Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpeptide lactyltransferase (CoA-dependent) activity

CREBBP EP300

3.34e-062372GO:0120300
GeneOntologyMolecularFunctionhistone H3K27 acetyltransferase activity

CREBBP EP300

3.34e-062372GO:0044017
GeneOntologyMolecularFunctionhistone H3K18 acetyltransferase activity

CREBBP EP300

1.00e-053372GO:0043993
GeneOntologyMolecularFunctionSMAD binding

SMURF1 CREBBP EP300 SMAD5

1.90e-0586374GO:0046332
GeneOntologyMolecularFunctiontranscription coregulator binding

TRERF1 HNF1B CREBBP EP300

1.28e-04140374GO:0001221
GeneOntologyMolecularFunctiontranscription coactivator binding

TRERF1 CREBBP EP300

1.36e-0454373GO:0001223
GeneOntologyMolecularFunctionRNA polymerase II CTD heptapeptide repeat kinase activity

CCNK BRD4

1.49e-0410372GO:0008353
GeneOntologyMolecularFunctiontranscription coactivator activity

TRERF1 CREBBP EP300 BRD4 TOX3

2.28e-04303375GO:0003713
GeneOntologyMolecularFunctionchromatin DNA binding

TOX CREBBP EP300 TOX3

2.51e-04167374GO:0031490
GeneOntologyMolecularFunctionhistone H3 acetyltransferase activity

CREBBP EP300

3.46e-0415372GO:0010484
GeneOntologyMolecularFunctionchromatin binding

CHD7 TOX CREBBP MEF2C EP300 BRD4 TOX3

3.61e-04739377GO:0003682
GeneOntologyMolecularFunctionp53 binding

CREBBP EP300 BRD4

3.90e-0477373GO:0002039
GeneOntologyMolecularFunctionI-SMAD binding

SMURF1 SMAD5

4.46e-0417372GO:0070411
GeneOntologyMolecularFunctionacyltransferase activity

SMURF1 RNF38 RPGR CPT1B CBLL2 CREBBP EP300

4.80e-04775377GO:0016746
GeneOntologyMolecularFunctiontranscription coregulator activity

TRERF1 MED15 CREBBP EP300 BRD4 TOX3

5.35e-04562376GO:0003712
GeneOntologyMolecularFunctionperoxisome proliferator activated receptor binding

CREBBP EP300

6.86e-0421372GO:0042975
GeneOntologyMolecularFunctionRNA polymerase II CTD heptapeptide repeat modifying activity

CCNK BRD4

8.25e-0423372GO:0140994
GeneOntologyMolecularFunctionRNA polymerase II-specific DNA-binding transcription factor binding

TRERF1 CNOT1 CREBBP MEF2C EP300

9.75e-04417375GO:0061629
GeneOntologyMolecularFunctionRNA polymerase II transcription regulatory region sequence-specific DNA binding

ZNF384 HNF1B CHD7 USF3 ZFHX4 CREBBP MEF2C EP300 SMAD5

1.11e-031459379GO:0000977
GeneOntologyMolecularFunctionacetylation-dependent protein binding

EP300 BRD4

1.50e-0331372GO:0140033
GeneOntologyMolecularFunctionbHLH transcription factor binding

CREBBP EP300

2.14e-0337372GO:0043425
GeneOntologyMolecularFunctiontranscription factor binding

TRERF1 HNF1B CNOT1 CREBBP MEF2C EP300

2.41e-03753376GO:0008134
GeneOntologyMolecularFunctionmolecular adaptor activity

TRERF1 MED15 FEM1C CNOT1 CREBBP EP300 BRD4 TOX3

2.91e-031356378GO:0060090
GeneOntologyMolecularFunctionhistone acetyltransferase activity

CREBBP EP300

4.02e-0351372GO:0004402
GeneOntologyMolecularFunctionDNA-binding transcription factor binding

TRERF1 CNOT1 CREBBP MEF2C EP300

4.17e-03582375GO:0140297
GeneOntologyMolecularFunctionpeptide-lysine-N-acetyltransferase activity

CREBBP EP300

4.66e-0355372GO:0061733
GeneOntologyMolecularFunctionubiquitin protein ligase activity

SMURF1 RNF38 RPGR CBLL2

4.82e-03372374GO:0061630
GeneOntologyMolecularFunctionprotein-macromolecule adaptor activity

TRERF1 MED15 FEM1C CREBBP EP300 BRD4 TOX3

4.87e-031160377GO:0030674
GeneOntologyMolecularFunctionnuclear receptor binding

TRERF1 CNOT1 EP300

4.97e-03187373GO:0016922
GeneOntologyMolecularFunctionpeptide N-acetyltransferase activity

CREBBP EP300

5.53e-0360372GO:0034212
GeneOntologyMolecularFunctionubiquitin-like protein ligase activity

SMURF1 RNF38 RPGR CBLL2

6.11e-03398374GO:0061659
GeneOntologyMolecularFunctionmodification-dependent protein binding

EP300 BRD4 UBQLN3

6.50e-03206373GO:0140030
GeneOntologyMolecularFunctionbasal RNA polymerase II transcription machinery binding

CREBBP BRD4

6.65e-0366372GO:0001099
GeneOntologyMolecularFunctionbasal transcription machinery binding

CREBBP BRD4

6.65e-0366372GO:0001098
GeneOntologyMolecularFunctionRNA polymerase II cis-regulatory region sequence-specific DNA binding

ZNF384 HNF1B CHD7 ZFHX4 MEF2C EP300 SMAD5

7.10e-031244377GO:0000978
GeneOntologyMolecularFunctioncis-regulatory region sequence-specific DNA binding

ZNF384 HNF1B CHD7 ZFHX4 MEF2C EP300 SMAD5

7.96e-031271377GO:0000987
GeneOntologyMolecularFunctionN-acetyltransferase activity

CREBBP EP300

9.18e-0378372GO:0008080
GeneOntologyMolecularFunctionacyltransferase activity, transferring groups other than amino-acyl groups

CPT1B CREBBP EP300

9.64e-03238373GO:0016747
GeneOntologyMolecularFunctionpromoter-specific chromatin binding

CHD7 EP300

1.03e-0283372GO:1990841
GeneOntologyMolecularFunctiondamaged DNA binding

CREBBP EP300

1.06e-0284372GO:0003684
GeneOntologyMolecularFunctionubiquitin-protein transferase activity

SMURF1 RNF38 RPGR CBLL2

1.11e-02473374GO:0004842
GeneOntologyMolecularFunctionubiquitin-like protein transferase activity

SMURF1 RNF38 RPGR CBLL2

1.45e-02512374GO:0019787
GeneOntologyMolecularFunctionN-acyltransferase activity

CREBBP EP300

1.53e-02102372GO:0016410
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

PAXIP1 TRERF1 MED15 ZNF384 HNF1B CHD7 USF3 TOX CREBBP CCNK MEF2C EP300 BRD4 SMAD5 TOX3

5.68e-0913903715GO:0045944
GeneOntologyBiologicalProcesspositive regulation of leukocyte activation

PAXIP1 IL16 TOX MEF2C EP300 BRD4 HPS1

8.78e-06423377GO:0002696
GeneOntologyBiologicalProcesspositive regulation of cell activation

PAXIP1 IL16 TOX MEF2C EP300 BRD4 HPS1

1.29e-05449377GO:0050867
GeneOntologyBiologicalProcessN-terminal peptidyl-lysine acetylation

CREBBP EP300

1.87e-054372GO:0018076
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell lineage commitment

TOX EP300 BRD4

2.31e-0531373GO:0043373
GeneOntologyBiologicalProcessalpha-beta T cell lineage commitment

TOX EP300 BRD4

2.79e-0533373GO:0002363
GeneOntologyBiologicalProcesscell fate commitment

HNF1B TOX MEF2C EP300 BRD4 SMAD5

2.81e-05338376GO:0045165
GeneOntologyBiologicalProcessCD4-positive or CD8-positive, alpha-beta T cell lineage commitment

TOX EP300 BRD4

3.34e-0535373GO:0043369
GeneOntologyBiologicalProcessprotein-DNA complex organization

PAXIP1 MED15 HNF1B CHD7 TOX CREBBP EP300 EMSY BRD4

5.16e-05999379GO:0071824
GeneOntologyBiologicalProcesspositive regulation of lymphocyte activation

PAXIP1 TOX MEF2C EP300 BRD4 HPS1

5.80e-05385376GO:0051251
GeneOntologyBiologicalProcessT cell lineage commitment

TOX EP300 BRD4

5.81e-0542373GO:0002360
GeneOntologyBiologicalProcesspositive regulation of T-helper 17 cell lineage commitment

EP300 BRD4

8.71e-058372GO:2000330
GeneOntologyBiologicalProcessregulation of developmental growth

SMURF1 HNF1B CHD7 ATXN2 MEF2C EP300

9.49e-05421376GO:0048638
GeneOntologyBiologicalProcesspositive T cell selection

TOX EP300 BRD4

1.17e-0453373GO:0043368
GeneOntologyBiologicalProcesspositive regulation of transcription elongation by RNA polymerase II

MED15 CCNK BRD4

1.24e-0454373GO:0032968
GeneOntologyBiologicalProcessembryo development

HNF1B CHD7 STIL CNOT1 CREBBP CCNK MEF2C EP300 BRD4 SMAD5

1.60e-0414373710GO:0009790
GeneOntologyBiologicalProcesschordate embryonic development

HNF1B CHD7 STIL CNOT1 CCNK MEF2C EP300 BRD4

1.67e-04906378GO:0043009
GeneOntologyBiologicalProcessregulation of T-helper 17 cell lineage commitment

EP300 BRD4

1.70e-0411372GO:2000328
GeneOntologyBiologicalProcessdevelopmental growth

SMURF1 HNF1B CHD7 STIL ATXN2 MEF2C EP300 BRD4

1.73e-04911378GO:0048589
GeneOntologyBiologicalProcesspositive regulation of DNA-templated transcription, elongation

MED15 CCNK BRD4

1.87e-0462373GO:0032786
GeneOntologyBiologicalProcessface development

CHD7 CREBBP EP300

1.96e-0463373GO:0060324
GeneOntologyBiologicalProcessembryo development ending in birth or egg hatching

HNF1B CHD7 STIL CNOT1 CCNK MEF2C EP300 BRD4

1.98e-04929378GO:0009792
GeneOntologyBiologicalProcessregulation of leukocyte activation

PAXIP1 IL16 TOX MEF2C EP300 BRD4 HPS1

2.02e-04694377GO:0002694
GeneOntologyBiologicalProcessregulation of sarcomere organization

MEF2C EP300

2.41e-0413372GO:0060297
GeneOntologyBiologicalProcessT cell selection

TOX EP300 BRD4

2.57e-0469373GO:0045058
GeneOntologyBiologicalProcesspositive regulation of transcription initiation by RNA polymerase II

PAXIP1 MED15 HNF1B

2.68e-0470373GO:0060261
GeneOntologyBiologicalProcesspositive regulation of T-helper 17 cell differentiation

EP300 BRD4

2.81e-0414372GO:2000321
GeneOntologyBiologicalProcesscellular response to transforming growth factor beta stimulus

SMURF1 CREBBP MEF2C EP300 SMAD5

3.16e-04336375GO:0071560
GeneOntologyBiologicalProcesstranscription initiation at RNA polymerase II promoter

PAXIP1 MED15 HNF1B EP300

3.35e-04186374GO:0006367
GeneOntologyBiologicalProcessregulation of cell activation

PAXIP1 IL16 TOX MEF2C EP300 BRD4 HPS1

3.40e-04756377GO:0050865
GeneOntologyBiologicalProcessresponse to transforming growth factor beta

SMURF1 CREBBP MEF2C EP300 SMAD5

3.48e-04343375GO:0071559
GeneOntologyBiologicalProcesspositive regulation of DNA-templated transcription initiation

PAXIP1 MED15 HNF1B

3.55e-0477373GO:2000144
GeneOntologyBiologicalProcessN-terminal protein amino acid acetylation

CREBBP EP300

3.70e-0416372GO:0006474
GeneOntologyBiologicalProcessregulation of cellular response to heat

CREBBP EP300

3.70e-0416372GO:1900034
GeneOntologyBiologicalProcessregulation of transcription initiation by RNA polymerase II

PAXIP1 MED15 HNF1B

4.12e-0481373GO:0060260
GeneOntologyBiologicalProcesspositive regulation of cell fate commitment

EP300 BRD4

4.70e-0418372GO:0010455
GeneOntologyBiologicalProcessregulation of DNA-templated transcription initiation

PAXIP1 MED15 HNF1B

5.79e-0491373GO:2000142
GeneOntologyBiologicalProcessmodulation by host of symbiont process

CCNK EP300 BRD4

5.79e-0491373GO:0051851
GeneOntologyBiologicalProcessin utero embryonic development

HNF1B CHD7 STIL CNOT1 CCNK BRD4

6.15e-04596376GO:0001701
GeneOntologyBiologicalProcessregulation of transcription elongation by RNA polymerase II

MED15 CCNK BRD4

6.17e-0493373GO:0034243
GeneOntologyBiologicalProcessT-helper 17 cell lineage commitment

EP300 BRD4

7.07e-0422372GO:0072540
GeneOntologyBiologicalProcessregulation of lymphocyte activation

PAXIP1 TOX MEF2C EP300 BRD4 HPS1

7.19e-04614376GO:0051249
GeneOntologyBiologicalProcessDNA-templated transcription initiation

PAXIP1 MED15 HNF1B EP300

7.57e-04231374GO:0006352
GeneOntologyBiologicalProcessorganelle assembly

SMURF1 RPGR STIL ATXN2 CNOT1 MEF2C EP300 HPS1

7.71e-041138378GO:0070925
GeneOntologyBiologicalProcessstimulatory C-type lectin receptor signaling pathway

CREBBP EP300

7.74e-0423372GO:0002223
GeneOntologyBiologicalProcessP-body assembly

ATXN2 CNOT1

7.74e-0423372GO:0033962
GeneOntologyBiologicalProcesscellular response to lectin

CREBBP EP300

7.74e-0423372GO:1990858
GeneOntologyBiologicalProcessresponse to lectin

CREBBP EP300

7.74e-0423372GO:1990840
GeneOntologyBiologicalProcesspositive regulation of T-helper 17 type immune response

