Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	histone demethylase activity	KDM5C KDM2A FBXL19	2.86e-04	31	83	3	GO:0032452
GeneOntologyMolecularFunction	protein demethylase activity	KDM5C KDM2A FBXL19	3.15e-04	32	83	3	GO:0140457
Domain	Znf_PHD	BAZ2A KDM5C PHF24 DIDO1 KDM2A FBXL19	3.16e-06	91	83	6	IPR001965
Domain	ZF_PHD_2	BAZ2A KDM5C PHF24 DIDO1 KDM2A FBXL19	4.07e-06	95	83	6	PS50016
Domain	ZF_PHD_1	BAZ2A KDM5C PHF24 DIDO1 KDM2A FBXL19	4.32e-06	96	83	6	PS01359
Domain	Zinc_finger_PHD-type_CS	KDM5C PHF24 DIDO1 KDM2A FBXL19	1.03e-05	65	83	5	IPR019786
Domain	Znf_PHD-finger	BAZ2A KDM5C DIDO1 KDM2A FBXL19	2.67e-05	79	83	5	IPR019787
Domain	PHD	BAZ2A KDM5C DIDO1 KDM2A FBXL19	4.75e-05	89	83	5	SM00249
Domain	Znf_FYVE_PHD	BAZ2A KDM5C PHF24 DIDO1 KDM2A FBXL19	4.92e-05	147	83	6	IPR011011
Domain	PHD_4	KDM2A FBXL19	5.84e-05	3	83	2	PF16866
Domain	SPOC_C	RBM15 DIDO1	2.89e-04	6	83	2	IPR012921
Domain	SPOC	RBM15 DIDO1	2.89e-04	6	83	2	PF07744
Domain	Arm	ARVCF PKP3 APC2	3.48e-04	31	83	3	PF00514
Domain	Plakophilin/d_Catenin	ARVCF PKP3	4.04e-04	7	83	2	IPR028435
Domain	ARM_REPEAT	ARVCF PKP3 APC2	7.43e-04	40	83	3	PS50176
Domain	ARM	ARVCF PKP3 APC2	7.43e-04	40	83	3	SM00185
Domain	-	BAZ2A KDM5C PHF24 DIDO1 KDM2A USP39 FBXL19 RNF126	8.55e-04	449	83	8	3.30.40.10
Domain	Znf_RING/FYVE/PHD	BAZ2A KDM5C PHF24 DIDO1 KDM2A USP39 FBXL19 RNF126	9.86e-04	459	83	8	IPR013083
Domain	BAH	TNRC18 BAHCC1	1.05e-03	11	83	2	SM00439
Domain	Znf_CXXC	KDM2A FBXL19	1.05e-03	11	83	2	IPR002857
Domain	ZF_CXXC	KDM2A FBXL19	1.05e-03	11	83	2	PS51058
Domain	BAH	TNRC18 BAHCC1	1.05e-03	11	83	2	PF01426
Domain	BAH	TNRC18 BAHCC1	1.05e-03	11	83	2	PS51038
Domain	zf-CXXC	KDM2A FBXL19	1.05e-03	11	83	2	PF02008
Domain	BAH_dom	TNRC18 BAHCC1	1.05e-03	11	83	2	IPR001025
Domain	Armadillo	ARVCF PKP3 APC2	1.19e-03	47	83	3	IPR000225
Domain	FBOX	FBXW8 KDM2A FBXL19	1.60e-03	52	83	3	SM00256
Domain	Leu-rich_rpt_Cys-con_subtyp	KDM2A FBXL19	3.18e-03	19	83	2	IPR006553
Domain	LRR_CC	KDM2A FBXL19	3.18e-03	19	83	2	SM00367
Domain	F-box	FBXW8 KDM2A FBXL19	3.30e-03	67	83	3	PF00646
Domain	FBOX	FBXW8 KDM2A FBXL19	4.05e-03	72	83	3	PS50181
Domain	PHD	BAZ2A KDM5C DIDO1	4.54e-03	75	83	3	PF00628
Domain	F-box_dom	FBXW8 KDM2A FBXL19	4.54e-03	75	83	3	IPR001810
Domain	JmjC	KDM5C KDM2A	5.05e-03	24	83	2	PF02373
Domain	-	PHLDB3 MAPK8IP1 IQSEC3 PLEKHA6 BCR SPRED3	7.90e-03	391	83	6	2.30.29.30
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	RBM15 LMO7 BAZ2A ATXN7 CSNK1E KDM5C PKP3 BCL7C BAG3 EIF4G1 RBM6 DIDO1 EXOSC2	4.35e-08	774	84	13	15302935
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RBM15 LMO7 KDM5C PKP3 BAG3 EIF4G1 RBM6 DIDO1 PLEKHA6 ANKLE2	3.89e-07	503	84	10	16964243
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	RBM15 RRP36 CSNK1E G3BP2 RPS10 DDX54 RBM6 DIDO1 RP9 EIF3A RRP1 NCOA5	5.50e-07	807	84	12	22681889
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	RBM15 DHX40 BAG3 RPS10 DDX54 RBM6 DIDO1 KDM2A EIF3A USP39 EXOSC2 RRP1 NCOA5	7.12e-07	989	84	13	36424410
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	RBM15 FBXW8 LMO7 RRP36 PKP3 RPS10 EIF4G1 DDX54 EIF3A USP39 AGPS RRP1 NCOA5	1.05e-06	1024	84	13	24711643
