Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionABC-type transporter activity

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

1.49e-06491466GO:0140359
GeneOntologyMolecularFunctionATPase-coupled inorganic anion transmembrane transporter activity

ABCC4 CFTR ABCC2

4.43e-05101463GO:0043225
GeneOntologyMolecularFunctionglutathione peroxidase activity

GPX3 GPX5 GPX6 LTC4S

4.90e-05281464GO:0004602
GeneOntologyMolecularFunctionalpha-L-fucosidase activity

FUCA1 FUCA2

5.31e-0521462GO:0004560
GeneOntologyMolecularFunctionfucosidase activity

FUCA1 FUCA2

5.31e-0521462GO:0015928
GeneOntologyMolecularFunctionxenobiotic transmembrane transporter activity

ABCC4 ABCB5 SLC43A3 ABCC2

1.07e-04341464GO:0042910
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

1.50e-041091466GO:0042626
GeneOntologyMolecularFunctionadiponectin binding

ADIPOR1 ADIPOR2

1.59e-0431462GO:0055100
GeneOntologyMolecularFunctionABC-type xenobiotic transporter activity

ABCC4 ABCB5 ABCC2

1.63e-04151463GO:0008559
GeneOntologyMolecularFunctionchloride channel regulator activity

CFTR CHRNA7 CHRFAM7A

1.63e-04151463GO:0017081
GeneOntologyMolecularFunctiontransporter activity

GABRD VMP1 ABCC4 ABCA4 RHBDF2 SLC38A9 SLC2A7 PIEZO1 ABCB5 CFTR MCL1 SLC43A3 ASIC5 TMC3 CHRNA7 ABCB4 TMEM120A PIEZO2 SLC25A13 ABCC2 CHRFAM7A XPR1

1.71e-04128914622GO:0005215
GeneOntologyMolecularFunctionefflux transmembrane transporter activity

ABCC4 ABCB5 XPR1

2.00e-04161463GO:0015562
GeneOntologyMolecularFunctioncarbon-sulfur lyase activity

GSTM4 ACCS LTC4S

2.00e-04161463GO:0016846
GeneOntologyMolecularFunctionmechanosensitive monoatomic ion channel activity

PIEZO1 TMC3 PIEZO2

2.88e-04181463GO:0008381
GeneOntologyMolecularFunctionglutathione binding

GSTM1 GSTM4 LTC4S

2.88e-04181463GO:0043295
GeneOntologyMolecularFunctionadipokinetic hormone receptor activity

ADIPOR1 ADIPOR2

3.16e-0441462GO:0097003
GeneOntologyMolecularFunctiontransmembrane transporter activity

GABRD ABCC4 ABCA4 SLC38A9 SLC2A7 PIEZO1 ABCB5 CFTR MCL1 SLC43A3 ASIC5 TMC3 CHRNA7 ABCB4 TMEM120A PIEZO2 SLC25A13 ABCC2 CHRFAM7A XPR1

3.80e-04118014620GO:0022857
GeneOntologyMolecularFunctionoligopeptide binding

GSTM1 GSTM4 LTC4S

3.98e-04201463GO:1900750
GeneOntologyMolecularFunctionATP hydrolysis activity

ABCC4 ERCC3 ABCA4 VWA8 ABCB5 CFTR DDX55 ABCB4 MDN1 DDX60L ABCC2

4.08e-0444114611GO:0016887
GeneOntologyMolecularFunctionleukotriene-C4 synthase activity

GSTM4 LTC4S

5.23e-0451462GO:0004464
GeneOntologyMolecularFunctionATP-dependent activity

DNHD1 ABCC4 ERCC3 ABCA4 VWA8 ABCB5 CFTR DDX55 ABCB4 MDN1 DDX60L ABCC2 TOP2B

5.85e-0461414613GO:0140657
GeneOntologyMolecularFunctionG protein-coupled receptor activity

OR4K17 CCRL2 GPR55 OR2J1 EDNRA OR6N1 ADRA2B ADRB1 OR51M1 OR4A15 MRGPRX1 AGTR1 OR52E6 OR52E1 OR52E5 LTB4R

7.60e-0488414616GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

GABRD OR4K17 CCRL2 GPR55 OR2J1 CHRNA7 EDNRA OR6N1 LIFR ADRA2B ADRB1 OR51M1 OR4A15 MRGPRX1 AGTR1 OR52E6 OR52E1 OR52E5 LTB4R KIR2DS5 CHRFAM7A

8.50e-04135314621GO:0004888
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic membrane potential

GABRD CHRNA7 ADRB1 CHRFAM7A

9.73e-04601464GO:0099529
GeneOntologyMolecularFunctionglutathione transferase activity

GSTM1 GSTM4 LTC4S

1.22e-03291463GO:0004364
GeneOntologyMolecularFunctionperoxidase activity

GPX3 GPX5 GPX6 LTC4S

1.31e-03651464GO:0004601
GeneOntologyMolecularFunctionABC-type glutathione S-conjugate transporter activity

ABCC4 ABCC2

1.44e-0381462GO:0015431
GeneOntologyMolecularFunctionalcohol transmembrane transporter activity

ABCC4 ABCA4

1.44e-0381462GO:0015665
GeneOntologyMolecularFunctionoxidoreductase activity, acting on peroxide as acceptor

GPX3 GPX5 GPX6 LTC4S

1.47e-03671464GO:0016684
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

2.00e-031781466GO:0015399
GeneOntologyMolecularFunctionpostsynaptic neurotransmitter receptor activity

GABRD CHRNA7 ADRB1 CHRFAM7A

2.23e-03751464GO:0098960
GeneOntologyMolecularFunctionadrenergic receptor activity

ADRA2B ADRB1

2.30e-03101462GO:0004935
GeneOntologyMolecularFunctionserine-type endopeptidase activity

RHBDF1 RHBDF2 C1RL F12 IMMP1L PCSK9

2.77e-031901466GO:0004252
GeneOntologyBiologicalProcesspositive regulation of CoA-transferase activity

CHRNA7 AGTR1 CHRFAM7A

2.66e-0591433GO:1905920
GeneOntologyBiologicalProcessorganic hydroxy compound transport

ABCC4 ABCA4 CFTR LDLR CHRNA7 ABCB4 ADRA2B AGTR1 ABCC2 CHRFAM7A PCSK9

4.14e-0535814311GO:0015850
GeneOntologyBiologicalProcesspositive regulation of heart rate involved in baroreceptor response to decreased systemic arterial blood pressure

CHRNA7 CHRFAM7A

4.77e-0521432GO:0001988
GeneOntologyBiologicalProcessregulation of CoA-transferase activity

CHRNA7 AGTR1 CHRFAM7A

5.17e-05111433GO:1905918
GeneOntologyBiologicalProcesspositive regulation of blood pressure

CHRNA7 ADRA2B ADRB1 AGTR1 CHRFAM7A

5.53e-05591435GO:0045777
GeneOntologyBiologicalProcessorganic anion transport

EPRS1 ABCC4 SLC38A9 ARL6IP5 CFTR SLC43A3 SELENON ABCB4 NF1 SLC25A13 ABCC2 G6PC1 OC90

6.29e-0551514313GO:0015711
GeneOntologyBiologicalProcessxenobiotic transport

ABCC4 ABCB5 SLC43A3 ABCB4 ABCC2

8.19e-05641435GO:0042908
GeneOntologyBiologicalProcesscarboxylic acid transport

EPRS1 ABCC4 SLC38A9 ARL6IP5 SLC43A3 SELENON ABCB4 NF1 SLC25A13 ABCC2 OC90

1.38e-0441014311GO:0046942
GeneOntologyBiologicalProcessbaroreceptor response to decreased systemic arterial blood pressure

CHRNA7 CHRFAM7A

1.43e-0431432GO:0001982
GeneOntologyBiologicalProcessorganic acid transport

EPRS1 ABCC4 SLC38A9 ARL6IP5 SLC43A3 SELENON ABCB4 NF1 SLC25A13 ABCC2 OC90

1.44e-0441214311GO:0015849
GeneOntologyBiologicalProcessfucose metabolic process

FUCA1 FUCA2 FUT1

1.71e-04161433GO:0006004
GeneOntologyCellularComponentnuclear outer membrane-endoplasmic reticulum membrane network

VMP1 APH1B HSD17B7 FMO3 RHBDF1 RHBDF2 PIEZO1 ARL6IP5 CFTR SGPP2 PTDSS2 SELENON PTGFRN FAF1 ATXN3L SCAP SERINC1 CNEP1R1 OR51M1 SEC62 LTC4S G6PC1 EIF2AK3 PIGO

2.27e-05132714924GO:0042175
GeneOntologyCellularComponentendoplasmic reticulum membrane

VMP1 APH1B HSD17B7 FMO3 RHBDF1 RHBDF2 PIEZO1 ARL6IP5 CFTR SGPP2 PTDSS2 SELENON PTGFRN FAF1 ATXN3L SCAP SERINC1 OR51M1 SEC62 LTC4S G6PC1 EIF2AK3 PIGO

4.43e-05129314923GO:0005789
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

VMP1 APH1B HSD17B7 FMO3 RHBDF1 RHBDF2 PIEZO1 ARL6IP5 CFTR SGPP2 PTDSS2 SELENON PTGFRN FAF1 ATXN3L SCAP SERINC1 OR51M1 SEC62 LTC4S G6PC1 EIF2AK3 PIGO

4.76e-05129914923GO:0098827
GeneOntologyCellularComponentPCSK9-LDLR complex

LDLR PCSK9

5.05e-0521492GO:1990666
GeneOntologyCellularComponentspine apparatus membrane

CHRNA7 CHRFAM7A

1.51e-0431492GO:0098897
GeneOntologyCellularComponentexternal side of apical plasma membrane

