Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainSpectrin

SPTBN5 DST TRIO KALRN DMD

1.01e-0823615PF00435
DomainSpectrin_repeat

SPTBN5 DST TRIO KALRN DMD

3.51e-0829615IPR002017
DomainSpectrin/alpha-actinin

SPTBN5 DST TRIO KALRN DMD

5.92e-0832615IPR018159
DomainSPEC

SPTBN5 DST TRIO KALRN DMD

5.92e-0832615SM00150
DomainG-protein_beta_WD-40_rep

FBXW10B FBXW10 TBL1Y COPB2 TBL1XR1

8.44e-0685615IPR020472
DomainWD40_repeat_dom

KNTC1 FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

5.01e-05297617IPR017986
DomainActinin_actin-bd_CS

SPTBN5 DST DMD

5.60e-0523613IPR001589
DomainACTININ_2

SPTBN5 DST DMD

5.60e-0523613PS00020
DomainACTININ_1

SPTBN5 DST DMD

5.60e-0523613PS00019
DomainWD40

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

1.97e-04259616PF00400
DomainWD40

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

2.37e-04268616SM00320
DomainWD40_repeat

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

2.56e-04272616IPR001680
DomainWD_REPEATS_1

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

2.88e-04278616PS00678
DomainWD_REPEATS_2

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

2.94e-04279616PS50082
DomainWD_REPEATS_REGION

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

2.94e-04279616PS50294
DomainLisH

TBL1Y TBL1XR1

3.72e-049612PF08513
Domain-

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

7.47e-043336162.130.10.10
DomainWD40/YVTN_repeat-like_dom

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

7.71e-04335616IPR015943
DomainCH

SPTBN5 DST DMD

1.25e-0365613SM00033
DomainCH

SPTBN5 DST DMD

1.55e-0370613PF00307
Domain-

SPTBN5 DST DMD

1.62e-03716131.10.418.10
DomainCH

SPTBN5 DST DMD

1.75e-0373613PS50021
DomainKinase-like_dom

DST TRIO KALRN EIF2AK4 MAP3K15 PRKG2 DMD

1.87e-03542617IPR011009
DomainCH-domain

SPTBN5 DST DMD

1.89e-0375613IPR001715
DomainWD40_repeat_CS

FBXW10B FBXW10 TBL1Y TBL1XR1

2.03e-03164614IPR019775
DomainCRAL_TRIO

TRIO KALRN

2.12e-0321612PF00650
Domain-

TRIO KALRN

2.54e-03236123.40.525.10
DomainSEC14

TRIO KALRN

3.00e-0325612SM00516
DomainCRAL_TRIO

TRIO KALRN

3.49e-0327612PS50191
DomainLisH

TBL1Y TBL1XR1

3.76e-0328612SM00667
DomainLisH

TBL1Y TBL1XR1

3.76e-0328612IPR006594
DomainLISH

TBL1Y TBL1XR1

3.76e-0328612PS50896
DomainCRAL-TRIO_dom

TRIO KALRN

3.76e-0328612IPR001251
DomainSer/Thr_kinase_AS

TRIO KALRN EIF2AK4 MAP3K15 PRKG2

6.15e-03357615IPR008271
DomainKRAB

ZNF425 KRBA2 ZKSCAN7 ZNF227 ZNF891

6.22e-03358615PS50805
DomainKRAB

ZNF425 KRBA2 ZKSCAN7 ZNF227 ZNF891

6.22e-03358615PF01352
DomainS_TKc

TRIO KALRN EIF2AK4 MAP3K15 PRKG2

6.29e-03359615SM00220
DomainPROTEIN_KINASE_ST

TRIO KALRN EIF2AK4 MAP3K15 PRKG2

6.51e-03362615PS00108
DomainPH

SPTBN5 TRIO KALRN DGKK

6.65e-03229614PF00169
DomainDEAH_ATP_HELICASE

SMARCA1 YTHDC2

6.84e-0338612PS00690
DomainKRAB

ZNF425 KRBA2 ZKSCAN7 ZNF227 ZNF891

7.05e-03369615SM00349
DomainKRAB

ZNF425 KRBA2 ZKSCAN7 ZNF227 ZNF891

7.13e-03370615IPR001909
DomainPkinase

TRIO KALRN EIF2AK4 MAP3K15 PRKG2

8.04e-03381615PF00069
Pubmed

Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TCAF1 DST SV2A IPO13 TMEM63A

1.15e-061016359872452
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

DMXL2 SGIP1 DST TRIO NAPB KALRN SV2A RPS3A COPB2 YTHDC2 DMD OMG CACNA2D3

1.41e-061431631337142655
Pubmed

Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice.