EP300 BRD4

7.74e-0423372GO:2000318
GeneOntologyBiologicalProcessregulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains

PAXIP1 MEF2C EP300 BRD4

8.07e-04235374GO:0002822
GeneOntologyBiologicalProcessstem cell population maintenance

MED15 HNF1B CNOT1 CREBBP

8.33e-04237374GO:0019827
GeneOntologyBiologicalProcesspositive regulation of developmental growth

SMURF1 CHD7 MEF2C EP300

8.47e-04238374GO:0048639
GeneOntologyBiologicalProcessregulation of DNA-templated transcription elongation

MED15 CCNK BRD4

8.78e-04105373GO:0032784
GeneOntologyBiologicalProcesscognition

CHD7 MAN2B1 CREBBP MEF2C EP300

8.99e-04423375GO:0050890
GeneOntologyBiologicalProcessmaintenance of cell number

MED15 HNF1B CNOT1 CREBBP

9.01e-04242374GO:0098727
GeneOntologyBiologicalProcesschromatin organization

PAXIP1 CHD7 TOX CREBBP EP300 EMSY BRD4

9.37e-04896377GO:0006325
GeneOntologyBiologicalProcessplatelet formation

MEF2C EP300

9.90e-0426372GO:0030220
GeneOntologyBiologicalProcessmulticellular organism growth

CHD7 STIL ATXN2 EP300

1.00e-03249374GO:0035264
GeneOntologyBiologicalProcessleukocyte activation

PAXIP1 IL16 CHD7 TOX MEF2C EP300 BRD4 HPS1

1.01e-031186378GO:0045321
GeneOntologyBiologicalProcessregulation of adaptive immune response

PAXIP1 MEF2C EP300 BRD4

1.05e-03252374GO:0002819
GeneOntologyBiologicalProcessT-helper cell lineage commitment

EP300 BRD4

1.07e-0327372GO:0002295
GeneOntologyBiologicalProcesshead development

HNF1B CHD7 STIL TOX ATXN2 CREBBP EP300

1.09e-03919377GO:0060322
GeneOntologyBiologicalProcesspeptidyl-lysine acetylation

CREBBP EP300

1.15e-0328372GO:0018394
GeneOntologyBiologicalProcessplatelet morphogenesis

MEF2C EP300

1.15e-0328372GO:0036344
GeneOntologyBiologicalProcesspositive regulation of mitotic cell cycle phase transition

STIL CREBBP BRD4

1.20e-03117373GO:1901992
GeneOntologyBiologicalProcessmelanocyte differentiation

MEF2C HPS1

1.23e-0329372GO:0030318
GeneOntologyBiologicalProcessN-terminal protein amino acid modification

CREBBP EP300

1.23e-0329372GO:0031365
GeneOntologyBiologicalProcessCD4-positive, alpha-beta T cell differentiation

TOX EP300 BRD4

1.26e-03119373GO:0043367
GeneOntologyBiologicalProcessgrowth

SMURF1 HNF1B CHD7 STIL ATXN2 MEF2C EP300 BRD4

1.31e-031235378GO:0040007
GeneOntologyBiologicalProcesspositive regulation of immune system process

PAXIP1 IL16 TOX CREBBP MEF2C EP300 BRD4 HPS1

1.36e-031242378GO:0002684
GeneOntologyBiologicalProcessDNA damage response

PAXIP1 CREBBP CCNK EP300 ZGRF1 EMSY BRD4

1.39e-03959377GO:0006974
GeneOntologyBiologicalProcesspositive regulation of T-helper cell differentiation

EP300 BRD4

1.41e-0331372GO:0045624
GeneOntologyBiologicalProcesstransforming growth factor beta receptor signaling pathway

SMURF1 CREBBP EP300 SMAD5

1.46e-03276374GO:0007179
GeneOntologyBiologicalProcessmembraneless organelle assembly

STIL ATXN2 CNOT1 MEF2C EP300

1.51e-03475375GO:0140694
GeneOntologyBiologicalProcesstranscription elongation by RNA polymerase II

MED15 CCNK BRD4

1.52e-03127373GO:0006368
GeneOntologyBiologicalProcesslymphocyte activation

PAXIP1 CHD7 TOX MEF2C EP300 BRD4 HPS1

1.54e-03976377GO:0046649
GeneOntologyBiologicalProcessanimal organ morphogenesis

AMELY HNF1B CHD7 RPGR STIL MEF2C EP300 HPS1

1.56e-031269378GO:0009887
GeneOntologyBiologicalProcessregulation of T-helper 17 cell differentiation

EP300 BRD4

1.60e-0333372GO:2000319
GeneOntologyBiologicalProcesscellular response to light stimulus

RPGR CREBBP EP300

1.63e-03130373GO:0071482
GeneOntologyBiologicalProcesspositive regulation of cellular response to transforming growth factor beta stimulus

CREBBP EP300

1.79e-0335372GO:1903846
GeneOntologyBiologicalProcesspositive regulation of transforming growth factor beta receptor signaling pathway

CREBBP EP300

1.79e-0335372GO:0030511
GeneOntologyBiologicalProcesspositive regulation of natural killer cell activation

TOX HPS1

1.79e-0335372GO:0032816
GeneOntologyBiologicalProcessbiological process involved in interaction with symbiont

CCNK EP300 BRD4

1.81e-03135373GO:0051702
GeneOntologyBiologicalProcessnuclear receptor-mediated steroid hormone signaling pathway

TRERF1 CNOT1 EP300

1.85e-03136373GO:0030518
GeneOntologyBiologicalProcessresponse to radiation

PAXIP1 RPGR CPT1B CREBBP EP300

1.94e-03503375GO:0009314
GeneOntologyCellularComponentcyclin/CDK positive transcription elongation factor complex

CCNK BRD4

1.09e-049372GO:0008024
GeneOntologyCellularComponentnuclear cyclin-dependent protein kinase holoenzyme complex

CCNK BRD4

4.58e-0418372GO:0019908
GeneOntologyCellularComponenttranscription regulator complex

TRERF1 MED15 HNF1B CREBBP EP300 SMAD5

5.73e-04596376GO:0005667
GeneOntologyCellularComponentcarboxy-terminal domain protein kinase complex

CCNK BRD4

8.21e-0424372GO:0032806
HumanPhenoPapillary cystadenoma of the epididymis

HNF1B CREBBP EP300

3.08e-075173HP:0009715
HumanPhenoEpididymal neoplasm

HNF1B CREBBP EP300

3.08e-075173HP:0030421
HumanPhenoSporadic

HNF1B CHD7 ATXN2 CREBBP MEF2C EP300

6.10e-07103176HP:0003745
HumanPhenoPlantar crease between first and second toes

CREBBP EP300

1.05e-052172HP:0008107
HumanPhenoAortic isthmus hypoplasia

CREBBP EP300

1.05e-052172HP:0034227
HumanPhenoHigh axial triradius

CREBBP EP300

1.05e-052172HP:0001042
HumanPhenoSquare face

CHD7 CREBBP EP300

1.68e-0516173HP:0000321
HumanPhenoAbnormality of the incisor

STIL CNOT1 CREBBP EP300 BRD4

1.97e-05108175HP:0000676
HumanPhenoLaryngeal cartilage malformation

CREBBP EP300

3.14e-053172HP:0008752
HumanPhenoPhobia

CREBBP EP300

3.14e-053172HP:5200232
HumanPhenoAgoraphobia

CREBBP EP300

3.14e-053172HP:0000756
HumanPhenoHumoral immunodeficiency

CREBBP EP300

3.14e-053172HP:0005363
HumanPhenoProminent nasal septum

CREBBP EP300

3.14e-053172HP:0005322
HumanPhenoRadial deviation of thumb terminal phalanx

CREBBP EP300

3.14e-053172HP:0005895
HumanPhenoTrichiasis

CREBBP EP300

6.27e-054172HP:0001128
HumanPhenoVisceral hemangioma

CREBBP EP300

6.27e-054172HP:0410266
HumanPhenoTalon cusp

CREBBP EP300

6.27e-054172HP:0011087
HumanPhenoWidened distal phalanges

CREBBP EP300

6.27e-054172HP:0006200
HumanPhenoVascular ring

CREBBP EP300

6.27e-054172HP:0010775
HumanPhenoHepatic hemangioma

CREBBP EP300

6.27e-054172HP:0031207
HumanPhenoShawl scrotum

HNF1B CREBBP EP300

6.79e-0525173HP:0000049
HumanPhenoAbnormal ureter physiology

HNF1B CHD7 STIL CREBBP EP300 BRD4

9.21e-05245176HP:0025634
HumanPhenoSupernumerary cusp

CREBBP EP300

1.04e-045172HP:0033777
HumanPhenoConductive hearing impairment

CHD7 RPGR MAN2B1 CNOT1 CREBBP EP300 BRD4

1.09e-04373177HP:0000405
HumanPhenoThick eyebrow

MAN2B1 CREBBP MEF2C EP300 BRD4

1.09e-04154175HP:0000574
HumanPhenoAbnormal epididymis morphology

HNF1B CREBBP EP300

1.19e-0430173HP:0009714
HumanPhenoFunctional abnormality of the middle ear

CHD7 RPGR MAN2B1 CNOT1 CREBBP EP300 BRD4

1.36e-04386177HP:0011452
HumanPhenoElbow dislocation

CHD7 CREBBP EP300 BRD4

1.39e-0484174HP:0003042
HumanPhenoAutism

HNF1B CHD7 USF3 CREBBP EP300 BRD4

1.40e-04264176HP:0000717
HumanPhenoPancreatic aplasia

HNF1B CNOT1

1.56e-046172HP:0100801
HumanPhenoLarge foramen magnum

CREBBP EP300

1.56e-046172HP:0002700
HumanPhenoFrontal upsweep of hair

CREBBP EP300 BRD4

1.58e-0433173HP:0002236
HumanPhenoAbnormal branching pattern of the aortic arch

CHD7 CREBBP EP300

1.58e-0433173HP:0011587
HumanPhenoAbnormality of the distal phalanx of the thumb

CNOT1 CREBBP EP300

2.06e-0436173HP:0009617
HumanPhenoDeviated nasal septum

CREBBP EP300

2.18e-047172HP:0004411
HumanPhenoUpper extremity joint dislocation

CHD7 CREBBP EP300 BRD4

2.34e-0496174HP:0030310
HumanPhenoAbnormality of the hairline

HNF1B MAN2B1 CREBBP CCNK EP300 BRD4

2.53e-04294176HP:0009553
HumanPhenoCellular immunodeficiency

USF3 CREBBP EP300

2.62e-0439173HP:0005374
HumanPhenoFunctional abnormality of the bladder

KY CHD7 STIL MAN2B1 ATXN2 CREBBP EP300 BRD4

2.89e-04590178HP:0000009
HumanPhenoLanguage impairment

HNF1B RPGR STIL MAN2B1 ATXN2 CNOT1 CREBBP CCNK MEF2C EP300 BRD4

2.95e-0411781711HP:0002463
HumanPhenoAbnormal hair whorl

CREBBP EP300 BRD4

3.27e-0442173HP:0010721
HumanPhenoRadial deviation of finger

CHD7 CNOT1 CREBBP CCNK MEF2C EP300 BRD4

3.46e-04448177HP:0009466
HumanPhenoPilomatrixoma

CREBBP EP300

3.72e-049172HP:0030434
HumanPhenoCervical cord compression

CREBBP EP300

3.72e-049172HP:0002341
HumanPhenoMeningioma

USF3 CREBBP EP300

3.76e-0444173HP:0002858
HumanPhenoRadial deviation of the hand or of fingers of the hand

CHD7 CNOT1 CREBBP CCNK MEF2C EP300 BRD4

3.86e-04456177HP:0009485
HumanPhenoAbnormality of the bladder

KY CHD7 STIL MAN2B1 ATXN2 CREBBP EP300 BRD4

4.13e-04621178HP:0000014
HumanPhenoHighly arched eyebrow

CHD7 MAN2B1 CREBBP EP300 BRD4

4.28e-04206175HP:0002553
HumanPhenoCongenital abnormal hair pattern

HNF1B MAN2B1 CREBBP CCNK EP300 BRD4

4.51e-04327176HP:0011361
HumanPhenoFrontal hirsutism

CREBBP EP300

4.64e-0410172HP:0011335
HumanPhenoLow posterior hairline

HNF1B CREBBP EP300 BRD4

4.99e-04117174HP:0002162
HumanPhenoAbnormality of the posterior hairline

HNF1B CREBBP EP300 BRD4

4.99e-04117174HP:0030141
HumanPhenoAbnormality of the frontal hairline

MAN2B1 CREBBP CCNK EP300 BRD4

5.22e-04215175HP:0000599
HumanPhenoMaladaptive fear-related cognitions

CHD7 STIL MAN2B1 ATXN2 CREBBP EP300 BRD4

5.51e-04483177HP:5200230
HumanPhenoAnxiety

CHD7 STIL MAN2B1 ATXN2 CREBBP EP300 BRD4

5.51e-04483177HP:0000739
HumanPhenoSpinocerebellar tract degeneration

MAN2B1 ATXN2

5.67e-0411172HP:0002503
HumanPhenoAbnormal subclavian artery morphology

CREBBP EP300

5.67e-0411172HP:0031251
HumanPhenoSelf-mutilation

CHD7 CREBBP EP300

5.82e-0451173HP:0000742
HumanPhenoVesicoureteral reflux

CHD7 STIL CREBBP EP300 BRD4

5.92e-04221175HP:0000076
HumanPhenoAbnormal cerebral ventricle morphology

CHD7 USF3 RPGR STIL MAN2B1 ATXN2 CREBBP MEF2C EP300 BRD4

6.02e-0410461710HP:0002118
HumanPhenoImmunodeficiency

CHD7 USF3 MAN2B1 CREBBP EP300

6.05e-04222175HP:0002721
HumanPhenoAbnormal proximal phalanx morphology of the hand