ABCC4 LCT

7.43e-0461492GO:0098591
MousePhenoairway basal cell hyperplasia

CHRNA7 CHRFAM7A

6.02e-0521092MP:0011115
MousePhenoabnormal airway basal cell differentiation

CHRNA7 CHRFAM7A

6.02e-0521092MP:0011114
MousePhenoabnormal airway basal cell morphology

CHRNA7 CHRFAM7A

6.02e-0521092MP:0011113
DomainABC_transporter_CS

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

7.58e-07421436IPR017871
DomainABC_membrane

ABCC4 ABCB5 CFTR ABCB4 ABCC2

9.27e-07241435PF00664
DomainABC_tran

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

1.71e-06481436PF00005
DomainABC_TRANSPORTER_2

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

1.71e-06481436PS50893
DomainABC_TRANSPORTER_1

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

1.93e-06491436PS00211
DomainABC_TM1F

ABCC4 ABCB5 CFTR ABCB4 ABCC2

2.09e-06281435PS50929
DomainABC1_TM_dom

ABCC4 ABCB5 CFTR ABCB4 ABCC2

2.09e-06281435IPR011527
DomainABC_transporter-like

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

2.18e-06501436IPR003439
DomainGPX_AS

GPX3 GPX5 GPX6

1.50e-0571433IPR029759
DomainAAA

ABCC4 ABCA4 VWA8 ABCB5 CFTR ABCB4 MDN1 ABCC2

1.52e-051441438SM00382
DomainAAA+_ATPase

ABCC4 ABCA4 VWA8 ABCB5 CFTR ABCB4 MDN1 ABCC2

1.52e-051441438IPR003593
DomainGLUTATHIONE_PEROXID_2

GPX3 GPX5 GPX6

2.39e-0581433PS00763
DomainGLUTATHIONE_PEROXID_1

GPX3 GPX5 GPX6

2.39e-0581433PS00460
DomainGlutathione_peroxidase

GPX3 GPX5 GPX6

2.39e-0581433IPR000889
DomainGLUTATHIONE_PEROXID_3

GPX3 GPX5 GPX6

2.39e-0581433PS51355
DomainGPX_CS

GPX3 GPX5 GPX6

2.39e-0581433IPR029760
DomainGSHPx

GPX3 GPX5 GPX6

2.39e-0581433PF00255
DomainCFTR/ABCC7

ABCC4 CFTR

5.82e-0521432IPR009147
DomainPIEZO

PIEZO1 PIEZO2

5.82e-0521432PF15917
DomainFUC_metazoa-typ

FUCA1 FUCA2

5.82e-0521432IPR016286
DomainPiezo

PIEZO1 PIEZO2

5.82e-0521432IPR027272
DomainFucosidase_C

FUCA1 FUCA2

5.82e-0521432PF16757
DomainPiezo_RRas_bdg

PIEZO1 PIEZO2

5.82e-0521432PF12166
DomainGlyco_hydro_29_CS

FUCA1 FUCA2

5.82e-0521432IPR018526
DomainRhomboid_SP

RHBDF1 RHBDF2

5.82e-0521432PF12595
DomainFucosidase_C

FUCA1 FUCA2

5.82e-0521432IPR031919
DomainRhomboid_SP

RHBDF1 RHBDF2

5.82e-0521432IPR022241
DomainPiezo_RRas-bd_dom

PIEZO1 PIEZO2

5.82e-0521432IPR031334
DomainAlpha_L_fucos

FUCA1 FUCA2

5.82e-0521432SM00812
DomainGlyco_hydro_29

FUCA1 FUCA2

5.82e-0521432IPR000933
DomainAlpha_L_fucos

FUCA1 FUCA2

5.82e-0521432PF01120
DomainALPHA_L_FUCOSIDASE

FUCA1 FUCA2

5.82e-0521432PS00385
DomainPiezo_dom

PIEZO1 PIEZO2

5.82e-0521432IPR031805
DomainDENND6

DENND6A DENND6B

5.82e-0521432IPR024224
Domain7tm_1

OR4K17 CCRL2 GPR55 OR2J1 EDNRA OR6N1 ADRA2B ADRB1 OR51M1 OR4A15 MRGPRX1 AGTR1 OR52E6 OR52E5 LTB4R

2.19e-0467714315PF00001
DomainG_PROTEIN_RECEP_F1_1

OR4K17 CCRL2 GPR55 OR2J1 EDNRA OR6N1 ADRA2B ADRB1 OR51M1 OR4A15 MRGPRX1 AGTR1 OR52E6 OR52E5 LTB4R

2.48e-0468514315PS00237
DomainG_PROTEIN_RECEP_F1_2

OR4K17 CCRL2 GPR55 OR2J1 EDNRA OR6N1 ADRA2B ADRB1 OR51M1 OR4A15 MRGPRX1 AGTR1 OR52E6 OR52E5 LTB4R

2.73e-0469114315PS50262
DomainGPCR_Rhodpsn

OR4K17 CCRL2 GPR55 OR2J1 EDNRA OR6N1 ADRA2B ADRB1 OR51M1 OR4A15 MRGPRX1 AGTR1 OR52E6 OR52E5 LTB4R

2.77e-0469214315IPR000276
DomainABL9/DENND6_dom

DENND6A DENND6B

3.46e-0441432IPR018307
DomainAvl9

DENND6A DENND6B

3.46e-0441432PF09794
DomainThioredoxin-like_fold

GPX3 GPX5 FAF1 GSTM1 GSTM4 GPX6

5.39e-041321436IPR012336
DomainWHEP_TRS_1

EPRS1 WARS1

5.73e-0451432PS00762
DomainWHEP-TRS

EPRS1 WARS1

5.73e-0451432SM00991
DomainWHEP-TRS

EPRS1 WARS1

5.73e-0451432PF00458
DomainWHEP-TRS_dom

EPRS1 WARS1

5.73e-0451432IPR000738
DomainGST_mu

GSTM1 GSTM4

5.73e-0451432IPR003081
DomainWHEP_TRS_2

EPRS1 WARS1

5.73e-0451432PS51185
Domain-

EPRS1 WARS1

8.56e-04614321.10.287.10
DomainGST_C

EPRS1 GSTM1 GSTM4

1.00e-03261433IPR004046
DomainGST_C

EPRS1 GSTM1 GSTM4

1.00e-03261433PF00043
DomainS15_NS1_RNA-bd

EPRS1 WARS1

1.58e-0381432IPR009068
DomainPeptidase_S54_rhomboid

RHBDF1 RHBDF2

1.58e-0381432IPR002610
Domain-

DNHD1 RAN ABCC4 ERCC3 ABCA4 VWA8 ABCB5 CFTR HS3ST5 DDX55 ABCB4 MDN1 DDX60L ABCC2

1.78e-03746143143.40.50.300
DomainGPCR_Rhodpsn_7TM

OR4K17 CCRL2 GPR55 EDNRA OR6N1 ADRA2B ADRB1 OR51M1 OR4A15 MRGPRX1 AGTR1 OR52E6 LTB4R

1.94e-0367014313IPR017452
DomainPeptidase_S54_rhomboid_dom

RHBDF1 RHBDF2

2.02e-0391432IPR022764
DomainRhomboid

RHBDF1 RHBDF2

2.02e-0391432PF01694
Domain-

RHBDF1 RHBDF2

2.02e-03914321.20.1540.10
Domain-

LCT FUCA1 FUCA2

2.40e-033514333.20.20.80
Domain-

GPX3 GPX5 GSTM1 GSTM4 GPX6

2.48e-0312214353.40.30.10
DomainADR_fam

ADRA2B ADRB1

2.52e-03101432IPR002233
DomainGST_C_3

GSTM1 GSTM4

2.52e-03101432PF14497
DomainGlyco_hydro_catalytic_dom

LCT FUCA1 FUCA2

3.05e-03381433IPR013781
DomainHlyIII

ADIPOR1 ADIPOR2

3.06e-03111432PF03006
DomainAdipoR/HlyIII-related

ADIPOR1 ADIPOR2

3.06e-03111432IPR004254
DomainGlutathione-S-Trfase_C-like

EPRS1 GSTM1 GSTM4

3.28e-03391433IPR010987
Domain-

EPRS1 GSTM1 GSTM4

3.28e-033914331.20.1050.10
DomainVWFA

VWA8 MDN1 COL21A1 CPNE1

3.63e-03821434PS50234
DomainVWA

VWA8 MDN1 COL21A1 CPNE1

3.96e-03841434SM00327
DomainNeurotransmitter_ion_chnl_CS

GABRD CHRNA7 CHRFAM7A

4.93e-03451433IPR018000
DomainATPase_dyneun-rel_AAA

VWA8 MDN1

4.99e-03141432IPR011704
Domain-

FUCA1 FUCA2

4.99e-031414322.60.40.1180
DomainAAA_5

VWA8 MDN1

4.99e-03141432PF07728
DomainNeur_chan_memb

GABRD CHRNA7 CHRFAM7A

5.24e-03461433PF02932
DomainNeurotrans-gated_channel_TM

GABRD CHRNA7 CHRFAM7A

5.57e-03471433IPR006029
Domain-

GABRD CHRNA7 CHRFAM7A

5.57e-034714332.70.170.10
DomainNeur_chan_LBD

GABRD CHRNA7 CHRFAM7A

5.57e-03471433PF02931
DomainNEUROTR_ION_CHANNEL

GABRD CHRNA7 CHRFAM7A

5.57e-03471433PS00236
DomainNeur_channel

GABRD CHRNA7 CHRFAM7A

5.57e-03471433IPR006201
DomainNeur_chan_lig-bd

GABRD CHRNA7 CHRFAM7A

5.57e-03471433IPR006202
DomainP-loop_NTPase

DNHD1 RAN ABCC4 ERCC3 ABCA4 VWA8 ABCB5 CFTR HS3ST5 DDX55 ABCB4 MDN1 DDX60L ABCC2

5.58e-0384814314IPR027417
DomainGlyco_hydro_b

FUCA1 FUCA2

5.73e-03151432IPR013780
DomainVWF_A

VWA8 MDN1 COL21A1 CPNE1

7.07e-03991434IPR002035
DomainPeptidase_aspartic_dom

NAPSA RTL1

7.34e-03171432IPR021109
DomainSH2

SH2D4B BLK SUPT6H GRAP2

7.58e-031011434PF00017
PathwayKEGG_ABC_TRANSPORTERS

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

1.28e-06441136M11911
PathwayWP_CHOLESTASIS

ABCC4 LDLR ABCB4 ABCC2

1.38e-05191134M45520
PathwayKEGG_GLUTATHIONE_METABOLISM

GPX3 GPX5 GSTM1 GSTM4 GPX6

4.81e-05501135M1840
PathwayKEGG_MEDICUS_REFERENCE_GLUTATHIONE_BIOSYNTHESIS

GPX3 GPX5 GPX6

7.90e-05111133M47926
PathwayWP_OXIDATIVE_STRESS_AND_REDOX_PATHWAY

GPX3 GPX5 GSTM1 GSTM4 GPX6 ABCC2

9.45e-05921136MM15823
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

1.42e-04991136MM14986
PathwayREACTOME_ABC_FAMILY_PROTEINS_MEDIATED_TRANSPORT

ABCC4 ABCA4 ABCB5 CFTR ABCB4 ABCC2

1.77e-041031136M758
Pubmed

Glutathione pathway genetic polymorphisms and lung cancer survival after platinum-based chemotherapy.

ABCC4 GPX3 GPX5 GSTM1 GSTM4 GPX6 ABCC2

4.73e-1130151720200426
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

VMP1 ABCC4 WARS1 PIEZO1 C1RL PTDSS2 SLC43A3 DDX55 SELENON PTGFRN LDLR LIFR SCAP NF1 SEC62 FUCA2 ATM EIF2AK3 PIGO GALNT4 PCSK9

6.20e-0812011512135696571
Pubmed

Hematopoietic α7 nicotinic acetylcholine receptor deficiency increases inflammation and platelet activation status, but does not aggravate atherosclerosis.

LDLR CHRNA7 CHRFAM7A

8.02e-083151325345495
Pubmed

α7 Nicotinic acetylcholine receptor is expressed in human atherosclerosis and inhibits disease in mice--brief report.

LDLR CHRNA7 CHRFAM7A

8.02e-083151325324572
Pubmed

Reduced size and macrophage content of advanced atherosclerotic lesions in mice with bone marrow specific deficiency of alpha 7 nicotinic acetylcholine receptor.

LDLR CHRNA7 CHRFAM7A

8.02e-083151325826262
Pubmed

MRP4 and CFTR in the regulation of cAMP and β-adrenergic contraction in cardiac myocytes.

ABCC4 CFTR ADRB1

3.20e-074151322381067
Pubmed

Fulfilling the promise of personalized medicine? Systematic review and field synopsis of pharmacogenetic studies.

ABCC4 LDLR GSTM1 ADRB1 AGTR1 LTC4S ABCC2

4.89e-07108151719956635
Pubmed

Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations.

HSD17B7 LDLR EDNRA ABCB4 ADIPOR1 SCAP AGTR1 G6PC1 ADIPOR2

1.61e-06250151918660489
Pubmed

Interpreting cancer genomes using systematic host network perturbations by tumour virus proteins.

VMP1 ABCC4 PIEZO1 ARL6IP5 PTDSS2 SELENON SLC35F5 TMEM120A SERINC1 SLC25A13 SEC62 PIGO

2.06e-064991511222810586
Pubmed

Characterization of the human ABC superfamily: isolation and mapping of 21 new genes using the expressed sequence tags database.

ABCC4 ABCA4 ABCB5 ABCC2

2.35e-062215148894702
Pubmed

Association analysis of 33 lipoprotein candidate genes in multi-generational families of African ancestry.

LDLR ADIPOR2 PCSK9

2.77e-067151320308432
Pubmed

HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells.

GPX3 GPX5 GPX6

2.77e-067151315910762
Pubmed

Human immunodeficiency virus type 1 Tat protein impairs selenoglutathione peroxidase expression and activity by a mechanism independent of cellular selenium uptake: consequences on cellular resistance to UV-A radiation.

GPX3 GPX5 GPX6

2.77e-067151311368344
Pubmed

A microarray minisequencing system for pharmacogenetic profiling of antihypertensive drug response.

LDLR EDNRA ADRB1 AGTR1

4.02e-0625151412544508
Pubmed

Molecular mechanism of decreased glutathione content in human immunodeficiency virus type 1 Tat-transgenic mice.

GPX3 GPX5 GPX6

4.42e-068151310652368
Pubmed

Glutathione depletion associated with the HIV-1 TAT protein mediates the extracellular appearance of acidic fibroblast growth factor.

GPX3 GPX5 GPX6

6.61e-06915139501919
Pubmed

Adiponectin receptor-1 expression is decreased in the pancreas of obese mice.

ADIPOR1 ADIPOR2

1.87e-052151219062045
Pubmed

Genetic deletion of α7 nicotinic acetylcholine receptors induces an age-dependent Alzheimer's disease-like pathology.

CHRNA7 CHRFAM7A

1.87e-052151234453977
Pubmed

Sensorimotor gating and spatial learning in α7-nicotinic receptor knockout mice.

CHRNA7 CHRFAM7A

1.87e-052151223521765
Pubmed

Effect of α7 nicotinic acetylcholine receptor activation on cardiac fibroblasts: a mechanism underlying RV fibrosis associated with cigarette smoke exposure.

CHRNA7 CHRFAM7A

1.87e-052151228258105
Pubmed

The cholinergic anti-inflammatory system limits T cell infiltration into the neurodegenerative CNS, but cannot counteract complex CNS inflammation.

CHRNA7 CHRFAM7A

1.87e-052151219344760
Pubmed

PCSK9 acts as a chaperone for the LDL receptor in the endoplasmic reticulum.

