Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaspartic-type endopeptidase activity

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9

2.96e-0737775GO:0004190
GeneOntologyMolecularFunctionaspartic-type peptidase activity

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9

3.40e-0738775GO:0070001
GeneOntologyMolecularFunctionzinc ion binding

ERVK-6 SEC24D RECQL4 WT1 HRG PAM PAPPA ERVK-19 TRIM21 ERVK-7 ERVK-21 ERVK-9 TAB3 CA6

6.84e-068917714GO:0008270
GeneOntologyMolecularFunctiontransition metal ion binding

ERVK-6 SEC24D RECQL4 WT1 HRG PAM PAPPA ERVK-19 TRIM21 ERVK-7 ERVK-21 ERVK-9 NOS3 TAB3 CA6

4.13e-0511897715GO:0046914
GeneOntologyMolecularFunctionheparan sulfate proteoglycan binding

LRP1 HRG SEMA5A

1.87e-0429773GO:0043395
GeneOntologyMolecularFunctionRNA-DNA hybrid ribonuclease activity

ERVK-6 ERVK-7

7.89e-0411772GO:0004523
DomainNotch_dom

PAPPA NOTCH2

3.21e-047742IPR000800
DomainNotch

PAPPA NOTCH2

3.21e-047742PF00066
DomainNL

PAPPA NOTCH2

3.21e-047742SM00004
DomainTIL

FCGBP MUC6

9.96e-0412742PF01826
DomainC8

FCGBP MUC6

9.96e-0412742PF08742
DomainSushi

PAPPA CSMD1 CSMD3

1.15e-0352743PF00084
DomainUnchr_dom_Cys-rich

FCGBP MUC6

1.17e-0313742IPR014853
DomainC8

FCGBP MUC6

1.17e-0313742SM00832
DomainCCP

PAPPA CSMD1 CSMD3

1.28e-0354743SM00032
DomainTIL_dom

FCGBP MUC6

1.37e-0314742IPR002919
DomainSUSHI

PAPPA CSMD1 CSMD3

1.42e-0356743PS50923
DomainSushi_SCR_CCP_dom

PAPPA CSMD1 CSMD3

1.50e-0357743IPR000436
DomainVWD

FCGBP MUC6

1.79e-0316742SM00216
DomainVWF_type-D

FCGBP MUC6

1.79e-0316742IPR001846
DomainVWFD

FCGBP MUC6

1.79e-0316742PS51233
DomainVWD

FCGBP MUC6

1.79e-0316742PF00094
DomainVWC_out

FCGBP MUC6

2.54e-0319742SM00215
DomainSOCS

ASB2 SOCS7

2.81e-0320742SM00253
DomainEGF-like_dom

FCGBP ADAM20 LRP1 LAMA2 NOTCH2

3.09e-03249745IPR000742
DomainWGR_domain

PARP6 LAMA2

4.04e-0324742IPR008893
DomainZF_RING_1

RNF224 RNF38 TRIM21 SH3RF3 RNF43

5.95e-03291745PS00518
Domain-

LAMA2 PAPPA LGALS4

6.37e-03957432.60.120.200
DomainZF_RING_2

RNF224 RNF38 TRIM21 SH3RF3 RNF43

6.57e-03298745PS50089
DomainSema

SEMA5A PLXNB3

6.69e-0331742SM00630
DomainSemap_dom

SEMA5A PLXNB3

6.69e-0331742IPR001627
DomainSema

SEMA5A PLXNB3

6.69e-0331742PF01403
DomainSEMA

SEMA5A PLXNB3

6.69e-0331742PS51004
DomainPSI

SEMA5A PLXNB3

7.11e-0332742PF01437
DomainPlexin_repeat

SEMA5A PLXNB3

7.11e-0332742IPR002165
DomainRING

RNF224 RNF38 TRIM21 SH3RF3 RNF43

7.23e-03305745SM00184
Pubmed

Quantitation of HERV-K env gene expression and splicing in human breast cancer.

ERVK-6 ERVK-19 ERVK-7 ERVK-21

1.36e-10581412629516
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

NCOA6 PDCD6IP SCN10A WT1 RNF38 CHD7 ATG2A TSC22D2 BCAR1 EIF4G3 WNK1 SOS2

3.59e-10430811235044719
Pubmed

Genomewide screening for fusogenic human endogenous retrovirus envelopes identifies syncytin 2, a gene conserved on primate evolution.

ERVK-6 ERVK-19 ERVK-21 ERVK-9

1.33e-081281414557543
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

NCOA6 PDCD6IP ATXN1 IQSEC2 CCDC85C BCAR1 EIF4G3 CDC25B WNK1 ERBIN SH3RF3 NOTCH2 TAB3

9.54e-08861811336931259
Pubmed

Human endogenous retrovirus HERV-K(HML-2) proviruses with Rec protein coding capacity and transcriptional activity.

ERVK-6 ERVK-19 ERVK-9

2.42e-07681315063128
Pubmed

Survey of human genes of retroviral origin: identification and transcriptome of the genes with coding capacity for complete envelope proteins.

ERVK-6 ERVK-19 ERVK-21

1.44e-061081312970426
Pubmed

A revised nomenclature for transcribed human endogenous retroviral loci.

ERVK-6 ERVK-19 ERVK-7 ERVK-21 ERVK-9

2.82e-069481521542922
Pubmed

Identification of semaphorin 5A interacting protein by applying apriori knowledge and peptide complementarity related to protein evolution and structure.

SEMA5A PLXNB3

5.36e-06281219329067
Pubmed

Expression of human endogenous retrovirus type K envelope glycoprotein in insect and mammalian cells.

ERVK-6 ERVK-19

5.36e-0628129060628
Pubmed

Evolutionary relationships within a subgroup of HERV-K-related human endogenous retroviruses.

ERVK-6 ERVK-19

5.36e-0628129460924
Pubmed

SEMA5A-PLXNB3 Axis Promotes PDAC Liver Metastasis Outgrowth through Enhancing the Warburg Effect.

