Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	negative regulation of protein depolymerization	MAP1A CAPZA1 SHROOM2 CRACD MID1IP1 CAMSAP2	3.70e-06	89	96	6	GO:1901880
GeneOntologyBiologicalProcess	protein depolymerization	MAP1A CAPZA1 SHROOM2 CRACD MID1IP1 MICAL2 CAMSAP2	4.96e-06	144	96	7	GO:0051261
GeneOntologyBiologicalProcess	negative regulation of protein-containing complex disassembly	MAP1A CAPZA1 SHROOM2 CRACD MID1IP1 CAMSAP2	7.27e-06	100	96	6	GO:0043242
GeneOntologyBiologicalProcess	regulation of protein depolymerization	MAP1A CAPZA1 SHROOM2 CRACD MID1IP1 CAMSAP2	9.64e-06	105	96	6	GO:1901879
GeneOntologyBiologicalProcess	negative regulation of cytoskeleton organization	MAP1A CAPZA1 SHROOM2 CRACD MID1IP1 SSH3 CAMSAP2	3.44e-05	194	96	7	GO:0051494
GeneOntologyBiologicalProcess	negative regulation of supramolecular fiber organization	MAP1A CAPZA1 SHROOM2 CRACD MID1IP1 SSH3 CAMSAP2	3.79e-05	197	96	7	GO:1902904
GeneOntologyBiologicalProcess	regulation of protein-containing complex disassembly	MAP1A CAPZA1 SHROOM2 CRACD MID1IP1 CAMSAP2	5.77e-05	144	96	6	GO:0043244
GeneOntologyCellularComponent	supramolecular fiber	ANK3 MAP1A CENPE SHROOM2 EFHC2 HABP4 MID1IP1 MICAL2 PDE4DIP IFFO2 DCTN4 CAMSAP2 PBXIP1 AHNAK2 MYBPC1	3.01e-04	1179	96	15	GO:0099512
GeneOntologyCellularComponent	supramolecular polymer	ANK3 MAP1A CENPE SHROOM2 EFHC2 HABP4 MID1IP1 MICAL2 PDE4DIP IFFO2 DCTN4 CAMSAP2 PBXIP1 AHNAK2 MYBPC1	3.23e-04	1187	96	15	GO:0099081
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	JCAD ARHGEF5 KIAA0232 LARP1 WDR59 MTMR4 TAB1 TMEM102 TNFAIP3 CAMSAP2 WNK4 GOLGB1 NOTCH2 AHNAK2	1.39e-07	861	98	14	36931259
Pubmed	Some human KIR haplotypes contain two KIR2DL5 genes: KIR2DL5A and KIR2DL5B.	KIR2DL5B KIR2DL5A	7.86e-06	2	98	2	12185535
Pubmed	Gene structure and promoter variation of expressed and nonexpressed variants of the KIR2DL5 gene.	KIR2DL5B KIR2DL5A	7.86e-06	2	98	2	11086080
Pubmed	Association of KIR2DL5B gene with celiac disease supports the susceptibility locus on 19q13.4.	KIR2DL5B KIR2DL5A	7.86e-06	2	98	2	17215859
Pubmed	FBXO6-Mediated Ubiquitination and Degradation of Ero1L Inhibits Endoplasmic Reticulum Stress-Induced Apoptosis.	ERO1A FBXO6	7.86e-06	2	98	2	27855403
Pubmed	MTHFR 677TT alone and IRF6 820GG together with MTHFR 677CT, but not MTHFR A1298C, are risks for nonsyndromic cleft lip with or without cleft palate in an Indian population.	IRF6 MTHFR	7.86e-06	2	98	2	19419265
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	SPEG WDR59 HIVEP3 SLC7A1 CELSR1 ARVCF MTHFR UNKL DLX2 TNFAIP3 ZNF579 NOTCH2 AHNAK2	1.38e-05	1105	98	13	35748872
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	SEMG1 PNMA1 ATXN7L2 MAP1A RREB1 ZNF24 SULF2 HMCN2 MTHFR NKAP ZNF579 SLC25A19 NOTCH2	1.54e-05	1116	98	13	31753913
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	AVL9 KIAA0232 SPEG SNX19 CRACD PDE4DIP KATNIP CAMSAP2	2.06e-05	407	98	8	12693553
Pubmed	WT1-dependent sulfatase expression maintains the normal glomerular filtration barrier.	WT1 SULF2	2.35e-05	3	98	2	21719793
Pubmed	Molecular Pathway of Microtubule Organization at the Golgi Apparatus.	PDE4DIP CAMSAP2	2.35e-05	3	98	2	27666745
Pubmed	Promoter variants of KIR2DL5 add to diversity and may impact gene expression.	KIR2DL5B KIR2DL5A	2.35e-05	3	98	2	18461314
Pubmed	A20 prevents obesity-induced development of cardiac dysfunction.	TAB1 TNFAIP3	2.35e-05	3	98	2	29143862
Pubmed	Deregulation of CRAD-controlled cytoskeleton initiates mucinous colorectal cancer via β-catenin.	CAPZA1 CRACD	4.70e-05	4	98	2	30361697
Pubmed	Killer-cell immunoglobulin-like receptors (KIR) in severe A (H1N1) 2009 influenza infections.	KIR2DL5B KIR2DL5A	4.70e-05	4	98	2	22652695
Pubmed	KIR2DL5, a novel killer-cell receptor with a D0-D2 configuration of Ig-like domains.	KIR2DL5B KIR2DL5A	4.70e-05	4	98	2	10820258
Pubmed	SSeCKS sequesters cyclin D1 in glomerular parietal epithelial cells and influences proliferative injury in the glomerulus.	WT1 AKAP12	4.70e-05	4	98	2	22249313
Pubmed	Investigation of killer cell immunoglobulin-like receptor (KIR) gene diversity: KIR2DL2, KIR2DL5 and KIR2DS5.	KIR2DL5B KIR2DL5A	4.70e-05	4	98	2	18498296
Pubmed	N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.	ERO1A LARP1 AKAP12 ZNF579 PBXIP1 GOLGB1 AHNAK2	7.41e-05	360	98	7	33111431
Pubmed	In vitro conversion of adult murine endothelial cells to hematopoietic stem cells.	PRDX2 DLEC1	7.82e-05	5	98	2	30429596
Pubmed	Pooled genetic analysis reveals an association of SNPs of only a few genes with risk predisposition to ischemic stroke in a Chinese population.	CELSR1 MTHFR	7.82e-05	5	98	2	25855559
Pubmed	An ankyrin-based mechanism for functional organization of dystrophin and dystroglycan.	ANK3 DCTN4	7.82e-05	5	98	2	19109891
Pubmed	The role of genetic factors in the development of hemifacial spasm: preliminary results.	FLT4 MTHFR	7.82e-05	5	98	2	18642643
Pubmed	Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.	FNDC3B DHX38 CAPZA1 PDE4DIP PBXIP1	8.26e-05	156	98	5	29961565
Pubmed	Prediction of the coding sequences of unidentified human genes. VI. The coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.	AVL9 KIAA0232 DHX38 SNX19	9.18e-05	83	98	4	9039502
Pubmed	Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.	FNDC3B ARHGEF5 TUT7 DHX38 ATL3 LARP1 SULF2 ARVCF PBXIP1	9.45e-05	650	98	9	38777146
Pubmed	Control of epigenetic states by WT1 via regulation of de novo DNA methyltransferase 3A.	WT1 SIM1	1.17e-04	6	98	2	23042785
Pubmed	Testing the association of novel meta-analysis-derived diabetes risk genes with type II diabetes and related metabolic traits in Asian Indian Sikhs.	ADAMTS9 NOTCH2	1.17e-04	6	98	2	19247373
Pubmed	SUMOylated NKAP is essential for chromosome alignment by anchoring CENP-E to kinetochores.	CENPE NKAP	1.17e-04	6	98	2	27694884
Pubmed	Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.	ADAMTS9 NOTCH2	1.17e-04	6	98	2	18567820
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	JCAD CENPE KIAA0232 TUT7 CAPZA1 IFFO2 TAB1 NKAP DCTN4 CAMSAP2	1.50e-04	853	98	10	28718761
Pubmed	IRF6 is a mediator of Notch pro-differentiation and tumour suppressive function in keratinocytes.	IRF6 NOTCH2	1.64e-04	7	98	2	21909072
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ANK3 MAP1A CAPZA1 LARP1 PRDX2 SHROOM2 CRACD ARVCF MICAL2 PDE4DIP DCTN4 CAMSAP2 PBXIP1	1.91e-04	1431	98	13	37142655
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	JCAD ANK3 CAPZA1 LARP1 ARVCF SSH3 GOLGB1 NOTCH2	2.02e-04	565	98	8	25468996
Pubmed	The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage.	WT1 NOTCH2	2.18e-04	8	98	2	19914235