LDLR PCSK9

1.87e-052151224144304
Pubmed

SERPING1 and F12 combined variants in a hereditary angioedema family.

F12 SERPING1

1.87e-052151229885370
Pubmed

Bidirectional Regulation of Aggression in Mice by Hippocampal Alpha-7 Nicotinic Acetylcholine Receptors.

CHRNA7 CHRFAM7A

1.87e-052151229114104
Pubmed

Antagonism of secreted PCSK9 increases low density lipoprotein receptor expression in HepG2 cells.

LDLR PCSK9

1.87e-052151219224862
Pubmed

Omental fat expression of adiponectin and adiponectin receptors in non-obese women with PCOS: a preliminary study.

ADIPOR1 ADIPOR2

1.87e-052151219909601
Pubmed

Characterization, regulation of the expression and putative roles of two glutathione peroxidase proteins found in the mouse epididymis.

GPX3 GPX5

1.87e-052151210645275
Pubmed

Reduced CHRNA7 expression in C3H mice is associated with increases in hippocampal parvalbumin and glutamate decarboxylase-67 (GAD67) as well as altered levels of GABA(A) receptor subunits.

CHRNA7 CHRFAM7A

1.87e-052151224836856
Pubmed

Serum proprotein convertase subtilisin/kexin type 9 and cell surface low-density lipoprotein receptor: evidence for a reciprocal regulation.

LDLR PCSK9

1.87e-052151223690465
Pubmed

Studies of sperm from mutant mice suggesting that two neurotransmitter receptors are important to the zona pellucida-initiated acrosome reaction.

CHRNA7 CHRFAM7A

1.87e-052151215948184
Pubmed

Alpha7 nicotinic acetylcholine receptor mediates chronic nicotine inhalation-induced cardiopulmonary dysfunction.

CHRNA7 CHRFAM7A

1.87e-052151235678315
Pubmed

Hypercholesterolemia Induced by a PCSK9 Gain-of-Function Mutation Augments Angiotensin II-Induced Abdominal Aortic Aneurysms in C57BL/6 Mice-Brief Report.

LDLR PCSK9

1.87e-052151227470509
Pubmed

Functional role of alpha7 nicotinic receptor in physiological control of cutaneous homeostasis.

CHRNA7 CHRFAM7A

1.87e-052151212628457
Pubmed

Binding to the low-density lipoprotein receptor accelerates futile catalytic cycling in PCSK9 and raises the equilibrium level of intramolecular acylenzyme.

LDLR PCSK9

1.87e-052151219222187
Pubmed

Prenatal nicotine exposure alters lung function and airway geometry through α7 nicotinic receptors.

CHRNA7 CHRFAM7A

1.87e-052151222246862
Pubmed

Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion.

GSTM1 GSTM4

1.87e-05215123174634
Pubmed

Attenuation of Excess TNF-α Release in Crohn's Disease by Silencing of iRHOMs 1/2 and the Restoration of TGF-β Mediated Immunosuppression Through Modulation of TACE Trafficking.

RHBDF1 RHBDF2

1.87e-052151235585977
Pubmed

New PCSK9 inhibitor miR-552-3p reduces LDL-C via enhancing LDLR in high fat diet-fed mice.

LDLR PCSK9

1.87e-052151233737240
Pubmed

Involvement of AdipoR receptor in adiponectin-induced motility and alpha2beta1 integrin upregulation in human chondrosarcoma cells.

ADIPOR1 ADIPOR2

1.87e-052151219549705
Pubmed

Having excess levels of PCSK9 is not sufficient to induce complex formation between PCSK9 and the LDL receptor.

LDLR PCSK9

1.87e-052151224486405
Pubmed

Expression of human apolipoprotein A-II and its effect on high density lipoproteins in transgenic mice.

CHRNA7 CHRFAM7A

1.87e-05215121400473
Pubmed

Structural requirements for PCSK9-mediated degradation of the low-density lipoprotein receptor.

LDLR PCSK9

1.87e-052151218753623
Pubmed

Differential expression of PIEZO1 and PIEZO2 mechanosensitive channels in ocular tissues implicates diverse functional roles.

PIEZO1 PIEZO2

1.87e-052151237820892
Pubmed

INT6/EIF3E interacts with ATM and is required for proper execution of the DNA damage response in human cells.

EIF3E ATM

1.87e-052151222508697
Pubmed

Activation of Alpha 7 Cholinergic Nicotinic Receptors Reduce Blood-Brain Barrier Permeability following Experimental Traumatic Brain Injury.

CHRNA7 CHRFAM7A

1.87e-052151226937017
Pubmed

PCSK9 and LDLR degradation: regulatory mechanisms in circulation and in cells.

LDLR PCSK9

1.87e-052151225110901
Pubmed

Characterization of LDLR rs5925 and PCSK9 rs505151 genetic variants frequencies in healthy subjects from northern Chile: Influence on plasma lipid levels.

LDLR PCSK9

1.87e-052151231441123
Pubmed

Impaired attention is central to the cognitive deficits observed in alpha 7 deficient mice.

CHRNA7 CHRFAM7A

1.87e-052151216650968
Pubmed

Long-term improvements in sensory inhibition with gestational choline supplementation linked to α7 nicotinic receptors through studies in Chrna7 null mutation mice.

CHRNA7 CHRFAM7A

1.87e-052151224462939
Pubmed

Probing the putative α7 nAChR/NMDAR complex in human and murine cortex and hippocampus: Different degrees of complex formation in healthy and Alzheimer brain tissue.

CHRNA7 CHRFAM7A

1.87e-052151229261717
Pubmed

Altered hippocampal circuit function in C3H alpha7 null mutant heterozygous mice.

CHRNA7 CHRFAM7A

1.87e-052151218199426
Pubmed

Neuronal nicotinic alpha7 receptors modulate inflammatory cytokine production in the skin following ultraviolet radiation.

CHRNA7 CHRFAM7A

1.87e-052151218077004
Pubmed

Smoking in adult attention-deficit/hyperactivity disorder: interaction between 15q13 nicotinic genes and Temperament Character Inventory scores.

CHRNA7 CHRFAM7A

1.87e-052151219462340
Pubmed

Dual action of adiponectin on insulin secretion in insulin-resistant mice.

ADIPOR1 ADIPOR2

1.87e-052151215358228
Pubmed

NMR structural analysis of alpha-bungarotoxin and its complex with the principal alpha-neurotoxin-binding sequence on the alpha 7 subunit of a neuronal nicotinic acetylcholine receptor.

CHRNA7 CHRFAM7A

1.87e-052151211790782
Pubmed

Regulation of adiponectin receptor gene expression in diabetic mice.

ADIPOR1 ADIPOR2

1.87e-052151215613685
Pubmed

Effect of a splice site mutation in LDLR gene and two variations in PCSK9 gene in Tunisian families with familial hypercholesterolaemia.

LDLR PCSK9

1.87e-052151221115573
Pubmed

Genetic deletion of α7 nAChRs reduces hippocampal granule and pyramidal cell number in both sexes but impairs pattern separation in males only.

CHRNA7 CHRFAM7A

1.87e-052151237746145
Pubmed

A 2-base pair deletion polymorphism in the partial duplication of the alpha7 nicotinic acetylcholine gene (CHRFAM7A) on chromosome 15q14 is associated with schizophrenia.

CHRNA7 CHRFAM7A

1.87e-052151219631623
Pubmed

Deletion of the alpha7 nicotinic receptor subunit gene results in increased sensitivity to several behavioral effects produced by alcohol.

CHRNA7 CHRFAM7A

1.87e-052151215770102
Pubmed

LDLR and PCSK9 Are Associated with the Presence of Antiphospholipid Antibodies and the Development of Thrombosis in aPLA Carriers.

LDLR PCSK9

1.87e-052151226820623
Pubmed

Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation.

RHBDF1 RHBDF2

1.87e-052151232646486
Pubmed

Binding of proprotein convertase subtilisin/kexin type 9 to epidermal growth factor-like repeat A of low density lipoprotein receptor decreases receptor recycling and increases degradation.

LDLR PCSK9

1.87e-052151217452316
Pubmed

Alpha 7 subunit of nAChR regulates migration of human mesenchymal stem cells.

CHRNA7 CHRFAM7A

1.87e-052151220720594
Pubmed

The regulation of adiponectin receptors in human prostate cancer cell lines.

ADIPOR1 ADIPOR2

1.87e-052151216899222
Pubmed

Blood lipid-related low-frequency variants in LDLR and PCSK9 are associated with onset age and risk of myocardial infarction in Japanese.

LDLR PCSK9

1.87e-052151229802317
Pubmed

Chrna7 genotype is linked with alpha7 nicotinic receptor expression but not alpha7 RNA levels.

CHRNA7 CHRFAM7A

1.87e-052151219368846
Pubmed

The role of dorsal root ganglia alpha-7 nicotinic acetylcholine receptor in complete Freund's adjuvant-induced chronic inflammatory pain.

CHRNA7 CHRFAM7A

1.87e-052151234514543
Pubmed

α7 nicotinic acetylcholine receptor (α7nAChR) expression in bone marrow-derived non-T cells is required for the inflammatory reflex.

CHRNA7 CHRFAM7A

1.87e-052151222183893
Pubmed

Evidence suggesting that the mouse sperm acrosome reaction initiated by the zona pellucida involves an alpha7 nicotinic acetylcholine receptor.

CHRNA7 CHRFAM7A

1.87e-052151212606407
Pubmed

Polymorphisms in adiponectin receptor genes ADIPOR1 and ADIPOR2 and insulin resistance.

ADIPOR1 ADIPOR2

1.87e-052151217716299
Pubmed

Low-abundant adiponectin receptors in visceral adipose tissue of humans and rats are further reduced in diabetic animals.

ADIPOR1 ADIPOR2

1.87e-052151220470935
Pubmed

Nicotine elicits prolonged calcium signaling along ventral hippocampal axons.

CHRNA7 CHRFAM7A

1.87e-052151224349346
Pubmed

Cholinergic modulation of appetite-related synapses in mouse lateral hypothalamic slice.

CHRNA7 CHRFAM7A

1.87e-052151216319313
Pubmed

Impaired synaptic plasticity in the visual cortex of mice lacking α7-nicotinic receptor subunit.

CHRNA7 CHRFAM7A

1.87e-052151225797465
Pubmed

Adiponectin receptor expression is elevated in colorectal carcinomas but not in gastrointestinal stromal tumors.

ADIPOR1 ADIPOR2

1.87e-052151218310295
Pubmed

Pharmacologic activation of cholinergic alpha7 nicotinic receptors mitigates depressive-like behavior in a mouse model of chronic stress.

CHRNA7 CHRFAM7A

1.87e-052151229197398
Pubmed

Cholinergic signaling via the α7 nicotinic acetylcholine receptor regulates the migration of monocyte-derived macrophages during acute inflammation.

CHRNA7 CHRFAM7A

1.87e-052151238178134
Pubmed

In hippocampal oriens interneurons anti-Hebbian long-term potentiation requires cholinergic signaling via α7 nicotinic acetylcholine receptors.

CHRNA7 CHRFAM7A

1.87e-052151223325242
Pubmed

Identification of amino acid residues in the ligand binding repeats of LDL receptor important for PCSK9 binding.

LDLR PCSK9

1.87e-052151230617148
Pubmed

Alpha7-nicotinic receptors modulate nicotine-induced reinforcement and extracellular dopamine outflow in the mesolimbic system in mice.

CHRNA7 CHRFAM7A

1.87e-052151221901321
Pubmed

Polymorphisms of ADIPOR1 and ADIPOR2 are associated with phenotypes of type 2 diabetes in Koreans.

ADIPOR1 ADIPOR2

1.87e-052151218466348
Pubmed

Adiponectin receptors are expressed in hypothalamus and colocalized with proopiomelanocortin and neuropeptide Y in rodent arcuate neurons.

ADIPOR1 ADIPOR2

1.87e-052151218971219
Pubmed

Neuronal nicotinic alpha7 receptors modulate early neutrophil infiltration to sites of skin inflammation.

CHRNA7 CHRFAM7A

1.87e-052151220624304
Pubmed

Non-hematopoietic deficiency of proprotein convertase subtilisin/kexin type 9 deficiency leads to more severe anemia in a murine model of sickle cell disease.

LDLR PCSK9

1.87e-052151233020528
Pubmed

Identification of a novel major histocompatibility complex class II-restricted tumor antigen resulting from a chromosomal rearrangement recognized by CD4(+) T cells.

LDLR FUT1

1.87e-052151210330445
Pubmed

Mice homozygous for the L250T mutation in the alpha7 nicotinic acetylcholine receptor show increased neuronal apoptosis and die within 1 day of birth.

