Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionchannel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A SCN5A SCNN1G PKD1L2 HVCN1 AQP4 RYR1 RYR2 KCNH3 ITPR3

9.82e-175257221GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A SCN5A SCNN1G PKD1L2 HVCN1 AQP4 RYR1 RYR2 KCNH3 ITPR3

1.02e-165267221GO:0022803
GeneOntologyMolecularFunctionmonoatomic ion channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A SCN5A SCNN1G PKD1L2 HVCN1 RYR1 RYR2 KCNH3 ITPR3

1.17e-164597220GO:0005216
GeneOntologyMolecularFunctiontransporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9A9 ATG9B SLC9C1 CATSPER2 ABCA6 SLC38A9 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G ATP13A3 RFT1 PKD1L2 HVCN1 AQP4 RYR1 RYR2 KCNH3 ITPR3

1.71e-1512897228GO:0005215
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G ATP13A3 PKD1L2 HVCN1 RYR1 RYR2 KCNH3 ITPR3

2.69e-157937223GO:0015075
GeneOntologyMolecularFunctionmonoatomic cation channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 SCN3A SCN5A SCNN1G PKD1L2 HVCN1 RYR1 RYR2 KCNH3 ITPR3

3.83e-153437217GO:0005261
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 SCN3A ATP6V0A4 SCN5A SCNN1G ATP13A3 PKD1L2 HVCN1 RYR1 RYR2 KCNH3 ITPR3

1.05e-146647221GO:0008324
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G PKD1L2 HVCN1 AQP4 RYR1 RYR2 KCNH3 ITPR3

1.23e-147587222GO:0015318
GeneOntologyMolecularFunctiontransmembrane transporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9A9 SLC9C1 CATSPER2 ABCA6 SLC38A9 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G ATP13A3 PKD1L2 HVCN1 AQP4 RYR1 RYR2 KCNH3 ITPR3

1.75e-1411807226GO:0022857
GeneOntologyMolecularFunctioncalcium channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 PKD1L2 RYR1 RYR2 ITPR3

3.47e-141297212GO:0005262
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 SCN3A SCN5A SCNN1G PKD1L2 RYR1 RYR2 KCNH3 ITPR3

3.81e-144657218GO:0046873
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 SCN3A ATP6V0A4 SCN5A SCNN1G PKD1L2 HVCN1 RYR1 RYR2 KCNH3 ITPR3

4.37e-146277220GO:0022890
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 RYR1

6.08e-1446729GO:0005245
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 PKD1L2 RYR1 RYR2 ITPR3

2.34e-131517212GO:0015085
GeneOntologyMolecularFunctiongated channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 CFTR SCNN1G HVCN1 RYR1 RYR2 KCNH3 ITPR3

8.02e-133347215GO:0022836
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

5.21e-1214726GO:0008331
GeneOntologyMolecularFunctionvoltage-gated monoatomic cation channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 HVCN1 RYR1 KCNH3

7.00e-121527211GO:0022843
GeneOntologyMolecularFunctionvoltage-gated monoatomic ion channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 HVCN1 RYR1 KCNH3

4.97e-111827211GO:0005244
GeneOntologyMolecularFunctionvoltage-gated channel activity

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 HVCN1 RYR1 KCNH3

5.59e-111847211GO:0022832
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of cytosolic calcium levels

CACNA1A CACNA1B CACNA1D CACNA1E

1.93e-089724GO:0099511
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in regulation of presynaptic cytosolic calcium levels

CACNA1A CACNA1B CACNA1D CACNA1E

1.93e-089724GO:0099626
GeneOntologyMolecularFunctionG protein-coupled receptor activity

TAS2R1 OR4C3 OR6B3 CALCR OR6N2 OR6C1 ADGRE4P GPR141 GCGR PTAFR OR5AR1 OR6B2 CRHR1 CRHR2 OR52J3

4.75e-078847215GO:0004930
GeneOntologyMolecularFunctiontransmembrane signaling receptor activity

EPHB6 TAS2R1 OR4C3 OR6B3 CALCR OR6N2 OR6C1 ADGRE4P GPR141 GCGR ACVR1B PTAFR OR5AR1 OR6B2 CRHR1 CRHR2 OR52J3

4.63e-0613537217GO:0004888
GeneOntologyMolecularFunctionintracellularly ligand-gated monoatomic ion channel activity

CFTR RYR1 RYR2 ITPR3

5.87e-0633724GO:0005217
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

CATSPER2 CATSPER4 CFTR SCNN1G RYR1 RYR2 ITPR3

6.12e-06193727GO:0015276
GeneOntologyMolecularFunctionligand-gated channel activity

CATSPER2 CATSPER4 CFTR SCNN1G RYR1 RYR2 ITPR3

7.01e-06197727GO:0022834
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

CATSPER2 CATSPER4 SCNN1G RYR1 RYR2 ITPR3

1.14e-05140726GO:0099094
GeneOntologyMolecularFunctionintracellularly gated calcium channel activity

RYR1 RYR2 ITPR3

3.53e-0518723GO:0015278
GeneOntologyMolecularFunctioncorticotropin-releasing hormone receptor activity

CRHR1 CRHR2

3.84e-053722GO:0043404
GeneOntologyMolecularFunctioncorticotrophin-releasing factor receptor activity

CRHR1 CRHR2

3.84e-053722GO:0015056
GeneOntologyMolecularFunctionpeptide hormone binding

CALCR GCGR CRHR1 CRHR2

4.61e-0555724GO:0017046
GeneOntologyMolecularFunctionryanodine-sensitive calcium-release channel activity

RYR1 RYR2

7.66e-054722GO:0005219
GeneOntologyMolecularFunctionamide binding

CACNA1A CACNA1B CALCR GCGR CRHR1 CRHR2 RYR2

1.01e-04299727GO:0033218
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity involved in cardiac muscle cell action potential

CACNA1C CACNA1D

1.27e-045722GO:0086007
GeneOntologyMolecularFunctioncalmodulin binding

CACNA1A CACNA1C SCN3A SCN5A RYR1 RYR2

1.81e-04230726GO:0005516
GeneOntologyMolecularFunctionligand-gated calcium channel activity

RYR1 RYR2 ITPR3

1.88e-0431723GO:0099604
GeneOntologyMolecularFunctioncalcium-induced calcium release activity

RYR1 RYR2

1.91e-046722GO:0048763
GeneOntologyMolecularFunctionchloride channel inhibitor activity

CFTR VAMP8

2.66e-047722GO:0019869
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

SLC9A9 SLC9C1 SCN3A SCN5A SCNN1G

3.82e-04171725GO:0015081
GeneOntologyMolecularFunctionhormone binding

CALCR GCGR CRHR1 CRHR2

5.25e-04103724GO:0042562
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA6 CFTR ATP6V0A4 ATP13A3

6.50e-04109724GO:0042626
GeneOntologyMolecularFunctionABC-type transporter activity

ABCA6 CFTR ATP13A3

7.35e-0449723GO:0140359
GeneOntologyMolecularFunctionsodium channel activity

SCN3A SCN5A SCNN1G

8.75e-0452723GO:0005272
GeneOntologyMolecularFunctionolfactory receptor activity

OR4C3 OR6B3 OR6N2 OR6C1 OR5AR1 OR6B2 OR52J3

9.15e-04431727GO:0004984
GeneOntologyMolecularFunctionpotassium:proton antiporter activity

SLC9A9 SLC9C1

1.13e-0314722GO:0015386
GeneOntologyMolecularFunctionodorant binding

OR6B3 OR6N2 OR5AR1 OR6B2

1.15e-03127724GO:0005549
GeneOntologyMolecularFunctionchloride channel regulator activity

CFTR VAMP8

1.31e-0315722GO:0017081
GeneOntologyMolecularFunctionG protein-coupled peptide receptor activity

CALCR GCGR CRHR1 CRHR2

1.36e-03133724GO:0008528
GeneOntologyMolecularFunctionsodium:proton antiporter activity

SLC9A9 SLC9C1

1.49e-0316722GO:0015385
GeneOntologyMolecularFunctionpeptide receptor activity

CALCR GCGR CRHR1 CRHR2

1.65e-03140724GO:0001653
GeneOntologyMolecularFunctionsolute:potassium antiporter activity

SLC9A9 SLC9C1

2.11e-0319722GO:0022821
GeneOntologyMolecularFunctionankyrin binding

CACNA1D SCN5A

3.09e-0323722GO:0030506
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA6 CFTR ATP6V0A4 ATP13A3

3.92e-03178724GO:0015399
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN3A SCN5A

3.94e-0326722GO:0005248
GeneOntologyMolecularFunctionmetal cation:proton antiporter activity

SLC9A9 SLC9C1

4.25e-0327722GO:0051139
GeneOntologyMolecularFunctioncalcium-activated cation channel activity

CATSPER2 CATSPER4

4.25e-0327722GO:0005227
GeneOntologyMolecularFunctionscaffold protein binding

SCN5A CD163 RYR2

4.62e-0393723GO:0097110
GeneOntologyMolecularFunctionproton transmembrane transporter activity

SLC9A9 SLC9C1 ATP6V0A4 HVCN1

4.76e-03188724GO:0015078
GeneOntologyMolecularFunctioncalcium ion binding

CACNA1B CACNA1E FAT3 ADGRE4P PKD1L2 RYR1 RYR2 ITPR3

5.44e-03749728GO:0005509
GeneOntologyMolecularFunctionalpha-actinin binding

CACNA1C CACNA1D

5.57e-0331722GO:0051393
GeneOntologyMolecularFunctionmonoatomic ion-gated channel activity

CATSPER2 CATSPER4

5.57e-0331722GO:0022839
GeneOntologyMolecularFunctionamyloid-beta binding

CACNA1A CACNA1B CALCR

5.98e-03102723GO:0001540
GeneOntologyMolecularFunctionactive transmembrane transporter activity

SLC9A9 SLC9C1 ABCA6 CFTR ATP6V0A4 ATP13A3

7.45e-03477726GO:0022804
GeneOntologyMolecularFunctionP-type transmembrane transporter activity

ATP6V0A4 ATP13A3

7.46e-0336722GO:0140358
GeneOntologyMolecularFunctionP-type ion transporter activity

ATP6V0A4 ATP13A3

7.46e-0336722GO:0015662
GeneOntologyMolecularFunctionguanyl-nucleotide exchange factor activity

KALRN SLC38A9 IQSEC2 GCGR

9.72e-03231724GO:0005085
GeneOntologyMolecularFunctionprotein phosphatase 2A binding

CACNA1B CACNA1C

1.01e-0242722GO:0051721
GeneOntologyMolecularFunctionmetal cation:monoatomic cation antiporter activity

SLC9A9 SLC9C1

1.05e-0243722GO:0140828
GeneOntologyMolecularFunctionactinin binding

CACNA1C CACNA1D

1.05e-0243722GO:0042805
GeneOntologyMolecularFunctionG-protein alpha-subunit binding

PKD1L2 CRHR1

1.05e-0243722GO:0001965
GeneOntologyMolecularFunctionion channel inhibitor activity

CFTR VAMP8

1.30e-0248722GO:0008200
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G ATP13A3 PKD1L2 HVCN1 CRHR1 RYR1 RYR2 KCNH3 ITPR3

5.26e-149427223GO:0098655
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G ATP13A3 PKD1L2 HVCN1 CRHR1 RYR1 RYR2 KCNH3 ITPR3

2.00e-1311157224GO:0034220
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G PKD1L2 HVCN1 CRHR1 RYR1 RYR2 KCNH3 ITPR3

3.38e-139227222GO:0098662
GeneOntologyBiologicalProcessmonoatomic cation transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G ATP13A3 PKD1L2 HVCN1 CRHR1 CRHR2 RYR1 RYR2 KCNH3 ITPR3

4.43e-1311577224GO:0006812
GeneOntologyBiologicalProcessmonoatomic ion transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G ATP13A3 PKD1L2 HVCN1 CRHR1 CRHR2 RYR1 RYR2 KCNH3 ITPR3

2.28e-1213747225GO:0006811
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G PKD1L2 HVCN1 CRHR1 RYR1 RYR2 KCNH3 ITPR3

2.38e-1210177222GO:0098660
GeneOntologyBiologicalProcessmetal ion transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CATSPER2 CATSPER4 CFTR SCN3A SCN5A SCNN1G PKD1L2 CRHR1 CRHR2 RYR1 RYR2 KCNH3 ITPR3

1.48e-1110007221GO:0030001
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 SCN5A SCNN1G

6.47e-111427210GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 SCN5A SCNN1G

6.47e-111427210GO:0098659
GeneOntologyBiologicalProcessintracellular chemical homeostasis

CACNA1A CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CFTR ATP6V0A4 CD40 SCNN1G ATP13A3 GRINA HVCN1 AQP4 CRHR2 RYR1 RYR2 ITPR3

8.16e-118667219GO:0055082
GeneOntologyBiologicalProcesscellular homeostasis

CACNA1A CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CFTR ATP6V0A4 CD40 SCNN1G ATP13A3 GRINA HVCN1 AQP4 CRHR2 RYR1 RYR2 ITPR3

6.67e-109817219GO:0019725
GeneOntologyBiologicalProcesscalcium ion transmembrane transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 PKD1L2 CRHR1 RYR1 RYR2 ITPR3

8.91e-103927213GO:0070588
GeneOntologyBiologicalProcesscalcium ion transport

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 PKD1L2 CRHR1 CRHR2 RYR1 RYR2 ITPR3

2.10e-095097214GO:0006816
GeneOntologyBiologicalProcessintracellular monoatomic cation homeostasis

CACNA1A CACNA1C CACNA1F SLC9A9 SLC9C1 CFTR ATP6V0A4 CD40 SCNN1G ATP13A3 GRINA HVCN1 RYR1 RYR2 ITPR3

2.43e-096117215GO:0030003
GeneOntologyBiologicalProcessintracellular monoatomic ion homeostasis

CACNA1A CACNA1C CACNA1F SLC9A9 SLC9C1 CFTR ATP6V0A4 CD40 SCNN1G ATP13A3 GRINA HVCN1 RYR1 RYR2 ITPR3

3.09e-096227215GO:0006873
GeneOntologyBiologicalProcesschemical homeostasis

CACNA1A CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 CFTR ATP6V0A4 CD40 SCNN1G GCGR ATP13A3 GRINA HVCN1 AQP4 CRHR2 RYR1 RYR2 ITPR3

5.72e-0912497220GO:0048878
GeneOntologyBiologicalProcessimport across plasma membrane

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 SLC9C1 SCN5A SCNN1G

7.16e-092307210GO:0098739
GeneOntologyBiologicalProcesscalcium ion import across plasma membrane

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

1.60e-0848726GO:0098703
GeneOntologyBiologicalProcesscalcium ion import into cytosol

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

1.60e-0848726GO:1902656
GeneOntologyBiologicalProcessmonoatomic cation homeostasis

CACNA1A CACNA1C CACNA1F SLC9A9 SLC9C1 CFTR ATP6V0A4 CD40 SCNN1G ATP13A3 GRINA HVCN1 RYR1 RYR2 ITPR3

1.66e-087057215GO:0055080
GeneOntologyBiologicalProcessmonoatomic ion homeostasis

CACNA1A CACNA1C CACNA1F SLC9A9 SLC9C1 CFTR ATP6V0A4 CD40 SCNN1G ATP13A3 GRINA HVCN1 RYR1 RYR2 ITPR3

2.07e-087177215GO:0050801
GeneOntologyBiologicalProcesscalcium ion import

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CRHR2

5.04e-0898727GO:0070509
GeneOntologyBiologicalProcesscalcium ion transmembrane import into cytosol