Pubmed	Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.	RBM15 TNRC18 ARVCF LMO7 CSNK1E PKP3 G3BP2 BAG3 RPS10 EIF4G1 DDX54 PLEKHA6 EXOSC2 RRP1	1.65e-06	1247	84	14	27684187
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	RBM15 LMO7 CSNK1E PKP3 G3BP2 RPS10 EIF4G1 DDX54 DIDO1 EIF3A USP39 EXOSC2 RRP1 NCOA5	1.81e-06	1257	84	14	36526897
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	RBM15 LMO7 BAZ2A PKP3 RPS10 DDX54 ANKRD11 DIDO1 KDM2A USP39 HDGFL2 EXOSC2 RRP1 NCOA5	2.53e-06	1294	84	14	30804502
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	RBM15 LMO7 BAG3 EIF4G1 DIDO1 EIF3A USP39 RRP1	2.74e-06	361	84	8	26167880
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	RABEP2 RBM15 LMO7 KDM5C DDX54 ANKRD11 USP39 HDGFL2 MINDY1	3.29e-06	497	84	9	36774506
Pubmed	Carcinogenic Helicobacter pylori Strains Selectively Dysregulate the In Vivo Gastric Proteome, Which May Be Associated with Stomach Cancer Progression.	RABEP2 G3BP2	5.76e-06	2	84	2	30455363
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	RBM15 LMO7 G3BP2 RPS10 EIF4G1 DDX54 EIF3A USP39 EXOSC2 RRP1 NCOA5	6.17e-06	847	84	11	35850772
Pubmed	Characterizing ZC3H18, a Multi-domain Protein at the Interface of RNA Production and Destruction Decisions.	RBM15 RRP36 CSNK1E RPS10 DDX54 EIF3A USP39 EXOSC2 RRP1 NCOA5	1.08e-05	731	84	10	29298432
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	G3BP2 EIF4G1 EIF3A USP39	1.30e-05	59	84	4	32382008
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	PHLDB3 BMP8B TNRC18 ARVCF EIF4G1 ANKRD11 NINL SDF4 MARVELD3 FBXL19 BCR BAHCC1	1.37e-05	1105	84	12	35748872
Pubmed	Systematic analysis and nomenclature of mammalian F-box proteins.	FBXW8 LMO7 KDM2A FBXL19	1.49e-05	61	84	4	15520277
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	RBM15 CSNK1E G3BP2 EIF4G1 DDX54 RBM6 DIDO1 EXOSC2 RRP1 NCOA5	1.49e-05	759	84	10	35915203
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	LMO7 TTC39C G3BP2 RPS10 EIF4G1 RBM6 DIDO1	1.54e-05	329	84	7	34316702
Pubmed	CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.	RBM15 RPS10 EIF4G1 DDX54 EIF3A USP39 HDGFL2 RRP1 NCOA5	1.59e-05	605	84	9	28977666
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	RABEP2 PHLDB3 GOLGA6L2 LMO7 BAG3 NINL DCAF11 FBXL19 ANKLE2 BCR RNF126 ATP2B2 EXOSC2	1.65e-05	1321	84	13	27173435
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	BAZ2A BCL7C DDX54 DIDO1 KDM2A USP39 HDGFL2 EXOSC2 RRP1	1.65e-05	608	84	9	36089195
Pubmed	Structural organization of the bcr gene and its role in the Ph' translocation.	BCR EXOSC2	1.73e-05	3	84	2	2989703
Pubmed	Interactome analysis of the human Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 (hMTr1) protein.	G3BP2 RPS10 EIF4G1 EIF3A USP39	2.20e-05	138	84	5	30320910
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	BAZ2A DHX40 G3BP2 RPS10 EIF4G1 SDF4 EIF3A USP39 EXOSC2 NCOA5	2.57e-05	809	84	10	32129710
Pubmed	Nuclear Functions of Nucleolin through Global Proteomics and Interactomic Approaches.	RPS10 USP39 HDGFL2 EXOSC2 RRP1	2.78e-05	145	84	5	27049334