CHRNA7 CHRFAM7A

1.87e-052151210800961
Pubmed

The role of PIEZO ion channels in the musculoskeletal system.

PIEZO1 PIEZO2

1.87e-052151236717101
Pubmed

Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.

LDLR PCSK9

1.87e-052151233886544
Pubmed

Characterization of allelic variants at chromosome 15q14 in schizophrenia.

CHRNA7 CHRFAM7A

1.87e-052151216417613
Pubmed

Structural insights into adiponectin receptors suggest ceramidase activity.

ADIPOR1 ADIPOR2

1.87e-052151228329765
Pubmed

Localization of novel adiponectin receptor constructs.

ADIPOR1 ADIPOR2

1.87e-052151217118803
Pubmed

Regional variation in aortic AT1b receptor mRNA abundance is associated with contractility but unrelated to atherosclerosis and aortic aneurysms.

LDLR AGTR1

1.87e-052151223119030
Pubmed

Absence of alpha7-containing neuronal nicotinic acetylcholine receptors does not prevent nicotine-induced seizures.

CHRNA7 CHRFAM7A

1.87e-052151211834293
Pubmed

in vitro Anti-Proliferative Effect of Adiponectin on Human Endometriotic Stromal Cells through AdipoR1 and AdipoR2 Gene Receptor Expression.

ADIPOR1 ADIPOR2

1.87e-052151226459399
Pubmed

Antagonism of Cerebral High Mobility Group Box 1 Ameliorates Dendritic Cell Dysfunction in Sepsis.

CHRNA7 CHRFAM7A

1.87e-052151234512319
Pubmed

Visual acuity is reduced in alpha 7 nicotinic receptor knockout mice.

CHRNA7 CHRFAM7A

1.87e-052151222281823
Pubmed

Central role of alpha7 nicotinic receptor in differentiation of the stratified squamous epithelium.

CHRNA7 CHRFAM7A

1.87e-052151212391028
Pubmed

Mouse muscle denervation increases expression of an alpha7 nicotinic receptor with unusual pharmacology.

CHRNA7 CHRFAM7A

1.87e-052151212562921
Pubmed

AdipoR1 and 2 are expressed on warm sensitive neurons of the hypothalamic preoptic area and contribute to central hyperthermic effects of adiponectin.

ADIPOR1 ADIPOR2

1.87e-052151222000082
InteractionSLC22A4 interactions

VMP1 KNTC1 HSD17B7 PTDSS2 TMEM120A SERINC1 IMMP1L ATM SERPINF2 PIGO

1.32e-0619214510int:SLC22A4
GeneFamilyAdiponectin receptors|Progestin and adipoQ receptor family

ADIPOR1 ADIPOR2

2.67e-052942293
GeneFamilyATP binding cassette subfamily C

ABCC4 CFTR ABCC2

3.75e-0513943807
GeneFamilySelenoproteins

GPX3 SELENON GPX6

2.88e-0425943890
GeneFamilyGuanylate cyclase receptors|DENN/MADD domain containing

DENND4A DENND6A DENND6B

2.88e-0425943504
GeneFamilyAdrenoceptors

ADRA2B ADRB1

9.40e-049942169
GeneFamilyProgestin and adipoQ receptor family

ADIPOR1 ADIPOR2

1.43e-0311942930
GeneFamilyATP binding cassette subfamily B

ABCB5 ABCB4

1.43e-0311942806
GeneFamilySH2 domain containing

SH2D4B BLK SUPT6H GRAP2

1.90e-03101944741
GeneFamilyOlfactory receptors, family 52

OR52E6 OR52E1 OR52E5

2.11e-0349943165
GeneFamilyRhomboid family

RHBDF1 RHBDF2

2.34e-0314942926
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

C1RL CSMD2 SUSD5

3.25e-03579431179
GeneFamilyAminoacyl tRNA synthetases, Class I

EPRS1 WARS1

4.32e-0319942131
GeneFamilyGlutathione S-transferases

GSTM1 GSTM4

7.42e-0325942567
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_k-means-cluster#5_top-relative-expression-ranked_1000

NAPSA VMP1 APH1B CFTR PDLIM5 SGK2 AGTR1 SERPINF2 FGGY PIGO PCSK9

1.42e-0626713811gudmap_developingKidney_e14.5 whole kidney - wildtype_1000_k5
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_top-relative-expression-ranked_1000

NAPSA VMP1 APH1B EPRS1 HSD17B7 MIS18BP1 WARS1 CFTR SGPP2 PDLIM5 SGK2 GPX6 AGTR1 ATM SERPINF2 FGGY PIGO PCSK9

2.24e-0676113818gudmap_developingKidney_e14.5 whole kidney - wildtype_emap-6674_1000
CoexpressionAtlasDevelopingKidney_e14.5 whole kidney - wildtype_emap-6674_top-relative-expression-ranked_500

NAPSA EPRS1 MIS18BP1 CFTR PDLIM5 SGK2 AGTR1 ATM SERPINF2 FGGY PIGO PCSK9

8.32e-0638513812gudmap_developingKidney_e14.5 whole kidney - wildtype_emap-6674_500
CoexpressionAtlaskidney_adult_JuxtaGlom_Ren1_k-means-cluster#2_top-relative-expression-ranked_1000

NAPSA VWA8 SGPP2 GPX3 SGK2 GPX6 FUCA1 FUCA2 ABCC2 SERPINF2 G6PC1

1.17e-0533313811gudmap_kidney_adult_JuxtaGlom_Ren1_k2_1000
CoexpressionAtlaskidney_P0_JuxtaGlom_Ren1_k-means-cluster#4_top-relative-expression-ranked_1000

NAPSA SGPP2 GPX3 ADRA2B GPX6 HERC3 FUCA2 ABCC2 FGGY

4.64e-052561389gudmap_kidney_P0_JuxtaGlom_Ren1_k4_1000
CoexpressionAtlaskidney_e10.5_UretericTip_HoxB7_k-means-cluster#1_top-relative-expression-ranked_1000

GPX3 GPX6 SLC25A13 ZC3H12C FUCA2 FGGY

9.19e-051121386gudmap_kidney_e10.5_UretericTip_HoxB7_k1_1000
CoexpressionAtlasDevelopingKidney_e15.5_Proximal Tubules_emap-28005_top-relative-expression-ranked_1000

NAPSA APH1B SLC38A9 CFTR SGPP2 DNAAF9 SGK2 EML5 AGTR1 FUCA2 ABCC2 SERPINF2 G6PC1 FGGY PCSK9

1.26e-0475813815gudmap_developingKidney_e15.5_Proximal Tubules_1000
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1RL F12 ABCB4 GSTM1 GSTM4 SERPING1 ABCC2 SERPINF2 G6PC1

6.01e-091681509b98af4043dfa5dfa4413e482879fad88de484675
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1RL F12 ABCB4 GSTM1 GSTM4 SERPING1 ABCC2 SERPINF2 G6PC1

6.01e-091681509073b53d4cee6bc8c5c6fce51cf6cd9c316478f69
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO3 C1RL F12 ABCB4 GSTM4 SERPING1 ABCC2 SERPINF2 G6PC1

8.59e-0917515095c38d4b6c03473d841e6203a7efaa6dcb2d59386
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F12 ABCB4 SGK2 GSTM1 GSTM4 SLC25A13 ABCC2 G6PC1

7.35e-081601508c42bcc6c7d113f0db43febb088b75ca4ac7cb7a3
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-Hepatocyte_(Pericentral_and_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HSD17B7 F12 GSTM4 SERPING1 SERPINF2 G6PC1 ADIPOR2 PCSK9

9.33e-081651508d449a568664a81d9b5538e8f409301448a32ac37
ToppCelldroplet-Liver-HEPATOCYTES|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F12 ABCB4 GSTM1 GSTM4 SERPING1 ABCC2 SERPINF2 G6PC1

1.12e-071691508f195467438c589f87224bde7da720dea072d110c
ToppCelldroplet-Liver-HEPATOCYTES-1m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F12 ABCB4 GSTM1 GSTM4 SERPING1 ABCC2 SERPINF2 G6PC1

1.12e-0716915087785cab967a33560830c394c918d6ce625103858
ToppCell356C-Fibroblasts-Fibroblast-G|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO3 GPX3 EDNRA PIEZO2 COL21A1 ST6GALNAC5 AGTR1 SERPING1

1.60e-0717715088220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell356C-Fibroblasts-Fibroblast-G-|356C / Donor, Lineage, Cell class and subclass (all cells)

FMO3 GPX3 EDNRA PIEZO2 COL21A1 ST6GALNAC5 AGTR1 SERPING1

1.60e-0717715087617270f49cd6b7ba66db72d20560cee985012b2
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCK5 C1RL LDLR F12 ABCB4 ABCC2 SERPINF2 PCSK9

1.98e-071821508770ce9f3f4538d0181a0181543841bc964c68274
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCK5 C1RL LDLR F12 ABCB4 ABCC2 SERPINF2 PCSK9

1.98e-07182150877ab860e2add49dad0c1ffbfc64278ad499dfbd5
ToppCellfacs-Liver-Hepatocytes-24m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCK5 C1RL LDLR F12 ABCB4 ABCC2 SERPINF2 PCSK9

1.98e-0718215084921c7d5687cc79f896b39753bb621d7e3d2972f
ToppCellfacs-Liver-Hepatocytes-24m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCK5 C1RL LDLR F12 ABCB4 ABCC2 PCSK9

2.96e-061831507d0721c6aa426953a520d40e976b6e65aa7ca65e8
ToppCellCOPD-Endothelial-VE_Arterial|Endothelial / Disease state, Lineage and Cell class

ABCC4 GPX3 LDLR LIFR COL21A1 RASGEF1B ADIPOR2

3.92e-061911507ef16ad1c1cd2c0c0377957398c98775b62a81754
ToppCellPND01-03-samps-Mesenchymal-Matrix_fibroblast-FB-2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

GPX3 GPR55 EDNRA SCAP GPX6 SERPING1

4.20e-0612515066cd741dd1c7ee6b16437cca7c15c99b5c95603fc
ToppCell5'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PGM2L1 TMC3 F12 PDLIM5 EML5 CHRFAM7A XPR1

5.14e-061991507b4824d3683a4e3025b8e74a0f1755b331b2a0ba7
ToppCellbackground|World / Sample and Cell Type and Tumor Cluster (all cells)

FMO3 GPX3 MCL1 F12 RASGEF1B SERPING1 G6PC1

5.14e-0619915075a6d0e00bfe1351eea192b54020bedeef78854e9
ToppCellbackground-Hepatocytes|World / Sample and Cell Type and Tumor Cluster (all cells)

FMO3 GPX3 MCL1 F12 RASGEF1B SERPING1 G6PC1

5.31e-062001507423cca10df6ae0489a8fe7e7df87e70364dac022
ToppCell367C-Myeloid-Macrophage-SPP1+_Macrophage_2|367C / Donor, Lineage, Cell class and subclass (all cells)

CCRL2 SLC43A3 ABCB4 ADRA2B RASGEF1B EIF2AK3

8.40e-061411506e409da87da5a38ba4d0ccc5e3f8bd89f480f9dab
ToppCellPND01-03-samps-Mesenchymal-Myofibroblast-myofibroblast_-_immature_2|PND01-03-samps / Age Group, Lineage, Cell class and subclass

APH1B GSTM4 ST6GALNAC5 KIAA1755 ACCS PIGO

9.11e-061431506abe6ec0f6956b87f394d537926eb2427fcfad93f
ToppCellPND03-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SLC43A3 DNAAF9 THSD1 PIEZO2 ADRB1 CPNE1

1.55e-0515715062c946c6ab284fac3c25db688ed0aabe5a3f9ffa5
ToppCellfacs-Kidney|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA GPX3 SGK2 ADRA2B SERPINF2 G6PC1

2.27e-051681506d2f17a470e04f8f0edb111894027bcfc6ee1a12f
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

GPX3 SLC43A3 AGTR1 UGP2 SERPING1 FUCA1

2.35e-05169150684b898a9fd8ced67c6a501d5cef6416f519902c4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1-3_VIP_SSTR1|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB5 CHRNA7 EDNRA ABCB4 COL21A1 CHRFAM7A

2.59e-051721506458fe1ae92620882dbc95c989a6da9b2ca216b5b
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A GPX3 MCL1 LIFR DENND6A ADRB1

2.86e-0517515061ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellControl|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HS3ST5 THSD1 USP9Y LIFR ST6GALNAC5 LTC4S

3.05e-051771506b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR55 SELENON F12 GRAP2 G6PC1 CD96

3.15e-051781506d9eba884e18a0c89bdc70c194bfe4d62cca164fa
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic-hematopoietic_stem_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR55 SELENON F12 GRAP2 G6PC1 CD96