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	PRUNE2 JCAD ANK3 MAP1A ARHGEF5 WT1 WNK4	2.21e-04	430	98	7	35044719
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	ANK3 ERO1A TUT7 DHX38 SHROOM2 PGGT1B AKAP12 SLC7A1 ZNF24 TNFAIP3 GOLGB1	2.42e-04	1084	98	11	11544199
Pubmed	Obesity and diabetes genes are associated with being born small for gestational age: results from the Auckland Birthweight Collaborative study.	SEC16B ADAMTS9 NOTCH2	2.64e-04	44	98	3	20712903
Pubmed	Novel meta-analysis-derived type 2 diabetes risk loci do not determine prediabetic phenotypes.	ADAMTS9 NOTCH2	2.79e-04	9	98	2	18714373
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PRUNE2 ANK3 KIAA0232 CAPZA1 BARD1 LARP1 SHROOM2 HIVEP3 SLC7A1 MICAL2 KATNIP GOLGB1 NOTCH2	2.81e-04	1489	98	13	28611215
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	ERO1A TUT7 ATL3 LARP1 WDR59 ZNF691 PDE4DIP PBXIP1 GOLGB1	2.85e-04	754	98	9	33060197
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	MAP1A DHX38 CAPZA1 LARP1 PRDX2 AKAP12 CRACD CAMSAP2 GOLGB1 AHNAK2	3.09e-04	934	98	10	33916271
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	ANK3 CAPZA1 LARP1 PRDX2 RREB1 AKAP12 EFHC2 KATNIP TMEM102 NKAP DCTN4 CAMSAP2	3.43e-04	1321	98	12	27173435
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	KCTD9 ANK3 CENPE PRDX2 AKAP12 LRIG2 ARVCF PDE4DIP CAMSAP2 GOLGB1	3.93e-04	963	98	10	28671696
Pubmed	Lack of significant effects of the type 2 diabetes susceptibility loci JAZF1, CDC123/CAMK1D, NOTCH2, ADAMTS9, THADA, and TSPAN8/LGR5 on diabetes and quantitative metabolic traits.	ADAMTS9 NOTCH2	4.25e-04	11	98	2	19670153
Pubmed	Claudin-4 localization in epithelial ovarian cancer.	AKAP12 GOLGB1 NOTCH2	4.85e-04	54	98	3	36237976
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 SEC16B DHX38 WDR59 LRIG2 HIVEP3 ADAMTS9	5.02e-04	493	98	7	15368895
Pubmed	Notch signaling promotes nephrogenesis by downregulating Six2.	WT1 NOTCH2	5.09e-04	12	98	2	27633993
Pubmed	A comprehensive SARS-CoV-2-human protein-protein interactome reveals COVID-19 pathobiology and potential host therapeutic targets.	ERO1A LARP1 AKAP12 CRACD PDE4DIP ZNF579 SLC25A19	5.66e-04	503	98	7	36217030
Pubmed	C5orf51 is a component of the MON1-CCZ1 complex and controls RAB7A localization and stability during mitophagy.	SNX19 WDR59 AKAP12 LRIG2 DCTN4 GOLGB1 NOTCH2	5.72e-04	504	98	7	34432599
Pubmed	Defects in development of the kidney, heart and eye vasculature in mice homozygous for a hypomorphic Notch2 mutation.	WT1 NOTCH2	6.01e-04	13	98	2	11171333
Pubmed	Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.	SIM1 DLX2	6.01e-04	13	98	2	8812055
Pubmed	Wnt signaling from the dorsal neural tube is required for the formation of the medial dermomyotome.	SIM1 NOTCH2	6.01e-04	13	98	2	9811581
Pubmed	Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.	KIR2DL5B KIR2DL5A	6.01e-04	13	98	2	19120281
Pubmed	Syndecan 4 controls lymphatic vasculature remodeling during mouse embryonic development.	FLT4 CELSR1	6.01e-04	13	98	2	27789626
Pubmed	A Second Heart Field-Derived Vasculogenic Niche Contributes to Cardiac Lymphatics.	FLT4 WT1	6.01e-04	13	98	2	31928974
Pubmed	Planar cell polarity genes Celsr1 and Vangl2 are necessary for kidney growth, differentiation, and rostrocaudal patterning.	WT1 CELSR1	6.01e-04	13	98	2	27597235
Pubmed	An interactome perturbation framework prioritizes damaging missense mutations for developmental disorders.	KCTD9 FNDC3B PNMA1 EFHC2 ZNF24 PDE4DIP PBXIP1	6.43e-04	514	98	7	29892012
Pubmed	Construction of a multi-functional cDNA library specific for mouse pancreatic islets and its application to microarray.	ERO1A ATL3 IRF6 RREB1 ZNF24 PDE4DIP	6.53e-04	371	98	6	15747579
Pubmed	Cardiac lymphatics are heterogeneous in origin and respond to injury.	FLT4 WT1	7.00e-04	14	98	2	25992544
Pubmed	Revisiting the role of Notch in nephron segmentation confirms a role for proximal fate selection during mouse and human nephrogenesis.	WT1 NOTCH2	7.00e-04	14	98	2	35451473
Pubmed	Bmp in podocytes is essential for normal glomerular capillary formation.	WT1 NOTCH2	7.00e-04	14	98	2	18272846
Pubmed	The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development.	WT1 NOTCH2	7.00e-04	14	98	2	23806616
Pubmed	Gene variants in the novel type 2 diabetes loci CDC123/CAMK1D, THADA, ADAMTS9, BCL11A, and MTNR1B affect different aspects of pancreatic beta-cell function.	ADAMTS9 NOTCH2	7.00e-04	14	98	2	19833888
Pubmed	β-catenin regulates the formation of multiple nephron segments in the mouse kidney.	WT1 AKAP12	8.06e-04	15	98	2	31685872
Pubmed	Mapping lineage progression of somatic progenitor cells in the mouse fetal testis.	WT1 NOTCH2	8.06e-04	15	98	2	27621062
Pubmed	The PRMT5/WDR77 complex regulates alternative splicing through ZNF326 in breast cancer.	CAPZA1 LARP1 PRDX2 ZNF579	8.13e-04	147	98	4	28977470
Pubmed	An atlas of combinatorial transcriptional regulation in mouse and man.	WT1 BARD1 IRF6 SIM1 TBX19 ZNF24 DLX2 TNFAIP3 PBXIP1	8.42e-04	877	98	9	20211142
Pubmed	Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.	SEMG1 CAPZA1 PRDX2	9.12e-04	67	98	3	29863498
Pubmed	The evolution of a genetic locus encoding small serine proteinase inhibitors.	SEMG1 WFDC3	9.19e-04	16	98	2	15950183
Pubmed	Modifier genes and protective alleles in humans and mice.	MAP1A NOTCH2	9.19e-04	16	98	2	12787792
Pubmed	[Polymorphism of killer cell immunoglobulin-like receptors gene family in Zhejiang Han population].	KIR2DL5B KIR2DL5A	9.19e-04	16	98	2	16403292
Pubmed	VEGF-C and aortic cardiomyocytes guide coronary artery stem development.	FLT4 WT1	9.19e-04	16	98	2	25271623
Pubmed	Notch2, but not Notch1, is required for proximal fate acquisition in the mammalian nephron.	WT1 NOTCH2	9.19e-04	16	98	2	17229764
Pubmed	Notch signaling is required for the formation of mesangial cells from a stromal mesenchyme precursor during kidney development.	WT1 NOTCH2	9.19e-04	16	98	2	24353058
Pubmed	Notch Dosage: Jagged1 Haploinsufficiency Is Associated With Reduced Neuronal Division and Disruption of Periglomerular Interneurons in Mice.	DLX2 NOTCH2	9.19e-04	16	98	2	32161758
Pubmed	Association of common type 2 diabetes risk gene variants and posttransplantation diabetes mellitus in renal allograft recipients in Korea.	ADAMTS9 NOTCH2	1.04e-03	17	98	2	19741467
Pubmed	Upregulation of soluble vascular endothelial growth factor receptor 1 contributes to angiogenesis defects in the placenta of alpha 2B-adrenoceptor deficient mice.	FLT4 WT1	1.04e-03	17	98	2	17673674
Pubmed	Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.	ADAMTS9 NOTCH2	1.04e-03	17	98	2	19502414