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	RBM15 DHX40 G3BP2 BAG3 EIF4G1 SDF4 EIF3A DCAF11 USP39 BCR TARBP1	3.01e-05	1005	84	11	19615732
Pubmed	The proximal proteome of 17 SARS-CoV-2 proteins links to disrupted antiviral signaling and host translation.	CSNK1E G3BP2 BAG3 RPS10 RBM6 SDF4 RP9 EIF3A USP39 ANKLE2 NCOA5	3.07e-05	1007	84	11	34597346
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	RBM15 KDM5C EIF4G1 DIDO1 KDM2A EIF3A USP39 RNF126 HDGFL2 EXOSC2 NCOA5	3.26e-05	1014	84	11	32416067
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	RBM15 DDX54 USP39 HDGFL2 RRP1 NCOA5	3.38e-05	251	84	6	31076518
Pubmed	Duplication of small segments within the major breakpoint cluster region in chronic myelogenous leukemia.	BCR EXOSC2	3.45e-05	4	84	2	8453102
Pubmed	Structural alterations of the BCR and ABL genes in Ph1 positive acute leukemias with rearrangements in the BCR gene first intron: further evidence implicating Alu sequences in the chromosome translocation.	BCR EXOSC2	3.45e-05	4	84	2	2678002
Pubmed	Entire ABL gene is joined with 5'-BCR in some patients with Philadelphia-positive leukemia.	BCR EXOSC2	3.45e-05	4	84	2	1868241
Pubmed	Characterization and chromosomal localization of PTPRO, a novel receptor protein tyrosine phosphatase, expressed in hematopoietic stem cells.	BMP8B PTPRU	3.45e-05	4	84	2	9434160
Pubmed	A novel variant of the bcr-abl fusion product in Philadelphia chromosome-positive acute lymphoblastic leukemia.	BCR EXOSC2	3.45e-05	4	84	2	2193202
Pubmed	The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript.	BCR EXOSC2	3.45e-05	4	84	2	3023859
Pubmed	Localization of the c-ab1 oncogene adjacent to a translocation break point in chronic myelocytic leukaemia.	BCR EXOSC2	3.45e-05	4	84	2	6316147
Pubmed	Isolation of human oncogene sequences (v-fes homolog) from a cosmid library.	BCR EXOSC2	3.45e-05	4	84	2	6281890
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	RBM15 G3BP2 RPS10 EIF4G1 RBM6 EIF3A	3.94e-05	258	84	6	37794589
Pubmed	BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.	RBM15 LMO7 PKP3 G3BP2 RPS10 EIF4G1 DDX54 EIF3A HDGFL2	5.57e-05	711	84	9	33022573
Pubmed	Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22.	BCR EXOSC2	5.74e-05	5	84	2	6319012
Pubmed	Sequence and analysis of the human ABL gene, the BCR gene, and regions involved in the Philadelphia chromosomal translocation.	BCR EXOSC2	5.74e-05	5	84	2	7665185
Pubmed	Mapping of the mouse corticotropin-releasing hormone receptor 2 gene (Crhr2) to chromosome 6.	USP39 NEUROD6	8.59e-05	6	84	2	9383293
Pubmed	Human INT6/eIF3e is required for nonsense-mediated mRNA decay.	EIF4G1 EIF3A	8.59e-05	6	84	2	17468741
Pubmed	Estrogen receptor α promotes protein synthesis by fine-tuning the expression of the eukaryotic translation initiation factor 3 subunit f (eIF3f).	EIF4G1 EIF3A	8.59e-05	6	84	2	30573685
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	LMO7 RRP36 G3BP2 BAG3 COQ8B NINL EIF3A AGPS EXOSC2	8.72e-05	754	84	9	33060197