3.15e-051781506b03aa1de9d20895ebad55f6fcd6fe7a49335db5a
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Hematologic|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR55 SELENON F12 GRAP2 G6PC1 CD96

3.15e-0517815060f5cf34609df791c8baebfdc6590f6eb4dbe0509
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CFTR SGPP2 PGM2L1 CSMD2 ST6GALNAC5 AGTR1

3.15e-051781506a0ab20c588e7d43d0320d4779d9ab95c1c86e297
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

NAPSA ABCC4 CFTR SGPP2 LDLR EML5

3.79e-051841506ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FMO3 GPX3 C1RL CSMD2 SERPING1 CHRFAM7A

3.90e-0518515069faa35ceb89ccd2979072286f063687c9f846ce3
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Clear_Cell_Renal_Carcinoma-2|TCGA-Kidney / Sample_Type by Project: Shred V9

GABRD FMO3 SLC43A3 THSD1 EDNRA COL21A1

4.02e-0518615061e6526fc9e9381b7ace864588cc7bd80194338d6
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

NAPSA CCRL2 GPR55 GSTM4 SND1-IT1 FGGY

4.14e-051871506689b3cc76f1e04bd35a7d3ce19e9f08744a7835b
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

NAPSA CCRL2 GPR55 GSTM4 SND1-IT1 FGGY

4.14e-0518715064527d6426f2c4397e47f12439a13a8c14fd2aab2
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

NAPSA ABCC4 HSD17B7 WARS1 CFTR SGPP2

4.27e-051881506ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell3'-Adult-Distal_Rectal-Epithelial-goblet-Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MARVELD1 SELENON ADRA2B DENND6A EIF2AK3 KRT10-AS1

4.40e-0518915067dad62bd50c197838058e89abd0ee387de3e83cd
ToppCellFetal_29-31_weeks-Immune-B_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DENND4A MIS18BP1 RHBDF2 ABCB4 BLK EIF2AK3

4.53e-051901506424550418c1bd4eb070cf3c41cf09fa9d89aef37
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PDLIM5 EDNRA PIEZO2 COL21A1 SUSD5 KIAA1755

4.53e-05190150670c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HSD17B7 PGM2L1 DDX55 CPNE1 HERC3 SND1-IT1

4.53e-0519015063f0c7d130f66faea778fe567604edf1b4cdf85b3
ToppCell10x3'2.3-week_14-16-Hematopoietic-HSC/MPP_and_pro-ELP|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ARL6IP5 EIF3E BLK DENND6B CD96 TOP2B

4.80e-05192150638ec82aa2ec4f2c0a843e83f7fe54f6b2483ca3d
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HSD17B7 PGM2L1 DDX55 CPNE1 HERC3 SND1-IT1

4.80e-051921506c09dcc73ff9c3855a0f3d7bfa0d5c99c09a117f2
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A MCL1 LIFR ADRB1 SERPING1 LTC4S

4.94e-05193150606b65110db974f4ef90d3511ff34428976a52c9c
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A MCL1 LIFR ADRB1 SERPING1 LTC4S

4.94e-0519315069c16032bc03df8760ae199e8f19fdafa4c3f1827
ToppCell5'-Adult-SmallIntestine-Mesenchymal-fibroblastic-mLN_Stroma_(FMO2+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

GPX3 SLC43A3 THSD1 EDNRA IMMP1L SERPING1

4.94e-0519315067c0d84b92470bfda2db1e5007feee7c1235a0a78
ToppCellfacs-Brain_Myeloid-Hippocampus-3m|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A MCL1 LIFR ADRB1 SERPING1 LTC4S

4.94e-051931506a4f91bca5eaa985982d33a528f7566ffde154d47
ToppCell10x5'-GI_small-bowel|World / Manually curated celltypes from each tissue

TSPYL2 GPR55 LDLR LGALS4 GRAP2 CD96

4.94e-051931506cd89dfe53a114078f06343049685883c8e26508f
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-nan|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DENND4A MCL1 LIFR ADRB1 SERPING1 LTC4S

4.94e-051931506b39d7feaac4ff8f7409cd3d15e8f3c6391367275
ToppCellControl-Myeloid-TRAM2|Control / Condition, Lineage and Cell class

WARS1 ABCB5 CCRL2 SLC43A3 RASGEF1B SERPING1

5.08e-051941506d951dd1274d3ff1ac30671ec4153a4a8bc97b53f
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|Classical_Monocyte / Disease condition and Cell class

VMP1 WARS1 LDLR LIMK2 RASGEF1B SERPING1

5.23e-0519515061992a1673b7213e25f3c76ac77da35c57daceddd
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|COVID-19_Severe / Disease condition and Cell class

VMP1 WARS1 CCRL2 LDLR RASGEF1B SERPING1

5.23e-051951506787ea9f38ad8e2a836222ca97f4d927f7e79517d
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

FMO3 GPX3 EDNRA PIEZO2 COL21A1 SERPING1

5.53e-051971506156155c2f0c1a2461e45803da578af18ee221660
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NAPSA ABCC4 CFTR TSPYL2 LDLR EML5

5.53e-0519715061485933986921ff45669d9b7501c8d17050b3e97
ToppCellnormal_Lung-Fibroblasts-COL13A1+_matrix_FBs|normal_Lung / Location, Cell class and cell subclass

FMO3 GPX3 EDNRA PIEZO2 COL21A1 AGTR1

5.53e-0519715066c57ab2efb8363828e24211c4d45e58bb73a9a4d
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Dendritic_cell / Region, Cell class and subclass

DNHD1 USP9Y MTMR10 LGALS4 BLK PIEZO2

5.53e-0519715068545baf923ddf84c5ce9414a36d810603be52401
ToppCellPCW_10-12|World / Celltypes from embryonic and fetal-stage human lung

DENND4A GPX3 USP9Y LIFR COL21A1 AGTR1

5.53e-05197150647fd8b0d596c5db1a722473c8efbb17a6bbe7538
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

FMO3 GPX3 EDNRA PIEZO2 COL21A1 SERPING1

5.53e-051971506d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

NAPSA ABCC4 CFTR TSPYL2 SLC43A3 LDLR

5.53e-0519715061a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCelltumor_Lung-Fibroblasts-COL13A1+_matrix_FBs|Fibroblasts / Location, Cell class and cell subclass

FMO3 ARL6IP5 EIF3E GPX3 PIEZO2 SERPING1

5.53e-05197150644f37a98f07c3e46a7e8fd3b64c2b2b44d5bbe40
ToppCell3'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NAPSA CFTR SGPP2 LDLR LGALS4 FGGY

5.53e-051971506bf10727fbe90b71d2ac60a11711e5f0701b3799d
ToppCell(5)_Fibroblasts-(5)_Fibroblast-G|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)

FMO3 GPX3 EDNRA COL21A1 RASGEF1B SERPING1

5.53e-051971506a21a710c824f9e5c7ef1674168d1ce5aef85bd35
ToppCellCOVID-19_Mild|World / Disease condition and Cell class

WARS1 MCL1 LDLR RASGEF1B SERPING1 DDX60L

5.69e-05198150661ceb2245b6cb58e308b999a61d218c89dbc615e
ToppCellwk_08-11-Mesenchymal-Fibroblast-intermediate_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EIF3E LIFR PIEZO2 COL21A1 AGTR1 SERPING1

5.85e-051991506f9e3fb974ba8fe1b6d99892577549ef143df9e08
ToppCell(5)_Fibroblast-G|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

FMO3 GPX3 EDNRA PIEZO2 COL21A1 SERPING1

5.85e-051991506b4a737575be9f8c65771832dd8cd25328d5dae0d
ToppCelldistal-Endothelial-Capillary-1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

SYN3 GPX3 THSD1 LIFR ADRB1 LTC4S

5.85e-051991506d27fbd9a651821b2859dfa80bce4e6fc6f8299fc
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FMO3 GPX3 EDNRA ADRA2B AGTR1 SERPING1

5.85e-051991506bd9b36dcf61eaa628ce1b70d21c5783b64c29e8f
ToppCell343B-Fibroblasts-Fibroblast-G|343B / Donor, Lineage, Cell class and subclass (all cells)

FMO3 GPX3 EDNRA PIEZO2 COL21A1 SERPING1

5.85e-051991506f4b6c095cbe7a38b310adc49be4069e4d56e6a66
ToppCell343B-Fibroblasts-Fibroblast-G-|343B / Donor, Lineage, Cell class and subclass (all cells)

FMO3 GPX3 EDNRA PIEZO2 COL21A1 SERPING1

5.85e-0519915069c6d1c328bfbb6547f4c7bb2a784576a56bd72af
ToppCell3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FMO3 GPX3 EDNRA ADRA2B AGTR1 SERPING1

5.85e-051991506e751eb67510f8a5842dcfed44134160919cdb713
ToppCell343B-Fibroblasts-Fibroblast-G|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FMO3 GPX3 EDNRA COL21A1 RASGEF1B SERPING1

5.85e-051991506212e89d097753790061310373a1fafba773488b6
ToppCell343B-Fibroblasts-Fibroblast-G-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FMO3 GPX3 EDNRA COL21A1 RASGEF1B SERPING1

5.85e-05199150614b676aa289c0578a37be32cec3ea285c79d97cc
ToppCellwk_20-22-Mesenchymal-Fibroblast-Alveolar_fibro|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

GABRD LIFR PIEZO2 COL21A1 AGTR1 SERPING1

6.02e-0520015060ed49c2177b58269ff7653db6be7d68633a5d34a
ToppCellwk_08-11-Mesenchymal-Fibroblast|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

EIF3E EDNRA LIFR PIEZO2 COL21A1 SERPING1

6.02e-052001506482dfbbd8958b64c31568dccbffe3cc9589f876b
ToppCellCOVID-19_Convalescent-PLT_3|World / Disease Group and Platelet Clusters

VWA8 DNAAF9 SCAP ATM CD96

1.01e-041371505bb54bb81b450462ad521b57e1a07a80ce1678e67
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c02-AQP3|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ITFG2 TSPYL2 CLYBL GRAP2 TOP2B

1.36e-041461505159dd157a74f3c27dc1a1dcbbf0ed8f9462cac9e
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Chrm2_(Cerebellum_basket_cells_4)|Cerebellum / BrainAtlas - Mouse McCarroll V32

LCT GPX6 FUT1 SERPINF2

1.54e-0480150454f520cca126810510479fbeade2e3f66fb5dd1b
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb-Inhibitory_Neuron.Gad1Gad2.Pvalb-Chrm2_(Cerebellum_basket_cells_4)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

LCT GPX6 FUT1 SERPINF2

1.54e-04801504ce38ea123853a1e1082a033fb779b63ea440661d
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-glomerular_mesenchymal_cell-Mesangial_Cell-mesangial_typical|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

EDNRA PIEZO2 ADRA2B COL21A1 AGTR1

1.55e-0415015058645b9c7f9511ed6cc9afe04440c2873a3094150
ToppCelldroplet-Liver-nan-3m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO3 F12 SLC25A13 SERPINF2 G6PC1

1.59e-041511505cc9632b58522e2ba3ad36a0b8d37c7c9c8b636c4
ToppCelldroplet-Liver-Hepatocytes-24m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1RL LGALS4 SERPING1 SERPINF2 G6PC1

1.64e-041521505c21e2152b0130485659051d8fb7fb4589d1ec997
ToppCellfacs-Liver-Hepatocytes|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

C1RL F12 ABCB4 ABCC2 G6PC1

1.86e-041561505e2cda3ad4e5f44a80133864c5a38b766afb952ce
ToppCell367C-Lymphocytic-ILC|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

ABCC4 FMO3 MARVELD1 ABCB5 SERPINF2

1.91e-041571505f511871e1a004c6e9af08ee325ab1bfc41807487
ToppCelldroplet-Liver-HEPATOCYTES-1m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F12 GSTM1 SERPING1 SERPINF2 G6PC1

1.97e-0415815059f58428f70d1427b20122c5c1cc7bf521d0f4832
ToppCellICU-NoSEP-Lymphocyte-T_NK-Treg|ICU-NoSEP / Disease, Lineage and Cell Type

SGPP2 GPX3 THSD1 USP9Y ABCC2

2.03e-041591505d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FMO3 CSMD2 LGALS4 DDX60L LTB4R

2.09e-041601505636127753e3a22831f39d4c8170df40901e4329d
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO3 F12 SERPING1 SERPINF2 G6PC1

2.09e-0416015058de1fc75241d9bf2b355afa0e9ef39fea1977177
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

FMO3 CSMD2 LGALS4 DDX60L LTB4R

2.09e-041601505cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCellNS-critical-d_16-33-Myeloid-Mast_cell|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

ABCC4 SH2D4B GRAP2 LTC4S CHRFAM7A

2.09e-041601505c61869d9dbba250270e59366e15af204e5b4395d
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO3 F12 SERPING1 SERPINF2 G6PC1