Pubmed	Association of KIR2DS1 and KIR2DS3 with fatal outcome in Ebola virus infection.	KIR2DL5B KIR2DL5A	1.04e-03	17	98	2	20878400
Pubmed	Killer cell immunoglobulin-like receptor gene diversity in the Tibetan ethnic minority group of China.	KIR2DL5B KIR2DL5A	1.04e-03	17	98	2	20650299
Pubmed	A perivascular niche for multipotent progenitors in the fetal testis.	WT1 NOTCH2	1.04e-03	17	98	2	30375389
Pubmed	Mechanisms underlying pituitary hypoplasia and failed cell specification in Lhx3-deficient mice.	TBX19 NOTCH2	1.04e-03	17	98	2	18037398
Pubmed	[Analysis of natural killer cell immunoglobulin-like receptor genes in Chinese].	KIR2DL5B KIR2DL5A	1.04e-03	17	98	2	19218127
Pubmed	Killer cell immunoglobulin-like receptor gene polymorphisms in patients with leukemia: possible association with susceptibility to the disease.	KIR2DL5B KIR2DL5A	1.04e-03	17	98	2	19450876
Pubmed	Distribution of killer-cell immunoglobulin-like receptor genes in Eastern mainland Chinese Han and Taiwanese Han populations.	KIR2DL5B KIR2DL5A	1.04e-03	17	98	2	19761533
Pubmed	A census of human transcription factors: function, expression and evolution.	WT1 IRF6 RREB1 HIVEP3 TBX19 ZNF24 UNKL DLX2 FOXL1	1.07e-03	908	98	9	19274049
Pubmed	Image-based genome-wide siRNA screen identifies selective autophagy factors.	MAP1A ITPKC CSPG5 SLC25A19	1.09e-03	159	98	4	22020285
Pubmed	Signatures of natural selection and coevolution between killer cell immunoglobulin-like receptors (KIR) and HLA class I genes.	KIR2DL5B KIR2DL5A	1.17e-03	18	98	2	20200544
Pubmed	Previously associated type 2 diabetes variants may interact with physical activity to modify the risk of impaired glucose regulation and type 2 diabetes: a study of 16,003 Swedish adults.	ADAMTS9 NOTCH2	1.17e-03	18	98	2	19324937
Pubmed	Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.	TAB1 TNFAIP3	1.17e-03	18	98	2	32968279
Pubmed	Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.	WT1 NOTCH2	1.17e-03	18	98	2	29113990
Pubmed	Negative regulation of endothelin signaling by SIX1 is required for proper maxillary development.	DLX2 NOTCH2	1.17e-03	18	98	2	28455376
Pubmed	MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate.	IRF6 MTHFR	1.17e-03	18	98	2	20572854
Pubmed	BCAR1 promotes proliferation and cell growth in lung adenocarcinoma via upregulation of POLR2A.	LRIG2 SLC7A1 ZNF24 MID1IP1 SLC25A19 GNL1	1.22e-03	419	98	6	33001583
Pubmed	Coronary arteries form by developmental reprogramming of venous cells.	FLT4 WT1	1.30e-03	19	98	2	20336138
Pubmed	Pax 2/8-regulated Gata 3 expression is necessary for morphogenesis and guidance of the nephric duct in the developing kidney.	WT1 SIM1	1.30e-03	19	98	2	16319112
Pubmed	Clinical risk factors, DNA variants, and the development of type 2 diabetes.	ADAMTS9 NOTCH2	1.30e-03	19	98	2	19020324
Pubmed	Risk prediction of prevalent diabetes in a Swiss population using a weighted genetic score--the CoLaus Study.	ADAMTS9 NOTCH2	1.30e-03	19	98	2	19139842
Pubmed	Functional proteomics mapping of a human signaling pathway.	FLT4 ANK3 MTMR4 PDE4DIP TNFAIP3 GOLGB1 NOTCH2	1.44e-03	591	98	7	15231748
Interaction	YWHAZ interactions	JCAD KCTD9 FNDC3B PNMA1 ARHGEF5 ERO1A KIAA0232 SPEG BARD1 LARP1 PRDX2 CRACD MTMR4 FBXO6 SSH3 KATNIP TAB1 TMEM102 TNFAIP3 CAMSAP2 GP5	7.98e-07	1319	96	21	int:YWHAZ
Cytoband	20q12-q13.2	SEMG1 SULF2	1.35e-05	3	98	2	20q12-q13.2
Cytoband	1p34	GJA9 HIVEP3	2.15e-03	32	98	2	1p34
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	FLT4 SPEG LRIG2 HMCN2 MYBPC1	2.26e-04	161	62	5	593
GeneFamily	CD molecules\|Killer cell immunoglobulin like receptors	KIR2DL5B KIR2DL5A	1.71e-03	18	62	2	620
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|Fibroblasts / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	PRUNE2 MAP1A ATL3 HMCN2 MICAL2 DIO2 AHNAK2	2.30e-07	196	96	7	24d64b67aa9b0e8215ad06f9101c1314b3483620
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-6_VIP_RGS16\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CRACD SULF2 HMCN2 DLX2 L3MBTL4 LINC01561	2.51e-06	179	96	6	5bf191bdc0c32bce83ab5c38f0616e209e420e55
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRUNE2 ARHGEF5 SHROOM2 ARVCF ADAMTS9 AHNAK2	3.76e-06	192	96	6	8899d81306770adda893b5e146df1253971754c5
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Epithelial-Epithelial,_Airway-secretory_cell\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	PRUNE2 ARHGEF5 SHROOM2 ARVCF ADAMTS9 AHNAK2	3.76e-06	192	96	6	5fda9a465c9f77c7fa1a3ea07a2b0374bbc23b2a
ToppCell	COVID-19_Moderate-CD4+_Tcm\|COVID-19_Moderate / disease group, cell group and cell class	ANK3 PRDX2 CD200R1 HABP4 TNFAIP3 PBXIP1	3.99e-06	194	96	6	346ab9801366501453cedd3cb7cdfb63b7e7ddf6
ToppCell	Cerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nrgn_(Inferior_colliculus)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEC16B PNMA1 ZNF831 MEIOSIN L3MBTL4	8.56e-06	128	96	5	9a800beca5cfc7b41f5eed500d45064cfa61c5de
ToppCell	Cerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6-Excitatory_Neuron.Slc17a6.Nrgn_(Inferior_colliculus)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEC16B PNMA1 ZNF831 MEIOSIN L3MBTL4	8.56e-06	128	96	5	920ede29f3de68e4d08644a1da53849e0c0973fb
ToppCell	356C-Lymphocytic-ILC-ILC-2\|356C / Donor, Lineage, Cell class and subclass (all cells)	EFHC2 TBX19 HABP4 ZNF81 PBXIP1	2.16e-05	155	96	5	0fd66c623cb433ceaa893bc21ba2e3b394faaf70
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FNDC3B SEC16B AKAP12 MEIOSIN GP5	2.44e-05	159	96	5	7ed659163f45e0c4df4782997c0786900c8186c8
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma\|TCGA-Brain / Sample_Type by Project: Shred V9	LRIG2 MTHFR PBXIP1 NOTCH2 LINC01561	2.67e-05	162	96	5	810881210e015c788814e4fe8d7a24c929cf2621
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 ZNF831 HIVEP3 SULF2 MICAL2	3.36e-05	170	96	5	6035c92cd39c5ac54e7ec57d94888ee19f574639
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 ZNF831 HIVEP3 SULF2 MICAL2	3.36e-05	170	96	5	c8c42eda44b61440c96b202e7f54650046eb95d3
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell_of_renal_medulla-lymphatic_endothelial_cell_of_renal_medulla\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FLT4 ZNF831 HIVEP3 SULF2 MICAL2	3.36e-05	170	96	5	dcc64b73134e89ae37990d4878813b86ce91dae9
ToppCell	droplet-Lung-30m-Hematologic-myeloid-classical_monocyte_proliferating-\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	KCTD9 CENPE IRF6 CELSR1 MTMR4	3.46e-05	171	96	5	1efce222989460bb59bd9fa955e7d9a60c73994c
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 RAB44 CD200R1 CRACD SULF2	3.97e-05	176	96	5	e74ad0db3b05897edcfabeb11008ede2b9eeb638