FBXW10B FBXW10

3.23e-06263237450367
Pubmed

FBXW10 promotes hepatocarcinogenesis in male patients and mice.

FBXW10B FBXW10

3.23e-06263231400758
Pubmed

Kalirin and Trio proteins serve critical roles in excitatory synaptic transmission and LTP.

TRIO KALRN

3.23e-06263226858404
Pubmed

Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.

DST TRIO KALRN XPNPEP1 DMD

8.28e-0615163517043677
Pubmed

Synaptic Kalirin-7 and Trio Interactomes Reveal a GEF Protein-Dependent Neuroligin-1 Mechanism of Action.

TRIO KALRN

9.68e-06363231801062
Pubmed

Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.

DST DMD

1.93e-0546328954775
Pubmed

Assembly of high order G alpha q-effector complexes with RGS proteins.

TRIO KALRN

3.22e-05563218936096
Pubmed

FBXW10-S6K1 promotes ANXA2 polyubiquitination and KRAS activation to drive hepatocellular carcinoma development in males.

FBXW10B FBXW10

3.22e-05563237277019
Pubmed

Hepatic deficiency in transcriptional cofactor TBL1 promotes liver steatosis and hypertriglyceridemia.

TBL1Y TBL1XR1

3.22e-05563221459324
Pubmed

Structure of the MeCP2-TBLR1 complex reveals a molecular basis for Rett syndrome and related disorders.

TBL1Y TBL1XR1

4.82e-05663228348241
Pubmed

Two new susceptibility loci for Kawasaki disease identified through genome-wide association analysis.

COPB2 TECRL

4.82e-05663222446961
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

DMXL2 TCAF1 SGIP1 DST TRIO KALRN TBL1Y DZIP3 TBL1XR1

5.71e-0596363928671696
Pubmed

Zbtb7c is a molecular 'off' and 'on' switch of Mmp gene transcription.

TBL1Y TBL1XR1

6.74e-05763227646874
Pubmed

The nuclear receptor corepressor deacetylase activating domain is essential for repression by thyroid hormone receptor.

TBL1Y TBL1XR1

6.74e-05763215695367
Pubmed

A SUMOylation-dependent pathway mediates transrepression of inflammatory response genes by PPAR-gamma.

TBL1Y TBL1XR1

8.98e-05863216127449
Pubmed

Rett syndrome mutations abolish the interaction of MeCP2 with the NCoR/SMRT co-repressor.

TBL1Y TBL1XR1

8.98e-05863223770565
Pubmed

Genome-wide association study of co-occurring anxiety in major depression.

IL20RB DMD

1.44e-041063224047446
Pubmed

A corepressor/coactivator exchange complex required for transcriptional activation by nuclear receptors and other regulated transcription factors.

TBL1Y TBL1XR1

1.44e-041063214980219
Pubmed

Human transcription factor protein interaction networks.

MED24 DST TBL1Y ATXN7L1 RPS3A DGKK COPB2 SMARCA1 TAF2 TBL1XR1

2.33e-041429631035140242
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KNTC1 DMXL2 TCAF1 UTP14C TMEM63A PDZRN4

2.70e-0449363615368895
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

SPTBN5 DST RPS3A DMD

3.76e-0418763426460568
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

RPS3A CTNNA3 YTHDC2 EIF2AK4

5.62e-0420863433230847
Pubmed

Interactomes of Glycogen Synthase Kinase-3 Isoforms.

DST TRIO YTHDC2 DENND4C

5.72e-0420963436779422
Pubmed

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.