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

6.41e-08217729GO:0097553
GeneOntologyBiologicalProcesssensory perception

CACNA1D CACNA1E CACNA1F TAS2R1 OR4C3 OR6B3 OR6N2 OR6C1 ATP6V0A4 SCNN1G OR5AR1 OR6B2 AQP4 RTP4 ITPR3 OR52J3

6.66e-0710727216GO:0007600
GeneOntologyBiologicalProcessresponse to pain

CACNA1A CACNA1B CACNA1E SCN3A CRHR1

9.33e-0751725GO:0048265
GeneOntologyBiologicalProcessparturition

CYP1A1 KALRN PTAFR CRHR1

9.52e-0722724GO:0007567
GeneOntologyBiologicalProcessdetection of stimulus

CACNA1F TAS2R1 OR4C3 OR6B3 OR6N2 OR6C1 CRTAM PKD1L2 OR5AR1 OR6B2 RTP4 RYR2 OR52J3

1.12e-067227213GO:0051606
GeneOntologyBiologicalProcesssodium ion import across plasma membrane

SLC9A9 SLC9C1 SCN5A SCNN1G

2.25e-0627724GO:0098719
GeneOntologyBiologicalProcessmaternal process involved in parturition

CYP1A1 KALRN PTAFR

2.26e-068723GO:0060137
GeneOntologyBiologicalProcessblood circulation

CACNA1B CACNA1C CACNA1D CACNA1E CFTR SCN3A SCN5A SCNN1G GCGR PTAFR CRHR2 RYR2

2.29e-066487212GO:0008015
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

CACNA1C CACNA1D SCN3A SCN5A RYR2

2.50e-0662725GO:0086002
GeneOntologyBiologicalProcesssensory perception of chemical stimulus

TAS2R1 OR4C3 OR6B3 OR6N2 OR6C1 SCNN1G OR5AR1 OR6B2 RTP4 ITPR3 OR52J3

2.89e-065477211GO:0007606
GeneOntologyBiologicalProcessmembrane depolarization

CACNA1A CACNA1C CACNA1D CFTR SCN3A SCN5A

4.10e-06121726GO:0051899
GeneOntologyBiologicalProcessintracellular calcium ion homeostasis

CACNA1A CACNA1C CACNA1F CD40 ATP13A3 GRINA RYR1 RYR2 ITPR3

4.30e-06359729GO:0006874
GeneOntologyBiologicalProcessG protein-coupled receptor signaling pathway

CACNA1D TAS2R1 OR4C3 OR6B3 CALCR OR6N2 OR6C1 ADGRE4P GPR141 GCGR PTAFR OR5AR1 OR6B2 CRHR1 CRHR2 ITPR3 OR52J3

4.52e-0613957217GO:0007186
GeneOntologyBiologicalProcessbehavioral response to pain

CACNA1A CACNA1E SCN3A CRHR1

4.56e-0632724GO:0048266
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

CACNA1D SCN5A RYR2

4.81e-0610723GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

CACNA1D SCN5A RYR2

4.81e-0610723GO:0086015
GeneOntologyBiologicalProcesscell-cell signaling involved in cardiac conduction

CACNA1C CACNA1D SCN5A RYR2

5.85e-0634724GO:0086019
GeneOntologyBiologicalProcessregulation of heart rate

CACNA1C CACNA1D CACNA1E SCN5A CRHR2 RYR2

5.93e-06129726GO:0002027
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell communication

CACNA1D SCN5A RYR2

6.60e-0611723GO:0086070
GeneOntologyBiologicalProcessmembrane depolarization during action potential

CACNA1C CACNA1D SCN3A SCN5A

7.39e-0636724GO:0086010
GeneOntologyBiologicalProcesscirculatory system process

CACNA1B CACNA1C CACNA1D CACNA1E CFTR SCN3A SCN5A SCNN1G GCGR PTAFR CRHR2 RYR2

8.05e-067337212GO:0003013
GeneOntologyBiologicalProcesscalcium ion homeostasis

CACNA1A CACNA1C CACNA1F CD40 ATP13A3 GRINA RYR1 RYR2 ITPR3

8.21e-06389729GO:0055074
GeneOntologyBiologicalProcessAV node cell to bundle of His cell signaling

CACNA1C SCN5A RYR2

8.77e-0612723GO:0086027
GeneOntologyBiologicalProcessAV node cell action potential

CACNA1C SCN5A RYR2

8.77e-0612723GO:0086016
GeneOntologyBiologicalProcessheart contraction

CACNA1B CACNA1C CACNA1D CACNA1E SCN3A SCN5A CRHR2 RYR2

9.28e-06298728GO:0060047
GeneOntologyBiologicalProcesspositive regulation of adenylate cyclase activity

CACNA1C CACNA1D CALCR CRHR1

1.13e-0540724GO:0045762
GeneOntologyBiologicalProcessheart process

CACNA1B CACNA1C CACNA1D CACNA1E SCN3A SCN5A CRHR2 RYR2

1.21e-05309728GO:0003015
GeneOntologyBiologicalProcesscardiac muscle cell action potential

CACNA1C CACNA1D SCN3A SCN5A RYR2

1.33e-0587725GO:0086001
GeneOntologyBiologicalProcessdetection of chemical stimulus

TAS2R1 OR4C3 OR6B3 OR6N2 OR6C1 OR5AR1 OR6B2 RTP4 RYR2 OR52J3

1.34e-055247210GO:0009593
GeneOntologyBiologicalProcessAV node cell to bundle of His cell communication

CACNA1C SCN5A RYR2

1.80e-0515723GO:0086067
GeneOntologyBiologicalProcesscardiac muscle cell contraction

CACNA1C CACNA1D SCN3A SCN5A RYR2

1.84e-0593725GO:0086003
GeneOntologyBiologicalProcessregulation of intracellular pH

SLC9A9 SLC9C1 CFTR ATP6V0A4 HVCN1

1.94e-0594725GO:0051453
GeneOntologyBiologicalProcessexocytosis

CACNA1A CACNA1B CACNA1C CACNA1E CFTR GCGR PTAFR VAMP8 CRHR1

1.96e-05434729GO:0006887
GeneOntologyBiologicalProcessglucose homeostasis

CACNA1A CACNA1C CACNA1D CACNA1E CFTR GCGR AQP4 CRHR2

2.30e-05338728GO:0042593
GeneOntologyBiologicalProcesscarbohydrate homeostasis

CACNA1A CACNA1C CACNA1D CACNA1E CFTR GCGR AQP4 CRHR2

2.35e-05339728GO:0033500
GeneOntologyBiologicalProcessregulation of hormone levels

CACNA1A CYP1A1 CACNA1C CACNA1D CACNA1E KALRN DHCR7 CFTR VAMP8 CRHR1 CRHR2

2.36e-056847211GO:0010817
GeneOntologyBiologicalProcesspositive regulation of cyclase activity

CACNA1C CACNA1D CALCR CRHR1

2.36e-0548724GO:0031281
GeneOntologyBiologicalProcesspositive regulation of lyase activity

CACNA1C CACNA1D CALCR CRHR1

2.57e-0549724GO:0051349
GeneOntologyBiologicalProcessregulation of heart contraction

CACNA1B CACNA1C CACNA1D CACNA1E SCN5A CRHR2 RYR2

2.59e-05249727GO:0008016
GeneOntologyBiologicalProcessregulation of cellular pH

SLC9A9 SLC9C1 CFTR ATP6V0A4 HVCN1

2.75e-05101725GO:0030641
GeneOntologyBiologicalProcessregulation of hormone secretion

CACNA1C CACNA1D CACNA1E KALRN CFTR VAMP8 CRHR1 CRHR2

3.26e-05355728GO:0046883
GeneOntologyBiologicalProcessdetection of stimulus involved in sensory perception

CACNA1F TAS2R1 OR4C3 OR6B3 OR6N2 OR6C1 OR5AR1 OR6B2 RTP4 OR52J3

3.29e-055827210GO:0050906
GeneOntologyBiologicalProcessmembrane depolarization during atrial cardiac muscle cell action potential

CACNA1C SCN5A

3.60e-053722GO:0098912
GeneOntologyBiologicalProcessatrial cardiac muscle cell to AV node cell communication

CACNA1C SCN5A RYR2

3.80e-0519723GO:0086066
GeneOntologyBiologicalProcessatrial cardiac muscle cell to AV node cell signaling

CACNA1C SCN5A RYR2

3.80e-0519723GO:0086026
GeneOntologyBiologicalProcessatrial cardiac muscle cell action potential

CACNA1C SCN5A RYR2

3.80e-0519723GO:0086014
GeneOntologyBiologicalProcessdetection of chemical stimulus involved in sensory perception

TAS2R1 OR4C3 OR6B3 OR6N2 OR6C1 OR5AR1 OR6B2 RTP4 OR52J3

4.67e-05485729GO:0050907
GeneOntologyBiologicalProcessregulation of secretion by cell

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E KALRN CFTR PTAFR VAMP8 CRHR1 CRHR2

4.84e-057407211GO:1903530
GeneOntologyBiologicalProcesssodium ion transport

SLC9A9 SLC9C1 CATSPER4 CFTR SCN3A SCN5A SCNN1G

4.88e-05275727GO:0006814
GeneOntologyBiologicalProcessregulation of adenylate cyclase activity

CACNA1C CACNA1D CALCR CRHR1

5.37e-0559724GO:0045761
GeneOntologyBiologicalProcesscell communication involved in cardiac conduction

CACNA1C CACNA1D SCN5A RYR2

5.37e-0559724GO:0086065
GeneOntologyBiologicalProcessinorganic ion homeostasis

CACNA1A CACNA1C CACNA1F CD40 SCNN1G ATP13A3 GRINA RYR1 RYR2 ITPR3

5.76e-056227210GO:0098771
GeneOntologyBiologicalProcessresponse to organic cyclic compound

CACNA1B CYP1A1 CACNA1C CALCR CFTR SCN5A CD40 SCNN1G PTAFR CRHR1 RYR1 RYR2 ITPR3

6.06e-0510487213GO:0014070
GeneOntologyBiologicalProcessregulation of membrane depolarization

CACNA1C CACNA1D CFTR SCN5A

6.13e-0561724GO:0003254
GeneOntologyBiologicalProcessregulation of pH

SLC9A9 SLC9C1 CFTR ATP6V0A4 HVCN1

6.28e-05120725GO:0006885
GeneOntologyBiologicalProcessmembrane depolarization during cardiac muscle cell action potential

CACNA1C CACNA1D SCN5A

6.87e-0523723GO:0086012
GeneOntologyBiologicalProcessregulated exocytosis

CACNA1A CACNA1B CACNA1C CACNA1E PTAFR VAMP8 CRHR1

6.97e-05291727GO:0045055
GeneOntologyBiologicalProcessmulticellular organismal response to stress

CACNA1A CACNA1B CACNA1E SCN3A CRHR1

7.92e-05126725GO:0033555
GeneOntologyBiologicalProcesspositive regulation of secretion by cell

CACNA1B CACNA1C CACNA1D CFTR PTAFR VAMP8 CRHR1 CRHR2

8.10e-05404728GO:1903532
GeneOntologyBiologicalProcessactin-mediated cell contraction

CACNA1C CACNA1D SCN3A SCN5A RYR2

8.22e-05127725GO:0070252
GeneOntologyBiologicalProcesssignal release

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E KALRN CFTR VAMP8 CRHR1 CRHR2

8.63e-056537210GO:0023061
GeneOntologyBiologicalProcesssodium ion transmembrane transport

SLC9A9 SLC9C1 CFTR SCN3A SCN5A SCNN1G

8.79e-05208726GO:0035725
GeneOntologyBiologicalProcessregulation of secretion

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E KALRN CFTR PTAFR VAMP8 CRHR1 CRHR2

9.83e-058017211GO:0051046
GeneOntologyBiologicalProcessregulation of cyclase activity

CACNA1C CACNA1D CALCR CRHR1

9.94e-0569724GO:0031279
GeneOntologyBiologicalProcesssensory perception of taste

TAS2R1 SCNN1G RTP4 ITPR3

1.05e-0470724GO:0050909
GeneOntologyBiologicalProcesshormone secretion

CACNA1C CACNA1D CACNA1E KALRN CFTR VAMP8 CRHR1 CRHR2

1.06e-04420728GO:0046879
GeneOntologyBiologicalProcessstriated muscle contraction

CACNA1C CACNA1D SCN3A SCN5A RYR1 RYR2

1.11e-04217726GO:0006941
GeneOntologyBiologicalProcessmembrane depolarization during SA node cell action potential

CACNA1D SCN5A

1.19e-045722GO:0086046
GeneOntologyBiologicalProcesspositive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel

CACNA1C CACNA1D

1.19e-045722GO:1904879
GeneOntologyBiologicalProcessregulation of lyase activity

CACNA1C CACNA1D CALCR CRHR1

1.24e-0473724GO:0051339
GeneOntologyBiologicalProcesshormone transport

CACNA1C CACNA1D CACNA1E KALRN CFTR VAMP8 CRHR1 CRHR2

1.29e-04432728GO:0009914
GeneOntologyBiologicalProcesspositive regulation of cytosolic calcium ion concentration

CACNA1A CACNA1C CALCR CRHR1 RYR2 ITPR3

1.32e-04224726GO:0007204
GeneOntologyBiologicalProcessregulation of calcium ion transport

CACNA1B CACNA1C CACNA1D CACNA1F CRHR1 CRHR2 RYR2

1.33e-04323727GO:0051924
GeneOntologyBiologicalProcesspositive regulation of secretion

CACNA1B CACNA1C CACNA1D CFTR PTAFR VAMP8 CRHR1 CRHR2

1.35e-04435728GO:0051047
GeneOntologyBiologicalProcessregulation of blood circulation

CACNA1B CACNA1C CACNA1D CACNA1E SCN5A CRHR2 RYR2

1.41e-04326727GO:1903522
GeneOntologyBiologicalProcessorganic cation transport

CACNA1A SLC38A9 ATP13A3 CRHR1 CRHR2

1.54e-04145725GO:0015695
GeneOntologyBiologicalProcessregulation of exocytosis

CACNA1A CACNA1E CFTR PTAFR VAMP8 CRHR1

1.63e-04233726GO:0017157
GeneOntologyBiologicalProcesspeptide hormone secretion

CACNA1C CACNA1D CACNA1E KALRN CFTR CRHR1 CRHR2

1.64e-04334727GO:0030072
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 RYR1

4.04e-1446729GO:0005891
GeneOntologyCellularComponentcalcium channel complex

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 RYR1 RYR2

6.41e-14737210GO:0034704
GeneOntologyCellularComponentmonoatomic ion channel complex

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 CFTR SCN3A SCN5A SCNN1G HVCN1 RYR1 RYR2 KCNH3

1.56e-133787216GO:0034702
GeneOntologyCellularComponentcation channel complex

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 SCN3A SCN5A SCNN1G RYR1 RYR2

1.30e-122357213GO:0034703
GeneOntologyCellularComponenttransmembrane transporter complex

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G HVCN1 RYR1 RYR2 KCNH3

1.73e-125237217GO:1902495
GeneOntologyCellularComponenttransporter complex

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G HVCN1 RYR1 RYR2 KCNH3

3.86e-125507217GO:1990351
GeneOntologyCellularComponentmembrane protein complex

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CALCR CATSPER2 SLC38A9 CATSPER4 CFTR SCN3A ATP6V0A4 SCN5A CD40 SCNN1G ACVR1B VAMP8 HVCN1 RYR1 RYR2 KCNH3

