFNDCKYRRSYDSD

SPATA18

446

Q8TC71
NAVEEYVYEFRDKLC

HSPH1

636

Q92598
TEADAQQAYKYLREE

LARP4B

281

Q92615
TCFKEVDAEQYYSEL

TMEM63C

306

Q9P1W3
ETADVACDGYYKVQE

LCTL

81

Q6UWM7
ANYEIVEKCYKENSD

GDPD1

181

Q8N9F7
EECYYDENVARRNLS

LAMA2

351

P24043
CDYSQYFKTIEELRD

KRT15

151

P19012
QAEAEKQYEDSCRVY

ATP9A

481

O75110
EASYYRDECGKAQAE

ERC2

711

O15083
EQCQTQERYSKEYIE

PIK3R1

496

P27986
RGDNKEYEYSVECQE

IL12B

181

P29460
AYRIYCEDKQTFLQD

IMPACT

221

Q9P2X3
RDYCDNSRYNILEEV

NOS1

601

P29475
GACQEDYRQYQAKVE

GIMAP5

236

Q96F15
KELYEQECNGETVVY

PCTP

86

Q9UKL6
ECNQEAKELYRDYNH

ARV1

36

Q9H2C2
EECYVTEIDQDKYAV

FLNA

2376

P21333
VAVVDADKENCSAYY

COMTD1

181

Q86VU5
CNGDYDRTVKIDVYD

CPNE9

211

Q8IYJ1
EQYVLEKGVYRNCED

CRYBG2

1316

Q8N1P7
EEYERRNQDYKDICS

INPP5B

486

P32019
AQYSKAAQDVDECVE

SCUBE3

21

Q8IX30
CNGDYDRTIKVEVYD

CPNE8

221

Q86YQ8
YYKCNTHDEREAVIQ

PHKB

836

Q93100
ICRYKENEKVYENDD

MIER1

196

Q8N108
YELEENTEKAVECYR

RGPD1

61

P0DJD0
AYSYAVENAKDIIAC

WARS1

211

P23381
AEQIKLYYERCAEVQ

SEL1L3

441

Q68CR1
AIEADIEKYICYAEQ

NT5DC3

266

Q86UY8
DVKDETYDLLYQQCD

PRSS23

296

O95084
YTDDEDDIYKANNIA

SCG2

226

P13521
DDIYKANNIAYEDVV

SCG2

231

P13521
ETDVLAYDCAAREKY

MYCBP2

1301

O75592
QEIYDCVSQTEYREK

SWT1

846

Q5T5J6
EKVTEAQAAFYYCER

FAM83F

16

Q8NEG4
DSVDETEAVKRYNDY

SRRT

161

Q9BXP5
ENCRKTYDTTVDDNE

CCDC136

756

Q96JN2
ECRDEYKYNVEAVEL

CNOT1

1716

A5YKK6
AEYSLAQENIKTCEY

STK31

416

Q9BXU1
YKCRNEDAQYSFIRE

SPG11

1281

Q96JI7
DNCQYVYNVDQRDTD

THBS1

811

P07996
ICDNAALYAQKYDEE

CSE1L

271

P55060
ADYEDYIKCQEKVSA

PYGM

776

P11217
ERNDAKNAVEEYVYD

HSPA4L

616

O95757
YVVYEDIFDAKNACD

SF3B6

61

Q9Y3B4
YEEDRKNYSEVQIRC

PIBF1

226

Q8WXW3
TDRVDACSDQDNVYK

ZNF654

1071

Q8IZM8
YASENQTCRDQEKEY

LTBR

36

P36941
QQCKQTSEYLRYEDT

TXNIP

61

Q9H3M7
DLYTAEQAFVRCKDY

WDR35

711

Q9P2L0
AVCIETAKRYNLDDY

UBR4

4311

Q5T4S7
NCDFRVKDLQYSTDY

PTPRC

536

P08575
QCFDIEEEVSKYQEY

TBK1

636

Q9UHD2
KDYDVYSDNDICSQE

ZC3H8

71

Q8N5P1
ARADDYEQVKNVADY

ATP6V0D1

256

P61421
YQRYTEERNCEESKA

MYO3A

1241

Q8NEV4