Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	extrinsic component of postsynaptic density membrane	OLFM1 DGKB	7.54e-04	10	87	2	GO:0099147
GeneOntologyCellularComponent	microtubule organizing center attachment site	SPAG4 SYNE2	9.19e-04	11	87	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SPAG4 SYNE2	9.19e-04	11	87	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SPAG4 SYNE2	9.19e-04	11	87	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SPAG4 SYNE2	9.19e-04	11	87	2	GO:0106094
GeneOntologyCellularComponent	extrinsic component of postsynaptic specialization membrane	OLFM1 DGKB	1.10e-03	12	87	2	GO:0098892
Domain	Homez_dom	ZHX3 ZHX1	6.27e-05	3	86	2	IPR024578
Domain	Fork-head_N	FOXA1 FOXA2	6.27e-05	3	86	2	IPR013638
Domain	Forkhead_N	FOXA1 FOXA2	6.27e-05	3	86	2	PF08430
Domain	Homez	ZHX3 ZHX1	6.27e-05	3	86	2	PF11569
Domain	HNF_C	FOXA1 FOXA2	6.27e-05	3	86	2	PF09354
Domain	Forkhead_box_C	FOXA1 FOXA2	6.27e-05	3	86	2	IPR018533
Pubmed	Characterization of Sleeping Beauty transposition and its application to genetic screening in mice.	ADGRB3 DGKB ADD2	8.39e-07	8	87	3	14645530
Pubmed	Role of the CD5 molecule on TCR gammadelta T cell-mediated immune functions: development of germinal centers and chronic intestinal inflammation.	AARS1 CD5	6.19e-06	2	87	2	12502730
Pubmed	Foxa1 and Foxa2 interact with the androgen receptor to regulate prostate and epididymal genes differentially.	FOXA1 FOXA2	6.19e-06	2	87	2	16467259
Pubmed	NDR functions as a physiological YAP1 kinase in the intestinal epithelium.	STK38 STK38L	6.19e-06	2	87	2	25601544
Pubmed	The pioneer transcription factors Foxa1 and Foxa2 regulate alternative RNA splicing during thymocyte positive selection.	FOXA1 FOXA2	6.19e-06	2	87	2	34323272
Pubmed	Transcription factors FOXA1 and FOXA2 maintain dopaminergic neuronal properties and control feeding behavior in adult mice.	FOXA1 FOXA2	6.19e-06	2	87	2	26283356
Pubmed	Pioneer Factors FOXA1 and FOXA2 Assist Selective Glucocorticoid Receptor Signaling in Human Endometrial Cells.	FOXA1 FOXA2	6.19e-06	2	87	2	28938408
Pubmed	Differential induction of HNF-3 transcription factors during neuronal differentiation.	FOXA1 FOXA2	6.19e-06	2	87	2	9260895
Pubmed	Hepatic deficiency of the pioneer transcription factor FoxA restricts hepatitis B virus biosynthesis by the developmental regulation of viral DNA methylation.	FOXA1 FOXA2	6.19e-06	2	87	2	28235042
Pubmed	Sequence logic at enhancers governs a dual mechanism of endodermal organ fate induction by FOXA pioneer factors.	FOXA1 FOXA2	6.19e-06	2	87	2	34789735
Pubmed	Transcription factors Foxa1 and Foxa2 are required for adult dopamine neurons maintenance.	FOXA1 FOXA2	6.19e-06	2	87	2	25249938
Pubmed	Foxa1 and Foxa2 are essential for sexual dimorphism in liver cancer.	FOXA1 FOXA2	6.19e-06	2	87	2	22265403
Pubmed	Immunohistochemical localization of Foxa1 and Foxa2 in mouse embryos and adult tissues.	FOXA1 FOXA2	6.19e-06	2	87	2	15567715
Pubmed	The evolutionarily ancient FOXA transcription factors shape the murine gut microbiome via control of epithelial glycosylation.	FOXA1 FOXA2	6.19e-06	2	87	2	38821056