CREBBP EP300 BRD4

6.17e-0452173HP:0009834
HumanPhenoAbnormal atrioventricular valve morphology

CHD7 MAN2B1 SGO1 CREBBP EP300 BRD4

6.51e-04350176HP:0006705
HumanPhenoAplasia/Hypoplasia of the earlobes

CHD7 CREBBP EP300

6.53e-0453173HP:0009906
HumanPhenoShort thumb

CHD7 CREBBP EP300 BRD4

6.82e-04127174HP:0009778
HumanPhenoDislocated radial head

CHD7 CREBBP EP300

6.89e-0454173HP:0003083
HumanPhenoCerebral white matter atrophy

MAN2B1 ATXN2 CREBBP

6.89e-0454173HP:0012762
HumanPhenoAutistic behavior

HNF1B CHD7 USF3 CREBBP CCNK MEF2C EP300 BRD4

7.59e-04678178HP:0000729
HumanPhenoFacial grimacing

CREBBP EP300

8.00e-0413172HP:0000273
HumanPhenoKeloids

CREBBP EP300

8.00e-0413172HP:0010562
HumanPhenoAbnormality of the spinocerebellar tracts

MAN2B1 ATXN2

8.00e-0413172HP:0003133
HumanPhenoAbnormality of the radial head

CHD7 CREBBP EP300

8.08e-0457173HP:0003995
HumanPhenoAbnormal judgment

CHD7 STIL MAN2B1 ATXN2 CREBBP EP300 BRD4

8.26e-04516177HP:5200401
HumanPhenoRestricted or repetitive behaviors or interests

CHD7 CREBBP CCNK MEF2C EP300 BRD4

8.51e-04368176HP:0031432
HumanPhenoDuplication of phalanx of hallux

CREBBP EP300

9.32e-0414172HP:0010066
HumanPhenoHypoplastic aortic arch

CREBBP EP300

9.32e-0414172HP:0012304
HumanPhenoParietal foramina

CREBBP EP300

9.32e-0414172HP:0002697
HumanPhenoPulmonic stenosis

CHD7 SGO1 CREBBP EP300

9.33e-04138174HP:0001642
HumanPhenoPerseverative thought

CHD7 CREBBP CCNK MEF2C EP300 BRD4

9.68e-04377176HP:0030223
HumanPhenoAbnormal incisor morphology

CREBBP EP300 BRD4

1.03e-0362173HP:0011063
HumanPhenoAbnormality of the humeroradial joint

CHD7 CREBBP EP300

1.03e-0362173HP:0100744
HumanPhenoDeviation of finger

CHD7 CNOT1 CREBBP CCNK MEF2C EP300 BRD4

1.05e-03537177HP:0004097
HumanPhenoAbnormality of the ureter

HNF1B CHD7 STIL CREBBP EP300 BRD4

1.05e-03383176HP:0000069
HumanPhenoAbnormal fear-induced behavior

CHD7 STIL MAN2B1 ATXN2 CREBBP EP300 BRD4

1.06e-03538177HP:0100852
HumanPhenoAbnormal scrotum morphology

HNF1B CHD7 CREBBP EP300

1.07e-03143174HP:0000045
HumanPhenoDuplication of phalanx of toe

CREBBP EP300

1.07e-0315172HP:0010181
HumanPhenoSocial and occupational deterioration

CREBBP EP300

1.07e-0315172HP:0007086
HumanPhenoHypoplastic ilia

MAN2B1 CREBBP EP300

1.08e-0363173HP:0000946
HumanPhenoDisordered formal thought process

CHD7 CREBBP CCNK MEF2C EP300 BRD4

1.10e-03386176HP:0025769
HumanPhenoAbnormality of the uterus

HNF1B CHD7 USF3 EP300 BRD4

1.16e-03256175HP:0000130
HumanPhenoLow anterior hairline

MAN2B1 CREBBP EP300 BRD4

1.18e-03147174HP:0000294
HumanPhenoAplasia/Hypoplasia of the thumb

CHD7 CREBBP EP300 BRD4

1.27e-03150174HP:0009601
HumanPhenoGenital neoplasm

HNF1B USF3 CREBBP EP300

1.27e-03150174HP:0010787
HumanPhenoAbnormal palmar dermatoglyphics

CHD7 CREBBP MEF2C EP300 BRD4

1.35e-03265175HP:0001018
HumanPhenoAbnormality of the lower urinary tract

KY HNF1B CHD7 STIL MAN2B1 ATXN2 CREBBP EP300 BRD4

1.37e-03937179HP:0010936
HumanPhenoPremature thelarche

CREBBP EP300

1.38e-0317172HP:0010314
HumanPhenoAbnormal thought pattern

CHD7 CREBBP CCNK MEF2C EP300 BRD4

1.39e-03404176HP:5200269
HumanPhenoDeviation of the hand or of fingers of the hand

CHD7 CNOT1 CREBBP CCNK MEF2C EP300 BRD4

1.41e-03564177HP:0009484
HumanPhenoDiagnostic behavioral phenotype

HNF1B CHD7 USF3 CREBBP CCNK MEF2C EP300 BRD4

1.46e-03747178HP:0025783
HumanPhenoIntestinal malrotation

RPGR CREBBP EP300 BRD4

1.51e-03157174HP:0002566
MousePhenoabnormal vasculogenesis

PAXIP1 CREBBP EP300 SMAD5

5.06e-0654304MP:0001622
MousePhenoembryonic growth retardation

PAXIP1 HNF1B CHD7 STIL CREBBP MEF2C EP300 BRD4 SMAD5

2.08e-05763309MP:0003984
MousePhenoprenatal growth retardation

PAXIP1 HNF1B CHD7 STIL CREBBP MEF2C EP300 BRD4 SMAD5

5.80e-05869309MP:0010865
MousePhenofailure of heart looping

PAXIP1 MEF2C SMAD5

1.04e-0443303MP:0004251
MousePhenoincomplete somite formation

PAXIP1 MEF2C EP300

1.11e-0444303MP:0001689
MousePhenoabnormal heart development

PAXIP1 CHD7 CREBBP MEF2C EP300 SMAD5

1.18e-04372306MP:0000267
MousePhenoabsent organized vascular network

PAXIP1 CREBBP

1.24e-048302MP:0000263
MousePhenoabnormal vertebrae morphology

KY AMELY SCAF11 CHD7 SGO1 CREBBP EMSY

1.24e-04546307MP:0000137
MousePhenoabnormal vitelline vasculature morphology

PAXIP1 CREBBP MEF2C EP300 SMAD5

1.30e-04235305MP:0003229
MousePhenoabnormal blood vessel morphology

PAXIP1 RNF38 CHD7 RPGR MAN2B1 CREBBP MEF2C EP300 BRD4 HPS1 SMAD5

1.39e-0414723011MP:0001614
MousePhenoabnormal digestive system morphology

AMELY HNF1B CHD7 MAN2B1 TOX ZFHX4 SGO1 CREBBP EP300 SMAD5

1.60e-0412333010MP:0000462
MousePhenoabnormal artery development

PAXIP1 CHD7 MEF2C SMAD5

1.77e-04133304MP:0003410
MousePhenoshort premaxilla

CREBBP BRD4

3.42e-0413302MP:0000091
MousePhenoincomplete embryo turning

PAXIP1 EP300 SMAD5

3.56e-0465303MP:0001701
MousePhenoabnormal placing response

KY CHD7

3.99e-0414302MP:0001526
MousePhenoventricle myocardium hypoplasia

CREBBP MEF2C EP300

4.62e-0471303MP:0010502
MousePhenoembryonic lethality during organogenesis, complete penetrance

PAXIP1 CHD7 STIL CREBBP MEF2C EP300 SMAD5

5.67e-04700307MP:0011098
Domain-

CREBBP EP300

3.82e-0623721.10.246.20
Domainzf-TAZ

CREBBP EP300

3.82e-062372PF02135
DomainZF_TAZ

CREBBP EP300

3.82e-062372PS50134
DomainNuc_rcpt_coact_CREBbp

CREBBP EP300

3.82e-062372IPR014744
DomainHAT_KAT11

CREBBP EP300

3.82e-062372PF08214
DomainKIX

CREBBP EP300

3.82e-062372PS50952
DomainZnF_TAZ

CREBBP EP300

3.82e-062372SM00551
DomainCBP_P300_HAT

CREBBP EP300

3.82e-062372IPR031162
DomainHistone_AcTrfase_Rtt109/CBP

CREBBP EP300

3.82e-062372IPR013178
DomainDUF902

CREBBP EP300

3.82e-062372PF06001
Domain-

CREBBP EP300

3.82e-0623721.20.1020.10
DomainRING_CBP-p300

CREBBP EP300

3.82e-062372IPR010303
DomainKAT11

CREBBP EP300

3.82e-062372SM01250
Domain-

CREBBP EP300

3.82e-0623721.10.1630.10
DomainZnf_TAZ

CREBBP EP300

3.82e-062372IPR000197
DomainKIX_dom

CREBBP EP300

3.82e-062372IPR003101
DomainCreb_binding

CREBBP EP300

3.82e-062372PF09030
DomainKIX

CREBBP EP300

3.82e-062372PF02172
DomainCBP_P300_HAT

CREBBP EP300

3.82e-062372PS51727
DomainBromodomain_CS

CREBBP EP300 BRD4

1.80e-0526373IPR018359
DomainBROMODOMAIN_1

CREBBP EP300 BRD4

5.31e-0537373PS00633
DomainNuc_rcpt_coact

CREBBP EP300

5.70e-056372IPR009110
DomainBromodomain

CREBBP EP300 BRD4

5.76e-0538373PF00439
DomainBROMODOMAIN_2

CREBBP EP300 BRD4

7.24e-0541373PS50014
DomainBROMO

CREBBP EP300 BRD4

7.79e-0542373SM00297
DomainBromodomain

CREBBP EP300 BRD4

7.79e-0542373IPR001487
Domain-

CREBBP EP300 BRD4

7.79e-05423731.20.920.10
DomainHMG_BOX_1

TOX TOX3

1.70e-0410372PS00353
DomainZF_ZZ_2

CREBBP EP300

5.73e-0418372PS50135
DomainZF_ZZ_1

CREBBP EP300

5.73e-0418372PS01357
DomainZZ

CREBBP EP300

5.73e-0418372PF00569
DomainZnf_ZZ

CREBBP EP300

6.39e-0419372IPR000433
DomainZnF_ZZ

CREBBP EP300

6.39e-0419372SM00291
DomainWW

SMURF1 MAGI3

3.90e-0347372PF00397
DomainWW

SMURF1 MAGI3

4.07e-0348372SM00456
DomainSANT

TRERF1 CHD7

4.41e-0350372SM00717
DomainWW_DOMAIN_2

SMURF1 MAGI3

4.58e-0351372PS50020
DomainWW_DOMAIN_1

SMURF1 MAGI3

4.58e-0351372PS01159
DomainWW_dom

SMURF1 MAGI3

4.76e-0352372IPR001202
Domainzf-RING_2

RNF38 SCAF11

4.76e-0352372PF13639
DomainSANT/Myb

TRERF1 CHD7

4.76e-0352372IPR001005
DomainHMG_box

TOX TOX3

4.94e-0353372PF00505
DomainHMG_BOX_2

TOX TOX3

5.12e-0354372PS50118
DomainHMG

TOX TOX3

5.12e-0354372SM00398
Domain-

TOX TOX3

5.31e-03553721.10.30.10
DomainHMG_box_dom

TOX TOX3

7.34e-0365372IPR009071
PathwayWP_ENDODERM_DIFFERENTIATION

TRERF1 HNF1B TOX ZFHX4 EMSY TOX3

4.77e-07143306M39591
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_IN_LATE_STAGE_BRANCHING_MORPHOGENESIS_PANCREATIC_BUD_PRECURSOR_CELLS

HNF1B CREBBP EP300

4.78e-0616303M27121
PathwayWP_MESODERMAL_COMMITMENT_PATHWAY

TRERF1 TOX ZFHX4 EMSY TOX3

1.61e-05153305M39546
PathwayBIOCARTA_CARM_ER_PATHWAY

CREBBP MEF2C EP300

2.19e-0526303M2499
PathwayPID_SMAD2_3NUCLEAR_PATHWAY

MED15 CREBBP MEF2C EP300

2.60e-0582304M2
PathwayKEGG_TGF_BETA_SIGNALING_PATHWAY

SMURF1 CREBBP EP300 SMAD5

3.13e-0586304M2642
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

4.36e-055302MM1575
PathwayREACTOME_NFE2L2_REGULATING_INFLAMMATION_ASSOCIATED_GENES

CREBBP EP300

4.36e-055302M48020
PathwayREACTOME_LRR_FLII_INTERACTING_PROTEIN_1_LRRFIP1_ACTIVATES_TYPE_I_IFN_PRODUCTION

CREBBP EP300

4.36e-055302M27228
PathwayREACTOME_NFE2L2_REGULATING_ER_STRESS_ASSOCIATED_GENES

CREBBP EP300

4.36e-055302M48023
PathwayBIOCARTA_PELP1_PATHWAY

CREBBP EP300

6.53e-056302M22062
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

9.13e-057302MM1573
PathwayREACTOME_REGULATION_OF_BETA_CELL_DEVELOPMENT

HNF1B CREBBP EP300

9.44e-0542303M17541
PathwayBIOCARTA_PPARG_PATHWAY

CREBBP EP300

1.22e-048302M22058
PathwayREACTOME_NFE2L2_REGULATING_MDR_ASSOCIATED_ENZYMES

CREBBP EP300

1.22e-048302M48022
PathwayREACTOME_REGULATION_OF_NFE2L2_GENE_EXPRESSION

CREBBP EP300

1.22e-048302M48024
PathwayREACTOME_NFE2L2_REGULATES_PENTOSE_PHOSPHATE_PATHWAY_GENES

CREBBP EP300

1.22e-048302M46443
PathwayREACTOME_HEME_SIGNALING

CREBBP MEF2C EP300

1.50e-0449303M41832
PathwayKEGG_MEDICUS_REFERENCE_TLR3_IRF3_SIGNALING_PATHWAY

CREBBP EP300

1.56e-049302M47451
PathwayWP_TGFBETA_SIGNALING_PATHWAY

CREBBP EP300 SMAD5

1.90e-0453303MM15880
PathwayREACTOME_REGULATION_OF_FOXO_TRANSCRIPTIONAL_ACTIVITY_BY_ACETYLATION

CREBBP EP300

1.95e-0410302M27945
PathwayWP_TGFBETA_RECEPTOR_SIGNALING

CREBBP EP300 SMAD5

2.12e-0455303M39351
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

2.38e-0411302MM1521
PathwayREACTOME_NFE2L2_REGULATING_TUMORIGENIC_GENES

CREBBP EP300

2.38e-0411302M48021
PathwayREACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR

CREBBP EP300

2.38e-0411302M26924
PathwayWP_TGFBETA_RECEPTOR_SIGNALING_IN_SKELETAL_DYSPLASIAS

CREBBP EP300 SMAD5

2.61e-0459303M39886
PathwayBIOCARTA_CARM1_PATHWAY

CREBBP EP300

2.85e-0412302M7968
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

2.85e-0412302M27765
PathwayPID_RB_1PATHWAY

CREBBP MEF2C EP300

3.48e-0465303M279
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

SMURF1 CCNK EP300 SMAD5

3.56e-04161304M27871
PathwayPID_HDAC_CLASSI_PATHWAY

SMURF1 CREBBP EP300

3.64e-0466303M101
PathwayREACTOME_RUNX3_REGULATES_NOTCH_SIGNALING

CREBBP EP300

3.92e-0414302M27808
PathwayREACTOME_CIRCADIAN_CLOCK

CREBBP MEF2C EP300

4.32e-0470303M938
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

4.52e-0415302MM1339
PathwayBIOCARTA_RELA_PATHWAY

CREBBP EP300

4.52e-0415302M10183
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

4.52e-0415302MM1439
PathwayREACTOME_TRAF3_DEPENDENT_IRF_ACTIVATION_PATHWAY

CREBBP EP300

4.52e-0415302M953
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

5.16e-0416302M1296
PathwayBIOCARTA_IL7_PATHWAY

CREBBP EP300

5.16e-0416302MM1420
PathwayBIOCARTA_PITX2_PATHWAY

CREBBP EP300

5.16e-0416302M8516
PathwayREACTOME_FOXO_MEDIATED_TRANSCRIPTION_OF_CELL_DEATH_GENES

CREBBP EP300

5.16e-0416302M27940
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

5.84e-0417302MM1509
PathwayREACTOME_ZYGOTIC_GENOME_ACTIVATION_ZGA

CREBBP EP300

5.84e-0417302M48025
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

CREBBP EP300

6.56e-0418302M26942
PathwayBIOCARTA_TGFB_PATHWAY

CREBBP EP300

7.32e-0419302M18933
PathwayREACTOME_NFE2L2_REGULATING_ANTI_OXIDANT_DETOXIFICATION_ENZYMES

CREBBP EP300

7.32e-0419302M46442
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_OF_WHITE_ADIPOCYTE_DIFFERENTIATION

MED15 CREBBP EP300

7.38e-0484303M1008
PathwayREACTOME_NOTCH4_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

8.12e-0420302M27881
PathwayWP_HEMATOPOIETIC_STEM_CELL_GENE_REGULATION_BY_GABP_ALPHABETA_COMPLEX

CREBBP EP300

8.97e-0421302M39593
PathwayREACTOME_CD209_DC_SIGN_SIGNALING

CREBBP EP300

8.97e-0421302M27485
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

9.85e-0422302MM1443
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

9.85e-0422302MM1370
PathwayREACTOME_SIGNALING_BY_TGF_BETA_RECEPTOR_COMPLEX

SMURF1 CCNK EP300

1.02e-0394303M1041
PathwayBIOCARTA_NTHI_PATHWAY

CREBBP EP300

1.08e-0323302M2821
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_RUNX3

SMURF1 CREBBP EP300

1.09e-0396303M27784
PathwayREACTOME_RSV_HOST_INTERACTIONS

MED15 CREBBP EP300

1.15e-0398303M48247
PathwayBIOCARTA_VDR_PATHWAY

CREBBP EP300

1.17e-0324302M13404
PathwayWP_WNT_SIGNALING_PATHWAY_AND_PLURIPOTENCY

HNF1B CREBBP EP300

1.26e-03101303MM15829
PathwayREACTOME_NOTCH3_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

1.27e-0325302M27880
PathwayPID_HDAC_CLASSIII_PATHWAY

CREBBP EP300

1.38e-0326302M32
PathwayREACTOME_ATTENUATION_PHASE

CREBBP EP300

1.60e-0328302M27254
PathwayREACTOME_ADIPOGENESIS

MED15 CREBBP EP300

1.61e-03110303M48259
PathwayPID_RETINOIC_ACID_PATHWAY

CREBBP EP300

1.84e-0330302M207
PathwayREACTOME_TRAF6_MEDIATED_IRF7_ACTIVATION

CREBBP EP300

1.84e-0330302M936
PathwayREACTOME_SIGNALING_BY_BMP

SMURF1 SMAD5

1.96e-0331302M1662
PathwayREACTOME_SIGNALING_BY_BMP

SMURF1 SMAD5

1.96e-0331302MM14789
PathwayREACTOME_REGULATION_OF_LIPID_METABOLISM_BY_PPARALPHA

MED15 CREBBP EP300

1.97e-03118303M27316
PathwayREACTOME_SIGNALING_BY_TGFB_FAMILY_MEMBERS

SMURF1 CCNK SMAD5

1.97e-03118303MM15588
PathwayREACTOME_RESPIRATORY_SYNCYTIAL_VIRUS_INFECTION_PATHWAY

MED15 CREBBP EP300

2.07e-03120303M48233
PathwayWP_PRION_DISEASE_PATHWAY

MEF2C EP300

2.09e-0332302M39636
PathwayWP_INITIATION_OF_TRANSCRIPTION_AND_TRANSLATION_ELONGATION_AT_THE_HIV1_LTR

CREBBP EP300

2.09e-0332302M39521
PathwayREACTOME_ACTIVATION_OF_ANTERIOR_HOX_GENES_IN_HINDBRAIN_DEVELOPMENT_DURING_EARLY_EMBRYOGENESIS

PAXIP1 CREBBP EP300

2.16e-03122303M29689
PathwayWP_TYPE_2_PAPILLARY_RENAL_CELL_CARCINOMA

CREBBP EP300

2.35e-0334302M39771
PathwayPID_HIF2PATHWAY

CREBBP EP300

2.35e-0334302M44
PathwayREACTOME_MATERNAL_TO_ZYGOTIC_TRANSITION_MZT

CNOT1 CREBBP EP300

2.48e-03128303M48019
PathwayREACTOME_EVASION_BY_RSV_OF_HOST_INTERFERON_RESPONSES

CREBBP EP300

2.49e-0335302M48246
PathwayREACTOME_SMAD2_SMAD3_SMAD4_HETEROTRIMER_REGULATES_TRANSCRIPTION

CCNK EP300

2.64e-0336302M633
PathwayBIOCARTA_ALK_PATHWAY

MEF2C SMAD5

2.78e-0337302M17400
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

CREBBP EP300

2.93e-0338302M27757
PathwayREACTOME_HSF1_DEPENDENT_TRANSACTIVATION

CREBBP EP300

2.93e-0338302M27255
PathwayPID_P53_DOWNSTREAM_PATHWAY

CREBBP CCNK EP300

3.01e-03137303M145
PathwayPID_FOXM1_PATHWAY

CREBBP EP300

3.25e-0340302M176
PathwayPID_IFNG_PATHWAY

CREBBP EP300

3.25e-0340302M161
PathwayWP_ECTODERM_DIFFERENTIATION

SMURF1 ZFHX4 TOX3

3.33e-03142303M39575
PathwayWP_MALE_INFERTILITY

CREBBP CCNK EP300

3.53e-03145303M39856
PathwayPID_BMP_PATHWAY

SMURF1 SMAD5

3.58e-0342302M181
PathwayWP_MECHANISMS_ASSOCIATED_WITH_PLURIPOTENCY

SMURF1 CREBBP MEF2C EP300

3.60e-03301304MM15983
PathwayPID_HNF3A_PATHWAY

CREBBP EP300

3.92e-0344302M285
PathwayREACTOME_SUMOYLATION_OF_TRANSCRIPTION_COFACTORS

CREBBP EP300

3.92e-0344302M27295
PathwayPID_HNF3B_PATHWAY

HNF1B CPT1B

4.09e-0345302M106
PathwayKEGG_NOTCH_SIGNALING_PATHWAY

CREBBP EP300

4.46e-0347302M7946
PathwayWP_SUDDEN_INFANT_DEATH_SYNDROME_SIDS_SUSCEPTIBILITY_PATHWAYS

CREBBP MEF2C EP300

4.57e-03159303M39373
PathwayWP_ENERGY_METABOLISM

MEF2C EP300

4.65e-0348302M39590
PathwayPID_HES_HEY_PATHWAY

CREBBP EP300

4.65e-0348302M288
PathwayREACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION

CREBBP EP300

4.65e-0348302M611
PathwayBIOCARTA_NFAT_PATHWAY

CREBBP MEF2C

4.84e-0349302MM1442
PathwayREACTOME_TP53_REGULATES_TRANSCRIPTION_OF_CELL_CYCLE_GENES

CNOT1 EP300

4.84e-0349302M27614
PathwayPID_FOXO_PATHWAY

CREBBP EP300

4.84e-0349302M136
PathwayREACTOME_SIGNALING_BY_NOTCH3

CREBBP EP300

4.84e-0349302M618
PathwayREACTOME_TRANSCRIPTIONAL_ACTIVITY_OF_SMAD2_SMAD3_SMAD4_HETEROTRIMER

CCNK EP300

5.23e-0351302M665
Pubmed

cDNAs with long CAG trinucleotide repeats from human brain.

PAXIP1 MED15 ZNF384 ATXN2 TOX3

3.93e-11233859225980
Pubmed

Human transcription factor protein interaction networks.

PAXIP1 TRERF1 MED15 HNF1B SCAF11 CHD7 ZFHX4 ATXN2 CNOT1 CREBBP MEF2C EP300 EMSY SMAD5

1.41e-101429381435140242
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

PAXIP1 TRERF1 MED15 CHD7 CREBBP CCNK EMSY BRD4

4.48e-1026838833640491
Pubmed

Whole-transcriptome sequencing identifies a distinct subtype of acute lymphoblastic leukemia with predominant genomic abnormalities of EP300 and CREBBP.

ZNF384 CREBBP EP300

1.20e-09338327903646
Pubmed

A novel zinc finger protein TReP-132 interacts with CBP/p300 to regulate human CYP11A1 gene expression.

TRERF1 CREBBP EP300

1.20e-09338311349124
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

PAXIP1 TRERF1 MED15 ZNF384 CHD7 ATXN2 CNOT1 CREBBP CCNK EP300 EMSY BRD4

1.23e-091103381234189442
Pubmed

Interaction network of human early embryonic transcription factors.

PAXIP1 TRERF1 MED15 CHD7 ZFHX4 CREBBP EP300 EMSY

3.73e-0935138838297188
Pubmed

Molecular mechanisms of myogenic coactivation by p300: direct interaction with the activation domain of MyoD and with the MADS box of MEF2C.

CREBBP MEF2C EP300

4.81e-0943839001254
Pubmed

GA-binding protein factors, in concert with the coactivator CREB binding protein/p300, control the induction of the interleukin 16 promoter in T lymphocytes.

IL16 CREBBP EP300

1.20e-0853839990060
Pubmed

Hgs physically interacts with Smad5 and attenuates BMP signaling.

SMURF1 EP300 SMAD5

1.20e-08538316516194
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

PAXIP1 MED15 CHD7 ZFHX4 CREBBP EP300 BRD4

2.27e-0739838735016035
Pubmed

Identification of the hypoxia-inducible factor 2α nuclear interactome in melanoma cells reveals master proteins involved in melanoma development.

MED15 CNOT1 CREBBP EP300

8.32e-076638423275444
Pubmed

Acetylation-regulated interaction between p53 and SET reveals a widespread regulatory mode.

CREBBP EP300 BRD4

1.15e-061938327626385
Pubmed

Loss of p300 accelerates MDS-associated leukemogenesis.

CREBBP EP300

1.16e-06238227881875
Pubmed

Molecular characterization of the histone acetyltransferase CREBBP/EP300 genes in myeloid neoplasia.

CREBBP EP300

1.16e-06238234845315
Pubmed

p300 plays a critical role in maintaining cardiac mitochondrial function and cell survival in postnatal hearts.

CREBBP EP300

1.16e-06238219729597
Pubmed

Endogenous CCAAT/enhancer binding protein beta and p300 are both regulated by growth hormone to mediate transcriptional activation.

CREBBP EP300

1.16e-06238215860545
Pubmed

Further delineation of an entity caused by CREBBP and EP300 mutations but not resembling Rubinstein-Taybi syndrome.

CREBBP EP300

1.16e-06238229460469
Pubmed

Expression of p300 and CBP is associated with poor prognosis in small cell lung cancer.

CREBBP EP300

1.16e-06238224551300
Pubmed

Pre-B acute lymphoblastic leukaemia recurrent fusion, EP300-ZNF384, is associated with a distinct gene expression.

ZNF384 EP300

1.16e-06238229531323
Pubmed

Genome-wide CRISPR screens reveal synthetic lethal interaction between CREBBP and EP300 in diffuse large B-cell lymphoma.

CREBBP EP300

1.16e-06238233911074
Pubmed

The adenovirus 12 E1A proteins can bind directly to proteins of the p300 transcription co-activator family, including the CREB-binding protein CBP and p300.

CREBBP EP300

1.16e-0623829018065
Pubmed

Coactivators p300 and CBP maintain the identity of mouse embryonic stem cells by mediating long-range chromatin structure.

CREBBP EP300

1.16e-06238224648406
Pubmed

CBP and P300 regulate distinct gene networks required for human primary myoblast differentiation and muscle integrity.

CREBBP EP300

1.16e-06238230135524
Pubmed

CREB-binding protein/P300 bromodomain inhibition reduces neutrophil accumulation and activates antitumor immunity in triple-negative breast cancer.

CREBBP EP300

1.16e-06238239287984
Pubmed

Distribution of co-activators CBP and p300 during mouse oocyte and embryo development.