3.10e-0914987222GO:0098796
GeneOntologyCellularComponentplasma membrane protein complex

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CALCR CATSPER2 CATSPER4 SCN3A SCN5A CD40 ACVR1B RYR1

3.91e-077857214GO:0098797
GeneOntologyCellularComponentneuronal cell body

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CALCR KALRN CFTR SCN3A CD40 CRHR1 CRHR2 ITPR3

8.18e-078357214GO:0043025
GeneOntologyCellularComponentcell body

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CALCR KALRN CFTR SCN3A CD40 CRHR1 CRHR2 ITPR3

2.87e-069297214GO:0044297
GeneOntologyCellularComponentsomatodendritic compartment

EPHB6 CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CALCR KALRN FAT3 CFTR SCN3A CD40 CRHR1 CRHR2 ITPR3

3.30e-0612287216GO:0036477
GeneOntologyCellularComponentsarcolemma

CACNA1C CACNA1D COL6A3 SCN5A AQP4 RYR1 RYR2

4.10e-06190727GO:0042383
GeneOntologyCellularComponentT-tubule

CACNA1C CACNA1D SCN5A AQP4 RYR1

7.78e-0679725GO:0030315
GeneOntologyCellularComponentrecycling endosome membrane

SLC9A9 ATG9B CFTR ATP13A3 VAMP8

4.24e-05112725GO:0055038
GeneOntologyCellularComponentendocytic vesicle membrane

SLC9A9 CFTR ATP6V0A4 VAMP8 HVCN1 CD163

9.07e-05212726GO:0030666
GeneOntologyCellularComponentcell surface

EPHB6 CACNA1C CACNA1D CFTR SCN5A CD40 ADGRE4P SCNN1G ADAM30 ACVR1B VAMP8 AQP4 CD163

9.56e-0511117213GO:0009986
GeneOntologyCellularComponentperikaryon

CACNA1A CACNA1C CACNA1D CACNA1E CACNA1F CRHR2

1.20e-04223726GO:0043204
GeneOntologyCellularComponentcytoplasmic vesicle membrane

SLC9A9 ATG9B SPACA1 SLC38A9 CFTR ATP6V0A4 ADAM30 ATP13A3 PTAFR VAMP8 HVCN1 AQP4 CD163 ITPR3

1.27e-0413077214GO:0030659
GeneOntologyCellularComponentsodium channel complex

SCN3A SCN5A SCNN1G

1.34e-0429723GO:0034706
GeneOntologyCellularComponentvesicle membrane

SLC9A9 ATG9B SPACA1 SLC38A9 CFTR ATP6V0A4 ADAM30 ATP13A3 PTAFR VAMP8 HVCN1 AQP4 CD163 ITPR3

1.47e-0413257214GO:0012506
GeneOntologyCellularComponentZ disc

CACNA1C CACNA1D SCN5A RYR1 RYR2

1.74e-04151725GO:0030018
GeneOntologyCellularComponentphagocytic vesicle membrane

SLC9A9 ATP6V0A4 VAMP8 HVCN1

1.94e-0483724GO:0030670
GeneOntologyCellularComponentpresynapse

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E KALRN WDR7 IQSEC2 ATP6V0A4 CRHR2 ITPR3

2.11e-048867211GO:0098793
GeneOntologyCellularComponentendosome membrane

SLC9A9 ATG9B SLC38A9 CFTR ATP6V0A4 ADAM30 ATP13A3 VAMP8 AQP4

2.17e-04602729GO:0010008
GeneOntologyCellularComponentI band

CACNA1C CACNA1D SCN5A RYR1 RYR2

2.71e-04166725GO:0031674
GeneOntologyCellularComponentlate endosome membrane

SLC9A9 SLC38A9 ADAM30 ATP13A3 VAMP8

3.83e-04179725GO:0031902
GeneOntologyCellularComponentjunctional sarcoplasmic reticulum membrane

RYR1 RYR2

5.17e-0410722GO:0014701
GeneOntologyCellularComponentsarcoplasm

SCN3A RYR1 RYR2 ITPR3

6.49e-04114724GO:0016528
GeneOntologyCellularComponentdendrite

EPHB6 CACNA1A CACNA1B CACNA1C CACNA1D FAT3 CFTR CRHR1 CRHR2 ITPR3

6.88e-048587210GO:0030425
GeneOntologyCellularComponentdendritic tree

EPHB6 CACNA1A CACNA1B CACNA1C CACNA1D FAT3 CFTR CRHR1 CRHR2 ITPR3

7.00e-048607210GO:0097447
GeneOntologyCellularComponentL-type voltage-gated calcium channel complex

CACNA1C CACNA1D

7.55e-0412722GO:1990454
GeneOntologyCellularComponentrecycling endosome

SLC9A9 ATG9B CFTR ATP13A3 VAMP8

1.01e-03222725GO:0055037
GeneOntologyCellularComponentCatSper complex

CATSPER2 CATSPER4

1.19e-0315722GO:0036128
GeneOntologyCellularComponentvaricosity

CD40 CRHR2

1.19e-0315722GO:0043196
GeneOntologyCellularComponentlate endosome

SLC9A9 SLC38A9 ADAM30 ATP13A3 VAMP8 CRHR1

1.26e-03348726GO:0005770
GeneOntologyCellularComponentpresynaptic active zone

CACNA1A CACNA1B CACNA1D IQSEC2

1.43e-03141724GO:0048786
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN3A SCN5A

1.54e-0317722GO:0001518
GeneOntologyCellularComponentsarcomere

CACNA1C CACNA1D SCN5A RYR1 RYR2

1.68e-03249725GO:0030017
GeneOntologyCellularComponentendosome

SLC9A9 ATG9B SLC38A9 CFTR ATP6V0A4 ADAM30 GCGR ATP13A3 VAMP8 AQP4 CRHR1

2.06e-0311677211GO:0005768
GeneOntologyCellularComponentendocytic vesicle

SLC9A9 CFTR ATP6V0A4 VAMP8 HVCN1 CD163

2.08e-03384726GO:0030139
GeneOntologyCellularComponentphagocytic vesicle

SLC9A9 ATP6V0A4 VAMP8 HVCN1

2.12e-03157724GO:0045335
GeneOntologyCellularComponentmyofibril

CACNA1C CACNA1D SCN5A RYR1 RYR2

2.51e-03273725GO:0030016
GeneOntologyCellularComponentcontractile muscle fiber

CACNA1C CACNA1D SCN5A RYR1 RYR2

3.26e-03290725GO:0043292
GeneOntologyCellularComponentsarcoplasmic reticulum

RYR1 RYR2 ITPR3

3.49e-0388723GO:0016529
GeneOntologyCellularComponentapical part of cell

CACNA1D CFTR ATP6V0A4 SCNN1G HVCN1 CRHR1 ITPR3

4.23e-03592727GO:0045177
GeneOntologyCellularComponentribbon synapse

CACNA1D IQSEC2

5.43e-0332722GO:0097470
GeneOntologyCellularComponentsecretory granule membrane

SPACA1 PTAFR VAMP8 HVCN1 ITPR3

5.54e-03329725GO:0030667
GeneOntologyCellularComponentearly endosome membrane

SLC9A9 CFTR ATP13A3 VAMP8

6.18e-03212724GO:0031901
GeneOntologyCellularComponentapical plasma membrane

CACNA1D CFTR ATP6V0A4 SCNN1G HVCN1 ITPR3

6.62e-03487726GO:0016324
GeneOntologyCellularComponentvacuolar membrane

SLC38A9 CFTR ATP6V0A4 TMEM138 VAMP8 TSPAN1

8.00e-03507726GO:0005774
GeneOntologyCellularComponentnuclear outer membrane

DHCR7 ITPR3

8.39e-0340722GO:0005640
GeneOntologyCellularComponentside of membrane

CD40 SCNN1G ADAM30 AQP4 CD163 RYR1 RYR2 ITPR3

1.03e-02875728GO:0098552
GeneOntologyCellularComponentsarcoplasmic reticulum membrane

RYR1 RYR2

1.05e-0245722GO:0033017
GeneOntologyCellularComponentsmooth endoplasmic reticulum

RYR1 RYR2

1.10e-0246722GO:0005790
GeneOntologyCellularComponentcilium

CACNA1F SLC9C1 CALCR CATSPER2 CATSPER4 TMEM138 IFT122 HVCN1

1.19e-02898728GO:0005929
GeneOntologyCellularComponentendoplasmic reticulum membrane

CYP1A1 TPTE ATG9B DHCR7 CFTR SSR3 RFT1 RYR1 RYR2 ITPR3

1.28e-0212937210GO:0005789
GeneOntologyCellularComponentpostsynaptic membrane

CACNA1A CACNA1C CACNA1E IQSEC2 CRHR1

1.29e-02405725GO:0045211
GeneOntologyCellularComponentendoplasmic reticulum subcompartment

CYP1A1 TPTE ATG9B DHCR7 CFTR SSR3 RFT1 RYR1 RYR2 ITPR3

1.32e-0212997210GO:0098827
MousePhenoabnormal miniature excitatory postsynaptic currents

CACNA1A CACNA1B SLC9A9 KALRN IQSEC2 RYR2

6.64e-06116566MP:0004753
MousePhenoatrial fibrillation

CACNA1D SCN5A RYR2

7.16e-0610563MP:0008543
MousePhenoabnormal respiratory epithelial sodium ion transmembrane transport

CFTR SCNN1G

1.58e-052562MP:0014181
MousePhenodecreased respiratory epithelial sodium ion transmembrane transport

CFTR SCNN1G

1.58e-052562MP:0014182
MousePhenofibrillation

CACNA1D SCN5A RYR2

2.15e-0514563MP:0006109
MousePhenoabnormal myocardial fiber physiology

CACNA1C CACNA1D SCN5A CRHR2 RYR2

2.92e-0590565MP:0004215
MousePhenoabnormal behavioral response to xenobiotic

CACNA1A CACNA1B IQSEC2 AQP4 CRHR1 RYR1 RYR2 KCNH3

2.94e-05309568MP:0009745
MousePhenoabnormal social/conspecific interaction behavior

CACNA1A CACNA1B CACNA1C SLC9A9 KALRN IQSEC2 CRHR2 CHST3 ITPR3

4.04e-05421569MP:0002557
MousePhenoabnormal nervous system electrophysiology

CACNA1A CACNA1B CACNA1D SLC9A9 KALRN SCN5A RYR2 KCNH3

4.59e-05329568MP:0002272
MousePhenoabnormal myocardial fiber sodium currents

SCN5A RYR2

4.72e-053562MP:0020347
MousePhenoabnormal intestinal epithelial sodium ion transmembrane transport

CFTR SCNN1G

4.72e-053562MP:0014204
MousePhenodecreased intestinal epithelial sodium ion transmembrane transport

CFTR SCNN1G

4.72e-053562MP:0014206
MousePhenoabnormal intestinal epithelial transmembrane transport

CFTR SCNN1G

4.72e-053562MP:0014202
MousePhenoabnormal respiratory epithelial transmembrane transport

CFTR SCNN1G

9.41e-054562MP:0014026
MousePhenoabnormal sarcoplasmic reticulum morphology

COL6A3 RYR1 RYR2

1.02e-0423563MP:0004088
MousePhenoirregular heartbeat

CACNA1C CACNA1D SCN5A RYR2

1.84e-0471564MP:0001636
MousePhenoabnormal action potential

CACNA1A CACNA1D KALRN SCN5A RYR2

1.87e-04133565MP:0005402
MousePhenoabnormal synaptic transmission

CACNA1A CACNA1B CACNA1C CACNA1E SLC9A9 KALRN DHCR7 IQSEC2 TSPAN6 TMEM138 RYR2 KCNH3 CHST3

2.44e-0410705613MP:0003635
MousePhenoabnormal liquid preference

CACNA1B CRHR1 ITPR3

2.53e-0431563MP:0001423
MousePhenoabnormal synaptic physiology

CACNA1A CACNA1B CACNA1C CACNA1E SLC9A9 KALRN DHCR7 IQSEC2 TSPAN6 TMEM138 RYR2 KCNH3 CHST3

2.58e-0410765613MP:0021009
MousePhenoabnormal muscle electrophysiology

CACNA1A CACNA1C RYR1

2.78e-0432563MP:0004145
MousePhenoabnormal channel response

CACNA1A CACNA1B CACNA1E

3.05e-0433563MP:0003484
MousePhenopancreatic acinar cell zymogen granule accumulation

CFTR VAMP8

3.27e-047562MP:0009161
MousePhenoventricular fibrillation

SCN5A RYR2

3.27e-047562MP:0006110
MousePhenoabnormal pancreatic alpha cell number

CACNA1D CACNA1E GCGR

3.64e-0435563MP:0020577
MousePhenoabnormal drinking behavior

CACNA1B ATP6V0A4 VAMP8 CRHR1 ITPR3

4.28e-04159565MP:0001422
MousePhenoabnormal CNS synaptic transmission

CACNA1A CACNA1B CACNA1C SLC9A9 KALRN DHCR7 IQSEC2 TSPAN6 TMEM138 RYR2 KCNH3 CHST3

4.33e-049855612MP:0002206
MousePhenothick ventricular wall

FAT3 SCN5A TMEM138 RYR2

4.77e-0491564MP:0002953
MousePhenoabnormal circulating glucagon level

CACNA1B CACNA1E GCGR

5.42e-0440563MP:0002695
MousePhenoabnormal myocardial fiber currents

SCN5A RYR2

5.57e-049562MP:0020345
MousePhenoasthenozoospermia

EPHB6 TPTE SLC9C1 CATSPER2 SPACA1 CATSPER4 CFTR

5.74e-04362567MP:0002675
MousePhenoabnormal pancreatic acinar cell morphology

CFTR GCGR VAMP8

5.83e-0441563MP:0009146
MousePhenoabnormal social investigation

CACNA1C SLC9A9 IQSEC2 CRHR2 ITPR3

5.96e-04171565MP:0001360
MousePhenoabnormal pH regulation

SLC9A9 ATP6V0A4 RYR1

6.26e-0442563MP:0004043
MousePhenoabnormal pancreatic acinus morphology

CFTR GCGR VAMP8

6.71e-0443563MP:0009145
MousePhenoabnormal excitatory postsynaptic potential

CACNA1A CACNA1B SLC9A9 TSPAN6

7.33e-04102564MP:0002912
MousePhenodecreased vocalization

CACNA1C SLC9A9 IQSEC2

8.18e-0446563MP:0020351
MousePhenoabnormal pancreatic alpha cell morphology

CACNA1D CACNA1E GCGR

8.18e-0446563MP:0005216
MousePhenoimpaired social transmission of food preference

CACNA1B ITPR3

8.47e-0411562MP:0002969
MousePhenoabnormal fear/anxiety-related behavior

CACNA1A CACNA1B CACNA1C CACNA1E KALRN IQSEC2 ATP13A3 OR5AR1 CRHR1 CRHR2 ITPR3

9.04e-049195611MP:0002065
MousePhenodecreased physiological sensitivity to xenobiotic