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ANK3 WT1 AKAP12 SULF2 NOTCH2	4.07e-05	177	96	5	7af1a19692f7fe8f691178a4e57d62bc379e3d56
ToppCell	droplet-Lung-3m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 RAB44 CD200R1 CRACD SULF2	4.07e-05	177	96	5	71919b5c9bfa87fdd2cd44dfa057b66ea081be5d
ToppCell	droplet-Liver-hepatocytes-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD FLT4 AKAP12 SLC25A19 ZNF287	4.07e-05	177	96	5	8ef41ee5d63737b810ad7371b0437625e7e1badf
ToppCell	TCGA-Skin-Metastatic-Melanoma-Skin_Cutaneous_Melanoma-5\|TCGA-Skin / Sample_Type by Project: Shred V9	MAP1A EFHC2 ADAMTS9 DLX2 KIAA2012	4.19e-05	178	96	5	ad5cd505ca1cef8ac29b2af7e2c3e01ebc140c14
ToppCell	5'-Adult-LymphNode-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	JCAD FLT4 AKAP12 SLC7A1 ADAMTS9	4.30e-05	179	96	5	9fd9b136ecbcbd4e4f0d5875ede98d8d48608afb
ToppCell	COVID-19-kidney-PLVAP+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JCAD FLT4 AKAP12 SULF2 ADAMTS9	4.41e-05	180	96	5	493cf8d1a8f2a1ed2672f394a0338b110fd81d88
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c08-GZMK-FOS_h\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 PRDX2 EFHC2 TNFAIP3 PBXIP1	4.41e-05	180	96	5	05f14cd367021891166825a8aac171227e2bcd97
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Pecam____fenestrated_capillary_endothelial\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SEC16B MAP1A ZNF691 AKAP12 MAJIN	4.41e-05	180	96	5	79c5725f02e038d0187f4a1e1591f2492538aa57
ToppCell	droplet-Lung-nan-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RAB44 CD200R1 CRACD SULF2	4.77e-05	183	96	5	ec3c05b9ce1e0fbb720e0dea41f1e28fd3fd878f
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WT1 CRACD SULF2 ADAMTS9 PDE4DIP	4.77e-05	183	96	5	612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WT1 CRACD SULF2 ADAMTS9 PDE4DIP	4.77e-05	183	96	5	eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SPEG AKAP12 CRACD MICAL2 FOXL1	4.77e-05	183	96	5	667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLT4 AKAP12 SLC7A1 SULF2 ADAMTS9	4.77e-05	183	96	5	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 RAB44 CD200R1 CRACD SULF2	4.90e-05	184	96	5	15ea746c77785120f69f9ab370fb7eb9b70692f8
ToppCell	droplet-Lung-21m-Hematologic-myeloid-alveolar_macrophage\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 RAB44 CD200R1 CRACD SULF2	4.90e-05	184	96	5	bd5e8fc453a6393b8778734a2c3c2f1281769bcd
ToppCell	droplet-Lung-nan-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RAB44 CD200R1 CRACD SULF2	4.90e-05	184	96	5	3261d767d5e3d9e9fbac22ad73ca14e44beed89c
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RAB44 CD200R1 CRACD SULF2	5.03e-05	185	96	5	afbb88325e4a81c15ac1d0a004e3e1f4ba2ee87b
ToppCell	droplet-Lung-immune-endo-depleted-3m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RAB44 CD200R1 CRACD SULF2	5.03e-05	185	96	5	775b72319ef6acffd2c9a74293b9c1bccea33f42
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RAB44 CD200R1 CRACD SULF2	5.16e-05	186	96	5	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 IRF6 CRACD MICAL2 WNK4	5.16e-05	186	96	5	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RAB44 CD200R1 CRACD SULF2	5.16e-05	186	96	5	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	droplet-Lung-nan-18m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RAB44 CD200R1 CRACD SULF2	5.29e-05	187	96	5	f0c6e53035b00772377c4d5f761b4d11026b911a
ToppCell	droplet-Lung-nan-18m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 RAB44 CD200R1 CRACD SULF2	5.29e-05	187	96	5	f20e7a1751694390f535ffb27b97e887220f8695
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D175\|Adult / Lineage, Cell type, age group and donor	FLT4 AKAP12 SULF2 ADAMTS9 FOXL1	5.29e-05	187	96	5	1e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PRUNE2 PNMA1 SPEG AHNAK2 L3MBTL4	5.43e-05	188	96	5	74f7d216209cabdc96b2d46685b0ae017fdcc8fc
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	FLT4 AKAP12 SLC7A1 SULF2 ADAMTS9	5.43e-05	188	96	5	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	facs-MAT-Fat-18m\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TAPBPL WT1 ZNF691 DCTN4 NOTCH2	5.43e-05	188	96	5	7f0cda7aab442aa9511d4c35569ec2389e014a71
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	PRUNE2 PNMA1 SPEG AHNAK2 L3MBTL4	5.56e-05	189	96	5	b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 RAB44 CD200R1 CRACD SULF2	5.56e-05	189	96	5	b2542b6fcf7bc10d29158d42b03182a939ff135a
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FLT4 AKAP12 SLC7A1 SULF2 ADAMTS9	5.56e-05	189	96	5	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	MatrixFB-Fibroblast-C\|MatrixFB / shred on cell class and cell subclass (v4)	WT1 AKAP12 SULF2 AHNAK2 FOXL1	5.70e-05	190	96	5	d0106f7a21292f0b96ce4337ec3efbb1bd78dd0a
ToppCell	droplet-Lung-1m-Hematologic-myeloid-alveolar_macrophage\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 RAB44 CD200R1 CRACD SULF2	5.70e-05	190	96	5	da58227565ad6a690828dd8554dd3670222f8582
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 PRDX2 CD200R1 TNFAIP3 PBXIP1	5.85e-05	191	96	5	b53b490a8796e819edd3eb4a5a42b4499077b2d3
ToppCell	COVID-19-kidney-Stressed_EC\|kidney / Disease (COVID-19 only), tissue and cell type	JCAD FLT4 ERO1A AKAP12 TNFAIP3	5.85e-05	191	96	5	d35aa842b813ea0eff7362abc894cca4e86b2fb2
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ANK3 PRDX2 ZNF831 TNFAIP3 PBXIP1	5.85e-05	191	96	5	e94dfd2d8da81bfd16f2f1a4f3ac27b078eeb3ca
ToppCell	facs-Heart-LA-3m-Endothelial-endothelial_cell_of_endocardium\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD IRF6 SHROOM2 CELSR1 WNK4	5.99e-05	192	96	5	14a816ef116aa992f86edab411f043cf7d07fe04
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-3m-Macroglial-astrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 CSPG5 DIO2 PBXIP1 NOTCH2	5.99e-05	192	96	5	261211a86e6f63b09c2ddce1d2d9257d311f1770
ToppCell	3'_v3-Lung-Lymphocytic_T_CD4\|Lung / Manually curated celltypes from each tissue	ANK3 PRDX2 ZNF831 TNFAIP3 PBXIP1	5.99e-05	192	96	5	fd19cd0b5330448bef8debd753285adbc8b958a2
ToppCell	facs-Heart-LA-3m-Endothelial-endocardial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JCAD IRF6 SHROOM2 CELSR1 WNK4	5.99e-05	192	96	5	847822514d747a21d5eb40e04ba9a023fd32bd65
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 PNMA1 AKAP12 SULF2 AHNAK2	6.14e-05	193	96	5	4aa976b596830b585e8d9c808d5072ed23d13a7c
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ERO1A TKTL1 CELSR1 HMCN2 TNFAIP3	6.14e-05	193	96	5	b93f6af5999ad207fef5edc2bd900c7c6342f626