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	PHLDB3 RBM15 ARVCF BAZ2A DHX40 BAG3 RPS10 EIF4G1 DDX54 KDM2A EIF3A AGPS	9.72e-05	1353	84	12	29467282
Pubmed	Identification of a family of human F-box proteins.	FBXW8 LMO7 KDM2A	9.95e-05	37	84	3	10531035
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	RABEP2 MAPK8IP1 IQSEC3 ARVCF G3BP2 APC2 EIF4G1 DIDO1 BCR CCDC177	1.10e-04	963	84	10	28671696
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	RRP36 CSNK1E RPS10 DDX54 AGPS BCR EXOSC2	1.18e-04	454	84	7	33226137
Pubmed	Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells.	KDM5C KDM2A	1.20e-04	7	84	2	28262558
Pubmed	Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.	DDX54 USP39 HDGFL2 NCOA5	1.21e-04	104	84	4	26167872
Pubmed	Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.	PKP3 G3BP2 BAG3 RPS10 EIF4G1 DDX54 DIDO1 EIF3A USP39 HDGFL2 EXOSC2 TARBP1	1.48e-04	1415	84	12	28515276
Pubmed	Mechanistic insights into COVID-19 by global analysis of the SARS-CoV-2 3CLpro substrate degradome.	RBM15 EIF4G1 EIF3A	1.56e-04	43	84	3	34672947
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	TNRC18 KDM5C EIF4G1 ANKRD11 KDM2A ANKLE2	1.57e-04	332	84	6	37433992
Pubmed	Erythropoiesis and globin gene expression in mice lacking the transcription factor NF-E2.	NFE2 TFR2	1.60e-04	8	84	2	7567998
Pubmed	Altered White Matter and microRNA Expression in a Murine Model Related to Williams Syndrome Suggests That miR-34b/c Affects Brain Development via Ptpru and Dcx Modulation.	PTPRU NEUROD6	1.60e-04	8	84	2	35011720
Pubmed	mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin.	EIF4G1 EIF3A	1.60e-04	8	84	2	16541103
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	MAPK8IP1 IQSEC3 ARVCF LMO7 G3BP2 RPS10 EIF4G1 EIF3A PLEKHA6 BCR CCDC177 ATP2B2	1.64e-04	1431	84	12	37142655
Pubmed	Poly(ADP-ribosyl)ation of BRD7 by PARP1 confers resistance to DNA-damaging chemotherapeutic agents.	DHX40 G3BP2 EIF4G1 DDX54 EIF3A USP39 EXOSC2	1.79e-04	486	84	7	30940648
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	RBM15 BAZ2A RPS10 EIF4G1 DDX54 RBM6 DIDO1 RRP1	1.84e-04	653	84	8	22586326
Pubmed	The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.	BAZ2A DDX54 EIF3A EXOSC2 RRP1 NCOA5	2.06e-04	349	84	6	25665578
Pubmed	Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification.	RBM15 ATXN7 CSNK1E DHX40 RBM6	2.08e-04	222	84	5	37071664
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	RABEP2 RBM15 LMO7 EIF4G1 DIDO1 KDM2A	2.43e-04	360	84	6	33111431
Pubmed	Upf1 phosphorylation triggers translational repression during nonsense-mediated mRNA decay.	EIF3A EXOSC2	2.56e-04	10	84	2	18423202
Pubmed	DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.	KDM2A FBXL19	2.56e-04	10	84	2	29276034
Pubmed	UBAP2L arginine methylation by PRMT1 modulates stress granule assembly.	G3BP2 EIF4G1	2.56e-04	10	84	2	31114027
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	RBM15 RPS10 EIF4G1 RBM6 DIDO1 USP39 AGPS EXOSC2 RRP1 NCOA5	2.80e-04	1082	84	10	38697112