SEMA5A PLXNB3

5.36e-06281236741230
Pubmed

Great vessel development requires biallelic expression of Chd7 and Tbx1 in pharyngeal ectoderm in mice.

FOXN1 ETV4 CHD7

5.43e-061581319855134
Pubmed

Functional proteomics mapping of a human signaling pathway.

NCOA6 SEC24D PDCD6IP LRP1 PAPPA ASB2 ERBIN BAG6 NOTCH2

9.78e-0659181915231748
Pubmed

Identification of two new members of the CSMD gene family.

CSMD1 CSMD3

1.60e-05381212906867
Pubmed

Identification of an active reverse transcriptase enzyme encoded by a human endogenous HERV-K retrovirus.

ERVK-6 ERVK-9

1.60e-0538129971820
Pubmed

Urokinase-type plasminogen activator (uPA) induces pulmonary microvascular endothelial permeability through low density lipoprotein receptor-related protein (LRP)-dependent activation of endothelial nitric-oxide synthase.

LRP1 NOS3

1.60e-05381221540184
Pubmed

Human Pluripotent Stem Cell-Derived Multipotent Vascular Progenitors of the Mesothelium Lineage Have Utility in Tissue Engineering and Repair.

FOXN1 WT1

1.60e-05381230840882
Pubmed

Association Between eNOS, MMP-9, BAG-6 Gene Polymorphisms and Risk of Hypertensive Disorders of Pregnancy in the Northern Chinese Population.

BAG6 NOS3

1.60e-05381233539267
Pubmed

Genome-wide screening, cloning, chromosomal assignment, and expression of full-length human endogenous retrovirus type K.

ERVK-6 ERVK-19

1.60e-05381210516026
Pubmed

Hepatocyte nuclear factor 1β controls nephron tubular development.

HNF1A WT1 NOTCH2

2.08e-052381323362349
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

UBE2O LRP1 LAMA2 MUC6

2.36e-057181433541421
Pubmed

Semaphorin 5A and plexin-B3 inhibit human glioma cell motility through RhoGDIalpha-mediated inactivation of Rac1 GTPase.

SEMA5A PLXNB3

3.20e-05481220696765
Pubmed

Semaphorin 5A promotes angiogenesis by increasing endothelial cell proliferation, migration, and decreasing apoptosis.

SEMA5A PLXNB3

3.20e-05481219850054
Pubmed

Semaphorin 5A and plexin-B3 regulate human glioma cell motility and morphology through Rac1 and the actin cytoskeleton.

SEMA5A PLXNB3

3.20e-05481221706053
Pubmed

Many human endogenous retrovirus K (HERV-K) proviruses are unique to humans.

ERVK-6 ERVK-7

3.20e-05481210469592
Pubmed

LRP1 induces anti-PD-1 resistance by modulating the DLL4-NOTCH2-CCL2 axis and redirecting M2-like macrophage polarisation in bladder cancer.

LRP1 NOTCH2

3.20e-05481238462037
Pubmed

Human endogenous retrovirus K10: expression of Gag protein and detection of antibodies in patients with seminomas.

ERVK-6 ERVK-19

3.20e-0548127983737
Pubmed

Transcriptionally active HERV-K genes: identification, isolation, and chromosomal mapping.

ERVK-6 ERVK-7

5.33e-05581211401426
Pubmed

Plexin-B3 is a functional receptor for semaphorin 5A.

SEMA5A PLXNB3

5.33e-05581215218527
Pubmed

Notch signaling regulates smooth muscle differentiation of epicardium-derived cells.

WT1 NOS3 NOTCH2

7.55e-053581321252157
Pubmed

Rab11-FIP1 and Rab11-FIP5 Regulate pIgR/pIgA Transcytosis through TRIM21-Mediated Polyubiquitination.

LAMA2 TRIM21 NOTCH2

1.22e-044181334638806
Pubmed

A human MAP kinase interactome.

PDCD6IP ATXN1 TRIM21 WNK1 ERBIN PYGO1 SOS2

1.42e-0448681720936779
Pubmed

Hepatocyte nuclear factor 4 alpha is related to survival of the condensed mesenchyme in the developing mouse kidney.

HNF1A WT1

1.49e-04881220235219
Pubmed

Nitric oxide synthase-3 deficiency results in hypoplastic coronary arteries and postnatal myocardial infarction.

WT1 NOS3

1.49e-04881223048191
Pubmed

The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.

WT1 NOTCH2

1.49e-04881219914235
Pubmed

Wt1 and retinoic acid signaling are essential for stellate cell development and liver morphogenesis.

HNF1A WT1

1.49e-04881218028902
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

PDCD6IP ATXN1 LRP1 CCDC85C BCAR1 CSMD1 PLD3 EIF4G3 ERBIN SH3RF3 NOTCH2 SOS2

1.67e-041489811228611215
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

NCOA6 CHD7 WNK1 ERBIN DIS3

1.86e-0422581512168954
Pubmed

HIV-1 protein Tat produces biphasic changes in NMDA-evoked increases in intracellular Ca2+ concentration via activation of Src kinase and nitric oxide signaling pathways.

LRP1 NOS3

1.91e-04981224666322
Pubmed

Overexpression of RNF38 facilitates TGF-β signaling by Ubiquitinating and degrading AHNAK in hepatocellular carcinoma.

RNF38 TRIM21

1.91e-04981230836988
Pubmed

Regulation of the CUL3 Ubiquitin Ligase by a Calcium-Dependent Co-adaptor.

SEC24D PDCD6IP BAG6

2.20e-045081327716508
Pubmed

Twenty proteins containing a C-terminal SOCS box form five structural classes.

ASB2 SOCS7

2.38e-04108129419338
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

EAF1 ATXN1 ARRDC4 LRP1 CSMD1 RNF43 NOTCH2 TCTN2 BAHCC1 ALG13

2.65e-041116811031753913
Pubmed

The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.

