Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
MousePhenoabnormal forebrain size

SETD2 WDFY3 CEP63

4.25e-0551193MP:0012137
MousePhenodecreased B-1b cell number

NLRP1 ZEB1

9.56e-0511192MP:0008170
DomainSOCS

RAB40A RAB40AL

2.72e-0420232SM00253
DomainSOCS_box

RAB40A RAB40AL

9.93e-0438232PF07525
DomainSOCS

RAB40A RAB40AL

1.05e-0339232PS50225
DomainSOCS_box

RAB40A RAB40AL

1.05e-0339232SM00969
DomainSOCS_box

RAB40A RAB40AL

1.05e-0339232IPR001496
DomainRAB

RAB40A RAB40AL

3.61e-0373232PS51419
DomainRas

RAB40A RAB40AL

1.20e-02136232PF00071
Domain-

NAV3 NLRP1 RAB40A RAB40AL

1.22e-027462343.40.50.300
DomainPH_dom-like

SNTG1 WDFY3 FRMD6

1.49e-02426233IPR011993
PathwayREACTOME_RAB_GERANYLGERANYLATION

RAB40A CHM RAB40AL

5.02e-0565163MM15511
Pubmed

Rab40b and Tks5 interact at invadopodia during metastasis.

RAB40A RAB40AL

4.95e-06525227909076
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

NAV3 NLRP1 WDFY3

5.37e-0510225310231032
Pubmed

Host-pathogen interactome mapping for HTLV-1 and -2 retroviruses.

WDFY3 CEP63

3.62e-043925222458338
Pubmed

The SOCS box: a tale of destruction and degradation.

RAB40A RAB40AL

4.00e-044125212076535
CytobandEnsembl 112 genes in cytogenetic band chrXq22

RAB40A RAB40AL

3.96e-03172252chrXq22
CytobandEnsembl 112 genes in cytogenetic band chr17p13

PER1 NLRP1

1.52e-02346252chr17p13
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD163+CD14+_DCs|normal_Pleural_Fluid / Location, Cell class and cell subclass

ZBTB5 NLRP1 SETD2 WDFY3

2.68e-061762547a74217b7fa1032b918f00a3972dff5fab74671a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 ZEB1 FRMD6 AFF3

3.71e-06191254bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 ZEB1 FRMD6 AFF3

3.71e-06191254107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-NK/T|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL1 CCDC136 AFF3

9.06e-0515725316581e2399a211633f870dce326c75ff4b6a5fe6
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL1 CCDC136 AFF3

9.06e-05157253cbb08d5c151f0622123276926a2a15bb7d271e90
ToppCelldroplet-Liver-Hepatocytes-24m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F2RL1 CCDC136 AFF3

1.01e-04163253924c666596bbb42d7876c9b164a725277f3efa5f
ToppCelltumor_Lymph_Node_/_Brain-T/NK_cells-CD8+/CD4+_Mixed_Th|T/NK_cells / Location, Cell class and cell subclass

PER1 WDFY3 CHM

1.21e-0417325342c911ed16fabdabef063830e8407192d8bde950
ToppCellkidney_cells-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.25e-0417525390302e8a44858ef3b2a165b88284d4788d591a99
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NLRP1 ZEB1 MUCL3

1.27e-0417625364e426f5e84884ce2c29acf6f4b958962a63927f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.52e-0418725335c382c0aabd46906113e5db30ea24bb8e658899
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

NAV3 ZEB1 FRMD6

1.52e-04187253bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellControl-Endothelial_cells-Endothelial_cells_(general)|Control / group, cell type (main and fine annotations)

NAV3 ZEB1 AFF3

1.52e-04187253fb5bcbc8effdbf0e57fcb71aca990a4aa0d65ce8
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV3 ZEB1 AFF3

1.54e-04188253117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCellASK428-Endothelial-Lymphatic|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

ZEB1 FRMD6 CCDC136

1.54e-04188253c371bc340966cfe9205cbf4b62c6452f49f2559f
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 ZEB1 FRMD6