Pubmed	FOXA1/2 depletion drives global reprogramming of differentiation state and metabolism in a human liver cell line and inhibits differentiation of human stem cell-derived hepatic progenitor cells.	FOXA1 FOXA2	6.19e-06	2	87	2	36515690
Pubmed	Foxa1 and Foxa2 control the differentiation of goblet and enteroendocrine L- and D-cells in mice.	FOXA1 FOXA2	6.19e-06	2	87	2	19737569
Pubmed	Foxa2 and Nurr1 synergistically yield A9 nigral dopamine neurons exhibiting improved differentiation, function, and cell survival.	NR4A2 FOXA2	6.19e-06	2	87	2	20049900
Pubmed	Identification of a regulatory variant that binds FOXA1 and FOXA2 at the CDC123/CAMK1D type 2 diabetes GWAS locus.	FOXA1 FOXA2	6.19e-06	2	87	2	25211022
Pubmed	Combined Nurr1 and Foxa2 roles in the therapy of Parkinson's disease.	NR4A2 FOXA2	6.19e-06	2	87	2	25759364
Pubmed	Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer.	FOXA1 FOXA2	6.19e-06	2	87	2	20160041
Pubmed	Meta-Analysis of Transcriptome Data Related to Hippocampus Biopsies and iPSC-Derived Neuronal Cells from Alzheimer's Disease Patients Reveals an Association with FOXA1 and FOXA2 Gene Regulatory Networks.	FOXA1 FOXA2	6.19e-06	2	87	2	26890743
Pubmed	Negative regulation of hepatitis B virus replication by forkhead box protein A in human hepatoma cells.	FOXA1 FOXA2	6.19e-06	2	87	2	25836733
Pubmed	Nucleosome-binding affinity as a primary determinant of the nuclear mobility of the pioneer transcription factor FoxA.	FOXA1 FOXA2	6.19e-06	2	87	2	19339686
Pubmed	Foxa1 and Foxa2 regulate bile duct development in mice.	FOXA1 FOXA2	6.19e-06	2	87	2	20347503
Pubmed	SPAG4L/SPAG4Lβ interacts with Nesprin2 to participate in the meiosis of spermatogenesis.	SPAG4 SYNE2	6.19e-06	2	87	2	31144711
Pubmed	Foxa (HNF3) up-regulates vitronectin expression during retinoic acid-induced differentiation in mouse neuroblastoma Neuro2a cells.	FOXA1 FOXA2	6.19e-06	2	87	2	12441652
Pubmed	Regulation of NDR2 protein kinase by multi-site phosphorylation and the S100B calcium-binding protein.	STK38 STK38L	6.19e-06	2	87	2	15037617
Pubmed	Foxa1 and Foxa2 in thymic epithelial cells (TEC) regulate medullary TEC and regulatory T-cell maturation.	FOXA1 FOXA2	6.19e-06	2	87	2	30061015
Pubmed	Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.	CPA1 FOXA1 FOXA2	8.27e-06	16	87	3	19141476
Pubmed	Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.	NR4A2 FOXA1 FOXA2	8.27e-06	16	87	3	17596284
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ZHX3 FRAS1 CKAP5 DGKB PPIP5K1 SUZ12 CAMTA1 R3HDM1	8.57e-06	407	87	8	12693553
Pubmed	Jumonji modulates polycomb activity and self-renewal versus differentiation of stem cells.	STK38 SUZ12 STK38L	1.20e-05	18	87	3	20064376
Pubmed	Pancreas-specific deletion of mouse Gata4 and Gata6 causes pancreatic agenesis.	CPA1 FOXA1 FOXA2	1.42e-05	19	87	3	23006325
Pubmed	Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.	NR4A2 FOXA1 FOXA2	1.67e-05	20	87	3	23637192
Pubmed	FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth.	FOXA1 FOXA2	1.85e-05	3	87	2	27045898