WT1 HRG TTI1 TRIM21 CHD7 BAG6

3.32e-0439681626687479
Pubmed

The reaper-binding protein scythe modulates apoptosis and proliferation during mammalian development.

WT1 BAG6

3.48e-041281216287848
Pubmed

Urogenital development in Pallister-Hall syndrome is disrupted in a cell-lineage-specific manner by constitutive expression of GLI3 repressor.

WT1 ETV4

3.48e-041281226604140
Pubmed

Notch signaling promotes nephrogenesis by downregulating Six2.

WT1 NOTCH2

3.48e-041281227633993
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

UBE2O CCDC85C ERBIN RNF43 TAB3

3.82e-0426381534702444
Pubmed

Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation.

WT1 NOTCH2

4.11e-041381211171333
Pubmed

hnRNPU is required for spermatogonial stem cell pool establishment in mice.

WT1 ETV4

4.11e-041381238625792
Pubmed

Etv4 regulates nociception by controlling peptidergic sensory neuron development and peripheral tissue innervation.

SCN10A ETV4

4.11e-041381235904071
Pubmed

Phosphoproteome analysis of HeLa cells using stable isotope labeling with amino acids in cell culture (SILAC).

LAMA2 BCAR1

4.11e-041381216212419
Pubmed

Ubiquitin-Activated Interaction Traps (UBAITs) identify E3 ligase binding partners.

PDCD6IP BAG6 DIS3

4.17e-046281326508657
Pubmed

Revisiting the role of Notch in nephron segmentation confirms a role for proximal fate selection during mouse and human nephrogenesis.

WT1 NOTCH2

4.79e-041481235451473
Pubmed

Bmp in podocytes is essential for normal glomerular capillary formation.

WT1 NOTCH2

4.79e-041481218272846
Pubmed

The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development.

WT1 NOTCH2

4.79e-041481223806616
Pubmed

A high-throughput approach for measuring temporal changes in the interactome.

PARP6 SEC24D UBE2O PDCD6IP TTI1 INTS9 BCAR1 PLD3 WNK1 BAG6 DIS3

5.46e-041455811122863883
Pubmed

Ripply3, a Tbx1 repressor, is required for development of the pharyngeal apparatus and its derivatives in mice.

FOXN1 ETV4

5.52e-041581221177346
Pubmed

Lack of replication of association findings in complex disease: an analysis of 15 polymorphisms in prior candidate genes for sporadic Alzheimer's disease.

LRP1 NOS3

5.52e-041581211436125
Pubmed

Non-muscle myosin II deletion in the developing kidney causes ureter-bladder misconnection and apical extrusion of the nephric duct lineage epithelia.

WT1 ETV4

5.52e-041581228478097
Pubmed

Mapping lineage progression of somatic progenitor cells in the mouse fetal testis.

WT1 NOTCH2

5.52e-041581227621062
Pubmed

Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.

WT1 LAMA2

5.52e-041581210625553
Pubmed

Localised inhibition of FGF signalling in the third pharyngeal pouch is required for normal thymus and parathyroid organogenesis.

FOXN1 ETV4

6.29e-041681222912418
Pubmed

Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.

WT1 NOTCH2

6.29e-041681217229764
Pubmed

The Lineage Differentiation and Dynamic Heterogeneity of Thymic Epithelial Cells During Thymus Organogenesis.

FOXN1 HNF1A

6.29e-041681235273595
Pubmed

Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.

WT1 NOTCH2

6.29e-041681224353058
Pubmed

A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.

SEC24D EAF1 IQSEC2 CCDC85C LSM11 ATG2A CDC25B WNK1 ERBIN

6.92e-04103881926673895
Pubmed

A critical role for the chromatin remodeller CHD7 in anterior mesoderm during cardiovascular development.

WT1 CHD7

7.12e-041781226102480
Pubmed

A perivascular niche for multipotent progenitors in the fetal testis.

WT1 NOTCH2

7.12e-041781230375389
Pubmed

FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling.

WT1 ETV4

8.00e-041881230853441
Pubmed

Deletion of the prorenin receptor from the ureteric bud causes renal hypodysplasia.

WT1 ETV4

8.00e-041881223704941
Pubmed

Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.

WT1 NOTCH2

8.00e-041881229113990
Pubmed

A direct functional link between the multi-PDZ domain protein GRIP1 and the Fraser syndrome protein Fras1.

WT1 LAMA2

8.00e-041881214730302
Pubmed

Pygo1 and Pygo2 roles in Wnt signaling in mammalian kidney development.

WT1 PYGO1

8.00e-041881217425782
Pubmed

Expression patterns of transcribed human endogenous retrovirus HERV-K(HML-2) loci in human tissues and the need for a HERV Transcriptome Project.

ERVK-21 ERVK-9

8.00e-041881218664271
Pubmed

Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.

ATXN1 ETV4 TRIM21 AURKAIP1 CSMD1 PLD3 ERBIN SLC38A3 CA6 ALG13

8.34e-041293811015342556
Pubmed

Human chromosome 11 DNA sequence and analysis including novel gene identification.

WT1 NDUFV1-DT MUC6

8.79e-048081316554811
Pubmed

Loss of Ataxin-1 Potentiates Alzheimer's Pathogenesis by Elevating Cerebral BACE1 Transcription.

ATXN1 ETV4

8.93e-041981231442405
Pubmed

Loss of Wiz Function Affects Methylation Pattern in Palate Development and Leads to Cleft Palate.

ETV4 NOTCH2

8.93e-041981234150743
Pubmed

Deletion of the epidermis derived laminin γ1 chain leads to defects in the regulation of late hair morphogenesis.

FOXN1 LAMA2

8.93e-041981227234308
Pubmed

ATXN1 protein family and CIC regulate extracellular matrix remodeling and lung alveolarization.

ATXN1 ETV4

8.93e-041981222014525
Pubmed

Utility of genetic and non-genetic risk factors in prediction of type 2 diabetes: Whitehall II prospective cohort study.