SV2A RPS3A RNASE7 MAP3K15 DMD

6.49e-0438263537249651
Pubmed

Diverse functions of myosin VI elucidated by an isoform-specific α-helix domain.

COPB2 YTHDC2

7.29e-042263226950368
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

MED24 DST SMC6 CCDC18 DZIP3 DENND4C

1.10e-0364563625281560
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

STARD13 KNTC1 DST DGKK SMARCA1 KRBA2 EIF2AK4 DMD UTP14C

1.11e-03144263935575683
Pubmed

The human SPT20-containing SAGA complex plays a direct role in the regulation of endoplasmic reticulum stress-induced genes.

SUPT20HL1 TAF2

1.18e-032863219114550
Pubmed

Mitochondrial Fission Factor Is a Novel Interacting Protein of the Critical B Cell Survival Regulator TRAF3 in B Lymphocytes.

SLC25A40 PRKG2

1.36e-033063234745083
Pubmed

A TFTC/STAGA module mediates histone H2A and H2B deubiquitination, coactivates nuclear receptors, and counteracts heterochromatin silencing.

SUPT20HL1 TAF2

1.36e-033063218206972
Pubmed

HENA, heterogeneous network-based data set for Alzheimer's disease.

DST TRIO DMD

1.37e-0312063331413325
Pubmed

NFX1-123 and poly(A) binding proteins synergistically augment activation of telomerase in human papillomavirus type 16 E6-expressing cells.

RPS3A DMD

1.55e-033263217267499
Pubmed

Human STAGA complex is a chromatin-acetylating transcription coactivator that interacts with pre-mRNA splicing and DNA damage-binding factors in vivo.

SUPT20HL1 TAF2

1.64e-033363211564863
Pubmed

Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.

TRIO KALRN DZIP3 YTHDC2 TBL1XR1

1.71e-0347563531040226
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

DST RPS3A COPB2 YTHDC2 XPNPEP1 DENND4C

1.77e-0370863639231216
Pubmed

BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.

DMXL2 DST SV2A VPS53

1.80e-0328563434369648
Cytoband12q12

ABCD2 PDZRN4

1.93e-034763212q12
Cytoband17p12

FBXW10B FBXW10

2.09e-034963217p12
GeneFamilyWD repeat domain containing

FBXW10B DMXL2 FBXW10 TBL1Y COPB2 TBL1XR1

2.22e-05262406362
GeneFamilyWD repeat domain containing|F-box and WD repeat domain containing

FBXW10B FBXW10

2.59e-0411402559
CoexpressionGSE44649_NAIVE_VS_ACTIVATED_CD8_TCELL_MIR155_KO_DN

SLC25A40 DZIP3 YTHDC2 TAF2 DENND4C BORA

7.89e-06200626M9777
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 CCDC18 KRBA2 PIF1 BORA

4.79e-06174635dbb4e1a6c3319ce40f81bfd2d1745a88a2cc412e
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBR3 SGIP1 DST KALRN LRRC70

6.62e-0618663540070d9cd20188ba49b32acfca9bc16256b38bf5
ToppCell3'_v3-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

DST CTNNA3 EIF2AK4 DMD CACNA2D3

6.80e-061876359f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCellRV-06._Ventricular_Cardiomyocyte_II|RV / Chamber and Cluster_Paper

DST CTNNA3 TECRL DMD CACNA2D3

7.34e-06190635fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 KALRN CTNNA3 DMD PDZRN4

7.53e-0619163504c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

TGFBR3 TCAF1 DST CTNNA3 DMD

9.19e-0619963538cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 KALRN CTNNA3 DMD PDZRN4

9.41e-06200635a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellAdult-Mesenchymal-chondrocyte-D122|Adult / Lineage, Cell type, age group and donor

SGIP1 TBL1Y CD79A CACNA2D3

5.76e-0514863481a1e6fdd942a612bf523c59b8b4974f6ca1fdce
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DGKK CTNNA3 DMD PDZRN4

6.39e-05152634bd1f36b436d8ab7dd8420f595b97d851eab31a38
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DGKK CTNNA3 DMD PDZRN4