Pubmed	Differential distribution of phospholipase C beta isoforms and diaglycerol kinase-beta in rodents cerebella corroborates the division of unipolar brush cells into two major subtypes.	PLCB1 DGKB	1.85e-05	3	87	2	23503970
Pubmed	Human NDR kinases control G(1)/S cell cycle transition by directly regulating p21 stability.	STK38 STK38L	1.85e-05	3	87	2	21262772
Pubmed	MST2- and Furry-mediated activation of NDR1 kinase is critical for precise alignment of mitotic chromosomes.	FRY STK38	1.85e-05	3	87	2	19327996
Pubmed	MID1 and MID2 homo- and heterodimerise to tether the rapamycin-sensitive PP2A regulatory subunit, alpha 4, to microtubules: implications for the clinical variability of X-linked Opitz GBBB syndrome and other developmental disorders.	IGBP1 MID2	1.85e-05	3	87	2	11806752
Pubmed	Cyclin D1 promotes cell cycle progression through enhancing NDR1/2 kinase activity independent of cyclin-dependent kinase 4.	STK38 STK38L	1.85e-05	3	87	2	23897809
Pubmed	The human HNF-3 genes: cloning, partial sequence and mutation screening in patients with impaired glucose homeostasis.	FOXA1 FOXA2	1.85e-05	3	87	2	10899756
Pubmed	FoxO1 and FoxA1/2 form a complex on DNA and cooperate to open chromatin at insulin-regulated genes.	FOXA1 FOXA2	1.85e-05	3	87	2	30142277
Pubmed	FoxA-dependent demethylation of DNA initiates epigenetic memory of cellular identity.	FOXA1 FOXA2	1.85e-05	3	87	2	33636105
Pubmed	Protein or amino acid deprivation differentially regulates the hepatic forkhead box protein A (FOXA) genes through an activating transcription factor-4-independent pathway.	FOXA1 FOXA2	1.85e-05	3	87	2	19415718
Pubmed	Expression and prognostic significance of zinc fingers and homeoboxes family members in renal cell carcinoma.	ZHX3 ZHX1	1.85e-05	3	87	2	28152006
Pubmed	Hepatocyte nuclear factor 3 alpha belongs to a gene family in mammals that is homologous to the Drosophila homeotic gene fork head.	FOXA1 FOXA2	1.85e-05	3	87	2	1672118
Pubmed	The HNF-3 gene family of transcription factors in mice: gene structure, cDNA sequence, and mRNA distribution.	FOXA1 FOXA2	1.85e-05	3	87	2	8034310
Pubmed	Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells.	FOXA1 FOXA2	1.85e-05	3	87	2	18336786
Pubmed	Assignment of the human genes for hepatocyte nuclear factor 3-alpha, -beta, and -gamma (HNF3A, HNF3B, HNF3G) to 14q12-q13, 20p11, and 19q13.2-q13.4.	FOXA1 FOXA2	1.85e-05	3	87	2	9119385
Pubmed	Postimplantation expression patterns indicate a role for the mouse forkhead/HNF-3 alpha, beta and gamma genes in determination of the definitive endoderm, chordamesoderm and neuroectoderm.	FOXA1 FOXA2	1.85e-05	3	87	2	8187630
Pubmed	Foxa1 and Foxa2 regulate bile duct development in mice.	FOXA1 FOXA2	1.85e-05	3	87	2	19436110
Pubmed	Exon-I is involved in positive as well as negative regulation of human angiotensinogen gene expression.	FOXA1 FOXA2	1.85e-05	3	87	2	9931457
Pubmed	Molecular mechanisms of liver development and differentiation.	FOXA1 FOXA2	1.85e-05	3	87	2	10600708