2.15e-041611505274838cebdc7af1db32d309dfe42ef7ccd3c190b
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial-hepatocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO3 F12 SERPING1 SERPINF2 G6PC1

2.27e-04163150503d9fa615d9d02ef98e20f28a10aaa6894dd4960
ToppCelldroplet-Liver-Hepatocytes-18m-Epithelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO3 F12 SERPING1 SERPINF2 G6PC1

2.27e-0416315051c4de36cf8cdaabb981cda5c7ce7e5ae7b4280e3
ToppCelldroplet-Liver-Hepatocytes-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FMO3 F12 SERPING1 SERPINF2 G6PC1

2.27e-0416315057e82c1b7849eca895732df2da74ac6430bd9ba7a
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA GPX3 GSTM1 FUCA2 SERPINF2

2.41e-041651505906321cb5f299d77436fb5540fd8c52d7532beca
ToppCellfacs-Kidney-nan-24m-Epithelial-epithelial_cell_of_proximal_tubule|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA GPX3 GSTM1 FUCA2 SERPINF2

2.41e-04165150502a09d0918b103aca21c36b42c5a8a8ebad8686c
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NAPSA CFTR LDLR CPNE1 HERC3

2.47e-041661505575c325db88d6909cdf0d5e664bd9098b89d4401
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPX3 F12 GSTM1 SERPING1 G6PC1

2.54e-0416715053e3d8f6df2feefafad5b44ba0ebf5b5a0fe4ed58
ToppCellfacs-Heart-RV-24m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPX3 F12 GSTM1 SERPING1 G6PC1

2.54e-0416715053ad9f3122dbe96580f640388ef920ea209fc2349
ToppCellfacs-Heart-RA-24m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA SGPP2 GPR55 BLK GRAP2

2.69e-041691505dcf92121fb00e3b6498e2648363e90ac044ea396
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_1-Inh_L1_VIP_PRSS8|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

ABCB5 CHRNA7 KHDC3L CHRFAM7A PCSK9

2.69e-041691505876e666220a4041826dac313082fdd44da15b2b1
ToppCelldroplet-Fat-Gat-18m-Lymphocytic-B_cell|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPSA BLK ADRA2B RASGEF1B FUT1