HNF1A NOTCH2

9.91e-042081220075150
Pubmed

Prorenin receptor is critical for nephron progenitors.

WT1 ETV4

9.91e-042081226658320
Pubmed

Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.

FCGBP CSMD1 WNK1

1.01e-038481315203218
Pubmed

ARRDC1 and ARRDC3 act as tumor suppressors in renal cell carcinoma by facilitating YAP1 degradation.

UBE2O PLD3

1.09e-032181229416926
Pubmed

Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.

HNF1A WT1

1.09e-032181227591083
Pubmed

Endothelial PlexinD1 signaling instructs spinal cord vascularization and motor neuron development.

PAPPA SEMA5A

1.20e-032281236549270
Pubmed

Epicardial function of canonical Wnt-, Hedgehog-, Fgfr1/2-, and Pdgfra-signalling.

WT1 ETV4

1.20e-032281224000064
Pubmed

Polygenic risk variants for type 2 diabetes susceptibility modify age at diagnosis in monogenic HNF1A diabetes.

HNF1A NOTCH2

1.20e-032281219794065
Pubmed

Putative complement control protein CSMD3 dysfunction impairs synaptogenesis and induces neurodevelopmental disorders.

LAMA2 CSMD3

1.20e-032281235245678
Pubmed

Cytosolic quality control of mislocalized proteins requires RNF126 recruitment to Bag6.

TRIM21 BAG6

1.20e-032281224981174
Pubmed

Sertoli Cell Wt1 Regulates Peritubular Myoid Cell and Fetal Leydig Cell Differentiation during Fetal Testis Development.

WT1 NOTCH2

1.31e-032381228036337
Pubmed

Targeted disruption of the histone lysine 79 methyltransferase Dot1L in nephron progenitors causes congenital renal dysplasia.

WT1 NOTCH2

1.31e-032381233315499
Pubmed

PTPRA Phosphatase Regulates GDNF-Dependent RET Signaling and Inhibits the RET Mutant MEN2A Oncogenic Potential.

ERBIN NOTCH2 SOS2

1.40e-039481332062451
Pubmed

Loss of Gata5 in mice leads to bicuspid aortic valve.

NOS3 NOTCH2

1.43e-032481221633169
Pubmed

Genome-wide association study of periodontal health measured by probing depth in adults ages 18-49 years.

LAMA2 SOS2

1.43e-032481224347629
Pubmed

A semaphorin code defines subpopulations of spinal motor neurons during mouse development.

ETV4 SEMA5A

1.43e-032481215869472
Pubmed

Myocardium defects and ventricular hypoplasia in mice homozygous null for the Forkhead Box M1 transcription factor.

LAMA2 CDC25B

1.43e-032481217366632
Pubmed

Transcriptional control of motor pool formation and motor circuit connectivity by the LIM-HD protein Isl2.

ETV4 SEMA5A

1.55e-032581237869988
Pubmed

Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans.

ATXN1 ETV4

1.55e-032581228288114
InteractionERVK-21 interactions

TRIM21 ERVK-21

1.44e-052772int:ERVK-21
InteractionYWHAG interactions

NCOA6 HNF1A PDCD6IP ATXN1 IQSEC2 RECQL4 CCDC85C TRIM21 BCAR1 EIF4G3 CDC25B WNK1 ERBIN SH3RF3 NOTCH2 TAB3

1.60e-0512487716int:YWHAG
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAPPA CSMD1 CSMD3

6.22e-04575331179
GeneFamilyRing finger proteins

RNF224 RNF38 TRIM21 SH3RF3 RNF43

1.24e-0327553558
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O ASB2 CDC25B RNF43 PLXNB3

6.67e-061567555caefdc6cc86f2ac52abe8c8da821db14f476915
ToppCellfacs-Marrow-T_cells-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O ASB2 CDC25B RNF43 PLXNB3

6.67e-06156755758f57dc10fc5cad200bf5b310c10ec9b1405f23
ToppCelldroplet-Liver-Npc-18m-Lymphocytic-macrophage/monocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O TTI1 ASB2 NOTCH2 BAHCC1

1.26e-0517875509d2687e0d79f12e90af35fc1c0453d249cf2d19
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CCDC85C CHD7 RNF43 PLXNB3 SOCS7

1.60e-05187755f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCellfacs-Thymus-Thymus_Epithelium|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM SEMA5A CSMD1

2.01e-051967556bc1187dfc4860a4e09032d7ea87ba3d9fe9f363
ToppCellfacs-Thymus-Thymus_Epithelium-18m|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM SEMA5A CSMD1

2.01e-05196755c8c89e469402e11aa2a9561e859b6fd1fb66c39b
ToppCellfacs-Trachea-3m|Trachea / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

SEC24D PAM TSC22D2 ERBIN NOTCH2

2.06e-05197755e77016d64b1cac9825fec7cfe5071f1567401187
ToppCellCaecum-B_cell-B_cell_IgG_Plasma|B_cell / Region, Cell class and subclass

HNF1A TTI1 MUC6 NOS3 PYGO1

2.06e-0519775540c8ff067e8242e2ca083ea04cd6026168191a97
ToppCellfacs-Trachea-nan-3m|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D PAM TSC22D2 ERBIN NOTCH2

2.06e-051977550353d925ee4b7aefc2c51b5fab873f465cdf9ebc
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 SEMA5A CSMD1 CSMD3 PLXNB3

2.16e-05199755333056c2abe9724efeab542c0365fcfe4eff8f18
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 SEMA5A CSMD1 CSMD3 PLXNB3

2.16e-05199755e60ecbb8fa7bcd3e2ce7d78f6efb2cfd1fd77698
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRP1 SEMA5A CSMD1 CSMD3 PLXNB3

2.21e-05200755ad777683adeb2ce45ade570386235e311fa7ea2d
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-Stem_cells|GW12 / Sample Type, Dataset, Time_group, and Cell type.