6.39e-05152634ee329249a034a969a16b26a224aa04249d67382d
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

SGIP1 KALRN DMD PDZRN4

7.98e-0516163447b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellPND07-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KNTC1 CCDC18 CD79A PIF1

8.78e-05165634953c8242a81a39ade63ac8e5b34fe58575771746
ToppCellNS-critical-d_0-4-Epithelial-unknown_epithelial|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SPTBN5 KNTC1 ZNF425 RNASE7

8.98e-05166634dd02bbe4af609c6348dc92417254f4740f2900a8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DGKK SMC6 ZKSCAN7 ABCD2

9.85e-0517063428fb192b21cdc5a77ba4f276694cff852eb2304b
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 FBXW10 KALRN UTP14C

9.85e-05170634d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

DGKK SMC6 ZKSCAN7 ABCD2

9.85e-05170634239cb4b801b2d71a6facb386f2684c0851504151
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-ASMC|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

KALRN DMD CACNA2D3 PDZRN4

1.05e-04173634cb6389536195443633adb06e5f1b7483530773d1
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 CCDC18 PIF1 BORA

1.08e-041746347b318796728001c17b4043d2b033330c7be40c78
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTNNA3 KRBA2 DMD PDZRN4

1.10e-04175634d52794426f2703a80e91ae0a8ff2d8e0ce4aa4a8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN CTNNA3 DMD PDZRN4

1.10e-04175634316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CTNNA3 KRBA2 DMD PDZRN4

1.10e-04175634454f03e6109d65f5db08dbb41ecc19ffb6bbc4e0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN CTNNA3 DMD PDZRN4

1.10e-04175634a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

KNTC1 CCDC18 PIF1 BORA

1.10e-04175634876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-B_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHST4 CTNNA3 CD79A PRKG2

1.18e-04178634d3cbdec9d75f076e565baca05ede292cca7758a4
ToppCellControl-Fibroblasts-Airway_smooth_muscle|Control / group, cell type (main and fine annotations)

SGIP1 KALRN DMD PDZRN4

1.23e-04180634d0de12749ef0f51f0931c6e7b9b99966bdbc3ec1
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DZIP3 GPR162 OMG CFAP157

1.28e-04182634975f6275777fc578eba528e50f69891c66ec44ad
ToppCell368C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DZIP3 GPR162 OMG CFAP157

1.28e-04182634f8c28fa76751062c4cfba0db8af1b377f947f739
ToppCell5'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TGFBR3 SGIP1 DST KALRN

1.31e-041836344d16bfbadf2cd13008c35e23dd2b5b4ecf92ee11
ToppCellLV-15._Ventricular_Cardiomyocyte_III|LV / Chamber and Cluster_Paper

DST CTNNA3 TECRL DMD

1.34e-04184634ab7a1620c14a9d9b6be1b47c559931e345e9eef8
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TGFBR3 TCAF1 CTNNA3 DMD

1.36e-041856346712512100ccef456d2e2bd201d0987986c92ac9
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STARD13 DST CTNNA3 DMD

1.36e-04185634f607b6ee579562e2f92103fa5c7053df0170a229
ToppCell5'-Adult-LargeIntestine-Neuronal|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STARD13 DST CTNNA3 DMD

1.36e-04185634317f2c854f00aa5957319b818c85eeed7d72ec7f
ToppCell5'-Adult-LargeIntestine-Neuronal-Glial_mature-Adult_Glia|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STARD13 DST CTNNA3 DMD

1.36e-041856347bb8fdfe04f85d25056380ec58222366de323a21
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNA3 TECRL CACNA2D3 PDZRN4

1.39e-04186634337f768cc43db2db96ba6495b076006b1a5b0331
ToppCelldroplet-Liver-LIVER_HEP-30m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAPB SMARCA1 DZIP3 PRKG2

1.39e-04186634f5468e03321ea2083e223eb0d92c3a9307039569
ToppCellfacs-Heart-LA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNA3 TECRL CACNA2D3 PDZRN4

1.39e-04186634e378c82ef6d6cb24751515aa499a01372b3e7ccf
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