Pubmed	Loss of Interdependent Binding by the FoxO1 and FoxA1/A2 Forkhead Transcription Factors Culminates in Perturbation of Active Chromatin Marks and Binding of Transcriptional Regulators at Insulin-sensitive Genes.	FOXA1 FOXA2	1.85e-05	3	87	2	26929406
Pubmed	Genetic fine mapping and genomic annotation defines causal mechanisms at type 2 diabetes susceptibility loci.	FOXA1 FOXA2	1.85e-05	3	87	2	26551672
Pubmed	Forkhead box A1 (FOXA1) and A2 (FOXA2) oppositely regulate human type 1 iodothyronine deiodinase gene in liver.	FOXA1 FOXA2	1.85e-05	3	87	2	22067325
Pubmed	Chromatin remodeling mediated by the FOXA1/A2 transcription factors activates CFTR expression in intestinal epithelial cells.	FOXA1 FOXA2	1.85e-05	3	87	2	24440874
Pubmed	HIV-1 incorporates and proteolytically processes human NDR1 and NDR2 serine-threonine kinases.	STK38 STK38L	1.85e-05	3	87	2	15582665
Pubmed	Hepatocyte nuclear factor 3/fork head or "winged helix" proteins: a family of transcription factors of diverse biologic function.	FOXA1 FOXA2	1.85e-05	3	87	2	8248124
Pubmed	The initiation of liver development is dependent on Foxa transcription factors.	FOXA1 FOXA2	1.85e-05	3	87	2	15959514
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ZHX3 SYNE2 ADGRB3 PLCB1 CAMTA1 STK38L	2.24e-05	225	87	6	12168954
Pubmed	NDR kinase is activated by RASSF1A/MST1 in response to Fas receptor stimulation and promotes apoptosis.	STK38 STK38L	3.70e-05	4	87	2	19062280
Pubmed	Hepatocyte-specific HDAC3 ablation promotes hepatocellular carcinoma in females by suppressing Foxa1/2.	FOXA1 FOXA2	3.70e-05	4	87	2	37752418
Pubmed	Mechanism of activation of NDR (nuclear Dbf2-related) protein kinase by the hMOB1 protein.	STK38 STK38L	3.70e-05	4	87	2	15197186
Pubmed	MID1, mutated in Opitz syndrome, encodes an ubiquitin ligase that targets phosphatase 2A for degradation.	IGBP1 MID2	3.70e-05	4	87	2	11685209
Pubmed	ErbB3 binding protein 1 represses metastasis-promoting gene anterior gradient protein 2 in prostate cancer.	FOXA1 FOXA2	3.70e-05	4	87	2	20048076
Pubmed	Integrative genomic analysis identifies that SERPINA6-rs1998056 regulated by FOXA/ERα is associated with female hepatocellular carcinoma.	FOXA1 FOXA2	3.70e-05	4	87	2	25198130
Pubmed	The circadian E3 ligase FBXL21 regulates myoblast differentiation and sarcomere architecture via MYOZ1 ubiquitination and NFAT signaling.	MYOZ1 FBXL21P	3.70e-05	4	87	2	36574402
Pubmed	Overexpression of transcription factor FoxA2 in the developing skeleton causes an enlargement of the cartilage hypertrophic zone, but it does not trigger ectopic differentiation in immature chondrocytes.	FOXA1 FOXA2	3.70e-05	4	87	2	35398294
Pubmed	The expression of p21 is upregulated by forkhead box A1/2 in p53-null H1299 cells.	FOXA1 FOXA2	3.70e-05	4	87	2	25281925
Pubmed	Association between hepatocyte nuclear factor 6 (HNF-6) and FoxA2 DNA binding domains stimulates FoxA2 transcriptional activity but inhibits HNF-6 DNA binding.	FOXA1 FOXA2	3.70e-05	4	87	2	12509444
Pubmed	Collapse of the hepatic gene regulatory network in the absence of FoxA factors.	FOXA1 FOXA2	3.70e-05	4	87	2	32561546