CYP1A1 CACNA1E KALRN CFTR IFT122 AQP4

9.07e-04283566MP:0008874
MousePhenoabnormal sperm motility

EPHB6 TPTE SLC9C1 CATSPER2 SPACA1 CATSPER4 CFTR

1.05e-03401567MP:0002674
DomainIon_trans_dom

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9C1 CATSPER2 CATSPER4 SCN3A SCN5A HVCN1 RYR1 RYR2 KCNH3 ITPR3

3.95e-231147017IPR005821
DomainIon_trans

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TPTE SLC9C1 CATSPER2 CATSPER4 SCN3A SCN5A HVCN1 RYR1 RYR2 KCNH3 ITPR3

3.95e-231147017PF00520
DomainChannel_four-helix_dom

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 SCN3A SCN5A HVCN1

1.45e-16577011IPR027359
Domain-

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CATSPER2 CATSPER4 SCN3A SCN5A HVCN1

1.45e-165770111.20.120.350
DomainVDCC_a1su_IQ

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

1.55e-147706IPR014873
DomainGPHH

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

1.55e-147706PF16905
DomainGPHH_dom

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

1.55e-147706IPR031649
DomainCa_chan_IQ

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

1.55e-147706SM01062
DomainCa_chan_IQ

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

1.55e-147706PF08763
DomainVDCCAlpha1

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

4.62e-1310706IPR002077
DomainCAC1F_C

CACNA1C CACNA1D CACNA1F

5.04e-083703IPR031688
DomainCAC1F_C

CACNA1C CACNA1D CACNA1F

5.04e-083703PF16885
DomainVDCC_L_a1su

CACNA1C CACNA1D CACNA1F

2.01e-074703IPR005446
DomainRIH_assoc

RYR1 RYR2 ITPR3

1.00e-066703PF08454
DomainRIH_assoc-dom

RYR1 RYR2 ITPR3

1.00e-066703IPR013662
DomainRIH_dom

RYR1 RYR2 ITPR3

1.00e-066703IPR000699
DomainIns145_P3_rcpt

RYR1 RYR2 ITPR3

1.00e-066703IPR014821
DomainRyanodine_recept-rel

RYR1 RYR2 ITPR3

1.00e-066703IPR015925
Domain-

RYR1 RYR2 ITPR3

1.00e-0667031.25.10.30
DomainRYDR_ITPR

RYR1 RYR2 ITPR3

1.00e-066703PF01365
DomainIns145_P3_rec

RYR1 RYR2 ITPR3

1.00e-066703PF08709
DomainG_PROTEIN_RECEP_F2_2

CALCR ADGRE4P GCGR CRHR1 CRHR2

1.19e-0650705PS00650
Domain7tm_2

CALCR ADGRE4P GCGR CRHR1 CRHR2

1.19e-0650705PF00002
DomainHormR

CALCR GCGR CRHR1 CRHR2

2.16e-0625704SM00008
DomainGPCR_2_secretin-like

CALCR ADGRE4P GCGR CRHR1 CRHR2

2.98e-0660705IPR000832
DomainG_PROTEIN_RECEP_F2_4

CALCR ADGRE4P GCGR CRHR1 CRHR2

3.23e-0661705PS50261
DomainHRM

CALCR GCGR CRHR1 CRHR2

3.46e-0628704PF02793
DomainMIR

RYR1 RYR2 ITPR3

5.94e-0610703PS50919
DomainMIR

RYR1 RYR2 ITPR3

5.94e-0610703PF02815
DomainMIR

RYR1 RYR2 ITPR3

5.94e-0610703SM00472
DomainMIR_motif

RYR1 RYR2 ITPR3

5.94e-0610703IPR016093
DomainGPCR_2_secretin-like_CS

CALCR GCGR CRHR1 CRHR2

7.71e-0634704IPR017983
DomainG_PROTEIN_RECEP_F2_1

CALCR GCGR CRHR1 CRHR2

1.49e-0540704PS00649
DomainGPCR_2_extracellular_dom

CALCR GCGR CRHR1 CRHR2

1.49e-0540704IPR001879
DomainG_PROTEIN_RECEP_F2_3

CALCR GCGR CRHR1 CRHR2

1.49e-0540704PS50227
DomainRyanrecept_TM4-6

RYR1 RYR2

4.14e-053702IPR009460
DomainRyR

RYR1 RYR2

4.14e-053702PF02026
DomainGPCR_2_CRF_rcpt

CRHR1 CRHR2

4.14e-053702IPR003051
DomainRyanodine_rcpt

RYR1 RYR2

4.14e-053702IPR003032
DomainRR_TM4-6

RYR1 RYR2

4.14e-053702PF06459
DomainRyan_recept

RYR1 RYR2

4.14e-053702IPR013333
DomainGPCR_2-like

CALCR GCGR CRHR1 CRHR2

7.53e-0560704IPR017981
DomainNa_trans_cytopl

SCN3A SCN5A

2.06e-046702PF11933
DomainNa_trans_cytopl

SCN3A SCN5A

2.06e-046702IPR024583
DomainNa_channel_asu

SCN3A SCN5A

6.11e-0410702IPR001696
DomainNa_trans_assoc

SCN3A SCN5A

6.11e-0410702IPR010526
DomainNa_trans_assoc

SCN3A SCN5A

6.11e-0410702PF06512
DomainOlfact_rcpt

OR4C3 OR6B3 OR6N2 OR6C1 OR5AR1 OR6B2 OR52J3

6.64e-04393707IPR000725
DomainEF-hand-dom_pair

CACNA1B CACNA1C CACNA1F SCN3A RYR1 RYR2

7.19e-04287706IPR011992
DomainCation/H_exchanger_CPA1

SLC9A9 SLC9C1

7.45e-0411702IPR018422
DomainGPCR_Rhodpsn_7TM

OR4C3 OR6B3 OR6N2 OR6C1 GPR141 PTAFR OR5AR1 OR6B2 OR52J3

8.59e-04670709IPR017452
Domain7tm_1

OR4C3 OR6B3 OR6N2 OR6C1 GPR141 PTAFR OR5AR1 OR6B2 OR52J3

9.24e-04677709PF00001
DomainG_PROTEIN_RECEP_F1_1

OR4C3 OR6B3 OR6N2 OR6C1 GPR141 PTAFR OR5AR1 OR6B2 OR52J3

1.00e-03685709PS00237
DomainG_PROTEIN_RECEP_F1_2

OR4C3 OR6B3 OR6N2 OR6C1 GPR141 PTAFR OR5AR1 OR6B2 OR52J3

1.07e-03691709PS50262
DomainGPCR_Rhodpsn

OR4C3 OR6B3 OR6N2 OR6C1 GPR141 PTAFR OR5AR1 OR6B2 OR52J3

1.08e-03692709IPR000276
DomainNa_H_Exchanger

SLC9A9 SLC9C1

1.22e-0314702PF00999
DomainCation/H_exchanger

SLC9A9 SLC9C1

1.22e-0314702IPR006153
DomainTetraspanin_CS

TSPAN6 TSPAN1

2.78e-0321702IPR018503
DomainTM4_1

TSPAN6 TSPAN1

4.25e-0326702PS00421
PathwayKEGG_MEDICUS_REFERENCE_CA2_CAM_VGCC_RYR_SIGNALING_PATHWAY

CACNA1A CACNA1B CACNA1C CACNA1E RYR1 RYR2

1.88e-1211596M47958
PathwayKEGG_MEDICUS_REFERENCE_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

3.95e-1023596M47666
PathwayKEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

6.89e-1025596M47948
PathwayKEGG_CALCIUM_SIGNALING_PATHWAY

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F PTAFR RYR1 RYR2 ITPR3

2.94e-091785910M2890
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_VGCC_CA2_APOPTOTIC_PATHWAY

CACNA1B CACNA1C CACNA1D CACNA1F

4.12e-096594M47762
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E RYR1 RYR2 ITPR3

1.63e-07147598MM15854
PathwayWP_CALCIUM_REGULATION_IN_CARDIAC_CELLS

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E RYR1 RYR2 ITPR3

2.01e-07151598M39329
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1A CACNA1C CACNA1D CACNA1E GCGR ITPR3

5.22e-0772596MM14631
PathwayKEGG_TYPE_II_DIABETES_MELLITUS

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E

1.45e-0647595M19708
PathwayKEGG_TASTE_TRANSDUCTION

CACNA1A CACNA1B TAS2R1 SCNN1G ITPR3

2.42e-0652595M5785
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

CALCR GCGR CRHR1 CRHR2

2.76e-0624594M39643
PathwayWP_GPCRS_CLASS_B_SECRETINLIKE

CALCR GCGR CRHR1 CRHR2

2.76e-0624594MM15992
PathwayREACTOME_FERTILIZATION

CATSPER2 CATSPER4 ADAM30 HVCN1

3.86e-0626594M26922
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

CACNA1A CACNA1C CACNA1D CACNA1E ITPR3

5.37e-0661595MM15071
PathwayREACTOME_INTEGRATION_OF_ENERGY_METABOLISM

CACNA1A CACNA1C CACNA1D CACNA1E GCGR ITPR3

5.70e-06108596M17034
PathwayREACTOME_SPERM_MOTILITY_AND_TAXES

CATSPER2 CATSPER4 HVCN1

5.75e-069593M26935
PathwayREACTOME_SPERM_MOTILITY_AND_TAXES

CATSPER2 CATSPER4 HVCN1

5.75e-069593MM14548
PathwayREACTOME_REPRODUCTION

CATSPER2 CATSPER4 ADAM30 HVCN1

6.99e-0630594MM17211
PathwayREACTOME_SENSORY_PERCEPTION

CACNA1D TAS2R1 OR4C3 OR6B3 OR6N2 OR6C1 SCN3A SCNN1G OR5AR1 OR6B2 ITPR3 OR52J3

1.02e-056365912M41834
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B CACNA1E

1.12e-0511593MM14498
PathwayREACTOME_PRESYNAPTIC_DEPOLARIZATION_AND_CALCIUM_CHANNEL_OPENING

CACNA1A CACNA1B CACNA1E

1.12e-0511593M26913
PathwayREACTOME_CARDIAC_CONDUCTION

CACNA1C SCN3A SCN5A RYR1 RYR2 ITPR3

1.65e-05130596M27454
PathwayREACTOME_REGULATION_OF_INSULIN_SECRETION

CACNA1A CACNA1C CACNA1D CACNA1E ITPR3

1.81e-0578595M1921
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_ABETA_TO_VGCC_CA2_APOPTOTIC_PATHWAY_N01004

CACNA1C CACNA1D CACNA1F

2.45e-0514593M47692
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

TAS2R1 SCN3A SCNN1G ITPR3

4.32e-0547594M42524
PathwayKEGG_MEDICUS_VARIANT_SCRAPIE_CONFORMATION_PRPSC_TO_MGLUR5_CA2_APOPTOTIC_PATHWAY

RYR1 RYR2 ITPR3

6.43e-0519593M47760
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

CALCR GCGR CRHR1 CRHR2

1.13e-0460594MM14964
PathwayWP_GPCRS_NONODORANT

TAS2R1 CALCR ADGRE4P GCGR PTAFR CRHR1 CRHR2

1.16e-04266597MM15843
PathwayREACTOME_MUSCLE_CONTRACTION

CACNA1C SCN3A SCN5A RYR1 RYR2 ITPR3

1.98e-04203596M5485
PathwayKEGG_LONG_TERM_DEPRESSION

CACNA1A CRHR1 RYR1 ITPR3

2.07e-0470594M8232
PathwayWP_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY

CACNA1C CACNA1D CACNA1F RYR2

2.56e-0474594M39462
PathwayKEGG_ARRHYTHMOGENIC_RIGHT_VENTRICULAR_CARDIOMYOPATHY_ARVC

CACNA1C CACNA1D CACNA1F RYR2

2.56e-0474594M16376
PathwayWP_ALZHEIMERS_DISEASE

CACNA1C CACNA1D CACNA1F ITPR3

2.56e-0474594MM15962
PathwayREACTOME_SENSORY_PERCEPTION_OF_TASTE

TAS2R1 SCNN1G ITPR3

2.88e-0431593MM15691
PathwayREACTOME_PHASE_0_RAPID_DEPOLARISATION

CACNA1C SCN3A SCN5A

3.17e-0432593M27455
PathwayKEGG_CARDIAC_MUSCLE_CONTRACTION

CACNA1C CACNA1D CACNA1F RYR2

3.29e-0479594M17673
PathwayKEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM

CACNA1C CACNA1D CACNA1F RYR2

3.97e-0483594M8728
PathwayKEGG_DILATED_CARDIOMYOPATHY

CACNA1C CACNA1D CACNA1F RYR2

5.41e-0490594M835
PathwayWP_MAPK_SIGNALING

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

5.52e-04246596M39597
PathwayREACTOME_CLASS_B_2_SECRETIN_FAMILY_RECEPTORS

CALCR GCGR CRHR1 CRHR2

6.37e-0494594M797
PathwayREACTOME_NCAM1_INTERACTIONS

CACNA1C CACNA1D COL6A3

7.12e-0442593M7169
PathwayKEGG_GNRH_SIGNALING_PATHWAY

CACNA1C CACNA1D CACNA1F ITPR3

8.35e-04101594M1979
PathwayKEGG_MAPK_SIGNALING_PATHWAY

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

8.48e-04267596M10792
PathwayREACTOME_CARDIAC_CONDUCTION

CACNA1C RYR1 RYR2 ITPR3

8.99e-04103594MM15196
PathwayREACTOME_ION_CHANNEL_TRANSPORT

SLC9C1 ATP6V0A4 SCNN1G RYR1 RYR2

9.91e-04183595M997
PathwayREACTOME_STIMULI_SENSING_CHANNELS

SLC9C1 SCNN1G RYR1 RYR2

1.00e-03106594M27200
PathwayKEGG_OLFACTORY_TRANSDUCTION

OR4C3 OR6B3 OR6N2 OR6C1 OR5AR1 OR6B2 OR52J3

1.14e-03389597M14091
PathwayWP_CELLTYPE_DEPENDENT_SELECTIVITY_OF_CCK2R_SIGNALING

RYR1 RYR2

1.30e-0313592M39589
PathwayKEGG_VASCULAR_SMOOTH_MUSCLE_CONTRACTION

CACNA1C CACNA1D CACNA1F ITPR3

1.35e-03115594M9387
PathwayREACTOME_ION_HOMEOSTASIS

RYR1 RYR2 ITPR3

1.48e-0354593M27460
PathwayREACTOME_ION_HOMEOSTASIS

RYR1 RYR2 ITPR3

1.48e-0354593MM15202
PathwayREACTOME_OLFACTORY_SIGNALING_PATHWAY

OR4C3 OR6B3 OR6N2 OR6C1 OR5AR1 OR6B2 OR52J3

1.71e-03417597M4072
PathwayWP_AIRWAY_SMOOTH_MUSCLE_CELL_CONTRACTION

RYR1 ITPR3

1.99e-0316592M40060
PathwayREACTOME_NCAM_SIGNALING_FOR_NEURITE_OUT_GROWTH

CACNA1C CACNA1D COL6A3

2.31e-0363593M11187
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

CALCR GCGR CRHR1 CRHR2

3.00e-03143594MM15055
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

SLC9A9 SLC9C1 ABCA6 CFTR ATP6V0A4 SCNN1G AQP4 RYR1 RYR2

3.30e-03736599M27287
PathwayKEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING

CACNA1C RYR2

3.44e-0321592M47950
PathwayWP_DRAVET_SYNDROME_SCN1AA1783V_POINT_MUTATION_MODEL

CACNA1A CACNA1B SCN3A

3.52e-0373593MM16641
PathwayWP_AFFECTED_PATHWAYS_IN_DUCHENNE_MUSCULAR_DYSTROPHY

CACNA1F RYR1 ITPR3

3.66e-0374593M48080
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

CRHR1 RYR1 RYR2 ITPR3

3.91e-03154594MM15974
PathwayWP_MYOMETRIAL_RELAXATION_AND_CONTRACTION_PATHWAYS

CRHR1 RYR1 RYR2 ITPR3

4.10e-03156594M39475
PathwayREACTOME_G_ALPHA_S_SIGNALLING_EVENTS

CALCR GCGR CRHR1 CRHR2

4.19e-03157594M4904
PathwayREACTOME_REPRODUCTION

CATSPER2 CATSPER4 ADAM30 HVCN1

4.28e-03158594M26956
PathwayREACTOME_MUSCLE_CONTRACTION

CACNA1C RYR1 RYR2 ITPR3

5.00e-03165594MM15026
PathwayKEGG_ALZHEIMERS_DISEASE

CACNA1C CACNA1D CACNA1F ITPR3

5.10e-03166594M16024
PathwayREACTOME_SIGNALING_BY_GPCR

TAS2R1 CALCR KALRN GCGR PTAFR CRHR1 CRHR2 ITPR3

5.23e-03646598MM14962
PathwayKEGG_NEUROACTIVE_LIGAND_RECEPTOR_INTERACTION

CALCR GCGR PTAFR CRHR1 CRHR2

5.52e-03272595M13380
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

6.46e-173872930786075
Pubmed

Large-scale analysis of ion channel gene expression in the mouse heart during perinatal development.