KALRN CTNNA3 DMD PDZRN4

1.39e-041866344780af76237d7af2abbe2d8d5530cdf53e3ed0b7
ToppCellCOVID-19-Fibroblasts-Airway_smooth_muscle|COVID-19 / group, cell type (main and fine annotations)

DST KALRN DMD PDZRN4

1.42e-04187634464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

TGFBR3 SGIP1 DST DMD

1.42e-04187634bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCell3'_v3-blood-Myeloid_Dendritic|blood / Manually curated celltypes from each tissue

DST CTNNA3 EIF2AK4 DMD

1.45e-04188634239a2162a21d3339da7c1884ab76286346fbf97f
ToppCellmulticiliated|World / shred by cell class for bronchial biopsy

DZIP3 GPR162 OMG CFAP157

1.45e-041886346833c1f0f265ef5448fa65033550ed7efc2f8d7b
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST SV2A CD79A PRKG2

1.45e-04188634a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell(7)_Epithelial_cells-(7)_Epithelial-F_(Ciliated)|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)

DZIP3 GPR162 OMG CFAP157

1.45e-041886345ba5cbb403518026e9040379fb5d99339ea977d8
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DZIP3 GPR162 OMG CFAP157

1.48e-0418963457ab947b81dbd9d3e896be89e28c4a62cf720837
ToppCell343B-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DZIP3 GPR162 OMG CFAP157

1.48e-04189634ebc16b8eab84167d74446783d7e802acedc6b9c6
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNA3 TECRL CACNA2D3 PDZRN4

1.48e-04189634e758b264c0a47127e33e66c395cf5a3224c7305b
ToppCellfacs-Skin-Anagen-3m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 CCDC18 PIF1 BORA

1.48e-04189634bfa3ed1360991a3e32fad133017c413f8adc1eba
ToppCellfacs-Skin-Anagen-3m-Epithelial-keratinocyte_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KNTC1 CCDC18 PIF1 BORA

1.48e-0418963496f10c63656e446b4bb712f012e91ae986f8c2d0
ToppCellfacs-Heart-RA-24m-Mesenchymal-ventricular_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CTNNA3 TECRL CACNA2D3 PDZRN4

1.48e-04189634b98f60875b1a12b2ec9dc91889298ae57f98602f
ToppCellCOVID-19-Heart|COVID-19 / Disease (COVID-19 only), tissue and cell type

KALRN CTNNA3 TECRL DMD

1.51e-04190634918ad5037881212008f9f69d5df5da91fd01422c
ToppCellEpithelial_cells-Ciliated_cells-B|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

DZIP3 GPR162 OMG CFAP157

1.51e-04190634426a4806f6e39d4d57c6746609d30bb3ca62df7d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 CTNNA3 DMD PDZRN4

1.51e-041906345681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellLV-06._Ventricular_Cardiomyocyte_II|LV / Chamber and Cluster_Paper

DST CTNNA3 TECRL DMD

1.54e-0419163425f3eb34f4e70761e81e84c8a5829f216108cbc6
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DZIP3 GPR162 OMG CFAP157

1.54e-04191634dad675251e129254955eac179c84a641a4864586
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

DMXL2 DST SMC6 ABCD2

1.54e-041916347bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCell356C-Epithelial_cells-Epithelial-F_(Ciliated)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

DZIP3 GPR162 OMG CFAP157

1.54e-041916346d2cf41ee946137c039ddcc13593fc3f670afbba
ToppCellfacs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DST SV2A CD79A PRKG2

1.54e-041916343387b95a3f2445c672d407922fdce3a91eabaef8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN CTNNA3 DMD PDZRN4

1.57e-04192634bfab13793e54de2550ee171397f7ece0625cdb4a
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

KALRN CTNNA3 DMD PDZRN4

1.57e-04192634b54b0d5b88139905521c8d5d58332e89c08d589c
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DZIP3 GPR162 OMG CFAP157

1.57e-0419263403acd4a26b986e34eee608747347791122f1aa52
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-ciliated_cell-Epi-Ciliated|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