CREBBP EP300

1.16e-06238216596650
Pubmed

The p300 and CBP Transcriptional Coactivators Are Required for β-Cell and α-Cell Proliferation.

CREBBP EP300

1.16e-06238229217654
Pubmed

Exon deletions of the EP300 and CREBBP genes in two children with Rubinstein-Taybi syndrome detected by aCGH.

CREBBP EP300

1.16e-06238220717166
Pubmed

Differences in the interactions of oncogenic adenovirus 12 early region 1A and nononcogenic adenovirus 2 early region 1A with the cellular coactivators p300 and CBP.

CREBBP EP300

1.16e-06238210049825
Pubmed

CBP/p300 acetyltransferase activity in hematologic malignancies.

CREBBP EP300

1.16e-06238227380996
Pubmed

CREBBP and p300 lysine acetyl transferases in the DNA damage response.

CREBBP EP300

1.16e-06238229170789
Pubmed

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

CREBBP EP300

1.16e-06238225893291
Pubmed

Human T-lymphotropic virus type 1 p30(II) regulates gene transcription by binding CREB binding protein/p300.

CREBBP EP300

1.16e-06238211559821
Pubmed

Crebbp haploinsufficiency in mice alters the bone marrow microenvironment, leading to loss of stem cells and excessive myelopoiesis.

CREBBP EP300

1.16e-06238221555743
Pubmed

CBP/p300 induction is required for retinoic acid sensitivity in human mammary cells.

CREBBP EP300

1.16e-06238212646247
Pubmed

CARM1 inhibition reduces histone acetyltransferase activity causing synthetic lethality in CREBBP/EP300-mutated lymphomas.

CREBBP EP300

1.16e-06238232576962
Pubmed

Syndromic features and mild cognitive impairment in mice with genetic reduction on p300 activity: Differential contribution of p300 and CBP to Rubinstein-Taybi syndrome etiology.

CREBBP EP300

1.16e-06238219822209
Pubmed

A specific CBP/p300-dependent gene expression programme drives the metabolic remodelling in late stages of spermatogenesis.

CREBBP EP300

1.16e-06238224522976
Pubmed

Histone acetyltransferase activities of cAMP-regulated enhancer-binding protein and p300 in tissues of fetal, young, and old mice.

CREBBP EP300

1.16e-06238211867645
Pubmed

CBP is required for environmental enrichment-induced neurogenesis and cognitive enhancement.

CREBBP EP300

1.16e-06238221847097
Pubmed

Expression of the nuclear coactivators CBP and p300 in developing craniofacial tissue.

CREBBP EP300

1.16e-06238211963968
Pubmed

p300 or CBP is required for insulin-stimulated glucose uptake in skeletal muscle and adipocytes.

CREBBP EP300

1.16e-06238234813504
Pubmed

Differential transcriptional activation by human T-cell leukemia virus type 1 Tax mutants is mediated by distinct interactions with CREB binding protein and p300.

CREBBP EP300

1.16e-0623829528808
Pubmed

Analysis of genetic stability at the EP300 and CREBBP loci in a panel of cancer cell lines.

CREBBP EP300

1.16e-06238212696060
Pubmed

Rubinstein-Taybi Syndrome

CREBBP EP300

1.16e-06238220301699
Pubmed

CBP Is Required for Establishing Adaptive Gene Programs in the Adult Mouse Brain.

CREBBP EP300

1.16e-06238236109165
Pubmed

Potential biomarker of metformin action.

CREBBP EP300

1.16e-06238224639469
Pubmed

The histone acetyl transferases CBP and p300 regulate stress response pathways in synovial fibroblasts at transcriptional and functional levels.

CREBBP EP300

1.16e-06238237816914
Pubmed

TOX defines a conserved subfamily of HMG-box proteins.

TOX TOX3

1.16e-06238212697058
Pubmed

Retinoids and retinoic acid receptors regulate growth arrest and apoptosis in human mammary epithelial cells and modulate expression of CBP/p300.

CREBBP EP300

1.16e-06238212242694
Pubmed

Binding of p300/CBP co-activators by polyoma large T antigen.

CREBBP EP300

1.16e-06238211438528
Pubmed

Smad-dependent stimulation of type I collagen gene expression in human skin fibroblasts by TGF-beta involves functional cooperation with p300/CBP transcriptional coactivators.

CREBBP EP300

1.16e-06238210918613
Pubmed

CBP/p300 Drives the Differentiation of Regulatory T Cells through Transcriptional and Non-Transcriptional Mechanisms.

CREBBP EP300

1.16e-06238231182547
Pubmed

Histone Acetyltransferases p300 and CBP Coordinate Distinct Chromatin Remodeling Programs in Vascular Smooth Muscle Plasticity.

CREBBP EP300

1.16e-06238235502657
Pubmed

Rubinstein-Taybi syndrome in a Saudi boy with distinct features and variants in both the CREBBP and EP300 genes: a case report.

CREBBP EP300

1.16e-06238230635043
Pubmed

p300 and cAMP response element-binding protein-binding protein in skeletal muscle homeostasis, contractile function, and survival.

CREBBP EP300

1.16e-06238231898871
Pubmed

Phenotype and genotype in 52 patients with Rubinstein-Taybi syndrome caused by EP300 mutations.

CREBBP EP300

1.16e-06238227648933
Pubmed

Germline or inducible knockout of p300 or CBP in skeletal muscle does not alter insulin sensitivity.

CREBBP EP300

1.16e-06238230888860
Pubmed

Exploitation of EP300 and CREBBP Lysine Acetyltransferases by Cancer.

CREBBP EP300

1.16e-06238227881443
Pubmed

Spatiotemporal expression of histone acetyltransferases, p300 and CBP, in developing embryonic hearts.

CREBBP EP300

1.16e-06238219272189
Pubmed

Developmentally regulated expression of the transcriptional cofactors/histone acetyltransferases CBP and p300 during mouse embryogenesis.

CREBBP EP300

1.16e-06238210610021
Pubmed

Emerging roles of p300/CBP in autophagy and autophagy-related human disorders.

CREBBP EP300

1.16e-06238237314181
Pubmed

Distinct roles for CREB-binding protein and p300 in hematopoietic stem cell self-renewal.

CREBBP EP300

1.16e-06238212397173
Pubmed

CBP/p300 TAZ1 domain forms a structured scaffold for ligand binding.

CREBBP EP300

1.16e-06238215641773
Pubmed

Differential contribution of p300 and CBP to regulatory element acetylation in mESCs.

CREBBP EP300

1.16e-06238232690000
Pubmed

Interaction of human immunodeficiency virus type 1 Tat with the transcriptional coactivators p300 and CREB binding protein.

CREBBP EP300

1.16e-0623829733868
Pubmed

CBP/p300 antagonises EGFR-Ras-Erk signalling and suppresses increased Ras-Erk signalling-induced tumour formation in mice.

CREBBP EP300

1.16e-06238230953353
Pubmed

Disrupting the CH1 domain structure in the acetyltransferases CBP and p300 results in lean mice with increased metabolic control.

CREBBP EP300

1.16e-06238221803292
Pubmed

HIV-1 tat transactivator recruits p300 and CREB-binding protein histone acetyltransferases to the viral promoter.

CREBBP EP300

1.16e-0623829811832
Pubmed

Two independent regions of simian virus 40 T antigen increase CBP/p300 levels, alter patterns of cellular histone acetylation, and immortalize primary cells.

CREBBP EP300

1.16e-06238224089570
Pubmed

Rubinstein-Taybi syndrome in Chinese population with four novel mutations.

CREBBP EP300

1.16e-06238233063428
Pubmed

EP300/CBP is crucial for cAMP-PKA pathway to alleviate podocyte dedifferentiation via targeting Notch3 signaling.

CREBBP EP300

1.16e-06238234506759
Pubmed

Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms.

CREBBP EP300

1.16e-06238222177454
Pubmed

Genetic heterogeneity in Rubinstein-Taybi syndrome: mutations in both the CBP and EP300 genes cause disease.

CREBBP EP300

1.16e-06238215706485
Pubmed

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer.

CREBBP EP300

1.16e-06238239266679
Pubmed

A boy with classical Rubinstein-Taybi syndrome but no detectable mutation in the CREBBP and EP300 genes.

CREBBP EP300

1.16e-06238222303793
Pubmed

Inhibition of histone acetyltransferase function radiosensitizes CREBBP/EP300 mutants via repression of homologous recombination, potentially targeting a gain of function.

CREBBP EP300

1.16e-06238234732714
Pubmed

Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition.

CREBBP EP300

1.16e-06238234019788
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

CREBBP EP300 EMSY BRD4

1.39e-067538425593309
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

MED15 CNOT1 CREBBP CCNK EP300 EMSY BRD4

1.94e-0654938738280479
Pubmed

Composite co-activator ARC mediates chromatin-directed transcriptional activation.

MED15 CREBBP EP300

2.10e-062338310235267
Pubmed

Dendrite development regulated by CREST, a calcium-regulated transcriptional activator.

CREBBP EP300

3.48e-06338214716005
Pubmed

The human T-cell leukemia virus type 1 tax protein confers CBP/p300 recruitment and transcriptional activation properties to phosphorylated CREB.

CREBBP EP300

3.48e-06338218070920
Pubmed

The acetylation of transcription factor HBP1 by p300/CBP enhances p16INK4A expression.

CREBBP EP300

3.48e-06338221967847
Pubmed

EP300-ZNF384 fusion gene product up-regulates GATA3 gene expression and induces hematopoietic stem cell gene expression signature in B-cell precursor acute lymphoblastic leukemia cells.

ZNF384 EP300

3.48e-06338228378055
Pubmed

CBP and p300 are essential for renin cell identity and morphological integrity of the kidney.

CREBBP EP300

3.48e-06338219252086
Pubmed

Inhibition of p300/CBP by early B-cell factor.

CREBBP EP300

3.48e-06338212748286
Pubmed

Brd4-p300 inhibition downregulates Nox4 and accelerates lung fibrosis resolution in aged mice.

EP300 BRD4

3.48e-06338232544088
Pubmed

p300 interacts with the N- and C-terminal part of PPARgamma2 in a ligand-independent and -dependent manner, respectively.

CREBBP EP300

3.48e-06338210075656
Pubmed

Genetic interaction between mutations in c-Myb and the KIX domains of CBP and p300 affects multiple blood cell lineages and influences both gene activation and repression.

CREBBP EP300

3.48e-06338224340053
Pubmed

Acetylation of Nrf2 by p300/CBP augments promoter-specific DNA binding of Nrf2 during the antioxidant response.

CREBBP EP300

3.48e-06338219273602
Pubmed

Activation of Stat3 sequence-specific DNA binding and transcription by p300/CREB-binding protein-mediated acetylation.

CREBBP EP300

3.48e-06338215649887
Pubmed

Expression patterns of histone acetyltransferases p300 and CBP during murine tooth development.

CREBBP EP300

3.48e-06338222179676
Pubmed

CBP/p300 are bimodal regulators of Wnt signaling.

CREBBP EP300

3.48e-06338217410209
Pubmed

DUX4 recruits p300/CBP through its C-terminus and induces global H3K27 acetylation changes.

CREBBP EP300

3.48e-06338226951377
Pubmed

CBP/p300 and SIRT1 are involved in transcriptional regulation of S-phase specific histone genes.

CREBBP EP300

3.48e-06338221789216
Pubmed

Mastermind mediates chromatin-specific transcription and turnover of the Notch enhancer complex.

CREBBP EP300

3.48e-06338212050117
Pubmed

Two transactivation mechanisms cooperate for the bulk of HIF-1-responsive gene expression.

CREBBP EP300

3.48e-06338216237459
Pubmed

A transcription-factor-binding surface of coactivator p300 is required for haematopoiesis.

CREBBP EP300

3.48e-06338212384703
Pubmed

Regulation of transcription factor C/ATF by the cAMP signal activation in hippocampal neurons, and molecular interaction of C/ATF with signal integrator CBP/p300.