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCN3A SCN5A SCNN1G RYR2 KCNH3

6.82e-15139721116985003
Pubmed

Functional disorders of the sympathetic nervous system in mice lacking the alpha 1B subunit (Cav 2.2) of N-type calcium channels.

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E

3.30e-14572511296258
Pubmed

Antinociceptive effect of different types of calcium channel inhibitors and the distribution of various calcium channel alpha 1 subunits in the dorsal horn of spinal cord in mice.

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E

3.30e-14572515451373
Pubmed

Voltage-activated calcium channel expression profiles in mouse brain and cultured hippocampal neurons.

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

3.14e-131572620188150
Pubmed

Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

3.14e-131572624453333
Pubmed

International Union of Pharmacology. XLVIII. Nomenclature and structure-function relationships of voltage-gated calcium channels.

CACNA1A CACNA1B CACNA1C CACNA1E CACNA1F

4.13e-12972516382099
Pubmed

Enhanced expression of L-type Cav1.3 calcium channels in murine embryonic hearts from Cav1.2-deficient mice.

CACNA1C CACNA1D CACNA1E CACNA1F

5.88e-10772412900400
Pubmed

Evolutionary insights into T-type Ca2+ channel structure, function, and ion selectivity from the Trichoplax adhaerens homologue.

CACNA1B CACNA1D CACNA1E CACNA1F

1.17e-09872428330839
Pubmed

The intracellular C-terminus confers compartment-specific targeting of voltage-gated calcium channels.

CACNA1A CACNA1B CACNA1E

8.51e-09372338996073
Pubmed

Molecular Basis of Regulating High Voltage-Activated Calcium Channels by S-Nitrosylation.

CACNA1A CACNA1B CACNA1C

8.51e-09372326507659
Pubmed

Truncation of murine CaV1.2 at Asp 1904 increases CaV1.3 expression in embryonic atrial cardiomyocytes.

CACNA1A CACNA1C CACNA1D

8.51e-09372323338940
Pubmed

Distinct roles for Cav2.1-2.3 in activity-dependent synaptic dynamics.

CACNA1A CACNA1B CACNA1E

8.51e-09372324523520
Pubmed

L-type voltage-dependent calcium channel alpha subunit 1C is a novel candidate gene associated with secondary hyperparathyroidism: an application of haplotype-based analysis for multiple linked single nucleotide polymorphisms.

CACNA1C CACNA1D CACNA1E CALCR SPACA1 RYR1 RYR2

2.02e-0814372720424473
Pubmed

Beta-adrenergic-regulated phosphorylation of the skeletal muscle Ca(V)1.1 channel in the fight-or-flight response.

CACNA1C CACNA1D CACNA1F

3.40e-08472320937870
Pubmed

Cerebellar granule cell signaling is indispensable for normal motor performance.

CACNA1A CACNA1B CACNA1E

3.40e-08472337141091
Pubmed

Synapse and Active Zone Assembly in the Absence of Presynaptic Ca2+ Channels and Ca2+ Entry.

CACNA1A CACNA1B CACNA1E

3.40e-08472332616470
Pubmed

A protein phosphatase 2calpha-Ca2+ channel complex for dephosphorylation of neuronal Ca2+ channels phosphorylated by protein kinase C.

CACNA1A CACNA1B CACNA1C

3.40e-08472315728831
Pubmed

Interactions of Rabconnectin-3 with Cav2 calcium channels.

CACNA1A CACNA1B WDR7

3.40e-08472331253182
Pubmed

G protein-gated inhibitory module of N-type (ca(v)2.2) ca2+ channels.

CACNA1A CACNA1B CACNA1C

3.40e-08472315953418
Pubmed

Chromosomal localization of the human genes for alpha 1A, alpha 1B, and alpha 1E voltage-dependent Ca2+ channel subunits.

CACNA1A CACNA1B CACNA1E

8.48e-0857238825650
Pubmed

Identification of a cardiac isoform of the murine calcium channel alpha1C (Cav1.2-a) subunit and its preferential binding with the beta2 subunit.

CACNA1A CACNA1B CACNA1C

8.48e-08572316787652
Pubmed

Kv2.1 mediates spatial and functional coupling of L-type calcium channels and ryanodine receptors in mammalian neurons.

CACNA1C CACNA1D RYR2

8.48e-08572331663850
Pubmed

Voltage-gated calcium channels in developing GnRH-1 neuronal system in the mouse.

CACNA1B CACNA1C CACNA1D

1.69e-07672316029198
Pubmed

Roles of I(f) and intracellular Ca2+ release in spontaneous activity of ventricular cardiomyocytes during murine embryonic development.

RYR1 RYR2 ITPR3

1.69e-07672323463619
Pubmed

An action potential initiation mechanism in distal axons for the control of dopamine release.

CACNA1A CACNA1B CACNA1E

1.69e-07672335324301
Pubmed

Essential Roles of Intracellular Calcium Release Channels in Muscle, Brain, Metabolism, and Aging.

RYR1 RYR2 ITPR3

1.69e-07672325966694
Pubmed

Alpha-neurexins couple Ca2+ channels to synaptic vesicle exocytosis.

CACNA1A CACNA1B CACNA1E

1.69e-07672312827191
Pubmed

A calcium-induced calcium release mechanism supports luteinizing hormone-induced testosterone secretion in mouse Leydig cells.

RYR1 RYR2 ITPR3

1.69e-07672320519450
Pubmed

ER stress disrupts Ca2+-signaling complexes and Ca2+ regulation in secretory and muscle cells from PERK-knockout mice.

CACNA1C RYR2 ITPR3

1.69e-07672316352659
Pubmed

Direct interaction of gbetagamma with a C-terminal gbetagamma-binding domain of the Ca2+ channel alpha1 subunit is responsible for channel inhibition by G protein-coupled receptors.

CACNA1A CACNA1B CACNA1E

1.69e-0767239238069
Pubmed

IP3Rs are sufficient for dendritic cell Ca2+ signaling in the absence of RyR1.

RYR1 RYR2 ITPR3

1.69e-07672316844763
Pubmed

Developmental expression of the calcium release channels during early neurogenesis of the mouse cerebral cortex.

RYR1 RYR2 ITPR3

2.96e-07772311860456
Pubmed

Rebuilding essential active zone functions within a synapse.

CACNA1A CACNA1B CACNA1E

2.96e-07772335176221
Pubmed

Sequential docking, molecular differentiation, and positioning of T-Tubule/SR junctions in developing mouse skeletal muscle.

CACNA1C RYR1 RYR2

4.73e-07872311784029
Pubmed

Roles of IP3R and RyR Ca2+ channels in endoplasmic reticulum stress and beta-cell death.

RYR1 RYR2 ITPR3

4.73e-07872319033399
Pubmed

A novel conditional mouse model for Nkx2-5 reveals transcriptional regulation of cardiac ion channels.

CACNA1C SCN5A RYR2

1.01e-061072326897459
Pubmed

Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study.

SPACA1 CFTR RYR2

1.39e-061172317903301
Pubmed

NCAM induces CaMKIIalpha-mediated RPTPalpha phosphorylation to enhance its catalytic activity and neurite outgrowth.

CACNA1C CACNA1D CACNA1F

1.39e-061172318809727
Pubmed

New molecular components supporting ryanodine receptor-mediated Ca(2+) release: roles of junctophilin and TRIC channel in embryonic cardiomyocytes.

CACNA1C RYR1 RYR2

1.85e-061272319095005
Pubmed

Loss of receptor activity-modifying protein 2 in mice causes placental dysfunction and alters PTH1R regulation.

CALCR GCGR CRHR1

2.40e-061372328727763
Pubmed

Regulation of neuronal voltage-gated sodium channels by the ubiquitin-protein ligases Nedd4 and Nedd4-2.

SCN3A SCN5A SCNN1G

2.40e-061372315123669
Pubmed

MED12 regulates a transcriptional network of calcium-handling genes in the heart.

CACNA1D RYR1 RYR2

3.05e-061472328724790
Pubmed

Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling.

CRHR1 CRHR2

4.23e-06272219098121
Pubmed

Loss of Nav1.5 expression and function in murine atria containing the RyR2-P2328S gain-of-function mutation.

SCN5A RYR2

4.23e-06272223723061
Pubmed

Blocking the R-type (Cav2.3) Ca2+ channel enhanced morphine analgesia and reduced morphine tolerance.

CACNA1B CACNA1E

4.23e-06272215610184
Pubmed

Stable respiratory activity requires both P/Q-type and N-type voltage-gated calcium channels.

CACNA1A CACNA1B

4.23e-06272223426690
Pubmed

Novel corticotropin-releasing hormone receptor genes (CRHR1 and CRHR2) linkage to and association with polycystic ovary syndrome.

CRHR1 CRHR2

4.23e-06272237543650
Pubmed

Different roles attributed to Cav1 channel subtypes in spontaneous action potential firing and fine tuning of exocytosis in mouse chromaffin cells.

CACNA1C CACNA1D

4.23e-06272221054386
Pubmed

Skeletal and cardiac ryanodine receptors exhibit different responses to Ca2+ overload and luminal ca2+.

RYR1 RYR2

4.23e-06272217259277
Pubmed

Ryanodine receptor oligomeric interaction: identification of a putative binding region.

RYR1 RYR2

4.23e-06272214722100
Pubmed

Structural and functional interactions within ryanodine receptor.

RYR1 RYR2

4.23e-06272226009179
Pubmed

Associations of Variants in the CACNA1A and CACNA1C Genes With Longitudinal Blood Pressure Changes and Hypertension Incidence: The GenSalt Study.

CACNA1A CACNA1C

4.23e-06272227418245
Pubmed

Voltage-Gated Cav1 Channels in Disorders of Vision and Hearing.

CACNA1D CACNA1F

4.23e-06272225966695
Pubmed

Genetic variation in the corticotrophin-releasing factor receptors: identification of single-nucleotide polymorphisms and association studies with obesity in UK Caucasians.

CRHR1 CRHR2

4.23e-06272214724656
Pubmed

Structure and Function of the Human Ryanodine Receptors and Their Association with Myopathies-Present State, Challenges, and Perspectives.

RYR1 RYR2

4.23e-06272232899693
Pubmed

Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: prevention of Aβ-induced synaptic deficits by calcium channel blockers.

CACNA1A CACNA1B

4.23e-06272223376566
Pubmed

An improved targeted cAMP sensor to study the regulation of adenylyl cyclase 8 by Ca2+ entry through voltage-gated channels.

CACNA1C CACNA1D

4.23e-06272224086669
Pubmed

Expression of corticotropin-releasing hormone receptor type 1 and type 2 in human pregnant myometrium.

CRHR1 CRHR2

4.23e-06272217959885
Pubmed

Differential regulation of prostaglandin production mediated by corticotropin-releasing hormone receptor type 1 and type 2 in cultured human placental trophoblasts.

CRHR1 CRHR2

4.23e-06272218325997
Pubmed

Different effects of chronic social defeat on social behavior and the brain CRF system in adult male C57 mice with different susceptibilities.

CRHR1 CRHR2

4.23e-06272232057826
Pubmed

Differential zinc permeation and blockade of L-type Ca2+ channel isoforms Cav1.2 and Cav1.3.

CACNA1C CACNA1D

4.23e-06272226049024
Pubmed

Wide long lasting perinuclear Ca2+ release events generated by an interaction between ryanodine and IP3 receptors in canine Purkinje cells.

RYR2 ITPR3

4.23e-06272218586264
Pubmed

Genetic polymorphisms of L-type calcium channel alpha1C and alpha1D subunit genes are associated with sensitivity to the antihypertensive effects of L-type dihydropyridine calcium-channel blockers.

CACNA1C CACNA1D

4.23e-06272219225208
Pubmed

Ca1.2 and CaV1.3 neuronal L-type calcium channels: differential targeting and signaling to pCREB.

CACNA1C CACNA1D

4.23e-06272216706838
Pubmed

Effect of CRHR1 and CRHR2 gene polymorphisms and childhood trauma in suicide attempt.

CRHR1 CRHR2

4.23e-06272230874897
Pubmed

Temperature-sensitive Cav1.2 calcium channels support intrinsic firing of pyramidal neurons and provide a target for the treatment of febrile seizures.

CACNA1C CACNA1D

4.23e-06272223761887
Pubmed

Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.

CACNA1C CACNA1D

4.23e-06272214981074
Pubmed

CaV1.2 and CaV1.3 channel hyperactivation in mouse islet β cells exposed to type 1 diabetic serum.

CACNA1C CACNA1D

4.23e-06272225292336
Pubmed

CaV 2.1 α1  subunit motifs that control presynaptic CaV 2.1 subtype abundance are distinct from CaV 2.1 preference.

CACNA1A CACNA1B

4.23e-06272238155373
Pubmed

Ca(v)1.3 channels produce persistent calcium sparklets, but Ca(v)1.2 channels are responsible for sparklets in mouse arterial smooth muscle.

CACNA1C CACNA1D

4.23e-06272217526649
Pubmed

Ligand-activated signal transduction in the 2-cell embryo.

CACNA1C CACNA1D

4.23e-06272212606379
Pubmed

Pyrimidine-2,4,6-triones are a new class of voltage-gated L-type Ca2+ channel activators.

CACNA1C CACNA1D

4.23e-06272224941892
Pubmed

Complex Brugada syndrome inheritance in a family harbouring compound SCN5A and CACNA1C mutations.

CACNA1C SCN5A

4.23e-06272225341504
Pubmed

Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells.

CACNA1C CACNA1D

4.23e-06272222826131
Pubmed

C-terminal modulator controls Ca2+-dependent gating of Ca(v)1.4 L-type Ca2+ channels.

CACNA1D CACNA1F

4.23e-06272216921373
Pubmed

Ryanodine receptors in human pancreatic beta cells: localization and effects on insulin secretion.

RYR1 RYR2

4.23e-06272215033925
Pubmed

Transcriptional regulation of L-type calcium channel subtypes Cav1.2 and Cav1.3 by nicotine and their potential role in nicotine sensitization.