ToppCell	5'-GW_trimst-1.5-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 PNMA1 AKAP12 SULF2 AHNAK2	6.14e-05	193	96	5	5578f7cb3ec68c9a38cc5304b618b81283024d5e
ToppCell	COVID-19_Mild-CD4+_Tcm\|COVID-19_Mild / Disease condition and Cell class	ANK3 ERO1A PRDX2 TNFAIP3 PBXIP1	6.30e-05	194	96	5	3be2b1c81e668ffdf593ff41d3ba211c26d77671
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 PNMA1 AKAP12 SULF2 AHNAK2	6.30e-05	194	96	5	12a2c60303607b8b5812405ad216d0612c56c64b
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 PNMA1 AKAP12 SULF2 AHNAK2	6.30e-05	194	96	5	15060cc25baf49dd04d9c20499e28718610ef754
ToppCell	mild_COVID-19-CD4+_Tcm\|mild_COVID-19 / disease group, cell group and cell class (v2)	ANK3 PRDX2 ZNF831 TNFAIP3 PBXIP1	6.30e-05	194	96	5	cf085813138a73878f9586059cd1d01d1a7ee748
ToppCell	(231)_CD4+/CD45RO+_Memory_T_cell\|World / immune cells in Peripheral Blood (logTPM normalization)	ANK3 PRDX2 CD200R1 TNFAIP3 PBXIP1	6.45e-05	195	96	5	af9098641bce171ed3a6ac93dbafa999460bb931
ToppCell	mild_COVID-19-CD4+_Tcm\|World / disease group, cell group and cell class (v2)	ANK3 PRDX2 ZNF831 TNFAIP3 PBXIP1	6.45e-05	195	96	5	fc666cd4d00df9cc03127fb73032ae3e46419055
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANK3 SIM1 DIO2 PBXIP1 WNK4	6.45e-05	195	96	5	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	distal-Endothelial-Lymphatic-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT4 AKAP12 SLC7A1 SULF2 ADAMTS9	6.45e-05	195	96	5	f45c1349932ee7eb419cced8a4fdedae3610953f
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 SPEG AKAP12 HMCN2 ADAMTS9	6.77e-05	197	96	5	cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCell	Parenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 SPEG AKAP12 HMCN2 ADAMTS9	6.77e-05	197	96	5	3332b9b5bf78f0203ebbd94257a36e9054d896c3
ToppCell	medial-Endothelial-Lymphatic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT4 AKAP12 SLC7A1 SULF2 ADAMTS9	6.93e-05	198	96	5	41983d405215b974044e2e9e6c212b134336a6fe
ToppCell	medial-2-Endothelial-Lymphatic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT4 AKAP12 SLC7A1 SULF2 ADAMTS9	6.93e-05	198	96	5	e4274584512a72270087a1ab104fab449a2f83bc
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_T_CD4\|lymph-node_spleen / Manually curated celltypes from each tissue	ANK3 PRDX2 ZNF831 TNFAIP3 PBXIP1	6.93e-05	198	96	5	2cbafcb03df3c9aca68371df500d18ab8dcc416c
ToppCell	medial-Endothelial-Lymphatic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	FLT4 AKAP12 SLC7A1 SULF2 ADAMTS9	6.93e-05	198	96	5	1760fede363544bc0fa2e22fe36aff522abd2525
ToppCell	Tracheal-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SEC16B ALLC AKAP12 MICAL2 DLX2	7.10e-05	199	96	5	fbec5c034576cb1adaf05f6f97cc5525d19e0c1b
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M\|organoid_Kanton_Nature / Sample Type, Dataset, Time_group, and Cell type.	KIAA0232 LRIG2 CRACD PDE4DIP DLX2	7.10e-05	199	96	5	b2d7dea11207cca63d688f8051143850b29dbdf0
ToppCell	ASK452-Endothelial\|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq	JCAD FLT4 APOL1 AKAP12 ADAMTS9	7.10e-05	199	96	5	0bc97a9a78aaafd1554ae6a61356ed9ea4983fa5
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	ANK3 HIVEP3 CRACD PDE4DIP DLX2	7.27e-05	200	96	5	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	PRUNE2 SPEG AKAP12 HMCN2 ADAMTS9	7.27e-05	200	96	5	a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCell	Bronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_endoneurial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MAP1A CSPG5 DIO2 WNK4 MYBPC1	7.27e-05	200	96	5	29054cf55e88e1ac81a562d8dd9af9b7c749321d
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)--\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CELSR1 ADAMTS9 DIO2 KIAA2012	1.05e-04	113	96	4	fed408864201218295bac0cc6647953fda8d688e
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)-\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CELSR1 ADAMTS9 DIO2 KIAA2012	1.05e-04	113	96	4	c0b8d7a2e3722029e850051bdff77f31f34a8cca
ToppCell	Cerebellum-Macroglia-ASTROCYTE-Gja1-Gfap+_astrocytes_(Gfap)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	CELSR1 ADAMTS9 DIO2 KIAA2012	1.05e-04	113	96	4	7e24c0f6a80e10a2a41325d48a87628bd330a1e2
ToppCell	Cerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEC16B ZNF831 MEIOSIN L3MBTL4	1.80e-04	130	96	4	ab141d91988a5de6d092757377a53f7de3707556
ToppCell	Cerebellum-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a6\|Cerebellum / BrainAtlas - Mouse McCarroll V32	SEC16B ZNF831 MEIOSIN L3MBTL4	1.80e-04	130	96	4	3d81151ee1369d819843826fc6ac197d83255e1d
ToppCell	PBMC-Mild-cDC_2\|Mild / Compartment, Disease Groups and Clusters	TKTL1 ZNF831 CRACD AHNAK2	2.08e-04	135	96	4	cb9d834f8301cf53f20e09c3f4cb6a148690196a
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CENPE CELSR1 TMEM102 AHNAK2	2.26e-04	138	96	4	611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TKTL1 HIVEP3 MEIOSIN MYBPC1	2.80e-04	146	96	4	86cddd0e7f954547b7ffdccb0329cd5c4b725ac1
ToppCell	Pericytes-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	SPEG AKAP12 ARVCF MICAL2	3.11e-04	150	96	4	dbc202bd6db4fb5c8b2abd1200e074a2a9e63a59
ToppCell	COVID-19_Mild\|World / 5 Neutrophil clusters in COVID-19 patients	ANK3 MAP1A TUT7 CELSR1	3.27e-04	152	96	4	2ff0980dfd8d430cca14649151d856edef115720
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PRUNE2 SPEG MEIOSIN WNK4	3.35e-04	153	96	4	1524557514668f515ac1bbe847611f564b265b42
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Neuronal-Interneuron\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	CRACD PDE4DIP DLX2	3.41e-04	63	96	3	c10d344bf32a091deb79e1f128f7dd5e9f4abaa3
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ATXN7L2 PGGT1B KATNIP L3MBTL4	3.43e-04	154	96	4	ba55a63cfa5e0fb9dfec794f80078a2f0d03d0ad
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high\|E18.5-samps / Age Group, Lineage, Cell class and subclass	PRUNE2 FLT4 WT1 RAB44	3.43e-04	154	96	4	212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 JCAD SPEG AHNAK2	3.43e-04	154	96	4	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	Club-club-7\|World / Class top	PNMA1 MAP1A UNKL	3.57e-04	64	96	3	df413c5328966480479c41826461c4d817fbe33d
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-Tfh\|Liver / Manually curated celltypes from each tissue	ANK3 MAP1A AKAP12 CAMSAP2	3.61e-04	156	96	4	85bc34ff507f9a66c6e3ba7a3ffd5416d0073ccf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 WT1 AKAP12 FOXL1	3.78e-04	158	96	4	e7db0ee4740e3c7a4d97d7cd7462e2c2ab458a4b