RECQL4 TTI1 CHD7 ERBIN NOTCH2

2.21e-052007554a57d6ba1531ce4e263daccd5de487977e6a1fdd
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW12-Stem_cells-Stem_cells|GW12 / Sample Type, Dataset, Time_group, and Cell type.

RECQL4 TTI1 CHD7 ERBIN NOTCH2

2.21e-05200755b706526b9c3485889a31253a1ffd017ad3f3fddc
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Mucinous_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

FCGBP CCDC185 WT1 MUC6

6.70e-05129754b0c3cbab552e1d540e6b03a691dd245f81715e0b
ToppCellfrontal_cortex-Non-neuronal-oligodendrocyte-Oligo-OPC_Pdgfra_Grm5|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CHD7 RNF43 SLC38A3 PLXNB3

7.54e-0513375463d2f096ae47d9b587acc6c5fbd346e5e58842b8
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RNF224 ARRDC4 RECQL4 CDC25B

9.45e-05141754f3b1d757c4cac8596c542959c8f27f8bcaf3f513
ToppCell367C-Epithelial_cells-Epithelial-D_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

RNF224 ARRDC4 RECQL4 CDC25B

9.45e-05141754bf68a54e755cda89fbc416636e522cd71d1e42d0
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf-Oligodendrocyte.Tfr.Ctps_(Ctps)|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FCGBP CCDC185 MUC6

1.10e-04557530b62b4f438a493a30bddb99e1eadd20c92704ee9
ToppCellSubstantia_nigra-Macroglia-POLYDENDROCYTE-P1-P1_1-Trf|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

FCGBP CCDC185 MUC6

1.10e-0455753fa556ea954ea868a4b23e410f3b27d69e04794ee
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 SEMA5A PRR22 LGALS4

1.14e-041487541d9fa6b2ee9feaed39c63d44e638b5c0942d947c
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

LAMA2 SEMA5A PRR22 LGALS4

1.20e-0415075498fdc6bdfde84d680e11d8727502b79afbf64303
ToppCellfacs-Marrow-T_cells-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 MS4A8 ASB2 PLXNB3

1.65e-0416375430cd95d4f37bd54c1fde54960cb005db58bdd30c
ToppCellfacs-Marrow-T_cells-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 MS4A8 ASB2 PLXNB3

1.65e-04163754ab934cb986495adfc8dbe5a276577f2a8fb6ee03
ToppCell5'-Adult-Appendix-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP WT1 DNAH6 RNF43

1.69e-0416475429da0175bd3808a5b3039a6161c764105608ef96
ToppCell5'-Adult-Appendix-Epithelial-goblet|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FCGBP WT1 DNAH6 RNF43

1.69e-04164754e83b632ac7e1dace946991ddfe1fbfbbffc3a88b
ToppCelldroplet-Marrow-BM-30m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

UBE2O ASB2 SH3RF3 PYGO1

1.69e-04164754758e85e2f5e7236b345e16c78344d5e0bf17d8dc
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD8-Tem/emra_CD8|GI_large-bowel / Manually curated celltypes from each tissue

MS4A8 RNF43 LGALS4 BAHCC1

1.77e-0416675413bef304ea3df8e8d2bc376a3287c78220a1b0c6
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WT1 ETV4 HRG PLXNB3

1.81e-04167754743df5908c1ceb43b34b240d9f9649f30f4142fa
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-mesothelial_cell-mesothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

WT1 ETV4 HRG PLXNB3

1.81e-041677541adb566f98af0109c8cc6e36033b89651e2c75e7
ToppCelldroplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP ETV4 SEMA5A CSMD1

1.90e-0416975430141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCelldroplet-Marrow-nan-18m-Lymphocytic-plasma_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQSEC2 LRP1 PLD3 TCTN2

1.94e-04170754067657ca7fcf5a0ffbd168b5c4609a30ca508f22
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CELF3 PAPPA CSMD1 NOTCH2

1.98e-041717544ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PAPPA SEMA5A CSMD3 PYGO1

2.12e-04174754f90ca117b729436cf452e2ddcec26ba525c5c13b
ToppCellFetal_29-31_weeks-Mesenchymal-vascular_smooth_muscle_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAM181A PAPPA SEMA5A CSMD1

2.12e-04174754015d3742d3d79a57413a333f00ef2d380a9848dd
ToppCellfacs-Pancreas-Exocrine-24m-Epithelial|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CSMD3 SLC38A3 LGALS4

2.17e-041757547329ebb135fc4311ee9595729b62a5d152c9de8c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ETV4 SEMA5A CSMD1

2.17e-04175754d67c77eee979ad029e7545f383326f0ff77c6e5f
ToppCellfacs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHD7 TSC22D2 WNK1 NOTCH2

2.17e-041757541ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ETV4 SEMA5A CSMD1

2.17e-041757541d1cdbf3221b03e24eae38afd57cbd6736b37a53
ToppCell3'-Child09-12-SmallIntestine-Epithelial-neuro-epithelial|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOXN1 CELF3 ETV4 SLC38A3

2.21e-041767542e1003dc373b14d27f0464d980453fdcfc1005f0
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CELF3 SEMA5A MAFIP PYGO1

2.26e-04177754f7a2e6b5e82f0565f8030696944f33c544233b94
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-BM_CD8_+_CD4_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN1 ASB2 PLD3 RNF43

2.26e-041777546d86b2f97426b552dff5ce6ddf0ead1285ed618e
ToppCell10x_5'_v1-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-Z|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CELF3 SEMA5A MAFIP PYGO1

2.26e-04177754ef02ee75db36a92dda889efb6fad1193efbc4be4
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-mature_alpha-beta_T_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATXN1 ASB2 PLD3 RNF43

2.26e-04177754d8b1bbc224d062a57a6ad40b4b2af5d6e0fe63b3
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma|TCGA-Colorectal / Sample_Type by Project: Shred V9