2.76e-0417015055185187ecf26b4c9eaa0c01ad52697ab8d075cc7
DrugGlutathione

GPX3 GPX5 GSTM1 GSTM4 GPX6 LTC4S

1.18e-07361496DB00143
Drughydroxyrubicin

ABCC4 ABCB5 LCT ABCC2 TOP2B

3.43e-07231495CID000072398
Drugepicholesterol

HSD17B7 ABCA4 RHBDF1 ABCB5 GPX5 LCT LDLR CHRNA7 ABCB4 ADRB1 SCAP AGTR1 FUT1 ABCC2 CHRFAM7A G6PC1 PCSK9

9.71e-0763614917CID000000304
Drugarabinopyranose

SLC2A7 PGM2L1 ASIC5 LCT AGTR1 FUCA1 FUCA2 G6PC1 FGGY TOP2B XPR1

1.25e-0626114911CID000000229
Drugpheophytin

ABCC4 ABCB5 LCT ABCB4 GSTM1 GSTM4 SLC25A13 UGP2 LTC4S ABCC2 G6PC1

2.82e-0628414911CID000000250
Drugbupranolol

ABCB5 CFTR ABCB4 ADRA2B ADRB1 ACCS

3.55e-06631496CID000002475
Drugethacrynic acid

ABCC4 ABCB5 GPX5 EDNRA GSTM1 GSTM4 LTC4S ABCC2

3.61e-061381498CID000003278
Drug8-azido-ADP

ABCA4 ABCB5 CFTR ABCB4

3.92e-06171494CID000121934
Drugbenzbromarone

ABCC4 ABCB5 ABCB4 ABCC2 TOP2B

4.13e-06371495CID000002333
Drugverapamil

ABCC4 ABCA4 ABCB5 CFTR ASIC5 LDLR CHRNA7 EDNRA ABCB4 ADRA2B ADRB1 ABCC2 CHRFAM7A TOP2B

4.36e-0649014914CID000002520
Drug3-isoreserpine

ABCC4 ABCA4 ABCB5 LDLR EDNRA ABCB4 ADRA2B ADRB1 ABCC2

4.64e-061901499CID000005052
Drugsulfobromophthalein

ABCC4 ABCB5 ABCB4 GSTM1 GSTM4 LTC4S ABCC2

5.23e-061031497CID000005345
Drugv 104

ABCB5 ABCB4 ABCC2

5.41e-0661493CID000107262
DrugDigocin

ABCB5 CFTR ABCB4 AGTR1 ABCC2 TOP2B

6.59e-06701496CID000003062
Drugguanethidine

FMO3 WARS1 CHRNA7 ADRA2B ADRB1 AGTR1 CHRFAM7A

9.66e-061131497CID000003518
Drugamiodarone

ABCB5 CFTR ASIC5 LDLR ABCB4 ADRB1 FUCA1 FUCA2

1.07e-051601498CID000002156
Drugniguldipine

ABCB5 ABCB4 ADRB1 TOP2B XPR1

1.11e-05451495CID000001236
DrugAC1LCF1F

ABCC4 ABCB5 ABCB4 GSTM1 CLYBL UGP2 CPNE1 ABCC2

1.12e-051611498CID000627275
DrugBile Acids and Salts

ABCC4 CFTR MCL1 LDLR ABCB4 ABCC2

1.33e-05791496ctd:D001647
Drugaminotriazole

ABCB5 EIF3E GPX5 ABCB4 GSTM1 GSTM4 LTC4S CNOT1

1.47e-051671498CID000001639
DrugtBCEU

ABCB5 ABCB4 TOP2B

1.50e-0581493CID000164059
Drugnicotine glucuronide

ABCB5 ABCB4 ABCC2

1.50e-0581493CID003035848
DrugtXMP

ABCC4 ABCB5 ABCB4

1.50e-0581493CID003081384
Drugoxidized glutathione

ABCC4 ABCB5 CFTR GPX5 ABCB4 GSTM1 GSTM4 LTC4S ABCC2

1.94e-052271499CID000000975
DrugSo324

ABCC4 ABCB5 ABCB4

2.24e-0591493CID000462261
Drugstrychnine HCl

WARS1 ASIC5 CHRNA7 GSTM1 GSTM4 LTC4S CHRFAM7A TOP2B

2.62e-051811498CID000005304
DrugAtorvastatin Calcium

MCL1 LDLR EDNRA ABCB4 SGK2 ABCC2 G6PC1 EIF2AK3

3.19e-051861498ctd:D000069059
DrugAC1Q5QI1

EDNRA AGTR1 ABCC2

3.19e-05101493CID000186002
DrugAC1MZ4R5

ABCB5 ABCB4 TOP2B

3.19e-05101493CID003842392
DrugTexas Red

ABCC4 ABCB5 CFTR ABCC2

3.19e-05281494CID000452705
Drugoltipraz

ABCC4 MCL1 GSTM1 GSTM4 ABCC2

3.28e-05561495ctd:C026209
Drugvinblastine

ABCC4 ABCB5 CFTR CHRNA7 ABCB4 ABCC2 CHRFAM7A TOP2B

3.57e-051891498CID000013342
DrugSR-12813

ABCB5 LDLR LGALS4 SCAP

3.68e-05291494CID000446313
Drugfluvastatin

MCL1 LDLR SGK2 ABCC2 G6PC1 PCSK9

3.82e-05951496ctd:C065180
DrugAC1L9E0Q

ABCC4 ABCB5 ABCB4 ABCC2

4.23e-05301494CID000443095
Drugamphimedine

CFTR TOP2B

4.25e-0521492CID000100819
Drugoxoaporphine

CFTR TOP2B

4.25e-0521492CID000326183
Drugbenzyl-beta-lactoside

CFTR LCT

4.25e-0521492CID003462525
DrugFL4c

FUCA1 FUCA2

4.25e-0521492CID000124915
DrugS)-cotinine

HSD17B7 FMO3 CHRNA7 GSTM1 ACCS CHRFAM7A

4.30e-05971496CID000000408
DrugnorUDCA

ABCC4 LDLR ABCB4

4.36e-05111493CID000192254
Drug6-methylpurine-2'-deoxyriboside

ABCC4 ABCB5 ABCB4 ABCC2 TOP2B

4.97e-05611495CID000097184
Drugivermectin

ABCB5 CFTR CHRNA7 ABCB4 ABCC2 CHRFAM7A

5.40e-051011496CID006435110
DrugAC1L8YYB

ABCC4 ABCB5 ABCC2 TOP2B

7.01e-05341494CID000435167
DrugAC1L85AO

ABCC4 ABCB5 ABCB4 ABCC2 TOP2B

7.27e-05661495CID000372705
DrugAC1L1AUV

ABCB5 ABCB4 TOP2B

7.49e-05131493CID000051323
DrugMDL 25,637

LCT FUCA1 FUCA2

7.49e-05131493CID000128548
DrugDixan

PDLIM5 GSTM1 GSTM4 LTC4S

7.88e-05351494CID000010404
Drugoctopamine

CFTR LGALS4 ADRA2B ADRB1 FUCA1 FUCA2

8.26e-051091496CID000004581
Drugaminals

FUCA1 FUCA2 G6PC1

9.48e-05141493CID000075408
DrugAD 288

ABCB5 ATM TOP2B

9.48e-05141493CID000073553
Drugrobinetin

ABCB5 ABCB4 ABCC2

9.48e-05141493CID005281692
Drugtetramethylrosamine

ABCC4 ABCB5 ABCC2

9.48e-05141493CID000443313
DrugAC1L1TSE

ABCC4 ABCB5 ABCB4 LTB4R ABCC2

1.10e-04721495CID000060719
DrugPAK-104P

ABCC4 ABCB5 ABCC2

1.18e-04151493CID000131368
DrugAC1OAGYH

LCT FUCA1 FUCA2

1.18e-04151493CID006857622
Drug1, 3-diallylurea

ABCB5 ASIC5 BLK SERPINF2 TOP2B

1.26e-04741495CID000074537
Drugstilbene oxide

ABCB4 GSTM1 GSTM4 UGP2 LTC4S

1.26e-04741495CID000028649
Drugfluoroanilinoazatoxin

ABCB5 TOP2B

1.27e-0431492CID000378896
DrugNSC688503

ABCB5 TOP2B

1.27e-0431492CID000390744
DrugBIBW22BS

ABCB5 TOP2B

1.27e-0431492CID000132088
DrugAC1NSGRQ

ABCB5 CFTR

1.27e-0431492CID005333904
Drugneoeriocitrin

PDLIM5 SERPINF2

1.27e-0431492CID000114627
DrugS-(2,4-dinitrophenyl)glutathione

ABCC4 ABCC2

1.27e-0431492ctd:C030190
Drugmethylazatoxin

ABCB5 TOP2B

1.27e-0431492CID000148162
DrugAC1MHUMP

LDLR LGALS4

1.27e-0431492CID003011702
DrugWp159

ABCB5 TOP2B

1.27e-0431492CID003060549
DrugEthoxyquin

ABCC4 GSTM1 GSTM4 ABCC2

1.34e-04401494ctd:D005015
DrugEUK-189

GPX3 GSTM1 GSTM4

1.44e-04161493ctd:C436526
DrugAC1L4BIC

ABCC4 ABCB5 ABCC2

1.44e-04161493CID000153998
DrugNSC 284682

ABCB5 ABCB4 TOP2B

1.44e-04161493CID000072518
DrugGsts

RAN ABCC4 GPX5 GSTM1 GSTM4 LTC4S ABCC2

1.47e-041731497CID000128079
DrugAC1Q6O8B

ABCC4 LDLR ABCB4 ABCC2

1.48e-04411494CID000000334
Drugprobenecid

ABCC4 ABCB5 ABCB4 CLYBL ABCC2 TOP2B

1.61e-041231496CID000004911
DrugAC1L1J6H

ABCB5 MCL1 LDLR ABCB4 SCAP ABCC2 ADIPOR2 PCSK9

1.68e-042361498CID000004889
DrugPgh1

ABCB5 CFTR ABCB4

1.75e-04171493CID005283048
DrugBAY u9773

ABCC4 LTC4S LTB4R

1.75e-04171493CID005071481
Drugmannosylamine

GRAP2 FUCA1 FUCA2

1.75e-04171493CID000192844
Drugantibiotic G 418

CFTR ATM ABCC2

1.75e-04171493ctd:C010680
DrugAC1LAR6M

FUCA1 FUCA2 TOP2B

1.75e-04171493CID000493588
DrugNSC91998

ABCC4 ABCB5 ABCB4 ABCC2 TOP2B

1.93e-04811495CID000005668
Drugtalinolol

ABCB5 ADRB1 ABCC2

2.09e-04181493CID000068770
Drugcoproporphyrin I

PDLIM5 ABCB4 ABCC2

2.09e-04181493CID000068271
Drughydroxylamine

FMO3 GPX5 ASIC5 GSTM1 GSTM4 SERINC1 LTC4S TOP2B

2.11e-042441498CID000000787
Drug4-epidoxorubicin

ABCC4 ERCC3 ABCB5 ARL6IP5 CFTR TSPYL2 GPX5 MCL1 ABCB4 GSTM1 GSTM4 LTC4S ATM ABCC2 TOP2B

2.12e-0478814915CID000001690
Drugamsacrine

ABCC4 ABCB5 ABCC2 TOP2B

2.13e-04451494CID000002179
DrugFructose

SLC2A7 LCT LDLR EDNRA AGTR1 G6PC1 EIF2AK3 ADIPOR2

2.23e-042461498ctd:D005632
Drugzinc chloride (ZnCl2

NAPSA CFTR F12 GSTM1 GSTM4 LTC4S PCSK9

2.29e-041861497CID000005727
Drugdocetaxel

ABCC4 ABCA4 FMO3 MCL1 ABCB4 ABCC2

2.46e-041331496ctd:C067311
DrugApa-sg

ABCC4 ABCB5 ABCC2

2.46e-04191493CID000126348
DrugP-113

EDNRA ADRA2B AGTR1 SERPING1

2.52e-04471494CID000036736
Druglacto-N-hexaose

FUCA1 FUCA2

2.53e-0441492CID000194173
DrugAC1L3B2K

PDLIM5 SERPINF2

2.53e-0441492CID000086193
DrugBBR 2378

ABCB5 TOP2B

2.53e-0441492CID000219053
DrugD-arabinono-1,4-lactone

FUCA1 FUCA2

2.53e-0441492CID000017723
Drug9-methylphenazine-1-carboxylic acid

ABCB5 TOP2B

2.53e-0441492CID004037810
Drug1,3,4-trideoxynojirimycin

FUCA1 FUCA2

2.53e-0441492CID000636936
DrugANA 2000

WARS1 LCT

2.53e-0441492CID006336581
Drugbromonitromethane

FUCA1 FUCA2

2.53e-0441492CID000068423
DrugNK-252

ABCB5 TOP2B

2.53e-0441492CID000130889
Diseasecystic fibrosis (implicated_via_orthology)

ABCC4 ABCB5 CFTR ABCB4

6.73e-0891444DOID:1485 (implicated_via_orthology)
Diseasemacular degeneration (is_implicated_in)

ABCA4 GSTM1 ADIPOR1 SERPING1

8.75e-06271444DOID:4448 (is_implicated_in)
Diseasecholestasis (implicated_via_orthology)

ABCB4 GSTM1 ABCC2

9.36e-0691443DOID:13580 (implicated_via_orthology)
DiseaseHereditary angioneurotic edema

F12 SERPING1

2.37e-0521442cv:C0019243
Diseaseangioedema (is_implicated_in)

F12 SERPING1

2.37e-0521442DOID:1558 (is_implicated_in)
Diseasehyperinsulinism (biomarker_via_orthology)

ADIPOR1 AGTR1 ADIPOR2

4.96e-05151443DOID:2018 (biomarker_via_orthology)
DiseaseAngioedemas, Hereditary

F12 SERPING1

7.07e-0531442C0019243
Diseasecholestasis (biomarker_via_orthology)

ABCC4 CFTR ABCB4 ABCC2

9.72e-05491444DOID:13580 (biomarker_via_orthology)
Diseasecomplement C1r subcomponent-like protein measurement

C1RL SERPING1

1.41e-0441442EFO_0801495
Diseasehereditary angioedema (is_marker_for)

F12 SERPING1

1.41e-0441442DOID:14735 (is_marker_for)
Diseaseintrahepatic cholestasis (implicated_via_orthology)

ABCB4 SLC25A13

1.41e-0441442DOID:1852 (implicated_via_orthology)
DiseaseCOVID-19 (is_implicated_in)

AGTR1 SERPING1 SERPINF2

1.42e-04211443DOID:0080600 (is_implicated_in)
Diseaselung disease (is_implicated_in)

CFTR EDNRA GSTM1

1.64e-04221443DOID:850 (is_implicated_in)
DiseaseFanconi Syndrome

GPX3 XPR1

2.34e-0451442C0015624
DiseaseBrugada syndrome (implicated_via_orthology)

GSTM1 GSTM4

2.34e-0451442DOID:0050451 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease (is_implicated_in)

CFTR CHRNA7 GSTM1 ADRB1

2.59e-04631444DOID:3083 (is_implicated_in)
Diseasefish consumption measurement

LIMK2 NF1 SLC25A13 CNOT1

2.75e-04641444EFO_0010139
Diseasehypertension (is_implicated_in)

FMO3 EDNRA ADRA2B ADRB1 AGTR1

3.26e-041211445DOID:10763 (is_implicated_in)
Diseasecognitive disorder (implicated_via_orthology)

CHRNA7 CHRFAM7A

3.50e-0461442DOID:1561 (implicated_via_orthology)
Diseaserheumatoid arthritis (biomarker_via_orthology)

CHRNA7 CHRFAM7A

3.50e-0461442DOID:7148 (biomarker_via_orthology)
Diseaseglycocholenate sulfate measurement

ADCK5 ABCC2

3.50e-0461442EFO_0800276
DiseaseNon-alcoholic Fatty Liver Disease

LDLR ABCB4 GSTM1 ABCC2

3.88e-04701444C0400966
DiseaseNonalcoholic Steatohepatitis

LDLR ABCB4 GSTM1 ABCC2

3.88e-04701444C3241937
DiseaseColorectal Neoplasms

ABCC4 ABCA4 ABCB5 CFTR ABCB4 GSTM1 ABCC2

4.38e-042771447C0009404
Diseasediastolic blood pressure, systolic blood pressure

GPX3 MCL1 F12 PDLIM5 EDNRA PIEZO2 CLYBL COL21A1 CNEP1R1 LTC4S FGGY

4.67e-0467014411EFO_0006335, EFO_0006336
Diseaselung cancer (is_implicated_in)

CFTR MCL1 CHRNA7 GSTM1

4.80e-04741444DOID:1324 (is_implicated_in)
DiseaseLDL cholesterol change measurement

LDLR PCSK9

4.89e-0471442EFO_0007804
Diseasehereditary lymphedema (is_implicated_in)

PIEZO1 THSD1

4.89e-0471442DOID:0050580 (is_implicated_in)
Diseasehereditary angioedema (is_implicated_in)

F12 SERPING1

4.89e-0471442DOID:14735 (is_implicated_in)
Diseasecomplement C1r subcomponent measurement

C1RL SERPING1

4.89e-0471442EFO_0008090
Diseaseperiodontitis (is_implicated_in)

GSTM1 ADRB1

4.89e-0471442DOID:824 (is_implicated_in)
Diseasefatty liver disease (biomarker_via_orthology)

ABCC2 G6PC1 ADIPOR2

5.58e-04331443DOID:9452 (biomarker_via_orthology)
Diseaselung non-small cell carcinoma (is_implicated_in)

ERCC3 MCL1 CHRNA7 ATM ABCC2

6.15e-041391445DOID:3908 (is_implicated_in)
DiseaseCholestasis of pregnancy

ABCB4 ABCC2

6.50e-0481442C0268318
DiseaseFamilial hypercholesterolemia

LDLR PCSK9

6.50e-0481442cv:C0020445
DiseaseDrug Allergy

GSTM1 LTC4S ABCC2

6.64e-04351443C0013182
Diseasedifferentiated thyroid carcinoma

TRMO FAF1 PCNX2

6.64e-04351443EFO_1002017
Diseaserenovascular hypertension (implicated_via_orthology)

ADRB1 AGTR1

8.33e-0491442DOID:1591 (implicated_via_orthology)
DiseaseDegenerative Diseases, Central Nervous System

GPX3 GSTM1 GSTM4

9.15e-04391443C0270715
Diseasethyroid carcinoma

TRMO PCNX2 CNEP1R1

9.15e-04391443EFO_0002892
DiseaseNeurodegenerative Disorders

GPX3 GSTM1 GSTM4

9.15e-04391443C0524851
DiseaseDegenerative Diseases, Spinal Cord

GPX3 GSTM1 GSTM4

9.15e-04391443C0751733
Diseaseaspirin use measurement

LDLR EDNRA PCSK9

9.15e-04391443EFO_0007013
Diseasecholesterol in very small VLDL measurement

LDLR FUT1 PCSK9

9.85e-04401443EFO_0022231
Diseasefamilial hypercholesterolemia (is_implicated_in)

LDLR PCSK9

1.04e-03101442DOID:13810 (is_implicated_in)
Diseaseadseverin measurement

C1RL CPNE1

1.04e-03101442EFO_0801358
Diseasesenile cataract (is_implicated_in)

GSTM1 ATM

1.26e-03111442DOID:9669 (is_implicated_in)
Diseaseobstructive sleep apnea (is_implicated_in)

EDNRA ADRB1

1.26e-03111442DOID:0050848 (is_implicated_in)
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

GPX3 CHRNA7 GSTM1

1.39e-03451443DOID:3748 (is_implicated_in)
Diseasenicotine dependence (implicated_via_orthology)

CHRNA7 CHRFAM7A

1.51e-03121442DOID:0050742 (implicated_via_orthology)
Diseasepapillary thyroid carcinoma

TRMO PCNX2

1.51e-03121442EFO_0000641
Diseaseaspartate aminotransferase measurement

MCMBP ABCA4 PIEZO1 MCL1 LCT ABCB4 GSTM1 BLK ADRB1 NF1 CPNE1 ABCC2

1.64e-0390414412EFO_0004736
Diseasetotal lipids in lipoprotein particles measurement

LDLR FUT1 PCSK9

1.68e-03481443EFO_0022309
Diseasetotal cholesterol measurement, triglyceride measurement, low density lipoprotein cholesterol measurement, high density lipoprotein cholesterol measurement

ADRB1 NF1 ZC3H12C

1.78e-03491443EFO_0004530, EFO_0004574, EFO_0004611, EFO_0004612
Diseaseapolipoprotein B to apolipoprotein A1 ratio

LDLR GSTM1 PCSK9

1.78e-03491443EFO_0021897
Diseaseesophageal cancer (is_implicated_in)

GPX3 GSTM1

1.78e-03131442DOID:5041 (is_implicated_in)
Diseaseatherosclerosis

LDLR EDNRA

1.78e-03131442EFO_0003914
DiseaseSarcoma, Spindle Cell

MCL1 NF1

2.07e-03141442C0205945
DiseaseSarcoma, Epithelioid

MCL1 NF1

2.07e-03141442C0205944
Diseaseresponse to statin, LDL cholesterol change measurement

LDLR PCSK9

2.38e-03151442EFO_0007804, GO_0036273
DiseaseColorectal Carcinoma

ABCC4 ABCA4 ABCB5 CFTR ABCB4 GSTM1 LIFR NF1 ABCC2 PIGO

2.41e-0370214410C0009402
DiseaseAntithrombotic agent use measurement

LDLR EDNRA PCSK9

2.48e-03551443EFO_0009925
Diseaseleukemia

GSTM1 NF1 ATM

2.48e-03551443C0023418
Diseasefree cholesterol to total lipids in large HDL percentage

LDLR GSTM1 PCSK9

2.61e-03561443EFO_0022279
Diseaselevel of Sterol ester (27:1/18:1) in blood serum

LDLR PCSK9

2.71e-03161442OBA_2045195
Diseaseirritable bowel syndrome symptom measurement

CHRNA7 DDX60L CHRFAM7A

2.89e-03581443EFO_0021536
Diseaselow density lipoprotein particle size measurement

LDLR GSTM1 PCSK9

2.89e-03581443EFO_0008593
Diseaselevel of Sphingomyelin (d34:1) in blood serum

LDLR PCSK9

3.44e-03181442OBA_2045175
Diseasenon-alcoholic fatty liver disease (is_implicated_in)

ABCC2 ADIPOR2

3.44e-03181442DOID:0080208 (is_implicated_in)
DiseaseHypercholesterolemia, Familial

LDLR PCSK9

3.44e-03181442C0020445
Diseaseanorectal malformation

CSMD2 SUSD5

3.83e-03191442MONDO_0019938
DiseaseAlopecia

EDNRA ABCC2

3.83e-03191442C0002170
Diseasetype 2 diabetes mellitus (is_marker_for)