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	LMO7 KDM5C NINL DIDO1 ANKLE2 BCR MINDY1	2.99e-04	529	84	7	14621295
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	RPS10 EIF3A TNFRSF11A ANKLE2 RRP1 SLC4A2	3.02e-04	375	84	6	32788342
Pubmed	Natural antisense transcripts associated with genes involved in eye development.	VAX2 RAX	3.13e-04	11	84	2	15703187
Pubmed	Ermap, a gene coding for a novel erythroid specific adhesion/receptor membrane protein.	BMP8B PTPRU	3.13e-04	11	84	2	10721728
Pubmed	Single-cell transcriptional analysis reveals developmental stage-dependent changes in retinal progenitors in the murine early optic vesicle.	VAX2 RAX	3.13e-04	11	84	2	33548738
Pubmed	SARS-CoV-2 N Protein Antagonizes Stress Granule Assembly and IFN Production by Interacting with G3BPs to Facilitate Viral Replication.	FBXW8 G3BP2 DDX54 USP39 NCOA5	3.27e-04	245	84	5	35652658
Pubmed	Phosphoproteomic analysis of the developing mouse brain.	ARVCF G3BP2 BCL7C RPS10 AGPS	3.33e-04	246	84	5	15345747
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	DHX40 G3BP2 RPS10 EIF4G1 RBM6 EIF3A USP39 NCOA5	3.35e-04	714	84	8	28302793
Pubmed	Identification of a USP9X Substrate NFX1-123 by SILAC-Based Quantitative Proteomics.	CSNK1E RPS10 EIF4G1 USP39 EXOSC2 RRP1	3.43e-04	384	84	6	31059266
Pubmed	Human Antiviral Protein IFIX Suppresses Viral Gene Expression during Herpes Simplex Virus 1 (HSV-1) Infection and Is Counteracted by Virus-induced Proteasomal Degradation.	BAZ2A G3BP2 RPS10 HDGFL2 NCOA5	3.65e-04	251	84	5	28077445
Pubmed	G3BP-Caprin1-USP10 complexes mediate stress granule condensation and associate with 40S subunits.	G3BP2 EIF4G1	3.75e-04	12	84	2	27022092
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	RBM15 CSNK1E G3BP2 EIF4G1 EIF3A TUSC1 EXOSC2	3.81e-04	551	84	7	34728620
Pubmed	SOX2 hypomorphism disrupts development of the prechordal floor and optic cup.	VAX2 RAX	4.42e-04	13	84	2	22522080
Pubmed	Therapeutic targeting of the USP2-E2F4 axis inhibits autophagic machinery essential for zinc homeostasis in cancer progression.	RBM15 RPS10 EIF4G1 EIF3A RRP1 NCOA5	4.43e-04	403	84	6	35253629
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	LMO7 PKP3 BAG3 RPS10 EIF3A	4.44e-04	262	84	5	36880596
Pubmed	LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.	MAN1A1 BAG3 EIF4G1 ANKLE2 RNF126 TARBP1 MINDY1 RRP1 SLC4A2	4.52e-04	942	84	9	31073040
Pubmed	TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.	RBM15 LMO7 RRP36 PKP3 G3BP2 DDX54 RP9 EIF3A RRP1	4.77e-04	949	84	9	36574265
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	RBM15 BAZ2A RPS10 EIF4G1 ANKRD11 RBM6 DIDO1 RP9 HDGFL2	4.96e-04	954	84	9	36373674
Pubmed	Defining the membrane proteome of NK cells.	MAN1A1 RPS10 EIF4G1 DDX54 SDF4 EIF3A AGPS ANKLE2 BCR SLC4A2	5.10e-04	1168	84	10	19946888
Pubmed	Identification of novel candidate genes for treatment response to risperidone and susceptibility for schizophrenia: integrated analysis among pharmacogenomics, mouse expression, and genetic case-control association approaches.	BAG3 ATP2B2	5.15e-04	14	84	2	19850283