SHROOM4 NCOA6 ETV4 TTI1

2.41e-04180754c3d1521ac90f2e3fc31158e6e61907e05c37af39
ToppCellfacs-Pancreas-Exocrine-24m|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FCGBP CSMD3 SLC38A3 LGALS4

2.41e-0418075472310baeed848f2c483ae986cd73d2fb2cca7feb
ToppCell5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LRP1 LAMA2 PAM PAPPA

2.52e-041827543dfa9187e9d2bab1d199079d29209c4648220ada
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAPPA CSMD1 PLXNB3 ALG13

2.52e-041827546fdaf3c8c3952a8f14dd7288e523ed58eb1d3517
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 SEMA5A CHD7 NOTCH2

2.52e-041827543cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 SEMA5A CHD7 NOTCH2

2.52e-041827545d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LAMA2 PAPPA SEMA5A

2.57e-04183754ebe369dc80c4fbf8f4dbe947147f8c47507ffb60
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ETV4 SEMA5A CSMD1

2.62e-04184754278a7ed764c326450cb70e69ed2175980eaf5fe0
ToppCellfacs-Brain_Non-Myeloid-Cortex_-18m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ETV4 SEMA5A CSMD1

2.62e-041847548d86e125257ff1d3af8d90577a8b3f0321eca21c
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM181A CSMD1 CSMD3 PLXNB3

2.73e-04186754d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

SCN10A LRP1 CSMD1 CSMD3

2.73e-0418675423b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 MS4A8 PLD3 CA6

2.73e-041867547950e03ea080238c168b9d807e217f459acdfb28
ToppCellCV-Severe-3|Severe / Virus stimulation, Condition and Cluster

RECQL4 LRP1 PRR22 TSC22D2

2.79e-0418775468cb43a73945f5e252530da25613f6b3f484b4d5
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM4 RNF38 INTS9 NOTCH2

2.85e-041887546468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM4 RNF38 INTS9 NOTCH2

2.85e-041887547a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM4 RNF38 INTS9 NOTCH2

2.85e-041887549cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellControl-Fibroblasts-Adventitial_FB|Control / group, cell type (main and fine annotations)

LRP1 LAMA2 PAPPA SH3RF3

2.85e-04188754706a26c372add839d947749f0521a0e1f5c9b0ec
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ETV4 SEMA5A CSMD1

2.85e-04188754a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 ETV4 SEMA5A CSMD1

2.85e-04188754c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA2 SEMA5A ASB2 RNF43

2.90e-04189754f75cebd4c3e54e297557449ba67ccc8d1a2a14f5
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 CHD7 NOTCH2 PLXNB3

2.96e-041907542de8e4cfeee350a9a76af749d6ce58d948c129b8
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM181A CSMD1 CSMD3 PLXNB3

2.96e-04190754ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

WT1 LAMA2 PAPPA SEMA5A

2.96e-041907540fea33f2dc1efa23aaa2da1c318482a52a313ff1
ToppCelldroplet-Heart-nan-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM ASB2

2.96e-0419075496a92212ea3fb35fa3d0da495e504edc61c71c23
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM181A CSMD1 CSMD3 PLXNB3

2.96e-041907544971857eac9af17d66d673ed2ab7072639f60a10
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAPPA

3.02e-041917546cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAPPA

3.02e-04191754850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibroblast|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D WT1 LRP1 SEMA5A

3.02e-041917549214655dca96d766737c9f30b624d7fe7050342e
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAPPA

3.02e-041917548b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATXN1 WT1 LRP1 SH3RF3

3.02e-041917541caf726bd07fdca389e678fc16304a6ef1790423
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 LAMA2 PAM PAPPA

3.02e-041917549f478f36a0b895e607e3bb77fa0f9f03cc0f33fc
ToppCellAnterior_Cingulate_gyrus_(CgG)-Non-neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SHROOM4 CHD7 NOTCH2 PLXNB3

3.02e-04191754f3158cedf67e3b90aa94ea1f61c72c33aaa2d5ba
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ATXN1 WT1 LRP1 SH3RF3

3.02e-041917543d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellfacs-Aorta-Heart-18m-Mesenchymal|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM NOTCH2

3.08e-041927546d4fe7ea278efa4b9d43f8a3c282bc0e0e9abaea
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SEC24D LAMA2 PAPPA SEMA5A

3.08e-041927548d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM NOTCH2

3.08e-041927542c6406bc97c3224099b94a43f2890f057b528fa6
ToppCell3'-GW_trimst-1.5-SmallIntestine-Epithelial-mature_enterocytic-Colonocyte|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HNF1A FCGBP ETV4 LGALS4

3.08e-041927541a3d95a9801cc4569b67fa652b2af46c4dedbaef
ToppCellfacs-Aorta-Heart-18m-Mesenchymal-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM NOTCH2

3.08e-0419275447aed7c8e6f5ce1084821212a04f568319e65fd6
ToppCelldroplet-Fat-Mat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAPPA

3.14e-04193754ebd090d7801480b3cee45caac3d30cc991836769
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAPPA

3.14e-0419375422c58032e58730715224d7934968ce92d150b0e8
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

WT1 PAPPA SEMA5A CSMD3

3.14e-0419375468089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCellfacs-Diaphragm-Limb_Muscle-3m-Mesenchymal-mesenchymal_stem_cell|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAM

3.14e-04193754160691b671710be10220803d788c2c961c236af1
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

LAMA2 ETV4 SEMA5A RNF43

3.14e-04193754e2b455387d1de7812305200a2041a0f4759a6f54
ToppCelldroplet-Fat-Mat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAPPA

3.14e-04193754573ad2f848bede1fe20c7b4b352a9242ec294725
ToppCellControl-Fibroblasts-Intermediate_pathological_FB|Control / group, cell type (main and fine annotations)

WT1 LAMA2 PAPPA SH3RF3

3.21e-0419475403a269f75a481ea54aea8e6444605db8d6df493d
ToppCellfacs-MAT-Fat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAM