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TKTL1 ZNF691 HIVEP3 MYBPC1	3.78e-04	158	96	4	7f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-parietal_epithelial_cell-Parietal_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 WT1 AKAP12 FOXL1	3.78e-04	158	96	4	d39e020c3e77eb9d3de600a171d22f94357061d4
ToppCell	droplet-Limb_Muscle-nan-24m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DHX38 HIVEP3 CRACD TAB1	3.97e-04	160	96	4	984990be02642a562f0c60ea99c01f005e7c02c2
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg-Treg_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CAPZA1 TNFAIP3 L3MBTL4 GP5	3.97e-04	160	96	4	8308ca6f37986c526432a0fbc5f7ec2e75cfb6d7
ToppCell	PND07-28-samps-Myeloid-Macrophage-macrophage-B\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	RAB44 CD200R1 CRACD SULF2	3.97e-04	160	96	4	694bf1f1952bd8ab444819f533da24fa2b73f701
Drug	Bepridil hydrochloride [74764-40-2]; Up 200; 10uM; MCF7; HT_HG-U133A	PRUNE2 SPEG WDR59 HIVEP3 SLC7A1 PDE4DIP DLX2 TNFAIP3	1.56e-06	190	97	8	2629_UP
Drug	Methionine sulfoximine (L) [15985-39-4]; Down 200; 22.2uM; HL60; HT_HG-U133A	FLT4 TAPBPL PRDX2 PGGT1B WDR59 SLC7A1 CELSR1 CAMSAP2	1.89e-06	195	97	8	2470_DN
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A SPEG AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	9.36e-06	173	97	7	5625_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	9.36e-06	173	97	7	4112_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	9.72e-06	174	97	7	5260_UP
Drug	trichostatin A ; Up 200; 1uM; MCF7; HT_HG-U133A_EA	MAP1A IRF6 AKAP12 PDE4DIP DLX2 TNFAIP3 AHNAK2	1.13e-05	178	97	7	873_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A SPEG AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.13e-05	178	97	7	6454_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	IRF6 AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.17e-05	179	97	7	7005_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.21e-05	180	97	7	6064_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.21e-05	180	97	7	7236_UP
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 HABP4 PDE4DIP DLX2 PBXIP1 AHNAK2	1.50e-05	186	97	7	6891_UP
Drug	Chlorprothixene hydrochloride [6469-93-8]; Up 200; 11.4uM; MCF7; HT_HG-U133A	IRF6 HIVEP3 HABP4 PDE4DIP DLX2 TAB1 TNFAIP3	1.78e-05	191	97	7	2627_UP
Drug	rapamycin; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	PRDX2 TBX19 KATNIP TAB1 PBXIP1 AHNAK2 FOXL1	1.90e-05	193	97	7	921_UP
Drug	Bretylium tosylate [61-75-6]; Down 200; 9.6uM; MCF7; HT_HG-U133A	SPEG PRDX2 TBX19 HABP4 MTHFR TAB1 AHNAK2	2.17e-05	197	97	7	3394_DN
Drug	Acetaminophen [103-90-2]; Down 200; 26.4uM; MCF7; HT_HG-U133A	SPEG HABP4 ZNF24 ARVCF UNKL TNFAIP3 AHNAK2	2.17e-05	197	97	7	3364_DN
Drug	Mepenzolate bromide [76-90-4]; Down 200; 9.6uM; PC3; HT_HG-U133A	JCAD WDR59 HIVEP3 SLC7A1 TAB1 CAMSAP2 PBXIP1	2.17e-05	197	97	7	3748_DN
Drug	valdecoxib; Down 200; 10uM; PC3; HT_HG-U133A	JCAD FLT4 PGGT1B SLC7A1 MICAL2 PDE4DIP GP5	2.17e-05	197	97	7	6408_DN
Drug	Ajmalicine hydrochloride [4373-34-6]; Down 200; 10.2uM; MCF7; HT_HG-U133A	TBX19 SLC7A1 HABP4 ZNF24 PDE4DIP DLX2 ZNF287	2.24e-05	198	97	7	2898_DN
Drug	Acetazolamide [59-66-5]; Up 200; 18uM; HL60; HT_HG-U133A	ANK3 PRDX2 SLC7A1 MTHFR PDE4DIP SLC38A7 CAMSAP2	2.24e-05	198	97	7	1850_UP
Drug	Bemegride [64-65-3]; Down 200; 25.8uM; PC3; HT_HG-U133A	KIAA0232 PGGT1B HIVEP3 MTHFR SSH3 PDE4DIP ZNF287	2.24e-05	198	97	7	6668_DN
Drug	17-AAG; Up 200; 1uM; MCF7; HT_HG-U133A_EA	FNDC3B ANK3 ERO1A SLC7A1 ZNF24 UNKL	9.54e-05	172	97	6	1064_UP
Drug	Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.02e-04	174	97	6	5572_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	IRF6 AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.02e-04	174	97	6	7179_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP TNFAIP3 PBXIP1 AHNAK2	1.02e-04	174	97	6	6085_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.05e-04	175	97	6	3243_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.05e-04	175	97	6	4153_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.05e-04	175	97	6	5417_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.05e-04	175	97	6	2268_UP
Drug	Rifabutin [72559-06-9]; Up 200; 4.8uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.05e-04	175	97	6	3873_UP
Drug	Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A_EA	AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.08e-04	176	97	6	992_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.08e-04	176	97	6	6820_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.12e-04	177	97	6	4768_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.15e-04	178	97	6	4388_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A IRF6 PDE4DIP DLX2 PBXIP1 AHNAK2	1.19e-04	179	97	6	2794_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	IRF6 AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.19e-04	179	97	6	5336_UP
Drug	Trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A	IRF6 AKAP12 PDE4DIP TNFAIP3 PBXIP1 AHNAK2	1.19e-04	179	97	6	6993_UP
Drug	SAHA; Up 200; 10uM; MCF7; HT_HG-U133A	MAP1A IRF6 AKAP12 PDE4DIP DLX2 AHNAK2	1.22e-04	180	97	6	6939_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A	MAP1A IRF6 EFHC2 PDE4DIP TNFAIP3 AHNAK2	1.22e-04	180	97	6	4344_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	IRF6 AKAP12 DLX2 TNFAIP3 PBXIP1 AHNAK2	1.22e-04	180	97	6	7407_UP
Drug	Trichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	AKAP12 PDE4DIP DLX2 TNFAIP3 PBXIP1 AHNAK2	1.26e-04	181	97	6	5987_UP
Drug	Tamoxifen citrate [54965-24-1]; Up 200; 7uM; MCF7; HT_HG-U133A	ERO1A TKTL1 MTHFR DLX2 TNFAIP3 ZNF287	1.26e-04	181	97	6	2212_UP
Drug	Trichostatin A, Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A	MAP1A IRF6 PDE4DIP DLX2 PBXIP1 AHNAK2	1.42e-04	185	97	6	1637_UP
Drug	(1-[(4-Chlorophenyl)phenyl-methyl]-4-methylpiperazine) [1620-21-9]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ALLC ARVCF PDE4DIP DLX2 TNFAIP3 PBXIP1	1.42e-04	185	97	6	3893_UP
Drug	trichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A	MAP1A AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.42e-04	185	97	6	6916_UP
Drug	trichostatin A; Up 200; 0.1uM; MCF7; HG-U133A	TUT7 AKAP12 PDE4DIP DLX2 PBXIP1 AHNAK2	1.46e-04	186	97	6	332_UP
Drug	Withaferin A [5119-48-2]; Down 200; 1uM; MCF7; HT_HG-U133A	AKAP12 HIVEP3 PDE4DIP DLX2 TNFAIP3 PBXIP1	1.46e-04	186	97	6	3902_DN
Drug	Nocodazole [31430-18-9]; Up 200; 13.2uM; PC3; HT_HG-U133A	WT1 WDR59 ITPKC UNKL TNFAIP3 PBXIP1	1.64e-04	190	97	6	7145_UP
Drug	Digoxin [20830-75-5]; Down 200; 5.2uM; PC3; HT_HG-U133A	JCAD MAP1A PRDX2 SHROOM2 MTMR4 SSH3	1.69e-04	191	97	6	6724_DN
Drug	5253409; Up 200; 17uM; MCF7; HT_HG-U133A_EA	IRF6 SLC7A1 PDE4DIP DLX2 TNFAIP3 NOTCH2	1.69e-04	191	97	6	844_UP