CACNA1C CACNA1D

4.23e-06272224470632
Pubmed

Functional interaction of CFTR and ENaC in sweat glands.

CFTR SCNN1G

4.23e-06272212548396
Pubmed

Corticotropin-Releasing Hormone Family and Their Receptors in the Cardiovascular System.

CRHR1 CRHR2

4.23e-06272230584229
Pubmed

Cav1.2 and Cav1.3 L-type calcium channels operate in a similar voltage range but show different coupling to Ca(2+)-dependent conductances in hippocampal neurons.

CACNA1C CACNA1D

4.23e-06272224760982
Pubmed

Estrogen alters the splicing of type 1 corticotropin-releasing hormone receptor in breast cancer cells.

CRHR1 CRHR2

4.23e-06272223821771
Pubmed

Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.

SCN5A RYR2

4.23e-06272226289036
Pubmed

Maurocalcin and its analog MCaE12A facilitate Ca2+ mobilization in cardiomyocytes.

CACNA1D RYR2

4.23e-06272233034621
Pubmed

Deletion of the L-type calcium channel Ca(V) 1.3 but not Ca(V) 1.2 results in a diminished sAHP in mouse CA1 pyramidal neurons.

CACNA1C CACNA1D

4.23e-06272220014384
Pubmed

Expression and subcellular localization of CRH and its receptors in human endometrial cancer.

CRHR1 CRHR2

4.23e-06272219433256
Pubmed

L-type calcium channels contribute to the tottering mouse dystonic episodes.

CACNA1A CACNA1C

4.23e-0627229882694
Pubmed

Localization of the calcium channel subunits Cav1.2 (alpha1C) and Cav2.3 (alpha1E) in the mouse organ of Corti.

CACNA1C CACNA1E

4.23e-06272212973680
Pubmed

Role of putative voltage-sensor countercharge D4 in regulating gating properties of CaV1.2 and CaV1.3 calcium channels.

CACNA1C CACNA1D

4.23e-06272230001160
Pubmed

Corticotropin-releasing factor receptors induce calcium mobilization through cross-talk with Gq-coupled receptors.

CRHR1 CRHR2

4.23e-06272220594969
Pubmed

Compensatory contribution of Cav2.3 channels to acetylcholine release at the neuromuscular junction of tottering mice.

CACNA1A CACNA1E

4.23e-06272216381801
Pubmed

Rescue and worsening of congenital heart block-associated electrocardiographic abnormalities in two transgenic mice.

CACNA1C CACNA1D

4.23e-06272221352396
Pubmed

Association of CRHR1 and CRHR2 with major depressive disorder and panic disorder in a Japanese population.

CRHR1 CRHR2

4.23e-06272222467522
Pubmed

Sinus node dysfunction following targeted disruption of the murine cardiac sodium channel gene Scn5a.

CACNA1D SCN5A

4.23e-06272215932895
Pubmed

Molecular nature of anomalous L-type calcium channels in mouse cerebellar granule cells.

CACNA1C CACNA1D

4.23e-06272217409250
Pubmed

Neuronal L-type calcium channels open quickly and are inhibited slowly.

CACNA1C CACNA1D

4.23e-06272216267232
Pubmed

The role of L-type voltage-gated calcium channels Cav1.2 and Cav1.3 in normal and pathological brain function.

CACNA1C CACNA1D

4.23e-06272224996399
Pubmed

Dysregulation of bladder corticotropin-releasing hormone receptor in the pathogenesis of human interstitial cystitis/bladder pain syndrome.

CRHR1 CRHR2

4.23e-06272231844086
Pubmed

Corticotropin-releasing hormone receptor (CRHR)1 and CRHR2 are both trafficking and signaling receptors for urocortin.

CRHR1 CRHR2

4.23e-06272217170072
Pubmed

Genetic analysis in post-mortem samples with micro-ischemic alterations.

SCN5A RYR2

4.23e-06272228086167
InteractionCACNA1D interactions

CACNA1A CACNA1B CACNA1C CACNA1D SCN5A RYR2

1.14e-1024656int:CACNA1D
InteractionSCN11A interactions

CACNA1A CACNA1B CACNA1C CACNA1D SCN5A

8.74e-1015655int:SCN11A
InteractionCACNA1B interactions

CACNA1A CACNA1B CACNA1C CACNA1D WDR7 SCN5A

1.91e-0937656int:CACNA1B
InteractionSCN9A interactions

CACNA1A CACNA1B CACNA1C CACNA1D SCN5A

5.83e-0921655int:SCN9A
InteractionSCN1A interactions

CACNA1A CACNA1B CACNA1C CACNA1D SCN5A

3.34e-0829655int:SCN1A
InteractionCACNA1C interactions

CACNA1A CACNA1B CACNA1C CACNA1D SCN5A RYR2

4.30e-0861656int:CACNA1C
InteractionNALCN interactions

CACNA1A CACNA1B CACNA1D SCN5A

9.63e-0814654int:NALCN
InteractionCACNA1A interactions

CACNA1A CACNA1B CACNA1C CACNA1D KALRN WDR7 SCN5A

1.38e-07123657int:CACNA1A
InteractionSCN5A interactions

CACNA1A CACNA1B CACNA1C CACNA1D SCN5A

4.12e-0747655int:SCN5A
InteractionCACNB2 interactions

CACNA1A CACNA1B CACNA1C CACNA1D

8.33e-0723654int:CACNB2
InteractionRYR2 interactions

CACNA1C CACNA1D CFTR RYR1 RYR2

1.20e-0658655int:RYR2
InteractionSCN10A interactions

CACNA1A CACNA1D SCN5A

5.19e-0611653int:SCN10A
InteractionCABP1 interactions

CACNA1A CACNA1C ITPR3

1.42e-0515653int:CABP1
InteractionRAB5C interactions

SLC9A9 WDR7 SLC38A9 DHCR7 CFTR TMPO ATP13A3 RFT1 VAMP8 ITPR3

2.08e-056006510int:RAB5C
InteractionAKAP6 interactions

CFTR RYR1 RYR2

2.11e-0517653int:AKAP6
InteractionUCN3 interactions

FAT3 CRHR1 CRHR2

5.42e-0523653int:UCN3
InteractionCACNB4 interactions

CACNA1A CACNA1B CACNA1C

7.00e-0525653int:CACNB4
InteractionTCTN3 interactions

CACNA1A SLC38A9 DHCR7 CFTR TMPO SSR3 RFT1

9.85e-05334657int:TCTN3
InteractionCACNB3 interactions

CACNA1A CACNA1B CACNA1C

1.49e-0432653int:CACNB3
InteractionUCN interactions

CRHR1 CRHR2

1.52e-046652int:UCN
InteractionCALM1 interactions

CACNA1C CALCR IQSEC2 CFTR SCN5A PTAFR CRHR1 RYR1 RYR2

1.72e-04626659int:CALM1
InteractionFADS1 interactions

ABCA6 DHCR7 GCGR ATP13A3

1.79e-0487654int:FADS1
InteractionSORCS1 interactions

CFTR RYR2

2.13e-047652int:SORCS1
GeneFamilyCalcium voltage-gated channel subunits

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F

2.77e-1026626253
GeneFamilyCorticotropin releasing hormone receptors

CRHR1 CRHR2

1.16e-052622266
GeneFamilyOlfactory receptors, family 6

OR6B3 OR6N2 OR6C1 OR6B2

2.78e-0551624153
GeneFamilyRyanodine receptors|Protein phosphatase 1 regulatory subunits

RYR1 RYR2

3.46e-053622287
GeneFamilyCation channels sperm associated

CATSPER2 CATSPER4

2.40e-047622186
GeneFamilySodium voltage-gated channel alpha subunits

SCN3A SCN5A

4.10e-0496221203
GeneFamilyCD molecules|Tetraspanins

TSPAN6 TSPAN1

5.71e-0333622768
CoexpressionWEBER_METHYLATED_HCP_IN_FIBROBLAST_DN

TPTE CATSPER2 SPACA1 ADAM30

5.63e-0643714M16646
CoexpressionWEBER_METHYLATED_HCP_IN_SPERM_UP

TPTE CATSPER2 SPACA1

2.10e-0520713M1506
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_500

CACNA1B CACNA1E SLC9A9 RYR2

9.44e-0641694gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k4_500
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3 RYR2

2.42e-081897272a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3 RYR2

2.60e-08191727b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3 RYR2

2.69e-081927273d0cb19f037f604253d7d728689aeaa94251e92b
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3 RYR2

2.69e-08192727deeecd26972241846b4cb998edf0c7a87ff0c4df
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 KALRN FAT3 RYR2

2.89e-08194727011e14d9ed1393275f892060e7708ffadcd0767f
ToppCellLPS-antiTNF-Stromal_mesenchymal|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3 RYR2

2.89e-081947276e13549f697f7478b34fe71f7dd9d63c5d3db22e
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A CACNA1B CACNA1C CACNA1D KALRN SCN3A RYR2

3.32e-08198727c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A CACNA1B CACNA1C CACNA1D KALRN SCN3A RYR2

3.32e-081987276d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 KALRN FAT3

3.32e-0819872717dc055e2a289496d9c5cdbf3297bdf906dc6d22
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1A CACNA1B CACNA1C CACNA1D KALRN SCN3A RYR2

3.32e-081987274ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCellFetal_29-31_weeks-Mesenchymal|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 KALRN FAT3 RYR2

3.32e-0819872721cf4d81386761d09d0f6829c01c198e5524176d
ToppCellNeuronal|World / cells hierarchy compared to all cells using T-Statistic

CACNA1A CACNA1B CACNA1C CACNA1D KALRN SCN3A RYR2

3.56e-0820072748d801219bc771d6c7e151dc88ca4c179988de85
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3 RYR2

3.56e-08200727cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3 RYR2

3.56e-08200727311fab076f2ceb258e3970eb21e39344b894042a
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

4.89e-071817269ede19228ba5c0668a9c06c915510b95585216ef
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F KALRN FAT3 CFTR PKD1L2 RYR2

5.38e-071847262cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F KALRN FAT3 CFTR PKD1L2 RYR2

5.38e-07184726ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F KALRN FAT3 CFTR PKD1L2 RYR2

5.38e-071847262b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

5.92e-0718772692d468dde81125d51daf7abd4703741abe1ab91c
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

6.30e-07189726a153b83314cf52808f685296cff8c95af3f4983d
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

6.50e-071907263a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

6.50e-07190726841cd55861b43578d704418b9bc0af2e8b88323a
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

6.70e-071917266688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

6.90e-071927266f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ATP13A3 ACVR1B GRINA EMP1 PTAFR CD163

6.90e-07192726f14ee74ac3275601749a23c5efe39c2413a62e1a
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

6.90e-0719272699ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

6.90e-07192726dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A3 ACVR1B GRINA EMP1 PTAFR CD163

6.90e-071927260219093e7921a0db78053aee13ec480b520f5662
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B CACNA1E KALRN FAT3 SCN3A KCNH3

7.12e-07193726461919ab422bc9d1fcff7a3a4757c75239041d7e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B CACNA1E KALRN FAT3 SCN3A KCNH3

7.12e-071937260dd810ad900d3e586551622b2c1de39d76fd6a7f
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.12e-0719372699525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.12e-07193726b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D231|Adult / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.12e-07193726ef2f456c094e6e3c6ee81e0668c953cb8d0e1c0a
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

7.12e-07193726fb28717fadd06c3840636d25409ce80c9254bd34
ToppCellMesenchymal-matrix_fibroblast_1_cell|World / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.12e-07193726acad568621ed677031797b8c2e34dafea798d681
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.34e-07194726e93de9428c986b8943fc169258847c650cfab0e5
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

7.34e-0719472660622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 FAT3 EMP1 RYR2

7.34e-0719472635f132cc38ac133be01834ed0946188aa0757eb4
ToppCellLPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

7.34e-0719472689b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1B CACNA1E KALRN FAT3 SCN3A KCNH3

7.56e-07195726ffbab350e67d9c4b66c0ab84550daec8b8139a27
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell|Adult / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.56e-0719572661c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCellCOVID-19-Fibroblasts-Alveolar_FB|COVID-19 / group, cell type (main and fine annotations)

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.56e-07195726603050beeb33c331d4b2e3fa46cae3f3e0e4bdc7
ToppCellAdult-Mesenchymal-matrix_fibroblast_1_cell-D122|Adult / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.56e-07195726aa0add081881d349099d12efca5cdee098038d4e
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B CACNA1C CACNA1D KALRN SCN3A RYR2

7.79e-07196726676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D COL6A3 SLC9A9 ABCA6 KALRN FAT3

7.79e-071967261450cb69c5bf469e97c03bf1890f6f7c54165b8a
ToppCellChildren_(3_yrs)-Mesenchymal|Children_(3_yrs) / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.79e-07196726bc94909f9b2dc08a59eef1914148b69720569c8f
ToppCellnucseq-Mesenchymal-Fibroblastic|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

7.79e-071967267d8505dac15fa59935ccf592afc54b04c4c6554f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1D COL6A3 SLC9A9 ABCA6 KALRN FAT3

8.02e-0719772631a1852911bda38543916585fda34255fd62a134
ToppCellPCW_13-14-Mesenchymal|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

8.02e-0719772673a2085d2682d636726a5432d572ae2a3fbe1c3f
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

8.02e-071977260034bae02ee7fcfea520d453ca3c842ab6963b12
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature1_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CACNA1C CACNA1D COL6A3 SLC9A9 ABCA6 FAT3

8.02e-0719772611a4c417f035e554431a8f03be13b5eefa3530c0
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.26e-071987263ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellnucseq-Mesenchymal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.26e-071987268f52243ca8b9ba68a75ae411506a3a6de258eb97
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CACNA1B CACNA1C CACNA1D KALRN SCN3A RYR2

8.26e-071987260ff30edfd3c133a42e8cb96e1631a1143215f808
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.26e-07198726f1374f7a50244d59c766ac41f44c08c9117407d2
ToppCellMesenchymal|World / Lineage, Cell type, age group and donor

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.51e-071997264bac110c2b3609f6ee5d0e3275da0824a6240270
ToppCellcellseq-Mesenchymal-Fibroblastic-Fibroblastic_2|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.51e-0719972666a79732caf2f04c09b4d9832377aa01ca477677
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.76e-07200726e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellParenchymal-10x5prime-Stromal-Fibroblastic-Fibro_alveolar|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.76e-072007268c62f05c6042f24287a73fbdf80ff4a56f7ff403
ToppCellParenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.76e-07200726aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.76e-07200726a510deaada669e690329183e18df02870bd204b3
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.76e-07200726cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.76e-0720072634f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellLung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CACNA1C CACNA1D COL6A3 ABCA6 FAT3 RYR2

8.76e-07200726dd4228cbed8a4395166a6332e08d44d88bebe3b9
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1_Progenitor|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1F ATG9B GCGR VAMP8 AQP4

2.99e-06138725615822e542f12aa83df1561e262b8d72bdefc60e
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1F ATP6V0A4 ADGRE4P PKD1L2 AQP4

4.96e-061537258cc2667213bfac37545bb63181e88ef1f1834413
ToppCellfacs-Lung-18m-Hematologic-myeloid-leukocyte-proliferating_myeloid_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1F ATP6V0A4 ADGRE4P PKD1L2 AQP4

4.96e-06153725596bb7cfd1c713708ce73df30d890a0233eae7f7
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

CACNA1A CACNA1B FAT3 RYR1 RYR2

5.98e-061597255335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellfacs-Lung-EPCAM-18m-Hematologic-Proliferating_Immune|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ATP6V0A4 ADGRE4P PKD1L2 AQP4