Pubmed	The ratio of FoxA1 to FoxA2 in lung adenocarcinoma is regulated by LncRNA HOTAIR and chromatin remodeling factor LSH.	FOXA1 FOXA2	3.70e-05	4	87	2	26658322
Pubmed	Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling.	ADGRB3 PLCB1 R3HDM1 STK38L TNS1 FBXL21P	5.57e-05	265	87	6	19240061
Pubmed	Genome-wide characterisation of Foxa1 binding sites reveals several mechanisms for regulating neuronal differentiation in midbrain dopamine cells.	NR4A2 FOXA1 FOXA2	5.85e-05	30	87	3	25804738
Pubmed	Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues.	FOXA1 FOXA2	6.16e-05	5	87	2	9032290
Pubmed	Ndr kinases regulate retinal interneuron proliferation and homeostasis.	STK38 STK38L	6.16e-05	5	87	2	30135513
Pubmed	Foxa1 and Foxa2 orchestrate development of the urethral tube and division of the embryonic cloaca through an autoregulatory loop with Shh.	FOXA1 FOXA2	6.16e-05	5	87	2	32645357
Pubmed	Differentiation of human epidermal neural crest stem cells (hEPI-NCSC) into virtually homogenous populations of dopaminergic neurons.	NR4A2 FOXA2	6.16e-05	5	87	2	24399192
Pubmed	ZHX proteins regulate podocyte gene expression during the development of nephrotic syndrome.	ZHX3 ZHX1	6.16e-05	5	87	2	17056598
Pubmed	FoxA1 and FoxA2 drive gastric differentiation and suppress squamous identity in NKX2-1-negative lung cancer.	FOXA1 FOXA2	6.16e-05	5	87	2	30475207
Pubmed	A hepatocyte nuclear factor-3 site in the fibrinogen beta promoter is important for interleukin 6-induced expression, and its activity is influenced by the adjacent -148C/T polymorphism.	FOXA1 FOXA2	6.16e-05	5	87	2	15737987
Pubmed	Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases.	STK38 STK38L	6.16e-05	5	87	2	15067004
Pubmed	FoxA proteins regulate H19 endoderm enhancer E1 and exhibit developmental changes in enhancer binding in vivo.	FOXA1 FOXA2	6.16e-05	5	87	2	15485926
Pubmed	Chronological expression of Ciliated Bronchial Epithelium 1 during pulmonary development.	FOXA1 FOXA2	6.16e-05	5	87	2	19213785
Pubmed	Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.	FOXA1 FOXA2	6.16e-05	5	87	2	17220277
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	THAP4 DCHS2 AARS1 FRY LONRF1 NR4A2 CKAP5 ADGRB3 OLFM1 DNAJB9 R3HDM1 ADARB1	8.46e-05	1285	87	12	35914814
Pubmed	Foxa2 activity increases plasma high density lipoprotein levels by regulating apolipoprotein M.	FOXA1 FOXA2	9.22e-05	6	87	2	18381283
Pubmed	The zinc finger-containing transcription factor Gata-4 is expressed in the developing endocrine pancreas and activates glucagon gene expression.	FOXA1 FOXA2	9.22e-05	6	87	2	15539431
Pubmed	Differential expression of multiple fork head related genes during gastrulation and axial pattern formation in the mouse embryo.	FOXA1 FOXA2	9.22e-05	6	87	2	8375339
Pubmed	Loss of NDR1/2 kinases impairs endomembrane trafficking and autophagy leading to neurodegeneration.	STK38 STK38L	9.22e-05	6	87	2	36446521
Pubmed	Expression of Foxa transcription factors in the developing and adult murine prostate.	FOXA1 FOXA2	9.22e-05	6	87	2	15389796