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	LMO7 G3BP2 EIF4G1 RBM6 EIF3A	5.44e-04	274	84	5	34244482
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	RBM15 LMO7 DHX40 KDM5C RBM6 BCR TEDC1	5.61e-04	588	84	7	38580884
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	RBM15 G3BP2 BAG3 RPS10 EIF4G1 DDX54 EIF3A USP39 EXOSC2	5.62e-04	971	84	9	33306668
Pubmed	RNA Directed Modulation of Phenotypic Plasticity in Human Cells.	RPS10 EIF3A	5.93e-04	15	84	2	27082860
Pubmed	Structural characterization of the human eukaryotic initiation factor 3 protein complex by mass spectrometry.	EIF4G1 EIF3A	5.93e-04	15	84	2	17322308
Pubmed	Multiple roles for Pax2 in the embryonic mouse eye.	VAX2 RAX	5.93e-04	15	84	2	33428890
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	RBM15 CSNK1E G3BP2 RPS10 EIF4G1 DDX54 EIF3A USP39 AGPS RRP1 NCOA5	6.28e-04	1425	84	11	30948266
Pubmed	Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.	FBXW8 G3BP2 EIF3A CLIC6 SAPCD2 RRP1	6.37e-04	432	84	6	7671812
Pubmed	Spatial and temporal regulation of Wnt/beta-catenin signaling is essential for development of the retinal pigment epithelium.	VAX2 RAX	6.77e-04	16	84	2	19596317
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	BHLHE23 LMO7 G3BP2 EIF4G1 DDX54 COQ8B SDF4 EIF3A USP39 EXOSC2 RRP1	6.85e-04	1440	84	11	30833792
Pubmed	Targeted and Interactome Proteomics Revealed the Role of PHD2 in Regulating BRD4 Proline Hydroxylation.	RBM15 RPS10 EIF4G1 EIF3A USP39 HDGFL2	7.09e-04	441	84	6	31239290
Pubmed	A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.	G3BP2 COQ8B NINL AGPS EXOSC2	7.93e-04	298	84	5	32353859
Pubmed	ALS/FTD-causing mutation in cyclin F causes the dysregulation of SFPQ.	RABEP2 RBM15 LMO7 CSNK1E DDX54 DIDO1 RRP1	7.95e-04	624	84	7	33729478
Interaction	TMSB4Y interactions	RRP36 DIDO1 RP9 RRP1 NCOA5	4.79e-07	39	81	5	int:TMSB4Y
Interaction	GAGE5 interactions	RRP36 RBM6 DIDO1 RP9 RRP1	2.07e-06	52	81	5	int:GAGE5
Interaction	SRP19 interactions	RRP36 G3BP2 BAG3 RPS10 EIF4G1 DDX54 EIF3A RRP1	6.18e-06	244	81	8	int:SRP19
Interaction	IFI27L1 interactions	RRP36 DIDO1 RP9 RRP1 NCOA5	6.33e-06	65	81	5	int:IFI27L1
Interaction	DRG1 interactions	G3BP2 RPS10 EIF4G1 DDX54 EIF3A DCAF11 LYL1 EXOSC2 RRP1	2.55e-05	388	81	9	int:DRG1
Interaction	LINC02910 interactions	RRP36 DIDO1 RP9 RRP1 NCOA5	4.04e-05	95	81	5	int:LINC02910
GeneFamily	PHD finger proteins	BAZ2A KDM5C PHF24 DIDO1 KDM2A FBXL19	2.74e-07	90	54	6	88
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	ARVCF PKP3 APC2	2.86e-04	43	54	3	409
GeneFamily	Zinc fingers CXXC-type	KDM2A FBXL19	5.67e-04	12	54	2	136
GeneFamily	F-box and leucine rich repeat proteins	KDM2A FBXL19	1.77e-03	21	54	2	558
GeneFamily	PHD finger proteins\|Lysine demethylases	KDM5C KDM2A	2.32e-03	24	54	2	485
GeneFamily	Basic helix-loop-helix proteins	BHLHE23 LYL1 NEUROD6	4.34e-03	110	54	3	420
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAN1A1 NFE2 DCAF11 LYL1 TFR2	2.64e-05	185	84	5	c4bf3ac684c1a8876b51f7af4d3a62dc47e961ee