6.17e-061607257217730ae14840b935b3bf9aa49becbcbcd8a682
ToppCellRV-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNA1A CACNA1C KALRN FAT3 SCN3A

6.17e-0616072529c9b4770d0e73d59cffc7937b179484c76b6dcc
ToppCellfacs-Lung-EPCAM-18m-Hematologic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ATP6V0A4 ADGRE4P PKD1L2 AQP4

6.17e-06160725317ef81460c1a31b51119a6309b11be6a8d4ea3e
ToppCellfacs-Lung-EPCAM-18m-Hematologic-leukocyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1F ATP6V0A4 ADGRE4P PKD1L2 AQP4

6.17e-06160725e6191240c93da34fc4431a35ef496edf323cb41e
ToppCellRV-13._Vascular_Smooth_Muscle|RV / Chamber and Cluster_Paper

CACNA1A CACNA1C KALRN FAT3 SCN3A

6.36e-0616172547b3b7662cbb671ccc086dc0a0cabd65f63eb5a1
ToppCellcontrol-Epithelial-Ionocyte|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FAT3 DHCR7 CFTR ATP6V0A4 SCNN1G

7.16e-061657255cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCellPCW_07-8.5-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CRTAM GPR141 PTAFR VAMP8 CD163

7.37e-06166725f03f78cae6272c89618c0bda032ce45c4fc96baa
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Lymphoid_DC|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CACNA1E CACNA1F CD40 GCGR KCNH3

7.59e-061677258b223333c0c7a85b5a1af6f2f5b12ee0d94357f6
ToppCellcontrol-Epithelial-Ionocyte|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FAT3 DHCR7 CFTR ATP6V0A4 SCNN1G

7.82e-06168725327b02f19f4a8607c033203824fdc60a1254331f
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD164L2 KALRN ATP6V0A4 GCGR TSPAN1

8.76e-06172725bc1b889ac5e07b8324ae5837eca911f9c865e959
ToppCellfacs-Kidney-nan-18m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD164L2 KALRN ATP6V0A4 GCGR TSPAN1

8.76e-06172725ba70b6110b70afb1870e8dcaf58c507b8c7d918e
ToppCellCOVID-19-kidney-CD-IC-A|COVID-19 / Disease (COVID-19 only), tissue and cell type

CACNA1D CALCR CFTR ATP6V0A4 GCGR

9.79e-0617672545028197364c64e93e3ffe86aff773d47a477d49
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CACNA1C CACNA1D ABCA6 FAT3 RYR2

1.09e-0518072508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte-Ionocyte_L.0.7.0.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC9C1 FAT3 CFTR ATP6V0A4 SCNN1G

1.09e-051807255286e66ff6b7154390b3e9c189704a71d56bc89c
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte-Ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC9C1 FAT3 CFTR ATP6V0A4 SCNN1G

1.09e-051807252b6b295b5c21b829828afae9ab4c3eb9233f6f45
ToppCell5'-Parenchyma_lung-Epithelial-Neuro-endocrine/ionocytic-ionocyte|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC9C1 FAT3 CFTR ATP6V0A4 SCNN1G

1.09e-05180725bf587387145a2b5e83766fbccf76eecc6d5e8241
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

SLC9C1 CFTR ATP6V0A4 SCNN1G CHST3

1.12e-051817254a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D CALCR ATP6V0A4 PTAFR ITPR3

1.12e-0518172522363c5835dd6cef8f895ab9362e0837d92b15b1
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

CACNA1A CACNA1C KALRN FAT3 SCN3A

1.18e-05183725818fd886e0188091310825f9145fa53328f2c979
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ATP13A3 GRINA EMP1 PTAFR CD163

1.18e-051837254763df29c888d47c22076803b054f06b4cc29368
ToppCellPBMC-Control-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ATP13A3 GRINA EMP1 PTAFR CD163

1.18e-05183725fcb0f755382d88fb207fc2322cd224c09c6e2ea6
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

CACNA1A CACNA1C KALRN FAT3 SCN3A

1.18e-05183725cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellcritical-Epithelial-Ionocyte|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

FAT3 DHCR7 CFTR ATP6V0A4 SCNN1G

1.21e-0518472558d36577eff814d46d72f031f3533d71549e3d6e
ToppCellPND01-03-samps-Epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CFTR ATP6V0A4 SCNN1G VAMP8 TSPAN1

1.25e-051857252b854df79cfe2cb4d2f9c2938a066e0aa3649325
ToppCellChildren_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

SLC9A9 CALCR ABCA6 CD163 RYR1

1.25e-051857258207f9eff113eed429e961748c6b17d672a13b33
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CACNA1A CACNA1E KALRN RYR2 KCNH3

1.28e-051867257278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCellPND01-03-samps-Epithelial-Alveolar_epithelial|PND01-03-samps / Age Group, Lineage, Cell class and subclass

CFTR ATP6V0A4 SCNN1G VAMP8 TSPAN1

1.31e-0518772523fe3cdd6cc9b067086a8392d104186d300298ea
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

CACNA1C COL6A3 ABCA6 FAT3 RYR2

1.31e-05187725bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

CACNA1C KALRN FAT3 SCN3A RYR2

1.35e-0518872534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D CALCR SCN3A ATP6V0A4 GCGR

1.35e-05188725bc089cd73d283ed7d2ecbb3936673b4edc89f666
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CACNA1D CALCR SCN3A ATP6V0A4 GCGR

1.35e-05188725eec3d353e51358db4c7621265ee0fdd4298e5b0e
ToppCellCOVID-19-Epithelial-Ionocytes|COVID-19 / Condition, Lineage and Cell class

SLC9C1 CFTR ATP6V0A4 SCNN1G CHST3

1.35e-05188725a581cb9528d0febbf3addbb4f6bc140f91a584e6
ComputationalIon channels.

TPTE AQP4 RYR1 RYR2

1.68e-0470434MODULE_316
DrugCinildipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CALCR CRTAM RYR1 RYR2 ITPR3

1.61e-17567111CID000002752
Druglamotrigine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCN3A SCN5A SCNN1G GRINA RYR1 RYR2 ITPR3

3.54e-171167113CID000003878
DrugCNS 1145

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

5.99e-1633719CID000190902
DrugIHC-64

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

5.99e-1633719CID000162753
DrugIAA-94

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CFTR RYR1 RYR2 ITPR3

3.57e-15617110CID000003667
Drugbepridil

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCN3A SCN5A SCNN1G RYR1 RYR2 ITPR3

4.69e-151267112CID000002351
Druggabapentin

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCN3A SCN5A SCNN1G GRINA RYR1 RYR2 ITPR3

5.21e-151697113CID000003446
Drugriluzole

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCN3A SCN5A SCNN1G GRINA RYR1 RYR2 ITPR3

7.62e-151747113CID000005070
DrugNSC7524

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCN3A SCN5A SCNN1G GRINA RYR1 RYR2 ITPR3

1.37e-141827113CID000005657
Drugisradipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCN3A SCNN1G RYR1 RYR2 ITPR3

1.37e-141007111CID000003784
Drugprocaine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CFTR SCN3A SCNN1G RYR1 RYR2 ITPR3

4.99e-141537112CID000004914
Drugphenytoin

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F COL6A3 SCN3A SCN5A SCNN1G RYR1 RYR2 ITPR3

1.50e-132197113CID000001775
Drugnilvadipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

2.15e-1360719CID000004494
Druglercanidipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

3.41e-1363719CID000065866
Druggallopamil

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

6.10e-1367719CID000001234
DrugAC1L2AC7

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

8.05e-1369719CID000068733
DrugCAS 298-57-7

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

1.37e-1273719CID000002761
Drugethosuximide

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

1.55e-1274719CID000003291
Drugverapamil

EPHB6 CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F ABCA6 CFTR SCN3A SCN5A SCNN1G RYR1 RYR2 ITPR3

1.79e-124907116CID000002520
Drugnisoldipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

2.53e-1278719CID000004499
DrugN-cyclopentyl-N-cyclobutylformamide

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

2.85e-1279719CID005287890
Drugfelodipine

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F CFTR RYR1 RYR2 ITPR3

4.73e-121697111CID000003333
DrugVerapamil

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1F SCN5A

5.79e-1216716DB00661
Drugmanidipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

1.57e-1195719CID000004008
DrugNSC759576

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F GCGR AQP4 RYR1 RYR2 ITPR3

1.79e-111917111CID000003075
Drugisotetrandrine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

1.90e-1197719CID000005422
Drugnitrendipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

2.08e-1198719CID000004507
Drugnimodipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F GRINA RYR1 RYR2 ITPR3

2.66e-111457110CID000004497
DrugDantrolene-13C3

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F GRINA RYR1 RYR2 ITPR3

2.66e-111457110CID000002951
Drugloperamide

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

3.91e-11105719CID000003954
DrugAC1NBU2S

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

1.04e-10117719CID004473765
DrugAC1L1DXE

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F WDR7 CFTR GRINA RYR1 RYR2 ITPR3

1.35e-102997112CID000002548
Druglavendustin A

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CFTR RYR1 RYR2 ITPR3

1.36e-101717110CID000003894
Drugpapaverine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CFTR RYR1 RYR2 ITPR3

1.81e-101767110CID000004680
Drugpimozide

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

2.18e-10127719CID000016362
Drugaldosterone

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TAS2R1 DHCR7 CFTR SCNN1G RYR1 RYR2 ITPR3

2.64e-103977113CID000005839
Druglanthanum

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

4.03e-10136719CID000023926
Drugbaclofen

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F GRINA RYR1 RYR2 ITPR3

4.04e-101917110CID000002284
Drugdihydropyridine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCNN1G RYR1 RYR2 ITPR3

4.47e-101937110CID000104822
Drugnicardipine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

7.14e-10145719CID000004473
DrugBay K 8644

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

9.66e-10150719CID000002303
Drugpotassium

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SLC9A9 CFTR SCN3A ATP6V0A4 SCN5A SCNN1G GRINA AQP4 RYR1 RYR2 KCNH3 ITPR3

1.24e-0910087118CID000000813
DrugU46619

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F TMPO PTAFR RYR1 RYR2 ITPR3

1.28e-092857111CID000005618
DrugAC1L1TJF

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CRTAM

1.42e-0966717CID000003377
DrugBarium

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F KCNH3

2.66e-0972717ctd:D001464
DrugAC1L1KS5

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CRHR1 CRHR2 RYR1 RYR2 ITPR3

6.72e-093347111CID000005631
Drugcyclophorine

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F COL6A3 CD40 AQP4 RYR1 RYR2 ITPR3

7.46e-094267112CID000002909
DrugKW-3049

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1F

1.06e-0850716CID000002324
Drugmercury

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F CFTR CD40 AQP4 RYR1 RYR2 ITPR3

1.12e-085427113CID000023931
Druggadolinium

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

1.16e-08199719CID000023982
Druglindane

CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

2.71e-08154718CID000000727
Drugethanol

CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F SCN3A CD40 SCNN1G GCGR ACVR1B GRINA VAMP8 CRHR1 ITPR3

3.58e-088377115CID000000702
DrugCalcium

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F CFTR PTAFR RYR1 RYR2 ITPR3

3.74e-084937112ctd:D002118
Drug8-bromoguanosine 3',5'-cyclic monophosphate

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CFTR RYR1 RYR2 ITPR3

3.95e-083087110CID000001915
Drugpyraclofos

CACNA1A CACNA1B CACNA1C CACNA1D SCN5A SCNN1G KCNH3

4.04e-08106717CID000093460
Drug3-(1H-pyrrole-2-carboxylate

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E SCN5A RYR1 RYR2 ITPR3

4.53e-08233719CID000005114
Drughalothane

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

4.74e-083147110CID000003562
Drugmibefradil

CACNA1A CACNA1B CACNA1C CACNA1D SCN5A RYR1

4.82e-0864716CID000060662
Drugnifedipine

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F GRINA RYR1 RYR2 ITPR3

6.21e-084157111CID000004485
DrugBAPTA

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CFTR GRINA RYR1 RYR2 ITPR3

6.35e-083247110CID000104751
DrugAC1L1JG6

CACNA1A CACNA1B CACNA1C CACNA1D

8.49e-0814714CID000005026
Drugflecainide

SCN3A SCN5A CRTAM SCNN1G RYR1 RYR2

9.05e-0871716CID000003355
Drugpropranolol

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F SCN5A RYR1 RYR2 ITPR3

9.75e-084347111CID000004946
Drugfluo-3

CACNA1C CACNA1D TMPO GRINA RYR1 RYR2 ITPR3

1.07e-07122717CID000104978
Drugbutamben

CACNA1A CACNA1B CACNA1C CACNA1E

1.15e-0715714CID000002482
DrugFPL 64176

CACNA1C CACNA1D RYR1 RYR2

1.15e-0715714CID000003423
DrugAC 110

CACNA1A CACNA1B CACNA1E

1.16e-074713CID000022860
Drugisoproterenol

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1F CFTR SCN3A SCN5A SCNN1G GCGR AQP4 RYR1 RYR2

1.31e-076697113CID000003779
Drugamlodipine

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F

1.33e-07126717CID000002162
Drugcaffeine

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F TAS2R1 GRINA RYR1 RYR2 ITPR3

1.55e-075627112CID000002519
Drugguanosine 3',5'-cyclic monophosphoric acid

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CFTR TMPO GRINA RYR1 RYR2 ITPR3

2.05e-075777112CID000000295
Drugglutamate

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CFTR CD40 SCNN1G IFT122 GRINA AQP4 RYR1 RYR2 ITPR3

2.18e-079627115CID000000611
Druggamma-aminobutyric acid

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F CFTR GRINA RYR1 RYR2 ITPR3

2.36e-074747111CID000000119
DrugIsradipine

CYP1A1 CACNA1D CACNA1E CACNA1F

2.57e-0718714ctd:D017275
DrugGTP[S]

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CFTR SCN3A SCNN1G GCGR CRHR1 RYR1 ITPR3

2.65e-075917112CID000001764
Drugvalproate

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCNN1G RYR1 RYR2 ITPR3

2.85e-073817110CID000003121
Drugisovalerate

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E SCN5A RYR1

3.16e-07143717CID000010430
Drugpranidipine

CACNA1A CACNA1B CYP1A1 CACNA1E

3.25e-0719714CID006436048
Drug3,4-dihydroquinazoline

CACNA1A CACNA1B CACNA1E

5.77e-076713CID000583065
Drugalpha-sialylcholesterol

CACNA1A CACNA1B CACNA1E

5.77e-076713CID000133976
DrugAC1L1GTT

CACNA1B CACNA1C CACNA1D GRINA CRHR2 RYR1 RYR2 ITPR3

6.52e-07233718CID000003837
DrugN-methyl-DL-aspartic acid

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F SCNN1G GRINA CRHR1 RYR1 RYR2 ITPR3

7.89e-076557112CID000004376
DrugAmlodipine

CACNA1B CACNA1C CACNA1D

1.01e-067713DB00381
Drug[[(2R,3S,4R)-5-(2-amino-6-oxo-3H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl] [(2R,3S,4R,5R)-3,4,5-trihydroxyoxolan-2-yl]methyl hydrogen phosphate

RYR1 RYR2 ITPR3

1.01e-067713CID009547999
DrugAPMPA

CACNA1A CACNA1B CACNA1E

1.01e-067713CID000512300
DrugBr2BAPTA

RYR1 RYR2 ITPR3

1.01e-067713CID003081001
DrugK-Cl

EPHB6 CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E SLC9A9 CFTR CD40 RYR1 RYR2