Drug	Ethopropazine hydrochloride [1094-08-2]; Up 200; 11.4uM; MCF7; HT_HG-U133A	HIVEP3 SLC7A1 ITPKC ZNF24 TNFAIP3 PBXIP1	1.69e-04	191	97	6	5296_UP
Drug	Proglumide [6620-60-6]; Up 200; 12uM; MCF7; HT_HG-U133A	PRUNE2 JCAD SPEG SLC7A1 MICAL2 GP5	1.69e-04	191	97	6	3861_UP
Drug	Chelidonine monohydrate (+) [476-32-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A	AVL9 AKAP12 LRIG2 SLC7A1 ZNF24 MTMR4	1.84e-04	194	97	6	2779_DN
Drug	5211181; Up 200; 12uM; MCF7; HT_HG-U133A_EA	ANK3 HABP4 MTHFR PDE4DIP SLC38A7 TNFAIP3	1.89e-04	195	97	6	834_UP
Drug	Thiamphenicol [15318-45-3]; Up 200; 11.2uM; MCF7; HT_HG-U133A	ANK3 AKAP12 SLC7A1 MICAL2 SSH3 SLC38A7	1.89e-04	195	97	6	7033_UP
Drug	Lisuride (S)(-) [18016-80-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A	PRUNE2 JCAD IRF6 TAB1 TNFAIP3 ZNF287	1.89e-04	195	97	6	5028_UP
Drug	Tiapride hydrochloride [51012-33-0]; Down 200; 11uM; MCF7; HT_HG-U133A	FLT4 ANK3 PRDX2 SLC7A1 HABP4 SSH3	1.89e-04	195	97	6	4686_DN
Drug	Sulfachloropyridazine [80-32-0]; Down 200; 14uM; PC3; HT_HG-U133A	FLT4 TBX19 MID1IP1 SSH3 PDE4DIP TAB1	1.89e-04	195	97	6	4326_DN
Drug	Brinzolamide [138890-62-7]; Up 200; 10.4uM; PC3; HT_HG-U133A	TAPBPL WDR59 DLX2 PBXIP1 NOTCH2 GP5	1.94e-04	196	97	6	6670_UP
Drug	Pargyline hydrochloride [306-07-0]; Up 200; 20.4uM; PC3; HT_HG-U133A	MAP1A EFHC2 TBX19 ARVCF TAB1 TNFAIP3	1.94e-04	196	97	6	2102_UP
Drug	Ribostamycin sulfate salt [53797-35-6]; Down 200; 7.2uM; PC3; HT_HG-U133A	JCAD SNX19 CELSR1 PDE4DIP UNKL KATNIP	1.94e-04	196	97	6	7123_DN
Drug	Pentylenetetrazole [54-95-5]; Down 200; 29uM; PC3; HT_HG-U133A	AVL9 KIAA0232 PRDX2 MID1IP1 SSH3 PDE4DIP	2.00e-04	197	97	6	2092_DN
Drug	Metanephrine hydrochloride DL [881-95-8]; Up 200; 17.2uM; PC3; HG-U133A	KIAA0232 PRDX2 AKAP12 ZNF24 SSH3 SLC38A7	2.00e-04	197	97	6	1933_UP
Drug	15(S)-15-methyl Prostaglandin E2; Up 200; 10uM; MCF7; HT_HG-U133A	ANK3 MAP1A AKAP12 HIVEP3 DLX2 GP5	2.00e-04	197	97	6	7521_UP
Drug	Benfluorex hydrochloride [23642-66-2]; Down 200; 10.4uM; PC3; HT_HG-U133A	FLT4 SPEG PRDX2 WDR59 MICAL2 UNKL	2.00e-04	197	97	6	6727_DN
Drug	Phthalylsulfathiazole [85-73-4]; Up 200; 10uM; MCF7; HT_HG-U133A	MAP1A HIVEP3 SLC7A1 ARVCF ADAMTS9 MTHFR	2.00e-04	197	97	6	5249_UP
Drug	Pyrithyldione [77-04-3]; Up 200; 24uM; MCF7; HT_HG-U133A	HIVEP3 ZNF24 MICAL2 PDE4DIP TNFAIP3 ZNF287	2.00e-04	197	97	6	6801_UP
Drug	Tenoxicam [59804-37-4]; Up 200; 11.8uM; MCF7; HT_HG-U133A	FLT4 HIVEP3 MID1IP1 SSH3 TAB1 TNFAIP3	2.00e-04	197	97	6	2860_UP
Drug	Memantine Hydrochloride [41100-52-1]; Up 200; 18.6uM; MCF7; HT_HG-U133A	MTHFR MICAL2 PDE4DIP DLEC1 PBXIP1 AHNAK2	2.00e-04	197	97	6	4135_UP
Drug	Benoxinate hydrochloride [5987-82-6]; Down 200; 11.6uM; PC3; HT_HG-U133A	MAP1A SPEG SLC7A1 SLC38A7 DLX2 NOTCH2	2.00e-04	197	97	6	3996_DN
Drug	Oxymetazoline hydrochloride [2315-02-8]; Up 200; 13.4uM; HL60; HG-U133A	ERO1A WT1 SLC7A1 MTMR4 ARVCF PBXIP1	2.05e-04	198	97	6	1431_UP
Drug	Sulfamethizole [144-82-1]; Down 200; 14.8uM; PC3; HT_HG-U133A	AVL9 EFHC2 HIVEP3 SLC7A1 SLC38A7 TAB1	2.05e-04	198	97	6	5798_DN
Drug	Hyoscyamine (L) [101-31-5]; Down 200; 13.8uM; PC3; HT_HG-U133A	PRDX2 HIVEP3 MTHFR PDE4DIP UNKL TNFAIP3	2.05e-04	198	97	6	5099_DN
Drug	Evoxine [522-11-2]; Down 200; 11.6uM; PC3; HT_HG-U133A	JCAD KIAA0232 PRDX2 HIVEP3 PDE4DIP TNFAIP3	2.05e-04	198	97	6	3681_DN
Drug	Flucytosine [2022-85-7]; Up 200; 31uM; MCF7; HT_HG-U133A	FLT4 LRIG2 SLC7A1 PDE4DIP TNFAIP3 PBXIP1	2.05e-04	198	97	6	5289_UP
Drug	AG-013608 [351320-38-2]; Up 200; 10uM; MCF7; HT_HG-U133A	MAP1A TAPBPL SLC7A1 CELSR1 PBXIP1 GP5	2.05e-04	198	97	6	6395_UP
Drug	Nitrarine dihydrochloride [20069-05-0]; Down 200; 10.6uM; MCF7; HT_HG-U133A	WDR59 TBX19 SLC7A1 ARVCF SSH3 NOTCH2	2.05e-04	198	97	6	4705_DN
Drug	Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A	AKAP12 SLC7A1 ITPKC PDE4DIP SLC38A7 CAMSAP2	2.05e-04	198	97	6	7018_UP
Drug	Benzthiazide [91-33-8]; Down 200; 9.2uM; HL60; HT_HG-U133A	PRUNE2 ANK3 SLC7A1 MTHFR CAMSAP2 PBXIP1	2.05e-04	198	97	6	2989_DN
Drug	Niridazole [61-57-4]; Up 200; 18.6uM; PC3; HT_HG-U133A	FLT4 WT1 SLC7A1 PDE4DIP DLX2 ZNF81	2.05e-04	198	97	6	4621_UP
Drug	Ioversol [87771-40-2]; Up 200; 5uM; MCF7; HT_HG-U133A	JCAD MAP1A HIVEP3 ARVCF PDE4DIP PBXIP1	2.05e-04	198	97	6	5326_UP
Drug	Ginkgolide A [15291-75-5]; Up 200; 9.8uM; MCF7; HT_HG-U133A	FLT4 ANK3 MAP1A TKTL1 WDR59 PBXIP1	2.05e-04	198	97	6	3260_UP
Drug	Propranolol hydrochloride [318-98-9]; Down 200; 13.6uM; PC3; HT_HG-U133A	FLT4 WT1 SLC7A1 MICAL2 TAB1 ZNF287	2.11e-04	199	97	6	6759_DN
Drug	Buspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; PC3; HT_HG-U133A	FLT4 MAP1A SLC7A1 MICAL2 NOTCH2 ZNF287	2.11e-04	199	97	6	6743_DN
Drug	LY 294002; Down 200; 0.1uM; HL60; HT_HG-U133A	FLT4 ANK3 TAPBPL SLC7A1 SSH3 PBXIP1	2.11e-04	199	97	6	2676_DN
Drug	Citalopram hydrobromide [59729-32-7]; Down 200; 1uM; PC3; HT_HG-U133A	WDR59 ITPKC SSH3 TAB1 PBXIP1 NOTCH2	2.11e-04	199	97	6	4555_DN
Drug	Isoniazid [54-85-3]; Down 200; 29.2uM; PC3; HT_HG-U133A	MAP1A SPEG LARP1 SSH3 PDE4DIP SLC38A7	2.11e-04	199	97	6	2083_DN
Drug	PNU-0230031 [267429-39-0]; Up 200; 1uM; PC3; HT_HG-U133A	ANK3 ZNF24 SSH3 PDE4DIP UNKL ZNF287	2.17e-04	200	97	6	3735_UP
Drug	Ifenprodil tartrate [23210-58-4]; Up 200; 8.4uM; MCF7; HT_HG-U133A	PRDX2 PGGT1B TBX19 ARVCF TAB1 TNFAIP3	2.17e-04	200	97	6	7404_UP
Drug	Edrophonium chloride [116-38-1]; Down 200; 19.8uM; MCF7; HT_HG-U133A	FLT4 TBX19 HABP4 ZNF24 SSH3 PDE4DIP	2.17e-04	200	97	6	1519_DN
Drug	Iodipamide [606-17-7]; Up 200; 3.6uM; HL60; HT_HG-U133A	SPEG CELSR1 MTHFR MICAL2 PDE4DIP PBXIP1	2.17e-04	200	97	6	3111_UP
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; MCF7; HT_HG-U133A	ALLC IRF6 HIVEP3 HABP4 ADAMTS9 PDE4DIP	2.17e-04	200	97	6	2633_UP
Drug	Pentoxifylline [6493-05-6]; Up 200; 14.4uM; PC3; HT_HG-U133A	KIAA0232 PRDX2 SLC7A1 TAB1 TNFAIP3 PBXIP1	2.17e-04	200	97	6	2127_UP
Disease	platelet component distribution width	PRUNE2 JCAD FLT4 KIAA0232 PRDX2 ZNF831 HABP4 ARVCF DLEC1 MYBPC1 GP5	3.50e-05	755	96	11	EFO_0007984
Disease	hypertension, pregnancy-induced	ZNF831 MTHFR	1.04e-04	5	96	2	MONDO_0024664
Disease	Milroy Disease	FLT4 CELSR1	1.04e-04	5	96	2	C1704423
Disease	Malignant neoplasm of breast	FNDC3B WT1 BARD1 SIM1 APOL1 SHROOM2 AKAP12 SULF2 MTHFR DLEC1 GOLGB1 NOTCH2	1.91e-04	1074	96	12	C0006142
Disease	aspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement	FNDC3B SEC16B SIM1 SNX19 HIVEP3 SULF2 KIAA2012	1.91e-04	364	96	7	EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Disease	cathepsin Z measurement	ZNF831 MYBPC1	2.90e-04	8	96	2	EFO_0008074
Disease	Lymphoma	MTHFR TNFAIP3 NOTCH2	3.02e-04	40	96	3	C0024299
Disease	22q11 partial monosomy syndrome	RREB1 ARVCF	3.72e-04	9	96	2	C3266101