1.54e-04188253ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

SETD2 ZEB1 CCDC136

1.59e-0419025391ba66d4b56c59523485b17738e93f14bb00afa4
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ZEB1 FRMD6 AFF3

1.59e-0419025370c86dd454afb21d4a85db56c5f369d4b342bc97
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D175|Adult / Lineage, Cell type, age group and donor

NAV3 ZEB1 FRMD6

1.59e-041902537dcca3469f3a3b70db0420cb94f7765f39492f06
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

PER1 SETD2 ZEB1

1.62e-041912531ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2-SCMF|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAV3 ZEB1 FRMD6

1.64e-0419225367e845e513e76e820f55e2f0d15eb16f2944d05c
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell|Adult / Lineage, Cell type, age group and donor

NAV3 ZEB1 FRMD6

1.64e-04192253d21f0f577156f17c899b08871046a26b88aea011
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 FRMD6 AFF3

1.64e-04192253d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.64e-04192253c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCellnucseq-Mesenchymal-Myocytic-Myocytic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAV3 ZEB1 FRMD6

1.67e-041932535de87fc94a6e58899ef4124cf4887ed3ff96163a
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary-CAP1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NAV3 ZEB1 AFF3

1.67e-04193253ad3f4fcc8e2816d696cbcde744dc16500e51ccac
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.67e-0419325352e918884877b6659cdca0496390e440f73694a9
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV3 ZEB1 AFF3

1.69e-0419425371ac69cdf7a08ca3ddfb5b492b14ac56b6cd5e5d
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

NAV3 ZEB1 AFF3

1.69e-0419425368004855b23fe1e31e8452d70effabc78a4a0bd3
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.69e-0419425374a9fdb73f279bebb6337510deab9aaaf9f7e957
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.69e-04194253e55dc30e200c9f576804acb642175eb4fa9146b5
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.69e-04194253a52c5906fce43c2f72cf7e463a3d15cde06431f6
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.74e-04196253adee900dcd16dbaba15c58bdcace09ba20214950
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.74e-04196253ab7be3858deabbd1fc44e8b9da8ff49a50bf1fb1
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.74e-0419625322767bcf0095d9eb0cbed7cdc74e4d32d9357e1b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.77e-041972530f467ef58f0c4dcc00b34b7b9639e03fb3ebe780
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_2|COVID-19_Mild / Disease condition and Cell class

PER1 NLRP1 NCOA4

1.77e-04197253e844f660010d114d65bd814f3d3fccd8e4a6b8da
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.77e-04197253cd509e49bbdbf991cc5913960ff3ef275ad40628
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.77e-04197253412cb5f37df57121ddd1492021445479c7cbccbf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.80e-04198253fa84bf8533d1b91d2c2bcf06b710670605072b89
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.80e-0419825307701c73137947ed4a27e225975329235bbb8734
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.80e-041982530a172c6d997c7cfbad34b56e80121bd104dee67d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NAV3 NLRP1 ZEB1

1.80e-0419825331ba87552be97c9b78c9e82f98e96699ccb19824
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NAV3 ZEB1 FRMD6

1.85e-0420025374e74123ea7bf38d337a3a0248a6a51437c6ab42
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Elfn1-Grik3_(Globus_Pallidus_Externus_(GP))-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MUCL3 MUC6

4.01e-04532527a962f43e74ca59f427a9081e6ea9c51fbaa624a
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Elfn1-Grik3_(Globus_Pallidus_Externus_(GP))|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MUCL3 MUC6

4.01e-04532528cbba4f6ef248d89dd494107dab656725f3d5e5d
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Elfn1-Grik3_(Globus_Pallidus_Externus_(GP))--|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

MUCL3 MUC6

4.01e-04532521568cca9fcf84ddf0f76abadf213f3a34ac1d0d2
Diseasesex interaction measurement, bilirubin measurement