Pubmed	Subclassification of the RBCC/TRIM superfamily reveals a novel motif necessary for microtubule binding.	IGBP1 MID2	9.22e-05	6	87	2	16434393
Pubmed	Nurr1 is essential for the induction of the dopaminergic phenotype and the survival of ventral mesencephalic late dopaminergic precursor neurons.	NR4A2 FOXA2	9.22e-05	6	87	2	9520484
Pubmed	Foxa1 is essential for development and functional integrity of the subthalamic nucleus.	FOXA1 FOXA2	1.29e-04	7	87	2	27934886
Pubmed	Expression of mouse dchs1, fjx1, and fat-j suggests conservation of the planar cell polarity pathway identified in Drosophila.	DCHS2 FAT2	1.29e-04	7	87	2	16059920
Pubmed	FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.	FOXA1 FOXA2	1.29e-04	7	87	2	35835117
Pubmed	Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis.	FOXA1 FOXA2	1.29e-04	7	87	2	10479450
Pubmed	Members of the HNF-3/forkhead family of transcription factors exhibit distinct cellular expression patterns in lung and regulate the surfactant protein B promoter.	FOXA1 FOXA2	1.29e-04	7	87	2	7958446
Pubmed	The winged-helix transcription factor HNF-3 beta is required for notochord development in the mouse embryo.	FOXA1 FOXA2	1.72e-04	8	87	2	8069910
GeneFamily	Zinc fingers C2H2-type\|ZF class homeoboxes and pseudogenes	ZHX3 ZHX1	8.64e-04	15	53	2	529
GeneFamily	Cadherin related	DCHS2 FAT2	1.11e-03	17	53	2	24
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-skeletal_muscle_satellite_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TOR1AIP2 ZHX3 AARS1 DNAJB9 EIF1 ADARB1	2.46e-06	197	87	6	5bc11aff92da2a0aca8473f997fe7a99f3cae75d
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DUSP26 FRY MYOZ1 NR4A2 STK38L TNS1	2.68e-06	200	87	6	2bc7f462a551292de2501028164573935232f899
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-2m-Neuronal-Intermediate\|2m / Sample Type, Dataset, Time_group, and Cell type.	DUSP26 FRY SYNE2 NR4A2 OLFM1 FOXA2	2.68e-06	200	87	6	2a635694844ddabcd98462c5636a6f41a3f08a46
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DUSP26 FRY MYOZ1 NR4A2 STK38L TNS1	2.68e-06	200	87	6	8b80a65b69b36ed405214564b939452c90aa40d6
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	POLM PPIP5K1 TUBD1 CCDC180 NEURL4	1.38e-05	156	87	5	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 MUC16 CPA1 GRIK5 ADD2	1.86e-05	166	87	5	4d63c758d46e73311b864148c646bf081498dee7
ToppCell	368C-Fibroblasts-Fibroblast-J_(Lipofibroblast)\|368C / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 MUC16 CPA1 GRIK5 ADD2	1.86e-05	166	87	5	4160ccf9291072a6e2782f9ad141bc9a9747f3ad
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RNASE1 SPAG4 CPA1 SLC45A1 FOXA1	1.86e-05	166	87	5	b7f303203068b205f382788815df487a0ea148ed
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	RNASE1 POLM FSD1 CAMTA1	2.69e-05	88	87	4	142d2e00ef19c0ad011a21945bf1111271056eae
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FRAS1 FRY UGT3A1 NR4A2 MCCC1	3.13e-05	185	87	5	a0a629e5d2b65f670ea907bd3f5e3caf17687d8f