3.21e-04194754f906b090f67df4cfe3498cdbb52cc0efa08e06cc
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c03-GZMK|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

FCGBP ATXN1 ATG2A WNK1

3.21e-04194754b0a7f5ca0c6f4f5764a8b35b5de80d82b828c66c
ToppCellfacs-MAT-Fat-18m-Mesenchymal|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAM

3.21e-04194754944cdb0403d80a10a2eea2a3516a9343dbccc32c
ToppCellCOVID-19-Heart-Fib_2|Heart / Disease (COVID-19 only), tissue and cell type

LRP1 LAMA2 PAPPA NOTCH2

3.21e-04194754d91c9f2ec47319051fc398320693fddbe8bbd4d6
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

LAMA2 ETV4 SEMA5A RNF43

3.21e-04194754fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCellfacs-Heart-RA-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM NOTCH2

3.21e-04194754bc945450b350f597c3ff910d3a14a533d90086a8
ToppCellfacs-MAT-Fat-18m-Mesenchymal-mesenchymal_progenitor|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WT1 LRP1 LAMA2 PAM

3.21e-0419475485081d255fcc1e9854c0073321dd9f0feaa48866
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 LAMA2 SEMA5A SH3RF3

3.27e-04195754d8ebb94f30d4a655d6b29dd6a3076be2403d2356
ToppCellfacs-Bladder-nan-3m-Epithelial-bladder_mesenchymal_cell_(Car3+)|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D LAMA2 PAM PAPPA

3.27e-0419575418b01ab63ee1deae3cf29669d66fff9ca4efc5c4
ToppCellfacs-Heart-RA-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM NOTCH2

3.27e-04195754690d6e15d7c863fc8f2d33b1f7bf86f019f415c9
ToppCellfacs-Heart-LA-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 LAMA2 PAM NOTCH2

3.27e-0419575479a6e8e6de040ff07539e8901fc407363a50e355
DrugPyrantel tartrate [33401-94-4]; Up 200; 11.2uM; HL60; HG-U133A

TRIM21 EIF4G3 WNK1 NOTCH2 TCTN2 BAHCC1 SOS2

3.56e-061947571413_UP
Diseasehealth-related quality of life measurement

SCN10A SEMA5A

2.21e-049742EFO_0011014
Diseaseopioid dependence

PAPPA BCAR1 CSMD1 CSMD3 CA6

3.29e-04237745EFO_0005611
Diseasecysteine-glutathione disulfide measurement

HNF1A SH3RF3

3.36e-0411742EFO_0021001
Diseasecongenital diaphragmatic hernia (implicated_via_orthology)

WT1 LRP1

4.03e-0412742DOID:3827 (implicated_via_orthology)
DiseaseHereditary Diffuse Gastric Cancer

FCGBP MUC6 NOS3 RNF43 NOTCH2

8.59e-04293745C1708349
DiseaseStomach Neoplasms

FCGBP MUC6 NOS3 RNF43 NOTCH2

9.13e-04297745C0038356
DiseaseMalignant neoplasm of stomach

FCGBP MUC6 NOS3 RNF43 NOTCH2

9.55e-04300745C0024623
Diseasehypertension

BCAR1 BAG6 NOS3 RNF43 SOS2

1.06e-03307745EFO_0000537
Diseasetestosterone measurement

SHROOM4 NCOA6 HNF1A SPEM3 IQSEC2 CCDC85C CHD7 TSC22D2 CSMD3 SOS2

1.27e-0312757410EFO_0004908
DiseaseHMG CoA reductase inhibitor use measurement

HNF1A TSC22D2 BAG6 NOS3

1.32e-03189744EFO_0009932
Diseasemigraine disorder, Headache

LRP1 PAPPA BCAR1

1.33e-0386743HP_0002315, MONDO_0005277
DiseaseMalignant neoplasm of breast

NCOA6 WT1 LAMA2 ETV4 HRG BCAR1 WNK1 NOS3 NOTCH2

1.44e-031074749C0006142
Diseasealbuminuria

CHD7 CSMD1 BAHCC1

1.72e-0394743EFO_0004285
Diseasecortical thickness

ARRDC4 LRP1 LAMA2 PAM CHD7 TSC22D2 EIF4G3 SH3RF3 SOS2

1.83e-031113749EFO_0004840
Diseasediet measurement, bilirubin measurement

LAMA2 SLC38A3

1.94e-0326742EFO_0004570, EFO_0008111
Diseasemaximal oxygen uptake measurement

SCN10A ERBIN

1.94e-0326742EFO_0004887
Diseasemyocardial infarction (is_implicated_in)