FRMD6 F2RL1

1.33e-0422232EFO_0004570, EFO_0008343
Diseasecholesteryl ester 18:0 measurement

NLRP1 AFF3

3.60e-0436232EFO_0010343
Diseasecognitive impairment measurement

NAV3 CEP63

5.39e-0444232EFO_0007998
Diseasecannabis dependence measurement

ZEB1 AFF3

6.41e-0448232EFO_0008457
DiseasePapillary thyroid carcinoma

ZEB1 NCOA4

2.04e-0386232C0238463
Diseasehypertrophic cardiomyopathy

MUC6 CCDC136

2.33e-0392232EFO_0000538
DiseaseNeurodevelopmental Disorders

SETD2 WDFY3

2.38e-0393232C1535926
Diseasegastroesophageal reflux disease

NAV3 AFF3

2.80e-03101232EFO_0003948
Diseasebreast milk measurement

NCOA4 GOSR1

3.08e-03106232EFO_0009092
Diseaseimmature platelet count

SETD2 KIAA0232

3.08e-03106232EFO_0803544
Diseaselung disease severity measurement

SNTG1 AFF3

3.80e-03118232EFO_0007744
DiseasePapillary Renal Cell Carcinoma

NAV3 SETD2

4.45e-03128232C1306837
DiseaseRenal Cell Carcinoma

NAV3 SETD2

4.45e-03128232C0007134
DiseaseSarcomatoid Renal Cell Carcinoma

NAV3 SETD2

4.45e-03128232C1266043
DiseaseChromophobe Renal Cell Carcinoma

NAV3 SETD2

4.45e-03128232C1266042
DiseaseCollecting Duct Carcinoma of the Kidney

NAV3 SETD2

4.45e-03128232C1266044
Diseaseserum gamma-glutamyl transferase measurement

NLRP1 SETD2 ZEB1 MUC6

5.06e-03914234EFO_0004532
DiseaseConventional (Clear Cell) Renal Cell Carcinoma

NAV3 SETD2

5.90e-03148232C0279702
Diseasediabetic nephropathy

NAV3 AFF3

6.06e-03150232EFO_0000401

Protein segments in the cluster

PeptideGeneStartEntry
LKSSSETSVHCTSYR

AFF3

251

P51826
ASKHKYTSEDLTSSS

AFF3

886

P51826
SIRKKYCKVSSSSSS

CFAP97

161

Q9P2B7
KGTYLVHLTCTSSKT

CHM

501

P24386
YSLTTSSTHKSSLCK

RAB40A

241

Q8WXH6
YSLTTSSTHKRSSLC

RAB40AL

241

P0C0E4
TAKTSTSLPYHTSST

MUC6

1911

Q6W4X9
KLVSFSKLCTSYSHS

GOSR1

26

O95249
KSSSLSPYVKSSSSH

JHY

221

Q6NUN7
TTKRKCASSSSYTTS

PER1

646

O15534
NKSKVCSYSSSSSSS

KIAA0232

196

Q92628
TLTSKTTTTLCLHYL

NLRP1

541

Q9C000
YESCTSTKEATTSKH

NAV3

2321

Q8IVL0
KSSYQKCNSHSTTSS

NCOA4

266

Q13772
SKKHSRKSSSYSSSS

F2RL1

376

P55085
SYSSSAIHRKLKTCS

FRMD6

411

Q96NE9
SLTSYSLCKTHSLPS

CEP63

611

Q96MT8
TSAKTACLTSSSHKA

C1orf174

36

Q8IYL3
LDKTSTSSHKTTTSF

MUCL3

196

Q3MIW9
SIKLTCTLSSEHSTY

IGLV4-3

36

A0A075B6K6
ASTAASSATTSKAKY

SNTG1

501

Q9NSN8
TSSKSFLKSYDSSTS

CCDC136

781

Q96JN2
SQSSHLYKHSKTTCL

ZBTB5

651

O15062
KSSSSYHCSIIAMKT

WDFY3

471

Q8IZQ1
SKHDSSASRYKSTLS

SETD2

546

Q9BYW2
GSYSSHISSKKCISL

ZEB1

281

P37275