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ZHX3 FRAS1 SYNE2 PLCB1 TNS1	3.21e-05	186	87	5	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	IPF-Stromal-SMC\|Stromal / Disease state, Lineage and Cell class	DUSP26 FRY MYOZ1 PLCB1 DGKB	3.74e-05	192	87	5	9b06c7336624ef21f8e5393725b56038a8028e57
ToppCell	368C-Fibroblasts-Fibroblast-K_(Pericytes)\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DUSP26 FRY MYOZ1 SYNE2 STK38L	3.83e-05	193	87	5	5260ac95a15cc43a19909badad0c7e3854da920d
ToppCell	Thalamus-Neuronal\|Thalamus / BrainAtlas - Mouse McCarroll V32	SPAG4 TRANK1 SLC45A1 CAMTA1 ADD2	3.83e-05	193	87	5	712a4acd1167e43543950bc819ff11984e6f718d
ToppCell	368C-Fibroblasts-Fibroblast-K_(Pericytes)-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DUSP26 FRY MYOZ1 SYNE2 STK38L	3.83e-05	193	87	5	5ec917931b438dd0e7fb03eb6af459d3ef6b84ba
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DUSP26 FRY MYOZ1 DGKB TNS1	4.02e-05	195	87	5	5dc874641ad9537e4c1369825c1fb0a59f12a83d
ToppCell	Endothelial\|World / shred by cell class for bronchial biopsy	FRY RNASE1 OLFM1 ADARB1 IPO11	4.02e-05	195	87	5	f0e46e859f7a9bdead3203889f7e20fa21f76ff0
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRY ADGRB3 PLCB1 OLFM1 R3HDM1	4.12e-05	196	87	5	676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCell	COVID-19-Lymphoid-CD4_T_cells\|Lymphoid / Condition, Lineage and Cell class	FRY CD5 MID2 PLCB1 EIF1	4.12e-05	196	87	5	28515d8e2f02366fa0ac1bea251a7a3f659c98c7
ToppCell	COVID_non-vent-Lymphocytic-T_cell-CD8+_Memory_T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	CD5 TRANK1 SYNE2 SSBP3 PARP15	4.22e-05	197	87	5	836061acd7f0d5de89b16f52ec679bdf09eac9db
ToppCell	Parenchyma_Control_(B.)-Immune-TX-MoAM-4\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	GTF2H2 STK38L NEURL4 CCDC93 POLR3F	4.22e-05	197	87	5	dc1c55e3aacc9d60d0f111c2f20f150ca296f011
ToppCell	Parenchymal-10x3prime_v2-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	DUSP26 MYOZ1 DGKB PPIP5K1 TNS1	4.22e-05	197	87	5	470e23dee4ca35e1fd021b7cdd58fcbc90639837
ToppCell	Somatosensory_Cortex_(S1)-Neuronal\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRY ADGRB3 PLCB1 OLFM1 R3HDM1	4.33e-05	198	87	5	c01091ef18e096d792ea2a7a715764a5b215355f
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	FRY ADGRB3 PLCB1 OLFM1 R3HDM1	4.33e-05	198	87	5	8ab40fae14fe02e39bc8c8da187a5cd60c787643
ToppCell	10x_5'_v1-Non-neoplastic-Lymphoid-CD4/CD8-CD8_NK_sig-Z\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SYNE2 NR4A2 STK38 PLCB1 KIR3DL1	4.43e-05	199	87	5	0902b08e3386e64d7347c186d9ce5b67f2deaabb
ToppCell	mild-NK\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	SYNE2 FSD1 SSBP3 KIR3DL1 PARP15	4.54e-05	200	87	5	a11fb1d7e124c352eb73fea0e0ec0fed577c97f7
Disease	phosphatidylcholine measurement	CEP120 PPT2 SYNE2 PLCB1 GRIK5	1.06e-03	284	80	5	EFO_0010226
Disease	Bipolar Disorder	TRANK1 NR4A2 PLCB1 DGKB GRIK5 ADARB1	1.90e-03	477	80	6	C0005586
Disease	hair shape measurement	FRAS1 ADD2	2.44e-03	27	80	2	EFO_0007824

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASFPSDTFHTMNTQQ	ZNF280B	201	Q86YH2