DZIP3 GPR162 OMG CFAP157

1.57e-0419263431c6046589e2fbb0486fd044c5b128099d37872f
ToppCell15-Trachea-Epithelial-Multiciliated_cell|Trachea / Age, Tissue, Lineage and Cell class

DZIP3 GPR162 OMG CFAP157

1.60e-04193634aa3acc7571405169efb656d214f3a8cbf988362e
ToppCellhuman_hepatoblastoma-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

KNTC1 CCDC18 PIF1 BORA

1.60e-041936344b9fa2a4424f8abe63fa7bee78db93dda04ab15f
ToppCellCOVID-19-Fibroblasts-Other_FB|COVID-19 / group, cell type (main and fine annotations)

TGFBR3 SGIP1 DST DMD

1.60e-04193634e6b75be08e33c1de079fb5c02f0b4468128b369c
ToppCellRA-03._Atrial_Cardiomyocyte|World / Chamber and Cluster_Paper

RHBDL3 CTNNA3 TECRL DMD

1.64e-0419463489812fb164065041357bb37a3c2d87028ec3de4e
ToppCellCTRL-Myeloid-Alveolar_Macrophage|CTRL / Disease state, Lineage and Cell class

DMXL2 DST GLIPR2 DENND4C

1.64e-04194634be69b20afa915978c4cf2feb0bb21ab7c1f301a5
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 KALRN DMD PDZRN4

1.64e-04194634ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellnormal_Lung-Epithelial_cells-Ciliated|Epithelial_cells / Location, Cell class and cell subclass

DZIP3 GPR162 OMG CFAP157

1.67e-04195634a3e2999fdd4c3575add6e28ecfd1d6606a61f992
ToppCellCOVID-19-Heart-CM_2|Heart / Disease (COVID-19 only), tissue and cell type

DST CTNNA3 TECRL DMD

1.67e-0419563475fc81bddb246dca3b437fb60827b1d4fe416405
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

SGIP1 DST KALRN TBL1XR1

1.67e-041956340e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 KALRN DMD PDZRN4

1.67e-04195634edd4cd8402af81737b2074f9dce71cc6ab09be7e
ToppCellcellseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

DZIP3 GPR162 OMG CFAP157

1.67e-04195634e7f069f557a59ee7b502ff82ad4c9f47fa619ba8
ToppCellCOVID-19-Epithelial-Ciliated_cells|Epithelial / Condition, Lineage and Cell class

DZIP3 GPR162 OMG CFAP157

1.70e-04196634de7aa31354b019d7321a8ef965d59ce2e8b89276
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 KALRN DMD PDZRN4

1.70e-04196634b8759e6231e0254797d6c30930407b79440c57bb
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KALRN CTNNA3 CACNA2D3 PDZRN4

1.70e-041966349830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SGIP1 KALRN DMD PDZRN4

1.74e-04197634bf0520a94ebb1d2f94de9f526d17e0b0e8fe7052
ToppCellcontrol-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DZIP3 GPR162 OMG CFAP157

1.74e-04197634e453d085182364ca347cbcc9dc995c62c3353016
ToppCellcontrol-Epithelial-Ciliated|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DZIP3 GPR162 OMG CFAP157

1.74e-04197634d4e963c1f82996371bf3d63578ee9fce8e00c5a8
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGIP1 KALRN DMD PDZRN4

1.77e-0419863479576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell5'-GW_trimst-1-SmallIntestine-Mesenchymal-immature_mesenchymal_cell-cycling_stromal|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CCDC18 DZIP3 PIF1 BORA

1.77e-04198634c3dd887c95587f930b7afd32385627a9fa029ca4
ToppCellFetal_29-31_weeks|World / Lineage, Cell type, age group and donor

SGIP1 KALRN CTNNA3 SMARCA1

1.80e-041996345b9d355795dd03a22f0961dfd143425c367a4654
ToppCellCTRL-Myeloid|CTRL / Disease state, Lineage and Cell class

DMXL2 DST TRIO GLIPR2

1.80e-0419963470b89a930709fdb91fde6f96106add8455b11618
ToppCellSepsis-Bac-SEP-Lymphocyte-T/NK-dn_T|Bac-SEP / Disease, condition lineage and cell class