CREBBP EP300

3.48e-06338210350644
InteractionSOX7 interactions

PAXIP1 CHD7 ZFHX4 CREBBP EP300 SMAD5

7.92e-0982376int:SOX7
InteractionCRX interactions

PAXIP1 TRERF1 MED15 HNF1B CHD7 ZFHX4 CREBBP EP300

1.61e-08254378int:CRX
InteractionSOX9 interactions

PAXIP1 HNF1B CHD7 CREBBP EP300 BRD4

2.19e-0897376int:SOX9
InteractionEGR2 interactions

PAXIP1 TRERF1 CHD7 ZFHX4 CREBBP EP300 EMSY

2.33e-08171377int:EGR2
InteractionPAX8 interactions

PAXIP1 HNF1B CHD7 ZFHX4 CREBBP EP300

4.93e-08111376int:PAX8
InteractionTBR1 interactions

PAXIP1 HNF1B CHD7 ZFHX4 EP300 BRD4

5.48e-08113376int:TBR1
InteractionPAX7 interactions

PAXIP1 HNF1B CHD7 ZFHX4 CREBBP EP300

9.55e-08124376int:PAX7
InteractionRUNX2 interactions

MED15 SMURF1 CREBBP EP300 BRD4 SMAD5

1.05e-07126376int:RUNX2
InteractionERG interactions

PAXIP1 CHD7 ZFHX4 CREBBP EP300 EMSY BRD4

1.44e-07223377int:ERG
InteractionMED23 interactions

PAXIP1 MED15 CREBBP CCNK EP300 EMSY BRD4

4.73e-07266377int:MED23
InteractionXRCC6 interactions

PAXIP1 SMURF1 HNF1B SCAF11 CHD7 SGO1 CREBBP CCNK EP300 EMSY BRD4

5.28e-079283711int:XRCC6
InteractionTEAD1 interactions

PAXIP1 CHD7 ZFHX4 CREBBP MEF2C EP300

7.56e-07176376int:TEAD1
InteractionRBBP5 interactions

PAXIP1 HNF1B CHD7 CREBBP EP300 EMSY BRD4

7.89e-07287377int:RBBP5
InteractionSP7 interactions

PAXIP1 TRERF1 HNF1B CHD7 ZFHX4 CREBBP EP300

1.16e-06304377int:SP7
InteractionHNF1B interactions

PAXIP1 HNF1B CHD7 ZFHX4 CREBBP EP300

1.18e-06190376int:HNF1B
InteractionCEBPA interactions

PAXIP1 TRERF1 MED15 ZNF384 CHD7 ATXN2 CNOT1 CREBBP CCNK EP300 EMSY BRD4

1.28e-0612453712int:CEBPA
InteractionFEV interactions

PAXIP1 CHD7 ZFHX4 CREBBP EP300 EMSY

1.74e-06203376int:FEV
InteractionRUNX1 interactions

PAXIP1 RNF38 MAGI3 CREBBP CCNK EP300 SMAD5

1.77e-06324377int:RUNX1
InteractionTBXT interactions

PAXIP1 CHD7 ZFHX4 CREBBP EP300

2.18e-06116375int:TBXT
InteractionKLF2 interactions

SMURF1 CREBBP EP300

2.55e-0615373int:KLF2
InteractionYAP1 interactions

TRERF1 MED15 SMURF1 RNF38 HNF1B CNOT1 CREBBP CCNK EP300 BRD4 SMAD5

2.68e-0610953711int:YAP1
InteractionPAX6 interactions

PAXIP1 HNF1B CHD7 ZFHX4 CREBBP EP300 SMAD5

3.96e-06366377int:PAX6
InteractionMYB interactions

PAXIP1 CHD7 CREBBP EP300 EMSY

4.27e-06133375int:MYB
InteractionRUNX3 interactions

SMURF1 EP300 BRD4 SMAD5

4.66e-0661374int:RUNX3
InteractionTLE3 interactions

TRERF1 MED15 HNF1B CREBBP EP300 EMSY BRD4

4.73e-06376377int:TLE3
InteractionSMAD2 interactions

PAXIP1 MED15 SMURF1 CREBBP MEF2C EP300 SMAD5

5.52e-06385377int:SMAD2
InteractionH3-3A interactions

SMURF1 ZNF384 SCAF11 CHD7 SGO1 CREBBP EP300 EMSY BRD4

6.29e-06749379int:H3-3A
InteractionGUSBP5 interactions

STIL ZFHX4 ATXN2 EMSY

1.06e-0575374int:GUSBP5
InteractionHNF1A interactions

PAXIP1 HNF1B CREBBP EP300

1.38e-0580374int:HNF1A
InteractionEPAS1 interactions

MED15 CNOT1 CREBBP MEF2C EP300

1.54e-05173375int:EPAS1
InteractionTLX1 interactions

PAXIP1 CHD7 ZFHX4 CREBBP EP300

1.62e-05175375int:TLX1
InteractionPAX2 interactions

PAXIP1 HNF1B CHD7 ZFHX4

1.75e-0585374int:PAX2
InteractionGSC interactions

PAXIP1 ZFHX4 CREBBP EP300

1.92e-0587374int:GSC
InteractionGATA3 interactions

PAXIP1 CHD7 ZFHX4 CREBBP EP300

2.23e-05187375int:GATA3
InteractionNFIA interactions

PAXIP1 MED15 HNF1B CREBBP EP300

2.29e-05188375int:NFIA
InteractionNANOG interactions

PAXIP1 TRERF1 SCAF11 CHD7 CNOT1 EP300 EMSY

2.34e-05481377int:NANOG
InteractionSOX10 interactions

PAXIP1 HNF1B CHD7 EP300

2.39e-0592374int:SOX10
InteractionFOXI1 interactions

PAXIP1 ZFHX4 CREBBP EP300

2.39e-0592374int:FOXI1
InteractionTRERF1 interactions

TRERF1 CREBBP EP300

2.99e-0533373int:TRERF1
InteractionGATA2 interactions

PAXIP1 CHD7 ZFHX4 CREBBP EP300

3.01e-05199375int:GATA2
InteractionCNOT3 interactions

MED15 STIL CNOT1 CREBBP EP300

3.63e-05207375int:CNOT3
InteractionSND1 interactions

SMURF1 SCAF11 CNOT1 CREBBP EP300 BRD4

3.70e-05347376int:SND1
InteractionING1 interactions

SMURF1 HNF1B CREBBP EP300

3.73e-05103374int:ING1
InteractionNFIC interactions

PAXIP1 SMURF1 SCAF11 CREBBP BRD4

3.89e-05210375int:NFIC
InteractionEN1 interactions

PAXIP1 CHD7 ZFHX4 EP300

4.83e-05110374int:EN1
InteractionNCOA3 interactions

HNF1B CREBBP MEF2C EP300 BRD4

5.29e-05224375int:NCOA3
InteractionPROX1 interactions

CREBBP EP300 BRD4

5.79e-0541373int:PROX1
InteractionAR interactions

PAXIP1 TRERF1 MED15 CHD7 CREBBP CCNK EP300 EMSY BRD4

5.84e-05992379int:AR
InteractionMED28 interactions

MED15 MAGI3 CNOT1 BRD4

5.94e-05116374int:MED28
InteractionGPKOW interactions

PAXIP1 TRERF1 ATXN2 BRD4

6.35e-05118374int:GPKOW
InteractionJUNB interactions

SMURF1 CREBBP EP300 BRD4

6.35e-05118374int:JUNB
InteractionUBTF interactions

SMURF1 CNOT1 CREBBP EP300 BRD4

6.51e-05234375int:UBTF
InteractionETS1 interactions

PAXIP1 CREBBP EP300 EMSY

7.01e-05121374int:ETS1
InteractionASCL1 interactions

MEF2C EP300 BRD4

7.67e-0545373int:ASCL1
InteractionFHL2 interactions

IL16 CNOT1 CREBBP EP300 EMSY TOX3

7.69e-05396376int:FHL2
InteractionSMAD1 interactions

MED15 SMURF1 CREBBP EP300 SMAD5

7.78e-05243375int:SMAD1
InteractionEYA4 interactions

MED15 HNF1B CREBBP CCNK EP300

7.78e-05243375int:EYA4
InteractionCDC16 interactions

PAXIP1 STIL CREBBP EP300 BRD4

8.24e-05246375int:CDC16
InteractionATXN1 interactions

MED15 HNF1B TOX ATXN2 CNOT1 CREBBP CCNK BRD4 TOX3

8.35e-051039379int:ATXN1
InteractionMARF1 interactions

STIL ATXN2 CNOT1 CREBBP

8.72e-05128374int:MARF1
InteractionASF1A interactions

ZNF384 HNF1B CHD7 EP300 EMSY

8.73e-05249375int:ASF1A
InteractionPAX9 interactions

PAXIP1 CHD7 ZFHX4 EP300

9.26e-05130374int:PAX9
InteractionMDC1 interactions

PAXIP1 ATXN2 CREBBP EP300 EMSY BRD4

9.82e-05414376int:MDC1
InteractionWEE1 interactions

PAXIP1 SMURF1 EP300 BRD4

1.01e-04133374int:WEE1
InteractionOXER1 interactions

RNF38 HNF1B CCNK

1.05e-0450373int:OXER1
InteractionWWTR1 interactions

IL16 CNOT1 CREBBP EP300 EMSY BRD4

1.09e-04422376int:WWTR1
InteractionEID1 interactions

SCAF11 CREBBP EP300

1.12e-0451373int:EID1
InteractionNUP35 interactions

MED15 HNF1B ATXN2 CNOT1 CREBBP EP300

1.12e-04424376int:NUP35
InteractionANAPC5 interactions

PAXIP1 SMURF1 CREBBP EP300

1.17e-04138374int:ANAPC5
InteractionASH2L interactions

PAXIP1 SMURF1 CHD7 EP300 EMSY

1.17e-04265375int:ASH2L
InteractionHOXB3 interactions

CREBBP EP300

1.17e-049372int:HOXB3
InteractionARGFX interactions

CREBBP EP300

1.17e-049372int:ARGFX
InteractionGTF2B interactions

SMURF1 CREBBP EP300 BRD4

1.27e-04141374int:GTF2B
InteractionNCOA2 interactions

HNF1B CREBBP MEF2C EP300

1.27e-04141374int:NCOA2
InteractionNFIB interactions

PAXIP1 HNF1B CREBBP BRD4

1.30e-04142374int:NFIB
InteractionHDAC1 interactions

TRERF1 HNF1B ZFHX4 CREBBP EP300 ZGRF1 EMSY BRD4 SMAD5

1.37e-041108379int:HDAC1
InteractionHNF4A interactions

PAXIP1 CHD7 CREBBP EP300 EMSY

1.39e-04275375int:HNF4A
InteractionNCOA6 interactions

PAXIP1 MED15 CREBBP EP300

1.41e-04145374int:NCOA6
InteractionELF5 interactions

PAXIP1 CHD7 EP300 EMSY

1.49e-04147374int:ELF5
InteractionPOU6F2 interactions

ZNF384 HNF1B CCNK SMAD5

1.53e-04148374int:POU6F2
InteractionRTF1 interactions

MED15 CCNK EP300 BRD4

1.61e-04150374int:RTF1
InteractionSREBF1 interactions

MED15 SMURF1 CREBBP EP300

1.61e-04150374int:SREBF1
InteractionYY1 interactions

HNF1B CHD7 CREBBP EP300 EMSY BRD4

1.63e-04454376int:YY1
InteractionSOX2 interactions

PAXIP1 TRERF1 ZNF384 HNF1B CHD7 ZFHX4 CNOT1 CCNK MEF2C EP300

1.77e-0414223710int:SOX2
InteractionTLX3 interactions

PAXIP1 HNF1B CHD7 ZFHX4 EP300

1.81e-04291375int:TLX3
InteractionSOX6 interactions

HNF1B CHD7 ZFHX4 TOX3

1.92e-04157374int:SOX6
InteractionHOXA10 interactions

CREBBP EP300 BRD4

2.00e-0462373int:HOXA10
InteractionEDC3 interactions

STIL ATXN2 EP300 BRD4

2.11e-04161374int:EDC3
InteractionKDM6A interactions

PAXIP1 HNF1B CREBBP BRD4

2.16e-04162374int:KDM6A
InteractionANAPC7 interactions

PAXIP1 CREBBP EP300 BRD4

2.16e-04162374int:ANAPC7
InteractionSOX5 interactions

HNF1B CHD7 ZFHX4 SMAD5

2.16e-04162374int:SOX5
InteractionATF1 interactions

HNF1B CREBBP BRD4

2.30e-0465373int:ATF1
InteractionPPARG interactions

PAXIP1 SMURF1 CNOT1 CREBBP EP300

2.32e-04307375int:PPARG
InteractionH2BC21 interactions

SMURF1 SCAF11 CHD7 USF3 CREBBP EP300 BRD4

2.37e-04696377int:H2BC21
InteractionDCP1A interactions

PAXIP1 STIL ATXN2 CNOT1

2.37e-04166374int:DCP1A
InteractionKDM1A interactions

TRERF1 IL16 CHD7 ZFHX4 CNOT1 EP300 ZGRF1 BRD4

2.53e-04941378int:KDM1A
InteractionTP73 interactions

MED15 RNF38 CREBBP EP300

2.54e-04169374int:TP73
InteractionRXRA interactions

CNOT1 CREBBP EP300 BRD4

2.54e-04169374int:RXRA
InteractionKMT2D interactions

PAXIP1 HNF1B CREBBP EP300

2.54e-04169374int:KMT2D
InteractionSETD1A interactions

PAXIP1 CREBBP CCNK EP300

2.60e-04170374int:SETD1A
CytobandEnsembl 112 genes in cytogenetic band chr8q12

CHD7 TOX

2.66e-0392382chr8q12
GeneFamilyAtaxins|Trinucleotide repeat containing

PAXIP1 MED15 ZNF384 ATXN2 TOX3

1.72e-1025255775
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

2.46e-0417252486
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

CREBBP EP300

2.77e-041825291
GeneFamilyGATA zinc finger domain containing|Myb/SANT domain containing

TRERF1 CHD7

2.42e-0353252532
GeneFamilyPDZ domain containing

MAGI3 IL16

1.86e-021522521220
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500

PAXIP1 SCAF11 CHD7 RPGR STIL TOX SGO1 CCNK ZGRF1 EMSY BRD4 SMAD5 TOX3

2.55e-0714593513facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_LatNas_2500_K3

PAXIP1 SCAF11 RPGR STIL TOX SGO1 CCNK ZGRF1 EMSY BRD4 SMAD5 TOX3

4.11e-0712573512facebase_RNAseq_e10.5_Emin_LatNas_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#3

PAXIP1 MAGI3 SCAF11 CHD7 STIL SGO1 CNOT1 CCNK

1.91e-06532358Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_MaxArch_2500_K3

IL16 CHD7 RPGR STIL TOX SGO1 EMSY BRD4 SMAD5 TOX3

2.32e-0512523510facebase_RNAseq_e10.5_MaxArch_2500_K3
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

CHD7 RPGR STIL CPT1B TOX SGO1 EMSY SMAD5 TOX3

4.05e-051060359facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasdev gonad_e12.5_M_SertoliCell_Sox9_k-means-cluster#4_top-relative-expression-ranked_1000

CHD7 TOX MEF2C

5.19e-0544353gudmap_dev gonad_e12.5_M_SertoliCell_Sox9_k4_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_MandArch_2500_K1

SCAF11 CHD7 RPGR STIL TOX SGO1 EMSY BRD4 SMAD5

1.37e-041241359facebase_RNAseq_e10.5_MandArch_2500_K1
CoexpressionAtlasFacebaseRNAseq_e10.5_Lateral Nasal Eminence_top-relative-expression-ranked_1000

HNF1B SCAF11 CHD7 USF3 RPGR ZFHX4 EMSY SMAD5

1.60e-04985358Facebase_RNAseq_e10.5_Lateral Nasal Eminence_1000
CoexpressionAtlasfacebase_RNAseq_e10.5_NeuroEpith_central_2500_K4

RNF38 CHD7 STIL CPT1B SGO1 EMSY BRD4 HPS1 TOX3

2.88e-041370359facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

CHD7 RPGR STIL CPT1B TOX SGO1 EMSY SMAD5 TOX3

3.64e-041414359facebase_RNAseq_e10.5_Emin_MedNas_2500
ToppCellControl-T/NK_proliferative|World / Disease group and Cell class

MAGI3 RPGR STIL SGO1

1.28e-05169384fca735cbb55fce4d32dc6632a39acea1d16b87ab
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL CPT1B SGO1 ZGRF1