TFFPNSEFLHSCVMS	ABRAXAS1	286	Q6UWZ7
SNMELSLDHFDISFS	CAMTA1	756	Q9Y6Y1
TFLTSDMISAHPFTN	ADGRG4	2041	Q8IZF6
ADSSSSFPNGHAQIM	ADGRB3	1171	O60242
TNPDGFAFTHSTNRM	CPA1	221	P15085
SMQPDNSSDSDYDLH	CD5	476	P06127
QSFSEFMASESIHTP	CCDC180	361	Q9P1Z9
MFSFSGFDSTNQHTV	DNAJB9	176	Q9UBS3
LSASSFQFNQHLMDS	CDAN1	576	Q8IWY9
TSLPFHTYSNMNEDL	ADAMTS20	211	P59510
ESPTRLAQQSHMDAF	POLM	371	Q9NP87
SQFSHMSLARQPSAD	R3HDM1	546	Q15032
ANPNRSFSDVHTMDL	RABEPK	56	Q7Z6M1
TASSHGPQMQDAFLS	RIC1	1186	Q4ADV7
SDHPTPSDSQAEMQF	PCDHGB7	676	Q9Y5F8
NVSPFTAASSFHMQQ	MAML1	856	Q92585
MSDSNLSDNHLPDTF	OR52D1	1	Q9H346
HGATSQDTFTMDPSN	MUC16	4981	Q8WXI7
QPNSTHFFDTDKMAS	OR8K5	261	Q8NH50
FQSTFSMTTCNLPEH	PARP15	471	Q460N3
DNTPFTSVNHMVLDS	FRAS1	3246	Q86XX4
PAFMFRLDASTSHQN	FSD1	266	Q9BTV5
PFDFHSVMEESQSLN	LONRF1	351	Q17RB8
QNTSFFSSLLNEMAH	IPO11	801	Q9UI26
AAFPSAMSHRNRSFS	FAM184B	936	Q9ULE4
HQSQSSSSFPFIYMD	FRMD7	406	Q6ZUT3
MSAIQNLHSFDPFAD	EIF1	1	P41567
FQESFNMSPVTTAHA	KIR3DL1	76	P43629
AFNTRSEMFAIHPTS	FAT2	186	Q9NYQ8
NHTANSSMAYPSLVA	IGBP1	136	P78318
MPIANDTQFHTSSFL	OR52E6	1	Q96RD3
EAAVDFSNYHSPSSM	PDE6A	41	P16499
FSNYHSPSSMEESEI	PDE6A	46	P16499
VDFMNTDNFTSHRLP	OLFM1	281	Q99784
SPSDQEMNEDFSLHS	OBI1	616	Q5W0B1
MNSGHSFSQTPSASF	KRT23	1	Q9C075
SEFSSHSNKALMAPN	PAXBP1	496	Q9Y5B6
SFVQFPNASEAHLAM	ADARB1	141	P78563
DDNDHAPQFMFSSFS	DCHS2	2761	Q6V1P9
MIFPSHDSQAFTSVD	OR9G4	1	Q8NGQ1
DHNVDSFISLSSPQM	PPT2	126	Q9UMR5
SGPHDQIMSSAFQAS	POMT1	291	Q9Y6A1
FNHPFSINNLMSSSE	FOXA1	396	P55317
SIHENFSQAMASPAA	CCDC93	541	Q567U6
FDDMHSNTASTINFI	CKAP5	1531	Q14008
AFDFATMPHQLQDTF	CEP120	511	Q8N960
PDDFTAHLFMSFSNK	DGKB	76	Q9Y6T7
AMTDTFTLQAHDQFS	MCCC1	521	Q96RQ3
ISFMHSSFQPACSDF	KRTAP25-1	76	Q3LHN0
PHSFNTRMSSFDASL	FRY	2566	Q5TBA9
SSNILGFSMFNTSHP	GRIK5	261	Q16478
LMDFSADSADNPSHA	SLC45A1	236	Q9Y2W3
FPNSLESHNDFANME	NEURL4	256	Q96JN8
PSFMNVSESHFVSAL	FBXL21P	156	Q9UKT6
AFNHPFSINNLMSSE	FOXA2	371	Q9Y261
AHVDSNPAMTSLDYS	NR4A2	371	P43354
SLSDQDAKPSFSMAH	GTF2H2C;	261	Q6P1K8
HSLPSDFTFQNMNSK	STK38	251	Q15208
FTNSDTPTSFNHMDS	TOR1AIP2	426	Q8NFQ8
FLHSFQNDNYSPSMT	SSBP3	371	Q9BWW4
THNPPSDFSFQNMNS	STK38L	251	Q9Y2H1
QTTTSFQNMAFQDHP	SYNE2	3601	Q8WXH0
SAQFSLEHMSPDQAD	SYNE2	4016	Q8WXH0
AIEMSSLSEFHQSSF	SGO2	121	Q562F6
NPMIQRNSSFASSHE	POLR3F	201	Q9H1D9
FQRQHMDSDSSPSSS	RNASE1	36	P07998
HTPNFFSENSSMSIT	SPAG4	16	Q9NPE6
SPAFDMSIHFQTAAD	DUSP26	121	Q9BV47
ADFMASTSHAVFPTS	ADD2	91	P35612
SCSSQQEFQDHMSEP	CIZ1	601	Q9ULV3
NIPHMSENSLAYTTF	TUBD1	276	Q9UJT1
DMQSTFDNTIKEHFP	UGT3A1	216	Q6NUS8
HSPQTSAMLFTVDNE	AARS1	881	P49588
SPNLTQFTEHFNNMS	RAPGEF1	876	Q13905
FMENHNPINSATSIS	RWDD4	111	Q6NW29
SLSDQDAKPSFSMAH	GTF2H2	261	Q13888
SQPQSHFTDMSFALD	SPATA31D1	1216	Q6ZQQ2
AVSSNEFEPSNSHMV	SUZ12	231	Q15022
HDPSGMFRSQSFSEA	TNS1	611	Q9HBL0
TFQTPDLNMFTFHVD	ZHX1	76	Q9UKY1
SLSDQMDHPDFSSEN	USF3	1021	Q68DE3
TNSHLSNFNMTSLFP	USF3	2181	Q68DE3
EDMSQPLSHYFINSS	PLCB1	316	Q9NQ66
NFMGDAFQHSSQSIP	SLC30A5	386	Q8TAD4
DNNMLSFYDPANSLH	MID2	661	Q9UJV3
HSFSTNMAFNILNDT	TRANK1	986	O15050
MNSEHTDFNKDPTFV	ZHX3	96	Q9H4I2
QPMLNFSFNSFHPDT	THAP4	461	Q8WY91
FDSMHSSQASDNPFS	PPIP5K1	1131	Q6PFW1
PDVFSDSSMDHFQKF	MYOZ1	76	Q9NP98