NAPB DZIP3 ABCD2 BORA

1.80e-041996344150a479b80596accf679b37aa9b0ac15cc132b2
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

STARD13 TRIO DMD TBL1XR1

1.80e-0419963494b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellCOVID-19-kidney-Fibroblast-1|kidney / Disease (COVID-19 only), tissue and cell type

SGIP1 DST KALRN DMD

1.80e-041996349503646ff1ad248181146ce767e9d12e882ec3bd
ToppCellControl_saline-Endothelial-Endothelial-FOXM1|Control_saline / Treatment groups by lineage, cell group, cell type

KNTC1 CCDC18 PIF1 BORA

1.84e-042006349bbc7b5561151f6ff65f40b3226271def732e5d9
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TGFBR3 SGIP1 DST PDZRN4

1.84e-04200634389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBrain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Interneuron|3m / Sample Type, Dataset, Time_group, and Cell type.

DST KALRN RPS3A PDZRN4

1.84e-04200634a313b9a8bde1ea80a6eae183b76fba46b86558b4
ToppCellBiopsy_IPF-Epithelial-Ciliated|Biopsy_IPF / Sample group, Lineage and Cell type

DZIP3 GPR162 OMG CFAP157

1.84e-04200634bb8c99156e547a8eb6599b6b6bc3c66bf77af7f8
ToppCellLPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

TGFBR3 TCAF1 CTNNA3 DMD

1.84e-0420063409537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCellcontrol-cDC|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

DST TRIO EIF2AK4 CACNA2D3

1.84e-042006344a6d17a4225be38537d3dd8a39512051f597f4e0
ToppCellLPS_only-Mesenchymal_myocytic-Myofibroblastic|LPS_only / Treatment groups by lineage, cell group, cell type

TGFBR3 TCAF1 DST DMD

1.84e-0420063402cae2c296a13ad4cbb53bca7a86d64629d67d66
ToppCellLPS_IL1RA-Mesenchymal_myocytic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

TGFBR3 SGIP1 CTNNA3 DMD

1.84e-0420063477631c471cc5d453a749784f838cfa6408caf09b
Diseasesensory system disease (implicated_via_orthology)

TBL1Y TBL1XR1

1.22e-053602DOID:0050155 (implicated_via_orthology)
Diseaseneutropenia, response to metamizole, Drug-induced agranulocytosis