ToppCell	BAL-Mild-cDC_12\|Mild / Compartment, Disease Groups and Clusters	RRP36 COQ8B HDGFL2 HACD1 MINDY1	2.64e-05	185	84	5	e867ed55ab0df018f14bca824da09d36d83e12f9
ToppCell	Immune-enucleated_erythrocyte\|World / Lineage, Cell type, age group and donor	MAN1A1 NFE2 DCAF11 LYL1 TFR2	2.71e-05	186	84	5	f9d5ec5cc8fd6e63bf25abe390307ec8a4a2d5a3
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma\|TCGA-Prostate / Sample_Type by Project: Shred V9	RABEP2 PHLDB3 ARVCF PKP3 SAPCD2	2.78e-05	187	84	5	fa0452f3382c22c0391b241d06504fda3c6a19f0
ToppCell	TCGA-Prostate-Primary_Tumor\|TCGA-Prostate / Sample_Type by Project: Shred V9	RABEP2 PHLDB3 ARVCF PKP3 SAPCD2	2.78e-05	187	84	5	3e6a95c912dad5d61e10497ffaafd2b9027cd13a
ToppCell	Fetal_29-31_weeks-Immune-enucleated_erythrocyte\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAN1A1 NFE2 DCAF11 LYL1 TFR2	2.93e-05	189	84	5	1900e574870fc647bfa11c732a72f3d38aab717c
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LMO7 PKP3 CLIC6 MARVELD3 SAPCD2	3.32e-05	194	84	5	20f81f457ab0a404600effe8beb91fe73d1cfc10
ToppCell	droplet-Marrow-BM-1m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL7C ANKRD11 LRRC58 RNF126 RRP1	3.40e-05	195	84	5	637b06ef3967b03f7165d102d316e8b7161a817d
ToppCell	mLN-(5)_Dendritic_cell-(54)_pDC\|mLN / shred on region, Cell_type, and subtype	KCNG2 IQSEC3 MAN1A1 NKD2 BAHCC1	3.74e-05	199	84	5	1e738219784a446ee8b0ddeb408e0050e1929e60
ToppCell	mLN-Dendritic_cell-pDC\|mLN / Region, Cell class and subclass	KCNG2 IQSEC3 MAN1A1 NKD2 BAHCC1	3.74e-05	199	84	5	54f1abb57af7bf8a8b82a38b933f257df3b5d8df
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ATXN7 MARVELD3 ANKLE2 RNF126 RRP1	3.83e-05	200	84	5	691b3edf7d8449556e8bf611662eb85772959f0f
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW08-Stem_cells-Stem_cells\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ATXN7 MARVELD3 ANKLE2 RNF126 RRP1	3.83e-05	200	84	5	36a110aa91a791fdf1142e7869e8aa0d342402d0
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells-Neuroepithelial_cell\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ATXN7 MARVELD3 ANKLE2 RNF126 RRP1	3.83e-05	200	84	5	4e077aa7faddcebdfc54667f8b3990704441005b
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW08-Stem_cells\|GW08 / Sample Type, Dataset, Time_group, and Cell type.	ATXN7 MARVELD3 ANKLE2 RNF126 RRP1	3.83e-05	200	84	5	d17ba4239e1fd702a3d757687110f0f2c6f91ef7
Disease	gamma-glutamyltyrosine measurement	MARVELD3 TUSC1	2.50e-03	27	81	2	EFO_0021144
Disease	corpus callosum mid-anterior volume measurement	TTC39C TG	2.50e-03	27	81	2	EFO_0010297
Disease	corpus callosum volume measurement	TTC39C RBM6 TG	2.66e-03	100	81	3	EFO_0010299

Protein segments in the cluster

Peptide	Gene	Start	Entry
AAGAAEDDPLRRTGR	SLC4A2	666	P04920
GAREERSREEGEQGP	BAHCC1	1211	Q9P281
SDPERGFERVGRELA	ANKLE2	556	Q86XL3
DLGGFDEDAEPRRSR	SDF4	86	Q9BRK5
PRDRRKDRGAADAGR	ANKRD11	1181	Q6UB99
SDGAEARRRLRECEG	ARVCF	531	O00192
ARRPGAAASGERDDR	BCR	131	P11274
PGRRGRRDGEVDATA	BAZ2A	1066	Q9UIF9
DEDDAFEQRRRRRGP	BHLHE23	71	Q8NDY6
RVNGRREDGEASEPR	CLIC6	431	Q96NY7