1.37e-065677111CID000004873
Drug4-AP

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E SCNN1G GRINA KCNH3

1.40e-06258718CID000001727
Drugisobutanol

CACNA1A CACNA1B CACNA1C CACNA1D PTAFR

1.44e-0662715CID000006560
DrugEGTA-AM

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E

1.44e-0662715CID000121907
DrugmAHP

CACNA1A CACNA1B CACNA1D CACNA1E

1.44e-0627714CID000220531
Drugnoradrealine

CACNA1A CACNA1B CYP1A1 CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 TSPAN1 ITPR3

1.57e-065757111CID000000951
Drughydride

CACNA1B CYP1A1 CACNA1E SLC9A9 DHCR7 CFTR ATP6V0A4 SCNN1G GRINA RFT1 HVCN1 RYR1 ITPR3

1.61e-068357113CID000000783
DrugNiCl2

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E SCN5A

1.95e-06119716CID000024385
DrugCinnarizine

CACNA1C CACNA1D CACNA1F

2.41e-069713DB00568
DrugNimodipine

CACNA1C CACNA1D CACNA1F

2.41e-069713DB00393
DrugSulfachloropyridazine [80-32-0]; Up 200; 14uM; PC3; HT_HG-U133A

CYP1A1 CACNA1D TAS2R1 KALRN CD40 AQP4 CRHR2

2.72e-061977173769_UP
DrugC070379

CACNA1B CACNA1E SCNN1G GRINA RYR1 RYR2 ITPR3

2.91e-06199717CID003034747
Drugcobalt-60

CACNA1A CACNA1B CACNA1C CACNA1D CACNA1E CACNA1F RYR1 RYR2 ITPR3

3.38e-06390719CID000061492
DrugPCB 95

CYP1A1 RYR1 RYR2

3.43e-0610713CID000038012
Diseasefamilial hemiplegic migraine 1 (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

1.28e-083703DOID:0111181 (implicated_via_orthology)
Diseasemigraine (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

5.11e-084703DOID:6364 (implicated_via_orthology)
DiseaseTimothy syndrome (implicated_via_orthology)

CACNA1C CACNA1D CACNA1F

5.11e-084703DOID:0060173 (implicated_via_orthology)
Diseasehereditary ataxia (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E

4.44e-077703DOID:0050951 (implicated_via_orthology)
DiseaseLong QT Syndrome

CYP1A1 SCN5A RYR2

2.08e-0611703C0023976
Diseaseepilepsy (implicated_via_orthology)

CACNA1A CACNA1B CACNA1E KALRN SCN3A SCN5A

2.54e-06163706DOID:1826 (implicated_via_orthology)
Diseasecongenital myopathy 1A (implicated_via_orthology)

RYR1 RYR2

1.66e-053702DOID:3529 (implicated_via_orthology)
Diseasemalignant hyperthermia (implicated_via_orthology)

RYR1 RYR2

1.66e-053702DOID:8545 (implicated_via_orthology)
DiseaseArrhythmogenic Right Ventricular Dysplasia

SCN5A RYR2

1.66e-053702C0349788
Diseasefunctional colonic disease (biomarker_via_orthology)

CRHR1 CRHR2

1.66e-053702DOID:3877 (biomarker_via_orthology)
DiseaseAnhedonia

CACNA1C CRHR1 CRHR2

2.50e-0524703C0178417
DiseaseIdiopathic bronchiectasis

CFTR SCNN1G

3.32e-054702cv:C0339985
DiseaseBronchiectasis

CFTR SCNN1G

3.32e-054702cv:C0006267
DiseaseIdiopathic bronchiectasis

CFTR SCNN1G

3.32e-054702C0339985
Diseaselongitudinal BMI measurement

CACNA1E TAS2R1 CALCR ADGRE4P

4.42e-0582704EFO_0005937
DiseaseChronic obstructive pulmonary disease

CFTR SCNN1G

8.27e-056702cv:C0024117
DiseaseSick Sinus Syndrome

CACNA1D SCN5A

8.27e-056702C0037052
Diseaseprimary pulmonary hypertension (is_implicated_in)

ATP13A3 RYR1

8.27e-056702DOID:14557 (is_implicated_in)
DiseaseDuchenne muscular dystrophy (implicated_via_orthology)

CACNA1C CACNA1D CACNA1F

8.63e-0536703DOID:11723 (implicated_via_orthology)
DiseaseEarly Pregnancy Loss

CYP1A1 COL6A3 EMP1 CD163

1.34e-04109704C3830362
DiseaseSpontaneous abortion

CYP1A1 COL6A3 EMP1 CD163

1.34e-04109704C0000786
DiseaseMiscarriage

CYP1A1 COL6A3 EMP1 CD163

1.34e-04109704C4552766
DiseaseAbortion, Tubal

CYP1A1 COL6A3 EMP1 CD163

1.34e-04109704C0000822
DiseaseBipolar Disorder

CACNA1A CACNA1B CACNA1C CACNA1D MPPE1 CRHR1 CRHR2

1.38e-04477707C0005586
DiseaseBrugada syndrome

CACNA1C SCN5A

1.54e-048702cv:C1142166
Diseaseirritable bowel syndrome (biomarker_via_orthology)

CRHR1 CRHR2

1.54e-048702DOID:9778 (biomarker_via_orthology)
DiseaseAnxiety States, Neurotic

CACNA1C CRHR1 CRHR2

1.58e-0444703C0376280
DiseaseAnxiety neurosis (finding)

CACNA1C CRHR1 CRHR2

1.58e-0444703C1279420
DiseaseAnxiety Disorders

CACNA1C CRHR1 CRHR2

1.58e-0444703C0003469
DiseasePulmonary Cystic Fibrosis

CFTR SCNN1G

1.98e-049702C0392164
DiseaseFibrocystic Disease of Pancreas

CFTR SCNN1G

1.98e-049702C1527396
Diseaselifestyle measurement, systolic blood pressure

SLC9A9 KALRN

1.98e-049702EFO_0006335, EFO_0010724
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN3A SCN5A

2.47e-0410702DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN3A SCN5A

2.47e-0410702DOID:0080422 (implicated_via_orthology)
DiseaseTachycardia, Ventricular

SCN5A RYR2

3.01e-0411702C0042514
DiseaseCystic Fibrosis

CFTR SCNN1G

3.01e-0411702C0010674
Diseaseaortic measurement

COL6A3 KALRN RTP4 CRHR2 RYR2

3.30e-04251705EFO_0020865
DiseaseHypertrophic Cardiomyopathy

CACNA1C TMPO RYR2

3.41e-0457703C0007194
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN3A SCN5A

3.61e-0412702DOID:0060170 (implicated_via_orthology)
DiseaseSudden infant death syndrome

SCN5A AQP4

3.61e-0412702C0038644
Diseasecolitis (implicated_via_orthology)

CD40 CRHR2

4.25e-0413702DOID:0060180 (implicated_via_orthology)
Diseasechronic obstructive pulmonary disease (is_implicated_in)

CYP1A1 CFTR CRHR1

4.58e-0463703DOID:3083 (is_implicated_in)
Diseaseasthma (is_implicated_in)

CFTR CD40 CRHR1 CRHR2

5.38e-04157704DOID:2841 (is_implicated_in)
DiseaseMood Disorders

CACNA1C CACNA1D CRHR1 CRHR2

6.94e-04168704C0525045
Diseaseischemia (implicated_via_orthology)

SCNN1G CRHR2

7.37e-0417702DOID:326 (implicated_via_orthology)
DiseaseAnorexia

CRHR1 CRHR2

8.28e-0418702C0003123
Diseasepulmonary hypertension (biomarker_via_orthology)

CYP1A1 RYR1 RYR2

9.22e-0480703DOID:6432 (biomarker_via_orthology)
DiseaseHypertensive disease

CYP1A1 CACNA1C SCNN1G CRHR2

1.10e-03190704C0020538
DiseaseDystonia

CACNA1A CACNA1E COL6A3

1.14e-0386703C0013421
DiseaseBronchiectasis

CFTR SCNN1G

1.24e-0322702C0006267
Diseasetrans fatty acid measurement, trans/trans-18:2 fatty acid measurement

CACNA1D OR6N2

1.48e-0324702EFO_0006821, EFO_0006826
DiseaseBrugada Syndrome (disorder)

CACNA1C SCN5A

1.48e-0324702C1142166
Diseaseuveitis (biomarker_via_orthology)

AQP4 CD163

1.61e-0325702DOID:13141 (biomarker_via_orthology)
DiseaseInvolutional paraphrenia

CACNA1C CRHR1

1.61e-0325702C1571983
DiseasePsychosis, Involutional

CACNA1C CRHR1

1.61e-0325702C1571984
DiseaseInvolutional Depression

CACNA1C CRHR1

1.61e-0325702C0011574
DiseaseEndogenous Hyperinsulinism

CD40 CD163

1.74e-0326702C1257963
DiseaseExogenous Hyperinsulinism

CD40 CD163

1.74e-0326702C1257964
DiseaseCompensatory Hyperinsulinemia

CD40 CD163

1.74e-0326702C1257965
DiseaseBradycardia

CYP1A1 CACNA1D

1.74e-0326702C0428977
Diseasewhite matter integrity, age at assessment

WDR7 TSPAN1

1.74e-0326702EFO_0004641, EFO_0008007
Diseasecystic fibrosis (is_implicated_in)

CYP1A1 CFTR

1.87e-0327702DOID:1485 (is_implicated_in)
DiseaseHyperinsulinism

CD40 CD163

2.02e-0328702C0020459
DiseaseCiliopathies

CFTR TMEM138 SCNN1G

2.30e-03110703C4277690
DiseaseHyperglycemia, Postprandial

CD40 CD163

2.31e-0330702C1855520
DiseaseHyperglycemia

CD40 CD163

2.31e-0330702C0020456

Protein segments in the cluster

PeptideGeneStartEntry
CVIVFIIILFIVLFA

VAMP8

81

Q9BV40
FVNIFVALIIITFQE

CACNA1A

1501

O00555
LVELIITFQLVFTIF

AQP4

161

P55087
IFDFIQLLLIVIGAI

CFTR

991

P13569
KNFIIFLVFLNTIIL

CATSPER2

111

Q96P56
FIIVFILLLRFFINE

CATSPER4

161

Q7RTX7
PFFFVNIFVALIIIT

CACNA1E

1411

Q15878
VNFFFLLNIVRVLVT

CALCR

311

P30988
FQFLFIDLAIILVVV

ATP13A3

966

Q9H7F0
FLLFLIIIIVFLVIN

ACVR1B

136

P36896
QALVDVSFFILILLL

ABCA6

1061

Q8N139
AVIILINLVFYFQVL

ADGRE4P

346

Q86SQ3
VLVNVLQAIYVIDFF

DHCR7

271

Q9UBM7
FFVNIFVALIIITFQ

CACNA1B

1406

Q00975
IVQLFFFILLGVTEF

OR6C1

96

Q96RD1
QVLFRLITFVLNAFI

RFT1

21

Q96AA3
EVFLFLAILLQRVEF

CYP1A1

466

P04798
VIFVIAVAVILLVFQ

GPR141

186

Q7Z602
FFIVIIIVLNLIFGV

ITPR3

2501

Q14573
LAVEVLFILDIVLNF

KCNH3

266

Q9ULD8
LDFIIVVVGLFSVLL

CACNA1F

166

O60840
SIIFCVIALLVFVFQ

EMP1

71

P54849
QILKIFVDNLFAIVL

IFT122

496

Q9HBG6
VVLFIFAILCIFIRN

GRINA

291

Q7Z429
VVVVVSFILDIVLLF

HVCN1

176

Q96D96
EVFLFNDLLVVTKIF

IQSEC2

996

Q5JU85
LIAVVFAVLLFCEFL

MPPE1

26

Q53F39
ILRFPVFLAILINFF

GCGR

306

P47871
VFLAILINFFIFVRI

GCGR

311

P47871
LINFFIFVRIVQLLV

GCGR

316

P47871
RVFLFEQIVIFSELL

KALRN

2146

O60229
LLINFVFLFNIVRIL

CRHR2

276

Q13324
KILLFVVVAVFLFLV

TMPO

416

P42167
VLNLFISVILVAFSE

PKD1L2

2386

Q7Z442
ILVDFAINAFIILIT

OR6N2

196

Q8NGY6
LILLILSVVFVFFRQ

ADAM30

696

Q9UKF2
SLVFVLLFIFVKRQI

C1orf43

21

Q9BWL3
FLIIFTVEAFLKVIA

CACNA1C

166

Q13936
IVNDTIFTNLILFFI

CACNA1C

896

Q13936
FDFLIVIGSIIDVIL

CACNA1C

1306

Q13936
QIIHFVLFVVFSLVI

C5orf60

36

A6NFR6
FLIFILFIIVQLFIM

CRTAM

296

O95727
VNFAVILDFLVNLLE

COL6A3

256

P12111
VLFVIFILVVLFIVF

FAT3

4161

Q8TDW7
ILVLLINFIFLFNIV

CRHR1

306

P34998
ILLEDVFQLGQFIFI

ATG9B

211

Q674R7
VVLVLSLQAVAFFVL

CD164L2

146

Q6UWJ8
ILGVVLLAIFVALFF

CD163

1056

Q86VB7
VIEIIEVFFIDFFSI

SCNN1G

546

P51170
GVIICVFIIFLLIFI

SPACA1

226

Q9HBV2
VFIIFLLIFIIINWA

SPACA1

231

Q9HBV2
FIIILGVANLIVQFF

SLC38A9

546

Q8NBW4
FFFFVIVILLAIIQG

RYR1

4921

P21817
FFFVIVILLAIIQGL

RYR2

4851

Q92736
VEISIFFIIYIIIVA

CACNA1D

1126

Q01668
ELVDFILAFIILVFP

OR6B2

196

Q6IFH4
GLFVVSFFVLNLVLI

OR52J3

201

Q8NH60
VQRVLFVVFLLIYVV

OR4C3

21

Q8NH37
LNICVFILLLVFIVV

RTP4

226

Q96DX8
AVELLVFNFLLILTI

SLC9A9

21

Q8IVB4
EVIVFIKVVQFFRIL

SLC9C1

706

Q4G0N8
FLVFLIILFCNLVII

PTAFR

196

P25105
FLLLAAITVLAVVFQ

EPHB6

606

O15197
NLTLVLAIIVFIFAV

SCN5A

841

Q14524
INLVFIVLFTGEFVL

SCN3A

1561

Q9NY46
IFFVVFLIVYLVNVV

OR5AR1

26

Q8NGP9
ELVDFILAFIILVFP

OR6B3

196

Q8NGW1
LVVVIVASFFILKNF

SSR3

146

Q9UNL2
LFLVFVVIVFVFIEK

CHST3

26

Q7LGC8
IFLQLFIFYVNVIVI

TAS2R1

56

Q9NYW7
LFIIQDIAVLFNIII

TMEM138

41

Q9NPI0
IVILLLVDVVYIFFD

TPTE

166

P56180
FLTLVFLVELVAAIV

TSPAN6

96

O43657
NLLQAVFFVLFVLSV

TEX50

81

A0A1B0GTY4
IFAVFAVLTVAILLI

ATP6V0A4

781

Q9HBG4
LFFDVEALIIQLLTE

WDR7

691

Q9Y4E6
IFGILFAILLVLVFI

CD40

201

P25942
FILLLIFIAEVAAAV

TSPAN1

91

O60635