1.79e-0518438416aa8e88bdd51b1d132d5cf33c29963b384a8bae
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CHD7 RPGR FEM1C MEF2C

1.87e-0518638455b239834b96b1f7787ec77a7d19796d617bbbf0
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

FEM1C ATXN2 CNOT1 SMAD5

2.08e-05191384d7920f4a602b50d0ef064eb47001e71939695ed2
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

MAGI3 SCAF11 ATXN2 TOX3

2.12e-05192384916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_aging_sig-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SCAF11 IL16 MAN2B1 MEF2C

2.12e-0519238469758a256386a6ed3a6e2c94c55d59baa34892d7
ToppCellhuman_hepatoblastoma|World / Sample and Cell Type and Tumor Cluster (all cells)

MAGI3 SCAF11 ATXN2 TOX3

2.16e-05193384e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-NPC-like-NPC-like_neural-E|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

CHD7 TOX TOX3 AKNAD1

2.21e-05194384b111d10c99d7ff7eb261cd7786cd9d9a549049b1
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

IL16 RPGR MAN2B1 MEF2C

2.21e-05194384d852aebf7a763b9a776c4570711f0c759f591910
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI3 HNF1B ZFHX4 TOX3

2.30e-05196384c7136b1c83bcf907eec3b02b151fa061298b6672
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

CHD7 MEF2C SMAD5 TOX3

2.48e-05200384dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI3 KY TOX3

2.11e-041363837cd22169fb71c6caf9feb203ad98be8480a54fba
ToppCellControl-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

AMELY TOX MEF2C

3.28e-04158383ec425ec7b8e3c527b4bbe57908d84528b9747796
ToppCellLPS-antiTNF-Endothelial-Endothelial-FOXM1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STIL SGO1 ZGRF1

3.59e-041633835285318c52aa31c9b22dc2ffff078e32e408604d
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

3.72e-04165383eec2d327c94832d1390314c93ef6a2be4648478b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

3.72e-0416538388681101d7cf60b99b8ace5d8c0944323b937306
ToppCelldroplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL SGO1 TOX3

3.72e-0416538396f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling-Cycling_Connecting_Tubule_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

3.85e-04167383108ae6221c6edc63c0ec42c42471b3a15a594043
ToppCellCV-Mild-6|CV / Virus stimulation, Condition and Cluster

TRERF1 MAGI3 MAN2B1

3.85e-04167383cf2ed0b6d17a16f9a2318879ce8856d5983ad3cf
ToppCellMild/Remission-B_naive-4|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

USF3 CREBBP MEF2C

3.99e-04169383c3a6179a64589a370108fea809b157839347759c
ToppCellmetastatic_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

TRERF1 IL16 TOX

3.99e-04169383a4204bdd75837f5fee9aaac459cb4c19ee2a7bf4
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-FOXM1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STIL SGO1 ZGRF1

3.99e-04169383e0607af8ae8609d43e26ff2a2cab92650bfcd5b7
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

PAXIP1 STIL SGO1

4.06e-041703835319f73cff64f2bb67472c7156ee1d0f006c6fc0
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGO1 ZGRF1 AKNAD1

4.13e-04171383b92963f9f247d2e5e2e6c51c6dbf70e527cd2f55
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SGO1 ZGRF1 AKNAD1

4.13e-04171383b0373ed8283ee1792b6a490bff93906546978593
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|367C / Donor, Lineage, Cell class and subclass (all cells)

MAGI3 STIL TOX3

4.20e-04172383a9e65201ad9ab4f64251aba2c0bb3d8f9e0193b6
ToppCell367C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|367C / Donor, Lineage, Cell class and subclass (all cells)

MAGI3 STIL TOX3

4.20e-0417238326006967d0c82f7bd9b36a18e97a1b93e856aa67
ToppCell10x5'-bone_marrow-Lymphocytic_NK-Cycling_NK|bone_marrow / Manually curated celltypes from each tissue

STIL SGO1 ZGRF1

4.27e-041733838a9dd85f718564c07cf3120ad648daeb60c94fc5
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

STIL SGO1 ZGRF1

4.27e-0417338320889aa85e36ad3bafdb91b91e43964493c949f9
ToppCell10x5'-Lung-Myeloid_Dendritic-Cycling_Dendritic|Lung / Manually curated celltypes from each tissue

STIL SGO1 MEF2C

4.27e-0417338362e0c18cfed9645e34a9d7029c94a8554f773714
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

STIL SGO1 ZGRF1

4.27e-0417338346e601b7938b1dd0aa3df7aa056c4bd07b1620c1
ToppCellPND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STIL SGO1 ZGRF1

4.34e-0417438366555c610251ea04f968c258e312d720c18e7cde
ToppCellfacs-Marrow-KLS-3m-Lymphocytic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPT1B SGO1 MEF2C

4.34e-041743830cf40ce9d9ad926c4909665aaa224694b5d970cb
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STIL SGO1 ZGRF1

4.34e-0417438372df66319f6efbd88ecf439013d97409fbf3cb52
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STIL SGO1 ZGRF1

4.34e-04174383c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCellDendritic_Cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

IL16 MEF2C UBQLN3

4.41e-04175383584290a51f9975782a5ac8c6ad67c778d8323f8c
ToppCellCV-Mild-6|Mild / Virus stimulation, Condition and Cluster

MAGI3 MAN2B1 CREBBP

4.41e-04175383c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)-|368C / Donor, Lineage, Cell class and subclass (all cells)

STIL SGO1 ZGRF1

4.41e-04175383fd8b5b756f3df4a04938785f3d9edbb6f1cd20f6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling-Cycling_Distal_Convoluted_Tubule_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

4.41e-04175383876cea684faf42ff3eb4623ad6d7a1fb1276ee02
ToppCell368C-Epithelial_cells-Epithelial-J_(AT1-AT2_progenitors)|368C / Donor, Lineage, Cell class and subclass (all cells)

STIL SGO1 ZGRF1

4.41e-0417538336c140540497bbe1c5f08fac2d94f08cac18fabb
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PAXIP1 STIL SGO1

4.49e-041763838813c01ea080f373fe3970c5e1ba4c2dca0f7f02
ToppCellPND14-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

STIL TOX SGO1

4.49e-041763839e719e6323597ecfc758c957256872cd4ae24d4d
ToppCellBAL-Severe-cDC_3|Severe / Compartment, Disease Groups and Clusters

IL16 USF3 MEF2C

4.56e-04177383939487a05311b66edfc3f44a7955fbf25266d6bf
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

CHD7 TOX MEF2C

4.56e-04177383653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCell367C-Myeloid-Dendritic-cDC_proliferating_1|367C / Donor, Lineage, Cell class and subclass (all cells)

STIL SGO1 ZGRF1

4.56e-04177383ba701d3c90722d8bff70d0fa651899305cdad257
ToppCellfacs-Pancreas-Exocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAXIP1 MED15 KY

4.64e-04178383fcbbcc44271515de1969b4732b6441c012693d5f
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL SGO1 ZGRF1

4.64e-04178383de6cd81e6d58e7687386df163471bf1901b9c0aa
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

IL16 FEM1C CNOT1

4.64e-04178383c87945146b2734141f07b39d268e0d8086ee0364
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

4.72e-0417938388d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-ventral_progenitors_and_neurons_2|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

CHD7 ZFHX4 TOX3

4.72e-04179383d95367d689732ab2653e8d70d8d8e5eb15ae6eef
ToppCell390C-Lymphocytic-NK_cells-Proliferating_NK_cell|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

PAXIP1 MAGI3 SGO1

4.72e-04179383e67ad7ab04d0c1309296f57c1f53c5ca14c213fe
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

4.72e-0417938380112c686a8f85ad5e3cda6e3f3d3d51cf688092
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

4.79e-04180383401df9cddcbca1eb8f0d2687bcacd98e95dc1493
ToppCellLPS-IL1RA-Endothelial-Endothelial-FOXM1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

STIL SGO1 ZGRF1

4.79e-04180383334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

4.79e-04180383f8a15c13d85c1bbbf86ce49bb6f86c368ddf22df
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 TOX ZFHX4

4.79e-04180383da723df348d7b8449bb1124f23fe6fa706412adb
ToppCelldroplet-Lung-nan-18m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL SGO1 ZGRF1

4.79e-0418038343fd5c498a87bb078d101298b472656f3294686a
ToppCelldroplet-Heart-nan-3m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 TOX ZFHX4

4.79e-041803835b146a94708b3c3610542a4d0925f3f7a2b19185
ToppCelldroplet-Heart-nan-3m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 TOX ZFHX4

4.79e-0418038350758b1e7be2e43f83c10ab106900c067e61f5f7
ToppCellcontrol-Lymphoid-B_cell|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

IL16 TOX MEF2C

4.87e-04181383e414303bb90e5fe7b667c2acf9a50f8694b90e54
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KY STIL SGO1

4.95e-0418238339f9b3eb22293cc27c6e175702c77d1eeb24fdc9
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL SGO1 ZGRF1

4.95e-04182383fe46819c153a81911864473badc794f243705f98
ToppCelldroplet-Lung-immune-endo-depleted-3m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL SGO1 ZGRF1

4.95e-041823833948422707d6d5e021bcd7158e2eb69143613f62
ToppCelldroplet-Lung-18m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STIL SGO1 ZGRF1

5.03e-04183383e91f00b75d43ee6293fdd4a129b789cd95f8d11a
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MED15 CHD7 EMSY

5.11e-04184383a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

MED15 CHD7 EMSY

5.11e-04184383081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCellControl-Myeloid_G-immature_Neutrophil|Control / Disease group, lineage and cell class

MED15 CHD7 EMSY

5.11e-0418438345f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

TRERF1 MED15 EMSY

5.11e-04184383ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellcellseq2-Immune-Lymphocytic_B-Lymphocytic_B-B|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IL16 SGO1 MEF2C

5.11e-04184383efcd643324ccd212350dc6a27f40efbb666d557b
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

MED15 CHD7 EMSY

5.11e-0418438384c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCellControl-immature_Neutrophil-|Control / Disease condition and Cell class

MED15 CHD7 EMSY

5.11e-04184383c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
ToppCellControl-immature_Neutrophil|Control / Disease condition and Cell class

MED15 CHD7 EMSY

5.11e-041843832fdae5c6b3eb2232881d933a8c1061fda3623016
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SCAF11 MEF2C EP300

5.11e-041843831154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellPBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

MED15 CHD7 EMSY

5.11e-04184383d31d4116d1d196633784863781fa45673607a421
ToppCelldroplet-Lung-30m-Hematologic-myeloid-alveolar_macrophage-proliferating_alveolar_macrophage|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

STIL CPT1B ZGRF1

5.19e-04185383b4af9ae4c358b48357cb135b740266e1652d886a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_G2M|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

5.19e-0418538330e041d6f6e310d64809e9d6d93cd30052972f3b
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI3 TOX TOX3

5.19e-041853833d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

SCAF11 CREBBP EP300

5.27e-0418638303db813598b67b1e08f759758a1c2023396921fa
ToppCell368C-Lymphocytic-NK_cells-NK_cell_D3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

RPGR ZGRF1 SMAD5

5.36e-04187383c667fae6440dc98072b584f203d00f0fb1cb2f21
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

5.36e-041873839351fa87b69a951af85b10bf91fe9b1cce8c0517
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL TOX SGO1

5.36e-04187383a2076599b33ae6750961b573bfebcb9036fa4ee8
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL SGO1 TOX3

5.36e-041873834d12c70c8ed922fbc8f7b139145611203735cab4
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL TOX SGO1

5.36e-0418738338ee33295a21db4aae5ba085df033db9693e41c6
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell_cycling|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

5.36e-04187383057569c9437219ecc396aa6e673b1178a2273837
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL SGO1 TOX3

5.36e-04187383e851ee46a6b4068a7bd7602ee183c0ace50ee4dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL SGO1 TOX3

5.36e-04187383e46b49b4053d2d0f3e1d2bcdc380f7f8733cbe07
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL TOX SGO1

5.36e-04187383dbcec24d2c852964736c78e9d81650bff5c455ae
ToppCellCOVID-19-kidney-CD-PC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HNF1B TOX TOX3

5.44e-041883838f9996c3f3b27efaaae8960a66af77412de9c7ef
ToppCell-Unknown-Endothelial-Myofibroblast| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAXIP1 RNF38 MAGI3

5.44e-041883836468fa95ad0395395301115286f2d8c0df5d3882
ToppCell-Unknown-Endothelial| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAXIP1 RNF38 MAGI3

5.44e-041883837a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell367C-Lymphocytic-CD4_T-cell-Proliferating_T_cell|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

STIL SGO1 MEF2C

5.44e-04188383f5102e8d95506c25c675094b86162a6a50087b64
ToppCell-Unknown| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PAXIP1 RNF38 MAGI3

5.44e-041883839cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c01-TCL1A|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RPGR MAN2B1 MEF2C

5.52e-04189383b13f315f617840eb5143a4e8a33a657c20365c21
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX ZFHX4 MEF2C

5.52e-04189383fcc3713e8200d51074f709f3360fb36efb0a639f
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI3 TOX TOX3

5.52e-04189383a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Cycling_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

STIL SGO1 ZGRF1

5.61e-0419038331de1727822e9818652946dfb962daee77ffad68
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MAGI3 TOX TOX3

5.61e-04190383b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

STIL SGO1 ZGRF1

5.61e-04190383e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STIL TOX SGO1

5.69e-04191383239300ff76f2c855b2b04d3002461158be90a01b
ToppCell3'_v3-GI_small-bowel-Lymphocytic_T_CD4/8-lo-Cycling_T|GI_small-bowel / Manually curated celltypes from each tissue

STIL SGO1 ZGRF1

5.69e-04191383e642fa7395c05fb53324c9d46bbc52f89fc9673f
DrugQuinidine hydrochloride monohydrate [6151-40-2]; Down 200; 10.6uM; MCF7; HT_HG-U133A

SMURF1 RPGR CPT1B EMSY BRD4

1.33e-051953653191_DN
DrugMebendazole [31431-39-7]; Down 200; 13.6uM; MCF7; HT_HG-U133A