GAGEPRVFRPRDRDE	ATP2B2	641	Q01814
GFEVEEAGAARRRGR	ADAMTS17	106	Q8TE56
LSEDEAPGEARNGRR	FBXL19	341	Q6PCT2
GGPDRRLRVDFADTE	RBM15	516	Q96T37
PVAADDDERRRRPGA	RABEP2	6	Q9H5N1
DDERRRRPGAALEDS	RABEP2	11	Q9H5N1
GIPAGTAEEEEARRR	PALM2	56	Q8IXS6
RGELAGERVAARREE	PHLDB3	141	Q6NSJ2
EALRDEEERAGARPR	MAGEB4	306	O15481
EDDDEERAARRPGAG	MAPK8IP1	111	Q9UQF2
DSDEEGASDRRGPER	DDX54	781	Q8TDD1
AAERRARRPEVGSGR	FBXW8	31	Q8N3Y1
REEEAAEARAGPTER	KCNG2	126	Q9UJ96
RREPRDGRNGRDARD	NCOA5	36	Q9HCD5
PRRGAGLRRSEEEEE	DCAF11	21	Q8TEB1
RDADGEAREREPADQ	MINDY1	41	Q8N5J2
DREGTRAGEEERRQP	LMO7	1311	Q8WWI1
RSEREDAGEAARARG	GOLGA6L2	881	Q8N9W4
GRRGASLAREPEVEE	DPY19L2	21	Q6NUT2
PGGELRRRSAEDELA	EXOSC2	116	Q13868
RNLRGVDDGADIPRE	IQSEC3	811	Q9UPP2
SADDGERAANREGPR	NKD2	86	Q969F2
MSERAADDVRGEPRR	ATXN7	1	O15265
ADDVRGEPRRAAAAA	ATXN7	6	O15265
DLDRPGSDRQERERA	HDGFL2	646	Q7Z4V5
ELEARGEERRGAREA	LRRC58	31	Q96CX6
EERARRLRREPGGQD	PTPRU	631	Q92729
RLDERPAEGSRERGE	APC2	1656	O95996
GNGDEEAVDREPRRL	KDM2A	371	Q9Y2K7
EEERRRAGGGAERSR	BCL7C	56	Q8WUZ0
GPEEDRFSRRGADDD	EIF3A	971	Q14152
TADEDRGPRRGMDDD	EIF3A	1031	Q14152
RNADDDRGPRRGLDD	EIF3A	1061	Q14152
RGLDDDRGPRRGMDD	EIF3A	1071	Q14152
RGMDDDRGPRRGLDD	EIF3A	1101	Q14152
RNADDDRIPRRGAED	EIF3A	1121	Q14152
RADDDRFPRRGDDSR	EIF3A	1151	Q14152
AARERETRGGGDDRR	G3BP2	411	Q9UN86
GDDRRDIRRNDRGPG	G3BP2	421	Q9UN86
GEDREAPGERRRLGV	HACD1	56	B0YJ81
EEPDAQGRASEDRRR	DIDO1	2101	Q9BTC0
GRGLGEEDIRRAREA	COQ8B	51	Q96D53
RQEARRPEEGGARAA	C20orf144	101	Q9BQM9
DRGDRLERSERGGDR	EIF4G1	1156	Q04637
LERSERGGDRGDRLD	EIF4G1	1161	Q04637
SSDGNRRRDGDRDPE	MARVELD3	46	Q96A59
PDDGARRGSGRRAEA	LYL1	231	P12980
GARAEDAAEGRARRR	MAN1A1	91	P33908
DAAEGRARRREEGAP	MAN1A1	96	P33908
RARRREEGAPGDPEA	MAN1A1	101	P33908
AAQVEERRGRRGREE	CCDC177	396	Q9NQR7
AAARARDPAGERRAA	EME2	46	A4GXA9
RDPAGERRAAAEALR	EME2	51	A4GXA9
EGRADVRQARRDGVR	BAG3	471	O95817
DGAPAERRLGRADLV	BMP8B	91	P34820
AVAGRAPRRQEEGER	DHX40	6	Q8IX18
PTARGEAGSRDERRA	NFE2	216	Q16621
RGRDIHSGDFRDREG	RBM6	116	P78332
GREDVGAAGARRPRE	RP9	6	Q8TA86
ERDREREPEAASSRG	USP39	31	Q53GS9
QADDGRDPESRRERD	RNF126	101	Q9BV68
SRRRGVGADPEARAE	RRP1	391	P56182
GRESEEAAGAGPRRR	NINL	866	Q9Y2I6
RDVEAQRLVPDGDGR	PROB1	761	E7EW31
RLRDGRGVEPEEFDR	PHF24	81	Q9UPV7
FPAERGARGAKERDR	RAX	51	Q9Y2V3
SAADRDRDPDPDRAG	AGPS	21	O00116
DRDPDPDRAGRRLRV	AGPS	26	O00116
LQLDRRGAEGPEAER	PKP3	26	Q9Y446
RGAEGPEAERLRAAR	PKP3	31	Q9Y446
GERPARLTRGEADRD	RPS10	111	P46783
DARAREREAGRPGVL	TNRC18	396	O15417
GDGRGCEKAERRPER	PLEKHA6	211	Q9Y2H5
RALEADSGDARRAPR	SAPCD2	196	Q86UD0
DSGDARRAPRARGER	SAPCD2	201	Q86UD0
RRADGRGGRCAEAPD	SPRED3	306	Q2MJR0
HRLVRREDGAAGDRD	TEDC1	431	Q86SX3
ARRPRGARDREEDGG	RRP36	16	Q96EU6
AERDRGPARRAESGG	VAX2	6	Q9UIW0
GDRARGAREAGPDAR	TARBP1	246	Q13395
DGIRRGRPRADTVRD	ZNF367	141	Q7RTV3
QQRPRRRDDGDSDAA	TTC39C	6	Q8N584
REGDARTVPAARARE	TSPY26P	21	Q9H489
DPRRVSLAADRGGAD	TG	2376	P01266
MEREGEGASAPRDRR	TTC22	551	Q5TAA0
GRPEDLQDLRARGVD	TFR2	251	Q9UP52
EAAGRSEREQDGDPR	THEG	16	Q9P2T0
RTEARDQPEDGADGR	TNFRSF11A	486	Q9Y6Q6
RARDSGREDEPGSPR	TUSC1	141	Q2TAM9
GAARNPEDVDRERRE	CSNK1E	296	P49674
RKVDRGGEGDDPARE	KDM5C	1461	P41229
EEEDENGLPRRRGLR	NEUROD6	66	Q96NK8