LRP1 PAPPA NOS3

2.00e-0399743DOID:5844 (is_implicated_in)
DiseasePancreatic Neoplasm

WT1 BCAR1 RNF43

2.06e-03100743C0030297
DiseaseMalignant neoplasm of pancreas

WT1 BCAR1 RNF43

2.18e-03102743C0346647
DiseaseDiabetes Mellitus, Non-Insulin-Dependent

HNF1A PAM NOS3 NOTCH2

2.34e-03221744C0011860

Protein segments in the cluster

PeptideGeneStartEntry
RPQPCPHYPLAQGDS

CCDC185

131

Q8N715
QPPYTQPHCSPRQGH

ERBIN

1301

Q96RT1
AAQPPAHFQPGKYFP

BAHCC1

36

Q9P281
NGVHPYPAQSPAAPV

CELF3

301

Q5SZQ8
GCIAPSPPASHYVPQ

ALG13

1121

Q9NP73
AYELQNCPDPPPFQN

CSMD1

2081

Q96PZ7
NCPDPPPFQNGYMIN

CSMD1

2086

Q96PZ7
SYHAYQLRVCQPPPP

CSMD3

2386

Q7Z407
LPYLQCRGGPQPQHS

BAG6

186

P46379
QPGLHAPAPPASQYT

BCAR1

86

P56945
SGLCIQPPPYPGNIF

ADAM20

391

O43506
FSCLYGNGPHPPAPQ

ASB2

506

Q96Q27
QSPQLPQAFYPVGHP

PAM

261

P19021
PGSPPPAQQNQYVHI

ATXN1

236

P54253
PQHYPACGGQRQSPI

CA6

36

P23280
HPGQQPSFQQLPTCP

CHD7

501

Q9P2D1
NGPASPPQPSHQQPY

EAF1

216

Q96JC9
GHSPSPPDQQPIYFR

ATG2A

1651

Q2TAZ0
EFSRHIPPYPQPPNC

ARRDC4

361

Q8NCT1
PAPYQHQLSEPCPPY

ETV4

206

P43268
HQLSEPCPPYPQQSF

ETV4

211

P43268
CPEQYTQPPPAQSHR

INTS9

471

Q9NV88
YPGPGHCHQQLNSLP

LGALS4

166

P56470
FLPYPPRSCPQGQAA

FASTK

451

Q14296
HYQPCLCPSQPQSVP

MUC6

1156

Q6W4X9
PQRQPPYYSCQCAPP

NOTCH2

1391

Q04721
HLFGPNQRPAPCYDP

PLD3

66

Q8IV08
FQDYGPCDPPPHNQG

HRG

411

P04196
RLPPIPYPNAPCFNN

LSM11

41

P83369
GAYFCPPQPQLTPPN

MAFIP

36

Q8WZ33
TCLANPSYVPPPQCQ

LRP1

841

Q07954
QVYHPSRQPMAPNPC

LRP1

1526

Q07954
ALHAQYCQGPGPAPP

IQSEC2

1266

Q5JU85
PPSYQDSLQNGPACP

CCDC85C

316

A6NKD9
QQIYPPNPCPHSSSC

C9orf131

831

Q5VYM1
VYHQSPGQAPYPGPQ

PDCD6IP

836

Q8WUM4
YCEPPAHAPQPANGS

PLXNB3

1206

Q9ULL4
PQHPNFCEPQDYRPM

CDC25B

531

P30305
PVQFSQPLHPSYQQP

HNF1A

461

P20823
KGVSPNYPRPCQPCH

LAMA2

401

P24043
DPPPPKFHGLYQCTN

PAPPA

1416

Q13219
HQTLYHPDQPPQCAP

ITFG2

426

Q969R8
LQYQPGDHIGVCPPN

NOS3

791

P29474
HPPPPYPFGSQQASQ

NCOA6

371

Q14686
QGISQLPQYNNCPPP

ERVK-19

646

Q9YNA8
QGISQLPQYNNCPPP

ERVK-21

646

P62683
QGISQLPQYNNCPPP

ERVK-6

646

Q7LDI9
QGISQLPQYNNCPPP

ERVK-7

646

P63130
QGISQLPQYNNCPPP

ERVK-9

646

P63126
QGISQLPQYNNCPPP

HERVK_113

646

P62684
PQQNYKPSPTLYHCP

DNAH6

4096

Q9C0G6
LAPCHGLVPPAQYFQ

FCGBP

2276

Q9Y6R7
PLAPCHGLVPPAQYF

FCGBP

3476

Q9Y6R7
YPNSQPQVHLVPGNP

MS4A8

36

Q9BY19
TFIPGLNPQNPHYIP

FAM166B

6

A8MTA8
PQGPQYCIPQYRHSG

EIF4G3

61

O43432
YFIQAGTQPAPCPRP

KIF28P

401

B7ZC32
GYPPSPQAGLLCPQH

PARP6

226

Q2NL67
CPFQYHGQPIYPGPL

FAM181A

276

Q8N9Y4
SPYCGPYSLRNQPHP

PYGO1

116

Q9Y3Y4
PYSLRNQPHPFPQNP

PYGO1

121

Q9Y3Y4
CSVQHLPVPYAAFPP

RNF38

251

Q9H0F5
FHVPCPLPPNFNNTT

SLC38A3

236

Q99624
HFINCPFNLQPPPLG

SOS2

1226

Q07890
QFAYPQPQIPPGHLL

TSC22D2

356

O75157
QIPQSAYHSPPPSQC

TAB3

286

Q8N5C8
QPPQPCSSPSNPRYH

RECQL4

306

O94761
CNGLPYPSQEHGPQV

FOXN1

181

O15353
PCPYPHCQVLSAQPG

RNF43

756

Q68DV7
ALGPQPHFPQPRYCC

RNF224

126

P0DH78
GHLGSQPEQAQPPCY

SHROOM4

1221

Q9ULL8
PPLPSNFPVGPCFYQ

SCAMP1

121

O15126
QPQDPASSVCPQPHY

DIS3

51

Q9Y2L1
GPPPVNNVASSHAPY

SEC24D

86

O94855
QGISQLPQYNNCPPP

ERVK-9

646

P63128
LPYPNPNPHFQCGTV

SEMA5A

346

Q13591
APPQSYQCPPSQIGE

AURKAIP1

96

Q9NWT8
HPILCHSVYQPPQPA

NDUFV1-DT

61

Q8NBR9
PHYQQAPGGPQFLLP

PRR22

131

Q8IZ63
GSVAPPREQPHQNPY

SUN5

361

Q8TC36
PGLPQDSYLCQNPSP

SPEM3

726

A0A1B0GUW6
LNTGPPYCDPNLPNS

SCN10A

1671

Q9Y5Y9
SYIQCIQPLPHAPPQ

SH3RF3

246

Q8TEJ3
IQLPNIYPAVPPHFC

UBE2O

1006

Q9C0C9
QQYSVPPPVYGCHTP

WT1

191

P19544
GTYPQTPLHLQVPPC

TRIM21

391

P19474
QPPQHLQCPLYRPDS

SOCS7

371

O14512
CPPQQYGFPATPFGA

WNK1

2321

Q9H4A3
PNQVYQPLGPCPCNL

TCTN2

161

Q96GX1
LNELYCPVQFTPPHP

TTI1

1046

O43156