MED15 SMURF1 RNF38 BRD4 HPS1

1.40e-051973652300_DN
DrugAdiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; PC3; HT_HG-U133A

SMURF1 HNF1B EMSY BRD4 SMAD5

1.43e-051983657279_UP
DrugCanavanine sulfate monohydrate (L,+) [206996-57-8]; Up 200; 13.6uM; MCF7; HT_HG-U133A

SMURF1 CPT1B CREBBP MEF2C BRD4

1.43e-051983654782_UP
Drug3,4-dimethoxy-N-((2,2-dimethyl-2H-chromen-6-yl)methyl)-N-phenylbenzenesulfonamide

CREBBP EP300

2.42e-055362ctd:C575894
Drug1-chlorobutane

TRERF1 TOX

8.69e-059362CID000008005
Drug2,4,5-trichlorophenol

HNF1B TOX MEF2C

9.50e-0556363CID000007271
DrugPhenylephrine

CPT1B TOX CREBBP MEF2C EP300 BRD4

1.28e-04505366ctd:D010656
Drugdaunorubicin HCl; Up 200; 1uM; MCF7; HT_HG-U133A

HNF1B CPT1B HPS1 SMAD5

1.95e-041833647507_UP
DrugN,N-diethyl-1-phenylcyclohexylamine

KY MAN2B1

2.19e-0414362CID000604690
DrugMethotrexate [59-05-2]; Down 200; 8.8uM; PC3; HT_HG-U133A

HNF1B FEM1C EP300 BRD4

2.25e-041903646318_DN
DrugCP-690334-01 [459212-38-5]; Down 200; 10uM; PC3; HT_HG-U133A

TOX CCNK EMSY HPS1

2.29e-041913643823_DN
DrugPramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; MCF7; HT_HG-U133A

RPGR ZFHX4 HPS1 SMAD5

2.34e-041923646054_DN
DrugCefsulodin sodium salt [52152-93-9]; Down 200; 7.2uM; PC3; HT_HG-U133A

SMURF1 CPT1B EMSY BRD4

2.38e-041933644067_DN
DrugErythromycin [114-07-8]; Down 200; 5.4uM; PC3; HT_HG-U133A

SMURF1 HNF1B CPT1B HPS1

2.43e-041943646729_DN
DrugBetazole hydrochloride; Up 200; 27uM; PC3; HT_HG-U133A

CPT1B EP300 EMSY BRD4

2.43e-041943641812_UP
DrugDirithromycin [62013-04-1]; Down 200; 4.8uM; MCF7; HT_HG-U133A

MED15 EMSY HPS1 SMAD5

2.43e-041943647446_DN
DrugPhthalylsulfathiazole [85-73-4]; Down 200; 10uM; PC3; HT_HG-U133A

MED15 HNF1B BRD4 SMAD5

2.48e-041953644653_DN
DrugSTOCK1N-35874; Up 200; 14uM; PC3; HT_HG-U133A

MED15 SMURF1 EMSY HPS1

2.48e-041953646561_UP
Drug5252917; Down 200; 14uM; MCF7; HT_HG-U133A_EA

SMURF1 RPGR BRD4 SMAD5

2.48e-04195364828_DN
Drug5252917; Down 200; 14uM; MCF7; HT_HG-U133A_EA

SCAF11 RPGR HPS1 SMAD5

2.48e-04195364944_DN
DrugNaphazoline hydrochloride [550-99-2]; Down 200; 16.2uM; PC3; HG-U133A

ZNF384 HNF1B ZFHX4 ATXN2

2.48e-041953641886_DN
DrugColchicine [64-86-8]; Down 200; 10uM; PC3; HT_HG-U133A

HNF1B CPT1B BRD4 HPS1

2.48e-041953644614_DN
Drugfelodipine; Down 200; 10uM; MCF7; HT_HG-U133A_EA

MED15 SMURF1 EP300 SMAD5

2.53e-04196364848_DN
DrugBisoprolol fumarate; Down 200; 9uM; PC3; HT_HG-U133A

CPT1B TOX MEF2C HPS1

2.53e-041963646748_DN
Drugestradiol, USP; Down 200; 0.1uM; MCF7; HT_HG-U133A

MED15 RPGR CPT1B HPS1

2.53e-041963645205_DN
DrugTrimetazidine dihydrochloride [13171-25-0]; Down 200; 11.8uM; MCF7; HT_HG-U133A

SMURF1 ZNF384 CPT1B SMAD5

2.53e-041963642876_DN
DrugY-27632; Down 200; 3uM; MCF7; HT_HG-U133A_EA

SMURF1 CPT1B HPS1 SMAD5

2.53e-04196364832_DN
Drugaspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A

RPGR ZFHX4 BRD4 HPS1

2.58e-041973646964_UP
DrugN-Acetyl-L-leucine [1188-21-2]; Down 200; 23uM; PC3; HT_HG-U133A

HNF1B EMSY BRD4 HPS1

2.58e-041973644622_DN
DrugMephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A

SMURF1 RPGR FEM1C BRD4

2.58e-041973643425_DN
DrugHydroflumethiazide [135-09-1]; Up 200; 12uM; PC3; HT_HG-U133A

SMURF1 TOX EMSY BRD4

2.58e-041973647259_UP
DrugMeprylcaine hydrochloride [956-03-6]; Down 200; 14.8uM; MCF7; HT_HG-U133A

SMURF1 CNOT1 CCNK HPS1

2.58e-041973643544_DN
DrugBenzonatate [104-31-4]; Down 200; 6.6uM; PC3; HT_HG-U133A

MED15 RPGR ATXN2 HPS1

2.58e-041973641801_DN
DrugViomycin sulfate [37883-00-4]; Up 200; 5.2uM; PC3; HT_HG-U133A

CHD7 EMSY BRD4 SMAD5

2.63e-041983647278_UP
DrugTrapidil [15421-84-8]; Up 200; 19.4uM; HL60; HT_HG-U133A

HNF1B CCNK HPS1 SMAD5

2.63e-041983643136_UP
DrugLymecycline [992-21-2]; Up 200; 6.6uM; PC3; HT_HG-U133A

SMURF1 TOX CCNK MEF2C

2.63e-041983647291_UP
DrugAltretamine [654-05-6]; Down 200; 19uM; PC3; HT_HG-U133A

CHD7 ATXN2 BRD4 HPS1

2.63e-041983644627_DN
DrugPheniramine maleate [132-20-7]; Up 200; 11.2uM; PC3; HG-U133A

PAXIP1 SMURF1 CNOT1 EP300

2.63e-041983641910_UP
DrugFuraltadone hydrochloride [3759-92-0]; Down 200; 11uM; MCF7; HT_HG-U133A

SMURF1 FEM1C BRD4 HPS1

2.63e-041983643413_DN
DrugMeclofenamic acid sodium salt monohydrate [6385-02-0]; Up 200; 11.8uM; PC3; HT_HG-U133A

SMURF1 HNF1B MEF2C HPS1

2.63e-041983642128_UP
DrugPiperidolate hydrochloride [129-77-1]; Down 200; 11.2uM; MCF7; HT_HG-U133A

RPGR CCNK EMSY BRD4

2.63e-041983643551_DN
DrugTropine [120-29-6]; Down 200; 28.4uM; MCF7; HT_HG-U133A

MED15 SMURF1 HPS1 SMAD5

2.63e-041983646264_DN
DrugSerotonin hydrochloride [153-98-0]; Up 200; 18.8uM; HL60; HT_HG-U133A

SMURF1 CREBBP CCNK SMAD5

2.68e-041993642449_UP
DrugPractolol [6673-35-4]; Down 200; 15uM; PC3; HT_HG-U133A

HNF1B CHD7 BRD4 SMAD5

2.68e-041993644603_DN
DrugPrilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; PC3; HT_HG-U133A

AMELY HNF1B CCNK HPS1

2.68e-041993644284_UP
Drug2-propylpentanoic acid; Up 200; 50uM; MCF7; HT_HG-U133A

AMELY IL16 BRD4 HPS1

2.68e-041993646941_UP
DrugMethylhydantoin-5-(L) [40856-73-3]; Up 200; 35uM; MCF7; HT_HG-U133A

AMELY HNF1B IL16 CPT1B

2.73e-042003645679_UP
DrugBenoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; MCF7; HT_HG-U133A

MED15 EMSY BRD4 HPS1

2.73e-042003641476_DN
Druglactofen

HNF1B TOX MEF2C

2.85e-0481363CID000062276
DiseaseMenke-Hennekam syndrome

CREBBP EP300

1.45e-062362cv:C5681632
DiseaseRubinstein-Taybi syndrome (implicated_via_orthology)

CREBBP EP300

1.45e-062362DOID:1933 (implicated_via_orthology)
DiseaseRubinstein-Taybi syndrome

CREBBP EP300

1.45e-062362cv:C0035934
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

1.45e-062362C4551859
DiseaseRUBINSTEIN-TAYBI SYNDROME 1

CREBBP EP300

1.45e-062362180849
DiseaseRubinstein-Taybi syndrome due to CREBBP mutations

CREBBP EP300

1.45e-062362cv:C4551859
DiseaseRubinstein-Taybi syndrome (is_implicated_in)

CREBBP EP300

1.45e-062362DOID:1933 (is_implicated_in)
DiseaseRubinstein-Taybi Syndrome

CREBBP EP300

1.45e-062362C0035934
Diseaselongevity, healthspan, parental longevity

MAGI3 ATXN2 TOX3

5.96e-0629363EFO_0004300, EFO_0007796, EFO_0009762
Diseasealopecia areata

MAGI3 ATXN2 EMSY

3.14e-0550363EFO_0004192
Diseaseneutrophil percentage of granulocytes

TRERF1 CHD7 ATXN2 EMSY

1.68e-04228364EFO_0007994
Diseaseeosinophil percentage of granulocytes

TRERF1 CHD7 ATXN2 EMSY

1.86e-04234364EFO_0007996
Diseasebasophil count, eosinophil count

TRERF1 CHD7 ATXN2 EMSY

2.08e-04241364EFO_0004842, EFO_0005090
Diseaseallergic disease

SMURF1 FEM1C ATXN2 EMSY

2.70e-04258364MONDO_0005271
Diseaseautism spectrum disorder (implicated_via_orthology)

CHD7 CREBBP MEF2C

8.45e-04152363DOID:0060041 (implicated_via_orthology)
DiseaseProstatic Neoplasms

HNF1B IL16 CHD7 CREBBP BRD4

8.61e-04616365C0033578
DiseaseMalignant neoplasm of prostate

HNF1B IL16 CHD7 CREBBP BRD4

8.61e-04616365C0376358
Diseaserheumatoid arthritis, Crohn's disease

MAGI3 EMSY

9.90e-0438362EFO_0000384, EFO_0000685
DiseaseCarcinoma, Transitional Cell

CREBBP EP300

1.15e-0341362C0007138

Protein segments in the cluster

PeptideGeneStartEntry
QMAHVQIFQRPIQHQ

EP300

1941

Q09472
QQHMLPNQAQSPHLQ

EP300

2281

Q09472
QQSMTPTQHHQPNLP

AMELY

121

Q99218
HHHQQMQQAPAPVPQ

BRD4

741

O60885
PVHLQPMQFSTHIQQ

BRD4

996

O60885
GKQQMPHHTPHQLQQ

CCNK

261

O75909
PQQHMLSGQPQASHL

CREBBP

2316

Q92793
PSVQHMLQEQHNQPH

CBLL2

191

Q8N7E2
MLQEQHNQPHKDIQA

CBLL2

196

Q8N7E2
LMHQQPIHPSGSLNQ

CHD7

361

Q9P2D1
QQQHPVLHLQPQQIM

PAXIP1

411

Q6ZW49
PLHIAALNNHPDIMN

FEM1C

531

Q96JP0
LQHRPMGQSQANHIP

MAGI3

956

Q5TCQ9
HENLVEKQHPQQPQV

KY

66

Q8NBH2
PNMPQQRQDQHHQSA

ATXN2

1001

Q99700
NPEQRHHCQQTPNPM

FAM205A

381

Q6ZU69
NPEQRHHCQQTPNPM

FAM205BP

111

Q63HN1
ENHGHMPLQPNASLN

IL16

731

Q14005
PPSQALPQQLQQMHH

MED15

281

Q96RN5
QQQHLHNMPPSALSQ

MEF2C

351

Q06413
PSQQIQMEPIVHIHQ

AKNAD1

326

Q5T1N1
PTVQPNMLNVHLLPH

MAN2B1

56

O00754
HLQADQLQHKLPQMP

EMSY

981

Q7Z589
PHLPQHLQDQVQRLM

HPS1

496

Q92902
HAPLMNIQRNPFNIH

SCAF11

1236

Q99590
QSQIRMFDPEQHPNH

CPT1B

691

Q92523
QQLHSPHQQPLMQQS

HNF1B

476

P35680
NHMSQNHQNIPPTNT

RPGR

996

Q92834
LHPAAHPPQQNAVMV

RNF38

171

Q9H0F5
HPPQQNAVMVDIHDQ

RNF38

176

Q9H0F5
PLVNMHIPENVQHNA

SGO1

231

Q5FBB7
MQPKHIQAQPQHQDS

REELD1

36

A0A1B0GV85
HIMNHQCQLKEPSQP

SMURF1

341

Q9HCE7
QFRNLSHNEPHMPQN

SMAD5

156

Q99717
QHLHAIPPTLAMNPQ

CNOT1

1621

A5YKK6
EHVMQPLLHQPSDNQ

STIL

921

Q15468
HPPQSPAQIQMQLQH

ZFHX4

1641

Q86UP3
HMRKHNPPDLQQQVQ

ZNF384

451

Q8TF68
KTGQPHPHHQQMQQQ

USF3

1551

Q68DE3
LQQLQHMQHQSQPSP

TOX3

516

O15405
NMNLHIPHIQNQIAE

ZGRF1

686

Q86YA3
NHNGLLPFHPQNMDL

TOX

101

O94900
LQISPPLHQHLNMQQ

TOX

421

O94900
PLHQHLNMQQHQPLT

TOX

426

O94900
VLDNPHMQQLIQHNP

UBQLN3

191

Q9H347
LQEQQQQQMHLQPPS

TRERF1

336

Q96PN7