GPX3 F12 FUCA1 G6PC1

4.51e-031361444DOID:9352 (is_marker_for)
DiseaseBenign Neoplasm

GPX3 GPR55 ATM

4.52e-03681443C0086692
DiseaseNeoplasms

GPX3 GPR55 ATM

4.52e-03681443C0027651
Diseasehyperglycemia (biomarker_via_orthology)

ADIPOR1 ADRB1

4.67e-03211442DOID:4195 (biomarker_via_orthology)
DiseaseSarcoma

MCL1 NF1

4.67e-03211442C1261473
Diseaseesophagus adenocarcinoma (is_implicated_in)

GPX3 GSTM1

4.67e-03211442DOID:4914 (is_implicated_in)
Diseasecholesteryl esters to total lipids in chylomicrons and extremely large VLDL percentage

LDLR PCSK9

4.67e-03211442EFO_0022246

Protein segments in the cluster

PeptideGeneStartEntry
CWLPFFLANVVKAFH

ADRB1

336

P08588
IILLHVFWGIVFFDG

APH1B

166

Q8WW43
GKIWPLFPVFHQFLE

DCUN1D4

226

Q92564
TPFLPADETFWKHFL

CCRL2

186

O00421
FDEGLALAHFVWIAP

CFTR

191

P13569
WKIALPVGFGAHIQF

CSMD2

1996

Q7Z408
KWNFSVGHFELRYIP

EIF2AK3

256

Q9NZJ5
SANPFHWDLIGKNLF

ABCA4

1866

P78363
HFQGFWRNKFDPSLT

SERPINF2

236

P08697
KEPGWFRFVFSDQVH

ACCS

451

Q96QU6
KQFFHSVLAQDIGWF

ABCB5

141

Q2M3G0
FSWIPHQIFTFLDVL

AGTR1

251

P30556
VHDIRWNFEKFLVGP

GPX3

176

P22352
CKVPHGLFQFFFWIG

ADRA2B

401

P18089
INVFKLLAGRWPFDH

EDNRA

136

P25101
WPFDHNDFGVFLCKL

EDNRA

146

P25101
HPSFGFSWVLQDLKG

ADCK5

256

Q3MIX3
SFLFALIWGFGAHLP

DNHD1

2286

Q96M86
LGVTNPFFIKTLQHW

DENND6B

331

Q8NEG7
WFPFDVQHCKLKFGS

CHRNA7

156

P36544
PEEIQWFADKFSFHL

CLYBL

141

Q8N0X4
LSHWPFFDAFRKFLT

DENND4A

316

Q7Z401
VFHTNRGPIKFNVWD

RAN

51

P62826
FFPGKCDIWFHSHQL

ADIPOR2

336

Q86V24
IFFKIWPLSDFGFLR

IMMP1L

141

Q96LU5
AFHFNPRFDGWDKVV

LGALS4

61

P56470
FFFNPLHLCSWIKDE

CFAP99

121

D6REC4
SMHLWVGFPFFAVFL

OR52E1

21

Q8NGJ3
WSQVAEFIILGFPHL

OR6N1

6

Q8NGY5
DFFLLLGFSNWPHLE

OR2J1

11

Q9GZK6
LGFSNWPHLEVVLFV

OR2J1

16

Q9GZK6
FPGKFDIWFQSHQIF

ADIPOR1

326

Q96A54
LSFHWKPGQFVFKGD

KIAA0100

1171

Q14667
EFTGIDNLWGIHPFF

MDN1

1696

Q9NU22
VVGRLQKPCFFFHWL

FMO3

501

P31513
FGFPENWKEHIDNFL

MIS18BP1

461

Q6P0N0
DGAVHWLTNFIIGFL

SLC2A7

421

Q6PXP3
FREWFSKPANLHGVI

MTMR10

631

Q9NXD2
FGLNVKLFWEKFVPT

LIMK2

556

P53671
TEWVHFFQKLDPFLA

KIAA1755

716

Q5JYT7
TVKLFWETFHEFPLE

HERC3

961

Q15034
KSWALFHLEEPNIAF

KIAA1109

4676

Q2LD37
TKHFPEFSQILWIGG

DDX55

106

Q8NHQ9
LGVKSFKWGQNLHFF

DDX60L

51

Q5H9U9
FGKHWFNLNSLLAGP

ATXN3L

126

Q9H3M9
WLKYFPIEQFHVVDG

HS3ST5

241

Q8IZT8
WGSSFHVFAQLFAIP

PCNX2

1301

A6NKB5
IHFSAKDVINEAWFP

PCSK9

416

Q8NBP7
PLFLATLWVAGIFFH

LTC4S

61

Q16873
AWIGGFLHSLVQFLF

OR4A15

176

Q8NGL6
LTSFPGLEGIKHWIF

OR51M1

26

Q9H341
GLEGIKHWIFIPFFF

OR51M1

31

Q9H341
GLEDVHIWIGFPFFS

OR52E6

21

Q96RD3
YIWPFGNHSVDKFLA

OR4K17

261

Q8NGC6
EGFHFEETLPGFKWI

PGM2L1

401

Q6PCE3
AKFGVFIHWGVFSVP

FUCA1

56

P04066
HYKVFLSWAQLLPAG

LCT

86

P09848
LPFHLIFFGTAQNFW

KNTC1

1591

P50748
LPDTFIVNAKSAWFH

GABRD

121

O14764
GLAQGIFVFIAHFWS

ABCC2

1031

Q92887
FLVALGKSWHPEEFN

PDLIM5

431

Q96HC4
PHFTWLQAVFTNFPV

OC90

61

Q02509
RLPNGHVNFEKFWEL

RASGEF1B

391

Q0VAM2
TWSAKVFFPLEVFGF

GPR55

176

Q9Y2T6
WFPFDVQHCKLKFGS

CHRFAM7A

66

Q494W8
AEGWFHLFDLTPAKV

ITFG2

86

Q969R8
APFFLHFLAQGTWSF

LTB4R

71

Q15722
VAFFLLQGAWPHEGF

KIR2DS5

11

Q14953
QKFFHAILRQEIGWF

ABCB4

151

P21439
DQVTVFLHFLWAGPL

ABCC4

206

O15439
LPAWFDQAKFGIFIH

FUCA2

46

Q9BTY2
DQAKFGIFIHWGVFS

FUCA2

51

Q9BTY2
GQFLTVIGAFWHLTK

ATM

1016

Q13315
FFFILHFWVTILPAK

DEFB110

6

Q30KQ9
GHFFDLPDFLSWKAT

FGGY

166

Q96C11
LFPIWFHLQEAVGIK

G6PC1

46

P35575
PANIIWHFKEDGTIF

GALNT4

526

Q8N4A0
WTAPEAIHFGVFTIK

BLK

401

P51451
AKLGNFPWQAFTSIH

C1RL

251

Q9NZP8
FANPQVKTLFDEGWH

COL21A1

336

Q96P44
KLPELDWFLQHFAIS

DNAAF9

701

Q5TEA3
LGVTNPFFAKTLQHW

DENND6A

351

Q8IWF6
AVAKFGVIFFLWHIV

ASIC5

121

Q9NY37
HWSLFVFFNHPKGRD

EIF3E

216

P60228
PYNGTEALVWLFHQK

HSD17B7

261

P56937
PFLFVLWDQQHKFPV

SERPING1

476

P05155
GPVHFALFVSVLFWL

MARVELD1

56

Q9BSK0
FSWFHSEFLKNPKVV

KHDC3L

31

Q587J8
IGGADHSVFQWKFIP

EML5

581

Q05BV3
LWVAPDGHIFLEAFS

ERCC3

76

P19447
LQIVFDFVASKGFPW

FAF1

596

Q9UNN5
LHEGLSKPVYVINWF

FAM104B

81

Q5XKR9
VHDIRWNFEKFLVGP

GPX5

176

O75715
VHDIRWNFEKFLVGP

GPX6

176

P59796
IDIQFPKWFHEGLSR

GRAP2

51

O75791
SVFPWHKNLLAVDVF

SCAP

101

Q12770
LGFHLEFHWFIPTEF

SLC38A9

336

Q8NBW4
FLEFFRQGDGKWHLV

CPNE1

161

Q99829
LSWHLPGNFAKINFL

LIFR

451

P42702
LVKQRGWDGFVEFFH

MCL1

306

Q07820
DWLSHPLGIVQGFFA

MCMBP

6

Q9BTE3
GLEDVHVWIGFPFFA

OR52E5

21

Q8NH55
SLLFWKVHHLFLEGF

SND1-IT1

56

Q9HBX3
FEPQLLRFFHKNEIW

F12

136

P00748
FLKLSGFPCSWTFFH

FUT1

161

P19526
WFAVHSFGLDKAPVL

PTGFRN

731

Q9P2B2
RLTVLLPGHWVFFFS

RTL1

961

A6NKG5
VGHLIPFIFTKWLQD

WARS1

171

P23381
WVFSQLIKIFHSLGP

SYN3

206

O14994
EKLLPHIWGNVGFVF

RPLP0P6

76

Q8NHW5
KHLFWFPAEAFHKPG

SUSD5

291

O60279
HVKRWFGFLEAQQAF

EPRS1

146

P07814
EKDFPVWFGSVVGHI

TMC3

666

Q7Z5M5
QKVQFSWLFFAGAIP

SLC35F5

446

Q8WV83
IKNHVFFSPINWDDL

SGK2

286

Q9HBY8
NWPSLLKHGFLEEFI

TOP2B

581

Q02880
LPFLFFGHFWQLFNA

TMEM120A

276

Q9BXJ8
IAFPGKHFQEISWFL

RPL7L1

201

Q6DKI1
KHFQEISWFLCPFHL

RPL7L1

206

Q6DKI1
QHFSQFLGKRPWFVG

GSTM4

136

Q03013
PWFVGDKITFVDFLA

GSTM4

146

Q03013
VFTGFVWAAHNKDVL

ARL6IP5

76

O75915
PWFAGNKITFVDFLV

GSTM1

146

P09488
FHNIWDKLDGFVPAH

PTDSS2

186

Q9BVG9
FGLLPWIDNFAHISG

RHBDF1

761

Q96CC6
VLFGWPSLVFVFKNE

SLC43A3

26

Q8NBI5
FNIHFFQPDWKPESL

ST6GALNAC5

311

Q9BVH7
LEHFRLFFVTKVQWP

IQANK1

526

A8MXQ7
PFGIQFFLFLWIHVD

MRGPRX1

231

Q96LB2
QKVSFFTSLWNHPFF

CNEP1R1

56

Q8N9A8
DPRAAVHNGFWFFKF

SERINC1

116

Q9NRX5
GVTIGFWINHFFQLV

SGPP2

286

Q8IWX5
FWINHFFQLVSKPAE

SGPP2

291

Q8IWX5
PFNWDSEFVQLHFGK

SLC25A13

126

Q9UJS0
FIELIKNPAFKFWNH

CNOT1

2326

A5YKK6
FPTVNGLFRWFKDHY

SUPT6H

1501

Q7KZ85
VFTAPFHKVGFADFW

XPR1

381

Q9UBH6
LFHRFLQEKGPSVDW

UGP2

61

Q16851
GLEQFSHVWILFVFH

TRMO

76

Q9BU70
DLIIQHIPGFWVKAF

TSPYL2

256

Q9H2G4
FPKANITWFIDGSFL

CD96

296

P40200
HFWFLPNLTADVGFI

SEC62

261

Q99442
AFLKVEWPVFHVDLN

THSD1

121

Q9NS62
FWFSPAQFTGHIILS

SELENON

306

Q9NZV5
FIIIVFGFWAFGKHS

PIEZO2

2201

Q9H5I5
TDFLSKWFVVFPGFA

NF1

1656

P21359
LPQVFLKPWIFVEHF

KRT10-AS1

51

Q8N816
KLAWDFSPGQLDHLF

USP9Y

456

O00507
VFPAIHWHAAFVGFP

PIGO

911

Q8TEQ8
ERNTKFIAPWFHGII

SH2D4B

316

Q5SQS7
LFQFGFFPWNSHVVL

PIEZO1

1746

Q92508
DFIIIIFGFWAFGKH

PIEZO1

1971

Q92508
WFLERGHKDITVFVP

ZC3H12C

276

Q9C0D7
FHGTPVTIENFLNWK

RWDD1

141

Q9H446
AHQWLGPEFLTMFFF

VWA8

591

A3KMH1
TFHALFNQPLTPVFW

TRIM65

476

Q6PJ69
PWIDNIAHIFGFLSG

RHBDF2

766

Q6PJF5
EFGVGVNIFWKHLPS

TYW5

241

A2RUC4
LHFLKQDIPALSWEF

UNC79

1151

Q9P2D8
ITCGHFLVPFWTFFG

VMP1

276

Q96GC9
AHPFSLAVFEDKVFW

LDLR

606

P01130
LWEPSLVFAFAHFDG

NAPSA

171

O96009