STARD13 TGFBR3

6.07e-056602EFO_0010971, HP_0012235, MONDO_0001475
Diseaseneuroblastoma

SGIP1 TRIO KALRN PDZRN4

9.33e-05116604EFO_0000621
Diseaseinosine measurement

CTNNA3 DMD

6.80e-0419602EFO_0010503
DiseaseNeurodevelopmental Disorders

TRIO TBL1XR1 CACNA2D3

9.11e-0493603C1535926
DiseaseAdenocarcinoma of large intestine

MAP3K15 PRKG2 TBL1XR1

9.98e-0496603C1319315
DiseaseLymphoma, Non-Hodgkin

CD79A TBL1XR1

1.94e-0332602C0024305

Protein segments in the cluster

PeptideGeneStartEntry
QMSMSRAINLTQKLW

EIF2AK4

1406

Q9P2K8
MTHMLNAAADRVKWT

ABCD2

1

Q9UBJ2
MSMDANGKIIWAKHS

COPB2

306

P35606
QHWAAMAQQVKMDLS

FBXW10

306

Q5XX13
QALWMHKVPASLMVS

CD79A

31

P11912
MMISKHIDGSLNQWA

DMXL2

611

Q8TDJ6
LHWQVKNVMKNIMAG

DMD

116

P11532
QQWLIKLTSKQMMTM

MT-ATP6

46

P00846
WHKEMLQQLLVMLSS

CFAP157

396

Q5JU67
ALNSMVEKHLNSQMW

ATXN7L1

491

Q9ULK2
NWMTIQELMTHGAKS

PDZRN4

1006

Q6ZMN7
QHWAAMAQQVKMDLS

FBXW10B

306

O95170
NSMKMWEYKHTEIQA

DGKK

1041

Q5KSL6
KKQALHAVMGIWMVS

GPR162

131

Q16538
ESSAMMQWLQKMNKT

DST

4521

Q03001
SLRQSEMKNAMKNLW

OR4A16

286

Q8NH70
AEKVALHWQQLMLKM

KALRN

981

O60229
MIKGLWKNHSHESMA

KNTC1

1946

P50748
SHWTKSGENQIMMTK

TMEM63A

491

O94886
QLSMKRSQWEMEKHN

DZIP3

826

Q86Y13
MSNWKLSKALSLEMI

PRKG2

421

Q13237
LSVLSTNMKHLLMWS

IL20RB

41

Q6UXL0
KTTALMMAWHKVTTN

LRRC70

426

Q7Z2Q7
KNTMEMYKRTWENHI

CTNNA3

476

Q9UI47
TGHFTAMVWKNTKKM

GLIPR2

101

Q9H4G4
MEMISHQENHAKWKI

CCDC18

1226

Q5T9S5
WHSDMTAKAQKLKQT

CACNA2D3

951

Q8IZS8
NMKQDHTTQRCWMKT

BORA

536

Q6PGQ7
MKQAATVASKMWVAV

DENND4C

1366

Q5VZ89
KGMTSSQWFKIQHMQ

RNASE7

31

Q9H1E1
VLMKQIHKTSQCMWL

IPO13

576

O94829
RDVKNMISTWMQSNH

KRBA2

366

Q6ZNG9
MKQMHEWNFTASSIK

MAP3K15

566

Q6ZN16
LQLAWAMSIHKSQGM

PIF1

546

Q9H611
AIMEKHSMSNKHGWT

STARD13

626

Q9Y3M8
HDVKMMTRDGQKWSQ

SUPT20HL1

176

Q3ZLR7
MVLVPKSTLHNWMNE

SMARCA1

236

P28370
SHQNRHAMMMKSWKI

BMT2

281

Q1RMZ1
MSTWIIMKNIVAKNG

SLC25A40

281

Q8TBP6
ENVDKMNLWVKMFSH

TCAF1

861

Q9Y4C2
SAHLANIVMNWSGMK

RHBDL3

286

P58872
CSMVKKWQTMIEAHV

RPS3A

111

P61247
QKFQSHMWSQMLVST

TAF2

486

Q6P1X5
HMWSQMLVSTSGFLK

TAF2

491

Q6P1X5
LNNSSEMKLVQMKWH

MED24

561

O75448
HKQNITYLLKWMMET

OMG

231

P23515
MTLKIWSMKQDNCVH

TBL1XR1

371

Q9BZK7
RHMQMQEKTFTKWIN

SPTBN5

51

Q9NRC6
WMVLKQVHDTNMRAK

SV2A

371

Q7L0J3
TFKQSTAWMLHMAVR

CHST4

81

Q8NCG5
MERMSLKHQNSGKWA

UTP14C

291

Q5TAP6
QAAKQMDSNWTLMKM

XPNPEP1

81

Q9NQW7
WVNMPNLMTHLKKVS

SGIP1

646

Q9BQI5
TMKTNLESLKHEMAW

SMC6

266

Q96SB8
TRAANMFKMAKNWSA

NAPB

46

Q9H115
MTLKIWSMKQDACVH

TBL1Y

381

Q9BQ87
ALTAMSKMQWQNVEH

VPS53

616

Q5VIR6
TMLKMVWISKASAIQ

YTHDC2

721

Q9H6S0
LWMMETETQRSSKHQ

ZNF227

81

Q86WZ6
KSLTLSQRALQWNMM

ZKSCAN7

246

Q9P0L1
TLLMSIQMSLWAQKK

TECRL

326

Q5HYJ1
KSFSWKASMKFHQRM

ZNF425

561

Q6IV72
NAVKMIKLTMHNWSS

ZNF891

136

A8MT65
SIIWAMMQNKKTFTK

TGFBR3

736

Q03167
KVASHWQQLMLKMED

TRIO

991

O75962
KTTLAMQAMLHWANG

NLRP13

241

Q86W25