Disease	Asymmetric crying face association	RREB1 ARVCF	4.63e-04	10	96	2	C0431406
Disease	22q11 Deletion Syndrome	RREB1 ARVCF	4.63e-04	10	96	2	C2936346
Disease	Hereditary Nephrotic Syndromes, Autosomal Dominant	WT1 APOL1	5.65e-04	11	96	2	cv:CN043612
Disease	Familial idiopathic steroid-resistant nephrotic syndrome	WT1 APOL1	7.98e-04	13	96	2	cv:C4273714
Disease	nephroblastoma (is_implicated_in)	WT1 MTHFR	9.29e-04	14	96	2	DOID:2154 (is_implicated_in)
Disease	chronic kidney disease (is_implicated_in)	AKAP12 MTHFR	9.29e-04	14	96	2	DOID:784 (is_implicated_in)
Disease	Lymphoma, Large-Cell, Follicular	MTHFR TNFAIP3	1.07e-03	15	96	2	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	MTHFR TNFAIP3	1.07e-03	15	96	2	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	MTHFR TNFAIP3	1.07e-03	15	96	2	C0079758
Disease	cleft lip (is_implicated_in)	IRF6 MTHFR	1.07e-03	15	96	2	DOID:9296 (is_implicated_in)
Disease	Lymphoma, Follicular, Grade 2	MTHFR TNFAIP3	1.07e-03	15	96	2	C1956132
Disease	Lymphoma, Follicular, Grade 3	MTHFR TNFAIP3	1.07e-03	15	96	2	C1956131
Disease	Lymphoma, Follicular, Grade 1	MTHFR TNFAIP3	1.07e-03	15	96	2	C1956130
Disease	inherited metabolic disorder (is_implicated_in)	TBX19 SLC25A19	1.07e-03	15	96	2	DOID:655 (is_implicated_in)
Disease	body fat percentage	FNDC3B SEC16B SIM1 SNX19 HIVEP3 SULF2 KIAA2012	1.09e-03	488	96	7	EFO_0007800
Disease	DiGeorge Syndrome	RREB1 ARVCF	1.22e-03	16	96	2	C0012236
Disease	preeclampsia, hypertension, pregnancy-induced	ZNF831 MTHFR	1.22e-03	16	96	2	EFO_0000668, MONDO_0024664
Disease	CONOTRUNCAL ANOMALY FACE SYNDROME	RREB1 ARVCF	1.22e-03	16	96	2	C0795907
Disease	pancreatitis	JCAD MYBPC1	1.22e-03	16	96	2	EFO_0000278
Disease	Shprintzen syndrome	RREB1 ARVCF	1.22e-03	16	96	2	C0220704
Disease	intraocular pressure measurement	JCAD FNDC3B ALLC CAPZA1 EFHC2 HIVEP3 DLEC1	1.39e-03	509	96	7	EFO_0004695
Disease	Down Syndrome, Partial Trisomy 21	PRDX2 MTHFR	1.73e-03	19	96	2	C0432416
Disease	Trisomy 21, Meiotic Nondisjunction	PRDX2 MTHFR	1.73e-03	19	96	2	C0432417
Disease	Trisomy 21, Mitotic Nondisjunction	PRDX2 MTHFR	1.73e-03	19	96	2	C0751081
Disease	Down Syndrome	PRDX2 MTHFR	1.73e-03	19	96	2	C0013080
Disease	coronary artery disease	JCAD FNDC3B DHX38 WT1 ZNF831 AKAP12 CRACD ARVCF MTHFR DLEC1 FOXL1	1.73e-03	1194	96	11	EFO_0001645
Disease	neutrophil count	PRUNE2 JCAD CAPZA1 RREB1 AKAP12 LRIG2 HIVEP3 TBX19 ARVCF MICAL2 TNFAIP3 NOTCH2	1.75e-03	1382	96	12	EFO_0004833
Disease	Lung Neoplasms	ANK3 WT1 PGGT1B MTHFR NOTCH2	1.77e-03	265	96	5	C0024121
Disease	Malignant neoplasm of lung	ANK3 WT1 PGGT1B MTHFR NOTCH2	1.80e-03	266	96	5	C0242379
Disease	Lymphoma, Follicular	MTHFR TNFAIP3	1.92e-03	20	96	2	C0024301
Disease	waist-hip ratio	PRUNE2 JCAD FNDC3B SEC16B ANK3 WT1 SIM1 RREB1 ADAMTS9 DLEC1 TAB1	2.13e-03	1226	96	11	EFO_0004343
Disease	Inguinal hernia	KCTD9 CAPZA1 WT1 RREB1 HMCN2	2.50e-03	287	96	5	HP_0000023
Disease	apolipoprotein L1 measurement	DHX38 APOL1	2.99e-03	25	96	2	EFO_0021854
Disease	brain cancer (implicated_via_orthology)	NOTCH2 L3MBTL4	3.24e-03	26	96	2	DOID:1319 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
PHSGWEREPNEDSKP	ARVCF	496	O00192
GSDPNVKDHAGWTPL	BARD1	451	Q99728
ENHPDTEGETPSWSL	CSPG5	236	O95196
GTGQKDWTATDPKEP	ALLC	181	Q8N6M5
HSTPDTEPGKEESWV	AKAP12	791	Q02952
SDPQPEEADGGLKSW	CAPZA1	106	P52907
WTPELQGPTSKDEAG	ARHGEF5	941	Q12774
EEKWDPARGAVHSTP	CELSR1	2836	Q9NYQ6
WKSGEIPSEQHPGAS	DLX2	211	Q07687
WKVESLPGAHGTDFP	FBXO6	111	Q9NRD1
SSHWAEGSPPEKEPS	ATXN7L2	206	Q5T6C5
QIQASDPDDKGPGSW	RAB44	521	Q7Z6P3
GPWTELETHGSQTQP	ITPKC	171	Q96DU7
THEGGQDKPLLSAWP	KIR2DL5A	21	Q8N109
GTGTSEHWVDDEGPQ	NOTCH2	1751	Q04721
GDAINWPTPGEIAHK	LARP1	171	Q6PKG0
IDVTWHPAGDPGSDK	MTHFR	91	P42898
IDEAHPSDGWAIPGD	DIO2	161	Q92813
DSKPPEGLLGFHTDW	KCTD9	76	Q7L273
PSPKESGRSHWDDST	MAP1A	2091	P78559
PPAGSEEGSAWKSKD	MID1IP1	111	Q9NPA3
DVQKQDSEWGHSLPG	MAJIN	121	Q3KP22
VHAPPTIWGSNETGE	HMCN2	1526	Q8NDA2
PPSSGDWTQKDVHGE	KATNIP	231	O60303
SKSESWSEELQPGHP	JCAD	911	Q9P266
PLWNEHDGTADGDKP	KIAA1109	3136	Q2LD37
WGSGKDTSDVEPTAP	HABP4	241	Q5JVS0
THEGGQDKPLLSAWP	KIR2DL5B	21	Q8NHK3
PKGDGSDVPSWVAFD	EFHC2	61	Q5JST6
NSDGEWAVVPPSHTK	KIAA0232	941	Q92628
KGVWKGDDDAPPHDV	KIAA2012	521	Q0VF49
AGSPDIHPVGWCEKT	L3MBTL4	131	Q8NA19
AGKPAAHISWIPEGD	CD200R1	171	Q8TD46
PGYSEQKGTWESHPE	GNL1	521	P36915
PQIDVWSGTGHPSEI	MEIOSIN	346	C9JSJ3
DEHGEVCPAGWKPGS	PRDX2	166	P32119
PWHSNPEGSETSFVD	MTMR4	646	Q9NYA4
GWEDSQKPSVPSHGP	GUCA1ANB	16	X6R8D5
QHTPWADGTECEPGK	ADAMTS9	556	Q9P2N4
WGSSTEHENRGSPPK	GJA9	426	P57773
SHGFSVKWDPPKDNG	FNDC3B	586	Q53EP0
PGDGHDSHTLPEEWK	AVL9	41	Q8NBF6
QNGHPGEDKPTWHEE	CRACD	196	Q6ZU35
SPKSDKGHSPEDDWI	ANK3	1976	Q12955
GTDTGDPQSKPLGDW	APOL1	41	O14791
SQKESGHSNWLGDPE	ATL3	86	Q6DD88
WLLSSGHGEEQPPET	ERO1A	16	Q96HE7
ETVQGPGVSWVHPDG	IFFO2	176	Q5TF58
LHWPGTASPNEDAGD	FOXL1	206	Q12952
WAQPVTTGKGQDHSP	GP5	506	P40197
KSVASGGWQEPENPH	DCTN4	126	Q9UJW0
KESSDCSTEQWPGHP	DLEC1	1081	Q9Y238
GPGEETFDPWLEHTN	PNMA1	171	Q8ND90
HTVEAPGGQKSPSKW	CAMSAP2	206	Q08AD1
GAESVDSQPGPWHAS	CENPE	2676	Q02224
DSQPGPWHASSGKDV	CENPE	2681	Q02224
GSEGSHTEPCEEKPW	MICAL2	1181	O94851
WGLSPKNPEPDSDEH	NKAP	146	Q8N5F7
PGSTGSAPWDEKDND	IRF6	126	O14896
VGGFAKWPDSHPDAL	PGGT1B	306	P53609
SGAAETKPHPAEGQW	TAPBPL	16	Q9BX59
FVTHQEPTPEGDGSW	PRUNE2	2236	Q8WUY3
GKGTESHPPEDSWLK	TAB1	41	Q15750
EPWHGENAKGESGQS	SEMG1	396	P04279
GHWDEDSVVSSPDPG	SIM1	526	P81133
AHADGSWPPSKDGAS	SHROOM2	391	Q13796
VDTAPKSEWEASPGG	SLC38A7	31	Q9NVC3
WEQKVGGVSPEEHPA	SSH3	476	Q8TE77
EWASSDAQHGPQGKE	AHNAK2	201	Q8IVF2
EGSTVGPKPDSSWEA	LINC01561	31	Q8N1V8
EADTGSLHDPSPWVK	C11orf53	206	Q8IXP5
SLHDPSPWVKEDGSI	C11orf53	211	Q8IXP5
WITAGEHAKEGECPP	WFDC3	21	Q8IUB2
DPDGEEGSSIPWNHL	ZNF24	31	P17028
GSWIPPGEKEHGQES	ZNF691	61	Q5VV52
PEEDPRGKHAFQTGW	ZNF287	146	Q9HBT7
REGTKDSHDPLPSWA	PBXIP1	561	Q96AQ6
LAWNPEESTGGPHSA	TNFAIP3	446	P21580
DGESVWHPVSSGIPD	SPEG	2716	Q15772
HREEKVTAGWPSEPG	RREB1	1631	Q92766
SPLPDAFKHVGWEGA	SLC7A1	321	P30825
WPGAQEAPATGDKDS	FLT4	61	P35916
VQESWSDGPKPGADL	TMEM102	46	Q8N9M5
SPGKPEHLLEGSTWQ	HIVEP3	106	Q5T1R4
FIKQEPSWGGAEPHE	WT1	71	P19544
ETPSHPGGVSEEFWE	DHX38	116	Q92620
TAGKNGPVEPSHLWE	SNX19	176	Q92543
KDSPASNSGQEWPGE	SEC16B	186	Q96JE7
STPCPSVKHGDEWGE	UNKL	246	Q9H9P5
AEHLSSPWGESSPEE	WDR59	811	Q6PJI9
HEDISAGATPEPWGN	ZNF831	681	Q5JPB2
GEWVPAGKPEVSSHS	TBX19	106	O60806
HTGNSDNWREFKPGP	TUT7	106	Q5VYS8
AKETAEPSWGPQDEG	ZNF579	136	Q8NAF0
QEEGPTAFWKGHVPA	SLC25A19	71	Q9HC21
PEGTWTEGAPVKAAE	WNK4	106	Q96J92
HWPGAPEDQDDKDGG	SULF2	566	Q8IWU5
GTPSIEDAESWHAKP	TKTL1	221	P51854
GEGPWTLEGEAPHQS	ZNF81	76	P51508
PDWPSHSEDASALQG	GOLGB1	1286	Q14789
EGHPAPQISWQKDGG	LRIG2	626	O94898
GSSPHSVPDEDEGWL	PDE4DIP	1406	Q5VU43
TWTPPKDDGNAAITG	MYBPC1	951	Q00872